horns

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Top Publications

  1. ncbi Calf response to caustic paste and hot-iron dehorning using sedation with and without local anesthetic
    K J Vickers
    Animal Welfare Program, Faculty of Agricultural Sciences, The University of British Columbia, Vancouver V6T 1Z4, Canada
    J Dairy Sci 88:1454-9. 2005
  2. ncbi Genome-wide association mapping identifies the genetic basis of discrete and quantitative variation in sexual weaponry in a wild sheep population
    Susan E Johnston
    Department of Animal and Plant Sciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK
    Mol Ecol 20:2555-66. 2011
  3. pmc A 3.7 Mb deletion encompassing ZEB2 causes a novel polled and multisystemic syndrome in the progeny of a somatic mosaic bull
    Aurélien Capitan
    INRA, UMR1313 Genetique Animale et Biologie Integrative, Jouy en Josas, France
    PLoS ONE 7:e49084. 2012
  4. ncbi Costs and the diversification of exaggerated animal structures
    D J Emlen
    Division of Biological Sciences, University of Montana, Missoula, MT 59812 1002, USA
    Science 291:1534-6. 2001
  5. pmc A newly described bovine type 2 scurs syndrome segregates with a frame-shift mutation in TWIST1
    Aurélien Capitan
    Unité Mixte de Recherche 1313 Génétique Animale et Biologie Intégrative, Institut National de la Recherche Agronomique, Jouy en Josas, France
    PLoS ONE 6:e22242. 2011
  6. pmc Differential recruitment of limb patterning genes during development and diversification of beetle horns
    Armin P Moczek
    Department of Biology, Indiana University, 915 East Third Street, Myers Hall 150, Bloomington, IN 47405 7107, USA
    Proc Natl Acad Sci U S A 106:8992-7. 2009
  7. pmc Assessment of behavioral changes associated with oral meloxicam administration at time of dehorning in calves using a remote triangulation device and accelerometers
    Miles E Theurer
    Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, USA
    BMC Vet Res 8:48. 2012
  8. ncbi The effect of meloxicam on behavior and pain sensitivity of dairy calves following cautery dehorning with a local anesthetic
    A Heinrich
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada, N1G 2W1
    J Dairy Sci 93:2450-7. 2010
  9. pmc Pangolin expression influences the development of a morphological novelty: beetle horns
    Bethany R Wasik
    Department of Biology, Indiana University, Bloomington, Indiana, USA
    Genesis 50:404-14. 2012
  10. ncbi Live fast, die young: trade-offs between fitness components and sexually antagonistic selection on weaponry in Soay sheep
    Matthew R Robinson
    Institute of Evolutionary Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, United Kingdom
    Evolution 60:2168-81. 2006

Detail Information

Publications227 found, 100 shown here

  1. ncbi Calf response to caustic paste and hot-iron dehorning using sedation with and without local anesthetic
    K J Vickers
    Animal Welfare Program, Faculty of Agricultural Sciences, The University of British Columbia, Vancouver V6T 1Z4, Canada
    J Dairy Sci 88:1454-9. 2005
    ..These results indicate that dehorning with caustic paste combined with a sedative results in less pain to calves than dehorning with a hot iron combined with a sedative and a local anesthetic...
  2. ncbi Genome-wide association mapping identifies the genetic basis of discrete and quantitative variation in sexual weaponry in a wild sheep population
    Susan E Johnston
    Department of Animal and Plant Sciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK
    Mol Ecol 20:2555-66. 2011
    ..aries) have an inherited polymorphism for horn morphology in both sexes, controlled by a single autosomal locus, Horns. The majority of males have large normal horns, but a small number have vestigial, deformed horns, known as scurs; ..
  3. pmc A 3.7 Mb deletion encompassing ZEB2 causes a novel polled and multisystemic syndrome in the progeny of a somatic mosaic bull
    Aurélien Capitan
    INRA, UMR1313 Genetique Animale et Biologie Integrative, Jouy en Josas, France
    PLoS ONE 7:e49084. 2012
    ..Its clinical spectrum includes polledness (complete agenesis of horns), facial dysmorphism, growth delay, chronic diarrhea, premature ovarian failure, and variable neurological and ..
  4. ncbi Costs and the diversification of exaggerated animal structures
    D J Emlen
    Division of Biological Sciences, University of Montana, Missoula, MT 59812 1002, USA
    Science 291:1534-6. 2001
    ..In beetles, production of horns reduces the size of neighboring morphological structures (antennae, eyes, or wings, depending on the location of ..
  5. pmc A newly described bovine type 2 scurs syndrome segregates with a frame-shift mutation in TWIST1
    Aurélien Capitan
    Unité Mixte de Recherche 1313 Génétique Animale et Biologie Intégrative, Institut National de la Recherche Agronomique, Jouy en Josas, France
    PLoS ONE 6:e22242. 2011
    ..In conclusion, this first report on the identification of a potential causal mutation affecting horn development in cattle offers a unique opportunity to better understand horn ontogenesis...
  6. pmc Differential recruitment of limb patterning genes during development and diversification of beetle horns
    Armin P Moczek
    Department of Biology, Indiana University, 915 East Third Street, Myers Hall 150, Bloomington, IN 47405 7107, USA
    Proc Natl Acad Sci U S A 106:8992-7. 2009
    ..Here we explore the developmental genetic regulation of beetle horns, a class of traits that lacks obvious homology to traits in other insects...
  7. pmc Assessment of behavioral changes associated with oral meloxicam administration at time of dehorning in calves using a remote triangulation device and accelerometers
    Miles E Theurer
    Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, USA
    BMC Vet Res 8:48. 2012
    ..Accelerometers monitored lying behavior and the remote triangulation device was used to monitor each calf's movement within the pen...
  8. ncbi The effect of meloxicam on behavior and pain sensitivity of dairy calves following cautery dehorning with a local anesthetic
    A Heinrich
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada, N1G 2W1
    J Dairy Sci 93:2450-7. 2010
    ..62+/-0.13 kg of force and 2.13+/-0.15 kg of force for control and meloxicam calves, respectively). Changes in behavior suggest that meloxicam was effective for reducing post-surgical pain and distress associated with calf dehorning...
  9. pmc Pangolin expression influences the development of a morphological novelty: beetle horns
    Bethany R Wasik
    Department of Biology, Indiana University, Bloomington, Indiana, USA
    Genesis 50:404-14. 2012
    ..pan), to investigate the role of Wnt signaling in the development of evolutionarily novel body structures: the horns of beetles...
  10. ncbi Live fast, die young: trade-offs between fitness components and sexually antagonistic selection on weaponry in Soay sheep
    Matthew R Robinson
    Institute of Evolutionary Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, United Kingdom
    Evolution 60:2168-81. 2006
    ..Soay sheep display a phenotypic polymorphism for horn type with males growing either normal or reduced (scurred) horns, and females growing either normal, scurred, or no (polled) horns; further variation in size exists within horn ..
  11. pmc Diversification of doublesex function underlies morph-, sex-, and species-specific development of beetle horns
    Teiya Kijimoto
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    Proc Natl Acad Sci U S A 109:20526-31. 2012
    ..In addition, horns lack obvious homology to other insect traits and provide a good opportunity to explore the molecular basis of the ..
  12. pmc The role of doublesex in the evolution of exaggerated horns in the Japanese rhinoceros beetle
    Yuta Ito
    Laboratory of Sericulture and Entomoresources, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464 8601, Japan
    EMBO Rep 14:561-7. 2013
    Male-specific exaggerated horns are an evolutionary novelty and have diverged rapidly via intrasexual selection...
  13. ncbi The intensity of sexual selection predicts weapon size in male bovids
    Jakob Bro-Jørgensen
    Department of Biological and Environmental Science, University of Jyvaskyla, Finland
    Evolution 61:1316-26. 2007
    As a classical example of a sexually selected trait, the horns of male bovids offer a prime opportunity to identify predictors of the intensity of sexual selection...
  14. ncbi Effects of local anesthetic and a nonsteroidal antiinflammatory drug on pain responses of dairy calves to hot-iron dehorning
    M Stewart
    AgResearch Ltd, Private Bag 3123, Hamilton 3240, New Zealand
    J Dairy Sci 92:1512-9. 2009
    ..In addition, this study demonstrated that the combination of LA and NSAID mitigated the onset of pain responses when the LA wanes...
  15. ncbi The impact of meloxicam on postsurgical stress associated with cautery dehorning
    A Heinrich
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    J Dairy Sci 92:540-7. 2009
    ..1 vs. control: 4 +/- 0.2) were greater in the control group compared with the meloxicam group. These results indicate that meloxicam reduced the physiological stress response to dehorning...
  16. pmc The scurs inheritance: new insights from the French Charolais breed
    Aurélien Capitan
    INRA, UMR 1313 Génétique Animale et Biologie Intégrative, F 78350 Jouy en Josas, France
    BMC Genet 10:33. 2009
    Polled animals are valued in cattle industry because the absence of horns has a significant economic impact...
  17. ncbi SNP-based association mapping of the polled gene in divergent cattle breeds
    D Seichter
    Tierzuchtforschung e V München, Senator Gerauer Strasse 23, 85586, Grub, Germany
    Anim Genet 43:595-8. 2012
    ..For the final identification of the causal mutation, we suggest high-throughput sequencing of the entire candidate region, because the identification of functional candidate genes is difficult owing to the lack of a comparable model...
  18. pmc Transcription profiling provides insights into gene pathways involved in horn and scurs development in cattle
    Maxy Mariasegaram
    CSIRO Livestock Industries, St Lucia, Queensland, Australia
    BMC Genomics 11:370. 2010
    Two types of horns are evident in cattle - fixed horns attached to the skull and a variation called scurs, which refers to small loosely attached horns. Cattle lacking horns are referred to as polled...
  19. pmc On the origin and evolutionary diversification of beetle horns
    Douglas J Emlen
    Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA
    Proc Natl Acad Sci U S A 104:8661-8. 2007
    Many scarab beetles produce rigid projections from the body called horns. The exaggerated sizes of these structures and the staggering diversity of their forms have impressed biologists for centuries...
  20. ncbi Rapid antagonistic coevolution between primary and secondary sexual characters in horned beetles
    Harald F Parzer
    Department of Biology, Indiana University, Bloomington, Indiana, USA
    Evolution 62:2423-8. 2008
    ..We discuss the implications of our results on the causes and consequences of resource allocation trade-offs in insects...
  21. ncbi A 2.5-Mb contig constructed from Angus, Longhorn and horned Hereford DNA spanning the polled interval on bovine chromosome 1
    K R Wunderlich
    Department of Animal Science, Texas A and M University, College Station, TX 77843, USA
    Anim Genet 37:592-4. 2006
    ..This contig of overlapping BAC clones from horned and polled breeds is a useful resource for SNP discovery and characterization of positional candidate genes...
  22. ncbi Integrating micro- and macroevolution of development through the study of horned beetles
    A P Moczek
    Department of Biology, Indiana University, 915 E Third Street, Myers Hall 150, Bloominton, IN 47405 7107, USA
    Heredity (Edinb) 97:168-78. 2006
    ..Here, I review the genetic, developmental, endocrine, and ecological basis of beetle horns, a morphological novelty that exhibits remarkable diversity both below and above the species level...
  23. pmc EST and microarray analysis of horn development in Onthophagus beetles
    Teiya Kijimoto
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    BMC Genomics 10:504. 2009
    ..Here we explore the genetic and genomic basis of a class of traits that is both novel and highly diverse, in a group of organisms that is ecologically complex and experimentally tractable: horned beetles...
  24. pmc An investigation into the practices of dairy producers and veterinarians in dehorning dairy calves in Ontario
    Laine J Misch
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Ontario, Canada
    Can Vet J 48:1249-54. 2007
    ..Thirteen percent of producers were unaware of the options for pain management. These results suggest that veterinarians should take the initiative to educate their clients about the options for pain management...
  25. pmc Function of weaponry in females: the use of horns in intrasexual competition for resources in female Soay sheep
    Matthew R Robinson
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
    Biol Lett 3:651-4. 2007
    ..for horn development, producing either full (normal horned), reduced (scurred) or no (polled, females only) horns. During the lambing period, females who possessed horns were more likely to initiate and win aggressive ..
  26. ncbi Species identification of rhinoceros horns using the cytochrome b gene
    Hsing Mei Hsieh
    Department of Forensic Science, Central Police University, 56 Shu Jen Road, Kwei San, Taoyuan 33334, Taiwan, ROC
    Forensic Sci Int 136:1-11. 2003
    ..present identification of the species is possible by DNA sequencing of the material, such as powdered rhinoceros horns. The unambiguous identification of rhino products using a 402 bp fragment of cytochrome b gene was investigated...
  27. ncbi Insulin signaling and limb-patterning: candidate pathways for the origin and evolutionary diversification of beetle 'horns'
    D J Emlen
    Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
    Heredity (Edinb) 97:179-91. 2006
    Beetle 'horns' are rigid outgrowths of the insect cuticle used as weapons in contests for access to mates. Relative to their body size, beetle horns can be enormous...
  28. pmc Evolutionary trade-off between weapons and testes
    Leigh W Simmons
    Centre for Evolutionary Biology, School of Animal Biology M092, University of Western Australia, Crawley, Western Australia 6009, Australia
    Proc Natl Acad Sci U S A 103:16346-51. 2006
    ..In a within-species study, we prevented males from developing horns and found that these males grew larger and invested relatively more in testes growth than did males allowed to ..
  29. ncbi New markers on bovine chromosome 1 are closely linked to the polled gene in Simmental and Pinzgauer cattle
    B Harlizius
    Department of Animal Breeding and Genetics, Hannover School of Veterinary Medicine, Bunteweg 17p, D 30559 Hannover, Germany
    Mamm Genome 8:255-7. 1997
    ..00 (Lod = 6.92), and theta = 0.033 (Lod = 6. 52) respectively. The microsatellite INRA117 (D1S20) and the gene for interferon-alpha receptor (IFNAR) show maximum Lod scores of 2.1 and 1.8 at a recombination rate of zero...
  30. ncbi Deep homology and the origins of evolutionary novelty
    Neil Shubin
    Department of Organismal Biology and Anatomy, University of Chicago, 1027 East 57th Street, Chicago, Illinois 60637, USA
    Nature 457:818-23. 2009
    ..some of the structures that most intrigued Charles Darwin, including animal eyes, tetrapod limbs and giant beetle horns. In each case, structures arose by the modification of pre-existing genetic regulatory circuits established in ..
  31. ncbi Diversity in the weapons of sexual selection: horn evolution in the beetle genus Onthophagus (Coleoptera: Scarabaeidae)
    Douglas J Emlen
    Division of Biological Sciences, The University of Montana, Missoula, Montana 59812, USA
    Evolution 59:1060-84. 2005
    ..Here, we characterize the evolutionary radiation of one type of weapon: beetle horns. We use partial sequences from four nuclear and three mitochondrial genes to develop a phylogenetic hypothesis for ..
  32. ncbi Effect of hot-iron disbudding on behaviour and plasma cortisol of calves sedated with xylazine
    G Stilwell
    Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinaria, UTL, Alto da Ajuda, Lisboa, Portugal
    Res Vet Sci 88:188-93. 2010
    ....
  33. pmc Evolution of ruminant headgear: a review
    Edward Byrd Davis
    Museum of Natural and Cultural History and Department of Geological Sciences, University of Oregon, Eugene, OR 97403 1224, USA
    Proc Biol Sci 278:2857-65. 2011
    The horns, ossicones and antlers of ruminants are familiar and diverse examples of cranial appendages...
  34. ncbi The scurs locus in cattle maps to bovine chromosome 19
    M Asai
    Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Anim Genet 35:34-9. 2004
    Polled, or the absence of horns, is a desirable trait for many cattle breeders. However, the presence of scurs, which are small horn-like structures that are not attached to the skull, can lower the value of an animal...
  35. ncbi Cortisol responses to dehorning of calves given a 5-h local anaesthetic regimen plus phenylbutazone, ketoprofen, or adrenocorticotropic hormone prior to dehorning
    M A Sutherland
    Animal Welfare Science and Bioethics Centre, College of Sciences, Massey University, Palmerston North, New Zealand
    Res Vet Sci 73:115-23. 2002
    ..Phenylbutazone did not affect the sensory input from the amputation wounds in the present calves...
  36. ncbi A comparison of catecholamine and cortisol responses of young lambs and calves to painful husbandry procedures
    D J Mellor
    Animal Welfare Science and Bioethics Centre, College of Sciences, Massey University, Palmerston North, New Zealand
    Aust Vet J 80:228-33. 2002
    ..To compare the changes in plasma concentrations of noradrenaline, adrenaline and cortisol in lambs after ring castration plus tailing and in calves after dehorning with or without prior local anaesthesia...
  37. ncbi Pharmacokinetics and physiologic effects of intramuscularly administered xylazine hydrochloride-ketamine hydrochloride-butorphanol tartrate alone or in combination with orally administered sodium salicylate on biomarkers of pain in Holstein calves followi
    Sarah L Baldridge
    Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA
    Am J Vet Res 72:1305-17. 2011
    ....
  38. ncbi Gigantic cutaneous horns of the scalp: lesions with a gross similarity to the horns of animals: a report of four cases
    Michal Michal
    Department of Pathology, Laborator Spec Diagnostiky Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Surg Pathol 26:789-94. 2002
    Gigantic cutaneous horns, grossly similar to the horns seen in animals, are exceedingly rare in humans...
  39. ncbi Possible spread of bovine viral diarrhoea virus by contaminated medicine
    J Katholm
    Department of Large Animal Sciences, Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    Vet Rec 158:798-9. 2006
  40. ncbi Severe haematoma of the vulva and defloration caused by goring
    M Ihsan Okur
    Department of Plastic and Reconstructive Surgery, Firat Medical Center, Firat University, 23119 Elazig, Turkey
    Eur J Obstet Gynecol Reprod Biol 119:250-2. 2005
    ..We present a case of haematoma of the vulva caused by goring by a cow. The hymen and vaginal wall were also lacerated. Evacuation of the haematoma and repair of lacerated tissues were successfully performed...
  41. ncbi Activity levels of 137Cs and 40K in the skin and the cutaneous organs of a cow
    Elke Pichl
    Reaktorinstitut und Institut für Technische Physik, Technische Universitat Graz, Steyrergasse 17, A 8010 Graz, Austria
    Health Phys 85:159-64. 2003
    ..The current investigation measured concentrations of 137Cs and 40K in components of the skin, horns, and hooves of a cow...
  42. ncbi Routine surgical procedures in dairy cattle under field conditions: abomasal surgery, dehorning, and tail docking
    Pascale Aubry
    Department of Clinical Sciences, Faculte de Medecine Veterinaire, Universite de Montreal, C P 5000, Saint Hyacinthe, Quebec J2S 7C6, Canada
    Vet Clin North Am Food Anim Pract 21:55-72. 2005
    ..This article also addresses the need for anesthesia when dehorning and tail docking dairy cattle. The justifications for routine use of these two procedures are discussed, mainly from an animal welfare standpoint...
  43. ncbi Dehorning and disbudding distress and its alleviation in calves
    K J Stafford
    Animal Welfare Science and Bioethics Centre, Institute of Veterinary Animal and Biomedical Sciences, College of Sciences, Massey University, Palmerston North, New Zealand
    Vet J 169:337-49. 2005
    ..Cautery disbudding is preferable to amputation dehorning, but for optimal pain relief xylazine sedation, local anaesthesia and a NSAID should be used with both procedures...
  44. ncbi Behavioural responses of calves to amputation dehorning with and without local anaesthesia
    S P Sylvester
    Animal Welfare Science and Bioethics Centre, College of Sciences, Massey University, Palmerston North, New Zealand
    Aust Vet J 82:697-700. 2004
    ..To assess the pain elicited by amputation dehorning and evaluate the effect of local anaesthesia by using changes in calf behaviour...
  45. ncbi Dielectric properties of a protein-water system in selected animal tissues
    E Marzec
    Department of Biophysics, Poznan University of Medical Sciences, Fredry 10, 61 701 Poznan, Poland
    Bioelectrochemistry 65:89-94. 2005
    ....
  46. pmc The utility of ketoprofen for alleviating pain following dehorning in young dairy calves
    Barry N Milligan
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1
    Can Vet J 45:140-3. 2004
    ..05) in the ketoprofen-treated group. These results suggest that ketoprofen, in addition to local anesthesia, may alleviate short-term pain following dehorning with a butane dehorning device in dairy calves less than 2 weeks of age...
  47. ncbi The hardness of horn in different segments of the bovine claw
    Christine Hinterhofer
    Klinik für Orthopädie bei Huf und Klauentieren, Dept V der Veterinärmedizinischen Universität Wien, Austria
    Berl Munch Tierarztl Wochenschr 118:334-40. 2005
    ..Measurements of the claw capsule showed thickness of the hoof wall increasing from the coronary border towards the sole. In dorsopalmar/-plantar direction, bovine hoof wall at the weight bearing border decreases towards the heel...
  48. pmc Trilobite spines and beetle horns: sexual selection in the Palaeozoic?
    Robert J Knell
    School of Biological Sciences, Queen Mary, University of London, London, UK
    Biol Lett 1:196-9. 2005
    ..This interpretation is supported by four lines of evidence: their ontogeny, their diversity, the existence of plausible examples of sexual dimorphs in some cases and the fact that they show positive allometry...
  49. ncbi Environmental heterogeneity generates fluctuating selection on a secondary sexual trait
    Matthew R Robinson
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh, United Kingdom
    Curr Biol 18:751-7. 2008
    ..Such fluctuating selection may play an important role in preventing the erosion of genetic variance in secondary sexual traits...
  50. ncbi Epidemiological aspects of bovine parasitic otitis caused by Rhabditis spp. and/or Raillietia spp. in the state of Minas Gerais, Brazil
    E R Duarte
    Department of Microbiology, Federal University of Minas, Biological Science Institute, ICB/UFMG, , 6627, 31270-901, Belo Horizonte, Minas Gerais, Brazil
    Vet Parasitol 101:45-52. 2001
    ..in the dry and rainy seasons of Minas Gerais and correlating it with variables age, breed and the presence of horns. The secretion or cerumen of 981 cattle was collected with sterile swabs, placed in test tubes and exposed to ..
  51. ncbi Traumatic rupture of the globe caused by cow horns
    H Helbig
    Department of Ophthalmology, Kantonsspital St Gallen, Switzerland
    Eur J Ophthalmol 12:304-8. 2002
    We investigated the epidemiology, clinical findings and functional outcome of open-globe injuries caused by cow horns over a 50-year period in eastern Switzerland.
  52. ncbi Validation of the acute electroencephalographic responses of calves to noxious stimulus with scoop dehorning
    T J Gibson
    Animal Welfare Science and Bioethics Centre, Massey University, Private Bag 11222, Palmerston North, New Zealand
    N Z Vet J 55:152-7. 2007
    ..To validate use of the electroencephalogram (EEG) and a minimal anaesthesia model for assessment of noxious sensory input caused by scoop dehorning of calves...
  53. ncbi Urethrorectal fistula by bull horn injury
    D K Pal
    Division of Urology, Institute of Medical Sciences, Banaras Hindu University, Varanasi
    J Indian Med Assoc 100:47. 2002
    ..Initially sigmoid colostomy and suprapubic cystostomy was done. Later optical internal urethrotomy was done. The patient was catheterised for 3 weeks and the fistula healed completely...
  54. ncbi Glaucoma and subconjunctival crystalline lens following cow horn trauma: a rare case
    Selcuk Erdogan
    Can J Ophthalmol 42:762-3. 2007
  55. pmc Genetic and morphological characterisation of the Ankole Longhorn cattle in the African Great Lakes region
    Deo B Ndumu
    Department of Sustainable Agricultural Systems, BOKU University of Natural Resources and Applied Life Sciences, Vienna, Austria
    Genet Sel Evol 40:467-90. 2008
    ..Both analyses on distance-based and model-based methods consistently isolated the Mugamba sub-population in Burundi from the others...
  56. ncbi Facial injuries caused by animals in northern Nigeria
    V I Ugboko
    Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
    Br J Oral Maxillofac Surg 40:433-7. 2002
    ..Three dog bites were seen. Knocks from cows' horns (n=9) were the predominant mechanism of injury, followed by falls (n=8) and kicks (n=7)...
  57. ncbi Effect of local anaesthetic combined with wound cauterisation on the cortisol response to dehorning in calves
    M A Sutherland
    Animal Welfare Science and Bioethics Centre, College of Sciences, Massey University, Palmerston North, New Zealand
    Aust Vet J 80:165-7. 2002
    ..To reassess whether local anaesthesia before dehorning and wound cauterisation after dehorning eliminates the cortisol response to dehorning...
  58. ncbi Penetrating orbito-cranial and ocular cow-horn injuries
    L O Onyekwe
    Guinness Eye Center, Nnamdi Azikiwe University Teaching Hospital, Onitsha
    Niger J Clin Pract 10:177-9. 2007
    ..This uncommon cause of unilateral visual loss can be prevented if slaughtering of cows are done by trained and appropriately equipped personnel...
  59. ncbi Temperature-dependent dielectric properties of slightly hydrated horn keratin
    Tasneem Zahra Rizvi
    Department of Physics, Quaid i Azam University, Islamabad, Pakistan
    Int J Biol Macromol 42:292-7. 2008
    ..An overall rise in the permittivity was observed above 175 degrees C, which has been identified as the onset of chain melting in the crystalline region of the protein...
  60. ncbi Stress responses in adult cattle due to surgical dehorning using three different types of anaesthesia
    Renata Lepková
    Faculty of Veterinary Hygiene and Ecology VFU Brno, Czech Republic
    Berl Munch Tierarztl Wochenschr 120:465-9. 2007
    ..Local anaesthesia with lidocaine alone was least suitable...
  61. ncbi Horn growth related to testosterone secretion in two wild Mediterranean ruminant species: the Spanish ibex (Capra pyrenaica hispanica) and European mouflon (Ovis orientalis musimon)
    A Toledano-Diaz
    Dpto Reproducción Animal, SGIT INIA, Avda Puerta de Hierro Km 5 9, 28040 Madrid, Spain
    Anim Reprod Sci 102:300-7. 2007
    ..05). These results appear to support the hypothesis that high peripheral plasma levels of testosterone are linked with the seasonal arrest of horn growth during the rutting period...
  62. ncbi Rostral horn evolution among agamid lizards of the genus Ceratophora endemic to Sri Lanka
    James A Schulte
    Department of Biology, Washington University, St Louis, Missouri 63130, USA
    Mol Phylogenet Evol 22:111-7. 2002
    ..Phylogenetic analysis reveals multiple origins and possibly losses of rostral horns in the evolutionary history of Ceratophora...
  63. ncbi Age-dependent genetic effects on a secondary sexual trait in male Alpine ibex, Capra ibex
    Achaz Von Hardenberg
    Departement de Biologie, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Mol Ecol 16:1969-80. 2007
    Secondary sexual traits, such as horns in ungulates, may be good indicators of genetic quality because they are costly to develop...
  64. ncbi Evolutionary history of the genus Capra (Mammalia, Artiodactyla): discordance between mitochondrial DNA and Y-chromosome phylogenies
    Nathalie Pidancier
    Laboratoire d Ecologie Alpine, Génomique des Populations et Biodiversité, CNRS UMR 5553, Universite Joseph Fourier, B P 53, F 38041 Grenoble Cedex 9, France
    Mol Phylogenet Evol 40:739-49. 2006
    ..We suggest that a plausible scenario involves mtDNA introgression between ancestral taxa before the relatively recent colonization of Western Europe, the Caucasus Mountains, and East Africa by Capra populations...
  65. ncbi Cerebral infarction and meningoencephalitis following hot-iron disbudding of goat kids
    K G Thompson
    Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand
    N Z Vet J 53:368-70. 2005
    ..Twelve of 150 goat kids, 4-10 days old, died 3 days after disbudding with a hot iron. Another 18 kids had been ill the previous day but survived following antibiotic therapy. Five of the dead kids were necropsied...
  66. pmc Overt and covert competition in a promiscuous mammal: the importance of weaponry and testes size to male reproductive success
    B T Preston
    Institute of Biological Sciences, University of Stirling, Stirling FK9 4LA, UK
    Proc Biol Sci 270:633-40. 2003
    ..For males with large horns at least, this behavioural success translates into greater siring success...
  67. ncbi Monitoring the arsenic and iodine exposure of seaweed-eating North Ronaldsay sheep from the gestational and suckling periods to adulthood by using horns as a dietary archive
    Guilhem Caumette
    Department of Chemistry, College of Physical Sciences, University of Aberdeen, Meston Walk, Old Aberdeen AB24 3UE, Scotland, UK
    Environ Sci Technol 41:2673-9. 2007
    Trace elements often accumulate in keratin-rich tissues. Hair, nails, and horns grow steadily but once formed are metabolically inactive and provide an archive of trace element exposure when analyzed in segments...
  68. ncbi Undesirable evolutionary consequences of trophy hunting
    David W Coltman
    Department of Animal and Plant Sciences, University of Sheffield, Sheffield S10 2TN, UK
    Nature 426:655-8. 2003
    ..pedigree from a 30-year study of a wild population in which trophy hunting targeted rams with rapidly growing horns, to explore the evolutionary response to hunter selection on ram weight and horn size...
  69. ncbi Enhancement of citric acid production with ram horn hydrolysate by Aspergillus niger
    Esabi Basaran Kurbanoglu
    Department of Biology, Science and Letters Faculty, Ataturk University, 25240 Erzurum, Turkey
    Bioresour Technol 92:97-101. 2004
    ..For this purpose, first RHH was produced. Ram horns were hydrolyzed by treating with acid (6 N-H2SO4) and the RHH was obtained...
  70. ncbi Sheep horns downsized by hunters' taste for trophies
    John Whitfield
    Nature 426:595. 2003
  71. ncbi Horn growth rate and longevity: implications for natural and artificial selection in thinhorn sheep (Ovis dalli)
    J Loehr
    Department of Biological and Environmental Science, University of Jyvaskyla, Jyvaskyla, Finland
    J Evol Biol 20:818-28. 2007
    ..Large horn size can be achieved both by individuals that grow horns rapidly and by those that have greater longevity, and the trade-off between growth rate and longevity could limit ..
  72. pmc Quantitative genetics and sex-specific selection on sexually dimorphic traits in bighorn sheep
    Jocelyn Poissant
    Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada T6G 2E9
    Proc Biol Sci 275:623-8. 2008
    ..The absence of detectable sexually antagonistic selection suggests that currently there are no sexual conflicts at loci influencing horn volume and body mass...
  73. ncbi Has the kouprey (Bos sauveli Urbain, 1937) been domesticated in Cambodia?
    Alexandre Hassanin
    Origine, Structure et Evolution de la Biodiversité, UMR 5202, Departement Systematique et Evolution, Museum national d histoire naturelle, Paris, France
    C R Biol 329:124-35. 2006
    ..described in the literature reveal important differences concerning the body size, general coloration and horns. As these differences involve phenotypic traits that are strongly selected in case of domestication, we suggest ..
  74. ncbi Urogenital system of the spotted hyena (Crocuta crocuta Erxleben): a functional histological study
    Gerald R Cunha
    Department of Anatomy, University of California, San Francisco, California 94143, USA
    J Morphol 256:205-18. 2003
    ..urogenital tract of the female spotted hyena is typical of other carnivores and consists of the oviducts, uterine horns, uterine body, and vagina...
  75. ncbi [Usefulness of electromyography in diagnostics of the neuro-muscular diseases]
    Sławomir Kroczka
    Katedry Neurologii Dzieci i Młodziezy, Uniwersytet Jagielloński Collegium Medicum, Krakow
    Przegl Lek 66:913-9. 2009
    ..Electrophysiological examinations still play an important role in initial diagnostics of neuromuscular disorders and monitoring of the disease progress or recovery process...
  76. ncbi The neuropeptide tyrosine Y1R is expressed in interneurons and projection neurons in the dorsal horn and area X of the rat spinal cord
    P Brumovsky
    Department of Neuroscience, Karolinska Institutet, Retzius vag 8, B2 5, S 171 77 Stockholm, Sweden
    Neuroscience 138:1361-76. 2006
    ..area X); and Type 7) a small number of large Y1 receptor-positive neurons in the medial aspect of the ventral horns (lamina VIII)...
  77. ncbi Modus operandi of oviposition in Dermacentor reticulatus (Acari: Ixodidae)
    J Sieberz
    Institute for Comparative Tropical Medicine and Parasitology, Munich, Germany
    Exp Appl Acarol 24:63-76. 2000
    ..the vestibulum vaginae prolapsed, forming the ovipositor as an extended tube which handed over an egg to the two horns of the cuticular sac after a brief, but intensive, contact with the cuticular sac...
  78. ncbi [Descent of ova and embryos in cows superovulated with serum gonadotropin]
    L Holy
    Vysoká skola veterinární, Brno
    Vet Med (Praha) 37:353-64. 1992
    ..1) were divided into five segments (two on oviducts and three on uterine horns) by the applied ligature...
  79. ncbi [The hyoid bone and vertical dimension]
    A Doual
    Faculté d Odontologie, Lille
    Orthod Fr 74:333-63. 2003
    ..True articulations between the body and the horns of the hyoid bone persist for a very long time; and so the junction between the small horns doesn't fully calcify ..
  80. ncbi [Hemorheology and microcirculation in some pathologies of internal medicine]
    G Cicco
    CEMOT, Centro Interdipartimentale di Ricerca in Emoreologia, Microcircolazione, Trasporto di Ossigeno e Tecnologie Ottiche non Invasive, Universita degli Studi di Bari, Bari
    Minerva Med 98:625-31. 2007
    ..It is very interesting in physiopathology to evaluate the blood flow in the microvasculature of patients affected by diabetes, arterial hypertension, lipoproteinosis, peripheral occlusive arterial disease (POAD) and liver failure...
  81. pmc Spinal muscular atrophy genetic counseling access and genetic knowledge: parents' perspectives
    Candice Meldrum
    University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    J Child Neurol 22:1019-26. 2007
    Spinal muscular atrophy is characterized by degeneration of alpha motor neurons in the anterior horns of the spinal cord, which leads to progressive symmetrical muscle weakness and atrophy...
  82. ncbi Intercellular communication in in vivo- and in vitro-produced bovine embryos
    R Boni
    Dipartimento di Scienze delle Produzioni Animali, 85100 Potenza, Italy
    Biol Reprod 61:1050-5. 1999
    In vivo bovine embryos were obtained by nonsurgical flushing of uterine horns of cows submitted to superovulatory treatment, while in vitro embryos were generated from oocytes collected from slaughtered donors...
  83. ncbi Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene
    Shoichi Sasaki
    Department of Neurology, Neurological Institute, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku ku, 162 8666, Tokyo, Japan
    Acta Neuropathol 107:461-74. 2004
    ..Non-transgenic littermates occasionally exhibited vacuolar changes in the axons of anterior horns. However, they were smaller both in size and number than those in transgenic mice...
  84. ncbi Cytochemical and molecular characteristics of the process of cornification during feather morphogenesis
    Lorenzo Alibardi
    Dipartimento di Biologia Evoluzionistica Sperimentale, Via Selmi 3, University of Bologna, 40126 Bologna, Italy
    Prog Histochem Cytochem 43:1-69. 2008
    ..keratins of intermediate filaments, and functionally correspond to keratin-associated proteins of hairs, nails and horns in mammals...
  85. ncbi Clinical considerations of microleakage
    D H Pashley
    Department of Oral Biology Physiology, School of Dentistry, Medical College of Georgia, Augusta
    J Endod 16:70-7. 1990
    ..Thicker dentin is less permeable than thin dentin. Dentin over pulp horns is more permeable than central dentin...
  86. ncbi Ultrastructural pathology of a Chilean case of tropical spastic paraparesis/human T-cell lymphotropic type I-associated myelopathy (TSP/HAM)
    P P Liberski
    Laboratory of Central Nervous System Studies, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Ultrastruct Pathol 23:157-62. 1999
    ..The pathology of the anterior and posterior horns was similar and was comprised of axonal degeneration, accompanied by extensive astrocytic gliosis...
  87. ncbi [Hyperprolactinemia effects on the female mice uterus during proestrous]
    Regina Célia Teixeira Gomes
    Departamento de Ginecologia, Universidade Federal de São Paulo UNIFESP São Paulo, SP, Brasil
    Rev Bras Ginecol Obstet 31:385-90. 2009
    ..To evaluate the effect of hyperprolactinemia induced by metoclopramide on the endometrium and myometrium of female mice in the proestrus phase...
  88. ncbi A field study into the appropriateness of transcutaneous ultrasonography in the diagnoses of uterine disorders in reproductively failed pigs
    Johannes Kauffold
    Large Animal Clinic for Theriogenology and Ambulatory Services, Faculty of Veterinary Medicine, University of Leipzig, An den Tierkliniken 29, 04103 Leipzig, Germany
    Theriogenology 64:1546-58. 2005
    ..uterine size (US; expressed as the mean sectional area of two to three cross-sections of the uterine horns given in cm2) and intrauterine content...
  89. ncbi Adhesion prevention with ancrod released via a tissue-adherent hydrogel
    S M Chowdhury
    Department of Chemical Engineering, University of Texas, Austin 78712, USA
    J Surg Res 61:58-64. 1996
    ..The experimental model involved ischemic and serosal injury to the uterine horns of rats with measurement of adhesions 7 days after injury...
  90. pmc Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia
    Hermann H Bragulla
    Department of Comparative Biomedical Sciences, Louisiana State University, Baton Rouge, 70803, USA
    J Anat 214:516-59. 2009
    Historically, the term 'keratin' stood for all of the proteins extracted from skin modifications, such as horns, claws and hooves...
  91. ncbi [Profile of sulphated glycosaminoglycans content in the murine uterus during the different phases of the estrous cycle]
    Regina Célia Teixeira Gomes
    Departamentos de Bioquímica, Morfologia e Ginecologia da Universidade Federal de São Paulo, Rua Borges Lagoa 783, Vila Clementino, Sao Paulo, CEP 04038 031, SP, Brazil
    Rev Assoc Med Bras 53:261-6. 2007
    ..Identification and quantitation of sulphated glycosaminoglycans (GAGs) in the uterus of female mice during the estrous cycle...
  92. ncbi Slow component of axonal transport is impaired in the proximal axon of transgenic mice with a G93A mutant SOD1 gene
    Shoichi Sasaki
    Department of Neurology, Neurological Institute, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku ku, 162 8666 Tokyo, Japan
    Acta Neuropathol 107:452-60. 2004
    ..were more prominent in the proximal axons, including swollen axons (spheroids) and neuropils of the anterior horns. Vacuoles in the axons were frequently large enough to occupy almost the entire axonal caliber...
  93. ncbi Number of spermatozoa in the crypts of the sperm reservoir at about 24 h after a low-dose intrauterine and deep intrauterine insemination in sows
    P Tummaruk
    Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand
    Reprod Domest Anim 45:208-13. 2010
    ..The oviducts and the proximal part of the uterine horns (1 cm) on each side of the reproductive tracts were collected. The section was divided into four parts, i.e...
  94. ncbi Embryo production from superovulated Holstein-Friesian dairy heifers and cows after insemination with frozen-thawed sex-sorted X spermatozoa or unsorted semen
    J Peippo
    MTT Agrifood Research Finland, Biotechnology and Food Research, Building H, FI 31600 Jokioinen, Finland
    Anim Reprod Sci 111:80-92. 2009
    ..Low-dose X-sorted inseminates were deposited into uterine horns and unsorted semen was placed into the uterine body. In Experiment 1, on average 70.3 and 75...
  95. ncbi 98 the fetal and postnatal effects of periconceptional hyperglycemia using a rabbit model
    R Brat
    Institut National de la Recherhche Agronomique, Jouy en Josas, France
    Reprod Fertil Dev 23:154. 2011
    ..In Expt. 1, embryos from D (n=11) and C (n=13) groups were transferred respectively to the right and left horns of 3 female recipients, which were killed on Day 28. In Expt. 2, 17 D and 16 C females were mated naturally...
  96. ncbi Influence of post-ovulatory insemination on sperm distribution, pregnancy and the infiltration by cells of the immune system, and the distribution of CD2, CD4, CD8 and MHC class II expressing cells in the sow endometrium
    K Kaeoket
    Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    J Vet Med A Physiol Pathol Clin Med 50:169-78. 2003
    ..The uterine horns were flushed to control for the presence of spermatozoa and neutrophils and/or for recovery of oocytes and/or ..
  97. ncbi Distribution of spermatozoa and embryos in the female reproductive tract after unilateral deep intra uterine insemination in the pig
    P Tummaruk
    Department of Obstetrics Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok, Thailand
    Reprod Domest Anim 42:603-9. 2007
    ..The oviducts and the uterine horns on each side of the reproductive tracts were divided into seven segments, namely ampulla, cranial isthmus, caudal ..
  98. ncbi Frequency of sub-clinical cerebral edema in children with diabetic ketoacidosis
    Nicole S Glaser
    Department of Pediatrics, University of California Davis School of Medicine, Sacramento 95817, USA
    Pediatr Diabetes 7:75-80. 2006
    ..In this study, we measured the intercaudate width of the frontal horns of the lateral ventricles using magnetic resonance imaging (MRI) in children with DKA during treatment and after ..
  99. ncbi The distribution of parenchyma, follicles, and lymphocyte subsets in thymus of patients with myasthenia gravis, with special reference to remission after thymectomy
    Takeshi Mori
    Department of Thoracic Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    J Thorac Cardiovasc Surg 133:364-8. 2007
    ..We sought to examine the distribution of parenchyma, follicles, and lymphocyte subsets in the thymus of patients with myasthenia gravis and to identify determinants of remission after thymectomy...
  100. ncbi Spatiotemporal CCR1, CCL3(MIP-1α), CXCR4, CXCL12(SDF-1α) expression patterns in a rat spinal cord injury model of posttraumatic neuropathic pain
    Friederike Knerlich-Lukoschus
    Department of Neurosurgery, University of Schleswig Holstein Medical Center, Kiel, Germany
    J Neurosurg Spine 14:583-97. 2011
    ....

Research Grants62

  1. Innate Immune Mechanisms of Motor Neuron Injury
    Timothy Vartanian; Fiscal Year: 2010
    ..Administration of a TLR3 agonist in neonatal mice results in a loss of islet-1 positive neurons within the ventral horns. A clue into the cause of selective motor neuron death may be the observation that TLR3 recruits either cell-death ..
  2. Role of Stasimon Dysfunction in Spinal Muscular Atrophy
    Livio Pellizzoni; Fiscal Year: 2013
    ..These will include motor neurons (MNs) in the ventral horns of the lumbar spinal cord and proprioceptive neurons located in the dorsal root ganglia (DRG)...
  3. Mechanisms of Central Synaptic Dysfunction in SMA
    GEORGE ZACHARIAS MENTIS; Fiscal Year: 2013
    ..These will include motor neurons in the ventral horns of the lumbar spinal cord and several other neuronal and non-neuronal populations...
  4. Central mechanisms of maintenance of orofacial pain after injury
    Asaf Keller; Fiscal Year: 2013
    ..hypersensitivity due to sensitization of peripheral nociceptors and neurons in the medullary and spinal dorsal horns as well as other sites in the central nervous system (CNS)...
  5. White Matter Lesions and Cortical Serotonergic Deafferentation in Older Adults
    Martijn L T M Muller; Fiscal Year: 2010
    ..have an anatomic predilection for the periventricular white matter areas, including the periventricular frontal horns, which are also an area of increased density of passing serotoninergic projection fibers, we propose to test the ..
  6. Modularity of gene expression and tradeoffs in the evolution of plasticity
    EMILIE SNELL ROOD; Fiscal Year: 2010
    ..This research tests several predictions by contrasting the development of secondary sexual traits (horns) and brains in horned (aggressive fighter) and hornless (non-aggressive sneaker) beetle morphs...
  7. The mechanisms of action of T-lymphocytes in neuropathic pain
    Michael Costigan; Fiscal Year: 2013
    ..hypersensitivity and we have used this phenomenon to perform a whole genome expression screen of the spinal dorsal horns ipsilateral to the injured sciatic nerve from neonates (with no hypersensitivity) and adults (with chronic pain-..
  8. EXCITOTOXIN EFFECTS ON SPINAL CORD IN VITRO
    JOHN DELFS; Fiscal Year: 1992
    ..Our studies show damage to ventral and dorsal horns in OTC-SCs by the excitotoxin, N-methyl-D-aspartic acid (NMDA)...
  9. Arginase and Regulation of Nitric Oxide Synthase in ALS
    Rajiv Ratan; Fiscal Year: 2004
    ..The principal pathological finding in amyotrophic lateral sclerosis is loss of nerve cells in the anterior horns of the spinal cord, the motor nuclei of the brainstem, and the upper motor neurons of the cerebral cortex...
  10. Smoke Detector Alert for the Deaf
    RICHARD ROBY; Fiscal Year: 2004
    ..identification algorithm developed in Phase I research to include nonperiodic smoke detectors and emergency alarm horns. The second path of this research involves testing deaf, hearing-impaired and hearing able individuals for their ..
  11. CHOLINERGIC MECHANISMS IN AGING AND AD
    LINCOLN POTTER; Fiscal Year: 2002
    ..1c) Autoradiography will be used to localize 125I-m4-toxin in the dorsal horns of the human and rat spinal cord, and dorsal root rhizotomy in the rat will indicate whether m4 receptors are on ..
  12. AUTONOMIC NERVOUS CONTROL OF ORGANS
    Masahito Kawatani; Fiscal Year: 1990
    ..of the neural pathways to different parts of the reproductive system (clitoris, uterine cervix, uterine horns)...
  13. BRAIN MORPHOLGY IN OBSESSIVE-COMPULSIVE DISORDER
    Delbert Robinson; Fiscal Year: 1993
    ..cingulate gyrus and amygdala-hippocampus complex); 4) the lateral ventricle with its subdivisions, the frontal horns, central parts, occipital horns and temporal horns (an indirect measure of change in volume of the hemispheres, ..
  14. CELL NON-AUTONOMOUS MODE OF TUMOR SUPPRESSION BY BRCA1
    Louis Dubeau; Fiscal Year: 2009
    ..40/59) of Brca1 knockout mice had grossly visible cystic tumors either attached to the ovary, to the uterine horns, or with no demonstrable attachment to either of these organs...
  15. Aquaporins and Neuropathic Pain after Spinal Cord Injury
    Olivera Nesic Taylor; Fiscal Year: 2009
    ..It has been shown that AQP1 is important for normal pain processing in mouse dorsal horns. We hypothesize that small interfering RNA specific for rat AQP4 (AQP4 siRNA) will block persistent up-regulation ..
  16. Uterine circulatory response to exercise in pregnancy
    KATHLEEN O HAGAN; Fiscal Year: 2004
    ..instrumented with flowprobes on the right and left uterine arteries to measure blood flow to the uterine horns, and one oviduct is ligated, to prevent pregnancy in that horn...
  17. MORPHOLOGY & SOMATOTOPY IN THE DORSAL HORN
    Paul Brown; Fiscal Year: 1992
    ..inject primary afferent axons in the white matter with HRP, followed by detailed mapping of the dorsal and ventral horns and Intermediate grey matter...
  18. Endometrial Mosaic Creation Via Visual Motion Tracking
    ANANTH NATARAJAN; Fiscal Year: 2004
    ..Third, imaging of the uterine horns will become possible as lateral movement of the scope is interpreted by the software...
  19. ANN SOFTWARE FOR EARLY DETECTION OF OVARIAN CANCER
    Hong Zhang; Fiscal Year: 2000
    ..b>Horns presently offers as a commercial product an Internet-based clinical information processing service, called ..
  20. Female Reproductive Organs and Their Innervation.
    RAYMOND PAPKA; Fiscal Year: 2006
    ..Finally, knowledge of estrogen responsive sensory neurons has important implications for understanding neuropathic pain syndromes influenced by estrogen levels. ..
  21. ANATOMICAL STUDIES OF BRAINSTEM CARDIOVASCULAR SYSTEMS
    Sue Aicher; Fiscal Year: 2007
    ..This collaborative project provides a unique opportunity to directly address structural and physiological questions regarding NTS neuronal function in both the normal and hypertensive states. [unreadable] [unreadable]..
  22. A New Approach to Sound Source Identification
    Robert Lutfi; Fiscal Year: 2009
    ..abstract_text> ..
  23. Pain Mechanisms and the Development of Analgesics
    Tony Yaksh; Fiscal Year: 2006
    ..g. COX2 inhibitors, GABApentin, ziconotide) and failures (NK1 antagonist). [unreadable] [unreadable] [unreadable]..
  24. PDE3 Inhibitors: Selective Blockers of Oocyte Maturation
    Jeffrey Jensen; Fiscal Year: 2007
    ..This approach is expected to provide a foundation for future Phase 1 trials of PDE3 inhibitors in humans. ..
  25. Insulin and Oocyte Chromatin Segregation
    Gary Smith; Fiscal Year: 2009
    ..abstract_text> ..
  26. Microglial Regulation in Opioid Tolerance, Hyperalgesia and Addiction
    JOYCE DELEO; Fiscal Year: 2009
    ..These studies may also aid in elucidating substance abuse-induced plasticity, the physiological correlate to craving and relapse in drug addiction. ..
  27. Computational Modeling of High-Field MR Images
    Paul M Thompson; Fiscal Year: 2010
    ..We will share all images, protocols, and algorithms with our network of 100+ collaborating laboratories. ..
  28. A Multidimensional Alzheimer's Disease Brain Atlas
    Paul M Thompson; Fiscal Year: 2010
    ..We will share all images, protocols, and algorithms with our 100+ collaborating laboratories. ..
  29. LOCALIZATION OF MRNAS AT SYNAPTIC SITES ON DENDRITES
    Oswald Steward; Fiscal Year: 2011
    ..These studies will provide novel insights into the basic mechanisms underlying information storage in the brain and neurological disorders that disrupt this fundamental mechanism, including Fragile-X Mental Retardation Syndrome. ..
  30. Mechanisms of virus-induced apoptosis in neurons and CNS
    Kenneth L Tyler; Fiscal Year: 2010
    ..pathways involved, as well as an easily accessible in mouse model of CNS apoptosis that allows rapid testing of results obtained in cell culture for their significance on the pathogenesis of CNS viral disease in vivo ..
  31. Cytokine and MAP Kinase Involvement in Neuropathic Pain
    Linda Sorkin; Fiscal Year: 2008
    ..This approach has the potential for avoiding some of the problems that occur with complete inhibition of p38 function. ..
  32. Brain Recovery Following Abstinence From Cocaine
    Jay Nierenberg; Fiscal Year: 2002
    ..These data will help assess the feasibility of a longitudinal study of WM changes related to CD and potentially inform future treatment options. ..
  33. Ca permeable non-NMDAr: New spinal sensitization pathway
    Linda Sorkin; Fiscal Year: 2005
    ..We propose to investigate the effects of Ca-permeable non-NMDAr activation on ERK and CREB phosphorylation (using Western blots and immunohistochemistry), expression of c-fos and development of hyperalgesia. ..
  34. PROTEIN PHOSPHATASES AND OOCYTE MEIOSIS
    Gary Smith; Fiscal Year: 2002
    ..These studies will provide novel information concerning control of oocyte maturation and spindle formation that may subsequently influence the developmental competency of resulting embryos. ..
  35. MARIJUANA WITHDRAWAL
    J Walker; Fiscal Year: 2002
    ..In addition, the investigations in the hippocampus may have relevance to learning and memory and thus have implications for certain mental illnesses such as Alzheimer's disease or other diseases that affect mental health. ..
  36. Parkinsonian mouse model: impaired respiratory enzymes
    Lars Olson; Fiscal Year: 2005
    ..2. To determine if respiratory chain dysfunction in DA neurons will induce a PD like phenotype and validate this approach as a new and unique model of Parkinson's Disease. ..
  37. NEUROBIOLOGY OF PAIN
    Tony Yaksh; Fiscal Year: 2005
    ..The complexity of the problems and the diversity of the training approaches emphasize that the training received by these fellows will provide a broad base of knowledge relevant to wide areas of neurobiology. ..
  38. Novel PDEs for Cortical Mapping and Analysis in Disease
    Paul Thompson; Fiscal Year: 2004
    ..abstract_text> ..
  39. Perception of Sources of Environmental Sounds
    Valeriy Shafiro; Fiscal Year: 2003
    ..The findings of the study will be relevant to cochlear implant design, and will provide an empirical basis for a theory of environmental sound perception. ..
  40. SMOOTH MUSCLE-EPITHELIAL INTERACTIONS IN PROSTATE CANCER
    Gerald Cunha; Fiscal Year: 2001
    ..In addition, it is possible that this study will identify one or more strategies for regulating the growth, differentiation and)'or invasive behavior of prostatic carcinoma cells. ..
  41. Mechanisms of apoptosis in the central nervous system
    Kenneth Tyler; Fiscal Year: 2009
    ..In addition, the proposed studies will evaluate the role of these genes and pathways as novel therapeutic targets for these diseases. ..
  42. NEUROLOGICAL BASIS OF PAIN: ROLE OF CANNABINOIDS
    J Walker; Fiscal Year: 2003
    ..The results of these studies will reveal mechanisms by which cannabinoids modulate the pathological pain, and suggests future studies directed at determining the role of endocannabinoids in pain processing. ..
  43. Characterization of Toxicity with Spinal Opiates
    Tony L Yaksh; Fiscal Year: 2010
    ..The present studies aim to define the mechanisms of granuloma formation and point to specific methods to prevent granuloma formation, which will increase the utility and reduce the risks of this important pain therapy. ..
  44. URINARY BLADDER MUSCARINIC RECEPTOR SUBTYPES
    MICHAEL RUGGIERI; Fiscal Year: 2003
    ..3. To characterize the changes in M2 M3 receptor phosphorylation that may accompany receptor desensitization and receptor up and down regulation. ..
  45. LBP with Radiculopathy: An Inflammatory Response
    JOYCE DELEO; Fiscal Year: 2005
    ..This new knowledge will guide development of novel, non-addictive preventive therapies and treatments for chronic low back pain. ..
  46. GENETIC APPROACH TO CNS REGENERATION RESEARCH
    Oswald Steward; Fiscal Year: 2001
    ....
  47. Alternatives to Opioids for Chronic Pain: Part IV
    Joyce A DeLeo; Fiscal Year: 2010
    ..The results from these multidisciplinary studies may culminate in novel pharmacopeia to treat and prevent chronic neuropathic pain and thus, has the potential for high clinical impact. ..
  48. Stromal Epithelial Interactions in Breast Cancer
    Gerald Cunha; Fiscal Year: 2004
    ..To accomplish these goals we will use tissue recombinant technology, cell and organ culture, immunocytochemistry, and various molecular methodologies. ..
  49. PAIN MODULATION BY ENDOGENOUS CANNABINOIDS
    J Walker; Fiscal Year: 2004
    ..The experiments will determine the peripheral fiber types and the spinal cord neurons and neural pathways that induce the release of anandamide. ..
  50. Mechanisms of uterine vascular adaptation in pregnancy
    Natalia Gokina; Fiscal Year: 2006
    ..abstract_text> ..
  51. Postdoctoral Training Program in Neural Regeneration
    Oswald Steward; Fiscal Year: 2005
    ....
  52. Summer Training Program in Neuroscience
    Oswald Steward; Fiscal Year: 2006
    ..Where appropriate, trainees will be encouraged to present their results at national meetings, and support will be provided for students to attend such meetings. [unreadable] [unreadable]..
  53. Spinal Galanin and its Receptors in Pain Processing
    Tony Yaksh; Fiscal Year: 2005
    ..We believe the outcome of these studies will provide direct evidence for the role played by this spinal peptidergic system in pain and point to the development of novel anti-hyperpathic agents. ..
  54. Use Dependent Plasticity of Spinal Inhibition
    NIRANJALA TILLAKARATNE; Fiscal Year: 2006
    ..This work will lead to better ways of testing the effectiveness of alternative training strategies and associated pharmacological interventions. ..
  55. MEMS-Based High-Frequency Ultrasonic Nozzles for Medical Applications
    CHEN TSAI; Fiscal Year: 2008
    ..The five corresponding research tasks to achieve these aims are: (1) Design and simulation of multiple Fourier horns-based nozzles using a 3-D ANSYS Program, (2) Nozzle fabrication using micro-electromechanical system (MEMS) ..
  56. CONTROL OF SPINAL LOCOMOTOR ACTIVITY BY MONOAMINES
    BRIAN NOGA; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  57. Annual Meeting of the American Pain Society
    Linda Sorkin; Fiscal Year: 2005
    ..Abstracts will be judged on scientific merit and published in The Journal of Pain. We believe that these awards will encourage meeting attendance by trainees. ..
  58. Axon Regeneration after Spinal Cord Injury in Mice
    Oswald Steward; Fiscal Year: 2009
    ..Together, these studies will provide a critical data base regarding the growth capacity of cortico-spinal tract axons in mice, which will be essential for future studies involving genetically modified mice. ..
  59. Cerebral edema in pediatric ketoacidosis
    Nicole Glaser; Fiscal Year: 2009
    ..This initial animal data will form the basis for a randomized clinical trial of interventions for the prevention of CE in children with DKA which will be the main focus of the study. ..
  60. HETEROSPECIFIC CELL/CELL INTERACTIONS IN PROSTATE GROWTH
    Gerald Cunha; Fiscal Year: 2001
    ..Concepts derived from the analysis of basic cellular mechanisms of prostatic growth will be applied to the pathogenesis of BPH. ..
  61. THE CPA: SOMATIC AND AUTONOMIC SYSTEMS
    W Panneton; Fiscal Year: 2004
    ..Understanding the brainstem mechanisms governing he vascular constriction after either of these somatic stimuli may provide a neurological explanation for this. Such knowledge may lead to an understanding of essential hypertension. ..
  62. CELL CELL INTERACTIONS IN PROSTATE CANCER
    Gerald Cunha; Fiscal Year: 2001
    ..These studies should define critical cellular and molecular pathways in both normal and tumorigenic growth of the prostate, and should provide the biological basis of new therapeutic strategies. ..