omentum

Summary

Summary: A double-layered fold of peritoneum that attaches the STOMACH to other organs in the ABDOMINAL CAVITY.

Top Publications

  1. Geminiani M, Panetta A, Pajetta V, Bacci F, Negri L, Maccaferri R, et al. Endodermal sinus tumor of the omentum: case report. Tumori. 2005;91:563-6 pubmed
    We report a case of primary endodermal sinus tumor of the omentum in a 46-year-old woman. The patient had been referred to our hospital for pain in the right abdomen. CT scan revealed a right-sided abdominal mass...
  2. Bigham Sadegh A, Karimi I, Alebouye M, Shafie Sarvestani Z, Oryan A. Evaluation of bone healing in canine tibial defects filled with cortical autograft, commercial-DBM, calf fetal DBM, omentum and omentum-calf fetal DBM. J Vet Sci. 2013;14:337-43 pubmed
    ..was conducted to compare the effects of xenogenic bovine fetal demineralized bone matrix (DBM), commercial DBM, omentum, omentum-calf fetal DBM, cortical autograft and xenogenic cartilage powder on the healing of tibial defects in a ..
  3. Kim T, Kim D, Jung K, Hong Y, Kim S, Park J, et al. The role of omental flap transposition in patients with locoregional recurrent rectal cancer treated with reirradiation. J Surg Oncol. 2010;102:789-95 pubmed publisher
    ....
  4. Saito R, Ishii Y, Ito R, Nagatsuma K, Tanaka K, Saito M, et al. Transplantation of liver organoids in the omentum and kidney. Artif Organs. 2011;35:80-3 pubmed publisher
    ..consisting of three cocultured cells was transplanted under the kidney capsule (kidney group) or into the omentum (omentum group) using BALB/c nude mice. Transplanted liver organoids survived in the kidney or omentum...
  5. Kovsan J, Bluher M, Tarnovscki T, Kloting N, Kirshtein B, Madar L, et al. Altered autophagy in human adipose tissues in obesity. J Clin Endocrinol Metab. 2011;96:E268-77 pubmed publisher
    ..Autophagy is a housekeeping mechanism, involved in metabolic regulation and stress response, shown recently to regulate lipid droplets biogenesis/breakdown and adipose tissue phenotype...
  6. Divoux A, Tordjman J, Lacasa D, Veyrie N, Hugol D, Aissat A, et al. Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss. Diabetes. 2010;59:2817-25 pubmed publisher
    ..We investigated the composition of subcutaneous (scWAT) and omental WAT (oWAT) fibrosis in obesity and its relationship with metabolic alterations and surgery-induced weight loss...
  7. Rajesh R, Heo G, Park M, Nam J, Kim N, Yoon D, et al. Proteomic analysis of bovine omental, subcutaneous and intramuscular preadipocytes during in vitro adipogenic differentiation. Comp Biochem Physiol Part D Genomics Proteomics. 2010;5:234-44 pubmed publisher
    ..Further, all the up-regulated proteins were found to have higher protein expression in omental than subcutaneous or intramuscular depots...
  8. Yildirim A, Aktas A, Nergiz Y, Akkus M. Analysis of human omentum-associated lymphoid tissue components with S-100: an immunohistochemical study. Rom J Morphol Embryol. 2010;51:759-64 pubmed
    Milky spots are opaque patches in the greater omentum. They were first described by von Recklinghausen (1863) in the omentum of rabbits. In man, milky spots are relatively uniform, highly vascularized accumulations of mononuclear cells...
  9. Wahba R, Kleinert R, Prenzel K, Bangard C, Holscher A, Stippel D. Laparoscopic deroofing of nonparasitic liver cysts with or without greater omentum flap. Surg Laparosc Endosc Percutan Tech. 2011;21:54-8 pubmed publisher
    ..The operation is performed with or without a greater omentum flap sutured into the former cyst cavity...
  10. Kriz J, Vilk G, Mazzuca D, Toleikis P, Foster P, White D. A novel technique for the transplantation of pancreatic islets within a vascularized device into the greater omentum to achieve insulin independence. Am J Surg. 2012;203:793-7 pubmed publisher
    The greater omentum with its vascularization and blood flow has been considered as a location for islet transplantation; however, there is a need to provide a controlled and protected site for the islets within the omentum that would be ..

Locale

Detail Information

Publications100

  1. Geminiani M, Panetta A, Pajetta V, Bacci F, Negri L, Maccaferri R, et al. Endodermal sinus tumor of the omentum: case report. Tumori. 2005;91:563-6 pubmed
    We report a case of primary endodermal sinus tumor of the omentum in a 46-year-old woman. The patient had been referred to our hospital for pain in the right abdomen. CT scan revealed a right-sided abdominal mass...
  2. Bigham Sadegh A, Karimi I, Alebouye M, Shafie Sarvestani Z, Oryan A. Evaluation of bone healing in canine tibial defects filled with cortical autograft, commercial-DBM, calf fetal DBM, omentum and omentum-calf fetal DBM. J Vet Sci. 2013;14:337-43 pubmed
    ..was conducted to compare the effects of xenogenic bovine fetal demineralized bone matrix (DBM), commercial DBM, omentum, omentum-calf fetal DBM, cortical autograft and xenogenic cartilage powder on the healing of tibial defects in a ..
  3. Kim T, Kim D, Jung K, Hong Y, Kim S, Park J, et al. The role of omental flap transposition in patients with locoregional recurrent rectal cancer treated with reirradiation. J Surg Oncol. 2010;102:789-95 pubmed publisher
    ....
  4. Saito R, Ishii Y, Ito R, Nagatsuma K, Tanaka K, Saito M, et al. Transplantation of liver organoids in the omentum and kidney. Artif Organs. 2011;35:80-3 pubmed publisher
    ..consisting of three cocultured cells was transplanted under the kidney capsule (kidney group) or into the omentum (omentum group) using BALB/c nude mice. Transplanted liver organoids survived in the kidney or omentum...
  5. Kovsan J, Bluher M, Tarnovscki T, Kloting N, Kirshtein B, Madar L, et al. Altered autophagy in human adipose tissues in obesity. J Clin Endocrinol Metab. 2011;96:E268-77 pubmed publisher
    ..Autophagy is a housekeeping mechanism, involved in metabolic regulation and stress response, shown recently to regulate lipid droplets biogenesis/breakdown and adipose tissue phenotype...
  6. Divoux A, Tordjman J, Lacasa D, Veyrie N, Hugol D, Aissat A, et al. Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss. Diabetes. 2010;59:2817-25 pubmed publisher
    ..We investigated the composition of subcutaneous (scWAT) and omental WAT (oWAT) fibrosis in obesity and its relationship with metabolic alterations and surgery-induced weight loss...
  7. Rajesh R, Heo G, Park M, Nam J, Kim N, Yoon D, et al. Proteomic analysis of bovine omental, subcutaneous and intramuscular preadipocytes during in vitro adipogenic differentiation. Comp Biochem Physiol Part D Genomics Proteomics. 2010;5:234-44 pubmed publisher
    ..Further, all the up-regulated proteins were found to have higher protein expression in omental than subcutaneous or intramuscular depots...
  8. Yildirim A, Aktas A, Nergiz Y, Akkus M. Analysis of human omentum-associated lymphoid tissue components with S-100: an immunohistochemical study. Rom J Morphol Embryol. 2010;51:759-64 pubmed
    Milky spots are opaque patches in the greater omentum. They were first described by von Recklinghausen (1863) in the omentum of rabbits. In man, milky spots are relatively uniform, highly vascularized accumulations of mononuclear cells...
  9. Wahba R, Kleinert R, Prenzel K, Bangard C, Holscher A, Stippel D. Laparoscopic deroofing of nonparasitic liver cysts with or without greater omentum flap. Surg Laparosc Endosc Percutan Tech. 2011;21:54-8 pubmed publisher
    ..The operation is performed with or without a greater omentum flap sutured into the former cyst cavity...
  10. Kriz J, Vilk G, Mazzuca D, Toleikis P, Foster P, White D. A novel technique for the transplantation of pancreatic islets within a vascularized device into the greater omentum to achieve insulin independence. Am J Surg. 2012;203:793-7 pubmed publisher
    The greater omentum with its vascularization and blood flow has been considered as a location for islet transplantation; however, there is a need to provide a controlled and protected site for the islets within the omentum that would be ..
  11. Shudo Y, Miyagawa S, Fukushima S, Saito A, Shimizu T, Okano T, et al. Novel regenerative therapy using cell-sheet covered with omentum flap delivers a huge number of cells in a porcine myocardial infarction model. J Thorac Cardiovasc Surg. 2011;142:1188-96 pubmed publisher
    ..We developed a new implantation method using skeletal myoblast (SMB) sheets, wrapped with an omentum flap as a blood supply to deliver huge numbers of SMBs to the damaged heart...
  12. Lee B, Kim K, Soh K. Visualizing the network of Bonghan ducts in the omentum and peritoneum by using Trypan blue. J Acupunct Meridian Stud. 2009;2:66-70 pubmed publisher
    ..In addition, tracing BHDs in adipose tissues became possible because Trypan blue does not stain adipose tissue...
  13. Porzionato A, Sfriso M, Macchi V, Rambaldo A, Lago G, Lancerotto L, et al. Decellularized omentum as novel biologic scaffold for reconstructive surgery and regenerative medicine. Eur J Histochem. 2013;57:e4 pubmed publisher
    ..work is to evaluate the possibility of obtaining homologous acellular scaffolds from decellularization of the omentum, which is known to have a complex vascular network...
  14. Dhanasekaran M, Indumathi S, Rajkumar J, Sudarsanam D. Effect of high glucose on extensive culturing of mesenchymal stem cells derived from subcutaneous fat, omentum fat and bone marrow. Cell Biochem Funct. 2013;31:20-9 pubmed publisher
    ..Thus, this study focuses on the effect of high glucose on mesenchymal stem cells derived from subcutaneous fat, omentum fat and bone marrow in extensive cultures...
  15. Cai J, Tang H, Xu L, Wang X, Yang C, Ruan S, et al. Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness. Carcinogenesis. 2012;33:20-9 pubmed publisher
    b>Omentum metastasis is a common occurrence in epithelial ovarian cancer (EOC), which is often accompanied by ascites that facilitates the spread of EOC cells...
  16. Cho H, Kim S, Lee S, Moon S, Park J. Pseudotumor of the omentum associated with migration of the ingested crab-leg. J Korean Med Sci. 2012;27:569-71 pubmed publisher
    ..The patient underwent an antrectomy, a vagotomay, and a transverse colon wedge resection. We present this unusual case of a pseudotumorous lesion caused by ingestion of Kanjang-gaejang...
  17. Bigham Sadegh A, Mirshokraei P, Karimi I, Oryan A, Aparviz A, Shafiei Sarvestani Z. Effects of adipose tissue stem cell concurrent with greater omentum on experimental long-bone healing in dog. Connect Tissue Res. 2012;53:334-42 pubmed publisher
    ..In this study, the role of greater omentum as a scaffold incorporation of ASCs was evaluated in long-bone defect healing in dog model...
  18. Herrera M, Pantoja J, Velazquez Fernandez D, Cabiedes J, Aguilar Salinas C, García García E, et al. Potential additional effect of omentectomy on metabolic syndrome, acute-phase reactants, and inflammatory mediators in grade III obese patients undergoing laparoscopic Roux-en-Y gastric bypass: a randomized trial. Diabetes Care. 2010;33:1413-8 pubmed publisher
    ....
  19. Turcot V, Bouchard L, Faucher G, Tchernof A, Deshaies Y, Perusse L, et al. DPP4 gene DNA methylation in the omentum is associated with its gene expression and plasma lipid profile in severe obesity. Obesity (Silver Spring). 2011;19:388-95 pubmed publisher
    ....
  20. Dorn J, Harbeck N, Kates R, Gkazepis A, Scorilas A, Soosaipillai A, et al. Impact of expression differences of kallikrein-related peptidases and of uPA and PAI-1 between primary tumor and omentum metastasis in advanced ovarian cancer. Ann Oncol. 2011;22:877-83 pubmed publisher
    ..The changes in levels of these factors from primary tumor to omentum metastasis ('level differentials') could thus be associated with metastastic processes.
  21. De Brabandere K, Jacobs Tulleneers Thevissen D, Czapla J, La Meir M, Delvaux G, Wellens F. Negative-pressure wound therapy and laparoscopic omentoplasty for deep sternal wound infections after median sternotomy. Tex Heart Inst J. 2012;39:367-71 pubmed
    ..broad-spectrum antibiotics, negative-pressure wound therapy, omentoplasty with laparoscopically harvested omentum, and the use of bilateral pectoral muscle advancement flaps...
  22. Pancholi N, Patel J, Gudehithlu K, Kraus M, Dunea G, Arruda J, et al. Culture of omentum-induced regenerating liver yielded hepatocyte-committed stem cells. Transl Res. 2010;156:358-68 pubmed publisher
    Earlier we showed that when omentum, activated by inert particles, is allowed to fuse to a wedge cut in the liver, it induces stem cell proliferation in the liver resulting in massive liver regeneration...
  23. Danner B, Zenker D, Didilis V, Grossmann M, Stojanovic T, Seipelt R, et al. Transposition of greater omentum in deep sternal wound infection caused by methicillin-resistant Staphylococci, with differing clinical course for MRSA and MRSE. Thorac Cardiovasc Surg. 2011;59:21-4 pubmed publisher
    ..Methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus epidermidis (MRSE) are an increasing problem in deep sternal wound infections (DSWI) after cardiac surgery...
  24. Mohammadi R, Azizi S, Delirezh N, Hobbenaghi R, Amini K. Comparison of beneficial effects of undifferentiated cultured bone marrow stromal cells and omental adipose-derived nucleated cell fractions on sciatic nerve regeneration. Muscle Nerve. 2011;43:157-63 pubmed publisher
    ..This approach is clinically translatable toward new methods for enhanced peripheral nerve repair without the limitations of BMSC...
  25. Chandra A, Srivastava R, Kashyap M, Kumar R, Srivastava R, Pant A. The anti-inflammatory and antibacterial basis of human omental defense: selective expression of cytokines and antimicrobial peptides. PLoS ONE. 2011;6:e20446 pubmed publisher
    The wound healing properties of the human omentum are well known and have extensively been exploited clinically. However, the underlying mechanisms of these effects are not well understood...
  26. Tani M, Kawai M, Hirono S, Hatori T, Imaizumi T, Nakao A, et al. Use of omentum or falciform ligament does not decrease complications after pancreaticoduodenectomy: nationwide survey of the Japanese Society of Pancreatic Surgery. Surgery. 2012;151:183-91 pubmed publisher
    Wrapping is thought to prevent pancreatic fistula and postoperative hemorrhage for pancreaticoduodenectomy (PD), and we analyzed whether omentum/falciform ligament wrapping decreases postoperative complications after PD.
  27. Giridhar P, Funk H, Gallo C, Porollo A, Mercer C, Plas D, et al. Interleukin-6 receptor enhances early colonization of the murine omentum by upregulation of a mannose family receptor, LY75, in ovarian tumor cells. Clin Exp Metastasis. 2011;28:887-97 pubmed publisher
    One of the earliest metastatic events in human ovarian cancer, tumor spread to the omentum, may be influenced by expression of interleukin 6 (IL6) and its cognate receptor (IL6Rα)...
  28. Mimatsu K, Oida T, Kano H, Kawasaki A, Fukino N, Kida K, et al. Protection of major vessels and pancreaticogastrostomy using the falciform ligament and greater omentum for preventing pancreatic fistula in soft pancreatic texture after pancreaticoduodenectomy. Hepatogastroenterology. 2011;58:1782-6 pubmed publisher
    ..The aim of this study was to describe an operative technique to protect the vessels and anastomotic site by wrapping them with the falciform ligament and the greater omentum.
  29. Hlebowicz J, Hansson J, Lindstedt S. Microvascular blood flow response in the intestinal wall and the omentum during negative wound pressure therapy of the open abdomen. Int J Colorectal Dis. 2012;27:397-403 pubmed publisher
    ..However, the method has occasionally been associated with increased development of intestinal fistulae. The present study measures microvascular blood flow in the intestinal wall and the omentum before and during NPWT.
  30. Athanassiadi K, Theakos N, Benakis G, Kakaris S, Skottis I. Omental transposition: the final solution for major sternal wound infection. Asian Cardiovasc Thorac Ann. 2007;15:200-3 pubmed
    ..Radical debridement along with omental flap transposition provides definitive control of the infection in cases of failure of other semi-conservative or surgical interventions. Prognosis depends on the general condition of the patient...
  31. Lynch L, O Shea D, Winter D, Geoghegan J, Doherty D, O Farrelly C. Invariant NKT cells and CD1d(+) cells amass in human omentum and are depleted in patients with cancer and obesity. Eur J Immunol. 2009;39:1893-901 pubmed publisher
    ..Here we describe an accumulation of functional iNKT cells in human omentum, a migratory organ with healing properties...
  32. dos Santos Costa S, Blotta R, Mariano M, Meurer L, Edelweiss M. Aesthetic improvements in Poland's syndrome treatment with omentum flap. Aesthetic Plast Surg. 2010;34:634-9 pubmed publisher
    ..This study aimed to demonstrate the superior results of laparoscopically harvested omentum flap to achieve these aesthetic improvements.
  33. Shin M, Lee O, Ha C, Min H, Kim T. Malignant mesothelioma of the greater omentum mimicking omental infarction: a case report. World J Gastroenterol. 2009;15:4856-9 pubmed
    ..We report a rare case of primary malignant mesothelioma of the greater omentum, which mimicked omental infarct...
  34. Khan S, Funk H, Thiolloy S, Lotan T, Hickson J, Prins G, et al. In vitro metastatic colonization of human ovarian cancer cells to the omentum. Clin Exp Metastasis. 2010;27:185-96 pubmed publisher
    Despite the potentially crucial contributions of the omentum in the regulation of ovarian cancer metastatic growth, it remains a poorly understood organ...
  35. Kaiser A, Kang J, Tolazzi A, Sherrod A, Beart R. Primary solitary extragastrointestinal stromal tumor of the greater omentum coexisting with ulcerative colitis. Dig Dis Sci. 2006;51:1850-2 pubmed
  36. Poujade O, Ghiles E, Senasli A. Primary torsion of the greater omentum: case report--review of literature: diagnosis cannot always be performed before surgery. Surg Laparosc Endosc Percutan Tech. 2007;17:54-5 pubmed
    The torsion of greater omentum is a rare cause of acute abdominal pain. After relating a case of torsion of the great omentum we review the literature. Its etiology is uncertain, although several factors have been underlined...
  37. Zagouri F, Papaefthimiou M, Chalazonitis A, Antoniou N, Dimopoulos M, Bamias A. Prostate cancer with metastasis to the omentum and massive ascites: a rare manifestation of a common disease. Onkologie. 2009;32:758-61 pubmed publisher
    ..The lack of skeletal involvement does not exclude the possibility of distant metastases. The presence of ascites may indicate peritoneal disease which could be responsive to current standard chemotherapy. ..
  38. Collins D, Hogan A, O Shea D, Winter D. The omentum: anatomical, metabolic, and surgical aspects. J Gastrointest Surg. 2009;13:1138-46 pubmed publisher
    The omentum is acknowledged to have diverse functions in the pathophysiology of intra-abdominal disease. Its angiogenic properties act as a natural defense mechanism in peritonitis and intra-abdominal sepsis...
  39. Singh A, Pancholi N, Patel J, Litbarg N, Gudehithlu K, Sethupathi P, et al. Omentum facilitates liver regeneration. World J Gastroenterol. 2009;15:1057-64 pubmed
    To investigate the mechanism of liver regeneration induced by fusing the omentum to a small traumatic injury created in the liver. We studied three groups of rats...
  40. van der Windt D, Echeverri G, Ijzermans J, Cooper D. The choice of anatomical site for islet transplantation. Cell Transplant. 2008;17:1005-14 pubmed
    ..However, other sites, such as the omentum, offer drainage of produced insulin into the portal vein for direct utilization in the liver...
  41. Ferron G, Garrido I, Martel P, Gesson Paute A, Classe J, Letourneur B, et al. Combined laparoscopically harvested omental flap with meshed skin grafts and vacuum-assisted closure for reconstruction of complex chest wall defects. Ann Plast Surg. 2007;58:150-5 pubmed
    ..Our aim was to evaluate the use of vacuum-assisted closure (V.A.C.) in combination with laparoscopically harvested omental flap and meshed skin graft for treating these complex wounds...
  42. Moreschi A, Macedo Neto A, Barbosa G, Saueressig M. Aggressive treatment using muscle flaps or omentopexy in infections of the sternum and anterior mediastinum following sternotomy. J Bras Pneumol. 2008;34:654-60 pubmed
    ..To evaluate the impact of an aggressive treatment approach using muscle flaps or omentopexy in infections of the sternum and anterior mediastinum following sternotomy on mortality, as compared to that of a conservative treatment approach...
  43. Csendes A, Maluenda F, Burgos A. A prospective randomized study comparing patients with morbid obesity submitted to laparotomic gastric bypass with or without omentectomy. Obes Surg. 2009;19:490-4 pubmed publisher
    Visceral fat, especially the greater omentum, seems to be an important factor in the development of some metabolic disturbances such as insulin resistance, hyperglycemia, and dyslipidemia...
  44. Yoon S, Lee Y, Yoon K, Kim E, Choi S, Juhng S, et al. Complicated giant diverticulum of the transverse colon accompanied by right inguinal hernia of the greater omentum. Br J Radiol. 2007;80:e201-4 pubmed
    ..We report a case of a complicated giant diverticulum of the transverse colon accompanied by a right inguinal hernia of the greater omentum in a 52-year-old man, as demonstrated on CT.
  45. Singh A, Patel J, Litbarg N, Gudehithlu K, Sethupathi P, Arruda J, et al. Stromal cells cultured from omentum express pluripotent markers, produce high amounts of VEGF, and engraft to injured sites. Cell Tissue Res. 2008;332:81-8 pubmed publisher
    When rat omentum becomes activated by intraperitoneal injection of inert polydextran particles, these particles are rapidly surrounded by cells that express markers of adult stem cells (SDF-1alpha, CXCR4, WT-1) and of embryonic ..
  46. Kobayashi T, Aomatsu Y, Iwata H, Kin T, Kanehiro H, Hisanga M, et al. Survival of microencapsulated islets at 400 days posttransplantation in the omental pouch of NOD mice. Cell Transplant. 2006;15:359-65 pubmed
    ..These results demonstrate the long-term durability of agarose microcapsules against autoimmunity in a syngeneic islet transplantation model in NOD mice. ..
  47. Berberich S, Dähne S, Schippers A, Peters T, Muller W, Kremmer E, et al. Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots. J Immunol. 2008;180:2196-203 pubmed
    ..In this study, we analyze the role of integrins as well as the role of the omentum for B2 cell migration into and out of the peritoneal cavity of mice...
  48. Yeh C, Chuang W, Chou H, Jung S, Hsueh S. Multiple extragenital adenomatoid tumors in the mesocolon and omentum. APMIS. 2008;116:1016-9 pubmed publisher
    ..Here we report another case of multiple extragenital adenomatoid tumors involving the mesocolon and omentum. A 47-year-old woman presented with a delayed menstrual period...
  49. Baumert H, Simon P, Hekmati M, Fromont G, Levy M, Balaton A, et al. Development of a seeded scaffold in the great omentum: feasibility of an in vivo bioreactor for bladder tissue engineering. Eur Urol. 2007;52:884-90 pubmed
    ..We describe a model using the omentum as an in vivo bioreactor for a previously seeded scaffold...
  50. Fain J, Buehrer B, Tichansky D, Madan A. Regulation of adiponectin release and demonstration of adiponectin mRNA as well as release by the non-fat cells of human omental adipose tissue. Int J Obes (Lond). 2008;32:429-35 pubmed
    ..While leptin is only released by mature adipocytes, adiponectin is released by both the non-fat cells and the fat cells derived from human omental adipose tissue. ..
  51. Cancello R, Tordjman J, Poitou C, Guilhem G, Bouillot J, Hugol D, et al. Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity. Diabetes. 2006;55:1554-61 pubmed
    ..These data suggest that the presence of macrophages in omental WAT participates in the cellular mechanisms favoring hepatic fibroinflammatory lesions in obese patients. ..
  52. Tordjman J, Poitou C, Hugol D, Bouillot J, Basdevant A, Bedossa P, et al. Association between omental adipose tissue macrophages and liver histopathology in morbid obesity: influence of glycemic status. J Hepatol. 2009;51:354-62 pubmed publisher
    ..05 vs. low scores). Macrophage accumulation in omental adipose tissue is associated with aggravated steatosis and fibro-inflammation in insulin-resistant obese subjects independently of altered glycemic status. ..
  53. Dvir T, Kedem A, Ruvinov E, Levy O, Freeman I, Landa N, et al. Prevascularization of cardiac patch on the omentum improves its therapeutic outcome. Proc Natl Acad Sci U S A. 2009;106:14990-5 pubmed publisher
    ..a strategy for the engineering of a cardiac patch with mature vasculature by heterotopic transplantation onto the omentum. The patch was constructed by seeding neonatal cardiac cells with a mixture of prosurvival and angiogenic factors ..
  54. Tchkonia T, Giorgadze N, Pirtskhalava T, Thomou T, DePonte M, Koo A, et al. Fat depot-specific characteristics are retained in strains derived from single human preadipocytes. Diabetes. 2006;55:2571-8 pubmed
    ....
  55. Maury E, Ehala Aleksejev K, Guiot Y, Detry R, Vandenhooft A, Brichard S. Adipokines oversecreted by omental adipose tissue in human obesity. Am J Physiol Endocrinol Metab. 2007;293:E656-65 pubmed
    ..In conclusion, six adipokines were newly identified as oversecreted by OAT in obesity. These adipokines may link obesity to its cardiovascular or metabolic comorbidities. ..
  56. MacLaren R, Cui W, Simard S, Cianflone K. Influence of obesity and insulin sensitivity on insulin signaling genes in human omental and subcutaneous adipose tissue. J Lipid Res. 2008;49:308-23 pubmed
    ..05). Together, microarray and real-time PCR data demonstrate that insulin resistance rather than obesity is associated with altered gene expression of insulin signaling genes, especially in OM adipose tissue. ..
  57. Bassols J, Ortega F, Moreno Navarrete J, Peral B, Ricart W, Fernandez Real J. Study of the proinflammatory role of human differentiated omental adipocytes. J Cell Biochem. 2009;107:1107-17 pubmed publisher
    ....
  58. Saifzadeh S, Pourreza B, Hobbenaghi R, Naghadeh B, Kazemi S. Autogenous greater omentum, as a free nonvascularized graft, enhances bone healing: an experimental nonunion model. J Invest Surg. 2009;22:129-37 pubmed publisher
    ..We have investigated the potentiality of autogenous free nonvascularized greater omentum to stimulate the formation of bone in an experimental hypertrophic nonunion model...
  59. Zaha H, Inamine S, Naito T, Nomura H. Laparoscopically harvested omental flap for immediate breast reconstruction. Am J Surg. 2006;192:556-8 pubmed
    ..Breast cancer surgery and accompanying breast reconstruction have been diversified. We report our experience of immediate breast reconstruction using laparoscopically harvested omental flap (LHOF)...
  60. Eifert S, Kronschnabl S, Kaczmarek I, Reichart B, Vicol C. Omental flap for recurrent deep sternal wound infection and mediastinitis after cardiac surgery. Thorac Cardiovasc Surg. 2007;55:371-4 pubmed
    ..Unsuccessful surgical treatment of deep sternal wound infection (DSWI) and mediastinitis may lead to sepsis, multiorgan failure and death. Omental flap transposition (OFT) may, in this situation, be the only effective therapy...
  61. Chuwa E, Seow Choen F. Omentum as a cover for abdominal wall loss. Tech Coloproctol. 2006;10:139-42 pubmed
    ..The presence of ample omentum helped prevent evisceration and allowed granulation tissue to gradually seal the abdominal cavity over a period ..
  62. Karabulut B, Sonmez K, Turkyilmaz Z, Demirogullari B, Karabulut R, Sezer C, et al. Omentum prevents intestinal adhesions to mesh graft in abdominal infections and serosal defects. Surg Endosc. 2006;20:978-82 pubmed
    ..In this study, the effects resulting from the presence or absence of the omentum were evaluated in the setting of infection or serosal defects in the formation of adhesions in abdominal closures ..
  63. van Beek E, Bakker A, Kruyt P, Hofker M, Saris W, Keijer J. Intra- and interindividual variation in gene expression in human adipose tissue. Pflugers Arch. 2007;453:851-61 pubmed
    ....
  64. Gerber S, Rybalko V, Bigelow C, Lugade A, Foster T, Frelinger J, et al. Preferential attachment of peritoneal tumor metastases to omental immune aggregates and possible role of a unique vascular microenvironment in metastatic survival and growth. Am J Pathol. 2006;169:1739-52 pubmed
    ..Using five different tumor cell lines in three different strains of mice, we found that the omentum was a major site of metastases growth for intraperitoneal tumors...
  65. Patriti A, Rondelli F, Gullà N, Donini A. Laparoscopic treatment of a solitary fibrous tumor of the greater omentum presenting as spontaneous haemoperitoneum. Ann Ital Chir. 2006;77:351-3 pubmed
    ..The patient underwent laparoscopy that revealed a bleeding mass of the great omentum. Laparoscopic stapled resection of the greater omentum was carried out...
  66. Jani K, Saxena A, Vaghasia R. Omental plugging for large-sized duodenal peptic perforations: A prospective randomized study of 100 patients. South Med J. 2006;99:467-71 pubmed
    ..Due to friable margins and the moribund state of the patient, managing giant duodenal perforations (>20 mm in diameter) is a challenging task...
  67. Palming J, Gabrielsson B, Jennische E, Smith U, Carlsson B, Carlsson L, et al. Plasma cells and Fc receptors in human adipose tissue--lipogenic and anti-inflammatory effects of immunoglobulins on adipocytes. Biochem Biophys Res Commun. 2006;343:43-8 pubmed
    ..05), but did not influence lipolysis. In conclusion, immunoglobulins produced by plasma cells in human adipose tissue could influence adipocyte metabolism and cytokine production...
  68. Reza Mousavi S, Khoshnevis J, Kharazm P. Surgical treatment of hydatid cyst of the liver: drainage versus omentoplasty. Ann Hepatol. 2005;4:272-4 pubmed
    ..Liver is the most common site of infection and several methods of surgery have been described to treat this common disease. In this study we aim to compare the results of two common methods of surgery; simple drainage versus omentoplasty...
  69. Bender T, Riesenhuber A, Endemann M, Herkner K, Witowski J, Jorres A, et al. Correlation between HSP-72 expression and IL-8 secretion in human mesothelial cells. Int J Artif Organs. 2007;30:199-203 pubmed
    ..In this study, we correlated induction of HSP-72, as a marker of the cellular stress response, to secretion of IL-8, as a marker for pro-inflammatory cytokines, in mesothelial cells upon sublethal PDF exposure...
  70. Shiba H, Misawa T, Kobayashi S, Yokota T, Son K, Yanaga K. Hemangiopericytoma of the greater omentum. J Gastrointest Surg. 2007;11:549-51 pubmed
    ..Excision of the tumor in the greater omentum and cholecystectomy were performed laparoscopically...
  71. Madani R, Karastergiou K, Ogston N, Miheisi N, Bhome R, Haloob N, et al. RANTES release by human adipose tissue in vivo and evidence for depot-specific differences. Am J Physiol Endocrinol Metab. 2009;296:E1262-8 pubmed publisher
    ..While it appears unlikely that the adipose organ contributes significantly to circulating levels, local implications of this chemokine deserve further investigation...
  72. Berman D, O Neil J, Coffey L, Chaffanjon P, Kenyon N, Ruiz P, et al. Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold. Am J Transplant. 2009;9:91-104 pubmed publisher
    ..Our results suggest this extrahepatic transplantation site has potential as an alternative site for clinical islet cell transplantation...
  73. Liang Y, Xu X, Wang H, Wang P. [Correlation between the expression of gastrocolic omentum visfatin mRNA and gestational diabetes mellitus]. Zhonghua Fu Chan Ke Za Zhi. 2008;43:824-7 pubmed
    To investigate the relationship between different expression of gastrocolic omentum visfatin(VF) mRNA and gestational diabetes mellitus (GDM) in late trimester pregnancy.
  74. Maternini M, Pezzetta E, Martinet O. Laparoscopic approach for idiopathic segmental infarction of the greater omentum. Minerva Chir. 2009;64:225-7 pubmed
    Idiopathic segmental infarction of the greater omentum is an uncommon condition that should be considered in the differential diagnosis of right-side abdominal pain...
  75. Rangel Moreno J, Moyron Quiroz J, Carragher D, Kusser K, Hartson L, Moquin A, et al. Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens. Immunity. 2009;30:731-43 pubmed publisher
    The omentum is a site of B1 cell lymphopoiesis and immune responsiveness to T cell-independent antigens. However, it is unknown whether it supports immune responses independently of conventional lymphoid organs...
  76. Que Y, Wang X, Liu Y, Li P, Ou G, Zhao W. Ultrasound-guided biopsy of greater omentum: an effective method to trace the origin of unclear ascites. Eur J Radiol. 2009;70:331-5 pubmed publisher
    Thickened greater omentum is encountered with high frequency in patients with ascites...
  77. Paslakis G, Keuneke C, Groene H, Schroppel B, Schmid H, Schloendorff D. The putative role of human peritoneal adipocytes in the fight against bacteria: synthesis of the antimicrobial active peptide DEFA1-3. Nephron Exp Nephrol. 2010;115:e96-100 pubmed publisher
    ..As defensins are natural antimicrobial peptides, we hypothesized that adipocytes as the major constituents of the omentum could play an important role in protecting against infection by generating defensin (DEFA1-3).
  78. Zivanovic O, Sima C, Iasonos A, Hoskins W, Pingle P, Leitao M, et al. The effect of primary cytoreduction on outcomes of patients with FIGO stage IIIC ovarian cancer stratified by the initial tumor burden in the upper abdomen cephalad to the greater omentum. Gynecol Oncol. 2010;116:351-7 pubmed publisher
    ..survival (PFS) and overall survival (OS) of patients with advanced ovarian carcinoma stratified by the initial presence and volume of upper abdominal disease cephalad to the greater omentum (UAD) found at the time of exploration.
  79. García Gómez I, Goldsmith H, Angulo J, Prados A, López Hervás P, Cuevas B, et al. Angiogenic capacity of human omental stem cells. Neurol Res. 2005;27:807-11 pubmed
    The goals of the present study are to obtain, expand and characterize a stem cell population from human omentum and to evaluate its in vivo angiogenic capacities.
  80. Doig T, Monaghan H. Sampling the omentum in ovarian neoplasia: when one block is enough. Int J Gynecol Cancer. 2006;16:36-40 pubmed
    ..Unlike the primary ovarian lesion, no guidelines exist as to how the pathologist should sample the omentum. We retrospectively examined pathology reports from 692 cases of primary ovarian neoplasia and demonstrated a ..
  81. Franzini C, Alessandri L, Piscioli I, Donato S, Faraci R, Morelli L, et al. Extra-gastrointestinal stromal tumor of the greater omentum: report of a case and review of the literature. World J Surg Oncol. 2008;6:25 pubmed publisher
    ..Extra-gastrointestinal stromal tumors (EGISTs) are neoplasms with overlapping immunohistological features, occurring in the abdomen outside the gastrointestinal tract with no connection to the gastric or intestinal wall...
  82. Costi R, Cecchini S, Randone B, Violi V, Roncoroni L, Sarli L. Laparoscopic diagnosis and treatment of primary torsion of the greater omentum. Surg Laparosc Endosc Percutan Tech. 2008;18:102-5 pubmed publisher
    Clinical presentation of primary torsion of the greater omentum is nonspecific, thus rarely allowing for a preoperative diagnosis. Three patients presented with acute but nonspecific abdominal symptoms...
  83. Koshariya M, Jagad R, Kawamoto J, Papastratis P, Sharma S, Kefalourous H, et al. Gastrointestinal stromal tumor of gastrohepatic omentum in a patient with von Recklinghausen's disease (neurofibromatosis type 1). Hepatogastroenterology. 2007;54:2230-1 pubmed
    It is very rare to find large gastrointestinal stromal tumors arising from the gastrohepatic omentum in a patient with neurofibromatosis type 1...
  84. Litbarg N, Gudehithlu K, Sethupathi P, Arruda J, Dunea G, Singh A. Activated omentum becomes rich in factors that promote healing and tissue regeneration. Cell Tissue Res. 2007;328:487-97 pubmed
    ..healing when applied to an injured site, we injected a foreign body into the abdominal cavity to activate the omentum. One week after the injection, we isolated the omentum and measured blood vessel density, blood content, growth ..
  85. Costa S, Blotta R, Mariano M, Meurer L, Edelweiss M. Laparoscopic treatment of Poland's syndrome using the omentum flap technique. Clinics (Sao Paulo). 2010;65:401-6 pubmed publisher
    ..This study aims to demonstrate that superior aesthetic results can be achieved by using a laparoscopically harvested omentum flap to treat this condition.
  86. Baviskar B, Dongre S, Karle R, Sewlikar V. Teratoma of lesser omentum in a male infant. J Postgrad Med. 2006;52:304-5 pubmed
  87. Aslan H, Altunkaynak B, Altunkaynak M, Vuraler O, Kaplan S, Unal B. Effect of a high fat diet on quantitative features of adipocytes in the omentum: an experimental, stereological and ultrastructural study. Obes Surg. 2006;16:1526-34 pubmed
    ..To our knowledge, there is no stereological study on numerical density, nuclear height and volume of adipocytes in omental adipose tissue in the female rat fed a HF diet in the literature...
  88. Fabbrini E, TAMBOLI R, Magkos F, Marks Shulman P, Eckhauser A, Richards W, et al. Surgical removal of omental fat does not improve insulin sensitivity and cardiovascular risk factors in obese adults. Gastroenterology. 2010;139:448-55 pubmed publisher
    ..Therefore, a reduction in VAT is considered an important target of obesity therapy. We evaluated whether reducing VAT mass by surgical removal of the omentum improves insulin sensitivity and metabolic function in obese patients.
  89. Sharifiaghdas F, Hamzehiesfahani N, Moghadasali R, Ghaemimanesh F, Baharvand H. Human amniotic membrane as a suitable matrix for growth of mouse urothelial cells in comparison with human peritoneal and omentum membranes. Urol J. 2007;4:71-8 pubmed
    ..The aim of the present study was to assess the proliferation quality of mouse urothelial cells on 3 natural matrixes of human amniotic membrane (AM), peritoneum, and omentum, and to compare them with collagen matrix.
  90. Harman Boehm I, Bluher M, Redel H, Sion Vardy N, Ovadia S, Avinoach E, et al. Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity. J Clin Endocrinol Metab. 2007;92:2240-7 pubmed
    ..Macrophage infiltration into adipose tissue has been demonstrated to accompany obesity, with a potential preferential infiltration into intraabdominal vs. sc fat...
  91. Todoroki T, Sano T, Sakurai S, Segawa A, Saitoh T, Fujikawa K, et al. Primary omental gastrointestinal stromal tumor (GIST). World J Surg Oncol. 2007;5:66 pubmed
    ..We report herein a rare case of primary omental gastrointestinal stromal tumor (GIST)...