Brachyspira hyodysenteriae

Summary

Alias: Brachyspira hyodysenteriae (Harris et al. 1972) Ochiai et al. 1998, Serpulina hyodysenteriae, Serpulina hyodysenteriae (Harris et al. 1972) Stanton 1992, Treponema hyodysenteriae, Treponema hyodysenteriae Harris et al. 1972 (Approved Lists 1980), Serpula hyodysenteriae, Serpula hyodysenteriae (Harris et al. 1972) Stanton et al. 1991

Top Publications

  1. Zeeh F, Klausmann S, Masserey Y, Nathues H, Perreten V, Rohde J. Isolation of Brachyspira hyodysenteriae from a crow (Corvus corone) in close proximity to commercial pigs. Vet J. 2018;236:111-112 pubmed publisher
    The aim of this study was to determine whether crows (Corvus corone) can harbour Brachyspira hyodysenteriae, the cause of swine dysentery, and whether the organism carried by crows is related to strains infecting pigs. B...
  2. De Luca S, Nicholson P, Magistrali C, García Martín A, Rychener L, Zeeh F, et al. Transposon-associated lincosamide resistance lnu(C) gene identified in Brachyspira hyodysenteriae ST83. Vet Microbiol. 2018;214:51-55 pubmed publisher
    Treatment of Swine Dysentery (SD) caused by Brachyspira hyodysenteriae (B. hyodysenteriae) is carried out using antimicrobials such as macrolides, lincosamides and pleuromutilins leading to the selection of resistant strains...
  3. Rugna G, Bonilauri P, Carra E, Bergamini F, Luppi A, Gherpelli Y, et al. Sequence types and pleuromutilin susceptibility of Brachyspira hyodysenteriae isolates from Italian pigs with swine dysentery: 2003-2012. Vet J. 2015;203:115-9 pubmed publisher
    Swine dysentery is a mucohaemorrhagic colitis of pigs caused by infection with Brachyspira hyodysenteriae. The disease can be controlled by treatment with antimicrobial agents, with the pleuromutilins tiamulin and valnemulin being widely ..
  4. Wilberts B, Warneke H, Bower L, Kinyon J, Burrough E. Comparison of culture, polymerase chain reaction, and fluorescent in situ hybridization for detection of Brachyspira hyodysenteriae and "Brachyspira hampsonii" in pig feces. J Vet Diagn Invest. 2015;27:41-6 pubmed publisher
    Swine dysentery is characterized by mucohemorrhagic diarrhea and can occur following infection by Brachyspira hyodysenteriae or "Brachyspira hampsonii "...
  5. Wilberts B, Arruda P, Warneke H, Erlandson K, Hammer J, Burrough E. Cessation of clinical disease and spirochete shedding after tiamulin treatment in pigs experimentally infected with "Brachyspira hampsonii". Res Vet Sci. 2014;97:341-7 pubmed publisher
    ..5% is approved in the United States for treatment of dysentery caused by Brachyspira hyodysenteriae at 0.006% in the water...
  6. La T, Phillips N, Thomson J, Hampson D. Absence of a set of plasmid-encoded genes is predictive of reduced pathogenic potential in Brachyspira hyodysenteriae. Vet Res. 2014;45:131 pubmed publisher
    The gene content of 14 strains of the intestinal spirochaete Brachyspira hyodysenteriae was compared using a DNA microarray...
  7. Wilberts B, Arruda P, Kinyon J, Frana T, Wang C, Magstadt D, et al. Investigation of the impact of increased dietary insoluble fiber through the feeding of distillers dried grains with solubles (DDGS) on the incidence and severity of Brachyspira-associated colitis in pigs. PLoS ONE. 2014;9:e114741 pubmed publisher
    Diet has been implicated as a major factor impacting clinical disease expression of swine dysentery and Brachyspira hyodysenteriae colonization. However, the impact of diet on novel pathogenic strongly beta-hemolytic Brachyspira spp...
  8. Quintana Hayashi M, Mahu M, De Pauw N, Boyen F, Pasmans F, Martel A, et al. The levels of Brachyspira hyodysenteriae binding to porcine colonic mucins differ between individuals, and binding is increased to mucins from infected pigs with de novo MUC5AC synthesis. Infect Immun. 2015;83:1610-9 pubmed publisher
    b>Brachyspira hyodysenteriae colonizes the pig colon, resulting in mucohemorrhagic diarrhea and growth retardation...
  9. Song Y, La T, Phillips N, Hampson D. Development of a serological ELISA using a recombinant protein to identify pig herds infected with Brachyspira hyodysenteriae. Vet J. 2015;206:365-70 pubmed publisher
    b>Brachyspira hyodysenteriae is an anaerobic spirochaete that can induce swine dysentery (SD), a severe mucohaemorrhagic colitis in grower and fattener pigs...

More Information

Publications31

  1. Pearson H, Toribio J, Lapidge S, Hernández Jover M. Evaluating the risk of pathogen transmission from wild animals to domestic pigs in Australia. Prev Vet Med. 2016;123:39-51 pubmed publisher
    ..and Campylobacter spp. from European starlings (Sturnus vulgarus); Brachyspira hyodysenteriae, Lawsonia intracellularis and Salmonella spp...
  2. Löbert S, Zimmermann W, Bürki S, Frey J, Nathues H, Scheer P, et al. Occurrence of Brachyspira hyodysenteriae in multiplier pig herds in Switzerland. Tierarztl Prax Ausg G Grosstiere Nutztiere. 2016;44:13-8 pubmed publisher
    ..B. hyodysenteriae have been detected in a Swiss multiplier herd, which underlines the threat of potential spread by replacement pigs. Consequently, a Brachyspira monitoring programme was established for Swiss multiplier herds. ..
  3. Aller Morán L, Martínez Lobo F, Rubio P, Carvajal A. Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriae. Res Vet Sci. 2015;103:51-3 pubmed publisher
    ..This study aims to evaluate the in vitro anti-Brachyspira hyodysenteriae activity of flumequine...
  4. Mahu M, De Pauw N, Vande Maele L, Verlinden M, Boyen F, Ducatelle R, et al. Variation in hemolytic activity of Brachyspira hyodysenteriae strains from pigs. Vet Res. 2016;47:66 pubmed publisher
    b>Brachyspira hyodysenteriae is the primary cause of swine dysentery, which is responsible for major economic losses to the pig industry worldwide. The hemolytic activity of 10 B...
  5. Quintana Hayashi M, Navabi N, Mahu M, Venkatakrishnan V, Fernandez H, Haesebrouck F, et al. Neutrophil elastase and IL17 expressed in the pig colon during Brachyspira hyodysenteriae infection synergistically with the pathogen induce increased mucus transport speed and production via MAPK3. Infect Immun. 2017;: pubmed publisher
    i>Brachyspira hyodysenteriae colonizes the pig colon resulting in mucoid hemorragic diarrhea and mucus layer changes...
  6. Giacomini E, Gasparrini S, Lazzaro M, Scali F, Boniotti M, Corradi A, et al. The role of transportation in the spread of Brachyspira hyodysenteriae in fattening farms. BMC Vet Res. 2018;14:10 pubmed publisher
    Direct and indirect contact among animals and holdings are important in the spread of Brachyspira hyodysenteriae. The objective of this study was to investigate the role of slaughterhouse vehicles in spreading B...
  7. Mirajkar N, Johnson T, Gebhart C. Complete Genome Sequence of Brachyspira hyodysenteriae Type Strain B-78 (ATCC 27164). Genome Announc. 2016;4: pubmed publisher
    Reported herein is the complete genome sequence of the type strain B-78 (ATCC 27164) of Brachyspira hyodysenteriae, the etiological agent of swine dysentery. The 3.1-Mb genome consists of a 3...
  8. Herbst W, Schneider S, Baljer G, Barth S. An update of Brachyspira hyodysenteriae serotyping. Res Vet Sci. 2017;111:135-139 pubmed publisher
    ..Results indicate that B. hyodysenteriae has a high degree of serological heterogeneity that has probably differently developed in diverse geographical areas over time. This situation represents a challenge for vaccine development. ..
  9. La T, Phillips N, Hampson D. An Investigation into the Etiological Agents of Swine Dysentery in Australian Pig Herds. PLoS ONE. 2016;11:e0167424 pubmed publisher
    ..seen in grower/finisher pigs and caused by infection with the anaerobic intestinal spirochete Brachyspira hyodysenteriae. More recently, however, the newly described species Brachyspira hampsonii and Brachyspira suanatina ..
  10. Heidrich C, Mitova S, Schedlbauer A, Connell S, Fucini P, Steenbergen J, et al. The Novel Aminomethylcycline Omadacycline Has High Specificity for the Primary Tetracycline-Binding Site on the Bacterial Ribosome. Antibiotics (Basel). 2016;5: pubmed publisher
    ..three antibiotics are inhibited by mutations in the 16S rRNA that mediate resistance to tetracycline in Brachyspira hyodysenteriae, Helicobacter pylori, Mycoplasma hominis, and Propionibacterium acnes...
  11. Mirajkar N, Phillips N, La T, Hampson D, Gebhart C. Characterization and Recognition of Brachyspira hampsonii sp. nov., a Novel Intestinal Spirochete That Is Pathogenic to Pigs. J Clin Microbiol. 2016;54:2942-2949 pubmed
    ..is a mucohemorrhagic colitis of swine classically caused by infection with the intestinal spirochete Brachyspira hyodysenteriae Since around 2007, cases of SD have occurred in North America associated with a different strongly beta-..
  12. Hampson D, La T, Phillips N, Holyoake P. Brachyspira hyodysenteriae isolated from apparently healthy pig herds following an evaluation of a prototype commercial serological ELISA. Vet Microbiol. 2016;191:15-9 pubmed publisher
    ..The classical aetiological agent is the anaerobic intestinal spirochaete Brachyspira hyodysenteriae, although "Brachyspira hampsonii" and Brachyspira suanatina also cause SD...
  13. Mirajkar N, Davies P, Gebhart C. Antimicrobial Susceptibility Patterns of Brachyspira Species Isolated from Swine Herds in the United States. J Clin Microbiol. 2016;54:2109-19 pubmed publisher
    Outbreaks of swine dysentery, caused by Brachyspira hyodysenteriae and the recently discovered "Brachyspira hampsonii," have reoccurred in North American swine herds since the late 2000s...
  14. Lee H, Piao D, Lee J, Choi J, Bok J, Cho C, et al. Artificially designed recombinant protein composed of multiple epitopes of foot-and-mouth disease virus as a vaccine candidate. Microb Cell Fact. 2017;16:33 pubmed publisher
    ..To increase solubility and stability of 5BT, it was conjugated with BmpB, the membrane protein B of Brachyspira hyodysenteriae (B5BT)...
  15. Zeeh F, Nathues H, Frey J, Muellner P, Fellström C. A review of methods used for studying the molecular epidemiology of Brachyspira hyodysenteriae. Vet Microbiol. 2017;207:181-194 pubmed publisher
    ..hyodysenteriae, B. pilosicoli, B. intermedia, B. murdochii, B. innocens, B. suanatina and B. hampsonii. Brachyspira hyodysenteriae is especially relevant in pigs as it causes swine dysentery and hence considerable economic losses to ..
  16. Mahu M, Pasmans F, Vranckx K, De Pauw N, Vande Maele L, Vyt P, et al. Presence and mechanisms of acquired antimicrobial resistance in Belgian Brachyspira hyodysenteriae isolates belonging to different clonal complexes. Vet Microbiol. 2017;207:125-132 pubmed publisher
    ..However, acquired antimicrobial resistance is increasingly observed in Brachyspira hyodysenteriae. In this study, the Minimal Inhibitory Concentrations (MIC) of six antimicrobial compounds for 30 recent ..
  17. de Nova P, Carvajal A, Prieto M, Rubio P. In vitro susceptibility of Brachyspira hyodysenteriae to a commercial citrus fruit extract. Res Vet Sci. 2017;115:318-324 pubmed publisher
    b>Brachyspira hyodysenteriae is the main etiological agent of swine dysentery (SD)...
  18. Hampson D, Wang P. Colonic Spirochetes: What Has Genomics Taught Us?. Curr Top Microbiol Immunol. 2018;415:273-294 pubmed publisher
    ..knowledge occurred in 2009 when, for the first time, the whole genome sequence of a Brachyspira strain (Brachyspira hyodysenteriae strain WA1) was obtained...
  19. Burrough E, Arruda B, Plummer P. Comparison of the Luminal and Mucosa-Associated Microbiota in the Colon of Pigs with and without Swine Dysentery. Front Vet Sci. 2017;4:139 pubmed publisher
    Colonic contents and mucosal scrapings from pigs inoculated with Brachyspira hyodysenteriae or Brachyspira hampsonii were collected at necropsy and classified as either positive (n?=?29) or negative (n?=?7) for ..
  20. Mahu M, Boyen F, Canessa S, Zavala Marchan J, Haesebrouck F, Martel A, et al. An avirulent Brachyspira hyodysenteriae strain elicits intestinal IgA and slows down spread of swine dysentery. Vet Res. 2017;48:59 pubmed publisher
    Swine dysentery caused by Brachyspira hyodysenteriae, results in substantial economic losses in swine producing countries worldwide...
  21. Gasparrini S, Alborali G, Pitozzi A, Guarneri F, Giacomini E, Baldo V, et al. Characterization of Brachyspira hyodysenteriae isolates from Italy by multilocus sequence typing and multiple locus variable number tandem repeat analysis. J Appl Microbiol. 2017;123:340-351 pubmed publisher
    ..typing (MLST) and multiple locus variable number tandem repeat analysis (MLVA) techniques to characterize Brachyspira hyodysenteriae isolates and to investigate the relationship between pleuromutilin resistance and genetic variability.
  22. Brown J, Gilliland S, Ruiz Albert J, Holden D. Characterization of pit, a Streptococcus pneumoniae iron uptake ABC transporter. Infect Immun. 2002;70:4389-98 pubmed
    ..pneumoniae operon, named pit, encoding proteins with similarity to components of a putative Brachyspira hyodysenteriae iron uptake ABC transporter, Bit. An S...