pseudomonas

Summary

Summary: A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.

Top Publications

  1. pmc Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes
    Geoffrey L Winsor
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada
    Nucleic Acids Res 39:D596-600. 2011
  2. ncbi RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis
    David Mackey
    Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA
    Cell 108:743-54. 2002
  3. pmc Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes
    Geoffrey L Winsor
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada
    Nucleic Acids Res 37:D483-8. 2009
  4. pmc Pseudomonas biofilm matrix composition and niche biology
    Ethan E Mann
    Department of Microbial Infection and Immunity, Department of Microbiology, Center for Microbial Interface Biology, The Ohio State University Medical Center, Columbus, OH 43210, USA
    FEMS Microbiol Rev 36:893-916. 2012
  5. ncbi Biological control of soil-borne pathogens by fluorescent pseudomonads
    Dieter Haas
    Department of Fundamental Microbiology, University of Lausanne, CH 1015 Lausanne, Switzerland
    Nat Rev Microbiol 3:307-19. 2005
  6. doi Small RNAs as regulators of primary and secondary metabolism in Pseudomonas species
    Elisabeth Sonnleitner
    Max F Perutz Laboratories, Department of Microbiology, Immunobiology and Genetics, University of Vienna, Dr Bohrgasse 9, Vienna, Austria
    Appl Microbiol Biotechnol 91:63-79. 2011
  7. pmc Pseudomonas syringae phytotoxins: mode of action, regulation, and biosynthesis by peptide and polyketide synthetases
    C L Bender
    Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, Oklahoma 74078 3032, USA
    Microbiol Mol Biol Rev 63:266-92. 1999
  8. pmc Class 1 integrons and tetracycline resistance genes in alcaligenes, arthrobacter, and Pseudomonas spp. isolated from pigsties and manured soil
    Yvonne Agersø
    Danish Food and Veterinary Research, Section of Antimicrobial Resistance, Bulowsvej 27, 1790 Copenhagen V, Denmark
    Appl Environ Microbiol 71:7941-7. 2005
  9. ncbi Cyclic lipopeptide production by plant-associated Pseudomonas spp.: diversity, activity, biosynthesis, and regulation
    Jos M Raaijmakers
    Laboratory of Phytopathology, Wageningen University, The Netherlands
    Mol Plant Microbe Interact 19:699-710. 2006
  10. ncbi Biofilm formation and cellulose expression among diverse environmental Pseudomonas isolates
    Susanne Ude
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
    Environ Microbiol 8:1997-2011. 2006

Detail Information

Publications387 found, 100 shown here

  1. pmc Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes
    Geoffrey L Winsor
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada
    Nucleic Acids Res 39:D596-600. 2011
    b>Pseudomonas is a metabolically-diverse genus of bacteria known for its flexibility and leading free living to pathogenic lifestyles in a wide range of hosts. The Pseudomonas Genome Database (http://www.pseudomonas...
  2. ncbi RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis
    David Mackey
    Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA
    Cell 108:743-54. 2002
    In Arabidopsis, RPM1 confers resistance against Pseudomonas syringae expressing either of two sequence unrelated type III effectors, AvrRpm1 or AvrB...
  3. pmc Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes
    Geoffrey L Winsor
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada
    Nucleic Acids Res 37:D483-8. 2009
    b>Pseudomonas aeruginosa is a well-studied opportunistic pathogen that is particularly known for its intrinsic antimicrobial resistance, diverse metabolic capacity, and its ability to cause life threatening infections in cystic fibrosis ..
  4. pmc Pseudomonas biofilm matrix composition and niche biology
    Ethan E Mann
    Department of Microbial Infection and Immunity, Department of Microbiology, Center for Microbial Interface Biology, The Ohio State University Medical Center, Columbus, OH 43210, USA
    FEMS Microbiol Rev 36:893-916. 2012
    ..Each of these stages includes reinforcement by, or modulation of, the extracellular matrix. Pseudomonas aeruginosa has been a model organism for the study of biofilm formation...
  5. ncbi Biological control of soil-borne pathogens by fluorescent pseudomonads
    Dieter Haas
    Department of Fundamental Microbiology, University of Lausanne, CH 1015 Lausanne, Switzerland
    Nat Rev Microbiol 3:307-19. 2005
    ..Before engaging in these activities, biocontrol bacteria go through several regulatory processes at the transcriptional and post-transcriptional levels...
  6. doi Small RNAs as regulators of primary and secondary metabolism in Pseudomonas species
    Elisabeth Sonnleitner
    Max F Perutz Laboratories, Department of Microbiology, Immunobiology and Genetics, University of Vienna, Dr Bohrgasse 9, Vienna, Austria
    Appl Microbiol Biotechnol 91:63-79. 2011
    ..Examples of this group in Pseudomonas aeruginosa are the iron-repressible PrrF1 and PrrF2 sRNAs, which repress the translation of genes encoding iron-..
  7. pmc Pseudomonas syringae phytotoxins: mode of action, regulation, and biosynthesis by peptide and polyketide synthetases
    C L Bender
    Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, Oklahoma 74078 3032, USA
    Microbiol Mol Biol Rev 63:266-92. 1999
    ..syringomycin, syringopeptin, tabtoxin, and phaseolotoxin are the most intensively studied phytotoxins of Pseudomonas syringae, and each contributes significantly to bacterial virulence in plants...
  8. pmc Class 1 integrons and tetracycline resistance genes in alcaligenes, arthrobacter, and Pseudomonas spp. isolated from pigsties and manured soil
    Yvonne Agersø
    Danish Food and Veterinary Research, Section of Antimicrobial Resistance, Bulowsvej 27, 1790 Copenhagen V, Denmark
    Appl Environ Microbiol 71:7941-7. 2005
    ..Arthrobacter spp., Alcaligenes spp., Pseudomonas spp., and Corynebacterium glutamicum. The 257 isolates were screened for in-1...
  9. ncbi Cyclic lipopeptide production by plant-associated Pseudomonas spp.: diversity, activity, biosynthesis, and regulation
    Jos M Raaijmakers
    Laboratory of Phytopathology, Wageningen University, The Netherlands
    Mol Plant Microbe Interact 19:699-710. 2006
    ..CLPs) are versatile molecules produced by a variety of bacterial genera, including plant-associated Pseudomonas spp...
  10. ncbi Biofilm formation and cellulose expression among diverse environmental Pseudomonas isolates
    Susanne Ude
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
    Environ Microbiol 8:1997-2011. 2006
    ..A survey of 185 plant-associated, phytopathogenic, soil and river Pseudomonas isolates resulted in 76% producing biofilms at the air-liquid (A-L) interface after selection in static ..
  11. doi DNA sequence-based analysis of the Pseudomonas species
    Magdalena Mulet
    Microbiologia, Departament de Biologia, Edifici Guillem Colom, Universitat de les Illes Balears, Campus UIB, 07122 Palma de Mallorca, Spain
    Environ Microbiol 12:1513-30. 2010
    Partial sequences of four core 'housekeeping' genes (16S rRNA, gyrB, rpoB and rpoD) of the type strains of 107 Pseudomonas species were analysed in order to obtain a comprehensive view regarding the phylogenetic relationships within the ..
  12. doi The virtue of temperance: built-in negative regulators of quorum sensing in Pseudomonas
    Vittorio Venturi
    International Centre for Genetic Engineering and Biotechnology, Padriciano, 99, 34012 Trieste, Italy
    Mol Microbiol 82:1060-70. 2011
    ..The main QS signal molecules produced by Pseudomonas belong to the family of N-acyl-homoserine lactones (AHLs); these are synthesized by a LuxI-family synthase and ..
  13. pmc A second quorum-sensing system regulates cell surface properties but not phenazine antibiotic production in Pseudomonas aureofaciens
    Z Zhang
    Department of Plant Pathology, University of Arizona, Tucson, Arizona 85721, USA
    Appl Environ Microbiol 67:4305-15. 2001
    The root-associated biological control bacterium Pseudomonas aureofaciens 30-84 produces a range of exoproducts, including protease and phenazines...
  14. doi Polyhydroxyalkanoates are essential for maintenance of redox state in the Antarctic bacterium Pseudomonas sp. 14-3 during low temperature adaptation
    Nicolás D Ayub
    Departamento de Quimica Biologica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Intendente Güiraldes 2160, C1428EGA Buenos Aires, Argentina
    Extremophiles 13:59-66. 2009
    ..We have previously shown that phaRBAC genes from the Antarctic bacterium Pseudomonas sp...
  15. ncbi Pseudomonas community structure and antagonistic potential in the rhizosphere: insights gained by combining phylogenetic and functional gene-based analyses
    Rodrigo Costa
    Federal Biological Research Centre for Agriculture and Forestry BBA, Messeweg 11 12, D 38104 Braunschweig, Germany
    Environ Microbiol 9:2260-73. 2007
    The Pseudomonas community structure and antagonistic potential in the rhizospheres of strawberry and oilseed rape (host plants of the fungal phytopathogen Verticillium dahliae) were assessed...
  16. doi Comparative analysis of metabolic networks provides insight into the evolution of plant pathogenic and nonpathogenic lifestyles in Pseudomonas
    Aziz Mithani
    Department of Statistics, University of Oxford, Oxford, United Kingdom
    Mol Biol Evol 28:483-99. 2011
    Plant pathogenic pseudomonads such as Pseudomonas syringae colonize plant surfaces and tissues and have been reported to be nutritionally specialized relative to nonpathogenic pseudomonads...
  17. doi Natural functions of lipopeptides from Bacillus and Pseudomonas: more than surfactants and antibiotics
    Jos M Raaijmakers
    Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands
    FEMS Microbiol Rev 34:1037-62. 2010
    ..This review gives a detailed overview of the versatile functions of lipopeptides in the biology of Pseudomonas and Bacillus species, and highlights their role in competitive interactions with coexisting organisms, ..
  18. doi Annotation and overview of the Pseudomonas savastanoi pv. savastanoi NCPPB 3335 draft genome reveals the virulence gene complement of a tumour-inducing pathogen of woody hosts
    Pablo Rodriguez-Palenzuela
    Centro de Biotecnología y Genómica de Plantas, E T S Ingenieros Agronomos, Universidad Politecnica de Madrid, Campus de Montegancedo, E 28223 Pozuelo de Alarcón, Madrid, Spain
    Environ Microbiol 12:1604-20. 2010
    b>Pseudomonas savastanoi pv. savastanoi is a tumour-inducing pathogen of Olea europaea L. causing olive knot disease...
  19. pmc Biogeography and degree of endemicity of fluorescent Pseudomonas strains in soil
    J C Cho
    Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824, USA
    Appl Environ Microbiol 66:5448-56. 2000
    Fluorescent Pseudomonas strains were isolated from 38 undisturbed pristine soil samples from 10 sites on four continents...
  20. pmc Bacteria in the leaf ecosystem with emphasis on Pseudomonas syringae-a pathogen, ice nucleus, and epiphyte
    S S Hirano
    Department of Plant Pathology, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Microbiol Mol Biol Rev 64:624-53. 2000
    ..This review focuses on the bacterial component of leaf microbial communities, with emphasis on Pseudomonas syringae-a species that participates in leaf ecosystems as a pathogen, ice nucleus, and epiphyte...
  21. pmc New bacterial pathway for 4- and 5-chlorosalicylate degradation via 4-chlorocatechol and maleylacetate in Pseudomonas sp. strain MT1
    Patricia Nikodem
    Department of Environmental Microbiology, GBF German Research Center for Biotechnology, D 38124 Braunschweig, Germany
    J Bacteriol 185:6790-800. 2003
    b>Pseudomonas sp. strain MT1 is capable of degrading 4- and 5-chlorosalicylates via 4-chlorocatechol, 3-chloromuconate, and maleylacetate by a novel pathway...
  22. doi Pseudomonas genomes: diverse and adaptable
    Mark W Silby
    Department of Biology, University of Massachusetts Dartmouth, North Dartmouth, MA, USA
    FEMS Microbiol Rev 35:652-80. 2011
    Members of the genus Pseudomonas inhabit a wide variety of environments, which is reflected in their versatile metabolic capacity and broad potential for adaptation to fluctuating environmental conditions...
  23. ncbi A newly identified regulator is required for virulence and toxin production in Pseudomonas syringae
    T Kitten
    Department of Plant Pathology, University of Wisconsin Madison, 53706, USA
    Mol Microbiol 28:917-29. 1998
    ..In Pseudomonas syringae strain B728a, gacS and gacA are required for lesion formation on bean, as well as for the production ..
  24. pmc Monalysin, a novel ß-pore-forming toxin from the Drosophila pathogen Pseudomonas entomophila, contributes to host intestinal damage and lethality
    Onya Opota
    Global Health Institute, École Polytechnique Fédérale Lausanne EPFL, Lausanne, Switzerland
    PLoS Pathog 7:e1002259. 2011
    b>Pseudomonas entomophila is an entomopathogenic bacterium that infects and kills Drosophila. P...
  25. ncbi A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis
    Feng Shao
    Department of Biological Chemistry, Medical School and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Cell 109:575-88. 2002
    A Yersinia effector known as YopT and a Pseudomonas avirulence protein known as AvrPphB define a family of 19 proteins involved in bacterial pathogenesis...
  26. ncbi Resistance to Pseudomonas syringae conferred by an Arabidopsis thaliana coronatine-insensitive (coi1) mutation occurs through two distinct mechanisms
    A P Kloek
    Department of Biology, Washington University, St Louis, MO 63130, USA
    Plant J 26:509-22. 2001
    ..was isolated in a screen for Arabidopsis thaliana mutants with enhanced resistance to the bacterial pathogen Pseudomonas syringae. This mutant, designated coi1-20, exhibits robust resistance to several P...
  27. doi The plant pathogen Pseudomonas fuscovaginae contains two conserved quorum sensing systems involved in virulence and negatively regulated by RsaL and the novel regulator RsaM
    Maura Mattiuzzo
    International Centre for Genetic Engineering and Biotechnology, Biosafety Outstation, Ca Tron, Treviso, Italy
    Environ Microbiol 13:145-62. 2011
    b>Pseudomonas fuscovaginae is a Gram-negative fluorescent pseudomonad pathogenic towards several plant species. Despite its importance as a plant pathogen, no molecular studies of virulence have thus far been reported...
  28. pmc Complete genome sequence of a beneficial plant root-associated bacterium, Pseudomonas brassicacearum
    Philippe Ortet
    CEA, DSV, IBEB, SBVME, Lab Ecol Microb Rhizosphere and Environ Extrem LEMiRE, Saint Paul lez Durance, F 13108, France
    J Bacteriol 193:3146. 2011
    To shed light on the genetic equipment of the beneficial plant-associated bacterium Pseudomonas brassicacearum, we sequenced the whole genome of the strain NFM421...
  29. ncbi Bacteria killing their own kind: novel bacteriocins of Pseudomonas and other gamma-proteobacteria
    Annabel H A Parret
    Trends Microbiol 10:107-12. 2002
  30. doi Pseudomonas protegens sp. nov., widespread plant-protecting bacteria producing the biocontrol compounds 2,4-diacetylphloroglucinol and pyoluteorin
    Alban Ramette
    Plant Pathology Group, Institute of Integrative Biology, Swiss Federal Institute of Technology ETH, CH 8092 Zurich, Switzerland
    Syst Appl Microbiol 34:180-8. 2011
    Fluorescent Pseudomonas strains producing the antimicrobial secondary metabolite 2,4-diacetylphloroglucinol (Phl) play a prominent role in the biocontrol of plant diseases...
  31. ncbi Proteomic analysis of the sarcosine-insoluble outer membrane fraction of Pseudomonas aeruginosa responding to ampicilin, kanamycin, and tetracycline resistance
    Xuanxian Peng
    Center for Proteomics, Department of Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People s Republic of China
    J Proteome Res 4:2257-65. 2005
    Nosocomial wound infections by antibiotic-resistant Pseudomonas aeruginosa strains have increasing importance in hospitals. Outer membrane proteins of the bacterium have strong influence on its resistance to antibiotics...
  32. ncbi GacS-dependent production of 2R, 3R-butanediol by Pseudomonas chlororaphis O6 is a major determinant for eliciting systemic resistance against Erwinia carotovora but not against Pseudomonas syringae pv. tabaci in tobacco
    Song Hee Han
    Agricultural Plant Stress Research Center, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 500 757, Korea
    Mol Plant Microbe Interact 19:924-30. 2006
    Root colonization by a plant-beneficial rhizobacterium, Pseudomonas chlororaphis O6, induces disease resistance in tobacco against leaf pathogens Erwinia carotovora subsp. carotovora SCC1, causing soft-rot, and Pseudomonas syringae pv...
  33. pmc The Arabidopsis NHL3 gene encodes a plasma membrane protein and its overexpression correlates with increased resistance to Pseudomonas syringae pv. tomato DC3000
    Anne Varet
    Department of Stress and Developmental Biology, Institute of Plant Biochemistry, D 06120, Halle Saale, Germany
    Plant Physiol 132:2023-33. 2003
    ..transgenic NHL3-overexpressing plant lines, a clear correlation between increased resistance to virulent Pseudomonas syringae pv. tomato DC3000 and enhanced NHL3 transcript levels was seen...
  34. pmc Evaluation of the Hodge test and the imipenem-EDTA double-disk synergy test for differentiating metallo-beta-lactamase-producing isolates of Pseudomonas spp. and Acinetobacter spp
    K Lee
    Department of Laboratory Medicine, Research Institute of Bacterial Resistance, and BK21 Project for Medical Sciences, Yonsei University College of Medicine, Seodaemun Ku, Seoul 120 752, Korea
    J Clin Microbiol 41:4623-9. 2003
    ..Further evaluation of the test is required for the detection of other types of MBL-producing gram-negative bacilli...
  35. ncbi Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila
    Nicolas Vodovar
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, 91198 Gif sur Yvette, France
    Nat Biotechnol 24:673-9. 2006
    b>Pseudomonas entomophila is an entomopathogenic bacterium that, upon ingestion, kills Drosophila melanogaster as well as insects from different orders. The complete sequence of the 5...
  36. pmc Transcriptome profiling defines a novel regulon modulated by the LysR-type transcriptional regulator MexT in Pseudomonas aeruginosa
    Zhe Xian Tian
    BIOMERIT Research Centre, Department of Microbiology, University College Cork, Cork, Ireland
    Nucleic Acids Res 37:7546-59. 2009
    The LysR-family regulator MexT modulates the expression of the MexEF-OprN efflux system in the human pathogen Pseudomonas aeruginosa...
  37. ncbi DNA relatedness among the pathovars of Pseudomonas syringae and description of Pseudomonas tremae sp. nov. and Pseudomonas cannabina sp. nov. (ex Sutic and Dowson 1959)
    L Gardan
    Institut National de la Recherche Agronomique, Pathologie Végétale et Phytobactériologie, Beaucouze, France
    Int J Syst Bacteriol 49:469-78. 1999
    A total of 48 pathovars of Pseudomonas syringae and eight related species were studied by DNA-DNA hybridization (S1 nuclease method) and ribotyping. The existence of nine discrete genomospecies was indicated...
  38. pmc HrpZ(Psph) from the plant pathogen Pseudomonas syringae pv. phaseolicola binds to lipid bilayers and forms an ion-conducting pore in vitro
    J Lee
    Leibniz Institut für Pflanzenbiochemie, Weinberg 3, D 06120 Halle, Germany
    Proc Natl Acad Sci U S A 98:289-94. 2001
    ..Here, we show that the hrpZ gene product from the bean halo-blight pathogen, Pseudomonas syringae pv. phaseolicola (HrpZ(Psph)), is secreted in an hrp-dependent manner in P. syringae pv...
  39. pmc Complete nucleotide sequence and organization of the atrazine catabolic plasmid pADP-1 from Pseudomonas sp. strain ADP
    B Martinez
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, St Paul, Minnesota 55108, USA
    J Bacteriol 183:5684-97. 2001
    The complete 108,845-nucleotide sequence of catabolic plasmid pADP-1 from Pseudomonas sp. strain ADP was determined...
  40. doi Iron uptake and metabolism in pseudomonads
    Pierre Cornelis
    Microbial Interactions, Department of Molecular and Cellular Interactions, VIB and Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium
    Appl Microbiol Biotechnol 86:1637-45. 2010
    ..Some are plant pathogens (Pseudomonas syringae) which have to survive on the surface of leaves while others can colonize the rhizosphere or survive ..
  41. pmc Identification of a putative alternate sigma factor and characterization of a multicomponent regulatory cascade controlling the expression of Pseudomonas syringae pv. syringae Pss61 hrp and hrmA genes
    Y Xiao
    Department of Botany, University of Maryland, College Park 20742
    J Bacteriol 176:1025-36. 1994
    The Pseudomonas syringae hrp and hrmA genes controlling pathogenicity and elicitation of the hypersensitive response and the avr genes controlling host range have been shown previously to be regulated by carbon, nitrogen, pH, osmolarity, ..
  42. ncbi Influence of fusaric acid on phenazine-1-carboxamide synthesis and gene expression of Pseudomonas chlororaphis strain PCL1391
    E Tjeerd van Rij
    Leiden University, Institute of Biology, The Netherlands
    Microbiology 151:2805-14. 2005
    Production of the antifungal metabolite phenazine-1-carboxamide (PCN) by Pseudomonas chlororaphis strain PCL1391 is essential for the suppression of tomato foot and root rot caused by the soil-borne fungus F. oxysporum f. sp...
  43. ncbi Structural and mechanistic similarities of 6-phosphogluconate and 3-hydroxyisobutyrate dehydrogenases reveal a new enzyme family, the 3-hydroxyacid dehydrogenases
    J W Hawes
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, 46202 5122, USA
    FEBS Lett 389:263-7. 1996
    ..amino acid sequence homology with 6-phosphogluconate dehydrogenase, D-phenylserine dehydrogenase from Pseudomonas syringae, and a number of hypothetical proteins encoded by genes of microbial origin...
  44. ncbi Cultivation-independent analysis of Pseudomonas species in soil and in the rhizosphere of field-grown Verticillium dahliae host plants
    Rodrigo Costa
    Federal Biological Research Centre for Agriculture and Forestry BBA, Messeweg 11 12, D 38104 Braunschweig, Germany
    Environ Microbiol 8:2136-49. 2006
    Despite their importance for rhizosphere functioning, rhizobacterial Pseudomonas spp. have been mainly studied in a cultivation-based manner...
  45. ncbi Characterization of the salA, syrF, and syrG regulatory genes located at the right border of the syringomycin gene cluster of Pseudomonas syringae pv. syringae
    Shi En Lu
    Department of Plant Pathology, Washington State University, Pullman 99164 6430, USA
    Mol Plant Microbe Interact 15:43-53. 2002
    Sequence analysis of the right border of the syr gene cluster of Pseudomonas syringae pv. syringae strain B301D revealed the presence of the salA gene 8,113 bp downstream of syrE...
  46. pmc Human- and plant-pathogenic Pseudomonas species produce bacteriocins exhibiting colicin M-like hydrolase activity towards peptidoglycan precursors
    Hélène Barreteau
    Universite Paris Sud, Institut de Biochimie et Biophysique Moleculaire et Cellulaire, UMR 8619, Orsay F 91405, France
    J Bacteriol 191:3657-64. 2009
    ..similarity to the C-terminal domain of Escherichia coli colicin M were identified in the genomes of some Pseudomonas species, namely, P. aeruginosa, P. syringae, and P. fluorescens...
  47. ncbi Grouping of phenol hydroxylase and catechol 2,3-dioxygenase genes among phenol- and p-cresol-degrading Pseudomonas species and biotypes
    Merike Merimaa
    Department of Genetics, Institute of Molecular and Cell Biology, University of Tartu, Riia 23, 51010 Tartu, Estonia
    Arch Microbiol 186:287-96. 2006
    ..Our data suggest that few central routes for the degradation of phenolic compounds may emerge in bacteria as a result of the combination of genetically diverse catabolic genes...
  48. pmc Isolation and characterization of novel bacterial strains exhibiting ligninolytic potential
    Luaine Bandounas
    B Basic, Julianalaan 67, 2628 BC Delft, The Netherlands
    BMC Biotechnol 11:94. 2011
    ..In this study, soil bacteria were isolated by enrichment on Kraft lignin and evaluated for their ligninolytic potential as a source of novel enzymes for waste lignin valorization...
  49. pmc Computational prediction of the Crc regulon identifies genus-wide and species-specific targets of catabolite repression control in Pseudomonas bacteria
    Patrick Browne
    BIOMERIT Research Centre, Microbiology Department University College Cork, Ireland
    BMC Microbiol 10:300. 2010
    Catabolite repression control (CRC) is an important global control system in Pseudomonas that fine tunes metabolism in order optimise growth and metabolism in a range of different environments. The mechanism of CRC in Pseudomonas spp...
  50. ncbi Interactions in the tomato rhizosphere of two Pseudomonas biocontrol strains with the phytopathogenic fungus Fusarium oxysporum f. sp. radicis-lycopersici
    Annouschka Bolwerk
    Leiden University, Institute of Molecular Plant Sciences, Clusius Laboratory, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
    Mol Plant Microbe Interact 16:983-93. 2003
    ..sp. radicis-lycopersici causes foot and root rot of tomato plants, which can be controlled by the bacteria Pseudomonas fluorescens WCS365 and P. chlororaphis PCL1391...
  51. doi Biosynthesis and characterization of poly(3-hydroxydodecanoate) by β-oxidation inhibited mutant of Pseudomonas entomophila L48
    Ah Leum Chung
    MOE Key Lab of Protein Sciences, Department of Biological Sciences and Biotechnology, School of Life Sciences, Tsinghua University, Beijing 100084, China
    Biomacromolecules 12:3559-66. 2011
    A medium-chain-length (MCL) polyhydroxyalkanoates (PHAs) producer Pseudomonas entomophila L48 was investigated for microbial production of 3-hydroxydodecanote homopolymer...
  52. ncbi The cytochrome cbb3 from Pseudomonas stutzeri displays nitric oxide reductase activity
    E Forte
    Department of Biochemical Sciences and CNR Centre of Molecular Biology, University of Rome 'La Sapienza, Rome, Italy
    Eur J Biochem 268:6486-91. 2001
    The cytochrome cbb3 is an isoenzyme in the family of cytochrome c oxidases. This protein purified from Pseudomonas stutzeri displays a cyanide-sensitive nitric oxide reductase activity (Vmax=100+/-9 mol NO x mol cbb3(-1) x min(-1) and Km=..
  53. pmc Pseudomonas chromosomal replication origins: a bacterial class distinct from Escherichia coli-type origins
    T W Yee
    Department of Biology, University of California, San Diego, La Jolla 92093
    Proc Natl Acad Sci U S A 87:1278-82. 1990
    The bacterial origins of DNA replication have been isolated from Pseudomonas aeruginosa and Pseudomonas putida...
  54. pmc X-ray structure of a hydroxylase-regulatory protein complex from a hydrocarbon-oxidizing multicomponent monooxygenase, Pseudomonas sp. OX1 phenol hydroxylase
    Matthew H Sazinsky
    Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Biochemistry 45:15392-404. 2006
    ..Comparisons between the ToMOH and PHH structures provide insights into their substrate regiospecificities...
  55. ncbi Antibiotic production by bacterial biocontrol agents
    Jos M Raaijmakers
    Department of Plant Sciences, Wageningen University, The Netherlands
    Antonie Van Leeuwenhoek 81:537-47. 2002
    ..This review presents recent advances in our understanding of antibiotic production by bacterial biocontrol agents and their role in microbial interactions...
  56. doi Biodegradation of the organophosphorus insecticide diazinon by Serratia sp. and Pseudomonas sp. and their use in bioremediation of contaminated soil
    Mariusz Cycoń
    Department of Microbiology, Faculty of Pharmacy, Medical University of Silesia, Jagiellonska 4, 41 200 Sosnowiec, Poland
    Chemosphere 76:494-501. 2009
    ..strains were screened and identified by MIDI-FAME profiling as Serratia liquefaciens, Serratia marcescens and Pseudomonas sp...
  57. doi A secondary metabolite acting as a signalling molecule controls Pseudomonas entomophila virulence
    Isabelle Vallet-Gely
    Centre de Genetique Moleculaire, CNRS, 91198 Gif sur Yvette, France
    Cell Microbiol 12:1666-79. 2010
    b>Pseudomonas entomophila is an entomopathogenic bacterium that is lethal to Drosophila melanogaster within 1-2 days of ingestion of high doses. Flies orally infected with P...
  58. pmc PseudoMLSA: a database for multigenic sequence analysis of Pseudomonas species
    Antoni Bennasar
    Departament de Biologia, Microbiologia, Universitat de les Illes Balears, Campus UIB, 07122 Palma de Mallorca, Spain
    BMC Microbiol 10:118. 2010
    The genus Pseudomonas comprises more than 100 species of environmental, clinical, agricultural, and biotechnological interest...
  59. ncbi A new metabolic link between fatty acid de novo synthesis and polyhydroxyalkanoic acid synthesis. The PHAG gene from Pseudomonas putida KT2440 encodes a 3-hydroxyacyl-acyl carrier protein-coenzyme a transferase
    B H Rehm
    Institut fur Mikrobiologie, Westfalische Wilhelms Universitat Munster, Corrensstrabetae 3, D 48149, Munster, Germany
    J Biol Chem 273:24044-51. 1998
    ..link between fatty acid de novo synthesis and polyhydroxyalkanoic acid (PHA) synthesis, we isolated mutants of Pseudomonas putida KT2440 deficient in this metabolic route...
  60. ncbi Phylogenetic analysis of Pseudomonas syringae pathovars suggests the horizontal gene transfer of argK and the evolutionary stability of hrp gene cluster
    H Sawada
    National Institute of Agro Environmental Sciences, 3 1 1 Kannondai, Tsukuba, Ibaraki 305 8604, Japan
    J Mol Evol 49:627-44. 1999
    b>Pseudomonas syringae are differentiated into approximately 50 pathovars with different plant pathogenicities and host specificities...
  61. pmc Scarless and sequential gene modification in Pseudomonas using PCR product flanked by short homology regions
    Rubing Liang
    School of Life Science and Technology, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200240, China
    BMC Microbiol 10:209. 2010
    ..The procedure consists of electroporating a polymerase chain reaction (PCR) fragment containing antibiotic cassette flanked by homology regions to the target locus into a strain that can express the lambda Red proteins (Gam, Bet, Exo)...
  62. pmc The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000
    C Robin Buell
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Proc Natl Acad Sci U S A 100:10181-6. 2003
    We report the complete genome sequence of the model bacterial pathogen Pseudomonas syringae pathovar tomato DC3000 (DC3000), which is pathogenic on tomato and Arabidopsis thaliana. The DC3000 genome (6...
  63. pmc Genetic diversity, recombination and cryptic clades in Pseudomonas viridiflava infecting natural populations of Arabidopsis thaliana
    Erica M Goss
    Department of Ecology and Evolution, University of Chicago, Chicago, Illinois 60615, USA
    Genetics 169:21-35. 2005
    ..b>Pseudomonas viridiflava is a common natural bacterial pathogen of Arabidopsis thaliana, for which pathogen defense genes ..
  64. ncbi Comparison of avrD alleles from Pseudomonas syringae pv. glycinea
    L W Keith
    Department of Plant Pathology, University of Nebraska, Lincoln 68583 0722, USA
    Mol Plant Microbe Interact 10:416-22. 1997
    Avirulence gene D alleles resided on indigenous plasmids in races 0, 2, 3, 4, 5, and 6 of Pseudomonas syringae pv. glycinea (Psg), but the allele in race 1 appeared to be chromosomal...
  65. ncbi Phenazine-1-carboxylic acid is negatively regulated and pyoluteorin positively regulated by gacA in Pseudomonas sp. M18
    Yihe Ge
    College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai 200240, PR China
    FEMS Microbiol Lett 237:41-7. 2004
    The biosynthesis of antimicrobial metabolites is controlled by the GacS/GacA two-component regulatory system in Pseudomonas species...
  66. ncbi Interactions between plants and beneficial Pseudomonas spp.: exploiting bacterial traits for crop protection
    Jesús Mercado-Blanco
    Departamento de Protección de Cultivos, Instituto de Agricultura Sostenible, Consejo Superior de Investigaciones Cientificas, Apartado 4084, 14080 Cordoba, Spain
    Antonie Van Leeuwenhoek 92:367-89. 2007
    Specific strains of fluorescent Pseudomonas spp. inhabit the environment surrounding plant roots and some even the root interior...
  67. ncbi Nucleotide sequence, functional characterization and evolution of pFKN, a virulence plasmid in Pseudomonas syringae pathovar maculicola
    Laurence Rohmer
    Department of Biology, Coker Hall 108, CB 3280, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3280, USA
    Mol Microbiol 47:1545-62. 2003
    b>Pseudomonas syringae pv. maculicola strain M6 (Psm M6) carries the avrRpm1 gene, encoding a type III effector, on a 40 kb plasmid, pFKN. We hypothesized that this plasmid might carry additional genes required for pathogenesis on plants...
  68. ncbi Immobilized Pseudomonas cepacia lipase for biodiesel fuel production from soybean oil
    H Noureddini
    Department of Chemical Engineering, 207h Othmer Hall, University of Nebraska Lincoln, Lincoln, NE 68588 0643, USA
    Bioresour Technol 96:769-77. 2005
    ..Of the nine lipases that were tested in the initial screening, lipase PS from Pseudomonas cepacia resulted in the highest yield of alkyl esters...
  69. doi Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut
    Sveta Chakrabarti
    Global Health Institute, School of Life Science, Ecole Polytechnique Federale de Lausanne, Switzerland
    Cell Host Microbe 12:60-70. 2012
    ..Here, we analyze how the entomopathogenic bacterium Pseudomonas entomophila induces irreversible damage to the Drosophila gut. We find that P...
  70. ncbi Phylogeny of the genus Pseudomonas: intrageneric structure reconstructed from the nucleotide sequences of gyrB and rpoD genes
    S Yamamoto
    Marine Biotechnology Institute, Kamaishi Laboratories, Kamaishi City, Iwate 026, Japan
    Microbiology 146:2385-94. 2000
    Phylogenetic analysis of the genus Pseudomonas: was conducted by using the combined gyrB and rpoD nucleotide sequences of 31 validly described species of Pseudomonas: (a total of 125 strains)...
  71. pmc PBAD-based shuttle vectors for functional analysis of toxic and highly regulated genes in Pseudomonas and Burkholderia spp. and other bacteria
    Dongru Qiu
    Department of Biochemistry and Microbiology, Joan C Edwards School of Medicine at Marshall University, Huntington, West Virginia 25755 9320, USA
    Appl Environ Microbiol 74:7422-6. 2008
    We report the construction of a series of Escherichia-Pseudomonas broad-host-range expression vectors utilizing the P(BAD) promoter and the araC regulator for routine cloning, conditional expression, and analysis of tightly controlled ..
  72. pmc Genome sequence analyses of Pseudomonas savastanoi pv. glycinea and subtractive hybridization-based comparative genomics with nine pseudomonads
    Mingsheng Qi
    Department of Crop Sciences, University of Illinois at Urbana Champaign, Urbana, Illinois, United States of America
    PLoS ONE 6:e16451. 2011
    Bacterial blight, caused by Pseudomonas savastanoi pv. glycinea (Psg), is a common disease of soybean...
  73. pmc Identification and characterization of catabolic para-nitrophenol 4-monooxygenase and para-benzoquinone reductase from Pseudomonas sp. strain WBC-3
    Jun Jie Zhang
    Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China
    J Bacteriol 191:2703-10. 2009
    b>Pseudomonas sp. strain WBC-3 utilizes para-nitrophenol (PNP) as a sole source of carbon, nitrogen, and energy. In order to identify the genes involved in this utilization, we cloned and sequenced a 12...
  74. pmc Homology and functional similarity of an hrp-linked pathogenicity locus, dspEF, of Erwinia amylovora and the avirulence locus avrE of Pseudomonas syringae pathovar tomato
    A J Bogdanove
    Department of Plant Pathology, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 95:1325-30. 1998
    ..A BLAST search revealed similarity in the dspE gene to a partial sequence of the avrE locus of Pseudomonas syringae pathovar tomato. The entire avrE locus was sequenced...
  75. doi Carbon catabolite repression in Pseudomonas : optimizing metabolic versatility and interactions with the environment
    Fernando Rojo
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia, CSIC, Madrid, Spain
    FEMS Microbiol Rev 34:658-84. 2010
    ..This review summarizes the regulatory mechanisms responsible for CCR in the bacteria of the genus Pseudomonas, which can live in many different habitats...
  76. pmc Quantitative nature of Arabidopsis responses during compatible and incompatible interactions with the bacterial pathogen Pseudomonas syringae
    Yi Tao
    Torrey Mesa Research Institute, Syngenta Research and Technology, San Diego, California 92121, USA
    Plant Cell 15:317-30. 2003
    ..mRNA expression profiling using an Affymetrix GeneChip to study Arabidopsis responses to the bacterial pathogen Pseudomonas syringae...
  77. ncbi Molecular determinants of rhizosphere colonization by Pseudomonas
    B J Lugtenberg
    Leiden University, Institute of Molecular Plant Sciences, Clusius Laboratory Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
    Annu Rev Phytopathol 39:461-90. 2001
    ..b>Pseudomonas, one of the best root colonizers, is therefore used as a model root colonizer...
  78. doi Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered
    Matthieu Barret
    BIOMERIT Research Centre, Department of Microbiology, University College Cork, Cork, Ireland
    Microbiology 157:1726-39. 2011
    ..To assess diversity and predict function associated with different T6SSs, comparative genomic analysis of 34 Pseudomonas genomes was performed...
  79. pmc nag genes of Ralstonia (formerly Pseudomonas) sp. strain U2 encoding enzymes for gentisate catabolism
    N Y Zhou
    School of Biological Sciences, University of Wales, Bangor, Gwynedd LL57 2UW, Wales, United Kingdom
    J Bacteriol 183:700-8. 2001
    ..upper pathway operon described for conversion of naphthalene to salicylate found in the NAH7 plasmid of Pseudomonas putida PpG7...
  80. pmc Utilization of acyl-homoserine lactone quorum signals for growth by a soil pseudomonad and Pseudomonas aeruginosa PAO1
    Jean J Huang
    Department of Biology, California Institute of Technology, Pasadena, California 91125, USA
    Appl Environ Microbiol 69:5941-9. 2003
    ..Here we describe the isolation of a soil bacterium, Pseudomonas strain PAI-A, that degrades 3-oxododecanoyl-homoserine lactone (3OC12HSL) and other long-acyl, but not short-..
  81. doi Bacteriophages of Pseudomonas
    Pieter Jan Ceyssens
    Department of Biosystems, Katholieke Universiteit Leuven, Kasteelpark Arenberg 21, bus 2462, B 3001 Leuven, Belgium
    Future Microbiol 5:1041-55. 2010
    b>Pseudomonas species and their bacteriophages have been studied intensely since the beginning of the 20th century, due to their ubiquitous nature, and medical and ecological importance...
  82. ncbi Lipopeptide phytotoxins produced by Pseudomonas syringae pv. syringae: comparison of the biosurfactant and ion channel-forming activities of syringopeptin and syringomycin
    M L Hutchison
    Department of Plant Pathology, Washington State University, Pullman 99164 6430, USA
    Mol Plant Microbe Interact 10:347-54. 1997
    The phytopathogenic bacterium Pseudomonas syringae pv. syringae produces two classes of necrosis-inducing lipodepsipeptide toxins commonly referred to as the syringomycins and syringopeptins...
  83. ncbi Molecular phylogeny of the genus Pseudomonas based on rpoB sequences and application for the identification of isolates
    Lyneda Ait Tayeb
    Unité de Biodiversité des Bactéries Pathogènes Emergentes, INSERM Unit 389, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Res Microbiol 156:763-73. 2005
    Phylogenetic relationships within the genus Pseudomonas were examined by comparing partial (about 1000 nucleotides) rpoB gene sequences...
  84. pmc Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model
    Peter Liehl
    Centre de Genetique Moleculaire, Centre National de la Rercheche Scientifique, Gif sur Yvette, France
    PLoS Pathog 2:e56. 2006
    ..a natural context, we investigated the interactions between Drosophila and a newly identified entomopathogen, Pseudomonas entomophila. Flies orally infected with P...
  85. ncbi Phenazine compounds in fluorescent Pseudomonas spp. biosynthesis and regulation
    Dmitri V Mavrodi
    Department of Plant Pathology, Washington State University, Pullman, Washington 99164 6430, USA
    Annu Rev Phytopathol 44:417-45. 2006
    ..50 pigmented, heterocyclic nitrogen-containing secondary metabolites synthesized by some strains of fluorescent Pseudomonas spp. and a few other bacterial genera...
  86. pmc Oligomerization of type III secretion proteins PopB and PopD precedes pore formation in Pseudomonas
    Guy Schoehn
    Laboratoire de Virologie Molèculaire Structurale, Grenoble, France
    EMBO J 22:4957-67. 2003
    b>Pseudomonas aeruginosa is the agent of opportunistic infections in immunocompromised individuals and chronic respiratory illnesses in cystic fibrosis patients...
  87. ncbi Regulation of antibiotic production in root-colonizing Peudomonas spp. and relevance for biological control of plant disease
    Dieter Haas
    Institut de Microbiologie Fondamentale, Universite de Lausanne, CH 1015 Lausanne, Switzerland Email
    Annu Rev Phytopathol 41:117-53. 2003
    ..One challenge in future biocontrol research involves development of new strategies to overcome the broad toxicity and lack of antifungal specificity displayed by most biocontrol antibiotics studied so far...
  88. pmc Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial
    Daniel G Lee
    Department of Molecular Biology, Massachusetts General Hospital, Cambridge Street, Boston, Massachusetts 02114, USA
    Genome Biol 7:R90. 2006
    b>Pseudomonas aeruginosa is a ubiquitous environmental bacterium and an important opportunistic human pathogen. Generally, the acquisition of genes in the form of pathogenicity islands distinguishes pathogenic isolates from nonpathogens...
  89. pmc A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants
    Paula Hauck
    Department of Energy Plant Research Laboratory and Department of Plant Biology, Michigan State University, East Lansing, MI 48824, USA
    Proc Natl Acad Sci U S A 100:8577-82. 2003
    ..However, the identity of such suppressors has remained elusive. We discovered that the Pseudomonas syringae TTSS down-regulated the expression of a set of Arabidopsis genes encoding putatively secreted cell ..
  90. pmc Altering the ratio of phenazines in Pseudomonas chlororaphis (aureofaciens) strain 30-84: effects on biofilm formation and pathogen inhibition
    V S R K Maddula
    Department of Plant Sciences, Division of Plant Pathology and Microbiology, The University of Arizona, Tucson, AZ 85721, USA
    J Bacteriol 190:2759-66. 2008
    b>Pseudomonas chlororaphis strain 30-84 is a plant-beneficial bacterium that is able to control take-all disease of wheat caused by the fungal pathogen Gaeumannomyces graminis var. tritici...
  91. ncbi Bacterial lipases: an overview of production, purification and biochemical properties
    R Gupta
    Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, 110 021 New Delhi, India
    Appl Microbiol Biotechnol 64:763-81. 2004
    ..Some important lipase-producing bacterial genera include Bacillus, Pseudomonas and Burkholderia...
  92. ncbi Regulation of quorum sensing in Pseudomonas
    Vittorio Venturi
    International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
    FEMS Microbiol Rev 30:274-91. 2006
    ..In Gram-negative bacteria, the most common signal molecules are acylated homoserine lactones. Several Pseudomonas species produce acylated homoserine lactones that control important functions including pathogenicity and plant ..
  93. ncbi PCR amplification of hydrogen cyanide biosynthetic locus hcnAB in Pseudomonas spp
    M Svercel
    Plant Pathology, Institute of Integrative Biology, ETH Zurich, CH 8092 Zurich, Switzerland
    J Microbiol Methods 70:209-13. 2007
    ..9 and 3.5 cells per PCR reaction tube. RFLP analysis revealed 13 allele combinations among selected 2,4-diacetylphloroglucinol-producing (Phl(+))HCN(+), and 13 alleles in Phl(-) HCN(+) strains from a global collection...
  94. ncbi Identification and characterization of the acyclic terpene utilization gene cluster of Pseudomonas citronellolis
    Karin Förster-Fromme
    Institut fur Mikrobiologie, Universitat Stuttgart, Stuttgart, Germany
    FEMS Microbiol Lett 264:220-5. 2006
    The catabolism of citronellol and geraniol [acyclic terpene utilization (Atu) pathway] was investigated in Pseudomonas citronellolis. A 13...
  95. ncbi A high-throughput screen of cell-death-inducing factors in Nicotiana benthamiana identifies a novel MAPKK that mediates INF1-induced cell death signaling and non-host resistance to Pseudomonas cichorii
    Yoshihiro Takahashi
    Iwate Biotechnology Research Center, 22 174 4, Narita, Kitakami, Iwate 024 0003, Japan
    Plant J 49:1030-40. 2007
    ..Furthermore, the resistance of N. benthamiana to a non-host pathogen Pseudomonas cichorii was compromised in NbMKK1-silenced plants...
  96. pmc Global regulation by gidA in Pseudomonas syringae
    Thomas G Kinscherf
    Department of Plant Pathology, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Bacteriol 184:2281-6. 2002
    Analysis of two virulence mutants of Pseudomonas syringae B728a revealed that the Tn 5 sites of insertion were within the gidA open reading frame (ORF)...
  97. ncbi Malikia granosa gen. nov., sp. nov., a novel polyhydroxyalkanoate- and polyphosphate-accumulating bacterium isolated from activated sludge, and reclassification of Pseudomonas spinosa as Malikia spinosa comb. nov
    Stefan Spring
    DSMZ Deutsche Sammlung von Mikroorganismen und Zellkulturen, Mascheroder Weg 1b, D 38124 Braunschweig, Germany
    Int J Syst Evol Microbiol 55:621-9. 2005
    ..The closest relatives in reconstructed phylogenetic trees were Pseudomonas spinosa, Macromonas bipunctata and Hydrogenophaga species...
  98. pmc Highly different levels of natural transformation are associated with genomic subgroups within a local population of Pseudomonas stutzeri from soil
    Johannes Sikorski
    Genetics Section, Department of Biology, University of Oldenburg, D 26111 Oldenburg, Germany
    Appl Environ Microbiol 68:865-73. 2002
    A highly sensitive and specific PCR-based method of monitoring 16S rRNA genes of Pseudomonas stutzeri was developed for searching P. stutzeri DNA in environmental samples...
  99. doi Mathematical modelling for predicting the growth of Pseudomonas spp. in poultry under variable temperature conditions
    Radovan Gospavic
    Wessex Institute of Technology, Ashurst, UK
    Int J Food Microbiol 127:290-7. 2008
    ..under variable temperature conditions was implemented and calibrated using raw data for microbial growth of Pseudomonas spp. in poultry under aerobic conditions...
  100. ncbi Biodegradation of phenanthrene by Pseudomonas sp. strain PP2: novel metabolic pathway, role of biosurfactant and cell surface hydrophobicity in hydrocarbon assimilation
    Y Prabhu
    Biotechnology Group, BJM School of Biosciences and Bioengineering, Indian Institute of Technology Bombay, 400 076 Powai, Mumbai, India
    Appl Microbiol Biotechnol 61:342-51. 2003
    b>Pseudomonas sp. strain PP2 isolated in our laboratory efficiently metabolizes phenanthrene at 0.3% concentration as the sole source of carbon and energy...
  101. doi Purification and characterization of chitinases and chitosanases from a new species strain Pseudomonas sp. TKU015 using shrimp shells as a substrate
    San Lang Wang
    Graduate Institute of Life Sciences, Tamkang University, 151 Ying chuan Road, Tamsui 251, Taiwan
    Carbohydr Res 343:1171-9. 2008
    A chitinase (CHT1) and a chitosanase (CHS1) were purified from the culture supernatant of Pseudomonas sp. TKU015 with shrimp shell wastes as the sole carbon and nitrogen source...

Research Grants74

  1. Biofilm Formation And P. aeruginosa infection of the eye
    Michael Zegans; Fiscal Year: 2006
    ..b>Pseudomonas aeruginosa (PA) is one of the most common causes of bacterial keratitis...
  2. Sutureless Laparoscopic Partial Nephrectomy Using Laser Tissue Welding: Preclinic
    Yasmin Wadia; Fiscal Year: 2013
    ..wounds of drug- resistant super bugs like Methicillin-Resistant Staphylococcus aureus (MRSA), Streptococcus pyogenes and Pseudomonas aeruginosa. Fibro-optic capable: Minimally invasive laparoscopic &robotic applications.
  3. Targeting superbugs: discovery and development of new broad-spectrum lipopeptides
    Jian Li; Fiscal Year: 2013
    ..Numerous hospitals worldwide have experienced outbreaks of infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, Enterobacter species, Enterococcus faecium and ..
  4. Biochemistry and Function of a Novel Bacterial Photosensory Two-Component System
    MELISSA MARKS; Fiscal Year: 2010
    ..Related photosensor kinases are found in human and plant pathogens such as Brucella melitensis, Pseudomonas syringae, and Xanthomonas campestris...
  5. Novel Bioconjugate Vaccines to Prevent Staphylococcus aureus Infection
    JEAN CLAIRE LEE; Fiscal Year: 2013
    ..aureus capsule type 5 polysaccharide (CP5) vaccine covalently linked to the carrier protein EPA (nontoxic Pseudomonas aeruginosa exoprotein A)...
  6. Mechanism Underlying Nitrite Sensitivity of Mucoid Pseudomonas in COPD
    Daniel J Hassett; Fiscal Year: 2013
    ..COPD) that often suffer from airway infection by opportunistic bacteria, the most prevalent of which is Pseudomonas aeruginosa (PA)...
  7. The Electricidal Effect, a Novel Anti-Biofilm Strategy
    Robin Patel; Fiscal Year: 2013
    ..first submission demonstrated that electrical currents of 20 to 2000 <A substantially reduced established Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis biofilms, a phenomenon we termed the "..
  8. Photodynamic Therapy of Localized Infections
    Michael R Hamblin; Fiscal Year: 2013
    ..synergistically combine with a PDT regimen mediated by a fullerene and white light to save mice from dying in a Pseudomonas wound infection model...
  9. Optimization of Neoglycoside Antibiotics for Nosocomial Pathogens and Select Agen
    Arnold Louie; Fiscal Year: 2013
    ..With Pseudomonas aeruginosa and Acinetobacter spp...
  10. DlaT as a transcriptional regulator in non-replicating Mycobacterium tuberculosis
    Ruslana Bryk; Fiscal Year: 2012
    ..DlaT binds RNA polymerase;DlaT in Bacillus is a transcriptional regulator for sporulation and DlaT in Pseudomonas controls transcription of type III secretion system regulatory operon;DlaT inhibitors only kill Mtb when Mtb is ..
  11. Inhibitors of isoprenoid synthesis for antibacterial therapy
    Donald T Moir; Fiscal Year: 2013
    DESCRIPTION: Pseudomonas aeruginosa is a common and extremely virulent cause of serious infections in immune- compromised/suppressed patients (e.g...
  12. Use of Phosphodiesterase Inhibitors to Evaluate the Pathobiology of CF
    JENNIFER L TAYLOR-COUSAR; Fiscal Year: 2013
    ..and its downstream effects, including disordered glycosylation, predisposition to adherence by Pseudomonas aeruginosa and consequent inflammation...
  13. Analogs of GTP as novel inhibitors of bacterial c-di-GMP-synthesizing enzymes
    George E Wright; Fiscal Year: 2010
    ..by NMR and LCMS methods;2, test GTP analogs for their ability to inhibit cyclization of GTP to c-di- GMP by the Pseudomonas aeruginosa DGC "PA3702";a coupled assay measuring pyrophosphate release and a HPLC assay measuring product ..
  14. Mechanism of Translation Elongation Factor 2 Inhibition by Bacterial Toxins
    Terri Goss Kinzy; Fiscal Year: 2010
    Toxins produced by Corynebacterium diphtheriae (diphtheria toxin) and Pseudomonas aeruginosa (exotoxin A) both result in host cell death by the inhibition of protein synthesis...
  15. ENZYMOLOGY OF ANTIBIOTIC RESISTANCE
    Richard Armstrong; Fiscal Year: 2009
    ..genomically encoded resistance proteins are extant in several select human pathogens, for example, (FosA) in Pseudomonas aeruginosa, (FosB) in Staphylococcus aureus and Bacillus anthracis, and (FosX) in Brucella melitensis, Listeria ..
  16. MNEI/SerpinB1: A modulator of innate pulmonary defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2010
    ..The mnei deficient mice fail to clear Pseudomonas aeruginosa and have increased proinflammatory cytokines and depletion of surfactant protein-D (SP-D), a known ..
  17. ROLE OF MUC1 IN THE GENESIS OF ALLERGIC ASTHMA
    Kwang Chul Kim; Fiscal Year: 2010
    ..Recently we found that it is a receptor for Pseudomonas aeruginosa and binding of bacteria was mediated through flagellin resulting in tyrosine phosphorylation of its ..
  18. Mechanisms of adaptive immunity to P. aeruginosa in the lung
    Gregory P Priebe; Fiscal Year: 2013
    b>Pseudomonas aeruginosa is an important cause of serious infections in humans with a predilection for lung infections in the form of either acute pneumonia in hospitalized patients (usually associated with mechanical ventilation) or ..
  19. X-ray Studies of Sugar-Modifying Enzymes
    Hazel Holden; Fiscal Year: 2013
    ..The quite rare sugar, D-ManNAc3NAcA, has been isolated from the B-band O-antigen of the opportunistic bacterium Pseudomonas aeruginosa, a major source of nosocomial infections and in the A-band trisaccharide of the bacterium Bordetella ..
  20. Cyclic AMP Signaling in Pseudomonas aeruginosa Virulence
    Matthew C Wolfgang; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa is an opportunistic human pathogen that is responsible for nearly 10% of hospital-acquired infections and is the primary cause of morbidity and mortality in cystic fibrosis ..
  21. Mechanisms to restrain social cheating from quorum sensing in Pseudomonas aerugin
    AJAI DANDEKAR; Fiscal Year: 2013
    ..career award is for support to transition to a career of independent investigation in the field of Pseudomonas aeruginosa quorum sensing...
  22. Counter-Regulation of TLR-Driven Mucosal Inflammation
    Erik P Lillehoj; Fiscal Year: 2010
    ..disease characterized by mucus hypersecretion, reduced mucociliary clearance of inhaled bacteria, particularly Pseudomonas aeruginosa (PA), and chronic airway inflammation...
  23. Bacterial Immunosuppression: Host Target Identification Through Chemical Probes
    Kim D Janda; Fiscal Year: 2013
    ..With respect to Pseudomonas aeruginosa, N-3- oxo-dodecanoyl-L-homoserine lactone (C12) and N-butanoyl-L-homoserine lactone are utilized by ..
  24. Novel biofilm polymicrobial infection-resistant implants for otologic application
    Paul Stoodley; Fiscal Year: 2010
    ..We have demonstrated in Phase I that we can suppress biofilm formation and planktonic growth of Pseudomonas aeruginosa and Staphylococcus aureus for an extended period of time...
  25. LIPID A MODIFICATION SYSTEMS IN GRAM-NEGATIVE BACTERIA
    Pei Zhou; Fiscal Year: 2012
    ..Bacteria of this kind, which include all strains of Escherichia coli, Salmonella, Pseudomonas, and Francisella, contain an outer membrane that makes them impermeable to certain dyes and antibiotics...
  26. Regulation of NETosis in antibacterial lung defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2013
    ..from failure to eradicate bacterial (Streptococcus pneumonia, Haemophilus influenza, Staphylococcus aureus, Pseudomonas aeruginosa) and viral (rhinovirus, influenza virus) infections are responsible for a tremendous burden of ..
  27. Structure and Mechanism of SAM-responsive Riboswitches
    Robert T Batey; Fiscal Year: 2013
    ..control in a number of medically important pathogens including Listeria monocytogenes, Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis making them of great interest as novel targets for designing ..
  28. Exploiting deep ocean biology for biomedical discovery
    David C Rowley; Fiscal Year: 2011
    ..clinical strains of multiple drug resistant Staphylococcus aureus, Acinetobacter baumannii, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae...
  29. Polymicrobial interactions in the lung.
    JENNIFER MELINDA BOMBERGER; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa is an opportunistic pathogen and an important pathogen in patients with chronic obstructive pulmonary disorder (COPD), community acquired pneumonia (CAP), ventilator-associated ..
  30. Mechanisms of Pseudomonas Resistance to Membrane Permeabilization by SP-A
    Gee W Lau; Fiscal Year: 2012
    ..Recently, we have reported that SP-A also directly kills Pseudomonas aeruginosa (PA) in a macrophage-independent manner, by increasing the permeability of bacterial membranes...
  31. Cytoskeletal Keratins in Epithelial Immunity to Bacterial Keratitis
    K P CONNIE TAM; Fiscal Year: 2013
    ..their structural interactions with bacterial membranes, and by identifying their bacterial receptors on Pseudomonas aeruginosa, a major corneal pathogen...
  32. Regulation of Streptomyces differentiation and antibiotic production by SoxR
    Monica Chander; Fiscal Year: 2010
    ..This has been confirmed in Pseudomonas aeruginosa where SoxR senses endogenous antibiotics and controls the expression of genes involved in their ..
  33. Challenges in beta-Lactamase Mediated Resistance
    Robert A Bonomo; Fiscal Year: 2013
    ..Acinetobacter baumannii, and Pseudomonas aeruginosa...
  34. Molecular mechanisms of pathogen recognition by the Nod-like receptor NLRC4
    Fayyaz S Sutterwala; Fiscal Year: 2012
    Project Summary Pseudomonas aeruginosa causes a variety of acute infections, such as ventilator-associated pneumonias, burn superinfections, neutropenic bacteremia, and medical device-related infections. In addition, P...
  35. Vaccine Immunotoxin and Radioimmunotherapy of Primary and Metastatic CNS Tumors
    Darell D Bigner; Fiscal Year: 2013
    ..Targeted immunotherapy with monoclonal antibodies (MAbs) or their fragments armed with Astatine 211 or Pseudomonas exotoxin for the treatment of NM or GBM is proposed in Projects 1 and 3...
  36. Mechanisms of trauma and hemorrhage-induced impairment of innate immunity
    Xiao Di Tan; Fiscal Year: 2013
    ..we will study whether hemorrhage-induced alteration of Atg12 is associated with increase in susceptibility to Pseudomonas aeruginosa infection in lungs...
  37. Interactions between P. aeruginosa and autophagy in Airway epithelial cells
    INDHIRA H DE LA ROSA; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The goal of our research proposal is to understand the interactions of Pseudomonas aeruginosa (P...
  38. Pathogensis of Bacterial corneal infection
    Gerald B Pier; Fiscal Year: 2013
    ..Specifically, this application will focus on infections caused by Pseudomonas aeruginosa and Staphylococcus aureus...
  39. Boosting Innate Immunity Through HIF to Treat Antibiotic-Resistant Infections
    ROBERT ALAN SHALWITZ; Fiscal Year: 2013
    ..knockout mice will be used to assess the role of the transcriptional control pathway in control of MRSA and Pseudomonas infections in skin, skin wounds, and pneumonia models of infection...
  40. Cell Based Therapies for Cystic Fibrosis
    Tracey L Bonfield; Fiscal Year: 2012
    ..The morbidities are associated with inefficient resolution of pulmonary infection with Pseudomonas aeruginosa and the ensuing inflammatory response...
  41. Innovative technologies to effectively treat Multi-drug resistant and/or biofilm-
    Jie Wen; Fiscal Year: 2010
    ..baumannii, Klebsiella pneumoniae, methicillin-resistant Staphylococcus aureus, and multi-drug resistant Pseudomonas aeruginosa...
  42. Mechanisms of flagellin-induced protection against microbial keratitis
    Fu Shin X Yu; Fiscal Year: 2013
    ..corneal innate immunity and render resistance to a broad spectrum of keratitis causing pathogens, including Pseudomonas aeruginosa, Candida albicans and Aspergillus fumigates...
  43. Polymicrobial Interactions in the Lung
    JENNIFER MELINDA BOMBERGER; Fiscal Year: 2013
    b>Pseudomonas aeruginosa is an opportunistic pathogen and an important pathogen in patients with chronic obstructive pulmonary disorder (COPD), community acquired pneumonia (CAP), ventilator-associated pneumonia (VAP), non-CF ..
  44. Host-associated regulation of P. aeruginosa colonization and virulence
    Deborah A Hogan; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa is among the most dangerous Gram-negative opportunistic pathogens. In the compromised lung, P...
  45. Molecular Basis of Bacterial Quorum Sensing Gene Regulation
    MAIR E CHURCHILL; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Opportunistic infections by Pseudomonas aeruginosa are a major cause of death in cystic fibrosis patients and immune-compromised individuals...
  46. Pathogen-Specific Regulation of Protein Assembly
    ALLEN BERNARD REITZ; Fiscal Year: 2010
    ..enterocolitica to Plasmodium falciparum, Pseudomonas aeruginosa, Vibrio cholerae, and Toxoplasma gondii...
  47. Genes Mediating Innate Immune Suppression by Hypercapnia in Mammals and Flies
    PETER H SPORN; Fiscal Year: 2013
    ..and human macrophages, and in vivo using adult Drosophila and lung inflammatory cells obtained from mice with Pseudomonas aeruginosa pneumonia...
  48. Diphthamide biosynthesis
    Hening Lin; Fiscal Year: 2012
    ..unmodified histidine residue) is specifically recognized by bacterial toxins, including diphtheria toxin and Pseudomonas exotoxin A...
  49. Identifying novel anti-infectives by high through-put screening in whole animals
    Frederick M Ausubel; Fiscal Year: 2013
    ..To establish proof-of-principle, we seek funding for discovering new anti-infectives against Pseudomonas aeruginosa, one of several gram-negative bacteria that have recently emerged in a multi-drug resistant form for ..
  50. CELLULAR AND MOLECULAR BIOLOGY OF CHOLESTEATOMA
    RICHARD ARTHUR CHOLE; Fiscal Year: 2013
    ..the mechanisms of bacterial-host interactions in the pathogenesis and virulence of cholesteatomas infected with Pseudomonas aeruginosa (PA)...
  51. CAP37 and ocular inflammation
    HELOISE ANNE PEREIRA; Fiscal Year: 2011
    ..for host defense in ocular infection we will use CAP37 and its bioactive peptides in a murine model of Pseudomonas aeruginosa keratitis to determine in vivo efficacy...
  52. Augmentation of Innate Anti-Microbial Immunity by TLR4 Agonists
    Edward R Sherwood; Fiscal Year: 2013
    ..receptor 4 (TLR4) agonist monophosphoryl lipid A (MPLA) is effective in improving innate host resistance to Pseudomonas aeruginosa burn wound sepsis in mice...
  53. Regulation of Pore Formation by Type III Secretion System
    Gloria I Viboud; Fiscal Year: 2010
    ..and enteropathogenic Escherichia coli as well agents causing severe pneumonia, like the opportunistic bacteria Pseudomonas aeruginosa, or the deadly Yersinia pestis. Interestingly, Y...
  54. Antimicrobial Phototherapy of Antibiotic Resistant Chronic Sinusitis
    MERRILL ABRAHAM BIEL; Fiscal Year: 2011
    ..Numerous studies have reported the presence of antibiotic resistant Pseudomonas aerugenosa, Hemophilus influenza, Streptococcus pneumoniae and Staphylococcus aureus biofilms in the sinuses of ..
  55. Aminoglycoside potentiators for P. aeruginosa therapy
    Donald T Moir; Fiscal Year: 2013
    DESCRIPTION: Pseudomonas aeruginosa is a common cause of serious infections in patients with immune deficiency (e.g., HIV and cancer), cystic fibrosis (CF), on mechanical ventilation or with burn wounds. While P...
  56. Stomate-based innate immunity against bacterial infection in Arabidopsis
    Maeli Melotto; Fiscal Year: 2012
    ..Specifically, stomata close in response to Escherichia coli O157:H7 and Pseudomonas syringae pv. tomato (Pst) DC3000 or bacterial PAMPs...
  57. BIOSYNTHESIS AND FUNCTION OF LIPOPOLYSACCHARIDES
    Pei Zhou; Fiscal Year: 2013
    ..Bacteria of this kind, which include all strains of Escherichia coli, Salmonella, Pseudomonas, and Francisella, contain an outer membrane that makes them impermeable to certain dyes and antibiotics...
  58. Understanding of a Family of Bacterial Transcription Factors
    Hwan Youn; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: The CRP homologs found in bacterial pathogens such as Pseudomonas aeruginosa and Listeria monocytogenes act as virulence factors...
  59. Mechanism of heme regulation of a P. aeruginosa non-coding RNA
    AMANDA GAIL OGLESBY-SHERROUSE; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa is an opportunistic pathogen that causes severe infection in compromised individuals, including neutropenic cancer patients and individuals with cystic fibrosis (CF)...
  60. Probing localiztion, interactions, and effector properties of Shigella lpaD
    NICHOLAS EUGENE DICKENSON; Fiscal Year: 2010
    ..with numerous other important pathogens such as Yersinia pestis (plague), Salmonella (gastroenteritis), and Pseudomonas aeruginosa (lung infection) utilize the type III secretion system (TTSS) as a means of subverting the normal ..
  61. The role of host endogenous small RNAs in innate immunity
    Hailing Jin; Fiscal Year: 2013
    ..lsiRNAs, and clustered hc-siRNAs that are particularly regulated by various strains of the bacterium Pseudomonas syringae. Predicted target genes of these small RNAs will be validated and subjected to functional analysis...
  62. Hypercapnia and neutrophil function in pulmonary host defense
    Khalilah L Gates; Fiscal Year: 2013
    ..Furthermore, prolonged hypercapnia in the murine Pseudomonas aeruginosa pneumonia model suggests that hypercapnia leads to a decrease in bacterial clearance and increased ..
  63. Characterization of a bacteriophage tubulin involved in viral replication
    JOSEPH A POGLIANO; Fiscal Year: 2013
    ..We recently discovered a divergent tubulin-like cytoskeletal protein, PhuZ, encoded by the very large (317 kb) Pseudomonas chlororaphis bacteriophage, 201?2-1...
  64. WEILL CORNELL PROGRAM OF EXCELLENCE IN GENE THERAPY
    Ronald Crystal; Fiscal Year: 2005
    ..Rafii); Project 3*- Immunization against Pseudomonas aeruginosa by capsid modified Ad vectors expressing Pseudomonas OprF (S...
  65. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Maragakis; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Multidrug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa, Acinetobacter species, and Klebsiella pneumoniae are emerging pathogens that are increasingly the cause of a variety ..
  66. Quercetin Treatment of Airway Inflammation
    MARC HERSHENSON; Fiscal Year: 2006
    ..cells, and on two mouse models of airways disease, cockroach allergen sensitization (mimicking asthma) and Pseudomonas endobronchial infection (mimicking cystic fibrosis and chronic bronchitis)...
  67. Pseudomonas aeruginosa genomic islands and virulence factors
    VANDERLENE LIU KUNG; Fiscal Year: 2011
    ..b>Pseudomonas aeruginosa is an environmentally ubiquitous bacterium that causes disease in both plants and animals, including ..
  68. Etiology, Epidemiology, and Clinical Outcomes of Health Care Associated Pneumonia
    Karl Madaras Kelly; Fiscal Year: 2009
    ..identify risk factors for MDR bacteria including Methicillin-Resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, compared to non-MDR bacteria and develop models that accurately identify patients infected with MDR...
  69. Impact of Fluoroquinolone resistance on Pseudomonas virulence and patient outcome
    Annie Wong Beringer; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa (PA) is a bacterium that poses an immediate threat to public health because of its leading role in causing nosocomial infections, emergence of multidrug-resistance, virulence ..
  70. Stringent control of virulence gene expression in Pseudomonas aeruginosa
    Martin Schuster; Fiscal Year: 2009
    Chronic infections by the opportunistic pathogen Pseudomonas aeruginosa are the major cause of morbidity in patients suffering from cystic fibrosis (CF). In the CF lung, P...
  71. PSEUDOMONAS 1999--BIOTECHNOLOGY AND PATHOGENESIS
    JOANNA GOLDBERG; Fiscal Year: 1999
    b>Pseudomonas 1999-Seventh International Congress on Pseudomonas: Biotechnology and Pathogenesis is to be held September 1-5, 1999 at the Hyatt Regency Maui, Hawaii...
  72. PSEUDOMONAS EYE INFECTION - AN EXPERIMENTAL MODEL
    Richard Berk; Fiscal Year: 1992
    b>Pseudomonas aeruginosa is an opportunistic bacterial pathogen which produces a number of toxic substances able to cause necrotic central corneal ulcerations...
  73. Hyperacidification and Pseudomonas infections in CF
    Vojo Deretic; Fiscal Year: 2006
    ..The main cause of high morbidity and mortality in CF are the recurring Pseudomonas aeruginosa infections and associated inflammation...
  74. REGULATION OF PSEUDOMONAS INDUCED LUNG INFLAMMATION
    Christopher Wilson; Fiscal Year: 2003
    ..commonly develops in early infancy and then progresses, particularly following acquisition of infection with Pseudomonas aeruginosa...