Summary: A preconceived judgment made without adequate evidence and not easily alterable by presentation of contrary evidence.

Top Publications

  1. pmc Stigma in the HIV/AIDS epidemic: a review of the literature and recommendations for the way forward
    Anish P Mahajan
    UCLA Program in Global Health, University of California, Los Angeles, California 90024, USA
    AIDS 22:S67-79. 2008
  2. ncbi HIV and AIDS-related stigma and discrimination: a conceptual framework and implications for action
    Richard Parker
    Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    Soc Sci Med 57:13-24. 2003
  3. pmc Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence
    Ilan H Meyer
    Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Psychol Bull 129:674-97. 2003
  4. ncbi Bias, discrimination, and obesity
    R Puhl
    Department of Psychology, Yale University, New Haven, Connecticut 06520-8205, USA
    Obes Res 9:788-805. 2001
  5. pmc The utilization of testing and counseling for HIV: a review of the social and behavioral evidence
    Carla Makhlouf Obermeyer
    Department of HIV, World Health Organization, Geneva, Switzerland
    Am J Public Health 97:1762-74. 2007
  6. pmc HIV testing attitudes, AIDS stigma, and voluntary HIV counselling and testing in a black township in Cape Town, South Africa
    S C Kalichman
    Department of Psychology, University of Connecticut, Storrs, CT 06269, USA
    Sex Transm Infect 79:442-7. 2003
  7. pmc Discrimination and racial disparities in health: evidence and needed research
    David R Williams
    Department of Society, Human Development and Health, Harvard School of Public Health, 677 Huntington Avenue, 6th Floor, Boston, MA 02115, USA
    J Behav Med 32:20-47. 2009
  8. ncbi A systematic review of empirical research on self-reported racism and health
    Yin Paradies
    Centre for Health and Society, University of Melbourne, Australia
    Int J Epidemiol 35:888-901. 2006
  9. pmc Perceived discrimination and health: a meta-analytic review
    Elizabeth A Pascoe
    Department of Psychology and Neuroscience, Duke University, Durham, NC 27708 0086, USA
    Psychol Bull 135:531-54. 2009
  10. ncbi Measuring HIV stigma: existing knowledge and gaps
    Laura C Nyblade
    International Center for Research on Women ICRW, Washington, DC 20036, USA
    Psychol Health Med 11:335-45. 2006

Detail Information

Publications354 found, 100 shown here

  1. pmc Stigma in the HIV/AIDS epidemic: a review of the literature and recommendations for the way forward
    Anish P Mahajan
    UCLA Program in Global Health, University of California, Los Angeles, California 90024, USA
    AIDS 22:S67-79. 2008
    ..Based on the literature, we conclude by offering a set of recommendations that may represent important next steps in a multifaceted response to stigma in the HIV/AIDS epidemic...
  2. ncbi HIV and AIDS-related stigma and discrimination: a conceptual framework and implications for action
    Richard Parker
    Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    Soc Sci Med 57:13-24. 2003
  3. pmc Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence
    Ilan H Meyer
    Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Psychol Bull 129:674-97. 2003
    ..for understanding this excess in prevalence of disorder in terms of minority stress--explaining that stigma, prejudice, and discrimination create a hostile and stressful social environment that causes mental health problems...
  4. ncbi Bias, discrimination, and obesity
    R Puhl
    Department of Psychology, Yale University, New Haven, Connecticut 06520-8205, USA
    Obes Res 9:788-805. 2001
    ..Given the vast numbers of people potentially affected, it is important to consider the research-related, educational, and social policy implications of these findings...
  5. pmc The utilization of testing and counseling for HIV: a review of the social and behavioral evidence
    Carla Makhlouf Obermeyer
    Department of HIV, World Health Organization, Geneva, Switzerland
    Am J Public Health 97:1762-74. 2007
    ..We demonstrate that social factors have a considerable impact on testing, show that the services linked to testing are key determinants of utilization, and consider the implications of these findings for HIV testing programs...
  6. pmc HIV testing attitudes, AIDS stigma, and voluntary HIV counselling and testing in a black township in Cape Town, South Africa
    S C Kalichman
    Department of Psychology, University of Connecticut, Storrs, CT 06269, USA
    Sex Transm Infect 79:442-7. 2003
    ..This study examined the relation between HIV testing history, attitudes towards testing, and AIDS stigmas...
  7. pmc Discrimination and racial disparities in health: evidence and needed research
    David R Williams
    Department of Society, Human Development and Health, Harvard School of Public Health, 677 Huntington Avenue, 6th Floor, Boston, MA 02115, USA
    J Behav Med 32:20-47. 2009
  8. ncbi A systematic review of empirical research on self-reported racism and health
    Yin Paradies
    Centre for Health and Society, University of Melbourne, Australia
    Int J Epidemiol 35:888-901. 2006
    ..Ensuring the quality of studies in this field will allow future research to reveal the complex role that racism plays as a determinant of population health...
  9. pmc Perceived discrimination and health: a meta-analytic review
    Elizabeth A Pascoe
    Department of Psychology and Neuroscience, Duke University, Durham, NC 27708 0086, USA
    Psychol Bull 135:531-54. 2009
    ..These findings suggest potential pathways linking perceived discrimination to negative health outcomes...
  10. ncbi Measuring HIV stigma: existing knowledge and gaps
    Laura C Nyblade
    International Center for Research on Women ICRW, Washington, DC 20036, USA
    Psychol Health Med 11:335-45. 2006
  11. ncbi Changes in perceived weight discrimination among Americans, 1995-1996 through 2004-2006
    Tatiana Andreyeva
    Rudd Center for Food Policy and Obesity, Yale University, New Haven, Connecticut, USA
    Obesity (Silver Spring) 16:1129-34. 2008
    ..This study examined the trends in perceived weight/height discrimination among a nationally representative sample of adults aged 35-74 years, comparing experiences of discrimination based on race, age, and gender...
  12. ncbi Internalized stigma of mental illness: psychometric properties of a new measure
    Jennifer Boyd Ritsher
    Center for Health Care Evaluation, US Department of Veterans Affairs and Stanford University, School of Medicine, Menlo Park, CA, USA
    Psychiatry Res 121:31-49. 2003
    ..Having a validated measure of internalized stigma may encourage clinicians to include stigma reduction as a verifiable treatment goal in addition to symptom reduction...
  13. pmc Understanding and addressing AIDS-related stigma: from anthropological theory to clinical practice in Haiti
    Arachu Castro
    Program in Infectious Disease and Social Change, Department of Social Medicine, Harvard Medical School, 641 Huntington Ave, Boston, MA 02115, USA
    Am J Public Health 95:53-9. 2005
    ..Rather than stigma, logistic and economic barriers determine who will access such services. Implications for scale-up of integrated AIDS prevention and care are explored...
  14. pmc A comparison of HIV stigma and discrimination in five international sites: the influence of care and treatment resources in high prevalence settings
    Suzanne Maman
    Department of Health Behavior and Health Education, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Soc Sci Med 68:2271-8. 2009
    ..We need effective strategies to reduce HIV stigma as treatment and care resources are scaled up in the settings that are most heavily impacted by the HIV epidemic...
  15. ncbi Reducing anti-fat prejudice in preservice health students: a randomized trial
    Kerry S O'Brien
    School of Psychological Sciences, University of Manchester, Manchester, UK
    Obesity (Silver Spring) 18:2138-44. 2010
    ..There is no evidence for effective obesity prejudice reduction techniques in health professionals...
  16. pmc HIV-related stigma and knowledge in the United States: prevalence and trends, 1991-1999
    Gregory M Herek
    Department of Psychology, University of California at Davis, 1 Shields Avenue, Davis, CA 95616 8686, USA
    Am J Public Health 92:371-7. 2002
    ..This study assessed the prevalence of AIDS stigma and misinformation about HIV transmission in 1997 and 1999 and examined trends in stigma in the United States during the 1990s...
  17. pmc Mental health correlates of perceived discrimination among lesbian, gay, and bisexual adults in the United States
    V M Mays
    Department of Psychology, University of California, Los Angeles 90095 1563, USA
    Am J Public Health 91:1869-76. 2001
    ..Recent studies suggest that lesbians and gay men are at higher risk for stress-sensitive psychiatric disorders than are heterosexual persons. We examined the possible role of perceived discrimination in generating that risk...
  18. ncbi The prevalence, distribution, and mental health correlates of perceived discrimination in the United States
    R C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    J Health Soc Behav 40:208-30. 1999
  19. ncbi Internalized stigma, discrimination, and depression among men and women living with HIV/AIDS in Cape Town, South Africa
    Leickness C Simbayi
    Social Aspects of HIV AIDS and Health, Human Sciences Research Council, P Bag X9182, Cape Town 8000, South Africa
    Soc Sci Med 64:1823-31. 2007
    ..These results indicate an urgent need for social reform to reduce AIDS stigmas and the design of interventions to assist people living with HIV/AIDS to adjust and adapt to the social conditions of AIDS in South Africa...
  20. pmc Racial residential segregation: a fundamental cause of racial disparities in health
    D R Williams
    Department of Sociology and Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI 48106 1248, USA
    Public Health Rep 116:404-16. 2001
    ..The authors conclude that effective efforts to eliminate racial disparities in health must seriously confront segregation and its pervasive consequences...
  21. ncbi Is obesity stigmatizing? Body weight, perceived discrimination, and psychological well-being in the United States
    Deborah Carr
    Department of Sociology, Institute for Health, Health Care Policy, and Aging Research, Rutgers University, 30 College Avenue, New Brunswick, NJ 08901, USA
    J Health Soc Behav 46:244-59. 2005
    ..Our findings offer further support for the pervasive stigma of obesity and the negative implications of stigmatized identities for life chances...
  22. pmc Attitudes of mental health professionals toward people with schizophrenia and major depression
    Carlos Nordt
    Psychiatric University Hospital, Zurich, Switzerland
    Schizophr Bull 32:709-14. 2006
    ..The study concludes that the better knowledge of mental health professionals and their support of individual rights neither entail fewer stereotypes nor enhance the willingness to closely interact with mentally ill people...
  23. ncbi Attitudes and evaluations: a social cognitive neuroscience perspective
    William A Cunningham
    Department of Psychology, Ohio State University, Columbus, Ohio 43210, USA
    Trends Cogn Sci 11:97-104. 2007
    ..This model makes predictions that inform social-cognitive and cognitive-neuroscientific accounts of evaluation...
  24. ncbi When prejudice does not pay: effects of interracial contact on executive function
    Jennifer A Richeson
    Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
    Psychol Sci 14:287-90. 2003
  25. pmc Racial/ethnic discrimination and health: findings from community studies
    David R Williams
    Institute for Social Research, University of Michigan, Ann Arbor 48106, USA
    Am J Public Health 93:200-8. 2003
    ..Research on stress points to important directions for the future assessment of discrimination and the testing of the underlying processes and mechanisms by which discrimination can lead to changes in health...
  26. ncbi Selective gender differences in childhood nutrition and immunization in rural India: the role of siblings
    Rohini P Pande
    International Center for Research on Women, 1717 Massachusetts Avenue, NW, Suite 302, Washington, DC 20036, USA
    Demography 40:395-418. 2003
    ..However, the preference for sons persists, and boys who were born after multiple daughters have the best possible outcomes...
  27. ncbi Weight bias among health professionals specializing in obesity
    Marlene B Schwartz
    Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
    Obes Res 11:1033-9. 2003
    ..To determine the level of anti-fat bias in health professionals specializing in obesity and identify personal characteristics that correlate with both implicit and explicit bias...
  28. pmc Acceptance of and barriers to voluntary HIV counselling and testing among adults in Guizhou province, China
    Wei Ma
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    AIDS 21:S129-35. 2007
  29. ncbi Prejudice and truth about the effect of testosterone on human bargaining behaviour
    C Eisenegger
    Institute for Empirical Research in Economics, Laboratory for Social and Neural Systems Research, University of Zurich, 8006 Zurich, Switzerland
    Nature 463:356-9. 2010
  30. ncbi Gender violence: transgender experiences with violence and discrimination
    E L Lombardi
    UCLA Drug Abuse Research Center, Los Angeles, CA 90025, USA
    J Homosex 42:89-101. 2001
    There is a pervasive pattern of discrimination and prejudice against transgendered people within society...
  31. ncbi England's time to change antistigma campaign: one-year outcomes of service user-rated experiences of discrimination
    Claire Henderson
    Department of Health Service and Population Research, Kings College London, London, United Kingdom SE5
    Psychiatr Serv 63:451-7. 2012
    ..This study evaluated the progress at one year of England's Time to Change (TTC) program, launched in 2009, toward meeting its target to reduce mental health-related stigma and discrimination by 5%...
  32. pmc The association between perceived discrimination and obesity in a population-based multiracial and multiethnic adult sample
    Haslyn E R Hunte
    Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, USA
    Am J Public Health 99:1285-92. 2009
    ..We examined whether perceived chronic discrimination was related to excess body fat accumulation in a random, multiethnic, population-based sample of US adults...
  33. ncbi 'My biggest fear was that people would reject me once they knew my status...': stigma as experienced by patients in an HIV/AIDS clinic in Johannesburg, South Africa
    Leah Gilbert
    Department of Sociology, University of the Witwatersrand, Johannesburg, Wits, South Africa
    Health Soc Care Community 18:139-46. 2010
    ..However, this approach was not shared by many family members, neighbours and employers who held highly stigmatised views...
  34. ncbi Fear of stigmatization as barrier to voluntary HIV counselling and testing in South Africa
    Annemarie E Meiberg
    Maaslricht University, The Netherlands
    East Afr J Public Health 5:49-54. 2008
    ..The objective of this qualitative study was to identify psychosocial correlates of HIV voluntary counselling and testing (VCT), with an emphasis on the association between fear of AIDS-related stigma and willingness to have an HIV test...
  35. pmc The stigma of childhood mental disorders: a conceptual framework
    Abraham Mukolo
    Institute for Global Health, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    J Am Acad Child Adolesc Psychiatry 49:92-103; quiz 198. 2010
    ..To describe the state of the literature on stigma associated with children's mental disorders and highlight gaps in empirical work...
  36. ncbi Stuck in the middle: the many moral challenges with bariatric surgery
    Bjørn Hofmann
    University College of Gjøvik, University of Oslo, Oslo, Norway
    Am J Bioeth 10:3-11. 2010
    ..bariatric surgery, autonomy and informed consent, classification of obesity and selecting assessment endpoints, prejudice among health professionals, intervention in people's life-world, and medicalization of appearance...
  37. ncbi Beyond acculturation: immigration, discrimination, and health research among Mexicans in the United States
    Edna A Viruell-Fuentes
    Harvard School of Public Health, Cambridge, MA, USA
    Soc Sci Med 65:1524-35. 2007
    ..The paper concludes by proposing a conceptual model that locates "othering" processes within a structural framework, and by drawing implications for research on immigrant health and on discrimination and health...
  38. ncbi Race, socioeconomic status, and health. The added effects of racism and discrimination
    D R Williams
    University of Michigan, Department of Sociology and Survey Research Center, Institute for Social Research, Ann Arbor 48106, USA
    Ann N Y Acad Sci 896:173-88. 1999
    ..Residence in poor neighborhoods, racial bias in medical care, the stress of experiences of discrimination and the acceptance of the societal stigma of inferiority can have deleterious consequences for health...
  39. ncbi The fight against stigma: an overview of stigma-reduction strategies and interventions
    Miriam Heijnders
    Royal Tropical Institute KIT, DEV Health, Amsterdam, The Netherlands
    Psychol Health Med 11:353-63. 2006
  40. pmc The relationship between discrimination and substance use disorders among lesbian, gay, and bisexual adults in the United States
    Sean Esteban McCabe
    CorrespSubstance Abuse Research Center and the Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI 48105, USA
    Am J Public Health 100:1946-52. 2010
    ..We examined the associations between 3 types of discrimination (sexual orientation, race, and gender) and substance use disorders in a large national sample in the United States that included 577 lesbian, gay, and bisexual (LGB) adults...
  41. pmc Literacy, social stigma, and HIV medication adherence
    Katherine R Waite
    Health Literacy and Learning Program, Institute for Healthcare Studies, Division of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Gen Intern Med 23:1367-72. 2008
    ..Prior studies have linked limited literacy to poorer HIV medication adherence, although the precise causal pathways of this relationship have only been initially investigated...
  42. ncbi Recent experiences of weight-based stigmatization in a weight loss surgery population: psychological and behavioral correlates
    Kelli E Friedman
    Department of Psychiatry and Behavioral Sciences, Center for Metabolic and Weight Loss Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Obesity (Silver Spring) 16:S69-74. 2008
    ..g., job discrimination, inappropriate comments from physicians) within the past month, psychological functioning, and binge eating among a sample of individuals seeking weight loss surgery...
  43. ncbi Stigma: ignorance, prejudice or discrimination?
    Graham Thornicroft
    Br J Psychiatry 190:192-3. 2007
    The term stigma refers to problems of knowledge (ignorance), attitudes (prejudice) and behaviour (discrimination)...
  44. ncbi Lesbian, gay, bisexual, and transgender (LGBT) physicians' experiences in the workplace
    Michele J Eliason
    Department of Health Education, San Francisco State University, San Francisco, California 94132, USA
    J Homosex 58:1355-71. 2011
    ..Few had received any formal education on LGBT issues in medical school or residency. It appears that medical schools and health care workplaces continue to ignore LGBT issues and operate in discriminatory fashion far too often...
  45. ncbi Conditions for intuitive expertise: a failure to disagree
    Daniel Kahneman
    Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, NJ 08544 0001, USA
    Am Psychol 64:515-26. 2009
    ..Subjective experience is not a reliable indicator of judgment accuracy...
  46. pmc Measuring the impact of programs that challenge the public stigma of mental illness
    Patrick W Corrigan
    Illinois Institute of Technology, 3424 S State Street, Chicago, IL 60616, USA
    Clin Psychol Rev 30:907-22. 2010
    ..Advocates have developed anti-stigma programs meant to address the prejudice and discrimination associated with these conditions...
  47. ncbi Ethnic discrimination and psychological distress: a study of Sami and non-Sami populations in Norway
    Ketil Lenert Hansen
    University of Tromsø, Norway
    Transcult Psychiatry 49:26-50. 2012
    ..Results suggest that ethnic discrimination is a major potential risk factor for poor mental health, and may contribute to ethnicity-related differences in mental health between Sami and non-Sami populations...
  48. ncbi Thinking about AIDS and stigma: a psychologist's perspective
    Gregory M Herek
    University of California, Davis, USA
    J Law Med Ethics 30:594-607. 2002
  49. ncbi Development and psychometric properties of the reported and intended behaviour scale (RIBS): a stigma-related behaviour measure
    S Evans-Lacko
    Health Service and Population Research Department, Institute of Psychiatry, King s College London, UK
    Epidemiol Psychiatr Sci 20:263-71. 2011
  50. ncbi Factors influencing social distance toward people with mental illness
    Christoph Lauber
    Psychiatric University Hospital, Zurich, Switzerland
    Community Ment Health J 40:265-74. 2004
    ..Social distance-the willingness to engage in relationships of varying intimacy with a person--is an indicator of public attitudes toward persons with mental illness...
  51. ncbi Prejudice against obesity among 10-year-olds: a nationwide population-based study
    Lena M Hansson
    Child and Adolescent Public Health Epidemiology Group, Department of Public Health Sciences, Karolinska Institutet, Sockholm, Sweden
    Acta Paediatr 98:1176-82. 2009
    Population-based research on children's possible prejudice against thin, obese and average body sizes is scarce. This study examined children's prejudice against various body sizes of both sexes...
  52. ncbi Community perceptions of tuberculosis: A qualitative exploration from a gender perspective
    F Karim
    Division of Global Health, Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden
    Public Health 125:84-9. 2011
    ..To explore community laypersons' perspective on tuberculosis (TB)-related illness experiences, meanings, behaviours and impact with reference to gender...
  53. ncbi A dynamic model of guilt: implications for motivation and self-regulation in the context of prejudice
    David M Amodio
    Department of Psychology, New York University, NY 10003, USA
    Psychol Sci 18:524-30. 2007
    ..We tested this hypothesis in the context of racial prejudice. White subjects viewed a multiracial series of faces while cortical activity was recorded using ..
  54. ncbi Effects of perceived discrimination on mental health and mental health services utilization among gay, lesbian, bisexual and transgender persons
    Diana Burgess
    Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
    J LGBT Health Res 3:1-14. 2007
    ..We examined the extent to which a recent experience of a major discriminatory event may contribute to poor mental health among LGBT persons...
  55. ncbi Facing prejudice: implicit prejudice and the perception of facial threat
    Kurt Hugenberg
    Northwestern University, USA
    Psychol Sci 14:640-3. 2003
    We propose that social attitudes, and in particular implicit prejudice, bias people's perceptions of the facial emotion displayed by others...
  56. ncbi Racism as a determinant of social and emotional wellbeing for Aboriginal Australian youth
    Naomi C Priest
    McCaughey Centre and Onemda Koori Health Unit, University of Melbourne, Melbourne, VIC npriestATunimelb edu au
    Med J Aust 194:546-50. 2011
    ..To explore the associations between self-reported racism and health and wellbeing outcomes for young Aboriginal Australian people...
  57. ncbi Development and responsiveness of a scale to measure clinicians' attitudes to people with mental illness (medical student version)
    A Kassam
    Health Service and Population Research Department, Institute of Psychiatry, King s College London, UK
    Acta Psychiatr Scand 122:153-61. 2010
  58. ncbi Experiences of discrimination: validity and reliability of a self-report measure for population health research on racism and health
    Nancy Krieger
    Harvard School of Public Health, Department of Society, Human Development, and Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Soc Sci Med 61:1576-96. 2005
  59. ncbi Objectivity in the eye of the beholder: divergent perceptions of bias in self versus others
    Emily Pronin
    Department of Psychology, Princeton University, Princeton, NJ 08544, USA
    Psychol Rev 111:781-99. 2004
    ..The authors review evidence, new and old, of this asymmetry and its underlying causes and discuss its relation to other psychological phenomena and to interpersonal and intergroup conflict...
  60. ncbi Knowing is half the battle: teaching stereotype threat as a means of improving women's math performance
    Michael Johns
    Department of Psychology, University of Arizona, Tucson, AZ 85721, USA
    Psychol Sci 16:175-9. 2005
    ..The results suggest that teaching about stereotype threat might offer a practical means of reducing its detrimental effects...
  61. pmc Measuring HIV stigma for PLHAs and nurses over time in five African countries
    William L Holzemer
    International Programs at the University of California, San Francisco, School of Nursing, USA
    SAHARA J 6:76-82. 2009
    ..These results have implications for stigma reduction interventions, particularly focused at health care providers who experience HIV stigma by association...
  62. ncbi Ambiguity in social categorization: The role of prejudice and facial affect in race categorization
    Kurt Hugenberg
    Northwestern University, USA
    Psychol Sci 15:342-5. 2004
    Two studies tested the hypothesis that perceivers' prejudice and targets' facial expressions bias race categorization in stereotypic directions...
  63. ncbi Perceptions of discrimination among persons with serious mental illness
    Patrick Corrigan
    University of Chicago Center for Psychiatric Rehabilitation, Tinley Park, Illinois, 60477, USA
    Psychiatr Serv 54:1105-10. 2003
  64. ncbi HIV-related stigma, service utilization, and status disclosure among truck drivers crossing the Southern borders in Brazil
    J Pulerwitz
    Horizons PATH, Washington, DC, USA
    AIDS Care 20:764-70. 2008
    ..As access to HIV testing and treatment improves, providers increasingly need to understand and address how stigma acts as a barrier to services...
  65. pmc Relationships of stigma and shame to gonorrhea and HIV screening
    J Dennis Fortenberry
    Section of Adolescent Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Public Health 92:378-81. 2002
    ..The purpose of this study was to assess the relationships between stigma and shame associated with seeking treatment for sexually transmitted diseases (STDs) and undergoing testing for gonorrhea and HIV...
  66. ncbi A study of discrimination within the medical community as viewed by obese patients
    Josephine Kaminsky
    North Shore Surgical Associates, Great Neck, NY, USA
    Obes Surg 12:14-8. 2002
    Although prejudice may not be verbal in nature, the lack of response from professional and non-professional medical personnel regarding the obese patients' needs (medical equipment, comfortable surroundings, properly fitting attire, etc...
  67. ncbi The impact of an intervention to change health workers' HIV/AIDS attitudes and knowledge in Nigeria: a controlled trial
    E N U Ezedinachi
    Department of Medicine, University of Calabar, Calabar, Nigeria
    Public Health 116:106-12. 2002
  68. pmc One year after ART initiation: psychosocial factors associated with stigma among HIV-positive Mozambicans
    C R Pearson
    School of Social Work, Indigenous Wellness Research Institute, University of Washington, Seattle, WA, 98105 1525, USA
    AIDS Behav 13:1189-96. 2009
    ..Most importantly, assessment and treatment of depression should be incorporated into ongoing HIV care...
  69. ncbi Subjective experiences of stigma. A focus group study of schizophrenic patients, their relatives and mental health professionals
    Beate Schulze
    University of Leipzig, Department of Psychiatry, Johannisallee 20, 04317 Leipzig, Germany
    Soc Sci Med 56:299-312. 2003
    ..The consequences for conceptualisations of stigma and the development of effective strategies to reduce stigma and discrimination because of schizophrenia are discussed...
  70. pmc Future directions in residential segregation and health research: a multilevel approach
    Dolores Acevedo-Garcia
    Department of Health and Social Behavior, Harvard School of Public Health, Boston, Mass 02115, USA
    Am J Public Health 93:215-21. 2003
  71. ncbi Hate crimes and stigma-related experiences among sexual minority adults in the United States: prevalence estimates from a national probability sample
    Gregory M Herek
    Psychology Department, University of California, Davis, California 95616, USA
    J Interpers Violence 24:54-74. 2009
    ..Employment and housing discrimination were significantly more likely among gay men and lesbians than among bisexual men and women. Implications for future research and policy are discussed...
  72. pmc Experiences of mental illness stigma, prejudice and discrimination: a review of measures
    Elaine Brohan
    Health Service and Population Research Department, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    BMC Health Serv Res 10:80. 2010
    ..This study aims to review current practice in the survey measurement of mental illness stigma, prejudice and discrimination experienced by people who have personal experience of mental illness...
  73. pmc The public's view of the competence, dangerousness, and need for legal coercion of persons with mental health problems
    B A Pescosolido
    Department of Sociology, Indiana University, Bloomington 47405, USA
    Am J Public Health 89:1339-45. 1999
    ..The authors examined Americans' opinions about financial and treatment competence of people with mental health problems, potential for harm to self or others, and the use of legal means to force treatment...
  74. ncbi Fear and social isolation as consequences of tuberculosis in VietNam: a gender analysis
    N H Long
    Health Policy Unit, Ministry of Health, Hanoi, Viet Nam
    Health Policy 58:69-81. 2001
    ..The study was conducted in four districts in different regions of Vietnam...
  75. ncbi Institutional racism in Australian healthcare: a plea for decency
    Barbara R Henry
    Social and Public Health Economics Research Group, Curtin University, Perth, WA, Australia
    Med J Aust 180:517-20. 2004
  76. pmc Perceptions of race/ethnicity-based discrimination: a review of measures and evaluation of their usefulness for the health care setting
    Nancy R Kressin
    Center for Health Quality, Outcomes and Economic Research a VA Health Services Research and Development National Center for Excellence, Bedford VA Medical Center, Bedford, MA, USA
    J Health Care Poor Underserved 19:697-730. 2008
    ..To assess discrimination in health care, reliable, valid, and comprehensive measures of racism/discrimination are needed...
  77. pmc Discriminatory attitudes and practices by health workers toward patients with HIV/AIDS in Nigeria
    Chen Reis
    Physicians for Human Rights, Boston, Massachusetts, USA
    PLoS Med 2:e246. 2005
    ..The study involved a cross-sectional survey of 1,021 Nigerian health-care professionals (including 324 physicians, 541 nurses, and 133 midwives identified by profession) in 111 health-care facilities in four Nigerian states...
  78. ncbi It's enough to make you sick: the impact of racism on the health of Aboriginal Australians
    Ann Larson
    Combined Universities Centre for Rural Health, University of Western Australia
    Aust N Z J Public Health 31:322-9. 2007
    ..Experience of interpersonal racism has been neglected as a mechanism by which inequalities between Aboriginal and non-Aboriginal people are created and maintained...
  79. ncbi Global pattern of experienced and anticipated discrimination against people with schizophrenia: a cross-sectional survey
    Graham Thornicroft
    Health Service and Population Research Department, Institute of Psychiatry, King s College London, UK
    Lancet 373:408-15. 2009
    ..We aimed to describe the nature, direction, and severity of anticipated and experienced discrimination reported by people with schizophrenia...
  80. pmc Why do providers contribute to disparities and what can be done about it?
    Diana J Burgess
    Center for Chronic Disease Outcomes Research, VA Health Services Research Center of Excellence, Minneapolis Veterans Affairs Medical Center, MN 55417, USA
    J Gen Intern Med 19:1154-9. 2004
    ..These conditions-time pressure, fatigue, and information overload-are frequently found in health care settings. We conclude with implications of the social-cognitive perspective for developing interventions to reduce provider bias...
  81. ncbi Measuring mental illness stigma
    Bruce G Link
    Department of Epidemiology, Columbia University, 722 West 168th Street, Room 1609, New York, NY 10032, USA
    Schizophr Bull 30:511-41. 2004
    ..We end by identifying gaps in stigma measurement in terms of concepts covered and populations assessed...
  82. ncbi Perceptions of tuberculosis patients about their physical, mental and social well-being: a field report from south India
    R Rajeswari
    Tuberculosis Research Centre, Indian Council of Medical Research, Mayor V R Ramanathan Road, Chetput, Chennai, India
    Soc Sci Med 60:1845-53. 2005
    ..As well, providing social support for the needy, timely counseling and health education of patients, which will alleviate mental and social sufferings of patients, should be considered...
  83. ncbi Self-reported racial discrimination and substance use in the Coronary Artery Risk Development in Adults Study
    Luisa N Borrell
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Am J Epidemiol 166:1068-79. 2007
    ..These associations were similarly positive in Whites but not significant. Substance use may be an unhealthy coping response to perceived unfair treatment for some individuals, regardless of their race/ethnicity...
  84. pmc Physician respect for patients with obesity
    Mary Margaret Huizinga
    Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, 2024 East Monument Street, Baltimore, MD 21205, USA
    J Gen Intern Med 24:1236-9. 2009
    ..Obesity stigma is common in our society, and a general stigma towards obesity has also been documented in physicians. We hypothesized that physician respect for patients would be lower in patients with higher body mass index (BMI)...
  85. ncbi A method for the quantitative analysis of the layering of HIV-related stigma
    D D Reidpath
    School of Health and Social Care, Brunel University, Uxbgidge, UK
    AIDS Care 17:425-32. 2005
    ..The importance of understanding the layering of stigma for the development of effective interventions is also discussed...
  86. pmc Racial/ethnic discrimination and common mental disorders among workers: findings from the EMPIRIC Study of Ethnic Minority Groups in the United Kingdom
    Kamaldeep Bhui
    Centre for Psychiatry, Barts, and London School of Medicine, Queen Mary, London E1 4NS, United Kingdom
    Am J Public Health 95:496-501. 2005
    ..We measured perceived discrimination and its association with common mental disorders among workers in the United Kingdom...
  87. ncbi The wage effects of obesity: a longitudinal study
    Charles L Baum
    Economics and Finance Department, Middle Tennessee State University, USA
    Health Econ 13:885-99. 2004
    ..The study closes with a discussion of the public policy implications suggested by these findings...
  88. ncbi Prejudice and schizophrenia: a review of the 'mental illness is an illness like any other' approach
    J Read
    Department of Psychology, The University of Auckland, Auckland, New Zealand
    Acta Psychiatr Scand 114:303-18. 2006
    ..Many anti-stigma programmes use the 'mental illness is an illness like any other' approach. This review evaluates the effectiveness of this approach in relation to schizophrenia...
  89. ncbi Racism and health: the relationship between experience of racial discrimination and health in New Zealand
    Ricci Harris
    Ministry of Health, Wellington, New Zealand
    Soc Sci Med 63:1428-41. 2006
    ..These results highlight the need for racism to be considered in efforts to eliminate ethnic inequalities in health...
  90. ncbi Mental health consumers' experience of stigma
    O F Wahl
    Department of Psychology, George Mason University, Fairfax, VA 22030, USA
    Schizophr Bull 25:467-78. 1999
    ..Limitations to generalization of results include the self-selection, relatively high functioning of participants, and respondent connections to a specific advocacy organization-the National Alliance for the Mentally Ill...
  91. ncbi Coping with perceived discrimination: does ethnic identity protect mental health?
    Krysia N Mossakowski
    Department of Sociology, Indiana University, 778 Ballantine Hall, 1020 East Kirkwood Ave, Bloomington, IN 47405, USA
    J Health Soc Behav 44:318-31. 2003
    ..The strong link between ethnic identity and better mental health has implications for social-psychological theories on race/ethnicity and assimilation in the United States...
  92. ncbi Perceptions of obesity across the lifespan
    Michelle R Hebl
    Department of Psychology, Rice University, Houston, Texas, USA
    Obesity (Silver Spring) 16:S46-52. 2008
    ..The current research begins to address this gap by examining the extent to which individuals between 18 and 77 years of age stereotype obesity in 20, 40, and 60-year-old targets...
  93. ncbi Weight-based stigmatization, psychological distress, & binge eating behavior among obese treatment-seeking adults
    Jamile A Ashmore
    The Cooper Aerobics Center, Dallas, TX 75230, United States
    Eat Behav 9:203-9. 2008
    ..To evaluate the associations between weight-based stigmatization, psychological distress, and binge eating behavior in a treatment-seeking obese sample...
  94. pmc Discrimination and the stress response: psychological and physiological consequences of anticipating prejudice in interethnic interactions
    Pamela J Sawyer
    Department of Psychological and Brain Sciences, University of California, Santa Barbara, CA, USA
    Am J Public Health 102:1020-6. 2012
  95. ncbi Implicit and explicit stigma of mental illness: links to clinical care
    Tara S Peris
    Division of Child and Adolescent Psychiatry, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, California 90024, USA
    J Nerv Ment Dis 196:752-60. 2008
    ..Further, explicit (but not implicit) biases predicted more negative patient prognoses, but implicit (and not explicit) biases predicted over-diagnosis, underscoring the value of using both implicit and explicit measures...
  96. ncbi Weight bias in the media: a review of recent research
    Rheanna N Ata
    Department of Psychology, University of South Florida, Tampa, FL 33620, USA
    Obes Facts 3:41-6. 2010
    ..There is ample evidence that overweight and obese individuals are stigmatized in various forms of media. This weight bias is particularly disconcerting when it targets children and adolescents...
  97. pmc Racism and health among urban Aboriginal young people
    Naomi Priest
    McCaughey Centre and Onemda VicHealth Koori Health Unit, Melbourne School of Population Health, University of Melbourne, Melbourne, Australia
    BMC Public Health 11:568. 2011
    ..Racism has been identified as an important determinant of health but few studies have explored associations between racism and health outcomes for Australian Aboriginal young people in urban areas...
  98. pmc Suicide and suicide risk in lesbian, gay, bisexual, and transgender populations: review and recommendations
    Ann P Haas
    American Foundation for Suicide Prevention, New York, New York 10005, USA
    J Homosex 58:10-51. 2011
    ..This article summarizes existing research findings, and makes recommendations for addressing knowledge gaps and applying current knowledge to relevant areas of suicide prevention practice...
  99. ncbi Does the name-race implicit association test measure racial prejudice?
    Don van Ravenzwaaij
    University of Amsterdam, The Netherlands
    Exp Psychol 58:271-7. 2011
    ..One interpretation of this result is that the IAT measures latent racial prejudice. An alternative explanation is that the result is due to differences in in-group/out-group membership...
  100. pmc HIV-related discriminatory attitudes of healthcare workers in Bangladesh
    Mohammad Bellal Hossain
    Public and Environmental Health Research Unit, Department of Public Health and Policy London School of Hygiene and Tropical Medicine, 51 Bedford Square, London, WCI B 3DP, UK
    J Health Popul Nutr 28:199-207. 2010
    ..The results indicate that programmes to reduce irrational fear about transmission of HIV are urgently needed...
  101. pmc Disentangling the stigma of HIV/AIDS from the stigmas of drugs use, commercial sex and commercial blood donation - a factorial survey of medical students in China
    Kit Yee Chan
    School of Health and Social Development, Deakin University, Burwood Highway, Burwood, Victoria 3125, Australia
    BMC Public Health 7:280. 2007
    ..This paper describes an experimental study for disentangling the layering of HIV/AIDS related stigmas...

Research Grants75

  1. Genetic variation and regulatory networks: Mechanisms and complexity
    DANA PE ER; Fiscal Year: 2009
    ..These tools will be made publicly available, including a friendly graphical user interface and visualization. ..
  2. Mapping for Specialized Domains for FCeRI Signaling &Internalization
    Bridget S Wilson; Fiscal Year: 2013
    ..Results of these analyses will contribute important new insight into the nature and assembly of membrane microdomains controlling immune cell signaling. ..
  3. Genome-wide recombination as a risk factor for nondisjunction
    NATASHA D HOLLIS; Fiscal Year: 2010
    ..The reference letters are strong. She has the necessary package to excel as a pre-doctoral fellow. ..
    Joann A Boughman; Fiscal Year: 2011
    ..apos;^g,} To add more Project Nan^ative File attachments, please use the attachment buttons below. Add QptionalvRrbject Narrative File Delete Optional Project Narrative,File View Qptional:Prdject Narrative-File ..
  5. Functional Analysis of the Dual Specificity Kinase NEK1 in Mammalian Meiosis
    JOANNA KIM HOLLOWAY; Fiscal Year: 2011
    ..Understanding the role of key genes involved in ensuring proper chromosomal segregation during meiosis will increase our understanding of the mechanisms controlling these events and the complex causes of infertility. ..
  6. Integrating stress MAP kinase signaling with DNA replication origin licensing
    Jeanette Gowen Cook; Fiscal Year: 2013
    Lawrence C Layman; Fiscal Year: 2013
    ..We hope to understand how mutations in two genes (CHD7 and NELF) disrupt puberty and cause infertility in humans. These human studies will be complemented by experiments in relevant cell types and an animal model. ..
  8. Functional study of C53 protein as a novel regulator of checkpoint kinases
    Honglin Li; Fiscal Year: 2012
    ..It will lay a foundation for further exploitation of this novel protein as a potential therapeutic target in fighting diseases such as cancer. ..
  9. Cooperative Multicenter Reproductive Medicine Network (U10)
    MARCELLE IVONNE CEDARS; Fiscal Year: 2013
    ..In this proposal, drawing from studies of somatic aging, we propose a novel treatment to improve mitochondrial function and potentially reverse the age- associated decline in fertility...
  10. A Cis-regulatory Model for Neural Border Induction
    Daniel Meulemans Medeiros; Fiscal Year: 2013
    ..The proposed work will support the training of one postdoctoral scholar for two years. ..
  11. Chromosomal Control of Segregation of C. Elegans
    Abby F Dernburg; Fiscal Year: 2013
    ..Through these approaches, we will learn how this molecular machine assembles from its component parts to govern the reassortment of genetic traits during sexual reproduction. ..
  12. Roles of the mammalian CST complex in DNA replication and chromosome cohesion
    JASON AARON STEWART; Fiscal Year: 2013
    ..The completion of these studies will advance our understanding of these cellular processes and provide new targets for prevention and treatment of these diseases. ..
    Katherine L Wilson; Fiscal Year: 2012
    ..Aim 3 is a whole-genome and promoter-specific analysis of BAF function in C. elegans, which is expected to identify genes relevant to its roles in muscle and DNA- damage responses. ..
  14. The role of satellite rasiRNA in the Segregation Distorter system of Drosophila
    ..If SD affects Rsp rasiRNA production, then SD genotype will correlate with Rsp rasiRNA abundance in postmeiotic testis dissections. ..
    Barbara J Meyer; Fiscal Year: 2013
    ..Our protein complexes give us insight into the mechanisms underlying the genome rearrangements associated with such a cancerous state. ..
  16. Molecular Analysis of Pericentric Sister Chromatid Cohesion
    PAUL CONNOR MEGEE; Fiscal Year: 2013
  17. Assembly and Maintenance of Centromeres in Filamentous Fungi
    Michael Freitag; Fiscal Year: 2013
  18. Centromere Structure and Function in Candida albicans
    Judith G Berman; Fiscal Year: 2012
    ..We will develop tools to study this process and will identify companion drugs that inhibit these defects, thereby extending the usefulness of available antifungal therapies. ..
  19. Mechanisms of arsenic-induced chromosomal instability and carcinogenesis
    Wei Dai; Fiscal Year: 2013
    ..We anticipate that this line of research will lead to the identification of key molecular targets for cancer intervention, as well as for ameliorating the detrimental effects of arsenic compounds. ..
  20. FASEB SRC on Yeast Chromosome Structure, Replication and Segregation
    Scott Keeney; Fiscal Year: 2012
    ..This conference brings together the principal investigators studying chromosome biology in yeasts. ..
  21. Checkpoints and double strand breaks in S. pombe meiosis
    Susan L Forsburg; Fiscal Year: 2013
    ..This will provide important insights into the stresses that impact meiotic progression in humans as well as yeast. ..
  22. Meiosis, SUMOylation and the ZIP3 Protein: Parallel Studies in Mouse and Yeast.
    Neil Hunter; Fiscal Year: 2012
    ..Defects in these processes are linked to human infertility, miscarriage and genetic diseases, particularly cancer. A greater understanding of their mechanism and regulation will help us better understand the etiology of these diseases. ..
  23. E2-Cellular Complexes in HPV Chromatin Transcription
    Cheng Ming Chiang; Fiscal Year: 2013
  24. Phylogenomics and functional diversification of the Heterochromatin Protein 1 gen
    MIA TAUNA LEVINE; Fiscal Year: 2012
    ..My evolutionary/comparative genomic approach promises to identify new biological functions for HP1 genes that advance our understanding of the gene regulation and chromosome segregation defects in cancer cells. ..
  25. Environmental Endocrine Disruptors and Human Sperm Chromosomal Abnormalities
    Melissa Perry; Fiscal Year: 2012
    ..This study investigates whether chemicals common in our daily environment can affect male fertility and potential risks for birth defects. ..
  26. Colonic Cytokinetics and Cell Signaling: Dietary Effects
    ROBERT STEPHEN CHAPKIN; Fiscal Year: 2012
  27. Non-coding RNAs in the epigenetics of human centromere formation
    PETER WARBURTON; Fiscal Year: 2009
    ..These epigenetic marks are currently unknown in human cells, and their discovery will provide great insight into the requirements for centromere formation and function. ..
  28. The CAK Network in Metazoan Cell Cycle Regulation
    Robert P Fisher; Fiscal Year: 2010
  29. Establishment of sister chromatid cohesion
    Douglas E Koshland; Fiscal Year: 2013
    ..Mutations in human genes encoding Smc proteins have been linked to cancer, birth defects and disorders. ..
    Susan K Dutcher; Fiscal Year: 2013
    ..The maturation of centrioles/basal bodies during the cell cycle is likely to play important roles in both asymmetric cell division and signaling. ..
  31. LANA and Cellular Gene Expression
    ROLF F RENNE; Fiscal Year: 2013
    ..More specifically, we study how LANA supports the replication of the viral genome and how it helps to recruit the above mentioned factors. ..
  32. Regulation of chromosome segregation by SMC complexes and Top2 in S. pombe
    MATTHEW J O'CONNELL; Fiscal Year: 2013
    ..This project studies proteins that are essential for accurate inheritance of chromosomes as cells divide. The public health relevance is thus central to the biology of cancer and aging. ..
  33. The Molecular Basis of Allorecognition in Social Amoeba
    Gad Shaulsky; Fiscal Year: 2013
    ..We found that the tgrB1 and tgrC1 are enriched in prestalk cells so we propose to use conditional expression and chimeric aggregates to test the possible role of these genes in cell-type differentiation and tissue segregation. ..
  34. Design of a high-throughput screen for chemicals that cause meiotic aneuploidy
    Patrick Allard; Fiscal Year: 2011
  35. Morphogenesis of mammalian gut endoderm
    Anna Katerina Hadjantonakis; Fiscal Year: 2012
    ..We will test the hypothesis that extraembryonic (visceral) endoderm is not an exclusively extraembryonic tissue using a genetic induced fate mapping approach. ..
  36. Mitochondrial Gene Therapy
    Shoukhrat M Mitalipov; Fiscal Year: 2013
    ..In this study, we will explore feasibility, efficiency and safety of this novel mitochondrial gene replacement therapy in a clinically relevant nonhuman primate model. ..
  37. The Synapsis Checkpoint in C. elegans Meiosis
    Needhi Bhalla; Fiscal Year: 2013
    Barry P Sleckman; Fiscal Year: 2012
    ..We now propose to identify histone modifications that function as intermediates to coordinate the normal repair of DNA-DSBs in mammalian cells. ..
  39. Genetics of Meiosis and Recombination in Mice
    John C Schimenti; Fiscal Year: 2013
    ..In sum, this project will elucidate the genetic quality control mechanisms operate in mammalian gametes. Arguably, this is one of the most important processes for the health and success of our species and others. ..
  40. Epigenetic control of sex chromosome behavior in meiosis.
    JoAnne Engebrecht; Fiscal Year: 2013
    ..Importantly, these studies will also elucidate general mechanisms of DNA repair and checkpoint signaling, which play critical roles in monitoring and maintaining genome integrity in all cells. ..
  41. Mechanisms of Viral DNA Packaging
    CARLOS JOSE BUSTAMANTE; Fiscal Year: 2013
    ..Finally, we wish to investigate how the increasing internal DNA pressure regulates the dynamics of the motor during packaging. ..
  42. Kinetics of Chromosome Synapsis During Meiosis
    Jennifer C Fung; Fiscal Year: 2013
    ..Such research may lead to new ideas for treatment of infertility or to development of diagnostic tests to detect potential problems of chromosome segregation early on before expensive medical and surgical treatments are attempted. ..
    Neil Osheroff; Fiscal Year: 2013
    ..Bacillus anthracis gyrase and topoisomerase IV will be used for some experiments to provide comparisons between the prokaryotic and eukaryotic type II enzymes. ..
  44. Genetic conflict shapes centromeres and heterochromatin
    Harmit S Malik; Fiscal Year: 2013
    ..This proposal aims to employ this novel approach to understand the biological forces shaping these evolutionarily and medically important components of eukaryotic genomes, using the Drosophila model genetic system. ..
  45. Developmental Regulation of the Cell Cycle in Drosophila
    LAURA ANNE LEE; Fiscal Year: 2013
    ..Because the vertebrate homolog of ASUN also controls dynein localization in cultured human cells during mitosis, elucidation of the mechanism of action of ASUN may have important implications for human diseases such as cancer. ..
  46. Genetic analysis of DNA methylation in Neurospora crassa
    ANDREW DAVID KLOCKO; Fiscal Year: 2013
    ..In addition, identifying putative genes that could become mutated for the progression of cancer is essential to develop treatments or prevention strategies for cancer patients. ..
  47. Role of ORCA in DNA replication
    Supriya Gangadharan Prasanth; Fiscal Year: 2013
    ..This proposal is therefore highly significant not only in understanding the basics of how replication and cell cycle progression is coordinated but also significant for the field of cancer biology. ..
  48. Characterization of a bacteriophage tubulin involved in viral replication
    JOSEPH A POGLIANO; Fiscal Year: 2013
    ..5. Perform electron tomography and cryoTomography at various stages of infection to gain high resolution insights into the structural organization of PhuZ and viral capsids assembled in vivo during lytic growth. ..
  49. Role of microRNA in HIV associated neurological disorder (HAND).
    Bassel E Sawaya; Fiscal Year: 2013
    ..Outcome from these studies will serve to prevent and/or delay neuronal deregulation and disorders observed in AIDS patients. ..
    Anthony P Bretscher; Fiscal Year: 2013
  51. Cancer prevention, mental health and social capital of segregated Black Americans
    LORRAINE TIERA DEAN; Fiscal Year: 2010
    ..Data will be aggregated and geocoded to segregated areas of Philadelphia County using a novel measure of segregation based on 2000 US Census Data. ..
  52. Psychosocial Factors and the Risk of Incident Asthma in African American Women
    Patricia F Coogan; Fiscal Year: 2013
    ..abstract_text> ..
  53. Control of Oocyte Maturation in C. elegans
    DAVID IRWIN GREENSTEIN; Fiscal Year: 2013
    ..The small roundworm C. elegans is an established model for studying the hormonal control of meiosis. These studies will define the signaling mechanisms controlling female meiosis and provide insights into the origin of meiotic errors. ..
  54. Sexual conflict and relocation of genes by duplication
    ESTHER BETRAN; Fiscal Year: 2013
    ..Whole genome polymorphism data from D. melanogaster and comparative genomics will be exploited using the most current bioinformatics tools and molecular evolution software to achieve these objectives. ..
  55. Identification of DNA Elements Governing Chromatin Function in C elegans
    Jason D Lieb; Fiscal Year: 2011
    ..elegans research will provide an important milestone in meeting the challenge of using genome sequence information to understand and predict biological functions. ..
  56. Genetics of the formation of repair &recombination foci
    RODNEY J ROTHSTEIN; Fiscal Year: 2013
    ..Model systems have provided a glimpse into the mechanisms responsible for the repair of DNA damage. In this proposal, we will explore the genetic and cell biological control of DNA repair processes. ..
  57. Organization and Regulation of Eukaryotic Centromeres
    BETH SULLIVAN; Fiscal Year: 2009
    ..We propose to investigate the roles of genomic structure and chromatin organization and dynamics in assembly and regulation of CENP-A chromatin, centromeric domains, and metaphase kinetochore structure. ..
  58. Pathogenetics of the FOX transcription factor gene cluster on 16q24.1
    Pawel Stankiewicz; Fiscal Year: 2013
    ..Moreover, the risks related to this experimental therapy may be justified from a risk: benefit standpoint and have potential to be translated in the hospital setting. ..
  59. Kinetochore Function and Cell Cycle Progression Revision
    Katsumi Kitagawa; Fiscal Year: 2012
    ..Having an abnormal number of chromosomes is called aneuploidy, and this situation can cause cancer to develop. Our studies on the mechanism of chromosome segregation will therefore contribute to the understanding of cancer development. ..
  60. College of Medicine Phoenix Campus Vivarium Phase I Construction
    William M Crist; Fiscal Year: 2010
    ..The best and only way to assure optimal standards of experimental animal care required for our PHS-supported research efforts is to construct this dedicated laboratory animal vivarium serving the Phoenix Biomedical Campus. ..
  61. Homolog orientation and segregation in acentrosomal meiosis
    Kim S McKim; Fiscal Year: 2013
    ..Finally, we will test the hypothesis that the bi-orientation of homologs depends on an interaction between chromosome associated and central spindle microtubules. ..
  62. Integrating cell sorting and tissue shaping mechanisms during cornea maturation
    Philip M Iannaccone; Fiscal Year: 2010
    KENT GOLIC; Fiscal Year: 2002
    Clarence Chan; Fiscal Year: 1999
    ..An alternative explanation would be that the sli mutations lead to an overproduction of PP1. He suggests experiments to test all three hypotheses, as well as the cloning and characterization of the wild type sli genes. ..
    Greg Hunt; Fiscal Year: 2000
    ..3 cM with 95% confidence. It is proposed to use STS primers designed from the RAPD markers, SSCP polymorphisms and further development of another set of RAPD markers from 1000 10-mer primers, screened in bulk. ..
  66. Comparative and functional proteomics of germline chromatin in C. elegans
    KENNETH HILLERS; Fiscal Year: 2009
    ..elegans to identify proteins involved in gamete production. Information gained from these studies may help with diagnosis and/or treatment of human reproductive problems. ..
    Dean Dawson; Fiscal Year: 1992
    ..The goal here is to acquire a set of mutant strains and cloned genes which can be used as tools to examine how this system functions in yeast and whether it is common to other organisms...
  68. Structural mechanism of DNA segregation by the pSK41 par system
    Maria Schumacher; Fiscal Year: 2010
    ..Thus, understanding the structural basis for DNA segregation by this par system will provide several points of potential therapeutic intervention against pSK41 harboring multidrug resistant S. aureus strains. ..
    Eric Vanman; Fiscal Year: 2000 psychology has focused largely on beliefs, stereotypes, and other cognitive aspects that might underlie prejudice. More recent and empirical work, however, has argued that a consideration of prejudice solely as a "phenomenon ..
  70. Automated analysis of cell cycle genes in Trypanosoma brucei
    LAWRENCE RUBEN; Fiscal Year: 2009
    ..The fluorescently tagged cell lines will also be useful for other public health studies where a rapid evaluation of organelle replication and segregation is important. ..
  71. Insulin and Oocyte Chromatin Segregation
    Gary Smith; Fiscal Year: 2009
    ..abstract_text> ..
  72. The Emergence and Development of Social Group Attitudes
    KRISTINA OLSON; Fiscal Year: 2010
    ..There is now considerable evidence that experienced and perceived prejudice and discrimination contribute to mental and physical health problems (for a review see Mays et al., 2007)...
  73. A multilevel approach to understanding healthcare disparities in the nursing home
    LATARSHA CHISHOLM; Fiscal Year: 2009
    ..The goal of this study is to move from documenting racial/ethnic disparities to understanding pathways that may lead to racial/ethnic disparities. ..
  74. Molecular Structure of Yeast Chromosome 1
    DAVID KABACK; Fiscal Year: 2005
    ..abstract_text> ..
    Sander van den Heuvel; Fiscal Year: 2003
    ..Our goals are 1) to determine the function of the lin-5 gene, 2) to identify novel components of the mitotic machinery and 3) to understand how they work together with known components to regulate chromosome segregation. ..