plasma

Summary

Summary: The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION.

Top Publications

  1. Oliveira C, Santos Filho N, Menaldo D, Boldrini França J, Giglio J, Calderon L, et al. Structural and functional characterization of a ?-type phospholipase A2 inhibitor from bothrops jararacussu snake plasma. Curr Top Med Chem. 2011;11:2509-19 pubmed
    ..characterization of a ?-type phospholipase A2 inhibitor (PLI) from Bothrops jararacussu snake plasma, named ?BjussuMIP...
  2. Clement C, Aphkhazava D, Nieves E, Callaway M, Olszewski W, Rotzschke O, et al. Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS-PAGE coupled with nanoLC-ESI-MS/MS bottom-up proteomics. J Proteomics. 2013;78:172-87 pubmed publisher
    ..a proteomic approach was used to define the protein content of matched samples of afferent prenodal lymph and plasma derived from healthy volunteers...
  3. Barker G, Lim R, Georgiou H, Lappas M. Omentin-1 is decreased in maternal plasma, placenta and adipose tissue of women with pre-existing obesity. PLoS ONE. 2012;7:e42943 pubmed publisher
    ..obesity and gestational diabetes mellitus (GDM) on (i) the circulating levels of omentin-1 in cord and maternal plasma, and (ii) gene expression and release of omentin-1 from human placenta and adipose tissue...
  4. Creaney J, Yeoman D, Musk A, de Klerk N, Skates S, Robinson B. Plasma versus serum levels of osteopontin and mesothelin in patients with malignant mesothelioma--which is best?. Lung Cancer. 2011;74:55-60 pubmed publisher
    ..As there is some concern about the sensitivity of osteopontin in serum versus plasma, we compared them in the same patient population to mesothelin...
  5. Balderas C, Rupérez F, Ibáñez E, Señorans J, Guerrero Fernández J, Casado I, et al. Plasma and urine metabolic fingerprinting of type 1 diabetic children. Electrophoresis. 2013;34:2882-90 pubmed publisher
    ..The objective of the present study was to investigate the alterations in plasma (by LC-MS) and urine (CE-MS) of type 1 diabetic children that were under insulin treatment and good glycemic ..
  6. Vaquerizo V, Plasencia M, Arribas I, Seijas R, Padilla S, Orive G, et al. Comparison of intra-articular injections of plasma rich in growth factors (PRGF-Endoret) versus Durolane hyaluronic acid in the treatment of patients with symptomatic osteoarthritis: a randomized controlled trial. Arthroscopy. 2013;29:1635-43 pubmed publisher
  7. Cheng H, Yi H, Kim Y, Kroh E, Chien J, Eaton K, et al. Plasma processing conditions substantially influence circulating microRNA biomarker levels. PLoS ONE. 2013;8:e64795 pubmed publisher
    ..Our previous work showed that the majority of plasma miRNAs are likely blood cell-derived...
  8. Sharpe J, Weinberg J, Magnotti L, Fabian T, Croce M. Does plasma transfusion portend pulmonary dysfunction? A tale of two ratios. J Trauma Acute Care Surg. 2013;75:32-6; discussion 36 pubmed publisher
    ..in the setting of massive hemorrhage is potential lung injury from the transfusion of relatively more plasma-rich components...
  9. Gonzalez R, Sjunnesson Y. Effect of blood plasma collected after adrenocorticotropic hormone administration during the preovulatory period in the sow on oocyte in vitro maturation. Theriogenology. 2013;80:673-83 pubmed publisher
    ..Here, the effect of simulated stress by media supplementation with blood plasma from sows after adrenocorticotropic hormone (ACTH) administration during the preovulatory period was assessed...

More Information

Publications74

  1. Laoprasopwattana K, Tangcheewawatthanakul C, Tunyapanit W, Sangthong R. Is zinc concentration in toxic phase plasma related to dengue severity and level of transaminases?. PLoS Negl Trop Dis. 2013;7:e2287 pubmed publisher
    To determine the relationship between plasma zinc values and the severity of dengue viral infection (DVI) and DVI-caused hepatitis.
  2. Imam A, Jin G, Duggan M, Sillesen M, Hwabejire J, Jepsen C, et al. Synergistic effects of fresh frozen plasma and valproic acid treatment in a combined model of traumatic brain injury and hemorrhagic shock. Surgery. 2013;154:388-96 pubmed publisher
    ..Previously, we showed that early administration of fresh frozen plasma (FFP) decreased the size of the brain lesion and associated swelling in a swine model of combined TBI+HS...
  3. Zhao Y, Zheng Z, Jin S, Liang H. Effects of plasma collected 48 hours after transient limb ischemia on blood pressure recovery in homogenic rats after myocardial ischemia reperfusion in vivo. Chin Med J (Engl). 2013;126:2894-9 pubmed
    Whether plasma can transfer the protective effect(s) of remote ischemic preconditioning (RIPC) between animals remains unresolved...
  4. Cotoi O, Manjer J, Hedblad B, Engstrom G, Melander O, Schiopu A. Plasma procalcitonin is associated with all-cause and cancer mortality in apparently healthy men: a prospective population-based study. BMC Med. 2013;11:180 pubmed publisher
    ..Our aim was to assess the relationship between plasma PCT and the risk of all-cause and cause-specific mortality in apparently healthy individuals with no previous ..
  5. Tian H, Bai J, An Z, Chen Y, Zhang R, He J, et al. Plasma metabolome analysis by integrated ionization rapid-resolution liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2013;27:2071-80 pubmed publisher
    Acquiring global information on plasma-endogenous metabolites challenges metabolomics...
  6. Martinez Ocaña J, Olivo Díaz A, Salazar Dominguez T, Reyes Gordillo J, Tapia Aquino C, Martinez Hernandez F, et al. Plasma cytokine levels and cytokine gene polymorphisms in Mexican patients during the influenza pandemic A(H1N1)pdm09. J Clin Virol. 2013;58:108-13 pubmed publisher
    ..Polymorphisms in interleukin genes have previously been associated with susceptibility to infectious diseases due to their influence on cytokine production...
  7. Ding Y, Yang H, Feng J, Qiu Y, Li D, Zeng Y. Human umbilical cord-derived MSC culture: the replacement of animal sera with human cord blood plasma. In Vitro Cell Dev Biol Anim. 2013;49:771-7 pubmed publisher
    ..However, it is not clear whether human umbilical cord blood plasma (UCBP), as the surplusage of umbilical cord blood mesenchymal stem cell extraction, could be used...
  8. Quackenbush J, Cassidy P, Pfeffer L, Boucher K, Hawkes J, Pfeffer S, et al. Isolation of circulating microRNAs from microvesicles found in human plasma. Methods Mol Biol. 2014;1102:641-53 pubmed publisher
    ..This protocol allows for isolation all microvesicles, regardless of their origin, and provides a convenient method for identifying potential cancer-specific biomarkers from biological fluids including serum and plasma.
  9. Liu C, Mauk M, Gross R, Bushman F, Edelstein P, Collman R, et al. Membrane-based, sedimentation-assisted plasma separator for point-of-care applications. Anal Chem. 2013;85:10463-70 pubmed publisher
    Often, high-sensitivity, point-of-care (POC) clinical tests, such as HIV viral load, require large volumes of plasma. Although centrifuges are ubiquitously used in clinical laboratories to separate plasma from whole blood, centrifugation ..
  10. Kalra H, Adda C, Liem M, Ang C, Mechler A, Simpson R, et al. Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma. Proteomics. 2013;13:3354-64 pubmed publisher
    ..into practice, the stability of exosomes needs to be assessed and exosome isolation protocols from blood plasma need to be optimized...
  11. Petravic J, Vanderford T, Silvestri G, Davenport M. Estimating the contribution of the gut to plasma viral load in early SIV infection. Retrovirology. 2013;10:105 pubmed publisher
    ..Here we aimed to estimate the contribution of the gut to the total virus observed in plasma, by comparing the frequency of different viral mutants in plasma and gut in SIV infection.
  12. Gandhi M, Mwesigwa J, Aweeka F, Plenty A, Charlebois E, Ruel T, et al. Hair and plasma data show that lopinavir, ritonavir, and efavirenz all transfer from mother to infant in utero, but only efavirenz transfers via breastfeeding. J Acquir Immune Defic Syndr. 2013;63:578-84 pubmed publisher
    ..Antiretroviral levels in plasma, cord blood, and breastmilk reflect exposure over short intervals...
  13. Graham S, Rajwans N, Jaoko W, Estambale B, McClelland R, Overbaugh J, et al. Endothelial activation biomarkers increase after HIV-1 acquisition: plasma vascular cell adhesion molecule-1 predicts disease progression. AIDS. 2013;27:1803-13 pubmed publisher
    ..We aimed to determine whether endothelial activation biomarkers increase after HIV-1 acquisition, and whether biomarker levels measured in chronic infection would predict disease progression and death in HIV-1 seroconverters...
  14. Culot M, Fabulas da Costa A, Sevin E, Szorath E, Martinsson S, Renftel M, et al. A simple method for assessing free brain/free plasma ratios using an in vitro model of the blood brain barrier. PLoS ONE. 2013;8:e80634 pubmed publisher
    ..has been to use in vitro BBB models to optimize rate of drug delivery to the CNS, whereas total in vivo brain/plasma ratios have been used for optimizing extent...
  15. Liu X, Lu Y, Zhu G, Lei Y, Zheng L, Qin H, et al. The diagnostic accuracy of pleural effusion and plasma samples versus tumour tissue for detection of EGFR mutation in patients with advanced non-small cell lung cancer: comparison of methodologies. J Clin Pathol. 2013;66:1065-9 pubmed publisher
    To evaluate the suitability of malignant pleural effusion (MPE) and plasma as surrogate samples for epidermal growth factor receptor (EGFR) mutation detection, and compare three different detection methods.
  16. Delarue S, Didier E, Damond F, Ponscarme D, Brengle Pesce K, Resche Rigon M, et al. Highly sensitive plasma RNA quantification by real-time PCR in HIV-2 group A and group B infection. J Clin Virol. 2013;58:461-7 pubmed publisher
    b>Plasma HIV-2 viral load has been reported as predictive of AIDS in HIV-2 infected patient but the lack of sensitivity of the current HIV2 viral load assay is a limitation for the monitoring of the HIV-2-infected patients.
  17. Mouinga Ondeme A, Mabika Mabika A, Alalade P, Mongo A, Sica J, Liegeois F, et al. Significant impact of non-B HIV-1 variants genetic diversity in Gabon on plasma HIV-1 RNA quantitation. J Med Virol. 2014;86:52-7 pubmed publisher
    ..A total of 137 plasma specimens were assessed for HIV-1 RNA using the Abbott RealTime HIV-1® and Nuclisens HIV-1 EasyQ® version 2...
  18. Chan K, Jiang P, Chan C, Sun K, Wong J, Hui E, et al. Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing. Proc Natl Acad Sci U S A. 2013;110:18761-8 pubmed publisher
    We explored the detection of genome-wide hypomethylation in plasma using shotgun massively parallel bisulfite sequencing as a marker for cancer...
  19. Imam A, Jin G, Sillesen M, Duggan M, Jepsen C, Hwabejire J, et al. Early treatment with lyophilized plasma protects the brain in a large animal model of combined traumatic brain injury and hemorrhagic shock. J Trauma Acute Care Surg. 2013;75:976-83 pubmed publisher
    ..We have previously shown that early administration of fresh frozen plasma (FFP) in a large animal model of TBI and HS reduces the size of the brain lesion as well as the associated edema...
  20. Rogowska Szadkowska D. Consequences of the commercialisation of plasma and blood in China. Przegl Epidemiol. 2011;65:515-9 pubmed
    ..In this review a history of HIV infections was presented showing that blood and blood products cannot be treated as commercial goods. ..
  21. Peace R, Campbell J, Polo J, Crenshaw J, Russell L, Moeser A. Spray-dried porcine plasma influences intestinal barrier function, inflammation, and diarrhea in weaned pigs. J Nutr. 2011;141:1312-7 pubmed publisher
    The objective of this study was to evaluate the effects of dietary inclusion levels of spray-dried porcine plasma (SDPP) on postweaning (PW) intestinal barrier function, mucosal inflammation, and clinical indices of gut health in pigs...
  22. Longo L, Nakayasu E, Gazos Lopes F, Vallejo M, Matsuo A, Almeida I, et al. Characterization of cell wall lipids from the pathogenic phase of Paracoccidioides brasiliensis cultivated in the presence or absence of human plasma. PLoS ONE. 2013;8:e63372 pubmed publisher
    ..brasiliensis grown in the presence and absence of human plasma. We compared the results from isolates Pb3 and Pb18, which represent different phylogenetic species that evoke ..
  23. Pandey S, Vyas G. Adverse effects of plasma transfusion. Transfusion. 2012;52 Suppl 1:65S-79S pubmed publisher
    b>Plasma utilization has increased over the past two decades, and there is a growing concern that many plasma transfusions are inappropriate...
  24. Blondal T, Jensby Nielsen S, Baker A, Andreasen D, Mouritzen P, Wrang Teilum M, et al. Assessing sample and miRNA profile quality in serum and plasma or other biofluids. Methods. 2013;59:S1-6 pubmed publisher
    ..The high relative stability of miRNA in common clinical tissues and biofluids (e.g. plasma, serum, urine, saliva, etc...
  25. Wirden M, Soulie C, Valantin M, Fourati S, Simon A, Lambert Niclot S, et al. Historical HIV-RNA resistance test results are more informative than proviral DNA genotyping in cases of suppressed or residual viraemia. J Antimicrob Chemother. 2011;66:709-12 pubmed publisher
    ..is often requested due to residual HIV viraemia or for treatment optimization, but may be unsuccessful if plasma RNA levels are too low or undetectable...
  26. Gilliss B, Looney M, Gropper M. Reducing noninfectious risks of blood transfusion. Anesthesiology. 2011;115:635-49 pubmed publisher
    ..and several controversial methods for prevention of noninfectious complications of transfusion are discussed, including universal leukoreduction of erythrocyte units, use of male-only plasma, and restriction of erythrocyte storage age.
  27. Grant R, Ansa Addo E, Stratton D, Antwi Baffour S, Jorfi S, Kholia S, et al. A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma. J Immunol Methods. 2011;371:143-51 pubmed publisher
    The methods of Plasma Membrane-derived Vesicle (PMV) isolation and quantification vary considerably in the literature and a new standard needs to be defined...
  28. Poon K, Lyng F, Knief P, Howe O, Meade A, Curtin J, et al. Quantitative reagent-free detection of fibrinogen levels in human blood plasma using Raman spectroscopy. Analyst. 2012;137:1807-14 pubmed publisher
    ..Raman spectroscopy was investigated for its ability to accurately quantify fibrinogen concentration in blood plasma. Samples collected from 34 patients were analysed by Raman spectroscopy and the resultant spectra were fitted with ..
  29. Chou M, Wu Y, Su C, Lee L, Burnouf T. Impact of solvent/detergent treatment of plasma on transfusion-relevant bacteria. Vox Sang. 2012;102:277-84 pubmed publisher
    A solvent/detergent (S/D) treatment in a medical device has been developed for pathogen reduction of plasma for transfusion...
  30. Kemal K, Ramirez C, Burger H, Foley B, Mayers D, Klimkait T, et al. Recombination between variants from genital tract and plasma: evolution of multidrug-resistant HIV type 1. AIDS Res Hum Retroviruses. 2012;28:1766-74 pubmed publisher
    ..variants in infected individuals, we studied recombination between single viral genomes from the genital tract and plasma of a woman initiating ART...
  31. Liegeois F, Boué V, Mouinga Ondeme A, Lékané D, Mongo D, Sica J, et al. Suitability of an open automated nucleic acid extractor for high-throughput plasma HIV-1 RNA quantitation in Gabon (Central Africa). J Virol Methods. 2012;179:269-71 pubmed publisher
    ..Since people living with HIV-1 are being treated with antiretrovirals in Gabon, this automated extraction technique represents an excellent technical method for high-throughput monitoring of HIV-1 RNA viral load...
  32. Khan I, Ravindran R, Krishnan V, Awan I, Rizvi S, Saqib M, et al. Plasma antibody profiles as diagnostic biomarkers for tuberculosis. Clin Vaccine Immunol. 2011;18:2148-53 pubmed publisher
    ..We have developed a multiplex panel of 28 M. tuberculosis antigen-coated microbeads. Plasma samples were obtained from over 300 pulmonary TB patients and healthy controls in a country where TB is endemic, ..
  33. Kim S, Sung J, Kang W, Ahn S, Kim D, Chin H, et al. Increased plasma osmolar gap is predictive of contrast-induced acute kidney injury. Tohoku J Exp Med. 2012;228:109-17 pubmed
    ..Hyperosmolarity and large amounts of contrast media are risk factors for CIAKI. However, there is no study on plasma osmolar gap as a predictor of CIAKI...
  34. Carlier M, Stove V, Roberts J, Van de Velde E, De Waele J, Verstraete A. Quantification of seven ?-lactam antibiotics and two ?-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method. Int J Antimicrob Agents. 2012;40:416-22 pubmed publisher
    There is an increasing interest in monitoring plasma concentrations of ?-lactam antibiotics...
  35. Blish C, McClelland R, Richardson B, Jaoko W, Mandaliya K, Baeten J, et al. Genital Inflammation Predicts HIV-1 Shedding Independent of Plasma Viral Load and Systemic Inflammation. J Acquir Immune Defic Syndr. 2012;61:436-40 pubmed publisher
    In women, genital HIV-1 RNA levels predict the risk of HIV-1 transmission independent of plasma viral load...
  36. Liu Y, Fang Z, Liu L, Yang S, Zhang L. Detection of Epstein-Barr virus DNA in serum or plasma for nasopharyngeal cancer: a meta-analysis. Genet Test Mol Biomarkers. 2011;15:495-502 pubmed publisher
    Studies have shown that the plasma or serum cell-free Epstein-Barr virus (EBV) DNA level might be a tumor marker for the diagnosis of nasopharyngeal carcinoma (NPC).
  37. Kim P, Kim Y, Koo I, Jung J, Kim G, Choi M, et al. Bacterial inactivation of wound infection in a human skin model by liquid-phase discharge plasma. PLoS ONE. 2011;6:e24104 pubmed publisher
    We investigate disinfection of a reconstructed human skin model contaminated with biofilm-formative Staphylococcus aureus employing plasma discharge in liquid.
  38. Gomes P, Carvalho A, Diogo I, Gonçalves F, Costa I, Cabanas J, et al. Comparison of the NucliSENS EasyQ HIV-1 v2.0 with Abbott m2000rt RealTime HIV-1 assay for plasma RNA quantitation in different HIV-1 subtypes. J Virol Methods. 2013;193:18-22 pubmed publisher
    Quantitation of HIV-1 RNA levels in plasma has significant prognostic value since high viral load concentrations in plasma are associated with a faster disease progression...
  39. Taschieri S, Del Fabbro M. Postextraction osteotome sinus floor elevation technique using plasma-rich growth factors. Implant Dent. 2011;20:418-24 pubmed publisher
    ..To evaluate a modified osteotome sinus floor elevation technique with immediate postextraction implant placement and the adjunct of a platelet-derived fibrin plug for the rehabilitation of maxillary premolar sites...
  40. Harenberg J, Marx S, Krämer R, Giese C, Weiss C. Determination of an international sensitivity index of thromboplastin reagents using a WHO thromboplastin as calibrator for plasma spiked with rivaroxaban. Blood Coagul Fibrinolysis. 2011;22:637-41 pubmed publisher
    ..reagents and coagulation analysers for determination of the anticoagulant effect of rivaroxaban in human plasma. Purity of rivaroxaban extracted from commercially available drug was confirmed by mass spectrometry, elemental ..
  41. Dunn W, Broadhurst D, Begley P, Zelena E, Francis McIntyre S, Anderson N, et al. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat Protoc. 2011;6:1060-83 pubmed publisher
    ..Protocols for serum- and plasma-based metabolic profiling applying gas chromatography-MS (GC-MS) and ultraperformance liquid chromatography-MS (..
  42. Warmuth M, Mad P, Wild C. Systematic review of the efficacy and safety of fibrinogen concentrate substitution in adults. Acta Anaesthesiol Scand. 2012;56:539-48 pubmed publisher
    A sufficient plasma level of fibrinogen is critical for the formation of a fibrin clot and haemostasis in both the perioperative setting and in massive haemorrhage...
  43. Park Y, Jones D, Ziegler T, Lee K, Kotha K, Yu T, et al. Metabolic effects of albumin therapy in acute lung injury measured by proton nuclear magnetic resonance spectroscopy of plasma: a pilot study. Crit Care Med. 2011;39:2308-13 pubmed publisher
    ..This pilot study evaluated plasma proton nuclear magnetic resonance spectroscopy as a means to monitor metabolism following albumin administration ..
  44. Barri T, Holmer Jensen J, Hermansen K, Dragsted L. Metabolic fingerprinting of high-fat plasma samples processed by centrifugation- and filtration-based protein precipitation delineates significant differences in metabolite information coverage. Anal Chim Acta. 2012;718:47-57 pubmed publisher
    ..Blood serum or plasma samples are often employed for metabolomics studies...
  45. White L, Friedman M, Nichols C, Menzin J, Hoesche J, Bergman G, et al. Factors associated with failure to correct the international normalised ratio following fresh frozen plasma administration among patients treated for warfarin-related major bleeding. An analysis of electronic health records. Thromb Haemost. 2012;107:662-72 pubmed publisher
    ..associated with failure to correct international normalised ratio (INR) in patients administered fresh frozen plasma (FFP) for warfarin-related major bleeding...
  46. Vardhanabhuti S, Acosta E, Ribaudo H, Severe P, Lalloo U, Kumarasamy N, et al. Clinical and genetic determinants of plasma nevirapine exposure following an intrapartum dose to prevent mother-to-child HIV transmission. J Infect Dis. 2013;208:662-71 pubmed publisher
    ..We characterized relationships between clinical parameters, human genetics, pharmacokinetics, and human immunodeficiency virus type 1 (HIV-1) drug resistance mutations in pregnant women following single-dose intrapartum nevirapine...
  47. Fox L, Taylor T, Pensulo P, Liomba A, Mpakiza A, Varela A, et al. Histidine-rich protein 2 plasma levels predict progression to cerebral malaria in Malawian children with Plasmodium falciparum infection. J Infect Dis. 2013;208:500-3 pubmed publisher
    ..The objective of this study was to determine if plasma concentrations of a malaria protein, HRP2 (histidine-rich protein 2) would serve this purpose...
  48. Johansson P, Sørensen A, Larsen C, Windeløv N, Stensballe J, Perner A, et al. Low hemorrhage-related mortality in trauma patients in a Level I trauma center employing transfusion packages and early thromboelastography-directed hemostatic resuscitation with plasma and platelets. Transfusion. 2013;53:3088-99 pubmed publisher
    ..Hemorrhage accounts for most preventable trauma deaths, but still the optimal strategy for hemostatic resuscitation remains debated...
  49. Tang H, Beer L, Speicher D. In-depth analysis of a plasma or serum proteome using a 4D protein profiling method. Methods Mol Biol. 2011;728:47-67 pubmed publisher
    Comprehensive proteomic analysis of human plasma or serum has been a major strategy used to identify biomarkers that serve as indicators of disease...
  50. Anitua E, Tejero R, Zalduendo M, Orive G. Plasma rich in growth factors promotes bone tissue regeneration by stimulating proliferation, migration, and autocrine secretion in primary human osteoblasts. J Periodontol. 2013;84:1180-90 pubmed publisher
    ..Osteoblasts are the main cells charged with the repair and regeneration of missing bone tissue. Plasma rich in growth factors (PRGF) allows delivery of a cocktail of proteins and growth factors that promote wound ..
  51. Samama M, Contant G, Spiro T, Perzborn E, Flem L, Guinet C, et al. Evaluation of the prothrombin time for measuring rivaroxaban plasma concentrations using calibrators and controls: results of a multicenter field trial. Clin Appl Thromb Hemost. 2012;18:150-8 pubmed publisher
    This study evaluated the prothrombin time (PT) assay for the measurement of plasma concentrations of rivaroxaban using calibrators and controls...
  52. Belderbos M, Levy O, Stalpers F, Kimpen J, Meyaard L, Bont L. Neonatal plasma polarizes TLR4-mediated cytokine responses towards low IL-12p70 and high IL-10 production via distinct factors. PLoS ONE. 2012;7:e33419 pubmed publisher
    ..Here, we demonstrate that neonatal plasma polarizes TLR4-mediated cytokine production...
  53. Varshney A, Rehan M, Subbarao N, Rabbani G, Khan R. Elimination of endogenous toxin, creatinine from blood plasma depends on albumin conformation: site specific uremic toxicity & impaired drug binding. PLoS ONE. 2011;6:e17230 pubmed publisher
    ..Alkalinization of normal plasma from pH 7.0 to 9...
  54. Liu Q, Zhao D, Chen X, Li Z, Li N, Han D, et al. Determination of corosolic acid, a natural potential anti-diabetes compound, in rat plasma by high-performance liquid chromatography-mass spectrometry and its application to pharmacokinetic and bioavailability studies. Planta Med. 2011;77:1707-11 pubmed publisher
    ..method was developed for the determination of corosolic acid, a potential anti-diabetes substance, in rat plasma using glycyrrhetinic acid as the internal standard (IS)...
  55. Orcajo B, Muruzabal F, Isasmendi M, Gutierrez N, Sanchez M, Orive G, et al. The use of plasma rich in growth factors (PRGF-Endoret) in the treatment of a severe mal perforant ulcer in the foot of a person with diabetes. Diabetes Res Clin Pract. 2011;93:e65-7 pubmed publisher
    ..old person with diabetes with a severe mal perforant ulcer in the right foot was treated twice with autologous plasma-rich in growth factors (PRGF) obtained from her own blood...
  56. Kim D, Linnstaedt S, Palma J, Park J, Ntrivalas E, Kwak Kim J, et al. Plasma components affect accuracy of circulating cancer-related microRNA quantitation. J Mol Diagn. 2012;14:71-80 pubmed publisher
    ..Overall, the present study outlines key factors that prevent accurate miRNA quantitation in body fluids and provides approaches that enable faithful quantitation of miRNA abundance in body fluids...
  57. Yu Z, Kastenmüller G, He Y, Belcredi P, Moller G, Prehn C, et al. Differences between human plasma and serum metabolite profiles. PLoS ONE. 2011;6:e21230 pubmed publisher
    Human plasma and serum are widely used matrices in clinical and biological studies. However, different collecting procedures and the coagulation cascade influence concentrations of both proteins and metabolites in these matrices...
  58. Tenzer S, Docter D, Rosfa S, Wlodarski A, Kuharev J, Rekik A, et al. Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis. ACS Nano. 2011;5:7155-67 pubmed publisher
    ..We studied the long-lived ("hard") blood plasma derived corona on monodispersed amorphous silica nanoparticles differing in size (20, 30, and 100 nm)...
  59. Konno T, Hata S, Hamada Y, Horikoshi Sakuraba Y, Nakaya T, Saito Y, et al. Coordinated increase of ?-secretase reaction products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alc? with a new ELISA system. Mol Neurodegener. 2011;6:76 pubmed publisher
  60. Springer J, Schloßnagel H, Heinz W, Doedt T, Soeller R, Einsele H, et al. A novel extraction method combining plasma with a whole-blood fraction shows excellent sensitivity and reproducibility for patients at high risk for invasive aspergillosis. J Clin Microbiol. 2012;50:2585-91 pubmed publisher
    ..The standardized UCP extraction method yielded superior results, with regard to sensitivity and reproducibility, than the in-house method. This was independent of the PCR assay used to detect fungal DNA in the sample extracts...
  61. O Bryant S, Xiao G, Barber R, Huebinger R, Wilhelmsen K, Edwards M, et al. A blood-based screening tool for Alzheimer's disease that spans serum and plasma: findings from TARC and ADNI. PLoS ONE. 2011;6:e28092 pubmed publisher
    ..There is no rapid and cost effective tool that can be implemented as a front-line screening tool for Alzheimer's disease (AD) at the population level...
  62. Witwer K, Watson A, Blankson J, Clements J. Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients. Retrovirology. 2012;9:5 pubmed publisher
    ..Using samples from a well-characterized ES cohort, untreated viremic patients, and uninfected controls, we explored the PBMC miRNA profile and probed the relationships of miRNA expression, CD4+ T-cell counts, and viral load...
  63. O Kane A, Chevallier O, Graham S, Elliott C, Mooney M. Metabolomic profiling of in vivo plasma responses to dioxin-associated dietary contaminant exposure in rats: implications for identification of sources of animal and human exposure. Environ Sci Technol. 2013;47:5409-18 pubmed publisher
    ..1 ?g/kg TEQ) and acquired plasma was subsequently biochemically profiled using ultra high performance liquid chromatography (UPLC) quadropole time-..
  64. Ahn Y, Shin P, Oh N, Park G, Kim H, Yoo J. A lectin-coupled, targeted proteomic mass spectrometry (MRM MS) platform for identification of multiple liver cancer biomarkers in human plasma. J Proteomics. 2012;75:5507-15 pubmed publisher
    ..proteins related to liver cancer progression were captured with specific lectin and identified from human plasma by multiple reaction monitoring (MRM) mass spectrometry as multiple biomarkers for hepatocellular carcinoma (HCC)...
  65. Lanteri P, Lombardi G, Colombini A, Grasso D, Banfi G. Stability of osteopontin in plasma and serum. Clin Chem Lab Med. 2012;50:1979-84 pubmed
    ..We evaluated the effects of different times and temperatures storage conditions on serum and plasma concentrations of osteopontin.