Genomes and Genes
Summary: Solutions having the same osmotic pressure as blood serum, or another solution with which they are compared. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)
Publications245 found, 100 shown here
- Randomised controlled trial of intravenous maintenance fluidsMichael Yung
Paediatric Intensive Care Unit, Women s and Children s Hospital, South Australia, Australia
J Paediatr Child Health 45:9-14. 2009..However, this may cause hyponatraemia in sick and post-operative children. We studied the effect of two types of intravenous maintenance fluid and two administration rates on plasma sodium concentration in intensive care patients...
- Comparison of three fluid solutions for resuscitation in dengue shock syndromeBridget A Wills
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
N Engl J Med 353:877-89. 2005..Although volume replacement is recognized as the critical therapeutic intervention, World Health Organization management guidelines remain empirical rather than evidence-based...
- The effect of intravenous lactated Ringer's solution versus 0.9% sodium chloride solution on serum osmolality in human volunteersE L Williams
Anesthesiology Department, Allegheny University Hospitals, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA
Anesth Analg 88:999-1003. 1999..001). In healthy humans, an infusion of large volumes of LR, but not NS, transiently decreased serum osmolality, whereas acidosis associated with NS persisted and urinary output was slower with NS...
- Colloids versus crystalloids for fluid resuscitation in critically ill patientsPablo Perel
Cochrane Injuries Group, London School of Hygiene and Tropical Medicine, London, UK
Cochrane Database Syst Rev 6:CD000567. 2012..Colloid solutions are widely used in fluid resuscitation of critically ill patients. There are several choices of colloid and there is ongoing debate about the relative effectiveness of colloids compared to crystalloid fluids...
- A rational approach to perioperative fluid managementDaniel Chappell
Clinic of Anesthesiology, Ludwig Maximilians University, Munich, Germany
Anesthesiology 109:723-40. 2008..Therefore, undifferentiated fluid handling may increase the shift toward the interstitial space. Using the right kind of fluid in appropriate amounts at the right time might improve patient outcome...
- A balanced view of balanced solutionsBertrand Guidet
INSERM, Unité de Recherche en Épidémiologie Systèmes d Information et Modélisation U707, Paris F 75012, France
Crit Care 14:325. 2010....
- Fluid resuscitation: past, present, and the futureHeena P Santry
Department of Surgery, Division of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital Harvard Medical School, Boston, MA 02114, USA
Shock 33:229-41. 2010..Thus, we describe how some novel resuscitation strategies aimed at preventing or ameliorating cellular injury may become clinically available in the future...
- Greater cardiac response of colloid than saline fluid loading in septic and non-septic critically ill patients with clinical hypovolaemiaRonald J Trof
Department of Intensive Care, Medical Spectrum Twente, Haaksbergerstraat 55, 7513 ER, Enschede, The Netherlands
Intensive Care Med 36:697-701. 2010..The haemodynamics of crystalloid and colloid fluid loading may depend on underlying disease, i.e. sepsis versus non-sepsis...
- Secondary abdominal compartment syndrome after severe extremity injury: are early, aggressive fluid resuscitation strategies to blame?Michael C Madigan
Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee, USA
J Trauma 64:280-5. 2008..We hypothesized that poor resuscitation techniques, including early and excessive crystalloid administration, places patients with extremity injuries at risk for developing secondary ACS...
- Crystalloid resuscitation improves survival in trauma patients receiving low ratios of fresh frozen plasma to packed red blood cellsNicholas Spoerke
Division of Trauma and Critical Care, Oregon Health and Science University, Portland, Oregon 97239, USA
J Trauma 71:S380-3. 2011..Our aim was to determine whether the volume of crystalloid given during resuscitation correlated with differences in morbidity or mortality based on the ratio of FFP:PRBC given...
- A comparison of flow rates and warming capabilities of the Level 1 and Rapid Infusion System with various-size intravenous cathetersSandra L Barcelona
Department of Anesthesiology, Northwestern University, The Feinberg School of Medicine, Department of Pediatric Anesthesiology, Children s Memorial Hospital, Chicago, Illinois 60614, USA
Anesth Analg 97:358-63, table of contents. 2003..e., those used for cases with massive blood loss. The RIS provided no advantage (with regard to heating and flow) when used with typical pediatric-sized catheters...
- Effects on coagulation of balanced (130/0.42) and non-balanced (130/0.4) hydroxyethyl starch or gelatin compared with balanced Ringer's solution: an in vitro study using two different viscoelastic coagulation tests ROTEMTM and SONOCLOTTMM Casutt
Institute of Anesthesiology and Intensive Care, Kantonsspital Lucerne, Lucerne, Switzerland
Br J Anaesth 105:273-81. 2010..42 solution (HES(BAL)), a saline-based 6% HES 130/0.4 solution (HES(SAL)), a balanced lactated Ringer's solution (RL) and a saline-based 4% gelatin solution (GEL)...
- The inflammatory response to colloids and crystalloids used for pump priming during cardiopulmonary bypassE Tamayo
Department of Anaesthesiology and Reanimation, Valladolid University Hospital, Valladolid, Spain
Acta Anaesthesiol Scand 52:1204-12. 2008..This study tests the hypothesis that the priming of the extracorporeal circuit with colloid solutions results in less inflammation in patients undergoing cardiac surgery than priming with crystalloid solutions...
- Hydroxyethyl starch (130 kD), but not crystalloid volume support, improves microcirculation during normotensive endotoxemiaJohannes N Hoffmann
Department of Surgery, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
Anesthesiology 97:460-70. 2002....
- Crystalloids versus colloids for goal-directed fluid therapy in major surgeryLuzius B Hiltebrand
Department of Anaesthesiology and Pain Therapy, Inselspital, Bern University Hospital, Freiburgstrasse, Bern, CH 3010, Switzerland
Crit Care 13:R40. 2009....
- The meaning of acid-base abnormalities in the intensive care unit: part III -- effects of fluid administrationThomas J Morgan
Adult Intensive Care, Mater Misericordiae Hospitals, Brisbane, Australia
Crit Care 9:204-11. 2005..Thus, Stewart's approach not only explains fluid induced acid-base phenomena but also provides a framework for the design of fluids for specific acid-base effects...
- The cellular, metabolic, and systemic consequences of aggressive fluid resuscitation strategiesBryan A Cotton
Department of General Surgery, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
Shock 26:115-21. 2006..Future resuscitation research is likely to focus on improvements in fluid composition and adjuncts to administration of large volume of fluid...
- Cardiac response is greater for colloid than saline fluid loading after cardiac or vascular surgeryJoanne Verheij
Department of Intensive Care, VU Medical Centre, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
Intensive Care Med 32:1030-8. 2006..To study the effects on volume expansion and myocardial function of colloids or crystalloids in the treatment of hypovolaemic hypotension after cardiac and major vascular surgery...
- Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: a prospective sequential comparisonOle Bayer
Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany
Crit Care Med 39:1335-42. 2011..4 and gelatin are considered to be less harmful. We hypothesized that fluid therapy with only crystalloids would decrease the incidence of acute kidney injury...
- The effect of different crystalloid solutions on acid-base balance and early kidney function after kidney transplantationNecmiye Hadimioglu
Department of Anesthesiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey
Anesth Analg 107:264-9. 2008..This study aimed to quantify changes in acid-base balance, potassium and lactate levels as a function of administration of different crystalloid solutions during kidney transplantation, and to determine the ideal fluid for such patients...
- Acute intravascular volume expansion with rapidly administered crystalloid or colloid in the setting of moderate hypovolemiaDavid R McIlroy
Department of Anesthesiology, University of Washington Medical Center, Seattle, USA
Anesth Analg 96:1572-7, table of contents. 2003....
- The use of isotonic fluid as maintenance therapy prevents iatrogenic hyponatremia in pediatrics: a randomized, controlled open studyP Alvarez Montañana
Pediatric Intensive Care Unit, Hospital La Fe, Valencia, Spain
Pediatr Crit Care Med 9:589-97. 2008..We primarily intend to determine whether the use of isotonic fluids prevents hyponatremia and, secondly, whether these fluids increase the incidence of adverse events...
- Isotonic is better than hypotonic saline for intravenous rehydration of children with gastroenteritis: a prospective randomised studyK A Neville
Department of Endocrinology, Sydney Children s Hospital, Sydney, Australia
Arch Dis Child 91:226-32. 2006..To determine whether the risk of hyponatraemia in children with gastroenteritis receiving intravenous (IV) fluids is decreased by the use of 0.9% saline...
- Role of pump prime in the etiology and pathogenesis of cardiopulmonary bypass-associated acidosisF J Liskaser
Departments of Anaesthesia and Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Australia
Anesthesiology 93:1170-3. 2000..Accordingly, acid-base changes induced by the establishment of CPB were studied using two types of priming fluid (Haemaccel, a polygeline solution, and Ringer's Injection vs. Plasmalyte 148) using quantitative biophysical methods...
- Crystalloid strong ion difference determines metabolic acid-base change during in vitro hemodilutionThomas J Morgan
Division of Anesthesiology and Intensive Care, Royal Brisbane Hospital, Queensland, Australia
Crit Care Med 30:157-60. 2002..To determine the relationship between the strong ion difference (SID) of a diluting crystalloid and its metabolic acid-base effects on in vitro blood dilution...
- Elevation in compartment pressure following hypovolemic shock and fluid resuscitation: a canine modelRobert H Ablove
Department of Orthopedics and Rehabilitation, University of Wisconsin Medical School, Madison, USA
Orthopedics 29:443-5. 2006..While this elevation may not be sufficient enough to cause a compartment syndrome, it reinforces the notion that extremities that have experienced ischemia and reperfusion are at an increased risk for developing compartment syndrome...
- Resuscitation with hydroxyethyl starch solution prevents nuclear factor kappaB activation and oxidative stress after hemorrhagic shock and resuscitation in ratsMing Che Tsai
Department of Emergency Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
Shock 27:527-33. 2007..HES solution was an appropriate resuscitation fluid in reversing nuclear factor kappaB activation, maintaining the Bcl-2/Bax ratio, and preventing oxidative stress after acute HS...
- D-lactate increases pulmonary apoptosis by restricting phosphorylation of bad and eNOS in a rat model of hemorrhagic shockAmin Jaskille
Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
J Trauma 57:262-69; discussion 269-70. 2004..These modified solutions however alter the function of apoptotic proteins through an unknown mechanism. We postulated that DL-LR induces apoptosis by restricting the phosphorylation of key apoptotic proteins...
- Fluid therapy in uncontrolled hemorrhage--what experimental models have taught usR G Hahn
Anaesthesia and Intensive Care, Linkoping University, Linkoping, Sweden
Acta Anaesthesiol Scand 57:16-28. 2013..For a hemorrhage of 1000 ml, computer simulations show that deliberate hypovolemia (-300 ml) would be achieved by infusing 600-750 ml crystalloid fluid over 20-30 min or 100 ml of HSD over 10-20 min in an adult male...
- Effects of normal saline vs. lactated ringer's during renal transplantationMohammad Reza Khajavi
Department of Anesthesiology, Sina Hospital, Medical Sciences University of Tehran, Tehran, Iran
Ren Fail 30:535-9. 2008..Thus, the aim of this study was to determine the safety of LR if used during a renal transplant...
- Comparisons of lactated Ringer's and Hextend resuscitation on hemodynamics and coagulation following femur injury and severe hemorrhage in pigsWenjun Z Martini
US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, USA
J Trauma Acute Care Surg 74:732-9; discussion 739-40. 2013..This study compared coagulation function after resuscitation with Hextend and lactated Ringer's (LR) solution in pigs with tissue injury and hemorrhagic shock...
- Osmosensitive taurine transporter expression and activity in human corneal epithelial cellsRyo Shioda
Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan
Invest Ophthalmol Vis Sci 43:2916-22. 2002..To evaluate whether medium supplementation with taurine improves cell viability during a hypertonic challenge...
- Identification of expression patterns associated with hemorrhage and resuscitation: integrated approach to data analysisHuazhen Chen
Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
J Trauma 60:701-23; discussion 723-4. 2006....
- Hypertonic saline improves tissue oxygenation and reduces systemic and pulmonary inflammatory response caused by hemorrhagic shockValter Gurfinkel
Department of Clinical Emergencies, Hospital das Clinicas, University of Sao Paulo, Brazil
J Trauma 54:1137-45. 2003....
- Effects of different resuscitation fluids on acute lung injury in a rat model of uncontrolled hemorrhagic shock and infectionJu Gao
Department of Anesthesiology, The People s Hospital of Qingyuan, Guangdong, China
J Trauma 67:1213-9. 2009..To investigate the effects of different resuscitation fluids on acute lung injury in a rat model of uncontrolled hemorrhagic shock (HS) followed by mimicked infection...
- Diluting the benefits of hemostatic resuscitation: a multi-institutional analysisJuan Carlos Duchesne
Section of Trauma and Critical Care Surgery, Department of Surgery, Anesthesia, Emergency Medicine, Tulane University School of Medicine, New Orleans, Louisiana 70112 2699, USA
J Trauma Acute Care Surg 75:76-82. 2013..We hypothesize that HRR patients will have worse outcomes from crystalloid use...
- The history of 0.9% salineSherif Awad
Division of Gastrointestinal Surgery, Wolfson Digestive Diseases Centre, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
Clin Nutr 27:179-88. 2008..We aimed to trace the historical origins of 0.9% saline, how it came to be used so commonly today, and to consider whether its continued use can be justified...
- Crystalloid strong ion difference determines metabolic acid-base change during acute normovolaemic haemodilutionThomas J Morgan
Adult Intensive Care Unit, Mater Misericordiae Hospital, Raymond Terrace, 4101 South Brisbane, Queensland, Australia
Intensive Care Med 30:1432-7. 2004..To study the acid-base effects of crystalloid strong ion difference (SID) during haemodilution...
- The effects of colloid solutions on renal proximal tubular cells in vitroWinfried Neuhaus
Department of Anaesthesia and Critical Care, University Hospital Wurzburg, Wurzburg, Germany
Anesth Analg 114:371-4. 2012..HES130/0.4 exhibited the most distinctive harmful impact, whereas the application of crystalloid Sterofundin ISO revealed cytoprotective effects...
- Comparison of the effects of gelatin, Ringer's solution and a modern hydroxyl ethyl starch solution after coronary artery bypass graft surgeryS M Alavi
Department of Anaesthesiology and Intensive Care Medicine, Rajaei Heart Centre, Tehran University of Medical Sciences, Tehran, Iran
Cardiovasc J Afr 23:428-31. 2012....
- Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adultsNor azim Mohd Yunos
Affiliations Johor Bahru Clinical School, Monash University Sunway Campus, Malaysia
JAMA 308:1566-72. 2012..Administration of traditional chloride-liberal intravenous fluids may precipitate acute kidney injury (AKI)...
- The effect of HES (130/0.4) usage as the priming solution on renal function in children undergoing cardiac surgeryFulya G Akkucuk
Department of Anesthesiology and Reanimation, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Ren Fail 35:210-5. 2013..Experience with hydroxyethyl starch (HES) in children is limited. This study was conducted to observe the effects of HES or Ringer's lactate (RL) usage as the priming solution on renal functions in children undergoing cardiac surgery...
- Influence of low-molecular-weight hydroxyethyl starch on microvascular permeability in patients undergoing abdominal surgery: comparison with crystalloidYuko Ando
Department of Anesthesia, Nagasaki Rosai Hospital, 2 12 5 Setogoe, Sasebo, Nagasaki, 857 0134, Japan
J Anesth 22:391-6. 2008..This study was carried out to evaluate the effect of low-molecular-weight HES on the urinary microalbumin/creatinine ratio (MACR), a marker of microvascular permeability, in surgical patients...
- Clinical benefits after the implementation of a protocol of restricted perioperative intravenous crystalloid fluids in major abdominal operationsJosé E de Aguilar-Nascimento
Department of Surgery, Medical Sciences School, The Federal University of Mato Grosso, Rua Estevao de Mendonca, 81 apto 801, 78043 300, Cuiaba, MT, Brazil
World J Surg 33:925-30. 2009..The purpose of the present study was to investigate the effect of two different perioperative hydration protocols on the outcome in patients undergoing major abdominal operations...
- Hydroxyethyl starch versus Ringer solution in cardiopulmonary bypass prime solutions (a randomized controlled trial)Osman Tiryakioglu
Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey
J Cardiothorac Surg 3:45. 2008..4 solution, which can be a potential alternative prime solution with an indispensable material for the cardio-pulmonary bypass applications...
- Fluid management for laparoscopic colectomy: a prospective, randomized assessment of goal-directed administration of balanced salt solution or hetastarch coupled with an enhanced recovery programA J Senagore
Spectrum Health, Grand Rapids, Michigan, USA
Dis Colon Rectum 52:1935-40. 2009....
- Randomized evaluation of fluid resuscitation with crystalloid (saline) and colloid (polymer from degraded gelatin in saline) in pediatric septic shockManasaranjan Upadhyay
Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Indian Pediatr 42:223-31. 2005..To compare the efficacy of crystalloid (Normal saline) and colloid (polymer from degraded Gelatin in saline Haemaccel) intravenous fluid in restoration of circulating volume in children with septic shock...
- Colloid vs. crystalloid infusions in gastrointestinal surgery and their different impact on the healing of intestinal anastomosesGoran Marjanovic
Department of Surgery, University of Freiburg, Freiburg, Germany
Int J Colorectal Dis 25:491-8. 2010..The aim of this study was to investigate if colloid infusions have different effects on intestinal anastomotic healing when compared to crystalloid infusions depending on the amount of the administered volume...
- [Hydroxyethyl starch to protect renal function in laparoscopic surgery]J L Jover
Servicio de Anestesia, Hospital Verge dels Lliris, Alcoy, Alicante
Rev Esp Anestesiol Reanim 56:27-30. 2009..To evaluate the effect of prehydration with hydroxyethyl starch 130/0.4 (Voluven) compared to lactated Ringer solution in laparoscopic cholecystectomy...
- A comparison of four different techniques of assisted hatchingBasak Balaban
Assisted Reproduction Unit, American Hospital of Istanbul, Istanbul, Turkey
Hum Reprod 17:1239-43. 2002..The aim of the current study was to compare retrospectively the efficacy of AH performed with four different methods in patients undergoing IVF or ICSI...
- Comparison of effects of zona drilling by non-contact infrared laser or acid Tyrode's on the development of human biopsied embryos as revealed by blastomere viability, cytoskeletal analysis and molecular cytogeneticsKaterina Chatzimeletiou
The London Bridge Fertility, Gynaecology and Genetics Centre, London SE1 9RY, UK
Reprod Biomed Online 11:697-710. 2005..Acid Tyrode's drilling can also cause damage, and tended to retard blastocyst development...
- Comparison between Ringer's lactate and balanced salt solution on postoperative outcomes after phacoemulsfication: a randomized clinical trialViraj Vasavada
IOL Research Centre, Raghudeep Eye Clinic, Memnagar, Ahmedabad, India
Indian J Ophthalmol 57:191-5. 2009..To compare the effects of balanced salt solution (BSS) and Ringer's lactate (RL) on corneal thickness, endothelial morphology, and postoperative anterior chamber inflammation in eyes undergoing phacoemulsification...
- Effect of pump prime on acidosis, strong-ion-difference and unmeasured ions during cardiopulmonary bypassF Liskaser
Department of Anaesthesia, Austin Health, Heidelberg, Victoria, Australia
Anaesth Intensive Care 37:767-72. 2009..We suggest future studies examine other possible mechanisms including unmeasured ions...
- Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shockRunkuan Yang
Department of Critical Care Medicine, University of Pittsburgh School of Medicine, PA 15621, USA
Mol Med 12:105-14. 2006..These data support the notion that HMGB1 is a mediator of HS/R-induced gut barrier dysfunction and suggest that anti-HMGB1 antibodies warrant further evaluation as a therapeutic to ameliorate the morbidity of HS/R in trauma patients...
- Inappropriate perioperative fluid management in children: time for an isotonic solution?! Author's replyPer Arne Lonnqvist
Paediatr Anaesth 18:271. 2008
- The impact of crystalloid and colloid infusion on the kidney in rodent sepsisMartin Alexander Schick
Klinik und Poliklinik für Anästhesiologie, Zentrum für Operative Medizin, University of Wurzburg, Oberdürrbacherstrasse 6, 97080 Wurzburg, Germany
Intensive Care Med 36:541-8. 2010..We therefore determined the impact of crystalloid and colloid solutions on kidney function in a rodent model of abdominal sepsis induced by cecal ligation and puncture (CLP)...
- Prospective study on cardiopulmonary bypass prime reduction and its effect on intraoperative blood product and hemoconcentrator useMichael A Sobieski
Division of Cardiac Surgery, Advocate Christ Medical Center, Oak Lawn, IL, USA
Perfusion 20:31-7. 2005..Evaluate the feasibility and clinical significance of crystalloid prime reduction during the initiation of cardiopulmonary bypass (CPB) using a modified bridge on the cardioplegia delivery system...
- Rubbing salt in the woundM Hatherill
Paediatric Intensive Care Unit, Institute of Child Health, Red Cross Children s Hospital, Klipfontein Road, Cape Town, 7700, South Africa
Arch Dis Child 89:414-8. 2004
- Acid-base effects of a bicarbonate-balanced priming fluid during cardiopulmonary bypass: comparison with Plasma-Lyte 148. A randomised single-blinded studyT J Morgan
Department of Anaesthesia, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Anaesth Intensive Care 36:822-9. 2008..These are likely to be gluconate and/or acetate. Whether surges of exogenous anions during bypass can be harmful requires further study...
- Small increases in extravascular lung water are accurately detected by transpulmonary thermodilutionEnrique Fernandez-Mondejar
Hospital Universitario Virgen de las Nieves, Granada, Spain
J Trauma 59:1420-3; discussion 1424. 2005..Detection of small (10-20%) increases in lung water may be relevant to detect incipient pulmonary edema but no clinically usable method has demonstrated this capability to date...
- Comparison of laser-assisted hatching and acidified Tyrode's hatching by evaluation of blastocyst development rates in sibling embryos: a prospective randomized trialAmy E Jones
Reproductive Biology Associates, Atlanta, Georgia, USA
Fertil Steril 85:487-91. 2006..To assess two zona drilling methods in terms of blastocyst development rates using sister embryos...
- CONTRA: Hydroxyethyl starch solutions are unsafe in critically ill patientsChristiane Hartog
Department of Anaesthesiology and Intensive Care Medicine, Friedrich Schiller University, Erlanger Allee 101, 07747 Jena, Germany
Intensive Care Med 35:1337-42. 2009..To describe the risk-benefit profile of hydroxyethyl starch (HES)...
- Incidence of postoperative hyponatremia and complications in critically-ill children treated with hypotonic and normotonic solutionsAlicia K Au
Department of Pediatrics, Children s National Medical Center, Washington, DC, USA
J Pediatr 152:33-8. 2008..To determine the incidence and clinical consequences of postoperative hyponatremia in children...
- A randomized, double-blind comparison of lactated Ringer's solution and 0.9% NaCl during renal transplantationCatherine M N O'Malley
Department of Anesthesia, Columbia University College of Physicians and Surgeons, New York, NY, USA
Anesth Analg 100:1518-24, table of contents. 2005..004). NS did not adversely affect renal function. LR was associated with less hyperkalemia and acidosis compared with NS. LR may be a safe choice for IV fluid therapy in patients undergoing kidney transplantation...
- Early postoperative respiratory acidosis after large intravascular volume infusion of lactated ringer's solution during major spine surgeryArzu Takil
Department of Anesthesiology, Medical Faculty of Marmara University, Istanbul, Turkey
Anesth Analg 95:294-8, table of contents. 2002..Although intraoperative 20 mL. kg(-1). h(-1) LR infusion does not cause hyperchloremic metabolic acidosis as does NS infusion, it leads to postoperative respiratory acidosis and mild hyponatremia...
- Distribution of normal saline and 5% albumin infusions in septic patientsD Ernest
Intensive Care Unit, St Paul s Hospital and University of British Columbia, Vancouver, Canada
Crit Care Med 27:46-50. 1999..CONCLUSION: Expansion of the ECFV in excess of the volume of 5% albumin infused suggests that fluid may move from the intracellular fluid volume to the ECFV in septic patients who receive this fluid...
- Crystalloid or colloid fluid loading and pulmonary permeability, edema, and injury in septic and nonseptic critically ill patients with hypovolemiaMelanie van der Heijden
Department of Intensive Care, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
Crit Care Med 37:1275-81. 2009..We hypothesized that 1) crystalloid loading results in more edema formation than colloid loading and 2) the differences among the types of fluid decreases at high permeability...
- Perioperative fluid management: comparison of high, medium and low fluid volume on tissue oxygen pressure in the small bowel and colonL B Hiltebrand
Washington University, Department of Anesthesiology, St Louis, MO, USA
Eur J Anaesthesiol 24:927-33. 2007..We tested the hypothesis that high intraoperative fluid volume administration increases intestinal wall tissue oxygen pressure during laparotomy...
- Effect of intraoperative fluid management on outcome after intraabdominal surgeryVadim Nisanevich
Department of Anesthesia and Critical Care Medicine, Hadassah Hebrew University and Medical Center, Jerusalem, Israel
Anesthesiology 103:25-32. 2005..The debate over the correct perioperative fluid management is unresolved...
- Cold-induced fluid extravasation during cardiopulmonary bypass in piglets can be counteracted by use of iso-oncotic primeMarit Farstad
Department of Anesthesia and Intensive Care, University of Bergen, Haukeland University Hospital, Bergen, Norway
J Thorac Cardiovasc Surg 130:287-94. 2005..This study aimed to compare whether iso-oncotic priming solutions, in contrast to crystalloids, could reduce the cold-induced fluid extravasation during cardiopulmonary bypass in piglets...
- Comparison of the effects of lactated Ringer solution with and without hydroxyethyl starch fluid resuscitation on gut edema during severe splanchnic ischemiaS M Lobo
Serviço de Terapia Intensiva, Departamento de Medicina Interna, Faculdade de Medicina de Rio Preto, Sao Jose do Rio Preto, SP, Brasil
Braz J Med Biol Res 41:634-9. 2008..9 +/- 1.5) than in the crystalloid-treated group (7.3 +/- 2.4) (P < 0.05). In this model of intestinal ischemia, fluid resuscitation with crystalloids caused more gut edema than a combination of crystalloids and colloids...
- Pouring salt on troubled watersD Taylor
Paediatric Intensive Care Unit, Guy s Hospital, London, UK
Arch Dis Child 89:411-4. 2004
- Prehospital induction of therapeutic hypothermia during CPR: a pilot studyAntti Kämäräinen
Medical School, University of Tampere, Tampere, Finland
Resuscitation 76:360-3. 2008..We studied induction of therapeutic hypothermia during prehospital resuscitation from cardiac arrest using an infusion of ice-cold Ringer's solution in five adult patients...
- Normal saline versus lactated Ringer's solution for intraoperative fluid management in patients undergoing abdominal aortic aneurysm repair: an outcome studyJ H Waters
Department of General Anesthesiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Anesth Analg 93:817-22. 2001..These changes should be considered when choosing fluids for surgical procedures involving extensive blood loss and requiring extensive fluid administration...
- Effects of lactated Ringer's solutions on human leukocytesElena Koustova
Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
J Trauma 52:872-8. 2002..The aim of this study was to investigate whether racemic LR solution (containing both isomers, dl-LR) differs from LR containing L-isomer only (L-LR)...
- The influence of priming solutions used in cardiopulmonary bypass on blood viscosity in hypothermic conditionsSinasi Manduz
Cumhuriyet University, Cardiovascular Surgery, Sivas, Turkey
ASAIO J 54:275-7. 2008..Viscosity of all mixtures except RL decreased significantly at deep hypothermia (15 degrees C)...
- Volume replacement with HES 130/0.4 may reduce the inflammatory response in patients undergoing major abdominal surgeryKatrin Lang
Departments of Anesthesiology and Intensive Care Medicine, and Clinical Chemistry, Klinikum der Stadt Ludwigshafen, akademisches Lehrkrankenhaus der Universität Mainz, Ludwigshafen, Germany
Can J Anaesth 50:1009-16. 2003..To investigate the effects of intravascular volume replacement therapy on the inflammatory response during major surgery...
- Acute hospital-induced hyponatremia in children: a physiologic approachMalcolm A Holliday
Department of Pediatrics, University of California, San Francisco, USA
J Pediatr 145:584-7. 2004
- Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shockRunkuan Yang
Department of Critical Care Medicine, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania 15261, USA
Am J Physiol Gastrointest Liver Physiol 283:G212-21. 2002..These data support the view that resuscitation with REPS modulates the inflammatory response and decreases hepatocellular and gut mucosal injury in mice subjected to HS/R...
- Conservative vs restrictive individualized goal-directed fluid replacement strategy in major abdominal surgery: A prospective randomized trialEmmanuel Futier
Department of Anesthesiology and Critical Care, University Hospital of Clermont Ferrand, France
Arch Surg 145:1193-200. 2010....
- A prospective, randomized comparison of thromboelastographic coagulation profile in patients receiving lactated Ringer's solution, 6% hetastarch in a balanced-saline vehicle, or 6% hetastarch in saline during major surgeryG Martin
Department of Anesthesiology, and Division of Biometry, Duke University Medical Center, Durham, NC 27710, USA
J Cardiothorac Vasc Anesth 16:441-6. 2002..To compare the effects of lactated Ringer's solution (LR), 6% hetastarch in a balanced-saline vehicle (HS-BS), and 6% hetastarch in normal saline (HS-NS) on coagulation using thromboelastography...
- Intravenous fluids for seriously ill childrenMalcolm A Holliday
Lancet 363:241; author reply 242. 2004
- A total balanced volume replacement strategy using a new balanced hydoxyethyl starch preparation (6% HES 130/0.42) in patients undergoing major abdominal surgeryJ Boldt
Klinikum der Stadt Ludwigshafen, Department of Anaesthesiology and Intensive Care Medicine, Ludwigshafen, Germany
Eur J Anaesthesiol 24:267-75. 2007....
- [Study protocol of the VISEP study. Response of the SepNet study group]K Reinhart
Anaesthesist 57:723-8. 2008..However, in our opinion this premature action based on wrong assumptions and containing comments by representatives of pharmaceutical companies does not contribute to a serious, unbiased scientific discourse...
- Assessment of intravascular volume by transthoracic echocardiography during therapeutic hypothermia and rewarming in cardiac arrest survivorsJohanna Nordmark
Department of Surgical Sciences Anaesthesiology, Intensive Care, Uppsala University, Sweden
Resuscitation 80:1234-9. 2009..To study haemodynamic effects and changes in intravascular volume during hypothermia treatment, induced by ice-cold fluids and maintained by ice-packs followed by rewarming in patients after resuscitation from cardiac arrest...
- The risk associated with hyperoncotic colloids in patients with shockFrederique Schortgen
Réanimation Médicale, AP HP, Groupe Hospitalier Albert Chenevier, Henri Mondor, 94000 Creteil, France
Intensive Care Med 34:2157-68. 2008..This study assessed the risk of renal adverse events in patients with shock resuscitated using hypo-oncotic colloids, artificial hyperoncotic colloids, hyperoncotic albumin or crystalloids, according to physician's choice...
- Intravenous postoperative fluid prescriptions for children: a survey of practicePolly Davies
Department of Paediatric Surgery, John Radcliffe Hospital, Oxford, UK
BMC Surg 8:10. 2008..We aimed to determine the rates and types of intravenous fluids being prescribed postoperatively for children in the UK...
- Circulatory shock in children: an overviewChristine A McKiernan
Tufts University School of Medicine, Boston, Mass, USA
Pediatr Rev 26:451-60. 2005
- Intensive insulin therapy and pentastarch resuscitation in severe sepsisFrank M Brunkhorst
Department of Anesthesiology and Intensive Care Medicine, Friedrich Schiller University, Jena, Germany
N Engl J Med 358:125-39. 2008..The role of intensive insulin therapy in patients with severe sepsis is uncertain. Fluid resuscitation improves survival among patients with septic shock, but evidence is lacking to support the choice of either crystalloids or colloids...
- Preventing neurological complications from dysnatremias in childrenMichael L Moritz
Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, PA 15213 2538, USA
Pediatr Nephrol 20:1687-700. 2005..Breastfed infants must be monitored closely for insufficient lactation and receive lactation support. Judicious use of infant formula supplementation may be called for until problems with lactation can be corrected...
- Fluid management in burn patients: results from a European survey-more questions than answersJoachim Boldt
Department of Anesthesiology and Intensive Care Medicine, Klinikum der Stadt, Ludwigshafen, Bremserstr 79, D 67063 Ludwigshafen, Germany
Burns 34:328-38. 2008..New results, e.g. importance of goal-directed therapy or data concerning use of albumin in the critically ill, have not yet influenced strategies of volume replacement in the burn patient...
- Urine sodium composition in ambulatory healthy children: hypotonic or isotonic?Michael L Moritz
Division of Nephrology, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2538, USA
Pediatr Nephrol 23:955-7. 2008..9+/-0.4 ml/kg per hour. It was concluded that healthy children generate free water via the excretion ofa hypertonic urine. It is unlikely that 0.9% NaCl would result in hypernatremia when administered in parenteral fluids...
- Effects of large volume, ice-cold intravenous fluid infusion on respiratory function in cardiac arrest survivorsClaudius Jacobshagen
Department of Cardiology and Pneumology, Georg August University, Gottingen, Germany
Resuscitation 80:1223-8. 2009..A larger, randomized and prospective study is required to assess the efficacy and safety of ice-cold fluid infusion for the induction of therapeutic hypothermia...
- Hospital-acquired hyponatremia--why are hypotonic parenteral fluids still being used?Michael L Moritz
Division of Nephrology, Children s Hospital of Pittsburgh, Pittsburgh, PA 15217, USA
Nat Clin Pract Nephrol 3:374-82. 2007....
- Hospital-acquired hyponatremia is associated with excessive administration of intravenous maintenance fluidMark Hatherill
Pediatrics 114:1368; author reply 1368-9. 2004
- A hyperosmolar-colloidal additive to the CPB-priming solution reduces fluid load and fluid extravasation during tepid CPBV Kvalheim
Section for Cardiothoracic Surgery, Department of Heart Disease, Haukeland University Hospital, N 5021 Bergen, Norway
Perfusion 23:57-63. 2008..5) and 112 (1.6) mmol/l in Group H. To conclude: addition of 7.2% hypertonic saline and 6% poly (O-2-hydroxyethyl) starch solution to crystalloid CPB prime reduces fluid needs and FER during tepid CPB...
- Fluid resuscitation increases inflammatory gene transcription after traumatic injuryJennifer M Watters
Oregon Health and Science University, Portland, Oregon, USA
J Trauma 61:300-8; discussion 308-9. 2006..This study aimed to examine effects of resuscitation with lactated Ringer's (LR) and Hextend (HEX) on the inflammatory response after uncontrolled hemorrhagic shock (UHS)...
- [The design of the VISEP trial. Critical appraisal]R Zander
Institut fur Physiologie und Pathophysiologie, Universitat Mainz
Anaesthesist 56:71-7. 2007..Thus, any further advance presentations and interpretations should be shelved in expectation of the authors' publication of all the data, in order to begin further discussions including the flaws in study design listed here...
- Resuscitation with normal saline (NS) vs. lactated ringers (LR) modulates hypercoagulability and leads to increased blood loss in an uncontrolled hemorrhagic shock swine modelLaszlo N Kiraly
Oregon Health and Science University, Portland, Oregon 97239, USA
J Trauma 61:57-64; discussion 64-5. 2006..The purpose of this study was to compare the effects of LR and NS on coagulation in an uncontrolled hemorrhagic swine model. We hypothesized resuscitation with LR would produce hypercoagulability...
- Resuscitation of haemorrhagic shock with normal saline vs. lactated Ringer's: effects on oxygenation, extravascular lung water and haemodynamicsCharles R Phillips
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Oregon Health and Science University, Physicians Pavilion, Suite 340, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
Crit Care 13:R30. 2009..These experiments were designed to determine if differences exist because of crystalloid fluid type in the development of oedema, the impact on oxygenation and the haemodynamic response to fluid administration in early HSR...
- Fluid resuscitation of hypovolemic shock: acute medicine's great triumph for childrenJoseph A Carcillo
Intensive Care Med 32:958-61. 2006
- Progressive scoliosis deformity in intervertebral discIan Stokes; Fiscal Year: 2009..These approaches may include improvements in brace design, new possibilities for muscle rehabilitation, and surgical procedures aimed at early, minimally invasive modification of spinal growth. ..
- Myocilin-induced ER Stress in Trabecular Meshwork CellsSANGLY SRINIVAS; Fiscal Year: 2005..These studies will lead to the development of an essential knowledge base and influence research in the field of glaucoma pathophysiology, diagnostics, and therapeutics. ..
- Venous Hemodynamic Function in Older Hypertensive AdultsWILLIAM FARQUHAR; Fiscal Year: 2006....
- AN INTEGRATED MODEL OF INTERVERTEBRAL DISC FUNCTIONIan Stokes; Fiscal Year: 2006..and the local conditions that can influence its metabolism, eventual composition and function in three-dimensions. ..
- Cytokines in Sickle Cell Volume RegulationAlicia Rivera; Fiscal Year: 2006..abstract_text> ..
- Oxygen Carriers for Hypovolemic Circulatory CollapseRobert Winslow; Fiscal Year: 2007..The research described in this proposal will focus on molecules and formulations specifically tailored for use in prehospital and trauma settings. ..
- Sympathetic - Osmotic Interactions in HumansWILLIAM FARQUHAR; Fiscal Year: 2007..In some, but not all individuals, dietary salt causes blood pressure to increase. The purpose of this project is to determine why salt increases blood pressures in some individuals. [unreadable] [unreadable] [unreadable]..
- MOLECULAR GENETICS OF LOW RENIN HYPERTENSIONPerrin White; Fiscal Year: 2001..The investigators will determine the role of 11-HSD K in the development of essential hypertension, using both linkage and association studies. ..
- Biochemical Basis of Cortisone Reductase DeficiencyPerrin White; Fiscal Year: 2007..Subsets of the genotyping data will be analyzed as an association study, as an affected sib pair study, and by transmission disequilibrium testing. Additional polymorphisms in these genes will be sought in PCOS subjects. ..
- Fluid Movement across Conjunctiva: Stimulation and RegulationOSCAR CANDIA; Fiscal Year: 2007..These studies may provide the groundwork for the design of future treatment modalities for dry-eye syndromes. ..
- Alcohol Enhances HIV-1 Induced Cardiac DepressionKathleen McDonough; Fiscal Year: 2006..The function of the heart will be assessed with the isolated work performing heart and plasma and tissue cytokines and biochemical markers of myocardial oxidative injury and antioxidant capacity will be measured by standard techniques. ..
- Mechanism/regulation of human intestinal thiamin uptakeHAMID SAID; Fiscal Year: 2008..This should ultimately assist us in the designing of effective strategies to optimize thiamin body homeostasis in conditions associated with thiamin deficiency and sub-optimal levels. ..
- Effects of inflammation on developing gliaMichael Bell; Fiscal Year: 2007..Mentorship in neuroscience as well as the resources of the Mental Retardation and Developmental Disabilities Research Center will support these well-defined training objectives. ..
- TRANSMURAL REGULATION Na/K PUMP ACTIVITY IN HEARTRichard Mathias; Fiscal Year: 2009..The aims of this proposal are to test these two hypotheses. We will use a combination of electrophysiological, Na- and Ca-imaging, contraction, and biochemical measurements to accomplish these aims. ..
- Biomimetic Synthesis of an Enamel-Like MaterialStefan Habelitz; Fiscal Year: 2004..abstract_text> ..
- VIRUS PHOTOINACTIVATION--DIMETHYLMETHYLENE BLUE IN RBCStephen Wagner; Fiscal Year: 2004..abstract_text> ..
- STABILITY OF MUSCULAR LOADING OF THE LUMBAR SPINEIan Stokes; Fiscal Year: 2002..In addition, the specific roles of individual muscles will be better elucidated, which will be helpful in guiding therapy for people with low back dysfunction. ..
- REGULATION OF HUMAN ALDOSTERONE SYNTHASEPerrin White; Fiscal Year: 2002..These studies should provide insight into mechanisms underlying a genetic risk factor for cardiovascular disease. ..
- FUNCTION & REGULATION OF GASTRIC NA/K/2CL COTRANSPORTERSChristian Lytle; Fiscal Year: 2002..Completion of these aims will begin to clarify the functional consequences of the migration-associated differentiation of parietal cells. ..
- VOLUME REGULATION IN CORNEAL ENDOTHELIUMSANGLY SRINIVAS; Fiscal Year: 2002..abstract_text> ..
- UNIQUE MECHANISM FOR REABSORPTION OF EDEMA IN THE LUNGRichard Effros; Fiscal Year: 2002..The effects of lung injury caused by high vascular pressures, over distention of the lungs, acid aspiration and infections of the oleic acid will be investigated. ..
- MECHANICAL MODULATION OF GROWTH IN PHYSESIan Stokes; Fiscal Year: 2003..abstract_text> ..
- SOLUTE AND FLUID TRANSPORT ACROSS THE CONJUNCTIVAOSCAR CANDIA; Fiscal Year: 2002..Based on this model, he will devise protocols to modify and possibly reverse the secretory/absorptive properties of the tissue. ..
- MENTORED PATIENT ORIENTED RESEARCH CAREER DEVELOPMENT AWMargaret Rosenfeld; Fiscal Year: 2004..The results and experience gained by the proposed studies may aid in the rigorous conduct of future clinical trials of inhaled agents in infants both with and without CF. ..
- Towards a Non-Invasive Therapy for Atrial FibrillationBenjamin Scherlag; Fiscal Year: 2004..This new therapeutic approach could be utilized as a non-invasive application or incorporated into an implantable device for treatment of patients with PAF. ..
- REGULATION OF NA/K PUMP CURRENT IN THE HEARTRichard Mathias; Fiscal Year: 2004..It will also be used to characterize regulation of pump current in SA node pacemaker cells and determine if regulation of pump current (particularly the alpha2 isoform) affects pacemaking. ..
- Functions of Very Large G-protein Coupled Receptor-1Perrin White; Fiscal Year: 2008..We are specifically interested in the other proteins with very large ectodomains, protocadherin- 15 and cadherin-23. These studies should shed new light on mechanisms controlling development of the retina and inner ear. ..
- RHEOLOGICAL DETERMINANTS OF MICROVASCULAR FUNCTIONHERBERT LIPOWSKY; Fiscal Year: 2009..The results of these studies will provide insight into the role of hemodynamic interactions with the microvessel wall and aid development of therapeutic strategies to treat ischemia and inflammation. ..
- Mechanisms of Myocardial Radiofrequency Scar ExpansionRupak Mukherjee; Fiscal Year: 2004..abstract_text> ..
- Measurement of Fluid Flow Across the Ocular Ciliary BodyOSCAR CANDIA; Fiscal Year: 2006..abstract_text> ..
- C elegans:a model to study intestinal water-soluble vitamins transport in vivoHAMID SAID; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Inhaled Large Porous Particles for Treatment of MDR-TBDavid Edwards; Fiscal Year: 2006..It represents a new paradigm for treating and limiting the spread (especially nosocomial transmission) of respiratory infectious diseases such as TB, severe acute respiratory syndrome (SARS), influenza, and small pox. ..
- CHANNEL-MEDIATED RBC DEHYDRATION IN SICKLE CELL DISEASEAlicia Rivera; Fiscal Year: 2003..It is additionally significant, because it will provide the means for the applicant to establish an independent research career and to become competitive for a tenure-track assistant professional position. ..
- The Effect of Hypertonic Resuscitation for Blunt TraumaEileen Bulger; Fiscal Year: 2005..abstract_text> ..
- Hypertonic Modulation of Inflammation following InjuryEileen M Bulger; Fiscal Year: 2010..The results of these studies will provide valuable information to determine the ultimate therapeutic use of the resuscitation strategy. ..