vesiculovirus

Summary

Summary: A genus of the family RHABDOVIRIDAE that infects a wide range of vertebrates and invertebrates. The type species is VESICULAR STOMATITIS INDIANA VIRUS.

Top Publications

  1. Nayak D, Panda D, Das S, Luo M, Pattnaik A. Single-amino-acid alterations in a highly conserved central region of vesicular stomatitis virus N protein differentially affect the viral nucleocapsid template functions. J Virol. 2009;83:5525-34 pubmed publisher
    ..These results suggest that the structure of the N protein and the resulting N-RNA complex, in part, regulate the viral template functions in transcription and replication...
  2. Chen H, Liu H, Liu Z, He J, Gao L, Shi X, et al. Characterization of the complete genome sequence of pike fry rhabdovirus. Arch Virol. 2009;154:1489-94 pubmed publisher
    ..3 to 91.4%. Phylogenetic analysis of the five proteins showed that PFRV clusters with SVCV and is closely related to the mammalian vesiculoviruses, 903/87, STRV and SCRV...
  3. Wang C, Chen T, Zhang J, Yang M, Li N, Xu X, et al. The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol. 2009;10:744-52 pubmed publisher
    ..Our data suggest that Nrdp1 functions as both an adaptor protein and an E3 unbiquitin ligase to regulate TLR responses in different ways...
  4. Rajan J, Rodriguez D, Miao E, Aderem A. The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection. J Virol. 2011;85:4167-72 pubmed publisher
    ..These findings indicate that the NLRP3 inflammasome may be a common pathway for RNA virus detection, but its precise role in the host response may be variable...
  5. Li J, Rahmeh A, Brusic V, Whelan S. Opposing effects of inhibiting cap addition and cap methylation on polyadenylation during vesicular stomatitis virus mRNA synthesis. J Virol. 2009;83:1930-40 pubmed publisher
    ..This work reveals that inhibiting cap addition and cap methylation have opposing effects on polyadenylation during VSV mRNA synthesis and provides evidence in support of a link between correct 5' cap formation and 3' polyadenylation...
  6. Detje C, Meyer T, Schmidt H, Kreuz D, Rose J, Bechmann I, et al. Local type I IFN receptor signaling protects against virus spread within the central nervous system. J Immunol. 2009;182:2297-304 pubmed publisher
    ..Our data indicate that upon intranasal VSV instillation, early and localized IFNAR triggering in the glomerular layer of the olfactory bulb is critically required to prevent viral spread over the entire CNS and thus confers survival...
  7. Chattopadhyay A, Rose J. Complementing defective viruses that express separate paramyxovirus glycoproteins provide a new vaccine vector approach. J Virol. 2011;85:2004-11 pubmed publisher
    ..Such an approach minimizes biosafety concerns that could apply to single, replication-competent VSV recombinants expressing all proteins required for infection...
  8. Gurav Y, Tandale B, Jadi R, Gunjikar R, Tikute S, Jamgaonkar A, et al. Chandipura virus encephalitis outbreak among children in Nagpur division, Maharashtra, 2007. Indian J Med Res. 2010;132:395-9 pubmed
    ..7%) and diarrhoea (23.7%). CHPV RNA was detected in one of two pools of sandflies from affected locality. Chandipura virus was confirmed as the aetiological agent of this acute encephalitis outbreak with high case-fatality among children...
  9. Green T, Rowse M, Tsao J, Kang J, Ge P, Zhou Z, et al. Access to RNA encapsidated in the nucleocapsid of vesicular stomatitis virus. J Virol. 2011;85:2714-22 pubmed publisher
    ..Polyribonucleotides were reencapsidated into the empty NLP, and the crystal structures were determined. The crystal structures revealed variable degrees of association of the N protein with a specific RNA sequence...
  10. Hoffmann M, Wu Y, Gerber M, Berger Rentsch M, Heimrich B, Schwemmle M, et al. Fusion-active glycoprotein G mediates the cytotoxicity of vesicular stomatitis virus M mutants lacking host shut-off activity. J Gen Virol. 2010;91:2782-93 pubmed publisher
    ..These findings indicate that the host shut-off activity of the M protein dominates VSV cytotoxicty, whilst the fusion-active G protein is mainly responsible for the cytotoxicity remaining with M-mutant VSV...

Detail Information

Publications62

  1. Nayak D, Panda D, Das S, Luo M, Pattnaik A. Single-amino-acid alterations in a highly conserved central region of vesicular stomatitis virus N protein differentially affect the viral nucleocapsid template functions. J Virol. 2009;83:5525-34 pubmed publisher
    ..These results suggest that the structure of the N protein and the resulting N-RNA complex, in part, regulate the viral template functions in transcription and replication...
  2. Chen H, Liu H, Liu Z, He J, Gao L, Shi X, et al. Characterization of the complete genome sequence of pike fry rhabdovirus. Arch Virol. 2009;154:1489-94 pubmed publisher
    ..3 to 91.4%. Phylogenetic analysis of the five proteins showed that PFRV clusters with SVCV and is closely related to the mammalian vesiculoviruses, 903/87, STRV and SCRV...
  3. Wang C, Chen T, Zhang J, Yang M, Li N, Xu X, et al. The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol. 2009;10:744-52 pubmed publisher
    ..Our data suggest that Nrdp1 functions as both an adaptor protein and an E3 unbiquitin ligase to regulate TLR responses in different ways...
  4. Rajan J, Rodriguez D, Miao E, Aderem A. The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection. J Virol. 2011;85:4167-72 pubmed publisher
    ..These findings indicate that the NLRP3 inflammasome may be a common pathway for RNA virus detection, but its precise role in the host response may be variable...
  5. Li J, Rahmeh A, Brusic V, Whelan S. Opposing effects of inhibiting cap addition and cap methylation on polyadenylation during vesicular stomatitis virus mRNA synthesis. J Virol. 2009;83:1930-40 pubmed publisher
    ..This work reveals that inhibiting cap addition and cap methylation have opposing effects on polyadenylation during VSV mRNA synthesis and provides evidence in support of a link between correct 5' cap formation and 3' polyadenylation...
  6. Detje C, Meyer T, Schmidt H, Kreuz D, Rose J, Bechmann I, et al. Local type I IFN receptor signaling protects against virus spread within the central nervous system. J Immunol. 2009;182:2297-304 pubmed publisher
    ..Our data indicate that upon intranasal VSV instillation, early and localized IFNAR triggering in the glomerular layer of the olfactory bulb is critically required to prevent viral spread over the entire CNS and thus confers survival...
  7. Chattopadhyay A, Rose J. Complementing defective viruses that express separate paramyxovirus glycoproteins provide a new vaccine vector approach. J Virol. 2011;85:2004-11 pubmed publisher
    ..Such an approach minimizes biosafety concerns that could apply to single, replication-competent VSV recombinants expressing all proteins required for infection...
  8. Gurav Y, Tandale B, Jadi R, Gunjikar R, Tikute S, Jamgaonkar A, et al. Chandipura virus encephalitis outbreak among children in Nagpur division, Maharashtra, 2007. Indian J Med Res. 2010;132:395-9 pubmed
    ..7%) and diarrhoea (23.7%). CHPV RNA was detected in one of two pools of sandflies from affected locality. Chandipura virus was confirmed as the aetiological agent of this acute encephalitis outbreak with high case-fatality among children...
  9. Green T, Rowse M, Tsao J, Kang J, Ge P, Zhou Z, et al. Access to RNA encapsidated in the nucleocapsid of vesicular stomatitis virus. J Virol. 2011;85:2714-22 pubmed publisher
    ..Polyribonucleotides were reencapsidated into the empty NLP, and the crystal structures were determined. The crystal structures revealed variable degrees of association of the N protein with a specific RNA sequence...
  10. Hoffmann M, Wu Y, Gerber M, Berger Rentsch M, Heimrich B, Schwemmle M, et al. Fusion-active glycoprotein G mediates the cytotoxicity of vesicular stomatitis virus M mutants lacking host shut-off activity. J Gen Virol. 2010;91:2782-93 pubmed publisher
    ..These findings indicate that the host shut-off activity of the M protein dominates VSV cytotoxicty, whilst the fusion-active G protein is mainly responsible for the cytotoxicity remaining with M-mutant VSV...
  11. Padhi A, Verghese B. Molecular evolutionary and epidemiological dynamics of a highly pathogenic fish rhabdovirus, the spring viremia of carp virus (SVCV). Vet Microbiol. 2012;156:54-63 pubmed publisher
    ....
  12. Venkateswarlu C, Arankalle V. Recombinant glycoprotein based vaccine for Chandipura virus infection. Vaccine. 2009;27:2845-50 pubmed publisher
    ..There was 60% T cell proliferation observed against rGp in immunized mice. The study shows that rGp induces both arms of immune response and represents an ideal vaccine candidate for further evaluations...
  13. Mire C, Dube D, Delos S, White J, Whitt M. Glycoprotein-dependent acidification of vesicular stomatitis virus enhances release of matrix protein. J Virol. 2009;83:12139-50 pubmed publisher
    ..From these data we propose that low-pH conformational changes in G protein promote acidification of the virus interior, which facilitates the release of M from ribonucleoprotein particles during uncoating...