oxygen

Summary

Summary: An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.

Top Publications

  1. Linninger A, Gould I, Marrinan T, Hsu C, Chojecki M, Alaraj A. Cerebral microcirculation and oxygen tension in the human secondary cortex. Ann Biomed Eng. 2013;41:2264-84 pubmed publisher
    The three-dimensional spatial arrangement of the cortical microcirculatory system is critical for understanding oxygen exchange between blood vessels and brain cells...
  2. Stacpoole S, Webber D, Bilican B, Compston A, Chandran S, Franklin R. Neural precursor cells cultured at physiologically relevant oxygen tensions have a survival advantage following transplantation. Stem Cells Transl Med. 2013;2:464-72 pubmed publisher
    Traditionally, in vitro stem cell systems have used oxygen tensions that are far removed from the in vivo situation. This is particularly true for the central nervous system, where oxygen (O2) levels range from 8% at the pia to 0...
  3. Moser S, Bensaddek D, Ortmann B, Maure J, Mudie S, Blow J, et al. PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192. Dev Cell. 2013;26:381-92 pubmed publisher
    ..Because PHD activity is sensitive to oxygen levels and certain byproducts of the tricarboxylic acid cycle, PHDs act as sensors of the cell's metabolic state...
  4. Yuan Y, Yuan T, Wang D, Tang J, Zhou S. Sewage sludge biochar as an efficient catalyst for oxygen reduction reaction in an microbial fuel cell. Bioresour Technol. 2013;144:115-20 pubmed publisher
    ..The electrochemical analyses display that the prepared biochars are active for catalyzing oxygen reduction reaction (ORR)...
  5. Fredericks W, Yin H, Lal P, Puthiyaveettil R, Malkowicz S, Fredericks N, et al. Ectopic expression of the TERE1 (UBIAD1) protein inhibits growth of renal clear cell carcinoma cells: altered metabolic phenotype associated with reactive oxygen species, nitric oxide and SXR target genes involved in cholesterol and lipid metabolism. Int J Oncol. 2013;43:638-52 pubmed publisher
    ..Furthermore, TERE1 expression increased mitochondrial oxygen consumption and hydrogen production, oxidative stress and NO production...
  6. Kadouri D, Tran A. Measurement of predation and biofilm formation under different ambient oxygen conditions using a simple gasbag-based system. Appl Environ Microbiol. 2013;79:5264-71 pubmed publisher
    ..The aim of this study was to evaluate the ability of the predators to prey in different oxygen environments...
  7. Chen J, Michan S, Juan A, Hurst C, Hatton C, Pei D, et al. Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy. Angiogenesis. 2013;16:985-92 pubmed publisher
    ..deacetylase, in mediating the response of ischemic neurons to regulate vascular regrowth in a mouse model of oxygen-induced ischemic retinopathy (OIR). We found that Sirt1 is highly induced in the avascular ischemic retina in OIR...
  8. Kapadia V, Chalak L, Sparks J, Allen J, Savani R, Wyckoff M. Resuscitation of preterm neonates with limited versus high oxygen strategy. Pediatrics. 2013;132:e1488-96 pubmed publisher
    To determine whether a limited oxygen strategy (LOX) versus a high oxygen strategy (HOX) during delivery room resuscitation decreases oxidative stress in preterm neonates...
  9. Koritzinsky M, Levitin F, van den Beucken T, Rumantir R, Harding N, Chu K, et al. Two phases of disulfide bond formation have differing requirements for oxygen. J Cell Biol. 2013;203:615-27 pubmed publisher
    ..b>Oxygen can serve as the electron acceptor in vitro, but its role in vivo remains unknown...

More Information

Publications98

  1. Forristal C, Christensen D, Chinnery F, Petruzzelli R, Parry K, Sanchez Elsner T, et al. Environmental oxygen tension regulates the energy metabolism and self-renewal of human embryonic stem cells. PLoS ONE. 2013;8:e62507 pubmed publisher
    ..These data suggest that environmental O2 regulates energy metabolism and is intrinsic to the self-renewal of hESCs. ..
  2. Peng C, Liao W, Chen Y, Wu C, Tung Y. A microfluidic cell culture array with various oxygen tensions. Lab Chip. 2013;13:3239-45 pubmed publisher
    b>Oxygen tension plays an important role in regulating various cellular functions in both normal physiology and disease states...
  3. Hirayama R, Ito A, Noguchi M, Matsumoto Y, Uzawa A, Kobashi G, et al. OH radicals from the indirect actions of X-rays induce cell lethality and mediate the majority of the oxygen enhancement effect. Radiat Res. 2013;180:514-23 pubmed publisher
    ..Therefore, the indirect action on cell killing was enhanced by oxygen during X irradiation in both cell lines tested...
  4. Liu X, Tong J, Zweier J, Follmer D, Hemann C, Ismail R, et al. Differences in oxygen-dependent nitric oxide metabolism by cytoglobin and myoglobin account for their differing functional roles. FEBS J. 2013;280:3621-31 pubmed publisher
    The endogenous vasodilator nitric oxide (NO) is metabolized in tissues in an oxygen-dependent manner. In skeletal and cardiac muscle, high concentrations of myoglobin (Mb) function as a potent NO scavenger...
  5. Gorlin Y, Lassalle Kaiser B, Benck J, Gul S, Webb S, Yachandra V, et al. In situ X-ray absorption spectroscopy investigation of a bifunctional manganese oxide catalyst with high activity for electrochemical water oxidation and oxygen reduction. J Am Chem Soc. 2013;135:8525-34 pubmed publisher
    ..situ XAS measurements on a bifunctional manganese oxide (MnOx) catalyst with high electrochemical activity for the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER)...
  6. Ellerby G, Smith C, Zou F, Scott P, Soller B. Validation of a spectroscopic sensor for the continuous, noninvasive measurement of muscle oxygen saturation and pH. Physiol Meas. 2013;34:859-71 pubmed publisher
    ..provide an assessment of the adequacy of tissue perfusion through the simultaneous determination of muscle oxygen saturation (SmO2) and muscle pH (pHm)...
  7. Ricci A, Poccia N, Campi G, Coneri F, Caporale A, Innocenti D, et al. Multiscale distribution of oxygen puddles in 1/8 doped YBa2Cu3O6.67. Sci Rep. 2013;3:2383 pubmed publisher
    ..X-ray diffraction and neutron scattering experiments used to investigate y oxygen dopants in YBa2Cu3O6+y lack of spatial resolution...
  8. Pichler G, Binder C, Avian A, Beckenbach E, Schmölzer G, Urlesberger B. Reference ranges for regional cerebral tissue oxygen saturation and fractional oxygen extraction in neonates during immediate transition after birth. J Pediatr. 2013;163:1558-63 pubmed publisher
    To define reference ranges for regional cerebral tissue oxygen saturation (crSO2) and regional cerebral fractional tissue oxygen extraction (cFTOE) during the first 15 minutes after birth in neonates requiring no medical support...
  9. Kasterstein E, Strassburger D, Komarovsky D, Bern O, Komsky A, Raziel A, et al. The effect of two distinct levels of oxygen concentration on embryo development in a sibling oocyte study. J Assist Reprod Genet. 2013;30:1073-9 pubmed publisher
    ..05. Implantation, pregnancy and live birth rates are higher, and more good quality embryos are available for transfer and freezing with reduced rather than with atmospheric oxygen concentrations during embryo incubation.
  10. Gleichmann T, Diensthuber R, Möglich A. Charting the signal trajectory in a light-oxygen-voltage photoreceptor by random mutagenesis and covariance analysis. J Biol Chem. 2013;288:29345-55 pubmed publisher
    ..the molecular bases underpinning these processes, we analyzed signal reception and processing in the dimeric light-oxygen-voltage (LOV) blue light receptor YF1 that serves as a paradigm for the widespread Per-ARNT-Sim (PAS) signal ..
  11. Zhang L, Su F, Buizer S, Lu H, Gao W, Tian Y, et al. A dual sensor for real-time monitoring of glucose and oxygen. Biomaterials. 2013;34:9779-88 pubmed publisher
    A dual glucose and oxygen sensor in a polymer format was developed...
  12. Batchelor T, Gerstner E, Emblem K, Duda D, Kalpathy Cramer J, Snuderl M, et al. Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation. Proc Natl Acad Sci U S A. 2013;110:19059-64 pubmed publisher
    ..nonresponders early in the course of this expensive and potentially toxic form of therapy, and these results may provide new insight into the selection of glioblastoma patients most likely to benefit from anti-VEGF treatments. ..
  13. Brooks M, Neelam S, Cammarata P. Lenticular mitoprotection. Part B: GSK-3? and regulation of mitochondrial permeability transition for lens epithelial cells in atmospheric oxygen. Mol Vis. 2013;19:2451-67 pubmed
    ..phosphorylation, the means by which GSK-3? influences mitoprotection in cultured human lens epithelial (HLE-B3) cells and normal, secondary cultures of bovine lens epithelial cells, maintained in atmospheric oxygen, was investigated.
  14. Wang D, Chen X, Evans D, Yang W. Well-dispersed Co3O4/Co2MnO4 nanocomposites as a synergistic bifunctional catalyst for oxygen reduction and oxygen evolution reactions. Nanoscale. 2013;5:5312-5 pubmed publisher
    ..derived from a single-source CoMn-layered double hydroxide precursor, exhibit excellent bifunctional oxygen electrode activities for both oxygen reduction and evolution reactions, which can be attributed to the large ..
  15. Wu J, Yang H. Platinum-based oxygen reduction electrocatalysts. Acc Chem Res. 2013;46:1848-57 pubmed publisher
    An efficient oxygen reduction reaction (ORR) offers the potential for clean energy generation in low-temperature, proton-exchange membrane fuel cells running on hydrogen fuel and air...
  16. Chung D, Chung Y, Jung N, Choi K, Sung Y. Correlation between platinum nanoparticle surface rearrangement induced by heat treatment and activity for an oxygen reduction reaction. Phys Chem Chem Phys. 2013;15:13658-63 pubmed publisher
    ..By changing the heat treatment environment, we confirmed the correlation between the oxygen reduction activity and the effect of surface oxide and the degree of surface rearrangement of Pt nanoparticles...
  17. Mielke J. Susceptibility to oxygen-glucose deprivation is reduced in acute hippocampal slices from euthermic Syrian golden hamsters relative to slices from Sprague-Dawley rats. Neurosci Lett. 2013;553:13-7 pubmed publisher
    ..Slices from each species were subjected to oxygen-glucose deprivation (OGD; a commonly used in vitro model of ischaemia), and their viability examined after a ..
  18. Zhang C, Mahmood N, Yin H, Liu F, Hou Y. Synthesis of phosphorus-doped graphene and its multifunctional applications for oxygen reduction reaction and lithium ion batteries. Adv Mater. 2013;25:4932-7 pubmed publisher
    ..for the synthesis of phosphorus-doped graphene, which exhibits remarkable electrocatalytic activity towards the oxygen reduction reaction and enhances the electrochemical performance as an anode material for lithium ion batteries...
  19. Clanton T, Hogan M, Gladden L. Regulation of cellular gas exchange, oxygen sensing, and metabolic control. Compr Physiol. 2013;3:1135-90 pubmed publisher
    ..Regarding exercise, the issues discussed relate to the O2 sensitivity of metabolic rate, O2 kinetics in exercise, and influences of available O2 on glycolysis and lactate production. ..
  20. Ukkonen K, Veijola J, Vasala A, Neubauer P. Effect of culture medium, host strain and oxygen transfer on recombinant Fab antibody fragment yield and leakage to medium in shaken E. coli cultures. Microb Cell Fact. 2013;12:73 pubmed publisher
    ..Maximum productivity in fed-batch-like conditions and in autoinduction medium is achieved under sufficiently oxygen-limited conditions, and lower aeration also promotes increased Fab accumulation into extracellular medium...
  21. Semenza G. Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. Annu Rev Pathol. 2014;9:47-71 pubmed publisher
    Hypoxia-inducible factors (HIFs) are transcriptional activators that function as master regulators of oxygen homeostasis, which is disrupted in disorders affecting the circulatory system and in cancer...
  22. Englund E, Langham M, Li C, Rodgers Z, Floyd T, Mohler E, et al. Combined measurement of perfusion, venous oxygen saturation, and skeletal muscle T2* during reactive hyperemia in the leg. J Cardiovasc Magn Reson. 2013;15:70 pubmed publisher
    The function of the peripheral microvascular may be interrogated by measuring perfusion, tissue oxygen concentration, or venous oxygen saturation (SvO2) recovery dynamics following induced ischemia...
  23. Bizzarro M, Li F, Katz K, Shabanova V, Ehrenkranz R, Bhandari V. Temporal quantification of oxygen saturation ranges: an effort to reduce hyperoxia in the neonatal intensive care unit. J Perinatol. 2014;34:33-8 pubmed publisher
    ..A multidisciplinary group was established to evaluate oxygen exposure in our neonatal intensive care unit...
  24. Babbin A, Keil R, Devol A, Ward B. Organic matter stoichiometry, flux, and oxygen control nitrogen loss in the ocean. Science. 2014;344:406-8 pubmed publisher
    ..The variable ratios between denitrification and anammox previously observed in the ocean are thus attributable to localized variations in OM quality and quantity and do not necessitate a revision to the global nitrogen cycle. ..
  25. Rigottier Gois L. Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis. ISME J. 2013;7:1256-61 pubmed publisher
    The healthy intestine is characterized by a low level of oxygen and by the presence of large bacterial communities of obligate anaerobes...
  26. Hasni I, Hamdani S, Carpentier R. Destabilization of the oxygen evolving complex of photosystem II by Al3+. Photochem Photobiol. 2013;89:1135-42 pubmed publisher
    ..A combination of oxygen evolution, chlorophyll fluorescence induction (FI) and decay and thermoluminescence measurements have been used to ..
  27. Glöckner C, Kern J, Broser M, Zouni A, Yachandra V, Yano J. Structural changes of the oxygen-evolving complex in photosystem II during the catalytic cycle. J Biol Chem. 2013;288:22607-20 pubmed publisher
    The oxygen-evolving complex (OEC) in the membrane-bound protein complex photosystem II (PSII) catalyzes the water oxidation reaction that takes place in oxygenic photosynthetic organisms...
  28. Lim H, Lim H, Park K, Seo D, Gwon H, Hong J, et al. Toward a lithium-"air" battery: the effect of CO2 on the chemistry of a lithium-oxygen cell. J Am Chem Soc. 2013;135:9733-42 pubmed publisher
    Lithium-oxygen chemistry offers the highest energy density for a rechargeable system as a "lithium-air battery"...
  29. Aboulnaga E, Pinkenburg O, Schiffels J, El Refai A, Buckel W, Selmer T. Effect of an oxygen-tolerant bifurcating butyryl coenzyme A dehydrogenase/electron-transferring flavoprotein complex from Clostridium difficile on butyrate production in Escherichia coli. J Bacteriol. 2013;195:3704-13 pubmed publisher
    ..The butyryl-CoA dehydrogenase from C. difficile is oxygen stable and apparently uses oxygen as a co-oxidant of NADH in the presence of air...
  30. Ganesh S, Parris D, DeLong E, Stewart F. Metagenomic analysis of size-fractionated picoplankton in a marine oxygen minimum zone. ISME J. 2014;8:187-211 pubmed publisher
    Marine oxygen minimum zones (OMZs) support diverse microbial communities with roles in major elemental cycles...
  31. Huang Y, Zhang X, Ma Z, Li W, Zhou Y, Zhou J, et al. Size, separation, structural order, and mass density of molecules packing in water and ice. Sci Rep. 2013;3:3005 pubmed publisher
    ..regions consisting molecules with fewer than four neighbors and, iii) repulsion between electron pairs on adjacent oxygen atoms dictates the cooperative relaxation of the segmented O:H-O bond, which is responsible for the performance of ..
  32. Zhao Z, Zhang J, Yuan Y, Lv H, Tian Y, Wu D, et al. In-situ formation of cobalt-phosphate oxygen-evolving complex-anchored reduced graphene oxide nanosheets for oxygen reduction reaction. Sci Rep. 2013;3:2263 pubmed publisher
    b>Oxygen conversion process between O? and H?O by means of electrochemistry or photochemistry has lately received a great deal of attention...
  33. Liang J, Du X, Gibson C, Du X, Qiao S. N-doped graphene natively grown on hierarchical ordered porous carbon for enhanced oxygen reduction. Adv Mater. 2013;25:6226-31 pubmed publisher
    ..The outstanding structural properties of the resultant material render it an excellent metal-free catalyst for electrochemical oxygen reduction.
  34. Louvaris Z, Kortianou E, Spetsioti S, Vasilopoulou M, Nasis I, Asimakos A, et al. Intensity of daily physical activity is associated with central hemodynamic and leg muscle oxygen availability in COPD. J Appl Physiol (1985). 2013;115:794-802 pubmed publisher
    ..There is limited evidence whether central hemodynamic, oxygen transport, and peripheral muscle oxygenation capacities also contribute to reduced daily physical activity...
  35. Bressan S, Balzani M, Krauss B, Pettenazzo A, Zanconato S, Baraldi E. High-flow nasal cannula oxygen for bronchiolitis in a pediatric ward: a pilot study. Eur J Pediatr. 2013;172:1649-56 pubmed publisher
    ..The aim of this study was to evaluate the feasibility of HFNC oxygen therapy in infants hospitalized in a pediatric ward for moderate-severe bronchiolitis and to assess the changes in ..
  36. Dawson J, Saraswat A, Simionato L, Thio M, Kamlin C, Owen L, et al. Comparison of heart rate and oxygen saturation measurements from Masimo and Nellcor pulse oximeters in newly born term infants. Acta Paediatr. 2013;102:955-60 pubmed publisher
    ..We also compared peripheral oxygen saturation (SpO2 ) measurements between Nellcor and Masimo oximeters.
  37. Lim K, Wheeler K, Gale T, Jackson H, Kihlstrand J, Sand C, et al. Oxygen saturation targeting in preterm infants receiving continuous positive airway pressure. J Pediatr. 2014;164:730-736.e1 pubmed publisher
    The precision of oxygen saturation (SpO2) targeting in preterm infants on continuous positive airway pressure (CPAP) is incompletely characterized...
  38. Maier P, Zemoura K, Acu a M, Y venes G, Zeilhofer H, Benke D. Ischemia-like oxygen and glucose deprivation mediates down-regulation of cell surface ?-aminobutyric acidB receptors via the endoplasmic reticulum (ER) stress-induced transcription factor CCAAT/enhancer-binding protein (C/EBP)-homologous protein (CH. J Biol Chem. 2014;289:12896-907 pubmed publisher
    ..stress in cultured cortical neurons by sustained Ca(2+) release from intracellular stores or by a brief episode of oxygen and glucose deprivation (in vitro model of cerebral ischemia), we observed an increased expression of CHOP ..
  39. Filas B, Shui Y, Beebe D. Computational model for oxygen transport and consumption in human vitreous. Invest Ophthalmol Vis Sci. 2013;54:6549-59 pubmed publisher
    Previous studies that measured liquefaction and oxygen content in human vitreous suggested that exposure of the lens to excess oxygen causes nuclear cataracts...
  40. Canfield D, Ngombi Pemba L, Hammarlund E, Bengtson S, Chaussidon M, Gauthier Lafaye F, et al. Oxygen dynamics in the aftermath of the Great Oxidation of Earth's atmosphere. Proc Natl Acad Sci U S A. 2013;110:16736-41 pubmed publisher
    The oxygen content of Earth's atmosphere has varied greatly through time, progressing from exceptionally low levels before about 2.3 billion years ago, to much higher levels afterward...
  41. de Pablo Y, Nilsson M, Pekna M, Pekny M. Intermediate filaments are important for astrocyte response to oxidative stress induced by oxygen-glucose deprivation and reperfusion. Histochem Cell Biol. 2013;140:81-91 pubmed publisher
    ..in J Cereb Blood Flow Metab 28(3):468-481, 2008). Here, we attempted to analyze the underlying mechanisms using oxygen-glucose deprivation (OGD), an in vitro ischemia model, examining a potential link between astrocyte intermediate ..
  42. Jeon I, Choi H, Choi M, Seo J, Jung S, Kim M, et al. Facile, scalable synthesis of edge-halogenated graphene nanoplatelets as efficient metal-free eletrocatalysts for oxygen reduction reaction. Sci Rep. 2013;3:1810 pubmed publisher
    ..Furthermore, XGnPs showed remarkable electrocatalytic activities toward oxygen reduction reaction (ORR) with a high selectivity, good tolerance to methanol crossover/CO poisoning effects, and ..
  43. Sjoberg F, Singer M. The medical use of oxygen: a time for critical reappraisal. J Intern Med. 2013;274:505-28 pubmed publisher
    b>Oxygen treatment has been a cornerstone of acute medical care for numerous pathological states. Initially, this was supported by the assumed need to avoid hypoxaemia and tissue hypoxia...
  44. Schunck H, Lavik G, Desai D, Großkopf T, Kalvelage T, Löscher C, et al. Giant hydrogen sulfide plume in the oxygen minimum zone off Peru supports chemolithoautotrophy. PLoS ONE. 2013;8:e68661 pubmed publisher
    ..Subsequent heterotrophic decomposition of the produced biomass increases the oxygen-depletion at intermediate water depths, which can result in the formation of oxygen minimum zones (OMZ)...
  45. Cerbo R, Maragliano R, Pozzi M, Strocchio L, Mostert M, Manzoni P, et al. Global perfusion assessment and tissue oxygen saturation in preterm infants: where are we?. Early Hum Dev. 2013;89 Suppl 1:S44-6 pubmed publisher
    ..examined, particularly the "two site NIRS" use in preterm infants, to evaluate how regional splanchnic oxygen saturation changes, both in physiological events, such as enteral feeding and in hemodynamic disorders, that occur ..
  46. Macaodha D, O Conghaile P, Egan B, Kavanagh P, Leech D. Membraneless glucose/oxygen enzymatic fuel cells using redox hydrogel films containing carbon nanotubes. Chemphyschem. 2013;14:2302-7 pubmed publisher
    ..5 mA cm(-2) for oxygen reduction at an applied potential of 0 V versus Ag/AgCl...
  47. Yamamoto S, Suda M, Niimi S, Inui M, Yukawa H. Strain optimization for efficient isobutanol production using Corynebacterium glutamicum under oxygen deprivation. Biotechnol Bioeng. 2013;110:2938-48 pubmed publisher
    ..one of the more isobutanol-tolerant industrial microorganisms, exhibits unprecedented productivity under oxygen deprivation, potentially allowing for high productivity of such toxic chemicals as isobutanol...
  48. Cordeiro R. Reactive oxygen species at phospholipid bilayers: distribution, mobility and permeation. Biochim Biophys Acta. 2014;1838:438-44 pubmed publisher
    Reactive oxygen species (ROS) are involved in biochemical processes such as redox signaling, aging, carcinogenesis and neurodegeneration...
  49. Beck D, Martin J, Casey D, Braith R. Exercise training reduces peripheral arterial stiffness and myocardial oxygen demand in young prehypertensive subjects. Am J Hypertens. 2013;26:1093-102 pubmed publisher
    ..Large artery stiffness is a major risk factor for the development of hypertension and cardiovascular disease. Persistent prehypertension accelerates the progression of arterial stiffness...
  50. Cabrales P, Intaglietta M. Blood substitutes: evolution from noncarrying to oxygen- and gas-carrying fluids. ASAIO J. 2013;59:337-54 pubmed publisher
    The development of oxygen (O2)-carrying blood substitutes has evolved from the goal of replicating blood O2 transport properties to that of preserving microvascular and organ function, reducing the inherent or potential toxicity of the ..
  51. Pita M, Gutiérrez Sánchez C, Toscano M, Shleev S, De Lacey A. Oxygen biosensor based on bilirubin oxidase immobilized on a nanostructured gold electrode. Bioelectrochemistry. 2013;94:69-74 pubmed publisher
    ..The nanostructured bioelectrodes were tested as mediator-less biosensors for oxygen in a buffer that mimics the content and the composition of human physiological fluids...
  52. Kang D, Dai J, Sun H, Hou Y, Yuan J. Quantum simulation of thermally-driven phase transition and oxygen K-edge x-ray absorption of high-pressure ice. Sci Rep. 2013;3:3272 pubmed publisher
    ..Here we investigated the temperature-induced phase transition and oxygen K-edge x-ray absorption spectra of ice VII, VIII and X using ab initio path-integral molecular dynamics ..
  53. Dymkowska D, Drabarek B, Podszywałow Bartnicka P, Szczepanowska J, Zabłocki K. Hyperglycaemia modifies energy metabolism and reactive oxygen species formation in endothelial cells in vitro. Arch Biochem Biophys. 2014;542:7-13 pubmed publisher
    There is significant evidence for an involvement of reactive oxygen species (ROS) in the pathogenesis of diabetic vascular complications through many metabolic and structural derangements...
  54. Sperling E, Frieder C, Raman A, Girguis P, Levin L, Knoll A. Oxygen, ecology, and the Cambrian radiation of animals. Proc Natl Acad Sci U S A. 2013;110:13446-51 pubmed publisher
    ..Using modern oxygen minimum zones as an analog for Proterozoic oceans, we explore the effect of low oxygen levels on the feeding ..
  55. Wang Y, Zhang F, Chiba S. Oxidative radical skeletal rearrangement induced by molecular oxygen: synthesis of quinazolinones. Org Lett. 2013;15:2842-5 pubmed publisher
    ..Oxidative skeletal rearrangement of 5-aryl-4,5-dihydro-1,2,4-oxadiazoles into quinazolinones is induced by molecular oxygen (under a dry air atmosphere) that likely proceeds via transient iminyl radical species...
  56. Zhu S, Ge J, Wang Y, Qi F, Ma T, Wang M, et al. A synthetic oxygen carrier-olfactory ensheathing cell composition system for the promotion of sciatic nerve regeneration. Biomaterials. 2014;35:1450-61 pubmed publisher
    ..However, low oxygen status has been found within nerve scaffolds after their implantation in vivo, which has been shown to result in ..
  57. Forster H, Haouzi P, Dempsey J. Control of breathing during exercise. Compr Physiol. 2012;2:743-77 pubmed publisher
    ..However, there is no compelling evidence to accept this concept as an indisputable fact...
  58. Jain V, Buckley E, Licht D, Lynch J, Schwab P, Naim M, et al. Cerebral oxygen metabolism in neonates with congenital heart disease quantified by MRI and optics. J Cereb Blood Flow Metab. 2014;34:380-8 pubmed publisher
    ..DOS), diffuse correlation spectroscopy (DCS)), were employed to quantify cerebral blood flow (CBF) and oxygen metabolism (CMRO(2)) of 32 anesthetized CHD neonates at rest and during hypercapnia...
  59. Kim S, Ståhlberg J, Sandgren M, Paton R, Beckham G. Quantum mechanical calculations suggest that lytic polysaccharide monooxygenases use a copper-oxyl, oxygen-rebound mechanism. Proc Natl Acad Sci U S A. 2014;111:149-54 pubmed publisher
    ..To date, several features of copper binding to LPMOs have been elucidated, but the identity of the reactive oxygen species and the key steps in the oxidative mechanism have not been elucidated...
  60. Sousa P, Videira M, Melo A. The formate:oxygen oxidoreductase supercomplex of Escherichia coli aerobic respiratory chain. FEBS Lett. 2013;587:2559-64 pubmed publisher
    The Escherichia coli formate:oxygen oxidoreductase supercomplex (FdOx) was investigated with respect to function and composition...
  61. Vavilala D, O Bryhim B, Ponnaluri V, White R, Radel J, Symons R, et al. Honokiol inhibits pathological retinal neovascularization in oxygen-induced retinopathy mouse model. Biochem Biophys Res Commun. 2013;438:697-702 pubmed publisher
    ..we show for the first time that daily intraperitoneal injection of honokiol starting at postnatal day (P) 12 in an oxygen-induced retinopathy (OIR) mouse model significantly reduced retinal neovascularization at P17...
  62. Schriver M, Regan W, Gannett W, Zaniewski A, Crommie M, Zettl A. Graphene as a long-term metal oxidation barrier: worse than nothing. ACS Nano. 2013;7:5763-8 pubmed publisher
    ..In addition to informing any future work on graphene as a protective coating, the results presented here have implications for graphene's performance in a wide range of applications. ..
  63. Astorino T, Schubert M, Palumbo E, Stirling D, McMillan D, Cooper C, et al. Magnitude and time course of changes in maximal oxygen uptake in response to distinct regimens of chronic interval training in sedentary women. Eur J Appl Physiol. 2013;113:2361-9 pubmed publisher
    This study aimed to compare changes in maximal oxygen uptake (VO2max) in response to two regimens of chronic interval training.
  64. Campbell E, Bruyninckx W, Kelly C, Glover L, McNamee E, Bowers B, et al. Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation. Immunity. 2014;40:66-77 pubmed publisher
    ..In conclusion, transcriptional imprinting by infiltrating neutrophils modulates the host response to inflammation, via localized O2 depletion, resulting in microenvironmental hypoxia and effective inflammatory resolution. ..
  65. Quesne M, Latifi R, Gonzalez Ovalle L, Kumar D, de Visser S. Quantum mechanics/molecular mechanics study on the oxygen binding and substrate hydroxylation step in AlkB repair enzymes. Chemistry. 2014;20:435-46 pubmed publisher
    ..Firstly, the initial modelling identified the oxygen binding site of the enzyme...
  66. Rummer J, McKenzie D, Innocenti A, Supuran C, Brauner C. Root effect hemoglobin may have evolved to enhance general tissue oxygen delivery. Science. 2013;340:1327-9 pubmed publisher
    ..report that when rainbow trout are exposed to elevated water carbon dioxide (CO2), red muscle partial pressure of oxygen (PO2) increases by 65%--evidence that Root hemoglobins enhance general tissue O2 delivery during acidotic stress...
  67. Lyons T, Reinhard C, Planavsky N. The rise of oxygen in Earth's early ocean and atmosphere. Nature. 2014;506:307-15 pubmed publisher
    ..But for the atmosphere of roughly two-and-half billion years ago, interest centres on a different gas: free oxygen (O2) spawned by early biological production...
  68. Siegbahn P. Substrate water exchange for the oxygen evolving complex in PSII in the S1, S2, and S3 states. J Am Chem Soc. 2013;135:9442-9 pubmed publisher
    Detailed mechanisms for substrate water exchange in the oxygen evolving complex in photosystem II have been determined with DFT methods for large models...
  69. Kusuma S, Peijnenburg E, Patel P, Gerecht S. Low oxygen tension enhances endothelial fate of human pluripotent stem cells. Arterioscler Thromb Vasc Biol. 2014;34:913-20 pubmed publisher
    A critical regulator of the developing or regenerating vasculature is low oxygen tension...
  70. Cao R, Thapa R, Kim H, Xu X, Gyu Kim M, Li Q, et al. Promotion of oxygen reduction by a bio-inspired tethered iron phthalocyanine carbon nanotube-based catalyst. Nat Commun. 2013;4:2076 pubmed publisher
    Electrocatalysts for oxygen reduction are a critical component that may dramatically enhance the performance of fuel cells and metal-air batteries, which may provide the power for future electric vehicles...
  71. Graff B, Szyndler A, Czechowicz K, Kucharska W, Graff G, Boutouyrie P, et al. Relationship between heart rate variability, blood pressure and arterial wall properties during air and oxygen breathing in healthy subjects. Auton Neurosci. 2013;178:60-6 pubmed publisher
    ..Several factors are considered including degeneration of endothelium-derived nitric oxide by reactive oxygen species, the impact of oxygen-free radicals on tissues and alterations of autonomic nervous system function...
  72. Mairbäurl H, Weber R. Oxygen transport by hemoglobin. Compr Physiol. 2012;2:1463-89 pubmed publisher
    Hemoglobin (Hb) constitutes a vital link between ambient O2 availability and aerobic metabolism by transporting oxygen (O2) from the respiratory surfaces of the lungs or gills to the O2-consuming tissues...
  73. Vassiliev S, Zaraiskaya T, Bruce D. Molecular dynamics simulations reveal highly permeable oxygen exit channels shared with water uptake channels in photosystem II. Biochim Biophys Acta. 2013;1827:1148-55 pubmed publisher
    ..Water delivery and oxygen removal from the oxygen evolving complex (OEC), buried deep within PSII, are critical requirements to facilitate ..
  74. Kumar P, Prabhakar N. Peripheral chemoreceptors: function and plasticity of the carotid body. Compr Physiol. 2012;2:141-219 pubmed publisher
    ..The mechanisms and consequences of carotid body plasticity in health and disease are discussed in the final sections of this article...
  75. Wang X, Wang G, Kunte M, Shinde V, Gorbatyuk M. Modulation of angiogenesis by genetic manipulation of ATF4 in mouse model of oxygen-induced retinopathy [corrected]. Invest Ophthalmol Vis Sci. 2013;54:5995-6002 pubmed publisher
    ..Therefore, the objective of this study was to determine whether ATF4 deficiency could reduce neovascularization in mice with oxygen-induced retinopathy (OIR).
  76. Sun S, Li Z, Chen S. A dominant homolytic O-Cl bond cleavage with low-spin triplet-state Fe(IV)=O formed is revealed in the mechanism of heme-dependent chlorite dismutase. Dalton Trans. 2014;43:973-81 pubmed publisher
  77. Wanek J, Teng P, Blair N, Shahidi M. Inner retinal oxygen delivery and metabolism in streptozotocin diabetic rats. Invest Ophthalmol Vis Sci. 2014;55:1588-93 pubmed publisher
    The purpose of the study is to report global measurements of inner retinal oxygen delivery (DO2_IR) and oxygen metabolism (MO2_IR) in streptozotocin (STZ) diabetic rats.
  78. Huang Z, Fujiwara K, Minamide R, Hasegawa K, Yoshikawa K. Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner. J Neurosci. 2013;33:10362-73 pubmed publisher
    ..These results suggest that oxygen tension regulates the necdin protein level in NSCs through HIF-2?-mediated proteasomal degradation to modulate ..
  79. Pérez Navarro M, Ames W, Nilsson H, Lohmiller T, Pantazis D, Rapatskiy L, et al. Ammonia binding to the oxygen-evolving complex of photosystem II identifies the solvent-exchangeable oxygen bridge (?-oxo) of the manganese tetramer. Proc Natl Acad Sci U S A. 2013;110:15561-6 pubmed publisher
    The assignment of the two substrate water sites of the tetra-manganese penta-oxygen calcium (Mn4O5Ca) cluster of photosystem II is essential for the elucidation of the mechanism of biological O-O bond formation and the subsequent design ..
  80. Flores C, Moreno S, Espín G, Pena C, Galindo E. Expression of alginases and alginate polymerase genes in response to oxygen, and their relationship with the alginate molecular weight in Azotobacter vinelandii. Enzyme Microb Technol. 2013;53:85-91 pubmed publisher
    ..polymerization and depolymerization, as well as the alginase activity (extracellular and intracellular) under oxygen-limited and non oxygen-limited conditions in cultures of A. vinelandii, was studied...
  81. Howard M, Asmis R, Evans K, Mustoe T. Oxygen and wound care: a review of current therapeutic modalities and future direction. Wound Repair Regen. 2013;21:503-11 pubmed publisher
    While the importance of oxygen to the wound healing process is well accepted, research and technological advances continue in this field and efforts are ongoing to further utilize oxygen as a therapeutic modality...
  82. Blanco Suarez E, Hanley J. Distinct subunit-specific ?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking mechanisms in cultured cortical and hippocampal neurons in response to oxygen and glucose deprivation. J Biol Chem. 2014;289:4644-51 pubmed publisher
    Brain ischemia occurs when the blood supply to the brain is interrupted, leading to oxygen and glucose deprivation (OGD). This triggers a cascade of events causing a synaptic accumulation of glutamate...
  83. Karunasinghe R, Lipski J. Oxygen and glucose deprivation (OGD)-induced spreading depression in the Substantia Nigra. Brain Res. 2013;1527:209-21 pubmed publisher
    ..Transverse brain slices (250 ?m; P21-23 rats) containing the SN were subject to oxygen and glucose deprivation (OGD) tests, modeling brain ischemia. SD developed in lateral aspects of the SN within 3...
  84. Anastasopoulos A, Davies J, Hannah L, Hayden B, Lee C, Milhano C, et al. The particle size dependence of the oxygen reduction reaction for carbon-supported platinum and palladium. ChemSusChem. 2013;6:1973-82 pubmed publisher
    ..5-5.5 nm over 100 electrodes of an electrochemical screening chip, allowing the oxygen reduction reaction (ORR) activity of the catalysts to be determined simultaneously...
  85. Diers A, Vayalil P, Oliva C, Griguer C, Darley Usmar V, Hurst D, et al. Mitochondrial bioenergetics of metastatic breast cancer cells in response to dynamic changes in oxygen tension: effects of HIF-1?. PLoS ONE. 2013;8:e68348 pubmed publisher
    Solid tumors are characterized by regions of low oxygen tension (OT), which play a central role in tumor progression and resistance to therapy...
  86. Sun X, Song P, Zhang Y, Liu C, Xu W, Xing W. A class of high performance metal-free oxygen reduction electrocatalysts based on cheap carbon blacks. Sci Rep. 2013;3:2505 pubmed publisher
    ..of practical industrial development of fuel cells, cheap, sustainable and high performance electrocatalysts for oxygen reduction reactions (ORR) which rival those based on platinum (Pt) and other rare materials are highly desirable...
  87. Hartnett M, Lane R. Effects of oxygen on the development and severity of retinopathy of prematurity. J AAPOS. 2013;17:229-34 pubmed publisher
    ..of prematurity (ROP) first manifested as retrolental fibroplasia, the technology to monitor or regulate oxygen did not exist, and a fundus examination of preterm infants was not routinely performed...
  88. Spencer J, Ferraro F, Roussakis E, Klein A, Wu J, Runnels J, et al. Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature. 2014;508:269-73 pubmed publisher
    ..Low oxygen tension (hypoxia) is commonly thought to be a shared niche characteristic in maintaining quiescence in multiple ..
  89. Sun Q, Wang B, Miyagi M, Hess D, Stamler J. Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor/Ca2+ release channel (RyR1): sites and nature of oxidative modification. J Biol Chem. 2013;288:22961-71 pubmed publisher
    ..S-Oxidation of RyR1 is coupled to muscle oxygen tension (pO2) through O2-dependent production of hydrogen peroxide by SR-resident NADPH oxidase 4...