newcastle disease

Summary

Summary: An acute febrile, contagious, viral disease of birds caused by an AVULAVIRUS called NEWCASTLE DISEASE VIRUS. It is characterized by respiratory and nervous symptoms in fowl and is transmissible to man causing a severe, but transient conjunctivitis.

Top Publications

  1. Cho S, Kwon H, Kim T, Kim J, Yoo H, Park M, et al. Characterization of a recombinant Newcastle disease virus vaccine strain. Clin Vaccine Immunol. 2008;15:1572-9 pubmed publisher
    ..Therefore, KBNP-C4152R2L is a promising vaccine strain and viral vector in terms of antigenicity, productivity, safety, and pathogenic stability. ..
  2. Courtney S, Susta L, Gomez D, Hines N, Pedersen J, Brown C, et al. Highly divergent virulent isolates of Newcastle disease virus from the Dominican Republic are members of a new genotype that may have evolved unnoticed for over 2 decades. J Clin Microbiol. 2013;51:508-17 pubmed publisher
    A Newcastle disease virus (NDV) outbreak in chickens was reported in the Dominican Republic in 2008...
  3. Bwala D, Clift S, Duncan N, Bisschop S, Oludayo F. Determination of the distribution of lentogenic vaccine and virulent Newcastle disease virus antigen in the oviduct of SPF and commercial hen using immunohistochemistry. Res Vet Sci. 2012;93:520-8 pubmed publisher
    The control of Newcastle disease (ND) in South Africa has proved difficult since 2002 following the introduction of lineage 5d/VIId Newcastle disease virus (NDV) strain ("goose paramyxovirus" - GPMV) to which commercially ..
  4. Cornax I, Diel D, Rue C, Estevez C, Yu Q, Miller P, et al. Newcastle disease virus fusion and haemagglutinin-neuraminidase proteins contribute to its macrophage host range. J Gen Virol. 2013;94:1189-1194 pubmed publisher
    The fusion (F) and haemagglutinin-neuraminidase (HN) proteins of Newcastle disease virus (NDV) are multifunctional proteins that play critical roles during infection...
  5. Hoque M, Burgess G, Karo Karo D, Cheam A, Skerratt L. Monitoring of wild birds for Newcastle disease virus in north Queensland, Australia. Prev Vet Med. 2012;103:49-62 pubmed publisher
    Wild aquatic birds (WABs) are considered as reservoir hosts for Newcastle disease viruses (NDVs) and may act as vectors for transferring these viruses to poultry, causing outbreaks of disease...
  6. Otim M, Kabagambe E, Mukiibi G, Christensen H, Bisgaard M. A study of risk factors associated with Newcastle disease epidemics in village free-range chickens in Uganda. Trop Anim Health Prod. 2007;39:27-35 pubmed
    A prospective study of risk factors associated with outbreaks of Newcastle disease (ND) in indigenous free-range chickens was carried out in three agro-ecological zones in eastern Uganda...
  7. Ahmed K, Saxena V, Ara A, Singh K, Sundaresan N, Saxena M, et al. Immune response to Newcastle disease virus in chicken lines divergently selected for cutaneous hypersensitivity. Int J Immunogenet. 2007;34:445-55 pubmed
    This paper describes for the first time the differential immune response to virulent Newcastle disease virus (NDV) in birds differing in cell-mediated immunity, as measured by response to phytohaemagglutinin-P...
  8. Pchelkina I, Manin T, Kolosov S, Starov S, Andriyasov A, Chvala I, et al. Characteristics of pigeon paramyxovirus serotype-1 isolates (PPMV-1) from the Russian Federation from 2001 to 2009. Avian Dis. 2013;57:2-7 pubmed
    ..It was determined that most of these Newcastle disease virus isolates (70/77) recovered from the pigeons belonged to a relatively poorly studied sublineage VIb/2...
  9. Chimeno Zoth S, Gómez E, Carballeda J, Taboga O, Carrillo E, Berinstein A. Potential use of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus expressed in Rachiplusia nu larvae as an immunogen for chickens. Clin Vaccine Immunol. 2009;16:775-8 pubmed publisher
    The hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus (NDV) was obtained as a recombinant antigen in Rachiplusia nu larvae...
  10. Samal S, Khattar S, Kumar S, Collins P, Samal S. Coordinate deletion of N-glycans from the heptad repeats of the fusion F protein of Newcastle disease virus yields a hyperfusogenic virus with increased replication, virulence, and immunogenicity. J Virol. 2012;86:2501-11 pubmed publisher
    The role of N-linked glycosylation of the Newcastle disease virus (NDV) fusion (F) protein in viral replication and pathogenesis was examined by eliminating potential acceptor sites using a reverse genetics system for the moderately ..

Detail Information

Publications103 found, 100 shown here

  1. Cho S, Kwon H, Kim T, Kim J, Yoo H, Park M, et al. Characterization of a recombinant Newcastle disease virus vaccine strain. Clin Vaccine Immunol. 2008;15:1572-9 pubmed publisher
    ..Therefore, KBNP-C4152R2L is a promising vaccine strain and viral vector in terms of antigenicity, productivity, safety, and pathogenic stability. ..
  2. Courtney S, Susta L, Gomez D, Hines N, Pedersen J, Brown C, et al. Highly divergent virulent isolates of Newcastle disease virus from the Dominican Republic are members of a new genotype that may have evolved unnoticed for over 2 decades. J Clin Microbiol. 2013;51:508-17 pubmed publisher
    A Newcastle disease virus (NDV) outbreak in chickens was reported in the Dominican Republic in 2008...
  3. Bwala D, Clift S, Duncan N, Bisschop S, Oludayo F. Determination of the distribution of lentogenic vaccine and virulent Newcastle disease virus antigen in the oviduct of SPF and commercial hen using immunohistochemistry. Res Vet Sci. 2012;93:520-8 pubmed publisher
    The control of Newcastle disease (ND) in South Africa has proved difficult since 2002 following the introduction of lineage 5d/VIId Newcastle disease virus (NDV) strain ("goose paramyxovirus" - GPMV) to which commercially ..
  4. Cornax I, Diel D, Rue C, Estevez C, Yu Q, Miller P, et al. Newcastle disease virus fusion and haemagglutinin-neuraminidase proteins contribute to its macrophage host range. J Gen Virol. 2013;94:1189-1194 pubmed publisher
    The fusion (F) and haemagglutinin-neuraminidase (HN) proteins of Newcastle disease virus (NDV) are multifunctional proteins that play critical roles during infection...
  5. Hoque M, Burgess G, Karo Karo D, Cheam A, Skerratt L. Monitoring of wild birds for Newcastle disease virus in north Queensland, Australia. Prev Vet Med. 2012;103:49-62 pubmed publisher
    Wild aquatic birds (WABs) are considered as reservoir hosts for Newcastle disease viruses (NDVs) and may act as vectors for transferring these viruses to poultry, causing outbreaks of disease...
  6. Otim M, Kabagambe E, Mukiibi G, Christensen H, Bisgaard M. A study of risk factors associated with Newcastle disease epidemics in village free-range chickens in Uganda. Trop Anim Health Prod. 2007;39:27-35 pubmed
    A prospective study of risk factors associated with outbreaks of Newcastle disease (ND) in indigenous free-range chickens was carried out in three agro-ecological zones in eastern Uganda...
  7. Ahmed K, Saxena V, Ara A, Singh K, Sundaresan N, Saxena M, et al. Immune response to Newcastle disease virus in chicken lines divergently selected for cutaneous hypersensitivity. Int J Immunogenet. 2007;34:445-55 pubmed
    This paper describes for the first time the differential immune response to virulent Newcastle disease virus (NDV) in birds differing in cell-mediated immunity, as measured by response to phytohaemagglutinin-P...
  8. Pchelkina I, Manin T, Kolosov S, Starov S, Andriyasov A, Chvala I, et al. Characteristics of pigeon paramyxovirus serotype-1 isolates (PPMV-1) from the Russian Federation from 2001 to 2009. Avian Dis. 2013;57:2-7 pubmed
    ..It was determined that most of these Newcastle disease virus isolates (70/77) recovered from the pigeons belonged to a relatively poorly studied sublineage VIb/2...
  9. Chimeno Zoth S, Gómez E, Carballeda J, Taboga O, Carrillo E, Berinstein A. Potential use of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus expressed in Rachiplusia nu larvae as an immunogen for chickens. Clin Vaccine Immunol. 2009;16:775-8 pubmed publisher
    The hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus (NDV) was obtained as a recombinant antigen in Rachiplusia nu larvae...
  10. Samal S, Khattar S, Kumar S, Collins P, Samal S. Coordinate deletion of N-glycans from the heptad repeats of the fusion F protein of Newcastle disease virus yields a hyperfusogenic virus with increased replication, virulence, and immunogenicity. J Virol. 2012;86:2501-11 pubmed publisher
    The role of N-linked glycosylation of the Newcastle disease virus (NDV) fusion (F) protein in viral replication and pathogenesis was examined by eliminating potential acceptor sites using a reverse genetics system for the moderately ..
  11. Fuller C, Collins M, Easton A, Alexander D. Partial characterisation of five cloned viruses differing in pathogenicity, obtained from a single isolate of pigeon paramyxovirus type 1 (PPMV-1) following passage in fowls' eggs. Arch Virol. 2007;152:1575-82 pubmed
    ..49, T --> C at position 1769 in the untranslated region of the fusion gene and G --> A at position 437 of the HN gene, resulting in the amino acid change G --> R at position 116 in the HN protein. ..
  12. Cho S, Kwon H, Kim T, Kim J, Yoo H, Kim S. Variation of a newcastle disease virus hemagglutinin-neuraminidase linear epitope. J Clin Microbiol. 2008;46:1541-4 pubmed publisher
    Fifty-six Newcastle disease virus strains collected from 2000 to 2006 could be grouped into subgenotype VIId...
  13. Dortmans J, Koch G, Rottier P, Peeters B. Virulence of pigeon paramyxovirus type 1 does not always correlate with the cleavability of its fusion protein. J Gen Virol. 2009;90:2746-50 pubmed publisher
    ..By using reverse genetics, we exchanged the F genes of AV324 and a virulent Newcastle disease virus (NDV) strain (Herts) and evaluated the recovered chimeric viruses for their pathogenicity in 1-day-old ..
  14. Rauw F, Gardin Y, Palya V, Anbari S, Lemaire S, Boschmans M, et al. Improved vaccination against Newcastle disease by an in ovo recombinant HVT-ND combined with an adjuvanted live vaccine at day-old. Vaccine. 2010;28:823-33 pubmed publisher
    The continuous outbreaks of fatal Newcastle disease (ND) in commercial poultry flocks demonstrate that current vaccination strategies are not fully efficacious and should be improved by new generation of vaccines...
  15. Tan S, Ideris A, Omar A, Yusoff K, Hair Bejo M. Sequence and phylogenetic analysis of Newcastle disease virus genotypes isolated in Malaysia between 2004 and 2005. Arch Virol. 2010;155:63-70 pubmed publisher
    ..It is suggested that genotype VII viruses were responsible for most of the outbreaks in recent years. ..
  16. Pinette M, Rodriguez Lecompte J, Pasick J, Ojkic D, Leith M, Suderman M, et al. Development of a duplex Fluorescent Microsphere Immunoassay (FMIA) for the detection of antibody responses to influenza A and newcastle disease viruses. J Immunol Methods. 2014;405:167-77 pubmed publisher
    ..7%, and 97.3% respectively. The APMV-1 nucleocapsid relative diagnostic sensitivity and specificity were 95.4%, and 98.5% respectively. ..
  17. Bogoyavlenskiy A, Berezin V, Prilipov A, Usachev E, Lyapina O, Korotetskiy I, et al. Newcastle disease outbreaks in Kazakhstan and Kyrgyzstan during 1998, 2000, 2001, 2003, 2004, and 2005 were caused by viruses of the genotypes VIIb and VIId. Virus Genes. 2009;39:94-101 pubmed publisher
    b>Newcastle disease virus (NDV) infects domesticated and wild birds throughout the world, and infections with virulent NDV strains continue to cause disease outbreaks in poultry and wild birds...
  18. Rasamoelina Andriamanivo H, Lancelot R, Maminiaina O, Rakotondrafara T, Jourdan M, Renard J, et al. Risk factors for avian influenza and Newcastle disease in smallholder farming systems, Madagascar highlands. Prev Vet Med. 2012;104:114-24 pubmed publisher
    b>Newcastle disease (ND) and avian influenza (AI) are issues of interest to avian producers in Madagascar...
  19. Estevez C, King D, Luo M, Yu Q. A single amino acid substitution in the haemagglutinin-neuraminidase protein of Newcastle disease virus results in increased fusion promotion and decreased neuraminidase activities without changes in virus pathotype. J Gen Virol. 2011;92:544-51 pubmed publisher
    Attachment of Newcastle disease virus (NDV) to the host cell is mediated by the haemagglutinin-neuraminidase (HN), a multifunctional protein that has receptor recognition, neuraminidase (NA) and fusion promotion activities...
  20. Kim B, Lee D, Kim M, Jang J, Lee Y, Park J, et al. Exchange of Newcastle disease viruses in Korea: the relatedness of isolates between wild birds, live bird markets, poultry farms and neighboring countries. Infect Genet Evol. 2012;12:478-82 pubmed publisher
    b>Newcastle disease virus (NDV) has a worldwide distribution and is often carried by wild ducks, which may represent one of the natural reservoirs...
  21. Ababneh M, Dalab A, Alsaad S, Al Zghoul M, Al Natour M. Molecular characterization of a recent Newcastle disease virus outbreak in Jordan. Res Vet Sci. 2012;93:1512-4 pubmed publisher
    b>Newcastle disease (ND) is a highly contagious viral disease and is a continuous threat to the poultry industry worldwide...
  22. Steel J, Burmakina S, Thomas C, Spackman E, Garcia Sastre A, Swayne D, et al. A combination in-ovo vaccine for avian influenza virus and Newcastle disease virus. Vaccine. 2008;26:522-31 pubmed
    The protection of poultry from H5N1 highly pathogenic avian influenza A (HPAI) and Newcastle disease virus (NDV) can be achieved through vaccination, as part of a broader disease control strategy...
  23. Ahmad Raus R, Ali A, Tan W, Salleh H, Eshaghi M, Yusoff K. Localization of the antigenic sites of newcastle disease virus nucleocapsid using a panel of monoclonal antibodies. Res Vet Sci. 2009;86:174-82 pubmed publisher
    A panel of six monoclonal antibodies (mAbs) against the nucleocapsid (NP) protein of Newcastle disease virus (NDV) was produced by immunization of Balb/c mice with purified recombinant NP protein...
  24. Liu D, Niu Z. Cloning of a gene fragment encoding chicken complement component C3d with expression and immunogenicity of Newcastle disease virus F gene-C3d fusion protein. Avian Pathol. 2008;37:477-85 pubmed publisher
    ..were engineered to contain two, four and six copies of the chC3d-P29 coding gene linked to the F gene of Newcastle disease virus, an economically important pathogen of chicken that is classified as a list A contagious disease of ..
  25. Fuller C, Collins M, Alexander D. Development of a real-time reverse-transcription PCR for the detection and simultaneous pathotyping of Newcastle disease virus isolates using a novel probe. Arch Virol. 2009;154:929-37 pubmed publisher
    ..PCR (RRT-PCR) was developed to detect and pathotype avian paramyxovirus type 1 (APMV-1), also known as Newcastle disease virus (NDV), which had been grown in embryonated fowls' eggs...
  26. Lindh E, Huovilainen A, Rätti O, Ek Kommonen C, Sironen T, Huhtamo E, et al. Orthomyxo-, paramyxo- and flavivirus infections in wild waterfowl in Finland. Virol J. 2008;5:35 pubmed publisher
  27. Han G, He C, Ding N, Ma L. Identification of a natural multi-recombinant of Newcastle disease virus. Virology. 2008;371:54-60 pubmed
    b>Newcastle disease (ND), caused by ND virus (NDV), is one of the most serious illnesses of birds, particularly chickens, and has been one of the major causes of economic losses in the poultry industry...
  28. Talebi A, Amirzadeh B, Mokhtari B, Gahri H. Effects of a multi-strain probiotic (PrimaLac) on performance and antibody responses to Newcastle disease virus and infectious bursal disease virus vaccination in broiler chickens. Avian Pathol. 2008;37:509-12 pubmed publisher
    ..and Bifidobacterium bifidium) was investigated on performance and immune responses to vaccination against Newcastle disease and infectious bursal disease in broiler chickens. Use of PrimaLac significantly (P<0...
  29. Goff P, Gao Q, Palese P. A majority of infectious Newcastle disease virus particles contain a single genome, while a minority contain multiple genomes. J Virol. 2012;86:10852-6 pubmed publisher
    ..A quantitative approach to paramyxovirus packaging revealed a majority of infectious Newcastle disease viruses contain one functional genome...
  30. Lung O, Beeston A, Ohene Adjei S, Pasick J, Hodko D, Hughes K, et al. Electronic microarray assays for avian influenza and Newcastle disease virus. J Virol Methods. 2012;185:244-53 pubmed publisher
    ..virus (AIV) is currently classified into 16 H (hemagglutinin) and 9 N (neuraminidase) subtypes, whereas Newcastle disease virus (NDV) strains differ in virulence and are broadly classified into high and low pathogenicity types...
  31. Wakamatsu N, King D, Seal B, Peeters B, Brown C. The effect on pathogenesis of Newcastle disease virus LaSota strain from a mutation of the fusion cleavage site to a virulent sequence. Avian Dis. 2006;50:483-8 pubmed
    The principal molecular determinant of virulence of Newcastle disease virus (NDV) is the amino acid sequence at the fusion cleavage activation site...
  32. Qin Z, Xu H, Ouyang W, Wang Y, Wang L, Yuan X, et al. [Correlation of the neutralization index in chicken embryo with the homologies of F and HN gene of different Newcastle-disease isolates]. Wei Sheng Wu Xue Bao. 2008;48:226-33 pubmed
    ..05, r = 0.20 or 0.19) with the F gene, and non-correlated with 374 nt segment. This implied that the genetic mutations of HN resulted in antigenic variations of these viruses and the search for new vaccines would be necessary...
  33. Sarfati Mizrahi D, Lozano Dubernard B, Soto Priante E, Castro Peralta F, Flores Castro R, Loza Rubio E, et al. Protective dose of a recombinant Newcastle disease LaSota-avian influenza virus H5 vaccine against H5N2 highly pathogenic avian influenza virus and velogenic viscerotropic Newcastle disease virus in broilers with high maternal antibody levels. Avian Dis. 2010;54:239-41 pubmed
    The protective dose of a live recombinant LaSota Newcastle disease virus (NDV)-avian influenza H5 vaccine (rNDV-LS/AI-H5) was determined in broiler chickens with high levels of maternal antibodies against NDV and avian influenza virus (..
  34. Kumar S, Nayak B, Collins P, Samal S. Evaluation of the Newcastle disease virus F and HN proteins in protective immunity by using a recombinant avian paramyxovirus type 3 vector in chickens. J Virol. 2011;85:6521-34 pubmed publisher
    b>Newcastle disease virus (NDV) belongs to serotype 1 of the avian paramyxoviruses (APMV-1) and causes severe disease in chickens. Current live attenuated NDV vaccines are not fully satisfactory...
  35. Luo C, Qu H, Ma J, Wang J, Li C, Yang C, et al. Genome-wide association study of antibody response to Newcastle disease virus in chicken. BMC Genet. 2013;14:42 pubmed publisher
    Since the first outbreak in Indonesia in 1926, Newcastle disease has become one of the most common and contagious bird diseases throughout the world...
  36. Yan Y, Samal S. Role of intergenic sequences in newcastle disease virus RNA transcription and pathogenesis. J Virol. 2008;82:1323-31 pubmed
    b>Newcastle disease virus (NDV), a member of the family Paramyxoviridae, has a nonsegmented negative-sense RNA genome consisting of six genes (3'-NP-P-M-F-HN-L-5')...
  37. Hassan W, Khair S, Mochotlhoane B, Abolnik C. Newcastle disease outbreaks in the Sudan from 2003 to 2006 were caused by viruses of genotype 5d. Virus Genes. 2010;40:106-10 pubmed publisher
    b>Newcastle disease (ND) is a serious neurological and respiratory disease of poultry that affects all types of birds but has traditionally not caused symptoms in wild aquatic birds, the natural hosts...
  38. Rauw F, Gardin Y, Palya V, Anbari S, Gonze M, Lemaire S, et al. The positive adjuvant effect of chitosan on antigen-specific cell-mediated immunity after chickens vaccination with live Newcastle disease vaccine. Vet Immunol Immunopathol. 2010;134:249-58 pubmed publisher
    ..this aim, we explored its potential as adjuvant given by oculo-nasal route to one-day-old chickens with live Newcastle disease (ND) vaccine...
  39. El Zowalaty M, Chander Y, Redig P, Abd El Latif H, El Sayed M, Goyal S. Selective isolation of Avian influenza virus (AIV) from cloacal samples containing AIV and Newcastle disease virus. J Vet Diagn Invest. 2011;23:330-2 pubmed
    ..In addition to AIV, waterfowl are often coinfected with other viruses, such as the paramyxoviruses, of which Newcastle disease virus (NDV) is of particular importance because of the highly virulent nature of certain strains of this ..
  40. Wilden H, Schirrmacher V, Fournier P. Important role of interferon regulatory factor (IRF)-3 in the interferon response of mouse macrophages upon infection by Newcastle disease virus. Int J Oncol. 2011;39:493-504 pubmed publisher
    b>Newcastle disease virus (NDV) is an interesting agent for activating innate immune activity in macrophages including secretion of TNF-? and IFN-?, upregulation of TRAIL and activation of NF-?B and iNOS...
  41. Munir M, Zohari S, Abbas M, Berg M. Sequencing and analysis of the complete genome of Newcastle disease virus isolated from a commercial poultry farm in 2010. Arch Virol. 2012;157:765-8 pubmed publisher
    b>Newcastle disease virus (NDV) infects wild and domestic birds but causes contagious and lethal disease in domestic poultry. ND is currently endemic in Pakistan, but no complete genome sequence of a Pakistani NDV isolate has been reported...
  42. Dortmans J, Peeters B, Koch G. Newcastle disease virus outbreaks: vaccine mismatch or inadequate application?. Vet Microbiol. 2012;160:17-22 pubmed publisher
    b>Newcastle disease (ND) is one of the most important diseases of poultry, and may cause devastating losses in the poultry industry worldwide. Its causative agent is Newcastle disease virus (NDV), also known as avian paramyxovirus type 1...
  43. Diel D, da Silva L, Liu H, Wang Z, Miller P, Afonso C. Genetic diversity of avian paramyxovirus type 1: proposal for a unified nomenclature and classification system of Newcastle disease virus genotypes. Infect Genet Evol. 2012;12:1770-9 pubmed publisher
    The avian paramyxovirus type 1 (APMV-1), or Newcastle disease virus (NDV), comprise a diverse group of viruses with a single-stranded, negative-sense RNA genome...
  44. Umali D, Ito H, Suzuki T, Shirota K, Katoh H, Ito T. Molecular epidemiology of Newcastle disease virus isolates from vaccinated commercial poultry farms in non-epidemic areas of Japan. Virol J. 2013;10:330 pubmed publisher
    b>Newcastle Disease (ND) is a highly contagious and economically devastating disease of poultry. At present, limited molecular epidemiological data are available regarding the causes of ND outbreaks in vaccinated commercial poultry farms...
  45. Aldous E, Alexander D. Newcastle disease in pheasants (Phasianus colchicus): a review. Vet J. 2008;175:181-5 pubmed
    b>Newcastle disease (ND) is regarded throughout the world as one of the most important diseases of poultry, not only due to the serious disease and high flock mortality that may result from some ND virus (NDV) infections, but also through ..
  46. Tan L, Xu H, Wang Y, Qin Z, Sun L, Liu W, et al. Molecular characterization of three new virulent Newcastle disease virus variants isolated in China. J Clin Microbiol. 2008;46:750-3 pubmed
    Three cases of Newcastle disease virus (NDV) found in nature had the lentogenic motif (112)G-R-Q-G-R-L(117) in their fusion protein cleavage sites...
  47. Ezema W, Okoye J, Nwanta J. LaSota vaccination may not protect against the lesions of velogenic Newcastle disease in chickens. Trop Anim Health Prod. 2009;41:477-84 pubmed publisher
    ..birds were inoculated intramuscularly with VGF-1, which is a local Nigerian strain of velogenic Newcastle disease virus (VNDV). Immunized birds did not show any clinical signs except significant loss (p < 0...
  48. Jafari R, Jalali M, Ghorbanpoor M, Saraei S. Effect of dietary garlic on immune response of broiler chicks to live Newcastle Disease vaccine. Pak J Biol Sci. 2008;11:1848-51 pubmed
    ..was designed to determine the effect of garlic powder on humoral immune response of broilers against NDV (Newcastle Disease Virus) vaccine...
  49. Tseng L, Liang H, Deng M, Lee K, Pan R, Yang J, et al. The influence of liposomal adjuvant on intranasal vaccination of chickens against Newcastle disease. Vet J. 2010;185:204-10 pubmed publisher
    ..PS-Lip), and stearylamine-liposomes (SA-Lip) was compared with virus alone using inactivated Newcastle disease virus (NDV) as a model antigen...
  50. Cattoli G, Fusaro A, Monne I, Molia S, Le Menach A, Maregeya B, et al. Emergence of a new genetic lineage of Newcastle disease virus in West and Central Africa--implications for diagnosis and control. Vet Microbiol. 2010;142:168-76 pubmed publisher
    b>Newcastle disease (ND) is an OIE listed disease caused by virulent avian paramyxovirus type 1 (APMV-1) strains, which affect many species of birds and may cause severe economic losses in the poultry sector...
  51. Sawant P, Verma P, Subudhi P, Chaturvedi U, Singh M, Kumar R, et al. Immunomodulation of bivalent Newcastle disease DNA vaccine induced immune response by co-delivery of chicken IFN-? and IL-4 genes. Vet Immunol Immunopathol. 2011;144:36-44 pubmed publisher
    ..whether co-administration of interferon-? (IFN-?) and/or interleukin-4 (IL-4) gene along with a bivalent Newcastle disease (ND) DNA vaccine construct could modulate the immune response to the DNA vaccine in chickens...
  52. Miller P, King D, Afonso C, Suarez D. Antigenic differences among Newcastle disease virus strains of different genotypes used in vaccine formulation affect viral shedding after a virulent challenge. Vaccine. 2007;25:7238-46 pubmed
    Strains of Newcastle disease virus (NDV) can be separated into genotypes based on genome differences even though they are antigenically considered to be of a single serotype...
  53. Miller P, Estevez C, Yu Q, Suarez D, King D. Comparison of viral shedding following vaccination with inactivated and live Newcastle disease vaccines formulated with wild-type and recombinant viruses. Avian Dis. 2009;53:39-49 pubmed
    Virulent Newcastle disease virus isolates from the 1971 and 2002 U.S. outbreaks are of the same serotype but a different genotype than current vaccine strains...
  54. Miller P, Decanini E, Afonso C. Newcastle disease: evolution of genotypes and the related diagnostic challenges. Infect Genet Evol. 2010;10:26-35 pubmed publisher
    Since the discovery of Newcastle disease virus (NDV) in 1926, nine genotypes of class I viruses and ten of class II have been identified, representing a diverse and continually evolving group of viruses...
  55. Dortmans J, Rottier P, Koch G, Peeters B. The viral replication complex is associated with the virulence of Newcastle disease virus. J Virol. 2010;84:10113-20 pubmed publisher
    Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the ..
  56. Susta L, Miller P, Afonso C, Brown C. Clinicopathological characterization in poultry of three strains of Newcastle disease virus isolated from recent outbreaks. Vet Pathol. 2011;48:349-60 pubmed publisher
    b>Newcastle disease is a severe threat to the poultry industry and is caused by Newcastle disease virus, a member of the genus Avulavirus, family Paramyxoviridae...
  57. Maminiaina O, Gil P, Briand F, Albina E, Keita D, Andriamanivo H, et al. Newcastle disease virus in Madagascar: identification of an original genotype possibly deriving from a died out ancestor of genotype IV. PLoS ONE. 2010;5:e13987 pubmed publisher
    In Madagascar, Newcastle disease (ND) has become enzootic after the first documented epizootics in 1946, with recurrent annual outbreaks causing mortality up to 40%...
  58. Guo L, Wang D, Hu Y, Zhao X, Wang Y, Yang S, et al. Adjuvanticity of compound polysaccharides on chickens against Newcastle disease and avian influenza vaccine. Int J Biol Macromol. 2012;50:512-7 pubmed publisher
    ..Therefore, the adjuvanticities of APS-sEPS on Newcastle disease (ND) and avian influenza (AI) vaccine were further validated...
  59. Yacoub A, Leijon M, McMenamy M, Ullman K, McKillen J, Allan G, et al. Development of a novel real-time PCR-based strategy for simple and rapid molecular pathotyping of Newcastle disease virus. Arch Virol. 2012;157:833-44 pubmed publisher
    ..applied to simultaneously detect and to discriminate low-pathogenic lentogenic and virulent meso/velogenic Newcastle disease virus (NDV). The pathotyping is achieved by a three-step semi-nested PCR...
  60. Munir K, Muneer M, Tiwari A, Chaudhry R, Muruganandan S. Effects of polyether ionophores on the protective immune responses of broiler chickens against Angara disease and Newcastle disease viruses. Vet Res Commun. 2007;31:909-29 pubmed
    Immunization against Angara disease virus (ADV), a serotype 4 avian adenovirus, and Newcastle disease virus (NDV), an avian paramyxovirus serotype 1, is the mainstay of a broiler vaccination programme, while polyether ionophores usually ..
  61. Sun H, Wang Y, Tong G, Zhang P, Miao D, Zhi H, et al. Protection of chickens from Newcastle disease and infectious laryngotracheitis with a recombinant fowlpox virus co-expressing the F, HN genes of Newcastle disease virus and gB gene of infectious laryngotracheitis virus. Avian Dis. 2008;52:111-7 pubmed
    A recombinant fowlpox virus (rFPV) coexpressing the Newcastle disease virus (NDV) fusion and hemagglutinin-neuraminidase genes and infectious laryngothracheitis virus (ILTV) glycoprotein B gene was constructed...
  62. Tan S, Ideris A, Omar A, Yusoff K, Hair Bejo M. Detection and differentiation of velogenic and lentogenic Newcastle disease viruses using SYBR Green I real-time PCR with nucleocapsid gene-specific primers. J Virol Methods. 2009;160:149-56 pubmed publisher
    SYBR Green I real-time PCR was developed for detection and differentiation of Newcastle disease virus (NDV)...
  63. Khattar S, Yan Y, Panda A, Collins P, Samal S. A Y526Q mutation in the Newcastle disease virus HN protein reduces its functional activities and attenuates virus replication and pathogenicity. J Virol. 2009;83:7779-82 pubmed publisher
    The hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is a multifunctional protein that plays a crucial role in virus infectivity...
  64. Zoth S, Gómez E, Carballeda J, Carrillo E, Berinstein A. Expression of a secreted version of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus: its evaluation as a diagnostic reagent. J Vet Diagn Invest. 2011;23:519-23 pubmed publisher
    The hemagglutinin-neuraminidase (HN) glycoprotein of Newcastle disease virus (NDV) constitutes, together with the fusion glycoprotein, the main surface antigen of this avian pathogen, which causes a highly contagious disease, relevant ..
  65. Hu Z, Hu S, Meng C, Wang X, Zhu J, Liu X. Generation of a genotype VII Newcastle disease virus vaccine candidate with high yield in embryonated chicken eggs. Avian Dis. 2011;55:391-7 pubmed
    To generate a genotype VII Newcastle disease virus (NDV) vaccine with high yield in embryonated chicken eggs, we selected genotype VII NDV strain JS5/05, which possesses a high virus titer in embryos as the parental virus...
  66. Sharma B, Pokhriyal M, Rai G, Saxena M, Ratta B, Chaurasia M, et al. Isolation of Newcastle disease virus from a non-avian host (sheep) and its implications. Arch Virol. 2012;157:1565-7 pubmed publisher
    b>Newcastle disease virus (NDV) is an avian virus that has not been isolated from naturally infected non-avian and non-human hosts except for one report in which it was isolated from cattle in 1952...
  67. Sun Y, Ding N, Ding S, Yu S, Meng C, Chen H, et al. Goose RIG-I functions in innate immunity against Newcastle disease virus infections. Mol Immunol. 2013;53:321-7 pubmed publisher
    ..retinoic acid-inducible gene I (RIG-I) is a chief antiviral gene sensing viral RNA molecules including Newcastle disease virus (NDV). In this study, goose RIG-I gene (gRIG-I) was identified...
  68. Kim S, Wanasen N, Paldurai A, Xiao S, Collins P, Samal S. Newcastle disease virus fusion protein is the major contributor to protective immunity of genotype-matched vaccine. PLoS ONE. 2013;8:e74022 pubmed publisher
    Virulent strains of Newcastle disease virus (NDV) can cause devastating disease in chickens worldwide. Although the current vaccines are substantially effective, they do not completely prevent infection, virus shedding and disease...
  69. Zhao K, Zhang Y, Zhang X, Li W, Shi C, Guo C, et al. Preparation and efficacy of Newcastle disease virus DNA vaccine encapsulated in chitosan nanoparticles. Int J Nanomedicine. 2014;9:389-402 pubmed publisher
    Optimal preparation conditions of Newcastle disease virus (NDV) F gene deoxyribonucleic acid (DNA) vaccine encapsulated in chitosan nanoparticles (pFNDV-CS-NPs) were determined...
  70. Zanetti F, Berinstein A, Carrillo E. Effect of host selective pressure on Newcastle disease virus virulence. Microb Pathog. 2008;44:135-40 pubmed
    b>Newcastle disease virus (NDV) causes an economically important disease that can vary from clinically inapparent to highly virulent forms. Generally, NDV strains isolated from wild birds are non-pathogenic for chicken...
  71. Qin Z, Tan L, Xu H, Ma B, Wang Y, Yuan X, et al. Pathotypical characterization and molecular epidemiology of Newcastle disease virus isolates from different hosts in China from 1996 to 2005. J Clin Microbiol. 2008;46:601-11 pubmed
    Thirty Newcastle disease virus (NDV) strains isolated from outbreaks in China during 1996 to 2005 were characterized pathotypically and genotypically. All strains except one were velogenic...
  72. Bwala D, Abolnik C, Van Wyk A, Cornelius E, Bisschop S. Efficacy of a genotype 2 Newcastle disease vaccine (Avinew) against challenge with highly virulent genotypes 5d and 3d. J S Afr Vet Assoc. 2009;80:174-8 pubmed
    Since 2002, following its introduction, the lineage 5d Newcastle disease virus (so-called Goose paramyxovirus - GPMV) strain has caused numerous disease outbreaks among commercial and backyard poultry in South Africa, raising questions ..
  73. Zhang L, Pan Z, Geng S, Chen X, Hu S, Liu H, et al. Sensitive, semi-nested RT-PCR amplification of fusion gene sequences for the rapid detection and differentiation of Newcastle disease virus. Res Vet Sci. 2010;89:282-9 pubmed publisher
    ..and specific semi-nested RT-PCR was developed to detect and differentiate virulent and avirulent strains of Newcastle disease virus (NDV)...
  74. Wambura P, Kataga S. Putative protective antibody response following oral vaccination of multi-age free ranging helmeted guinea fowls (Numida meleagris) with Newcastle disease virus strain I-2 coated on oiled rice. Trop Anim Health Prod. 2011;43:99-102 pubmed publisher
    On-farm study was conducted to determine the efficacy of thermostable Newcastle disease (ND) strain I-2 vaccine coated on oiled rice following oral vaccination of multi-age free ranging helmeted guinea fowls...
  75. Cattoli G, Susta L, Terregino C, Brown C. Newcastle disease: a review of field recognition and current methods of laboratory detection. J Vet Diagn Invest. 2011;23:637-56 pubmed publisher
    b>Newcastle disease (ND) remains a constant threat to the poultry industry and is a limiting disease for poultry producers worldwide...
  76. Kumar R, Tiwari A, Chaturvedi U, Kumar G, Sahoo A, Rajmani R, et al. Velogenic newcastle disease virus as an oncolytic virotherapeutics: in vitro characterization. Appl Biochem Biotechnol. 2012;167:2005-22 pubmed publisher
    ..Oncolytic virotherapy seems to be a promising nonconventional way to treat cancers. Newcastle disease virus (NDV), a poultry virus, is nonpathogenic to human and domestic animals and has a long history of being ..
  77. Lindh E, Ek Kommonen C, Väänänen V, Alasaari J, Vaheri A, Vapalahti O, et al. Molecular epidemiology of outbreak-associated and wild-waterfowl-derived newcastle disease virus strains in Finland, including a novel class I genotype. J Clin Microbiol. 2012;50:3664-73 pubmed publisher
    b>Newcastle disease (ND) is a highly contagious, severe disease of poultry caused by pathogenic strains of Newcastle disease virus (NDV; or avian paramyxovirus-1)...
  78. Snoeck C, Ducatez M, Owoade A, Faleke O, Alkali B, Tahita M, et al. Newcastle disease virus in West Africa: new virulent strains identified in non-commercial farms. Arch Virol. 2009;154:47-54 pubmed publisher
    Forty-four Newcastle disease virus (NDV) strains, obtained between 2002 and 2007 from different poultry species in Nigeria, Niger, Burkina Faso and Cameroon, were phylogenetically analysed based on partial F sequences...
  79. Hu S, Ma H, Wu Y, Liu W, Wang X, Liu Y, et al. A vaccine candidate of attenuated genotype VII Newcastle disease virus generated by reverse genetics. Vaccine. 2009;27:904-10 pubmed publisher
    Genotype VII Newcastle disease virus (NDV) has been documented as the predominant epidemic genotype in China and some other Asian countries since 1990s...
  80. Tseng L, Chiou C, Chen C, Deng M, Chung T, Huang Y, et al. Effect of lipopolysaccharide on intranasal administration of liposomal Newcastle disease virus vaccine to SPF chickens. Vet Immunol Immunopathol. 2009;131:285-9 pubmed publisher
    In order to potentiate the low immunogenicity of the inactivated Newcastle disease virus immunized into chickens by mucosal route, liposomes as a drug delivery system and LPS (lipopolysaccharide) as an immuno-stimulator were evaluated...
  81. Gopinath V, Raj G, Raja A, Kumanan K, Elankumaran S. Rapid detection of Newcastle disease virus replication in embryonated chicken eggs using quantitative real time polymerase chain reaction. J Virol Methods. 2011;171:98-101 pubmed publisher
    b>Newcastle disease virus (NDV), an avian paramyxovirus, is an economically important disease of poultry globally. Rapid methods to detect and differentiate the virus are important to curtail the spread of this virus...
  82. Yin Y, Cortey M, Zhang Y, Cui S, Dolz R, Wang J, et al. Molecular characterization of Newcastle disease viruses in Ostriches (Struthio camelus L.): further evidences of recombination within avian paramyxovirus type 1. Vet Microbiol. 2011;149:324-9 pubmed publisher
    b>Newcastle disease virus (NDV) strains isolated from ostriches have been genotyped for the first time by partial sequencing of the F gene to determine the epidemiologic role that this species can play within ND outbreaks...
  83. Hu H, Roth J, Estevez C, Zsak L, Liu B, Yu Q. Generation and evaluation of a recombinant Newcastle disease virus expressing the glycoprotein (G) of avian metapneumovirus subgroup C as a bivalent vaccine in turkeys. Vaccine. 2011;29:8624-33 pubmed publisher
    Virulent strains of Newcastle disease virus (NDV) and avian metapneumovirus (aMPV) can cause serious respiratory diseases in poultry...
  84. Spackman E, Pedersen J, McKinley E, Gelb J. Optimal specimen collection and transport methods for the detection of avian influenza virus and Newcastle disease virus. BMC Vet Res. 2013;9:35 pubmed publisher
    Active and passive surveillance for avian influenza virus (AIV) and Newcastle disease virus (NDV) is widespread in commercial poultry worldwide, therefore optimization of sample collection and transport would be valuable to achieve the ..
  85. Jeon W, Lee E, Lee Y, Jeong O, Kim Y, Kwon J, et al. Protective efficacy of commercial inactivated Newcastle disease virus vaccines in chickens against a recent Korean epizootic strain. J Vet Sci. 2008;9:295-300 pubmed
    Despite the intensive vaccination policy that has been put in place to control Newcastle disease virus (NDV), the recent emergence of NDV genotype VII strains in Korea has led to significant economic losses in the poultry industry...
  86. Guo Z, Hu Y, Wang D, Ma X, Zhao X, Zhao B, et al. Sulfated modification can enhance the adjuvanticity of lentinan and improve the immune effect of ND vaccine. Vaccine. 2009;27:660-5 pubmed publisher
    The purpose of this research is to study the effect of sulfated lentinan (sLNT) on immune effect of Newcastle disease (ND) vaccine...
  87. Khalifeh M, Amawi M, Abu Basha E, Yonis I. Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. Poult Sci. 2009;88:2118-24 pubmed publisher
    ..The effect of tilmicosin, florfenicol, or enrofloxacin on humoral and cell-mediated immune response induced by Newcastle disease (ND) vaccination was evaluated in 20-wk-old specific-pathogen-free layer chickens...
  88. Chong Y, Padhi A, Hudson P, Poss M. The effect of vaccination on the evolution and population dynamics of avian paramyxovirus-1. PLoS Pathog. 2010;6:e1000872 pubmed publisher
    b>Newcastle Disease Virus (NDV) is a pathogenic strain of avian paramyxovirus (aPMV-1) that is among the most serious of disease threats to the poultry industry worldwide...
  89. Dortmans J, Koch G, Rottier P, Peeters B. Virulence of Newcastle disease virus: what is known so far?. Vet Res. 2011;42:122 pubmed publisher
    In the last decade many studies have been performed on the virulence of Newcastle disease virus (NDV)...
  90. Munir M, Abbas M, Khan M, Zohari S, Berg M. Genomic and biological characterization of a velogenic Newcastle disease virus isolated from a healthy backyard poultry flock in 2010. Virol J. 2012;9:46 pubmed publisher
    b>Newcastle disease virus (NDV) causes severe and economically important disease in poultry around the globe. None of NDV strains in Pakistan have been completely characterized and the role of rural poultry in harbouring NDV is unclear...