rotator cuff

Summary

Summary: The musculotendinous sheath formed by the supraspinatus, infraspinatus, subscapularis, and teres minor muscles. These help stabilize the head of the HUMERUS in the glenoid fossa and allow for rotation of the SHOULDER JOINT about its longitudinal axis.

Top Publications

  1. ncbi Platelet-rich plasma augmentation for arthroscopic rotator cuff repair: a randomized controlled trial
    Roberto Castricini
    Department of Orthopaedic and Trauma Surgery, Ospedale Civile, Jesi, Italy
    Am J Sports Med 39:258-65. 2011
  2. ncbi The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears
    Leesa M Galatz
    Shoulder and Elbow Service, Department of Orthopaedic Surgery, Washington University School of Medicine at Barnes Jewish Hospital, One Barnes Jewish Hospital Plaza, Suite 11300, West Pavilion, St Louis, MO 63110, USA
    J Bone Joint Surg Am 86:219-24. 2004
  3. ncbi Long-term outcome after structural failure of rotator cuff repairs
    Bernhard Jost
    Department of Orthopedics, University of Zurich, Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    J Bone Joint Surg Am 88:472-9. 2006
  4. ncbi The results of repair of massive tears of the rotator cuff
    C Gerber
    Department of Orthopaedics, University of Zurich, Switzerland
    J Bone Joint Surg Am 82:505-15. 2000
  5. ncbi Physical examination tests of the shoulder: a systematic review with meta-analysis of individual tests
    E J Hegedus
    Duke University, DUMC 3907, Durham, NC 27710, USA
    Br J Sports Med 42:80-92; discussion 92. 2008
  6. ncbi The outcome and structural integrity of arthroscopic rotator cuff repair with use of the double-row suture anchor technique
    Laurent Lafosse
    The Alps Surgery Institute, Clinique Generale, 4 Ch Tour Reine, 74000 Annecy, France
    J Bone Joint Surg Am 89:1533-41. 2007
  7. ncbi Rotator cuff repair. A biomechanical comparison of three techniques
    Robert L Waltrip
    American Sports Medicine Institute, Birmingham, Alabama, USA
    Am J Sports Med 31:493-7. 2003
  8. pmc Development of fatty atrophy after neurologic and rotator cuff injuries in an animal model of rotator cuff pathology
    Kasra Rowshan
    2226 Gillespie Neuroscience Research Facility, University of California at Irvine, Irvine, CA 92697 4292, USA
    J Bone Joint Surg Am 92:2270-8. 2010
  9. ncbi Factors affecting healing rates after arthroscopic double-row rotator cuff repair
    Robert Z Tashjian
    Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, 84108, USA
    Am J Sports Med 38:2435-42. 2010
  10. ncbi Accuracy of MRI, MR arthrography, and ultrasound in the diagnosis of rotator cuff tears: a meta-analysis
    Joseph O de Jesus
    Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107 5244, USA
    AJR Am J Roentgenol 192:1701-7. 2009

Detail Information

Publications351 found, 100 shown here

  1. ncbi Platelet-rich plasma augmentation for arthroscopic rotator cuff repair: a randomized controlled trial
    Roberto Castricini
    Department of Orthopaedic and Trauma Surgery, Ospedale Civile, Jesi, Italy
    Am J Sports Med 39:258-65. 2011
    After reinsertion on the humerus, the rotator cuff has limited ability to heal. Growth factor augmentation has been proposed to enhance healing in such procedure.
  2. ncbi The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears
    Leesa M Galatz
    Shoulder and Elbow Service, Department of Orthopaedic Surgery, Washington University School of Medicine at Barnes Jewish Hospital, One Barnes Jewish Hospital Plaza, Suite 11300, West Pavilion, St Louis, MO 63110, USA
    J Bone Joint Surg Am 86:219-24. 2004
    The impact of a recurrent defect on the outcome after rotator cuff repair has been controversial...
  3. ncbi Long-term outcome after structural failure of rotator cuff repairs
    Bernhard Jost
    Department of Orthopedics, University of Zurich, Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    J Bone Joint Surg Am 88:472-9. 2006
    In a previous study, twenty consecutive patients with a rerupture of the rotator cuff, as documented with magnetic resonance imaging, were found to have significantly less pain and better function and strength, compared with the ..
  4. ncbi The results of repair of massive tears of the rotator cuff
    C Gerber
    Department of Orthopaedics, University of Zurich, Switzerland
    J Bone Joint Surg Am 82:505-15. 2000
    Massive tears of the tendons of the rotator cuff cause atrophy and fatty degeneration of the rotator cuff muscles and painful loss of function of the shoulder...
  5. ncbi Physical examination tests of the shoulder: a systematic review with meta-analysis of individual tests
    E J Hegedus
    Duke University, DUMC 3907, Durham, NC 27710, USA
    Br J Sports Med 42:80-92; discussion 92. 2008
    ..To compile and critique research on the diagnostic accuracy of individual orthopaedic physical examination tests in a manner that would allow clinicians to judge whether these tests are valuable to their practice...
  6. ncbi The outcome and structural integrity of arthroscopic rotator cuff repair with use of the double-row suture anchor technique
    Laurent Lafosse
    The Alps Surgery Institute, Clinique Generale, 4 Ch Tour Reine, 74000 Annecy, France
    J Bone Joint Surg Am 89:1533-41. 2007
    The reported rate of failure after arthroscopic rotator cuff repair has varied widely. The influence of the repair technique on the failure rates and functional outcomes after open or arthroscopic rotator cuff repair remains controversial...
  7. ncbi Rotator cuff repair. A biomechanical comparison of three techniques
    Robert L Waltrip
    American Sports Medicine Institute, Birmingham, Alabama, USA
    Am J Sports Med 31:493-7. 2003
    The most common complication of rotator cuff repair is structural failure at the repair site. A single-layer repair does not adequately reproduce the anatomic insertion and may not optimize fixation strength.
  8. pmc Development of fatty atrophy after neurologic and rotator cuff injuries in an animal model of rotator cuff pathology
    Kasra Rowshan
    2226 Gillespie Neuroscience Research Facility, University of California at Irvine, Irvine, CA 92697 4292, USA
    J Bone Joint Surg Am 92:2270-8. 2010
    Detachment of a tendon from its osseous insertion, as can be the case with severe rotator cuff injuries, leads to atrophy of and increased fat in the corresponding muscle...
  9. ncbi Factors affecting healing rates after arthroscopic double-row rotator cuff repair
    Robert Z Tashjian
    Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, 84108, USA
    Am J Sports Med 38:2435-42. 2010
    Double-row arthroscopic rotator cuff repairs were developed to improve initial biomechanical strength of repairs to improve healing rates. Despite biomechanical improvements, failure of healing remains a clinical problem.
  10. ncbi Accuracy of MRI, MR arthrography, and ultrasound in the diagnosis of rotator cuff tears: a meta-analysis
    Joseph O de Jesus
    Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107 5244, USA
    AJR Am J Roentgenol 192:1701-7. 2009
    The purpose of this study was to compare the diagnostic accuracy of MRI, MR arthrography, and ultrasound for the diagnosis of rotator cuff tears through a meta-analysis of the studies in the literature.
  11. ncbi Efficacy and safety of corticosteroid injections and other injections for management of tendinopathy: a systematic review of randomised controlled trials
    Brooke K Coombes
    Division of Physiotherapy, School of Health and Rehabilitation Sciences, University of Queensland, St Lucia, Queensland, Australia
    Lancet 376:1751-67. 2010
    ..Few evidence-based treatment guidelines for tendinopathy exist. We undertook a systematic review of randomised trials to establish clinical efficacy and risk of adverse events for treatment by injection...
  12. ncbi Single-row versus double-row arthroscopic rotator cuff repair: a prospective randomized clinical study
    Andrea Grasso
    Villa Valeria Clinic, Rome, Italy
    Arthroscopy 25:4-12. 2009
    The purpose of this study was to compare the clinical outcome of arthroscopic rotator cuff repair with single-row and double-row techniques.
  13. ncbi Bone marrow-derived mesenchymal stem cells transduced with scleraxis improve rotator cuff healing in a rat model
    Lawrence V Gulotta
    Hospital for Special Surgery, New York, NY 10021, USA
    Am J Sports Med 39:1282-9. 2011
    ..of this study was to determine if the application of mesenchymal stem cells (MSCs) transduced with adenoviral-mediated scleraxis (Ad-Scx) could improve regeneration of the tendon-bone insertion site in a rat rotator cuff repair model.
  14. ncbi Repair integrity and functional outcome after arthroscopic double-row rotator cuff repair. A prospective outcome study
    Hiroyuki Sugaya
    Funabashi Orthopaedic Sports Medicine Center, 1 833 Hazama, Funabashi, Chiba 2740822, Japan
    J Bone Joint Surg Am 89:953-60. 2007
    The retear rate following rotator cuff repair is variable...
  15. ncbi Influence of cuff muscle fatty degeneration on anatomic and functional outcomes after simple suture of full-thickness tears
    Daniel Goutallier
    Department of Orthopedic Surgery, Henri Mondor Hospital, University of Paris, Creteil, France
    J Shoulder Elbow Surg 12:550-4. 2003
    Two hundred twenty shoulders with a rotator cuff tear repaired by simple tendon-to-bone suture were analyzed to determine whether the severity of presurgical fatty degeneration had an influence on their anatomic and functional outcome...
  16. ncbi Which method of rotator cuff repair leads to the highest rate of structural healing? A systematic review
    Thomas R Duquin
    Department of Orthopaedic Surgery, University at Buffalo, Buffalo, NY, USA
    Am J Sports Med 38:835-41. 2010
    The purpose of rotator cuff repair is to diminish pain and restore function, and this most predictably occurs when the tendon is demonstrated to heal...
  17. ncbi Diabetes mellitus impairs tendon-bone healing after rotator cuff repair
    Asheesh Bedi
    Laboratory for Soft Tissue Research, Hospital for Special Surgery, New York, NY 10021, USA
    J Shoulder Elbow Surg 19:978-88. 2010
    ..Studies have demonstrated a significant decrease in skeletal mass, bone mineral density, and impaired fracture healing in the diabetic population. However, the effect of sustained hyperglycemia on tendon-to-bone healing is unknown...
  18. ncbi Mechanical strength of arthroscopic rotator cuff repair techniques: an in vitro study
    Alberto G Schneeberger
    Department of Orthopaedic Surgery, University of Zurich, Balgrist, Zurich, Switzerland
    J Bone Joint Surg Am 84:2152-60. 2002
    Retears after rotator cuff repairs occur relatively frequently and may compromise the functional result...
  19. ncbi The role of platelet-rich plasma in arthroscopic rotator cuff repair: a systematic review with quantitative synthesis
    Jaskarndip Chahal
    Division of Sports Medicine, Rush University Medical Center, Chicago, Illinois, USA
    Arthroscopy 28:1718-27. 2012
    Despite the theoretic basis and interest in using platelet-rich plasma (PRP) to improve the potential for rotator cuff healing, there remains ongoing controversy regarding its clinical efficacy...
  20. ncbi Tears at the rotator cuff footprint: prevalence and imaging characteristics in 305 MR arthrograms of the shoulder
    Christoph Schaeffeler
    Department of Radiology, Technische Universitat Munchen, Klinikum rechts der Isar, Ismaninger Str 22, 81675 Munich, Germany
    Eur Radiol 21:1477-84. 2011
    To evaluate the prevalence, imaging characteristics and anatomical distribution of tears at the rotator cuff (RC) footprint with MR arthrography (MR-A) of the shoulder.
  21. ncbi The effects of fibroblast growth factor-2 on rotator cuff reconstruction with acellular dermal matrix grafts
    Junji Ide
    Department of Orthopaedic and Neuro Musculoskeletal Surgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    Arthroscopy 25:608-16. 2009
    Our purpose was to determine whether the local application of fibroblast growth factor (FGF) 2 accelerates regeneration and remodeling of rotator cuff tendon defects reconstructed with acellular dermal matrix (ADM) grafts in rats.
  22. ncbi Systematic review of arthroscopic rotator cuff repair and mini-open rotator cuff repair
    Shane J Nho
    The Hospital for Special Surgery, New York, NY 10021, USA
    J Bone Joint Surg Am 89:127-36. 2007
  23. ncbi Results of proximal humeral locked plating with supplemental suture fixation of rotator cuff
    Brian Badman
    UAP Bone and Joint Union Hospital, Terre Haute, IN, USA
    J Shoulder Elbow Surg 20:616-24. 2011
    ..We hypothesized that treatment of these injuries through a standardized technique of precountored locked plating and supplemental tension band suture fixation would result in improved clinical outcomes...
  24. ncbi Platelet-rich plasma stimulates cell proliferation and enhances matrix gene expression and synthesis in tenocytes from human rotator cuff tendons with degenerative tears
    Chris Hyunchul Jo
    Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul, Korea
    Am J Sports Med 40:1035-45. 2012
    Platelet-rich plasma (PRP) contains various growth factors and appears to have a potential to promote tendon healing, but evidence is lacking regarding its effect on human tenocytes from rotator cuff tendons with degenerative tears.
  25. ncbi Evaluation of a cross-linked acellular porcine dermal patch for rotator cuff repair augmentation in an ovine model
    Gregory P Nicholson
    Rush University Medical Center, Chicago, IL, USA
    J Shoulder Elbow Surg 16:S184-90. 2007
    In this study we evaluated 2 commercially available rotator cuff repair augmentation patches in an in vivo sheep model using mechanical testing and histologic techniques...
  26. ncbi Outcomes of single-row and double-row arthroscopic rotator cuff repair: a systematic review
    Paul Saridakis
    Department of Orthopaedics, The Ohio State University, 2050 Kenny Road, Columbus, OH 43221, USA
    J Bone Joint Surg Am 92:732-42. 2010
    Arthroscopic rotator cuff repair is a common procedure that is gaining wide acceptance among orthopaedic surgeons because it is less invasive than open repair techniques...
  27. ncbi Magnetic resonance imaging of arthroscopic supraspinatus tendon repair
    Dennis Liem
    Shoulder and Elbow Service, ATOS Clinic Heidelberg, Heidelberg, Germany
    J Bone Joint Surg Am 89:1770-6. 2007
    While a number of studies have documented the very good clinical results of arthroscopic rotator cuff repair, very few authors have specifically assessed cuff integrity, supraspinatus atrophy, and fatty infiltration and their influence on ..
  28. ncbi Prospective randomized clinical trial of single- versus double-row suture anchor repair in 2- to 4-cm rotator cuff tears: clinical and magnetic resonance imaging results
    Kyoung Hwan Koh
    Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
    Arthroscopy 27:453-62. 2011
    The purpose of this study was to compare the clinical outcomes and the retear rates of arthroscopic single-row (SR) and double-row (DR) suture anchor repair in 2- to 4-cm rotator cuff tears.
  29. ncbi Augmentation of a rotator cuff suture repair using rhPDGF-BB and a type I bovine collagen matrix in an ovine model
    Christopher K Hee
    Sports Medicine, BioMimetic Therapeutics, Franklin, Tennessee 37067, USA
    Am J Sports Med 39:1630-9. 2011
    b>Rotator cuff tears are a common source of shoulder pain. High rates (20%-94%) of structural failure of the repair have been attributed to multiple factors, including poor repair tissue quality and tendon-to-bone integration...
  30. ncbi Sustained delivery of transforming growth factor beta three enhances tendon-to-bone healing in a rat model
    Cionne N Manning
    Department of Orthopaedic Surgery, Washington University, 660 South Euclid, Campus Box 8233, St Louis, Missouri 63110, USA
    J Orthop Res 29:1099-105. 2011
    Despite advances in surgical technique, rotator cuff repairs are plagued by a high rate of failure...
  31. ncbi Evaluation of an exercise concept focusing on eccentric strength training of the rotator cuff for patients with subacromial impingement syndrome
    Susanne Bernhardsson
    Physiotherapy Clinic at Mölnlycke Health Care Center, Primary Care Southern Bohuslän and Institute of Neuroscience and Physiology Physiotherapy, Sahlgrenska Academy at University of Gothenburg
    Clin Rehabil 25:69-78. 2011
    To evaluate the effect on pain intensity and function of an exercise concept focusing on specific eccentric strength training of the rotator cuff in patients with subacromial impingement syndrome.
  32. ncbi Conservative treatment and rotator cuff tear progression
    Umile Giuseppe Longo
    Department of Orthopaedic and Trauma Surgery, Campus Bio Medico University, Rome, Italy
    Med Sport Sci 57:90-9. 2012
    There is no definite consensus on the best management for patients with rotator cuff tears. No randomized controlled studies have compared the outcome of surgical versus conservative treatment...
  33. ncbi Clinical outcome and imaging of arthroscopic single-row and double-row rotator cuff repair: a prospective randomized trial
    Hsiao Li Ma
    National Yang Ming University School of Medicine, Taipei, Taiwan
    Arthroscopy 28:16-24. 2012
    ..of this study was to compare the clinical and imaging outcomes of single-row and double-row suture anchor fixation in arthroscopic rotator cuff repair with emphasis on analysis of the effect of various tear size on repair integrity.
  34. ncbi Adenoviral-mediated gene transfer of human bone morphogenetic protein-13 does not improve rotator cuff healing in a rat model
    Lawrence V Gulotta
    Hospital for Special Surgery, New York, New York 10021, USA
    Am J Sports Med 39:180-7. 2011
    b>Rotator cuff tendon-to-bone healing occurs by formation of a scar tissue interface after repair, which makes it prone to failure...
  35. pmc Symptomatic progression of asymptomatic rotator cuff tears: a prospective study of clinical and sonographic variables
    Nathan A Mall
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 92:2623-33. 2010
    ..to identify changes in tear dimensions, shoulder function, and glenohumeral kinematics when an asymptomatic rotator cuff tear becomes painful and to identify characteristics of individuals who develop pain compared with those who ..
  36. ncbi Arthroscopic repair of massive rotator cuff tears with stage 3 and 4 fatty degeneration
    Stephen S Burkhart
    Department of Orthopaedic Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Arthroscopy 23:347-54. 2007
    The purpose of this study was to assess the functional results of arthroscopic repair of massive rotator cuff tears in patients who had stage 3 and 4 fatty degeneration of the rotator cuff musculature, according to the Goutallier scale.
  37. ncbi The effect of recombinant human platelet-derived growth factor BB-coated sutures on rotator cuff healing in a sheep model
    Christopher Uggen
    Kerlan Jobe Orthopaedic Clinic, Los Angeles, California, U S A
    Arthroscopy 26:1456-62. 2010
    ..was to determine whether suture could be coated with recombinant human platelet-derived growth factor BB (rhPDGF-BB) and whether the coated suture would improve histologic scores and biomechanical strength of sheep rotator cuff repairs.
  38. ncbi Histopathology of the supraspinatus tendon in rotator cuff tears
    Umile Giuseppe Longo
    Department of Orthopaedic and Trauma Surgery, Campus Biomedico University, Rome, Italy
    Am J Sports Med 36:533-8. 2008
    Causes of rotator cuff pathology are poorly understood.
  39. ncbi Gene expression analysis in calcific tendinopathy of the rotator cuff
    F Oliva
    Department of Trauma and Orthopaedic Surgery, University of Rome Tor Vergata, School of Medicine, Italy
    Eur Cell Mater 21:548-57. 2011
    ..several genes involved in tissue remodelling and bone development in patients with calcific tendinopathy of the rotator cuff. Biopsies from calcified and non-calcified areas were obtained from 10 patients (8 women and 2 men; average age:..
  40. ncbi Inflammatory and angiogenic mRNA levels are altered in a supraspinatus tendon overuse animal model
    Stephanie M Perry
    McKay Orthopaedic Research Laboratory, University of Pennsylvania, 424 Stemmler Hall, Philadelphia, PA 19104 6081, USA
    J Shoulder Elbow Surg 14:79S-83S. 2005
    Shoulder overuse injuries, especially those to the supraspinatus tendon of the rotator cuff, are common musculoskeletal disorders. Unfortunately, little is known about the disease etiology and pathogenesis...
  41. ncbi Rotator cuff repair healing influenced by platelet-rich plasma construct augmentation
    F Alan Barber
    Plano Orthopedic Sports Medicine and Spine Center, Plano, Texas, USA
    Arthroscopy 27:1029-35. 2011
    To assess the effect of platelet-rich plasma fibrin matrix (PRPFM) construct augmentation on postoperative tendon healing as determined by magnetic resonance imaging (MRI) and clinical outcome of arthroscopic rotator cuff repair.
  42. ncbi Arthroscopic rotator cuff repair using a suture bridge technique: is the repair integrity actually maintained?
    Nam Su Cho
    Shoulder and Elbow Clinic, Department of Orthopaedic Surgery, College of Medicine, Kyung Hee University, Seoul, Korea
    Am J Sports Med 39:2108-16. 2011
    ..Suture bridge repair has been recognized to have superior biomechanical characteristics, as shown in previous biomechanical studies. However, it is not clear whether the tendon heals better in vivo after suture bridge repair...
  43. ncbi Clinical tests for the diagnosis of rotator cuff disease
    Umile Giuseppe Longo
    Department of Orthopaedic and Trauma Surgery, Campus Bio Medico University, Trigoria, Rome, Italy
    Sports Med Arthrosc 19:266-78. 2011
    ..However, there is a lack of consensus on clinical assessment of patients with shoulder pain and suspected rotator cuff pathology. This review reports the diagnostic accuracy of clinical tests for rotator cuff pathology...
  44. pmc Full-thickness supraspinatus tears are associated with more synovial inflammation and tissue degeneration than partial-thickness tears
    Michael K Shindle
    Sports Medicine and Shoulder Service, Hospital for Special Surgery, New York, NY, USA
    J Shoulder Elbow Surg 20:917-27. 2011
    ..with synovial inflammation and tendon degeneration in patients who underwent shoulder arthroscopy for rotator cuff repair...
  45. ncbi Natural history of nonoperatively treated symptomatic rotator cuff tears in patients 60 years old or younger
    Ori Safran
    Department of Orthopedics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Am J Sports Med 39:710-4. 2011
    b>Rotator cuff tears are the most frequent tendon injury in the adult population. However, the natural history of nonoperatively treated full-thickness tears is poorly defined...
  46. ncbi Prognostic factors affecting anatomic outcome of rotator cuff repair and correlation with functional outcome
    Joo Han Oh
    Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea
    Arthroscopy 25:30-9. 2009
    To analyze the relationship between functional outcomes and postoperative cuff integrity (anatomic outcome), and to reveal the factors affecting outcomes of rotator cuff repair.
  47. ncbi Platelet rich plasma in arthroscopic rotator cuff repair: a prospective RCT study, 2-year follow-up
    Pietro Randelli
    Department of Scienze Medico Chirurgiche, University of Milano, IRCCS Policlinico San Donato, Milano, Italy
    J Shoulder Elbow Surg 20:518-28. 2011
    Local application of autologous platelet rich plasma (PRP) improves tendon healing in patients undergoing arthroscopic rotator cuff repair.
  48. ncbi The clinical and structural long-term results of open repair of massive tears of the rotator cuff
    Matthias A Zumstein
    Department of Orthopedics, University of Zurich, Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    J Bone Joint Surg Am 90:2423-31. 2008
    At a mean follow-up of 3.1 years, twenty-seven consecutive repairs of massive rotator cuff tears yielded good and excellent clinical results despite a retear rate of 37%...
  49. ncbi Use of the reverse shoulder prosthesis for the treatment of failed hemiarthroplasty in patients with glenohumeral arthritis and rotator cuff deficiency
    J C Levy
    Orthopaedic Institute at Holy Cross, Fort Lauderdale, Florida 33308, USA
    J Bone Joint Surg Br 89:189-95. 2007
    ..The primary procedure had been undertaken for glenohumeral arthritis associated with severe rotator cuff deficiency. Statistically significant improvements were seen in pain and functional outcome...
  50. ncbi Gender adjustment or stratification in discerning upper extremity musculoskeletal disorder risk?
    Barbara Silverstein
    Safety and Health Assessment and Research for Prevention SHARP Program, Washington State Department of Labor and Industries, PO Box 44330, Olympia, Washington, United States
    Scand J Work Environ Health 35:113-26. 2009
    The aim was to explore whether "adjustment" for gender masks important exposure differences between men and women in a study of rotator cuff syndrome (RCS) and carpal tunnel syndrome (CTS) and work exposures.
  51. ncbi A prospective randomized clinical trial comparing arthroscopic single- and double-row rotator cuff repair: magnetic resonance imaging and early clinical evaluation
    Robert T Burks
    University of Utah Orthopaedic Center, Salt Lake City, 84108, USA
    Am J Sports Med 37:674-82. 2009
    Double-row arthroscopic rotator cuff repair has become more popular, and some studies have shown better footprint coverage and improved biomechanics of the repair.
  52. ncbi Functional and structural outcome after arthroscopic full-thickness rotator cuff repair: single-row versus dual-row fixation
    Hiroyuki Sugaya
    Shoulder and Elbow Service, Funabashi Orthopedic Sports Medicine Center, Funabashi, Chiba, Japan
    Arthroscopy 21:1307-16. 2005
    The purpose of this study was to compare the functional as well as the structural outcomes of single-row and dual-row fixation after arthroscopic full-thickness rotator cuff repair.
  53. ncbi Cuff integrity after arthroscopic versus open rotator cuff repair: a prospective study
    Julie Bishop
    Columbus Bone, Joint and Hand Surgeons, Inc, Columbus, OH, USA
    J Shoulder Elbow Surg 15:290-9. 2006
    Arthroscopic rotator cuff repair (RCR) has been reported to have good clinical results but high retear rates by ultrasound...
  54. ncbi Surgically repaired massive rotator cuff tears: MRI of tendon integrity, muscle fatty degeneration, and muscle atrophy correlated with intraoperative and clinical findings
    J M Mellado
    Institut de Diagnostic per la Imatge, Hospital Universitari de Tarragona Joan XXIII, Carrer Doctor Mallafrè Guasch, 4, 43007 Tarragona, Spain
    AJR Am J Roentgenol 184:1456-63. 2005
    ..the clinical significance of tendon integrity, muscle fatty degeneration, and muscle atrophy in surgically repaired massive rotator cuff tears and to correlate these and other prognostic factors with intraoperative and clinical findings.
  55. ncbi Prospective evaluation of the effect of rotator cuff integrity on the outcome of open rotator cuff repairs
    Steven Klepps
    Montana Orthopedics and Sports Medicine, St Vincent s Hospital, Billings, Montana
    Am J Sports Med 32:1716-22. 2004
    Open rotator cuff repairs have led to excellent clinical results; however, several studies have linked postoperative structural integrity to patient outcomes...
  56. ncbi Reversal of suprascapular neuropathy following arthroscopic repair of massive supraspinatus and infraspinatus rotator cuff tears
    John G Costouros
    Harvard Shoulder Service, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Arthroscopy 23:1152-61. 2007
    ..The purpose of this study was to study the prevalence of suprascapular neuropathy (SSN) in the setting of massive rotator cuff tears and to determine if arthroscopic rotator cuff repair, even if partial, was associated with reversal of ..
  57. ncbi Arthroscopic tenotomy of the long head of the biceps in the treatment of rotator cuff tears: clinical and radiographic results of 307 cases
    Gilles Walch
    Department of Orthopaedic Surgery, Clinique Sainte Anne Lumière, Lyon, France
    J Shoulder Elbow Surg 14:238-46. 2005
    ..the objective, subjective, and radiographic results of arthroscopic biceps tenotomy in selected patients with rotator cuff tears...
  58. ncbi Biomechanical evaluation of arthroscopic rotator cuff stitches
    C Benjamin Ma
    The Hospital for Special Surgery, New York, NY 10021, USA
    J Bone Joint Surg Am 86:1211-6. 2004
    The suture configurations in arthroscopic rotator cuff repairs have been limited to simple and horizontal stitches. Recent objective evaluations have demonstrated high failure rates of arthroscopic repairs of rotator cuff tears...
  59. ncbi Diagnostic performance of MR arthrography after rotator cuff repair
    Sylvain R Duc
    Department of Radiology, University Hospital Balgrist, Forchstrasse 340, Zurich CH 8008, Switzerland
    AJR Am J Roentgenol 186:237-41. 2006
    The objective of this study was to investigate the diagnostic performance of MR arthrography after rotator cuff repair.
  60. ncbi Platelet-rich plasma and the upper extremity
    Allan Mishra
    Department of Orthopaedic Surgery, Menlo Medical Clinic, Stanford University Medical Center, 1300 Crane Street, Menlo Park, CA 94025, USA
    Hand Clin 28:481-91. 2012
    ..Clinical investigations have focused on the treatment of chronic lateral epicondylar tendinopathy and rotator cuff pathology. Multiple controlled studies support the use of PRP for chronic tennis elbow...
  61. ncbi Humeral insertion of the supraspinatus and infraspinatus. New anatomical findings regarding the footprint of the rotator cuff
    Tomoyuki Mochizuki
    Section of Orthopaedic Surgery, Division of Cartilage Regeneration, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    J Bone Joint Surg Am 90:962-9. 2008
    It is generally believed that the supraspinatus is the most commonly involved tendon in rotator cuff tears...
  62. ncbi A comparison of physical examinations with musculoskeletal ultrasound in the diagnosis of biceps long head tendinitis
    Hung Sheng Chen
    Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan
    Ultrasound Med Biol 37:1392-8. 2011
    ..Biceps tendon tendinitis was diagnosed with US in 39.1% of the patients and, of those, 55.3% had coexisting rotator cuff injury. The sensitivity and specificity of Yergason's test were 32% and 78%, respectively...
  63. ncbi Influence of age on the cell biological characteristics and the stimulation potential of male human tenocyte-like cells
    F Klatte-Schulz
    Julius Wolff Institute, Center for Musculoskeletal Surgery, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Eur Cell Mater 24:74-89. 2012
    The incidence of rotator cuff tears and recurrent defects positively correlate with patient age. However, this observation has never been analysed at the cellular level...
  64. ncbi Mini-open versus all-arthroscopic rotator cuff repair: comparison of the operative costs and the clinical outcomes
    Kamil Cagri Kose
    Department of Orthopaedics and Traumatology, Afyon Kocatepe University Faculty of Medicine, Afyon, Turkey
    Adv Ther 25:249-59. 2008
    b>Rotator cuff injury is one of the most frequently encountered problems of the shoulder in the daily practice of orthopaedic surgeons...
  65. ncbi The effects of aging on quantitative sonographic features of rotator cuff tendons
    Tung Yang Yu
    Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, Taiwan
    J Clin Ultrasound 40:471-8. 2012
    ..The purpose of the current study was to measure the changes in thickness and echogenicity that result from aging of the rotator cuff and long head of the biceps tendons.
  66. ncbi A prospective therapeutic comparison of simple suture repairs to massive cuff stitch repairs for treatment of small- and medium-sized rotator cuff tears
    Sang Hun Ko
    Department of Orthopedic Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea
    Arthroscopy 25:583-9, 589.e1-4. 2009
    The purpose of this study was to compare the massive cuff stitch (MCS) with the simple stitch in terms of integrity at 2 years after surgery when used to repair small-sized to medium-sized full-thickness rotator cuff tears.
  67. ncbi Bone marrow-derived mesenchymal stem cells obtained during arthroscopic rotator cuff repair surgery show potential for tendon cell differentiation after treatment with insulin
    Augustus D Mazzocca
    Department of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut 06034, USA
    Arthroscopy 27:1459-71. 2011
    ....
  68. ncbi Does platelet-rich plasma accelerate recovery after rotator cuff repair? A prospective cohort study
    Chris Hyunchul Jo
    Department of Orthopedic Surgery, SMG SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea
    Am J Sports Med 39:2082-90. 2011
    Platelet-rich plasma (PRP) has been recently used to enhance and accelerate the healing of musculoskeletal injuries and diseases, but evidence is still lacking, especially on its effects after rotator cuff repair.
  69. ncbi A comparison of single-versus double-row suture anchor techniques in a simulated repair of the rotator cuff: an experimental study in rabbits
    M Ozbaydar
    Department of Orthopaedics and Traumatology, Okmeydani Teaching Hospital, 34387, Okmeydani, Istanbul, Turkey
    J Bone Joint Surg Br 90:1386-91. 2008
    ..changes in the biomechanical properties of single-and double-row repair of a simulated acute tear of the rotator cuff in rabbits to determine the effect of the fixation techniques on the healing process...
  70. ncbi The geometric classification of rotator cuff tears: a system linking tear pattern to treatment and prognosis
    James Davidson
    Canyon Orthopaedic Surgeons, Phoenix, Arizona, USA
    Arthroscopy 26:417-24. 2010
    ..There is no current standard classification for rotator cuff tears. Authors and practicing orthopaedists use a variety of descriptions when communicating about cuff tears...
  71. pmc Location and initiation of degenerative rotator cuff tears: an analysis of three hundred and sixty shoulders
    H Mike Kim
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Bone Joint Surg Am 92:1088-96. 2010
    It has been theorized that degenerative rotator cuff tears most commonly involve the supraspinatus tendon, initiating at the anterior portion of the supraspinatus insertion and propagating posteriorly...
  72. ncbi Contribution of oxidative stress to the degeneration of rotator cuff entheses
    Daichi Morikawa
    Department of Advanced Aging Medicine, Chiba University Graduate School of Medicine, Chiba, Japan Department of Orthopaedics, Juntendo University Graduate School of Medicine, Tokyo, Japan
    J Shoulder Elbow Surg 23:628-35. 2014
    b>Rotator cuff degeneration is one of the multiple factors that lead to rotator cuff tears; however, the precise mechanism of such degeneration still remains unclear...
  73. ncbi Effect of proximal humeral fractures on the age-specific prevalence of rotator cuff tears
    Christian Bahrs
    BG Trauma Center, Hospital for Traumatology and Reconstructive Surgery, Eberhard Karls University, Tuebingen, Germany
    J Trauma 69:901-6. 2010
    This study examined the effect of proximal humeral fractures on the age- and shoulder-specific prevalence of rotator cuff tears (RCTs) as well as the association with fracture severity, patient age, and clinical outcome.
  74. pmc Lifestyle and metabolic factors in relation to shoulder pain and rotator cuff tendinitis: a population-based study
    Martti Rechardt
    Centre of Expertise for Health and Work Ability, Finnish Institute of Occupational Health, Finland
    BMC Musculoskelet Disord 11:165. 2010
    ..The purpose of this study was to assess the associations of lifestyle factors, metabolic factors and carotid intima-media thickness with shoulder pain and chronic (> 3 months) rotator cuff tendinitis.
  75. ncbi The shoulder in baseball pitching: biomechanics and related injuries-part 2
    Samuel S Park
    NYU Hospital for Joint Diseases, Department of Orthopaedic Surgery, New York, New York 10003, USA
    Bull Hosp Jt Dis 61:80-8. 2002
    ..Through rehabilitation, the dedicated athlete can often return to the pitching mound at his previous level of performance...
  76. ncbi Characterization of tendon cell cultures of the human rotator cuff
    S Pauly
    Julius Wolff Institut, Center for Musculoskeletal Surgery, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur Cell Mater 20:84-97. 2010
    b>Rotator cuff tears are common soft tissue injuries of the musculoskeletal system that heal by formation of repair tissue and may lead to high retear rates and joint dysfunction...
  77. ncbi Prevalence of rotator cuff tear in paraplegic patients compared with controls
    Michael Akbar
    Department of Orthopaedic Surgery and Rehabilitation Medicine, University of Heidelberg, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany
    J Bone Joint Surg Am 92:23-30. 2010
    ....
  78. ncbi Retear patterns after arthroscopic rotator cuff repair: single-row versus suture bridge technique
    Nam Su Cho
    Department of Orthopaedic Surgery, Kyung Hee University School of Medicine, Dongdaemun Gu, Seoul 130 702, Korea
    Am J Sports Med 38:664-71. 2010
    A subset of patients is often seen with an unusual pattern of tendon failure after arthroscopic rotator cuff repair using a suture bridge technique.
  79. pmc Factors related to successful outcome of conservative treatment for rotator cuff tears
    Minoru Tanaka
    Tohoku Rosai Hospital, and Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan
    Ups J Med Sci 115:193-200. 2010
    Much controversy exists as to the management of full-thickness tears of the rotator cuff. Not all patients with rotator cuff tears require surgical treatment...
  80. pmc Open versus two forms of arthroscopic rotator cuff repair
    Neal L Millar
    Department of Orthopaedic Surgery, Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, 4 10 South Street, Kogarah, Sydney, NSW 2217, Australia
    Clin Orthop Relat Res 467:966-78. 2009
    ..We compared the clinical and structural outcomes of three different forms of rotator cuff repair with up to 24 months' followup...
  81. ncbi Comparative analysis of single-row versus double-row repair of rotator cuff tears
    William T Pennington
    The Orthopedic Institute of Wisconsin, Midwest Orthopedic Specialty Hospital, 3111 W Rawson Ave, Franklin, WI 53132, U S A
    Arthroscopy 26:1419-26. 2010
    ..Our goal in this analysis was to compare clinical outcomes and radiographic healing rates of double-row (DR) transosseous-equivalent versus single-row (SR) Mason-Allen configuration (MAC) arthroscopic repair techniques...
  82. ncbi Range of motion limitation after rotator cuff repair
    Surena Namdari
    The Department of Orthopaedic Surgery, The University of Pennsylvania, Philadelphia, PA, USA
    J Shoulder Elbow Surg 19:290-6. 2010
    This study was conducted to identify preoperative factors correlating with limited motion after rotator cuff repair (RCR) and to evaluate the affect of loss of motion on outcome...
  83. ncbi Ultrasound detection of rotator cuff tears: observer agreement related to increasing experience
    Matthieu J C M Rutten
    Department of Radiology, Jeroen Bosch Hospital, Nieuwstraat 34, 5211 NL s Hertogenbosch, The Netherlands
    AJR Am J Roentgenol 195:W440-6. 2010
    Ultrasound of the rotator cuff is considered to be operator-dependent with its accuracy being related to the operator's level of experience...
  84. ncbi Reverse shoulder arthroplasty for the treatment of irreparable rotator cuff tear without glenohumeral arthritis
    Philip Mulieri
    Florida Orthopaedic Institute, 13020 North Telecom Parkway, Tampa, FL 33637, USA
    J Bone Joint Surg Am 92:2544-56. 2010
    The purpose of the present study was to evaluate the indications for, and outcomes of, reverse shoulder arthroplasty in patients with massive rotator cuff tears but without glenohumeral arthritis.
  85. pmc Effect of fiber distribution and realignment on the nonlinear and inhomogeneous mechanical properties of human supraspinatus tendon under longitudinal tensile loading
    Spencer P Lake
    McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, 424 Stemmler Hall, Philadelphia, Pennsylvania 19104 6081
    J Orthop Res 27:1596-602. 2009
    ..The supraspinatus tendon (SST) of the rotator cuff is of particular interest for investigation due to its complex mechanical environment and corresponding ..
  86. ncbi Minimal clinically important differences (MCID) and patient acceptable symptomatic state (PASS) for visual analog scales (VAS) measuring pain in patients treated for rotator cuff disease
    Robert Z Tashjian
    Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
    J Shoulder Elbow Surg 18:927-32. 2009
    ..The PASS is the score below which patients consider themselves well. The purpose of this study was to determine the MCID and PASS for a visual analog scale (VAS) measuring pain in patients treated for rotator cuff disease.
  87. ncbi Platelet-rich plasma: current concepts and application in sports medicine
    Michael P Hall
    Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY 10003, USA
    J Am Acad Orthop Surg 17:602-8. 2009
    ..Its use in surgery to augment rotator cuff and Achilles tendon repair has also been reported...
  88. pmc Internal rotation and scapular position differences: a comparison of collegiate and high school baseball players
    Stephen J Thomas
    University of Delaware, Newark, DE, USA
    J Athl Train 45:44-50. 2010
    Conditions such as labral and rotator cuff injuries have been linked with decreases in glenohumeral internal-rotation and increases in external-rotation motion...
  89. ncbi Apoptosis in rotator cuff tendonopathy
    Jun Yuan
    Orthopaedic Research Institute, St George Hospital Campus, 4 10 South Street, University of New, South Wales, Sydney, NSW 2217, Australia
    J Orthop Res 20:1372-9. 2002
    ..of this study was to investigate the involvement of apoptosis (programmed cell death) in the pathogenesis of rotator cuff disorders...
  90. ncbi Deficits in shoulder function and general health associated with sixteen common shoulder diagnoses: a study of 2674 patients
    Mauricio Largacha
    Department of Orthopaedics and Sports Medicine, University of Washington Medical Center, 1959 NE Pacific Street, Seattle, WA 98195, USA
    J Shoulder Elbow Surg 15:30-9. 2006
    ..The magnitude of these deficits correlated significantly with gender and diagnosis but not with age...
  91. ncbi Part I: Footprint contact characteristics for a transosseous-equivalent rotator cuff repair technique compared with a double-row repair technique
    Maxwell C Park
    Kerlan Jobe Orthopaedic Clinic, Los Angeles, CA, USA
    J Shoulder Elbow Surg 16:461-8. 2007
    b>Rotator cuff repair via transosseous tunnels can improve footprint contact area and pressure when compared with suture anchor techniques. A double-row technique has been used clinically to improve footprint coverage by a repaired tendon...
  92. ncbi Total cost and operating room time comparison of rotator cuff repair techniques at low, intermediate, and high volume centers: mini-open versus all-arthroscopic
    R Sean Churchill
    Aurora Advanced Healthcare, Milwaukee, WI 53209, USA
    J Shoulder Elbow Surg 19:716-21. 2010
    ..objective of this study was to determine mean cost and operative time differences between mini-open and all-arthroscopic rotator cuff repair techniques at surgical centers of low, intermediate, and high annual rotator cuff repair volume.
  93. ncbi Development of the supraspinatus tendon-to-bone insertion: localized expression of extracellular matrix and growth factor genes
    Leesa Galatz
    Washington University Orthopaedics, Barnes Jewish Hospital, Campus Box 8233, 660 S Euclid Avenue, St Louis, Missouri 63110, USA
    J Orthop Res 25:1621-8. 2007
    The adult healing response of the rotator cuff tendon-to-bone insertion site differs from the ordered process of insertion site development...
  94. pmc Disability and satisfaction after rotator cuff decompression or repair: a sex and gender analysis
    Helen Razmjou
    Holland Orthopaedic and Arthritic Centre, Sunnybrook Health Sciences Centre, Toronto, Canada
    BMC Musculoskelet Disord 12:66. 2011
    ..and societal factors on disability would potentially identify existing differences between men and women with rotator cuff pathology which would help to provide suggestions for better models of care...
  95. ncbi Rapid isolation of human stem cells (connective tissue progenitor cells) from the proximal humerus during arthroscopic rotator cuff surgery
    Augustus D Mazzocca
    University of Connecticut, Department of Orthopaedic Surgery, Farmington, CT 06034, USA
    Am J Sports Med 38:1438-47. 2010
    ..Bone-to-tendon healing in the shoulder can be unpredictable. Biologic augmentation, through the implementation of adult mesenchymal stem cells, may improve this healing process...
  96. ncbi Factors affecting rotator cuff healing after arthroscopic repair: osteoporosis as one of the independent risk factors
    Seok Won Chung
    Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Korea
    Am J Sports Med 39:2099-107. 2011
    The prognostic factors associated with structural outcome after arthroscopic rotator cuff repair have not yet been fully determined.
  97. ncbi Extracellular matrix scaffold devices for rotator cuff repair
    Kathleen A Derwin
    Department of Biomedical Engineering, Orthopaedic Research Center, Cleveland Clinic, Cleveland, OH 44195, USA
    J Shoulder Elbow Surg 19:467-76. 2010
    b>Rotator cuff tears affect 40% or more of those over age 60, and the repair failure rate of large to massive tears ranges from 20 to 90%...
  98. ncbi Arthroscopic knots and strength sutures for rotator cuff repair
    Umile Giuseppe Longo
    Department of Orthopaedic and Trauma Surgery, Campus Biomedico University, Trigoria, Rome, Italy
    Sports Med Arthrosc 19:251-65. 2011
    Most arthroscopic rotator cuff reconstruction techniques require a method of securing the tendon to the bone to obtain a stable construct...
  99. ncbi Most clinical tests cannot accurately diagnose rotator cuff pathology: a systematic review
    Phillip C Hughes
    School of Physiotherapy, La Trobe University, Bundoora, VIC 3086, Australia
    Aust J Physiother 54:159-70. 2008
    Do clinical tests accurately diagnose rotator cuff pathology?
  100. pmc Rotator cuff repair augmentation in a canine model with use of a woven poly-L-lactide device
    Kathleen A Derwin
    Department of Biomedical Engineering, ND2 20, Cleveland Clinic, Cleveland, OH 44122, USA
    J Bone Joint Surg Am 91:1159-71. 2009
    Despite advances in surgical treatment options, failure rates of rotator cuff repair have continued to range from 20% to 90%...
  101. ncbi The low-profile Roman bridge technique for knotless double-row repair of the rotator cuff
    Umile Giuseppe Longo
    Department of Orthopaedic and Trauma Surgery, Campus Biomedico University, Via Alvaro del Portillo, 200, Trigoria, Rome, 00128, Italy
    Arch Orthop Trauma Surg 131:357-61. 2011
    ..been developed to increase the tendon-bone contact area, reconstituting a more anatomic configuration of the rotator cuff footprint and providing a better environment for tendon healing...

Research Grants65

  1. A Biomechanical Study of Work-Related Shoulder Disorder
    ANDREW ROBERT KARDUNA; Fiscal Year: 2010
    ..injuries may initially manifest as diffuse shoulder pain, however, the vast majority reflect pathology of the rotator cuff tendons in the subacromial space...
  2. Functional tissue engineering of tendon
    Stavros Thomopoulos; Fiscal Year: 2003
    ..The tendons of shoulder joint (i.e., the rotator cuff) are particularly susceptible to injury, with tears often occurring near the tendon to bone interface after ..
  3. Aligned Tendon or Ligament Derived Matrix Nanoscaffolds for Rotator Cuff Repair
    Dianne Little; Fiscal Year: 2013
    ..and then an R01 submission in year 4 to evaluate the proposed scaffolds in a large animal model of chronic rotator cuff tear, and expects to publish three manuscripts resulting from this initial work...
  4. Use Of Adipose Derived Stem Cells For Engineering Of Ligament Tissue
    David McAllister; Fiscal Year: 2012
    ..These problems include shoulder (rotator cuff) and knee (quadriceps and patellar) tendon ruptures, which are also common in the VA patient population...
  5. Soft Tissue Compression Risk in Rotator Cuff Disease Development
    PAULA MARIE LUDEWIG; Fiscal Year: 2013
    ..b>Rotator cuff pathologies have up to 50% prevalence rates across several populations including persons with spinal cord ..
  6. Rotator cuff repair using hyaluronan enriched fascia extracellular matrix
    KATHLEEN ANNE DERWIN; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Rotator cuff tears affect 40% or more of those over age 60 and cost the US economy approximately $3 billion per year...
  7. Rotator Cuff Degeneration and Repair
    Stavros Thomopoulos; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The rotator cuff muscles of the shoulder provide stability and motion at the glenohumeral joint...
  8. Determining the Genetic Basis of Rotator Cuff Disease
    Robert Z Tashjian; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Rotator cuff disease is prevalent in the United States, with over 17 million individuals affected and accounting for over 3.8 million annual physician visits...
  9. Expandable Shape-Memory Polymers for Suture Anchors
    Christopher M Yakacki; Fiscal Year: 2011
    ..b>Rotator cuff repairs are common surgical procedures involving suture anchors to reduce pain and restore use to an injured ..
  10. Cross-scale interactions between mineral and collagen for tendon-bone attachment
    Stavros Thomopoulos; Fiscal Year: 2013
    ..A large percentage of these repairs have poor outcomes;for example, up to 94% of surgical rotator cuff repairs fail...
  11. Mechanobiology of Rotator Cuff Development
    Stavros Thomopoulos; Fiscal Year: 2013
    ..These conditions are thought to be a result of abnormal rotator cuff muscle loading across the developing joint...
  12. Shoulder Pain in Spinal Cord Injury (SCI): A Longitudinal Study
    Sara J Mulroy; Fiscal Year: 2010
    ..Additionally, an imbalance in the strength of the rotator cuff muscles has been documented in individuals with shoulder pain after SCI...
  13. Nanofiber Scaffolds with Gradations in Mineral Content for Rotator Cuff Repair
    Younan Xia; Fiscal Year: 2013
    ..Our goal is to design, fabricate, and validate novel nanostructures for use in the surgical repair of rotator cuff tears to restore the torn tendon to its bony insertion...
  14. The Pathophysiology of Rotator Cuff Tendon Injury and Healing in the Presence of
    Stephen John Thomas; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Rotator cuff tendon tears are a widespread orthopedic problem that often requires surgical repair to eliminate pain and restore function...
  15. Rotator Cuff Tears: Optimizing Diagnosis and Treatment Strategies
    Nitin B Jain; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Rotator cuff tears are the most common cause of shoulder disability and pain accounting for 4.5 million physician visits and 75,000 surgeries annually...
  16. The Physiological Basis of Rotator Cuff Muscle Rehabilitation
    SAMUEL RICHARD WARD; Fiscal Year: 2013
    ..The shoulder is the most common site of tendinopathy, with 30% of individuals over 60 years of age experiencing rotator cuff-related injuries...
  17. Structure Function Relationships at the Tendon to Bone Insertion Site
    Stavros Thomopoulos; Fiscal Year: 2010
    ..1 Injuries to the soft tissues often require surgical repair and tendon-to-bone healing (e.g., rotator cuff repair2,3, anterior cruciate ligament reconstruction4,5, flexor tendon avulsion6)...
  18. Enhanced tendon to bone healing
    Stavros Thomopoulos; Fiscal Year: 2010
    ..At the rotator cuff, where there are no repair techniques that are immune from recurrent tears, short to mid term failure rates ..
  19. Muscle function and compensation following rotator cuff tear in older adults
    MEGHAN ELISE VIDT; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Approximately 20-50% of older adults (age >65 years) are living with a rotator cuff tear, and this number increases with advanced age...
  20. Hyaluronan Enriched Fascia ECM for Rotator Cuff Repair
    LIKANG CHIN; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Rotator cuff injury is a debilitating health concern that affects more than 40% of our aging population and costs the US economy $3 billion per year...
  21. Models to predict protein biomaterial performance
    Joyce Y Wong; Fiscal Year: 2013
    ..applications as the focus due to the generic needs in this field, such as for the anterior cruciate ligament, rotator cuff, bladder slings, hernia meshes, blood vessels, nerve guides and other tissues...
  22. Multiscale structural and mechanical analysis of soft tissue under complex loads
    SPENCER PARK LAKE; Fiscal Year: 2012
    ..One example is the supraspinatus tendon (SST) of the rotator cuff, which has a high rate of degeneration and injury that may be due to the complex loading environment of the ..
  23. Molecular pathophysiology of massive rotator cuff tears
    Brian Feeley; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Rotator cuff tears (RCTs) are an extremely common cause of shoulder pain and disability. Up to 20% of patients greater than the age of 50 years of age have evidence of a rotator cuff tear...
  24. Engineering Tendon Grafts for Better Outcomes
    Chunfeng Zhao; Fiscal Year: 2013
    ..to study other applications of tendon grafting where adhesion prevention is important, such as for the rotator cuff. PUBLIC HEALTH RELEVANCE: The restoration of normal hand function is crucial after flexor tendon injuries, and ..
  25. Muscle Triglyceride Metabolism Core Center
    Richard L Lieber; Fiscal Year: 2010
    ..has become obvious based on the clinical findings of intramuscular fat deposition in diabetes, secondary to rotator cuff tear, and in atrophied lumbar musculature...
  26. A tissue specific approach to enhance tendon repair
    James H C Wang; Fiscal Year: 2013
    ..Moreover, we will use the proven tendon injury mode in this study as a "stepping-stone" for further studying healing problems of other tendon types, including flexor and rotator cuff tendons.
  27. Efficacy Of Physical Therapy And Surgical Repair For Treating Rotator Cuff Tears
    Michael J Bey; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Rotator cuff tears are common, affecting 50% or more of the population over age 60. This condition in painful and often results in long-term shoulder disability even after surgical repair...
  28. An Improved Lever Drive Wheelchair Transmission
    Steve Green; Fiscal Year: 2003
    ..Of these, it is estimated that one half will eventually develop CTS and/or shoulder injuries such as rotator cuff tears...
  29. An Improved Lever Drive Wheelchair Transmission
    Steve Green; Fiscal Year: 2001
    ..Of those, it is estimated that one half will eventually develop CTS and/or shoulder injuries such as rotator cuff tears...
  30. THE BIOMECHANICS OF OCCUPATIONAL SHOULDER INJURIES
    Andrew Karduna; Fiscal Year: 2001
    ..motion is associated with muscle fatigue and abnormal shoulder motion, which in turn may lead to damage of the rotator cuff musculature...
  31. Fabrication and characterization of constructs from decellularized tendon
    Qiaobing Xu; Fiscal Year: 2013
    ..These results will provide useful instruction for next step biomedical applications, including artificial blood vessel, nerve conduits or patches for rotator cuff repair.
  32. Combination of Nanofiber Scaffolds with Gradations in Fiber Organization and Mine
    Franklin D Shuler; Fiscal Year: 2013
    ..Scaffolds with Gradations in Fiber Organization and Mineral Content and Adipose-derived Stem Cells for Rotator Cuff Injury Repair" addresses the challenge in engineering a tissue construct to repair rotator cuff injury...
  33. Mechanisms of Joint Damage Following Tendon Injury
    Louis J Soslowsky; Fiscal Year: 2013
    ..The parent grant uses an established rat rotator cuff injury model to study the biological and mechanical properties of the cartilage and intact tendons after a ..
  34. Asymtomatic Cuff Tears: A Model for Pain Development
    Ken Yamaguchi; Fiscal Year: 2013
    ..renewal application is designed to obtain extended follow-up of a unique cohort of asymptomatic patients with rotator cuff tears from which substantial and encouraging data has been obtained...
  35. BIOMECHANICS OF THE ROTATOR CUFF
    Kai Nan An; Fiscal Year: 1999
    ..from the Applicant's Abstract): It has been recognized by clinical experience and laboratory study that the rotator cuff muscle tendon complex has a functionally important role in generating load and maintaining stability of the ..
  36. AUTOMATIC CORRECTION OF MOTION ARTIFACTS IN MR IMAGES
    Armando Manduca; Fiscal Year: 2001
    ..metrics, and (3) implementation and validation of autocorrection in five specific clinical applications: rotator cuff imaging, spine imaging, cerebral and renal angiography, 3D head imaging, and diffusion imaging...
  37. Biphasic Nanofiber-based Scaffold for Tendon-to-Bone Integration
    Helen Lu; Fiscal Year: 2009
    ..Specifically, we focus on the challenge of tendon-to-bone integration for Rotator Cuff repair and augmentation...
  38. Structure-Function of the Glenohumeral Joint
    Richard Hughes; Fiscal Year: 2006
    ..of the glenoid in the plane of the scapula, which we term "glenoid inclination," affects the ability of the rotator cuff muscles to prevent superior humeral head translation...
  39. ETIOLOGIC FACTORS FOR TENDON DEGENERATION
    LOUIS SOSLOWSKY; Fiscal Year: 2004
    ..The rotator cuff tendons are used as a paradigm for overuse injuries in tendons in general...
  40. A Repositionable Tissue Anchor for Osteoporortic Bone
    DANIEL KELSCH; Fiscal Year: 2004
    ..Phase I confirmation of feasibility, the goal of the Phase II work is the specific product development of the rotator cuff repair anchor, followed by design modification for a diverse product line of anchor products...
  41. "In Vitro Mechanical Stimulation to Enhance Tendon Repair"
    David Butler; Fiscal Year: 2009
    ..biological constructs to reduce pain and stiffness and to provide grafts for revision surgery;repairing large rotator cuff tears and augmenting ligament reconstructions;and repairing chronic degenerative tendon injuries...
  42. Arthroscopic rotator cuff repair device
    Simon Williams; Fiscal Year: 2006
    ..by applicant): The objective of this research is to determine the feasibility of developing a new device for rotator cuff repair that can be used in an arthroscopic procedure...
  43. Human Tissue Engineered Matrix Constructs for Repair
    Anthony Ratcliffe; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Surgical repair of rotator cuff injury is a common procedure, however structural failure of the surgical repair is a common complication of the surgery, and may be a frequent occurrence...
  44. Human Tissue Engineered Matrix Constructs for Repair
    Anthony Ratcliffe; Fiscal Year: 2005
    ..engineering approach to develop a construct that will enhance the surgical repair of tendons, in particular the rotator cuff. The objective of this Phase I application is to determine the feasibility of producing tissue engineered ..
  45. A REPOSITIONABLE TISSUE ANCHOR FOR OSTEOPOROTIC BONE
    James Price; Fiscal Year: 2001
    ..The repositioning effect on fixation strength will also be investigated for these anchors. PROPOSED COMMERCIAL APPLICATION: Surgeries involving attachment of ligament or tendon to bone Ex. rotator cuff, SLAP lesion, Bankart repairs.
  46. Acute Rotator Cuff Tendon Changes Associated with Wheelchair Propulsion
    Michael Boninger; Fiscal Year: 2008
    ..The most common diagnoses related to musculoskeletal shoulder pain in chronic SCI are impingement syndrome and rotator cuff disease...
  47. Clinically relevant large animal model of rotator cuff injury and repair
    Kathleen Derwin; Fiscal Year: 2007
    ..DESCRIPTION (provided by applicant): Project Summary: In the human condition, a chronic, full thickness rotator cuff tear without surgical repair results in a permanent defect in the tendon, and the unloaded muscle progresses to ..
  48. A role for intrinsic tendon cells in overuse injury
    Kathleen Derwin; Fiscal Year: 2005
    ..A role for intrinsic tendon cells in the pathogenesis of tendon overuse injury would be implied by a lower damage threshold in vital tendon. ..
  49. Cleveland Clinic Orthopaedic Research Training Grant
    JOSEPH IANNOTTI; Fiscal Year: 2008
    ..abstract_text> ..
  50. The Interaction of Mechanical Load and Inflammation in Tendon-Bone Healing
    Scott A Rodeo; Fiscal Year: 2010
    ..The results of our studies will allow a scientific basis for the design of post- operative rehabilitation prescription. ..
  51. INTERVENTION EFFECTIVENESS IN NURSING HOMES
    Barbara Silverstein; Fiscal Year: 2001
    ....
  52. Basic Science of Tendon To Bone Healing
    Asheesh Bedi; Fiscal Year: 2008
    ..reconstructive surgical procedures, such as anterior cruciate ligament (ACL) reconstruction in the knee and rotator cuff repair, require healing between a tendon and bone...
  53. Subacromial space reductions in rotator cuff disease: Effects on soft tissue
    PAULA LUDEWIG; Fiscal Year: 2008
    ..b>Rotator cuff pathologies have up to 50% prevalence rates across several populations including persons with spinal cord ..
  54. QUANTIFICATION OF FACTORS LEADING TO VEIN GRAFT FAILURE
    Daniel Leotta; Fiscal Year: 2004
    ..By developing methods to detect the early indicators of impending failure, this project offers the opportunity to extend the useful life of the grafts by permitting early treatment of the lesions. ..
  55. Biomechanically Based Shoulder Rehabilitation Strategies
    PAULA LUDEWIG; Fiscal Year: 2007
    ..abstract_text> ..
  56. TENDON TO BONE HEALING--ROLE OF MECHANICAL ENVIRONMENT
    Gerald Williams; Fiscal Year: 2003
    ..to provide insight regarding an appropriate post-operative rehabilitation protocol following, for example, a rotator cuff repair...
  57. Force and Measurement Device - Phase II
    Rory Cooper; Fiscal Year: 2003
    ..g. playgrounds, parks, etc.). ..
  58. Adeno-associated virus for IGF-I cartilage gene therapy
    Alan Nixon; Fiscal Year: 2003
    ..abstract_text> ..
  59. Enhancing Recovery of Muscle after Rotator Cuff Repair
    Elisabeth Barton; Fiscal Year: 2006
    ..Damage to the rotator cuff tendons can occur with overuse or by direct trauma...
  60. GLENOHUMERAL JOINT STABILITY: ROLE OF THE CAPSULE
    RICHARD DEBSKI; Fiscal Year: 2007
    ..with unsatisfactory results in 20-25% of patients due to loss of range of motion, recurrent instability, rotator cuff damage, or osteoarthritis...
  61. Real-Time MRI and 3D Modeling: Development and Application to Patellofemoral Pain
    GARRY GOLD; Fiscal Year: 2008
    ..The novel imaging and biomechanical modeling techniques developed in this research will be used to improve the diagnosis and treatment of a range of musculoskeletal disorders. ..
  62. Rotator cuff tendon to bone insertion site healing
    Louis J Soslowsky; Fiscal Year: 2010
    The ability of rotator cuff tendons to heal back to bone following injury is limited, and failure of surgically repaired rotator cuff tears in humans has been reported in 20-70% of cases...
  63. Tendon Strains in Rotator Cuff Injury/Repair Using MRI
    LOUIS SOSLOWSKY; Fiscal Year: 2007
    b>Rotator cuff tears are an extremely common injury, representing a significant source of pain and disability...