avulavirus

Summary

Summary: A genus in the subfamily PARAMYXOVIRINAE, family PARAMYXOVIRIDAE, causing disease in domestic fowl. There are many species, the most well-known being avian paramyxovirus 1 (NEWCASTLE DISEASE VIRUS).

Top Publications

  1. Jinding C, Ming L, Tao R, Chaoan X. A goose-sourced paramyxovirus isolated from southern China. Avian Dis. 2005;49:170-3 pubmed
    ..8% to 99.6% on an amino acid basis. Phylogenetic analysis of the APMV-1 isolates showed that this isolate most closely resembled the reference APMV-1 strain GD/1/98/Go, which was originally isolated from geese in 1998...
  2. Zhang G, Zhao J, Wang H, Yang A, Bu C, Wang M. Isolation, identification, and comparison of four isolates of avian paramyxovirus serotype 2 in China. Avian Dis. 2006;50:386-90 pubmed
    ..By sequence comparison, it was also revealed that at the molecular level the four virus strains belong to APMV-2, and that two of the strains were isolated from the same group of imported Gouldian Finches...
  3. Paldurai A, Subbiah M, Kumar S, Collins P, Samal S. Complete genome sequences of avian paramyxovirus type 8 strains goose/Delaware/1053/76 and pintail/Wakuya/20/78. Virus Res. 2009;142:144-53 pubmed publisher
  4. Kim S, Xiao S, Shive H, Collins P, Samal S. Mutations in the fusion protein cleavage site of avian paramyxovirus serotype 4 confer increased replication and syncytium formation in vitro but not increased replication and pathogenicity in chickens and ducks. PLoS ONE. 2013;8:e50598 pubmed publisher
    ..These results suggested that the cleavage site sequence of the F protein is not a limiting determinant of APMV-4 pathogenicity in chickens and ducks...
  5. Kim S, Xiao S, Shive H, Collins P, Samal S. Replication, neurotropism, and pathogenicity of avian paramyxovirus serotypes 1-9 in chickens and ducks. PLoS ONE. 2012;7:e34927 pubmed publisher
    ..The link between the presence of a furin cleavage site in the F protein, syncytium formation, systemic spread, and virulence that has been well-established with APMV-1 pathotypes was not evident with the other APMV serotypes...
  6. Nayak B, Dias F, Kumar S, Paldurai A, Collins P, Samal S. Avian paramyxovirus serotypes 2-9 (APMV-2-9) vary in the ability to induce protective immunity in chickens against challenge with virulent Newcastle disease virus (APMV-1). Vaccine. 2012;30:2220-7 pubmed publisher
    The avian paramyxoviruses (APMVs) belong to the genus Avulavirus of family Paramyxoviridae...
  7. Beck I, Gerlach H, Burkhardt E, Kaleta E. Investigation of several selected adjuvants regarding their efficacy and side effects for the production of a vaccine for parakeets to prevent a disease caused by a paramyxovirus type 3. Vaccine. 2003;21:1006-22 pubmed
    ..Regarding its efficacy and side effects, the vaccine formulation "PMV-3/Specol" has been evaluated positively and can be recommended for the production of a PMV-3 vaccine for parakeets...
  8. Kaleta E, Werner O, Hemberger Y. Isolation and characterization of avian paramyxovirus type 3b from farmed Namibian ostriches (Struthio camelus f. dom.). Berl Munch Tierarztl Wochenschr. 2010;123:103-10 pubmed
    ..To our knowledge, this is the first description of the occurrence of aPMV-3b in farmed ostriches...
  9. Warke A, Appleby L, Mundt E. Prevalence of antibodies to different avian paramyxoviruses in commercial poultry in the United States. Avian Dis. 2008;52:694-7 pubmed
  10. Subbiah M, Xiao S, Khattar S, Dias F, Collins P, Samal S. Pathogenesis of two strains of avian paramyxovirus serotype 2, Yucaipa and Bangor, in chickens and turkeys. Avian Dis. 2010;54:1050-7 pubmed
    ..There also was evidence of systemic spread even though the cleavage site of the viral fusion glycoprotein does not contain the canonical furin protease cleavage site...

Detail Information

Publications75

  1. Jinding C, Ming L, Tao R, Chaoan X. A goose-sourced paramyxovirus isolated from southern China. Avian Dis. 2005;49:170-3 pubmed
    ..8% to 99.6% on an amino acid basis. Phylogenetic analysis of the APMV-1 isolates showed that this isolate most closely resembled the reference APMV-1 strain GD/1/98/Go, which was originally isolated from geese in 1998...
  2. Zhang G, Zhao J, Wang H, Yang A, Bu C, Wang M. Isolation, identification, and comparison of four isolates of avian paramyxovirus serotype 2 in China. Avian Dis. 2006;50:386-90 pubmed
    ..By sequence comparison, it was also revealed that at the molecular level the four virus strains belong to APMV-2, and that two of the strains were isolated from the same group of imported Gouldian Finches...
  3. Paldurai A, Subbiah M, Kumar S, Collins P, Samal S. Complete genome sequences of avian paramyxovirus type 8 strains goose/Delaware/1053/76 and pintail/Wakuya/20/78. Virus Res. 2009;142:144-53 pubmed publisher
  4. Kim S, Xiao S, Shive H, Collins P, Samal S. Mutations in the fusion protein cleavage site of avian paramyxovirus serotype 4 confer increased replication and syncytium formation in vitro but not increased replication and pathogenicity in chickens and ducks. PLoS ONE. 2013;8:e50598 pubmed publisher
    ..These results suggested that the cleavage site sequence of the F protein is not a limiting determinant of APMV-4 pathogenicity in chickens and ducks...
  5. Kim S, Xiao S, Shive H, Collins P, Samal S. Replication, neurotropism, and pathogenicity of avian paramyxovirus serotypes 1-9 in chickens and ducks. PLoS ONE. 2012;7:e34927 pubmed publisher
    ..The link between the presence of a furin cleavage site in the F protein, syncytium formation, systemic spread, and virulence that has been well-established with APMV-1 pathotypes was not evident with the other APMV serotypes...
  6. Nayak B, Dias F, Kumar S, Paldurai A, Collins P, Samal S. Avian paramyxovirus serotypes 2-9 (APMV-2-9) vary in the ability to induce protective immunity in chickens against challenge with virulent Newcastle disease virus (APMV-1). Vaccine. 2012;30:2220-7 pubmed publisher
    The avian paramyxoviruses (APMVs) belong to the genus Avulavirus of family Paramyxoviridae...
  7. Beck I, Gerlach H, Burkhardt E, Kaleta E. Investigation of several selected adjuvants regarding their efficacy and side effects for the production of a vaccine for parakeets to prevent a disease caused by a paramyxovirus type 3. Vaccine. 2003;21:1006-22 pubmed
    ..Regarding its efficacy and side effects, the vaccine formulation "PMV-3/Specol" has been evaluated positively and can be recommended for the production of a PMV-3 vaccine for parakeets...
  8. Kaleta E, Werner O, Hemberger Y. Isolation and characterization of avian paramyxovirus type 3b from farmed Namibian ostriches (Struthio camelus f. dom.). Berl Munch Tierarztl Wochenschr. 2010;123:103-10 pubmed
    ..To our knowledge, this is the first description of the occurrence of aPMV-3b in farmed ostriches...
  9. Warke A, Appleby L, Mundt E. Prevalence of antibodies to different avian paramyxoviruses in commercial poultry in the United States. Avian Dis. 2008;52:694-7 pubmed
  10. Subbiah M, Xiao S, Khattar S, Dias F, Collins P, Samal S. Pathogenesis of two strains of avian paramyxovirus serotype 2, Yucaipa and Bangor, in chickens and turkeys. Avian Dis. 2010;54:1050-7 pubmed
    ..There also was evidence of systemic spread even though the cleavage site of the viral fusion glycoprotein does not contain the canonical furin protease cleavage site...
  11. Kumar S, Nayak B, Collins P, Samal S. Evaluation of the Newcastle disease virus F and HN proteins in protective immunity by using a recombinant avian paramyxovirus type 3 vector in chickens. J Virol. 2011;85:6521-34 pubmed publisher
    ..rAMPV3 represents an avirulent vaccine vector that can be used against NDV and other poultry pathogens...
  12. Nayak B, Kumar S, Collins P, Samal S. Molecular characterization and complete genome sequence of avian paramyxovirus type 4 prototype strain duck/Hong Kong/D3/75. Virol J. 2008;5:124 pubmed publisher
    ..All APMVs, except avian metapneumovirus, are classified in the genus Avulavirus of the family Paramyxoviridae...
  13. Miller P, Afonso C, Spackman E, Scott M, Pedersen J, Senne D, et al. Evidence for a new avian paramyxovirus serotype 10 detected in rockhopper penguins from the Falkland Islands. J Virol. 2010;84:11496-504 pubmed publisher
  14. Zhang G, Zhao J, Wang M. Serological survey on prevalence of antibodies to avian paramyxovirus serotype 2 in China. Avian Dis. 2007;51:137-9 pubmed
    ..9%, 25.1%, 45.8%, 47.6%, and 80.0%, respectively. The results of this survey indicate that the distribution of APMV-2 is very widespread in China and that more attention should be paid to the influence of APMV-2 on poultry production...
  15. Samuel A, Paldurai A, Kumar S, Collins P, Samal S. Complete genome sequence of avian paramyxovirus (APMV) serotype 5 completes the analysis of nine APMV serotypes and reveals the longest APMV genome. PLoS ONE. 2010;5:e9269 pubmed publisher
    ..The genome is 17,262 nucleotides (nt) long, which is the longest among members of genus Avulavirus, and encodes six non-overlapping genes in the order of 3'N-P/V/W-M-F-HN-L-5' with intergenic regions of 4-57 nt...
  16. Kumar S, Militino Dias F, Nayak B, Collins P, Samal S. Experimental avian paramyxovirus serotype-3 infection in chickens and turkeys. Vet Res. 2010;41:72 pubmed publisher
    ..Furthermore, there was little or no disease despite systemic viral spread and abundant viral replication in all the tissues tested...
  17. Rosseel T, Lambrecht B, Vandenbussche F, van den Berg T, Van Borm S. Identification and complete genome sequencing of paramyxoviruses in mallard ducks (Anas platyrhynchos) using random access amplification and next generation sequencing technologies. Virol J. 2011;8:463 pubmed publisher
    ..AIV and APMV1 were excluded using hemagglutination inhibition (HI) testing and specific real-time RT-PCR tests...
  18. Shihmanter E, Weisman Y, Manwell R, Alexander D, Lipkind M. Mixed paramyxovirus infection of wild and domestic birds in Israel. Vet Microbiol. 1997;58:73-8 pubmed
    ..The finding of double APMV infection in poultry farms appears to be important for epizootiology and pathogenesis of APMV-caused diseases...
  19. Xiao S, Paldurai A, Nayak B, Subbiah M, Collins P, Samal S. Complete genome sequence of avian paramyxovirus type 7 (strain Tennessee) and comparison with other paramyxoviruses. Virus Res. 2009;145:80-91 pubmed publisher
    ..The mean death time in embryonated chicken eggs was found to be more than 144h, indicating APMV-7 to be avirulent for chickens. ..
  20. Samuel A, Kumar S, Madhuri S, Collins P, Samal S. Complete sequence of the genome of avian paramyxovirus type 9 and comparison with other paramyxoviruses. Virus Res. 2009;142:10-8 pubmed publisher
    ..The mean death time in embryonated chicken eggs was found to be more than 120h, indicating APMV-9 to be avirulent for chickens. ..
  21. Jung A, Grund C, Müller I, Rautenschlein S. Avian paramyxovirus serotype 3 infection in Neopsephotus, Cyanoramphus, and Neophema species. J Avian Med Surg. 2009;23:205-8 pubmed
    ..An eventual mortality rate of 70% occurred in the Neophema species, but a group of budgerigars (Melopsittacus undulatus) and parrotlets (Forpus species) kept in the same facility showed no clinical signs during the outbreak...
  22. Subbiah M, Khattar S, Collins P, Samal S. Mutations in the fusion protein cleavage site of avian paramyxovirus serotype 2 increase cleavability and syncytium formation but do not increase viral virulence in chickens. J Virol. 2011;85:5394-405 pubmed publisher
    ..Furthermore, cleavage of the F protein is not a determinant of APMV-2 pathogenicity in chickens...
  23. Kumar S, Nayak B, Samuel A, Xiao S, Collins P, Samal S. Complete genome sequence of avian paramyxovirus-3 strain Wisconsin: evidence for the existence of subgroups within the serotype. Virus Res. 2010;149:78-85 pubmed publisher
    ..Taken together, our results indicate that the two APMV-3 strains represent a single serotype with two subgroups that differ substantially based on nt and aa sequences, but with only a modest antigenic difference. ..
  24. Hanson B, Swayne D, Senne D, Lobpries D, Hurst J, Stallknecht D. Avian influenza viruses and paramyxoviruses in wintering and resident ducks in Texas. J Wildl Dis. 2005;41:624-8 pubmed
    ..7% of teal in February 2002. The season of isolation of both viruses and the majority of the AIV subtypes detected in this study are not typical based on previous reports of these viruses from North American ducks...
  25. Wajid A, Dimitrov K, Wasim M, Rehmani S, Basharat A, Bibi T, et al. Repeated isolation of virulent Newcastle disease viruses in poultry and captive non-poultry avian species in Pakistan from 2011 to 2016. Prev Vet Med. 2017;142:1-6 pubmed publisher
    Virulent viruses of the panzootic Avian avulavirus 1 (AAvV-1) of sub-genotype VIIi were repeatedly isolated (2011-2016) from commercial chickens and from multiple non-poultry avian species in Pakistan...
  26. Kong L, Ren T, Ao Y, Xi R, Liao M. Multiplex RT-PCR for virulence detection and differentiation between Newcastle disease virus and goose-origin APVM-1. Avian Dis. 2007;51:668-73 pubmed
    ..Twenty-six viral isolates of NDV and four goose-origin APVM-1 were analyzed, and we found that the VII genotype of NDV is the most prevalent type in South China and that it is not closely related to viral strains common to Europe...
  27. Bui V, Mizutani T, Nguyen T, Trinh D, Awad S, Minoungou G, et al. Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis). Arch Virol. 2014;159:3101-5 pubmed publisher
    ..8KS0813 was identified as APMV-6/red-necked stint/Japan/8KS0813/08, but it is antigenically and genetically distinguishable from the prototype strain, suggesting that variant APMV-6 is circulating in migratory birds...
  28. Connor J, McKenzie M, Parks G, Lyles D. Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses. Virology. 2007;362:109-19 pubmed
    ..Based on these results, we propose that Hsp90 is a host factor that is important for the replication of many negative strand viruses. ..
  29. Orynbayev M, Fereidouni S, Sansyzbai A, Seidakhmetova B, Strochkov V, Nametov A, et al. Genetic diversity of avian avulavirus 1 (Newcastle disease virus genotypes VIg and VIIb) circulating in wild birds in Kazakhstan. Arch Virol. 2018;: pubmed publisher
    In order to improve current understanding of the molecular epidemiology of avian avulavirus 1 (AAvV-1, formerly avian paramyxovirus 1) in wild birds in Kazakhstan, 860 cloacal swab samples were evaluated...
  30. Thampaisarn R, Bui V, Trinh D, Nagai M, Mizutani T, Omatsu T, et al. Characterization of avian paramyxovirus serotype 14, a novel serotype, isolated from a duck fecal sample in Japan. Virus Res. 2017;228:46-57 pubmed publisher
    ..The phylogenetic analysis of the whole genome revealed that the virus was a member of the genus Avulavirus, but that it was distinct from APMV-1 to APMV-13...
  31. Karamendin K, Kydyrmanov A, Seidalina A, Asanova S, Daulbayeva K, Kasymbekov Y, et al. Circulation of avian paramyxoviruses in wild birds of Kazakhstan in 2002-2013. Virol J. 2016;13:23 pubmed publisher
    ..These data confirm the wide distribution of APMV-1, APMV-4 and APMV-6 in the Asian subcontinent. The obtained data contribute to the accumulation of knowledge on the genetic diversity and prevalence of APMVs in wild bird populations. ..
  32. Briand F, Henry A, Massin P, Jestin V. Complete genome sequence of a novel avian paramyxovirus. J Virol. 2012;86:7710 pubmed publisher
    ..We report here the complete genome of a new avian paramyxovirus (APMV-11) isolated from common snipes. Sequence data from this virus showed that it has the largest genome of APMV and unusual P gene mRNA editing. ..
  33. Blahak S. Isolation and characterization of paramyxoviruses from snakes and their relationship to avian paramyxoviruses. Zentralbl Veterinarmed B. 1995;42:216-24 pubmed
    ..At 28 degrees C the snake viruses could be cultivated in several cell cultures. Separation of virus proteins using polyacrylamide gel electrophoresis showed differences between the snake isolates and avian PMVs of serotypes 1 and 7. ..
  34. Sobolev I, Sharshov K, Yurchenko K, Korneev D, Glushchenko A, Alikina T, et al. Characterization of avian paramyxovirus type 6 isolated from a Eurasian teal in the intersection of migratory flyways in Russia. Arch Virol. 2016;161:3275-9 pubmed publisher
    ..We show that the virus has low pathogenic potential according to genetic markers and animal model experiments. ..
  35. Fornells L, Travassos C, Costa C, Novelli R, Petrucci M, Soffiati F, et al. Detection of avian paramyxoviruses in migratory and resident birds in the state of Rio de Janeiro, Brazil. Avian Dis. 2013;57:780-4 pubmed
    ..Four samples were characterized as avian paramyxovirus serotype-2 (APMV-2) by a hemagglutination inhibition test. These results reinforce the importance of continuous surveillance of wild species in Brazil...
  36. Terregino C, Aldous E, Heidari A, Fuller C, De Nardi R, Manvell R, et al. Antigenic and genetic analyses of isolate APMV/wigeon/Italy/3920-1/2005 indicate that it represents a new avian paramyxovirus (APMV-12). Arch Virol. 2013;158:2233-43 pubmed publisher
    ..1 % identity to the APMV-9 genome, and less than 42 % identity to representatives of the other avian paramyxovirus groups. We propose isolate wigeon/Italy/3920-1/2005 as the prototype strain of a further APMV group, APMV-12...
  37. Abolnik C, de Castro M, Rees J. Full genomic sequence of an African avian paramyxovirus type 4 strain isolated from a wild duck. Virus Genes. 2012;45:537-41 pubmed publisher
    ..The sequencing approach adopted in this study could successfully indicate quasispecies in the viral stock...
  38. Mahmood S, Alexander D, Slomka M, Manvell R, Hanna A, Fuller C, et al. Phylogenetic analysis of the nucleotide sequences for the HN gene of 22 avian paramyxovirus type 2 viruses reveals marked heterogeneity. Avian Pathol. 2010;39:453-8 pubmed publisher
  39. Tsai H, Lee C. Serological survey of racing pigeons for selected pathogens in Taiwan. Acta Vet Hung. 2006;54:179-89 pubmed
    ..ND or EDS-76 seroprevalence of pigeons vaccinated with ND vaccine or EDS-76 vaccine was significantly higher than that of pigeons that did not receive any vaccination...
  40. Wood A, Dagless M, Pirie J, Garcia Rueda M, Manvell R, Cox W, et al. Isolations of avian paramyxovirus type 2 from domestic fowl in Scotland in 2002 and 2006. Vet Rec. 2008;162:788-9 pubmed
  41. Subbiah M, Nayak S, Collins P, Samal S. Complete genome sequences of avian paramyxovirus serotype 2 (APMV-2) strains Bangor, England and Kenya: evidence for the existence of subgroups within serotype 2. Virus Res. 2010;152:85-95 pubmed publisher
    ..These differences in antigenic relatedness suggest that these four APMV-2 strains represent a single serotype with two antigenic subgroups, and this is strongly supported by the dimorphism in nt and aa sequence identity. ..
  42. Khattar S, Nayak B, Kim S, Xiao S, Samal S, Paldurai A, et al. Evaluation of the replication, pathogenicity, and immunogenicity of avian paramyxovirus (APMV) serotypes 2, 3, 4, 5, 7, and 9 in rhesus macaques. PLoS ONE. 2013;8:e75456 pubmed publisher
    ..This suggests that they are not likely to significantly infect primates in nature, and represent promising attenuated candidates for vector development. ..
  43. Goekjian V, Smith J, Howell D, Senne D, Swayne D, Stallknecht D. Avian influenza viruses and avian paramyxoviruses in wintering and breeding waterfowl populations in North Carolina, USA. J Wildl Dis. 2011;47:240-5 pubmed
    ..During summers 2005 and 2006, a high prevalence of APMV-1 infection was observed in resident breeding Wood Ducks (Aix sponsa) and Mallards (Anas platyrhynchos)...
  44. Choi K, Kim J, Kye S, Park C, Sung H. Genetic diversity of avian paramyxovirus type 4 isolates from wild ducks in Korea from 2006 to 2011. Virus Genes. 2013;46:302-8 pubmed publisher
  45. Li X, Zhang S, Wang H, Zhao J, Zhang G. Genomic characterization of two avian paramyxovirus type 2 isolates from chickens in China. Virus Genes. 2011;43:55-9 pubmed publisher
    ..Among the APMVs, APMV-2 strains F8 and NK exhibited a closer evolutionary relationship with APMV-7 and APMV-8 representative strains...
  46. Thomazelli L, de Araujo J, Fabrizio T, Walker D, Reischak D, Ometto T, et al. Novel avian paramyxovirus (APMV-15) isolated from a migratory bird in South America. PLoS ONE. 2017;12:e0177214 pubmed publisher
    ..These results suggest that unclassified/calidris_fuscicollis/Brazil/RS-1177/2012 is the prototype strain of a new APMV serotype, APMV-15. ..
  47. Dundon W, Heidari A, Fusaro A, Monne I, Beato M, Cattoli G, et al. Genetic data from avian influenza and avian paramyxoviruses generated by the European network of excellence (EPIZONE) between 2006 and 2011--review and recommendations for surveillance. Vet Microbiol. 2012;154:209-21 pubmed publisher
    ..Based on this information and putting it all into a European context, recommendations for continued surveillance of these important viruses within Europe are presented...