molluginaceae

Summary

Summary: A plant family of the order Caryophyllales, subclass Caryophyllidae, class Magnoliopsida. Some members contain triterpenoid saponins.

Top Publications

  1. ncbi Complex evolutionary transitions and the significance of c(3)-c(4) intermediate forms of photosynthesis in Molluginaceae
    Pascal Antoine Christin
    Department of Ecology and Evolutionary Biology, Brown University, 80 Waterman St, Box G W, Providence, Rhode Island 02912, USA
    Evolution 65:643-60. 2011
  2. ncbi Recent progress in Glinus oppositifolius research
    Shi Yuan Sheu
    School of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC
    Pharm Biol 52:1079-84. 2014
  3. ncbi A new triterpenoid saponin from Glinus oppositifolius with α-glucosidase inhibitory activity
    Deepak Kumar
    Department of Natural Products, National Institute of Pharmaceutical Education and Research, 4 Raja S C Mullick Road, Jadavpur, Kolkata, India
    Nat Prod Res 27:624-9. 2013
  4. ncbi An in vitro study on the DNA damaging effects of phytochemicals partially isolated from an extract of Glinus lotoides
    Jemal Demma
    Department of Pharmaceutical Biosciences, Division of Toxicology, Uppsala University, Uppsala, Sweden
    Phytother Res 27:507-14. 2013
  5. ncbi Protective effect of Mollugo nudicaulis Lam. on acute liver injury induced by perchloroethylene in experimental rats
    Sundaraj Rajamanikandan
    Department of Bioinformatics, Karpagam University, Coimbatore, India
    Asian Pac J Trop Med 5:862-7. 2012
  6. ncbi Molecular phylogenetic relationships among members of the family Phytolaccaceae sensu lato inferred from internal transcribed spacer sequences of nuclear ribosomal DNA
    J Lee
    International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong Gu, Daejeon, South Korea
    Genet Mol Res 12:4515-25. 2013
  7. ncbi Repeated origin of three-dimensional leaf venation releases constraints on the evolution of succulence in plants
    R Matthew Ogburn
    Department of Ecology and Evolutionary Biology, Brown University, 80 Waterman Street, Box G W, Providence, RI 02912, USA
    Curr Biol 23:722-6. 2013
  8. ncbi Androecial evolution in Caryophyllales in light of a paraphyletic Molluginaceae
    Samuel Brockington
    Department of Plant Sciences, University of Cambridge, Cambridge, CB2 3EA, UK
    Am J Bot 100:1757-78. 2013
  9. ncbi Anticancer activity and nutritional value of extracts of the seed of Glinus lotoides
    Abebe Endale Mengesha
    Laboratory of Future Nanomedicines and Theoretical Chronopharmaceutics, Division of Pharmaceutical Sciences, University of Missouri Kansas City, 64108, USA
    J Nutr Sci Vitaminol (Tokyo) 56:311-8. 2010
  10. ncbi L-(-)-(N-trans-cinnamoyl)-arginine, an acylamino acid from Glinus oppositifolius (L.) Aug. DC
    Poolsak Sahakitpichan
    Chulabhorn Research Institute, Vipavadee Rangsit Highway, Bangkok, Thailand
    Molecules 15:6186-92. 2010

Scientific Experts

  • A Endale
  • Kari T Inngjerdingen
  • R Matthew Ogburn
  • Françoise Benoit-Vical
  • Poolsak Sahakitpichan
  • Pascal Antoine Christin
  • Jemal Demma
  • Shi Yuan Sheu
  • Deepak Kumar
  • Samuel Brockington
  • J Lee
  • Sundaraj Rajamanikandan
  • Ephrem Engidawork
  • Abebe Endale Mengesha
  • J Demma
  • Bikas C Pal
  • Sang Suk Kim
  • Mao Cai Yan
  • Tanusree Biswas
  • Arafa I Hamed
  • A P Ferreira
  • Yi Chih Lei
  • Chun Ching Lin
  • Chun Hsu Yao
  • Tzong Fu Kuo
  • Teshome Leta Aboye
  • Ulf Goransson
  • Hesham El-Seedi
  • Bjorn Hellman
  • S Y Kim
  • Rina Ghosh
  • Patricia dos Santos
  • Vrunda Shah
  • S H Park
  • Beverley Glover
  • M A Ali
  • Louis Ronse De Craene
  • Dominic Sophia
  • Thangaraj Sindhu
  • Paramasivam Ragavendran
  • Velliyur Kanniappan Gopalakrishnan
  • Dhanapal Durgapriya
  • Bi Botti C Youan
  • E Engidawork
  • B Hellman
  • Ji Young Kim
  • Chang Gu Hyun
  • Nam Ho Lee
  • Kaleab Asres
  • Wondwossen Ergetie
  • Tsige Gebre-Mariam
  • Mao Sheng Cheng
  • Qing chun Xu
  • Hong Chen
  • Ying Ke
  • Yang Liu
  • Basudeb Achari
  • Sonia Piacente
  • Wieslaw Oleszek
  • Giuseppina Autore
  • Cosimo Pizza
  • Moumita Gupta
  • Stefania Marzocco
  • C A Salgado
  • L S Gonçalves
  • H C Teixeira
  • F M Teixeira
  • M A C Kaplan
  • G L G Soares
  • Yu Fang Hsu
  • Lean Teik Ng
  • Jenq Jer Yang

Detail Information

Publications25

  1. ncbi Complex evolutionary transitions and the significance of c(3)-c(4) intermediate forms of photosynthesis in Molluginaceae
    Pascal Antoine Christin
    Department of Ecology and Evolutionary Biology, Brown University, 80 Waterman St, Box G W, Providence, Rhode Island 02912, USA
    Evolution 65:643-60. 2011
    ..To study the origin of C(4) photosynthesis, we reconstructed and dated the phylogeny of Molluginaceae, and identified C(4) taxa in the family...
  2. ncbi Recent progress in Glinus oppositifolius research
    Shi Yuan Sheu
    School of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC
    Pharm Biol 52:1079-84. 2014
    Glinus oppositifolius (L.) Aug. DC. (Molluginaceae), a perennial subshrubs herb, grows at low altitudes in the southern part of Taiwan, and is used in traditional Chinese medicine for herpes zoster and herpangina.
  3. ncbi A new triterpenoid saponin from Glinus oppositifolius with α-glucosidase inhibitory activity
    Deepak Kumar
    Department of Natural Products, National Institute of Pharmaceutical Education and Research, 4 Raja S C Mullick Road, Jadavpur, Kolkata, India
    Nat Prod Res 27:624-9. 2013
    ..Compound 1 exhibited the greatest inhibition of the enzyme with IC50 of 127 ± 30 µM. Kinetics study for the compound 1 demonstrated mixed type of inhibition (Ki = 157.9 µM)...
  4. ncbi An in vitro study on the DNA damaging effects of phytochemicals partially isolated from an extract of Glinus lotoides
    Jemal Demma
    Department of Pharmaceutical Biosciences, Division of Toxicology, Uppsala University, Uppsala, Sweden
    Phytother Res 27:507-14. 2013
    ..lotoides...
  5. ncbi Protective effect of Mollugo nudicaulis Lam. on acute liver injury induced by perchloroethylene in experimental rats
    Sundaraj Rajamanikandan
    Department of Bioinformatics, Karpagam University, Coimbatore, India
    Asian Pac J Trop Med 5:862-7. 2012
    ..To evaluate the protective effect of ethanol extract of Mollugo nudicaulis (M. nudicaulis) against perchloroethylene-induced hepatotoxicity...
  6. ncbi Molecular phylogenetic relationships among members of the family Phytolaccaceae sensu lato inferred from internal transcribed spacer sequences of nuclear ribosomal DNA
    J Lee
    International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong Gu, Daejeon, South Korea
    Genet Mol Res 12:4515-25. 2013
    ..internal transcribed spacer of nuclear ribosomal DNA from 11 families (Aizoaceae, Basellaceae, Didiereaceae, Molluginaceae, Nyctaginaceae, Phytolaccaceae s.l...
  7. ncbi Repeated origin of three-dimensional leaf venation releases constraints on the evolution of succulence in plants
    R Matthew Ogburn
    Department of Ecology and Evolutionary Biology, Brown University, 80 Waterman Street, Box G W, Providence, RI 02912, USA
    Curr Biol 23:722-6. 2013
    ..The repeated evolution of 3D venation decouples leaf water storage from hydraulic path length, facilitating the evolutionary exploration of novel phenotypic space...
  8. ncbi Androecial evolution in Caryophyllales in light of a paraphyletic Molluginaceae
    Samuel Brockington
    Department of Plant Sciences, University of Cambridge, Cambridge, CB2 3EA, UK
    Am J Bot 100:1757-78. 2013
    ....
  9. ncbi Anticancer activity and nutritional value of extracts of the seed of Glinus lotoides
    Abebe Endale Mengesha
    Laboratory of Future Nanomedicines and Theoretical Chronopharmaceutics, Division of Pharmaceutical Sciences, University of Missouri Kansas City, 64108, USA
    J Nutr Sci Vitaminol (Tokyo) 56:311-8. 2010
    ..The amount of protein, carbohydrate, fat, ash, moisture, sugar profile and fatty acids further support the nutritional value of the seeds...
  10. ncbi L-(-)-(N-trans-cinnamoyl)-arginine, an acylamino acid from Glinus oppositifolius (L.) Aug. DC
    Poolsak Sahakitpichan
    Chulabhorn Research Institute, Vipavadee Rangsit Highway, Bangkok, Thailand
    Molecules 15:6186-92. 2010
    ..The structure determinations were based on analyses of chemical and spectroscopic methods...
  11. ncbi Potential genotoxicity of plant extracts used in Ethiopian traditional medicine
    J Demma
    Department of Pharmaceutical Biosciences, Division of Toxicology, Uppsala University, Box 594, 751 24 Uppsala, Sweden
    J Ethnopharmacol 122:136-42. 2009
    ..In the present study, hydroalcoholic extracts of Glinus lotoides, Plumbago zeylanica, Rumex steudelii and Thymus schimperi were evaluated for their DNA damaging effects using the comet assay...
  12. ncbi Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria
    Sang Suk Kim
    Department of Chemistry, Cheju National University
    J Gen Appl Microbiol 54:101-6. 2008
    ..Based on these results, we suggest that M. pentaphylla, A. anomala, M. orientalis, and O. japonica are attractive acne-mitigating candidates for topical application...
  13. pmc Granulation by roller compaction and enteric coated tablet formulation of the extract of the seeds of Glinus lotoides loaded on Aeroperl 300 Pharma
    Abebe Endale
    Department of Pharmaceutics, School of Pharmacy, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia
    AAPS PharmSciTech 9:31-8. 2008
    ..8. In addition to controlling the release of the active agents, the enteric coating improved the strength and decreased friability of the core-tablets...
  14. ncbi Immunological and structural properties of a pectic polymer from Glinus oppositifolius
    Kari T Inngjerdingen
    Department of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, Blindern, Oslo, Norway
    Glycobiology 17:1299-310. 2007
    ..The ability of GOA2 to induce secretion of proinflammatory cytokines was examined. Marked upregulations in mRNA for IL-1beta from rat macrophages and IFN-gamma from NK cells were found...
  15. ncbi Immunomodulatory activity of Mollugo verticillata L
    A P Ferreira
    Departamento de Parasitologia, Microbiologia e Imunologia, Universidade Federal de Juiz de Fora, MG, Brazil
    Phytomedicine 10:154-8. 2003
    This article describes the evaluation of immunomodulatory activity of Mollugo verticillata L. (Molluginaceae), a weed plant common in warm and/or wet regions of the American continent...
  16. ncbi Standardisation and physicochemical characterisation of the extracts of seeds of Glinus lotoides
    A Endale
    Department of Pharmaceutics, School of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia
    Pharmazie 59:34-8. 2004
    ..Measurements of angle of repose indicated that all of the extracts exhibit poor flow properties. Compaction studies revealed that extract C has higher compactibility than extracts A and B...
  17. ncbi Hopane-type saponins from Glinus lotoides Linn
    Tanusree Biswas
    Indian Institute of Chemical Biology, Medicinal Chemistry Division, 4, Raja S C Mullick Road, Kolkata 700032, India
    Phytochemistry 66:621-6. 2005
    ..The known compound succulentoside B (7) was also encountered. Their structures were elucidated on the basis of one-and two-dimensional NMR spectroscopic techniques, ESIMS and chemical evidences...
  18. ncbi Hopane-type saponins from the seeds of Glinus lotoides
    Abebe Endale
    Pharmazeutisches Institut, Pharmazeutische Technologie, Auf der Morgenstelle 8, D 72076 Tubingen, Germany
    J Nat Prod 68:443-6. 2005
    ....
  19. ncbi Antiproliferative hopane and oleanane glycosides from the roots of Glinus lotoides
    Arafa I Hamed
    Botany Department, Aswan Faculty of Science, South Valley University, Aswan, Egypt
    Planta Med 71:554-60. 2005
    ..b>Molluginaceae). Their structures were determined by extensive 1D- and 2D-NMR spectroscopy and ESI-MS analysis...
  20. ncbi Bioactive pectic polysaccharides from Glinus oppositifolius (L.) Aug. DC., a Malian medicinal plant, isolation and partial characterization
    Kari Tvete Inngjerdingen
    Department of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, P O Box 1068 Blindern, N 0316 Oslo, Norway
    J Ethnopharmacol 101:204-14. 2005
    ..Both GOA1 and GOA2 were shown to exhibit potent dose-dependent complement fixating activities, and induced chemotaxis of macrophages, T cells and NK cells...
  21. ncbi Quantitative determination of the group of flavonoids and saponins from the extracts of the seeds of Glinus lotoides and tablet formulation thereof by high-performance liquid chromatography
    Abebe Endale
    Department of Pharmaceutical Technology, University of Tubingen, Auf der Morgenstelle 8, 72076 Tubingen, Germany
    J Chromatogr A 1083:32-41. 2005
    ..Accordingly, the purified extract was found to contain 21.3% flavonoids (vicenin-2, 10%) and 25.4% saponins (glinuside G, 14.2%)...
  22. ncbi Synthesis and antitumor activity of two natural N-acetylglucosamine-bearing triterpenoid saponins: lotoidoside D and E
    Mao Cai Yan
    Key Lab of New Drugs Design and Discovery of Liaoning Province, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, PR China
    Bioorg Med Chem Lett 16:4200-4. 2006
    ..Preliminary pharmacological research showed their antitumor activity against HeLa cell...
  23. ncbi In vitro and in vivo antiplasmodial activity of Momordica balsamina alone or in a traditional mixture
    F Benoit-Vical
    Laboratoire de Chimie de Coordination du CNRS, UPR8241, Toulouse, France
    Chemotherapy 52:288-92. 2006
    ..Here we report the study of the in vitro and in vivo antimalarial activity of Momordica balsamina alone or in a traditional mixture used in Niger...
  24. ncbi Toxicological study on Glinus lotoides: a traditionally used taenicidal herb in Ethiopia
    Jemal Demma
    Department of Pharmacology, School of Pharmacy, Addis Ababa University, Ethiopia
    J Ethnopharmacol 111:451-7. 2007
    Seeds of Glinus lotoides L. (Molluginaceae) are used traditionally in the treatment of tapeworm infestation in Ethiopia...
  25. ncbi Anti-inflammatory and hepatoprotective activity of peh-hue-juwa-chi-cao in male rats
    Chun Ching Lin
    Graduate Institute of Natural Products, Kaohsiung Medical University, Taiwan
    Am J Chin Med 30:225-34. 2002
    ....