Treponema

Summary

Alias: "Microspironema" Stiles and Pfender 1905, "Spironema" Vuillemin 1905, Microspironema, Treponema Schaudinn 1905

Top Publications

  1. Velsko I, Chukkapalli S, Rivera Kweh M, Zheng D, Aukhil I, Lucas A, et al. Periodontal pathogens invade gingiva and aortic adventitia and elicit inflammasome activation in αvβ6 integrin-deficient mice. Infect Immun. 2015;83:4582-93 pubmed publisher
    ..We investigated the ability of a polymicrobial consortium of Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, and Fusobacterium nucleatum to colonize the periodontium and induce local and ..
  2. Calvet G, Aguiar R, Melo A, Sampaio S, de Filippis I, Fabri A, et al. Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study. Lancet Infect Dis. 2016;16:653-660 pubmed publisher
    ..dengue virus, chikungunya virus, Toxoplasma gondii, rubella virus, cytomegalovirus, herpes simplex virus, HIV, Treponema pallidum, and parvovirus B19 were all negative...
  3. Zhang R, Qian J, Wang Z, Yuan Y. [Ocular manifestations of syphilitic uveoretinitis in patients co-infected with human immunodeficiency virus]. Zhonghua Yan Ke Za Zhi. 2015;51:739-45 pubmed
    ..Patients were selected with positive serologic tests, including rapid plasma regain titer (RPR) > 1:8, treponema pallidum particle agglutination assay (TPPA) and human immunodeficiency virus (HIV)...
  4. Mali S, Mitchell M, Havis S, Bodunrin A, Rangel J, Olson G, et al. A Proteomic Signature of Dormancy in the Actinobacterium Micrococcus luteus. J Bacteriol. 2017;199: pubmed publisher
    ..state in which diverse bacteria, including Mycobacterium tuberculosis, Staphylococcus aureus, Treponema pallidum (syphilis), and Borrelia burgdorferi (Lyme disease), curtail metabolic activity to survive ..
  5. Ran S, Liu B, Gu S, Sun Z, Liang J. Analysis of the expression of NLRP3 and AIM2 in periapical lesions with apical periodontitis and microbial analysis outside the apical segment of teeth. Arch Oral Biol. 2017;78:39-47 pubmed publisher
    ..4%), Tannerella forsythia (19/47, 40.4%), Actinomyces sp. (17/47, 36.17%), Treponema denticola (10/47,21.28%), Actinomyces israelii (9/47,19.15%), Prevotella intermedia (6/47, 12...
  6. Mahendra J, Mahendra L, Nagarajan A, Mathew K. Prevalence of eight putative periodontal pathogens in atherosclerotic plaque of coronary artery disease patients and comparing them with noncardiac subjects: A case-control study. Indian J Dent Res. 2015;26:189-95 pubmed publisher
    ..f), Campylobacter rectus (C.r), Eikenella corrodens (E.c), Porphyromonas gingivalis (P.g), Treponema denticola (T.d), Prevotella nigrescens (P.n) ,Aggregatibacter actinomycetemcomitans (A.a), P...
  7. Chukkapalli S, Rivera Kweh M, Gehlot P, Velsko I, Bhattacharyya I, Calise S, et al. Periodontal bacterial colonization in synovial tissues exacerbates collagen-induced arthritis in B10.RIII mice. Arthritis Res Ther. 2016;18:161 pubmed publisher
    ..CIA-prone B10.RIII mice were infected orally with a polybacterial mixture of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia for 24 weeks before induction of CIA...
  8. Birsan I. Polymerase chain reaction as a prospect for the early diagnosis and prediction of periodontal diseases in adolescents. Eur Arch Paediatr Dent. 2015;16:9-12 pubmed publisher
    ..i), Tannerella forsythia (T.f) [Bacteroides forsythus], Treponema denticola (T.d), Actinobacillus actinomycetemcomitans (A.a), Porphyromonas gingivalis (P...
  9. Gaydos C, Rizzo Price P, Balakrishnan P, Mateta P, Leon S, Verevochkin S, et al. Impact of international laboratory partnerships on the performance of HIV/sexually transmitted infection testing in five resource-constrained countries. Int J STD AIDS. 2011;22:645-52 pubmed publisher
    ..assays, herpes simplex virus type 2 enzyme immunoassay (EIA), syphilis serology (rapid plasma regain and Treponema pallidum particle agglutination assay, HIV serology (EIA/Western blot) and Trichomonas vaginalis culture...

More Information

Publications215 found, 100 shown here

  1. Neering S, Adyani Fard S, Klocke A, Rüttermann S, Flemmig T, Beikler T. Periodontitis associated with plasminogen deficiency: a case report. BMC Oral Health. 2015;15:59 pubmed publisher
    ..Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, Prevotella intermedia, Prevotella nigrescens and Eikenella corrodens have been detected by realtime ..
  2. Merglova V, Koberova Ivancakova R, Broukal Z, Dort J. The presence of cariogenic and periodontal pathogens in the oral cavity of one-year-old infants delivered pre-term with very low birthweights: a case control study. BMC Oral Health. 2014;14:109 pubmed publisher
    ..Actinomyces spp., Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Peptostreptococcus micros, Prevotella intermedia, Fusobacterium nucleatum) were identified and their ..
  3. Demmer R, Jacobs D, Singh R, Zuk A, Rosenbaum M, Papapanou P, et al. Periodontal Bacteria and Prediabetes Prevalence in ORIGINS: The Oral Infections, Glucose Intolerance, and Insulin Resistance Study. J Dent Res. 2015;94:201S-11S pubmed publisher
    ..species were assessed at baseline, including Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, and Actinomyces naeslundii...
  4. Tatikonda A, Sudheep N, Biswas K, Gowtham K, Pujari S, Singh P. Evaluation of Bacteriological Profile in the Apical Root Segment of the Patients with Primary Apical Periodontitis. J Contemp Dent Pract. 2017;18:44-48 pubmed
    ..species, Streptococcus species, Olsenella uli, Synergistes species, Fusobacterium nucleatum, Parvimonas micra, Treponema denticola, and Filifactor alocis were the specific species detected...
  5. Kang J, Kim D, Choi B, Park J. Inhibition of malodorous gas formation by oral bacteria with cetylpyridinium and zinc chloride. Arch Oral Biol. 2017;84:133-138 pubmed publisher
    ..actinomycetemcomitans, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola, Tannerella forsythia, Staphylococcus aureus and Streptococcus mutans) known to be involved in the ..
  6. Schöfer H. [Male circumcision from an infectiological point of view]. Hautarzt. 2015;66:30-7 pubmed publisher
    ..and the efficacy of circumcision in reducing the risks of sexual transmission of HIV, herpes viruses, HPV, treponema pallidum, chlamydia, hemophilus ducrey and Neisseria gonorrhoeae...
  7. Sánchez Montalvá A, Salvador F, Ruiz Camps I, Barba P, Valcarcel D, Sulleiro E, et al. Imported Disease Screening Prior to Chemotherapy and Bone Marrow Transplantation for Oncohematological Malignancies. Am J Trop Med Hyg. 2016;95:1463-1468 pubmed
    ..Patients were tested for soil-transmitted helminths, hepatitis virus, and human immunodeficiency virus, Treponema pallidum, human T-cell lymphotropic virus, latent tuberculosis infection, Toxoplasma spp...
  8. Liu J, Liu W, Liu Y, Zhou X, Zhang Z, Sun Z. Prevalence of microorganisms co-infections in human papillomaviruses infected women in Northern China. Arch Gynecol Obstet. 2016;293:595-602 pubmed publisher
    ..of serological markers for human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV) and Treponema pallidum infections...
  9. Nenoff P, Manos A, Ehrhard I, Kruger C, Paasch U, Helmbold P, et al. [Nonviral sexually transmitted infections-epidemiology, clinical manifestations, diagnostic workup, therapy : Part 3: Treponemes, Gardnerella and trichomonads]. Hautarzt. 2017;68:136-148 pubmed publisher
    ..The antibiotic agent of choice for treatment of syphilis is still penicillin. There are no penicillin-resistant Treponema pallidum strains. Alternatives are ceftriaxone and doxycycline...
  10. Chukkapalli S, Velsko I, Rivera Kweh M, Larjava H, Lucas A, Kesavalu L. Global TLR2 and 4 deficiency in mice impacts bone resorption, inflammatory markers and atherosclerosis to polymicrobial infection. Mol Oral Microbiol. 2017;32:211-225 pubmed publisher
    ..and TLR4-/- mice to polymicrobial infection with periodontal pathogens Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, and Fusobacterium nucleatum...
  11. Barnabas S, Dabee S, Passmore J, Jaspan H, Lewis D, Jaumdally S, et al. Converging epidemics of sexually transmitted infections and bacterial vaginosis in southern African female adolescents at risk of HIV. Int J STD AIDS. 2017;:956462417740487 pubmed publisher
    ..Neisseria gonorrhoeae, Trichomonas vaginalis, Mycoplasma genitalium, herpes simplex virus (HSV)-1, HSV-2, Treponema pallidum, and Haemophilus ducreyi) were detected by multiplex polymerase chain reaction, human papillomavirus (..
  12. Chen S, Zhang X, Chen Z, Wang W, Li Y, Li C, et al. Mutual blood donation is safer at small blood collection stations in China. Transfus Apher Sci. 2015;53:315-9 pubmed publisher
    ..HBsAg), antibodies against hepatitis C virus (anti-HCV), human immunodeficiency virus (anti-HIV) (1 + 2) and Treponema pallidum (anti-TP) by the enzyme immunoassays (EIAs), and alanine aminotransferase (ALT) in the Center Blood ..
  13. Benvenga S, Guarneri F. Molecular mimicry and autoimmune thyroid disease. Rev Endocr Metab Disord. 2016;17:485-498 pubmed publisher
    ..potential pathogenic importance of Toxoplasma gondii, some Bifidobacteria and Lactobacilli, Candida albicans, Treponema pallidum and hepatitis C virus in autoimmune thyroid disease, indicating specific molecular targets for future ..
  14. Moreira Soto A, Cabral R, Pedroso C, Eschbach Bludau M, Rockstroh A, Vargas L, et al. Exhaustive TORCH Pathogen Diagnostics Corroborate Zika Virus Etiology of Congenital Malformations in Northeastern Brazil. mSphere. 2018;3: pubmed publisher
    ..exposure to ZIKV, Chikungunya virus (CHIKV), dengue virus, and 8 established TORCH (Toxoplasma gondii, Treponema pallidum, rubella virus, cytomegalovirus, herpes simplex virus 1 [HSV-1] and HSV-2, varicella-zoster virus, ..
  15. Gimenes F, Souza R, Bento J, Teixeira J, Maria Engler S, Bonini M, et al. Male infertility: a public health issue caused by sexually transmitted pathogens. Nat Rev Urol. 2014;11:672-87 pubmed publisher
    ..b>Treponema pallidum and Trichomonas vaginalis, because few studies have evaluated the influence of these pathogens on male ..
  16. Chukkapalli S, Velsko I, Rivera Kweh M, Zheng D, Lucas A, Kesavalu L. Polymicrobial Oral Infection with Four Periodontal Bacteria Orchestrates a Distinct Inflammatory Response and Atherosclerosis in ApoE null Mice. PLoS ONE. 2015;10:e0143291 pubmed publisher
    ..mice with a polybacterial consortium of 4 well-characterized periodontal pathogens, Porphyromonas gingivalis, Treponema denticola, Tannerealla forsythia and Fusobacterium nucleatum, that have been identified in human atherosclerotic ..
  17. Lobo A, Gao Y, Rusie L, Houlberg M, Mehta S. Association between eye diagnosis and positive syphilis test results in a large, urban sexually transmitted infection/primary care clinic population. Int J STD AIDS. 2017;:956462417726700 pubmed publisher
    ..immunoassay [EIA], rapid plasma reagin [RPR] titer, fluorescent treponemal antibody absorption [FTA-Abs], Treponema pallidum Ab)...
  18. Sparks Stein P, Steffen M, Smith C, Jicha G, Ebersole J, Abner E, et al. Serum antibodies to periodontal pathogens are a risk factor for Alzheimer's disease. Alzheimers Dement. 2012;8:196-203 pubmed publisher
    ..periodontitis, including Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Campylobacter rectus, Treponema denticola, Fusobacterium nucleatum, Tannerella forsythia, and Prevotella intermedia...
  19. Huang Y, Zeng J, Chen G, Xie X, Guo W, Tian W. Periodontitis contributes to adipose tissue inflammation through the NF-<kappa>B, JNK and ERK pathways to promote insulin resistance in a rat model. Microbes Infect. 2016;18:804-812 pubmed publisher
    ..model was induced by ligatures and injection of "red complex", which consisted of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia, for two weeks...
  20. Schmalz G, Berisha L, Wendorff H, Widmer F, Marcinkowski A, Teschler H, et al. Association of time under immunosuppression and different immunosuppressive medication on periodontal parameters and selected bacteria of patients after solid organ transplantation. Med Oral Patol Oral Cir Bucal. 2018;23:e326-e334 pubmed publisher
    ..The mean PPD and CAL as well as prevalence of Treponema denticola and Capnocytophaga species was shown to be different but heterogeneous depending on time under ..
  21. Park J, Seo Y, Jeong S, Lee J. Prevalence of and Risk Factors for Sexually Transmitted Infections among Korean Adolescents under Probation. J Korean Med Sci. 2017;32:1771-1778 pubmed publisher
    ..Neisseria gonorrhoeae, Trichomonas vaginalis, herpes simplex virus (HSV), human immunodeficiency virus (HIV), Treponema pallidum, Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum, and Ureaplasma parvum...
  22. Tsai M, Yang C, Lee N, Hsieh S, Lin Y, Sun H, et al. Jarisch-Herxheimer reaction among HIV-positive patients with early syphilis: azithromycin versus benzathine penicillin G therapy. J Int AIDS Soc. 2014;17:18993 pubmed publisher
    ..Between 2012 and 2013, polymerase chain reaction (PCR) assay was performed to detect Treponema pallidum DNA in clinical specimens, and PCR restriction fragment length polymorphism of the 23S ribosomal RNA ..
  23. Tiittala P, Ristola M, Liitsola K, Ollgren J, Koponen P, Surcel H, et al. Missed hepatitis b/c or syphilis diagnosis among Kurdish, Russian, and Somali origin migrants in Finland: linking a population-based survey to the national infectious disease register. BMC Infect Dis. 2018;18:137 pubmed publisher
    ..Seroprevalence of hepatitis B surface antigen (HBsAg) was 2.3%, hepatitis C antibodies 1.7%, and Treponema pallidum antibodies 1.3%. No cases of HIV were identified...
  24. Koutouzis T, Eastman C, Chukkapalli S, Larjava H, Kesavalu L. A Novel Rat Model of Polymicrobial Peri-Implantitis: A Preliminary Study. J Periodontol. 2017;88:e32-e41 pubmed publisher
    ..One week after healing of abutments, rats were infected with Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia for 12 weeks...
  25. Lu R, Meng H, Gao X, Xu L, Feng X. Effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis. J Periodontal Res. 2014;49:574-83 pubmed
    ..Porphyromonas gingivalis, Treponema denticola, Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Fusobacterium nucleatum from the ..
  26. Sampedro Martínez A, Padilla Malo A, Gómez Camarasa C, Rodriguez Granger J, Lara Oya A. Evaluation of a new chemiluminescence immunoassay for laboratory diagnosis of syphilis. J Microbiol Methods. 2013;94:133-134 pubmed publisher
    ..was to evaluate diagnostic performances of automated chemiluminescence immunoassay (CLIA) in comparison with Treponema pallidum hemagglutination test (TPHA). The specificity of CLIA was 98.9% and 99...
  27. Jervøe Storm P, Jepsen S, Jöhren P, Mericske Stern R, Enkling N. Internal bacterial colonization of implants: association with peri-implant bone loss. Clin Oral Implants Res. 2015;26:957-963 pubmed publisher
    ..Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola, and Tannerella forsythia as well as total bacterial counts by real-time PCR...
  28. Kargas K, Tsalikis L, Sakellari D, Menexes G, Konstantinidis A. Pilot study on the clinical and microbiological effect of subgingival glycine powder air polishing using a cannula-like jet. Int J Dent Hyg. 2015;13:161-9 pubmed publisher
    ..were analysed using 'checkerboard' DNA-DNA hybridization for Porphyromonas gingivalis, Tannerrella forsythia and Treponema denticola. All groups were homogeneous at baseline for the clinical parameters assessed...
  29. Yamada H, Tairaku S, Morioka I, Sonoyama A, Tanimura K, Deguchi M, et al. Nationwide survey of mother-to-child infections in Japan. J Infect Chemother. 2015;21:161-4 pubmed publisher
    ..infections for 34 cases with cytomegalovirus (CMV), 1 with Toxoplasma gondii, 4 with rubella virus, 5 with Treponema pallidum, 8 with herpes simplex virus, and 69 with parvovirus B19 was confirmed after questionnaire assessment...
  30. Bello L, Mimessi G, Gómez M. [Urticarial syndrome related to Treponema infection]. Rev Alerg Mex. 2014;61:363-7 pubmed
  31. Marks M, Mitjà O, Solomon A, Asiedu K, Mabey D. Yaws. Br Med Bull. 2015;113:91-100 pubmed publisher
    Yaws, caused by Treponema pallidum ssp. pertenue, is endemic in parts of West Africa, Southeast Asia and the Pacific. The WHO has launched a campaign based on mass treatment with azithromycin, to eradicate yaws by 2020...
  32. Yáñez Vico R, Iglesias Linares A, Ballesta Mudarra S, Ortiz Ariza E, Solano Reina E, Perea E. Short-term effect of removal of fixed orthodontic appliances on gingival health and subgingival microbiota: a prospective cohort study. Acta Odontol Scand. 2015;73:496-502 pubmed publisher
    ..Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola were performed...
  33. Terris Prestholt F, Vickerman P, Torres Rueda S, Santesso N, Sweeney S, Mallma P, et al. The cost-effectiveness of 10 antenatal syphilis screening and treatment approaches in Peru, Tanzania, and Zambia. Int J Gynaecol Obstet. 2015;130 Suppl 1:S73-80 pubmed publisher
    ..Rapid syphilis immunochromatographic strip tests detecting only Treponema pallidum antibodies (single RSTs) or both treponemal and non-treponemal antibodies (dual RSTs) are now available...
  34. Simčič S, Potočnik M. Serological diagnosis of syphilis: a comparison of different diagnostic methods. Acta Dermatovenerol Alp Pannonica Adriat. 2015;24:17-20 pubmed
    ..a total of 437 clinical serum samples from adults throughout Slovenia tested with Rapid Plasma Reagin (RPR), Treponema pallidum hemagglutination (TPHA), and an automated chemiluminescence immunoassay (CIA) according to the ..
  35. Ardila C, Guzmán I. Association of Porphyromonas gingivalis with high levels of stress-induced hormone cortisol in chronic periodontitis patients. J Investig Clin Dent. 2016;7:361-367 pubmed publisher
    ..Porphyromonas gingivalis (P. gingivalis) Tannerella forsythia, Treponema denticola, and Aggregatibacter actinomycetemcomitans were detected by polymerase chain reaction using primers ..
  36. Sullivan L, Carter S, Duncan J, Grove White D, Angell J, Evans N. The gastrointestinal tract as a potential infection reservoir of digital dermatitis-associated treponemes in beef cattle and sheep. Appl Environ Microbiol. 2015;81:7460-9 pubmed publisher
    ..It has now been reported in beef cattle and also sheep (contagious ovine digital dermatitis [CODD]). Three Treponema phylogroups are consistently isolated from lesions, Treponema medium-like, Treponema phagedenis-like, and ..
  37. Houston S, Taylor J, Denchev Y, Hof R, Zuerner R, Cameron C. Conservation of the Host-Interacting Proteins Tp0750 and Pallilysin among Treponemes and Restriction of Proteolytic Capacity to Treponema pallidum. Infect Immun. 2015;83:4204-16 pubmed publisher
    The spirochete Treponema pallidum subsp. pallidum is the causative agent of syphilis, a chronic, sexually transmitted infection characterized by multiple symptomatic and asymptomatic stages...
  38. Park B, Yoon J, Rim J, Lee A, Kim H. Comparison of Six Automated Treponema-Specific Antibody Assays. J Clin Microbiol. 2016;54:163-7 pubmed publisher
    Six different Treponema (TP)-specific immunoassays were compared to the fluorescent treponemal antibody absorption (FTA-ABS) test. A total of 615 samples were tested...
  39. Chu C, Chen W, Yeh S, Yeh H, Fang C. Syphilitic orchitis mimicking a testicular tumor in a clinically occult HIV-infected young man: a case report with emphasis on a challenging pathological diagnosis. Diagn Pathol. 2016;11:4 pubmed publisher
    ..Syphilitic orchitis was confirmed by both an immunohistochemical study and PCR testing for the Treponema pallidum DNA polymerase I gene using paraffin-embedded tissues...
  40. Sousa V, Nibali L, Spratt D, Dopico J, Mardas N, Petrie A, et al. Peri-implant and periodontal microbiome diversity in aggressive periodontitis patients: a pilot study. Clin Oral Implants Res. 2017;28:558-570 pubmed publisher
    ..Actinomyces, Porphyromonas, Prevotella, Streptococcus, Actinomycetaceae, TM7-3, Selenomonas, and Dialister, Treponema, Parvimonas and Peptostreptococcus in the TD group...
  41. Jones M, Vanyo S, Visser M. The C-terminal region of the major outer sheath protein of Treponema denticola inhibits neutrophil chemotaxis. Mol Oral Microbiol. 2017;32:375-389 pubmed publisher
    b>Treponema denticola is an oral spirochete strongly associated with severe periodontal disease...
  42. Wang R, Chen M, Feng F, Zhang J, Sui Q, Tong J, et al. Effects of chlortetracycline and copper on tetracyclines and copper resistance genes and microbial community during swine manure anaerobic digestion. Bioresour Technol. 2017;238:57-69 pubmed publisher
    ..Microbial community evolution was the main driver. It was interesting that Treponema might indicate the termination of anaerobic digestion and compete with ARGs host bacteria...
  43. Escobedo Hinojosa W, Pardo Lopez L. Analysis of bacterial metagenomes from the Southwestern Gulf of Mexico for pathogens detection. Pathog Dis. 2017;75: pubmed publisher
    ..Borrelia, Ehrlichia, Leptospira, Mycobacterium, Mycoplasma, Salmonella, Staphylococcus, Streptococcus and Treponema. While there are no previous metagenomics studies of this environment, the potential influences of natural, ..
  44. Reinehr C, Kalil C, Reinehr V. Secondary syphilis: The great imitator can't be forgotten. Rev Assoc Med Bras (1992). 2017;63:481-483 pubmed publisher
    Syphilis is an infection caused by Treponema pallidum, mainly transmitted by sexual contact. Since 2001, primary and secondary syphilis rates started to rise, with an epidemic resurgence...
  45. Strouhal M, Oppelt J, Mikalová L, Arora N, Nieselt K, Gonzalez Candelas F, et al. Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing treponemes. BMC Res Notes. 2018;11:16 pubmed publisher
    b>Treponema pallidum subsp. pallidum (TPA) is the causative agent of syphilis...
  46. Mitjà O, Godornes C, Houinei W, Kapa A, Paru R, Abel H, et al. Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study. Lancet. 2018;391:1599-1607 pubmed publisher
    ..We used genotyping and travel history to identify importation events. Active yaws confirmed by PCR specific for Treponema pallidum was the primary outcome indicator. The study is registered with ClinicalTrials.gov, number NCT01955252...
  47. Gao X, Zhou J, Sun Y, Wang L, Zhou Y. Differential expressions of biomarkers in gingival crevicular fluid of Han and Uygur populations with peri-implantitis. Medicine (Baltimore). 2018;97:e0471 pubmed publisher
    ..dominant subgingival bacteria species of the case groups mainly included Prevotella, clostridium, Porphyromonas, treponema, Streptococcus, neisseria, and hemophilus...
  48. Kumar S, Caimano M, Anand A, Dey A, Hawley K, LeDoyt M, et al. Sequence Variation of Rare Outer Membrane Protein ?-Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp. pallidum, the Syphilis Spirochete. MBio. 2018;9: pubmed publisher
    ..has been made in topologically and functionally characterizing integral outer membrane proteins (OMPs) of Treponema pallidum subspecies pallidum, the syphilis spirochete, and identifying its surface-exposed ?-barrel ..
  49. Liang X, Liu T, Yuan C, Wang W, Liang P. The disappearance of femoral head and neck resulting from extensive bone defect caused by secondary syphilis: a case report and literature review. BMC Musculoskelet Disord. 2018;19:251 pubmed publisher
    b>Treponema Pallidum (TP), the pathogen of syphilis, commonly infects bones in cases of congenital and tertiary syphilis, but it is rare in the primary and secondary stages...
  50. Zhuang L, Watt R, Mattheos N, Si M, Lai H, Lang N. Periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri-implant tissues. Clin Oral Implants Res. 2016;27:13-21 pubmed publisher
    ..g.), Treponema denticola (T.d.), Aggregatibacter actinomycetemcomitans (A.a.), Fusobacterium nucleatum (F.n...
  51. Kataoka N, Vangnai A, Pongtharangkul T, Tajima T, Yakushi T, Matsushita K, et al. Construction of CoA-dependent 1-butanol synthetic pathway functions under aerobic conditions in Escherichia coli. J Biotechnol. 2015;204:25-32 pubmed publisher
    ..eutropha, phaJ ((R)-specific enoyl-CoA hydratase) from Aeromonas caviae, ter (trans-enoyl-CoA reductase) from Treponema denticola, bld (butylraldehyde dehydrogenase) from Clostridium saccharoperbutylacetonicum, and inherent alcohol ..
  52. Zhang Y, Wang Q, Liu M, Shen H, Ma X, Zhang M, et al. [Status assessment of preconception health risk exposure among 2 030 083 males in 31 provinces during 2010-2012]. Zhonghua Yi Xue Za Zhi. 2015;95:176-80 pubmed
    ..HBsAg positive rate was 6.32% (124 274/1 965 821). And the positive screening rate of Treponema pallidum was 0.37% (7 169/1 947 021)...
  53. Yang C, Chang S, Wu B, Yang S, Liu W, Wu P, et al. Unexpectedly high prevalence of Treponema pallidum infection in the oral cavity of human immunodeficiency virus-infected patients with early syphilis who had engaged in unprotected sex practices. Clin Microbiol Infect. 2015;21:787.e1-7 pubmed publisher
    Between 2010 and 2014, we obtained swab specimens to detect Treponema pallidum, with PCR assays, from the oral cavities of 240 patients with 267 episodes of syphilis who reported engaging in unprotected sex practices...
  54. Inagaki S, Kimizuka R, Kokubu E, Saito A, Ishihara K. Treponema denticola invasion into human gingival epithelial cells. Microb Pathog. 2016;94:104-11 pubmed publisher
    ..b>Treponema denticola has been implicated in a number of potentially pathogenic processes, including periodontal tissue ..
  55. Corrêa J, Saraiva A, Queiroz Junior C, Madeira M, Duarte P, Teixeira M, et al. Arthritis-induced alveolar bone loss is associated with changes in the composition of oral microbiota. Anaerobe. 2016;39:91-6 pubmed publisher
    ..Prevotella nigrescens and Treponema denticola were detected only in the Y4 group whereas Campylobacter showae, Streptococcus mitis and Streptococcus ..
  56. Herbst de Cortina S, Bristow C, Vargas S, Perez D, Konda K, Caceres C, et al. Laboratory Evaluation of a Point-of-Care Downward-Flow Assay for Simultaneous Detection of Antibodies to Treponema pallidum and Human Immunodeficiency Virus. J Clin Microbiol. 2016;54:1922-1924 pubmed publisher
    ..This rapid assay detected HIV and Treponema pallidum serum antibodies with sensitivities of 100% (95% confidence interval [CI], 95.9% to 100%) and 87...
  57. de Mast Q, Molhoek J, van der Ven A, Gray W, de Groot P, Jusabani A, et al. Antiphospholipid Antibodies and the Risk of Stroke in Urban and Rural Tanzania: A Community-Based Case-Control Study. Stroke. 2016;47:2589-95 pubmed publisher
    ..antibodies were determined in stored plasma, as well as IgG antibodies against Treponema pallidum. Data from 158 stroke cases and 369 controls were analyzed...
  58. Sheng P, Huang J, Zhang Z, Wang D, Tian X, Ding J. Construction and Characterization of a Cellulolytic Consortium Enriched from the Hindgut of Holotrichia parallela Larvae. Int J Mol Sci. 2016;17: pubmed
    ..classes Clostridia, Epsilonproteobacteria, and Betaproteobacteria, and genera Arcobacter, Treponema, Comamonas, and Clostridium...
  59. Men S, Shang F, Han C, Song J, Han J. [Analysis of the Detection Results of the Syphilis Specific Antibody in Blood Donors by Chemiluminescence Method and Enzyme Linked Immunosorbent Assay]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017;25:226-230 pubmed publisher
    To investigate the application value of chemiluminescence method (CMIA) detection of Treponema pallidum (TP) specific antibodies in the blood test...
  60. Zeng Y, Zeng D, Ni X, Zhu H, Jian P, Zhou Y, et al. Microbial community compositions in the gastrointestinal tract of Chinese Mongolian sheep using Illumina MiSeq sequencing revealed high microbial diversity. AMB Express. 2017;7:75 pubmed publisher
    ..The present study also revealed the core genera of Prevotella, Bacteroides, Ruminococcus, Oscillospira, Treponema, and Desulfovibrio in the GIT...
  61. Usin M, Tabares S, Menso J, de Albera E, Sembaj A. Generalized aggressive periodontitis: microbiological composition and clinical parameters in non-surgical therapy. Acta Odontol Latinoam. 2016;29:255-261 pubmed
    ..sondaje encada sextante para identificar mediante técnica de biología molecular: Porphyromonas gingivalis, Treponema denticola, forsythia Tannerella, Prevotella intermedia, y Aggregatibacter actinomycetemcomitans...
  62. Pinilla G, Campos L, Durán A, Navarrete J, Muñoz L. Detección de Treponema pallidum subespecie pallidum para el diagnóstico de sífilis congénita mediante reacción en cadena de la polimerasa anidada. Biomedica. 2018;38:128-35 pubmed publisher
    Introducción. La sífilis es una enfermedad producida por Treponema pallidum subespecie pallidum cuya incidencia mundial es de 12 millones de casos por año, aproximadamente; de estos, más de dos millones se presentan en ..
  63. Sanfilippo A, Freeman K, Schmitz J. Analytical Comparison of the Architect Syphilis TP and Liaison Treponema Assay Automated Chemiluminescent Immunoassays and their Performance in a Reverse Syphilis Screening Algorithm. J Clin Microbiol. 2018;: pubmed publisher
    ..Syphilis incidence has increased in the United States since 2000 (1, 2) and remains a global public health concern (3, 4).…. ..
  64. Nayar G, Gauna A, Chukkapalli S, Velsko I, Kesavalu L, Cha S. Polymicrobial infection alter inflammatory microRNA in rat salivary glands during periodontal disease. Anaerobe. 2016;38:70-75 pubmed publisher
    ..by oral lavage consisting of polymicrobial inocula, namely Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola, or sham-infected for 12 weeks (n = 6)...
  65. Bale B, Doneen A, Vigerust D. High-risk periodontal pathogens contribute to the pathogenesis of atherosclerosis. Postgrad Med J. 2017;93:215-220 pubmed publisher
    ..i>Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola or Fusobacterium nucleatum There are three accepted essential elements in the pathogenesis ..
  66. Li Y, Ruby J, Wu H. Kanamycin Resistance Cassette for Genetic Manipulation of Treponema denticola. Appl Environ Microbiol. 2015;81:4329-38 pubmed publisher
    b>Treponema denticola has been recognized as an important oral pathogen of the "red complex" bacterial consortium that is associated with the pathogenesis of endodontal and periodontal diseases...
  67. Adler C, Malik R, Browne G, Norris J. Diet may influence the oral microbiome composition in cats. Microbiome. 2016;4:23 pubmed publisher
    ..p?<?0.01) and Treponema spp. (p?<?0.01)...
  68. Nagano K, Hasegawa Y, Yoshida Y, Yoshimura F. Comparative analysis of motility and other properties of Treponema denticola strains. Microb Pathog. 2017;102:82-88 pubmed publisher
    The periodontitis-associated pathogen Treponema denticola is a spirochetal bacterium that swims by rotating its cell body like a corkscrew using periplasmic flagella...
  69. Saw S, Zhao H, Tan P, Saw B, Sethi S. Evaluation of the automated ADVIA centaur® XP syphilis assay for serological testing. Diagn Microbiol Infect Dis. 2017;88:7-11 pubmed publisher
    ..tested on the ARCHITECT i4000SR system (Abbott Diagnostics, Lake Forest, IL, USA) and confirmed by the Treponema pallidum particle agglutination assay (TPPA) (SERODIA-TPPA, Fujirebio Diagnostics Inc., Malvern, PA, USA)...
  70. Tse J, Chan M, Ferry J, Deshpande V, Sohani A, Nardi V, et al. Syphilis of the Aerodigestive Tract. Am J Surg Pathol. 2017;: pubmed publisher
    Syphilis, a sexually transmitted infection caused by the Gram-negative bacterium Treponema pallidum, is increasing in prevalence in the United States...
  71. Torrungruang K, Jitpakdeebordin S, Charatkulangkun O, Gleebbua Y. Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Treponema denticola / Prevotella intermedia Co-Infection Are Associated with Severe Periodontitis in a Thai Population. PLoS ONE. 2015;10:e0136646 pubmed publisher
    ..of Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Treponema denticola (Td), and Prevotella intermedia (Pi) in subgingival plaque were performed using real-time polymerase ..
  72. Read P, Tagg K, Jeoffreys N, Guy R, Gilbert G, Donovan B. Treponema pallidum Strain Types and Association with Macrolide Resistance in Sydney, Australia: New TP0548 Gene Types Identified. J Clin Microbiol. 2016;54:2172-4 pubmed publisher
    Strain typing of Treponema pallidum, using the three-target enhanced classification scheme, was performed with 191 samples obtained between 2004 and 2011 in Sydney, Australia. The most common strain type was 14d/g (92/191 samples [48%])...
  73. Luthra A, Anand A, Hawley K, Ledoyt M, La Vake C, Caimano M, et al. A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326. J Bacteriol. 2015;197:1906-20 pubmed publisher
    We recently demonstrated that TP_0326 is a bona fide rare outer membrane protein (OMP) in Treponema pallidum and that it possesses characteristic BamA bipartite topology...
  74. Šmajs D, Paštěková L, Grillová L. Macrolide Resistance in the Syphilis Spirochete, Treponema pallidum ssp. pallidum: Can We Also Expect Macrolide-Resistant Yaws Strains?. Am J Trop Med Hyg. 2015;93:678-83 pubmed publisher
    b>Treponema pallidum ssp. pallidum (TPA) causes over 10 million new cases of syphilis worldwide whereas T. pallidum ssp. pertenue (TPE), the causative agent of yaws, affects about 2.5 million people...
  75. Nakajima T, Okui T, Ito H, Nakajima M, Honda T, Shimada Y, et al. Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy. Antimicrob Agents Chemother. 2016;60:1779-87 pubmed publisher
    ..The proportions of red complex bacteria, i.e., Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia, which are the representative periodontopathic bacteria, were significantly ..
  76. Jang J, Song I, Baek K, Choi Y, Ji S. Immunologic characteristics of human gingival fibroblasts in response to oral bacteria. J Periodontal Res. 2017;52:447-457 pubmed publisher
    ..Differential degradation of proteins by the six bacterial species was observed: P. gingivalis and Treponema denticola degraded proteins well, whereas the other species degraded proteins to a relatively lower degree...
  77. Bai Y, Niu F, Liu L, Sha H, Wang Y, Zhao S. Tertiary syphilis in the lumbar spine: a case report. BMC Infect Dis. 2017;17:513 pubmed publisher
    ..Serum treponema pallidum hemagglutination (TPHA) test was positive...
  78. Leite F, Nascimento G, Demarco F, Gomes B, Pucci C, Martinho F. Prevalence of treponema species detected in endodontic infections: systematic review and meta-regression analysis. J Endod. 2015;41:579-87 pubmed publisher
    ..analysis aimed to calculate a combined prevalence estimate and evaluate the prevalence of different Treponema species in primary and secondary endodontic infections, including symptomatic and asymptomatic cases...
  79. Sales Peres S, de Moura Grec P, Yamashita J, Torres E, Dionísio T, Leite C, et al. Periodontal status and pathogenic bacteria after gastric bypass: a cohort study. J Clin Periodontol. 2015;42:530-6 pubmed publisher
    ..for quantification of the periodontopathogenic bacteria Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Prevotella intermedia using q-PCR; body mass index (BMI) and for collection of the individual's ..
  80. Posautz A, Loncaric I, Lundin M, Hoffmann D, Lavazza A, Kelemen Z, et al. Health screening of free-ranging European brown hares (Lepus europaeus) on the German North-Sea island Pellworm. Acta Vet Scand. 2015;57:43 pubmed publisher
    ..Sera of hares were tested for European Brown Hare Syndrome (EBHS) by enzyme linked immunosorbent assay, and for Treponema sp. by indirect immunofluorescent test. Additional testing was performed when deemed necessary...
  81. Pozzobon T, Facchinello N, Bossi F, Capitani N, Benagiano M, Di Benedetto G, et al. Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway. Sci Rep. 2016;6:18785 pubmed publisher
    Over 10 million people every year become infected by Treponema pallidum and develop syphilis, a disease with broad symptomatology that, due to the difficulty to eradicate the pathogen from the highly vascularized secondary sites of ..
  82. Tanaka Kumazawa K, Kikuchi Y, Sano Kokubun Y, Shintani S, Yakushiji M, Kuramitsu H, et al. Characterization of a potential ABC-type bacteriocin exporter protein from Treponema denticola. BMC Oral Health. 2016;17:18 pubmed publisher
    b>Treponema denticola is strongly associated with the development of periodontal disease. Both synergistic and antagonistic effects are observed among bacterial species in the process of biofilm formation...
  83. Lyons T, Bielak A, Doyle E, Kuhla B. Variations in methane yield and microbial community profiles in the rumen of dairy cows as they pass through stages of first lactation. J Dairy Sci. 2018;101:5102-5114 pubmed publisher
    ..Prevotella dominated the rumen of cows followed by Succinclasticum; Treponema, Fibrobacter, Ruminococcus, and Bifidobacterium were also in high abundance relative to other bacterial genera...
  84. AlZahal O, Valdes E, McBride B. Analysis of the distal gut bacterial community by 454-pyrosequencing in captive giraffes (Giraffa camelopardalis). Zoo Biol. 2016;35:42-50 pubmed publisher
    ..These OTUs were Treponema, an unidentified OTU belonging to the order Bacteroidales, and Ruminococcus...
  85. Monje Fernández L, Martín García E, Cordero Coma M. Syphilitic placoid chorioretinitis. A case-report. Arch Soc Esp Oftalmol. 2016;91:232-5 pubmed publisher
    ..Clinical manifestations of ocular syphilis are extremely heterogeneous and may mimic several aetiologies. Anti-treponema treatment usually induces a quick and positive response in affected patients...
  86. Cocks N, Rainima Qaniuci M, Yalen C, MacLeod C, Nakolinivalu A, Migchelsen S, et al. Community seroprevalence survey for yaws and trachoma in the Western Division of Fiji. Trans R Soc Trop Med Hyg. 2016;110:582-587 pubmed
    ..A dried blood spot was collected which was tested using the Treponema pallidum particle agglutination (TPPA) test and an ELISA to detect antibodies against Pgp3...
  87. Amsalu A, Ferede G, Assegu D. High seroprevalence of syphilis infection among pregnant women in Yiregalem hospital southern Ethiopia. BMC Infect Dis. 2018;18:109 pubmed publisher
    ..for syphilis using rapid plasma regain (RPR) test and those found seropositive were further confirmed by Treponema pallidum haemagglutination assay (TPHA) test following the manufacturer's instruction...
  88. Song X, Tian L, Zou H, Sun H. Analysis of the clinical diagnosis data of four experimental detection methods for pediatric syphilis. Minerva Pediatr. 2015;: pubmed
    ..plasma reagin (RPR) test, the colloidal gold test (SYP), the enzyme-linked immuno-sorbent assay (ELISA) and the Treponema pallidum particle agglutination (TPPA) test. The relevant experimental data were analyzed by SPSS 13.0 software...
  89. Li Z, Feng Z, Liu P, Yan C. Screening for antibodies against Treponema pallidum with chemiluminescent microparticle immunoassay: analysis of discordant serology results and clinical characterization. Ann Clin Biochem. 2016;53:588-92 pubmed publisher
    ..Recent availability of a chemiluminescent microparticle immunoassay for detecting antibodies against Treponema pallidum has led several laboratories in China to adopt chemiluminescent microparticle immunoassay for screening ..
  90. Marchesan J, Morelli T, Moss K, Barros S, Ward M, Jenkins W, et al. Association of Synergistetes and Cyclodipeptides with Periodontitis. J Dent Res. 2015;94:1425-31 pubmed publisher
    ..OT360/OT362, Filifactor alocis, Treponema lecithinolyticum, Eubacterium saphenum, Desulfobulbus sp./OT041, and Mogibacterium timidum...
  91. Walther António M, Chen J, Multinu F, Hokenstad A, Distad T, Cheek E, et al. Potential contribution of the uterine microbiome in the development of endometrial cancer. Genome Med. 2016;8:122 pubmed
    ..Firmicutes (Anaerostipes, ph2, Dialister, Peptoniphilus, 1-68, Ruminococcus, and Anaerotruncus), Spirochaetes (Treponema), Actinobacteria (Atopobium), Bacteroidetes (Bacteroides and Porphyromonas), and Proteobacteria (Arthrospira)...
  92. Lu H, Li K, Gong W, Yan L, Gu X, Chai Z, et al. High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis. Emerg Microbes Infect. 2015;4:e10 pubmed publisher
    ..We used polymerase chain reaction technology to detect a 23S rRNA A2058G mutation in Treponema pallidum in 109 specimens from syphilis patients...