domestic ferret

Summary

Alias: black ferret, ferret, Mustela putorius furo, Mustela putoris furo, Mustela furo, Mustela putorius furo Linnaeus, 1758

Top Publications

  1. Hannemann A, Christie J, Flatman P. Functional expression of the Na-K-2Cl cotransporter NKCC2 in mammalian cells fails to confirm the dominant-negative effect of the AF splice variant. J Biol Chem. 2009;284:35348-58 pubmed publisher
    ..report the cloning and functional expression of untagged and unmodified versions of the major splice variants from ferret kidney (fNKCC2A, -B, and -F) in human embryonic kidney (HEK) 293 cells...
  2. Ma Y, Zhang Y, Liang X, Lou F, Oglesbee M, Krakowka S, et al. Origin, evolution, and virulence of porcine deltacoronaviruses in the United States. MBio. 2015;6:e00064 pubmed publisher
    ..with Hong Kong and South Korean PdCV strains and coronaviruses (CoVs) of Asian leopard cats and Chinese ferret-badgers...
  3. Thakkar V, Cox R, Sawatsky B, da Fontoura Budaszewski R, Sourimant J, Wabbel K, et al. The Unstructured Paramyxovirus Nucleocapsid Protein Tail Domain Modulates Viral Pathogenesis through Regulation of Transcriptase Activity. J Virol. 2018;92: pubmed publisher
    ..To probe an effect of Ntail truncations on viral pathogenesis, recombinant CDVs were analyzed in a lethal CDV/ferret model of morbillivirus disease...
  4. Carter D, Darby C, Johnson S, Carlock M, Kirchenbaum G, Allen J, et al. Elicitation of Protective Antibodies against a Broad Panel of H1N1 Viruses in Ferrets Preimmune to Historical H1N1 Influenza Viruses. J Virol. 2017;91: pubmed publisher
    ..first report demonstrating the effectiveness of a broadly reactive or universal influenza vaccine in a preimmune ferret model...
  5. Rotti P, Xie W, Poudel A, Yi Y, Sun X, Tyler S, et al. Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets. Am J Pathol. 2018;188:876-890 pubmed publisher
    ..An animal model of cystic fibrosis-related diabetes has been developed in the ferret, which progresses through phases of glycemic abnormalities because of islet remodeling during and after exocrine ..
  6. Rosen B, Evans T, Moll S, Gray J, Liang B, Sun X, et al. Infection is Not Required for Mucoinflammatory Lung Disease in CFTR-knockout Ferrets. Am J Respir Crit Care Med. 2018;: pubmed publisher
    ..We evaluated whether continuous antibiotic therapy protects the CF lung from disease using a ferret model that rapidly acquires lethal bacterial lung infections in the absence of antibiotics...
  7. Music N, Reber A, Kim M, York I, Kang S. Supplementation of H1N1pdm09 split vaccine with heterologous tandem repeat M2e5x virus-like particles confers improved cross-protection in ferrets. Vaccine. 2016;34:466-473 pubmed publisher
    ..The Split+M2e5x ferret group showed evidence of cross-reactive protection, including faster recovery from weight loss, and reduced ..
  8. Paquette S, Banner D, Huang S, Almansa R, Leon A, Xu L, et al. Influenza Transmission in the Mother-Infant Dyad Leads to Severe Disease, Mammary Gland Infection, and Pathogenesis by Regulating Host Responses. PLoS Pathog. 2015;11:e1005173 pubmed publisher
    ..virus infection and transmission in breastfeeding mothers and infants utilizing our developed infant-mother ferret influenza model. Infants acquired severe disease and mortality following infection...
  9. Kozak R, He S, Kroeker A, de La Vega M, Audet J, Wong G, et al. Ferrets Infected with Bundibugyo Virus or Ebola Virus Recapitulate Important Aspects of Human Filovirus Disease. J Virol. 2016;90:9209-23 pubmed publisher
    ..Furthermore, several hallmarks of human filoviral disease were recapitulated in the ferret model, including substantial decreases in lymphocyte and platelet counts and dysregulation of key biochemical ..

More Information

Publications256 found, 100 shown here

  1. Belser J, Creager H, Sun X, Gustin K, Jones T, Shieh W, et al. Mammalian Pathogenesis and Transmission of H7N9 Influenza Viruses from Three Waves, 2013-2015. J Virol. 2016;90:4647-4657 pubmed publisher
    ..and transmissibility of H7N9 viruses isolated during the second and third waves, through 2015, in the mouse and ferret models...
  2. Sun X, Pulit Penaloza J, Belser J, Pappas C, Pearce M, Brock N, et al. Pathogenesis and Transmission of Genetically Diverse Swine-Origin H3N2 Variant Influenza A Viruses from Multiple Lineages Isolated in the United States, 2011-2016. J Virol. 2018;92: pubmed publisher
    ..The efficient respiratory droplet transmission exhibited by some of the H3N2v viruses in the ferret model combined with the existing evidence of low immunity against such viruses in young children and older adults ..
  3. Baz M, Paskel M, Matsuoka Y, Zengel J, Cheng X, Treanor J, et al. A Single Dose of an Avian H3N8 Influenza Virus Vaccine Is Highly Immunogenic and Efficacious against a Recently Emerged Seal Influenza Virus in Mice and Ferrets. J Virol. 2015;89:6907-17 pubmed publisher
    ..The latter observation was confirmed in a ferret study...
  4. Dipiazza A, Richards K, Batarse F, Lockard L, Zeng H, Garcia Sastre A, et al. Flow Cytometric and Cytokine ELISpot Approaches To Characterize the Cell-Mediated Immune Response in Ferrets following Influenza Virus Infection. J Virol. 2016;90:7991-8004 pubmed publisher
    ..the MHC locus in ferrets within commercial populations, a finding of considerable interest in efforts to move the ferret model forward for influenza vaccine and challenge studies...
  5. Yui T, Ohmachi T, Matsuda K, Okamoto M, Taniyama H. Histochemical and immunohistochemical characterization of chordoma in ferrets. J Vet Med Sci. 2015;77:467-73 pubmed publisher
    ..Therefore, immunohistochemistry using these antibodies can be useful for the characterization of ferret chordoma.
  6. Marjuki H, Mishin V, Chesnokov A, De La Cruz J, Davis C, Villanueva J, et al. Neuraminidase Mutations Conferring Resistance to Oseltamivir in Influenza A(H7N9) Viruses. J Virol. 2015;89:5419-26 pubmed publisher
    ..Thus, these clinical outcomes measured in the ferret model may correlate with clinically relevant oseltamivir resistance in humans...
  7. Sun X, Olivier A, Yi Y, Pope C, Hayden H, Liang B, et al. Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets. Am J Pathol. 2014;184:1309-22 pubmed publisher
    ..In summary, these studies demonstrate that the CF ferret model develops gastrointestinal pathology similar to CF patients.
  8. Diep B, Hilliard J, Le V, Tkaczyk C, Le H, Tran V, et al. Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia. Antimicrob Agents Chemother. 2017;61: pubmed publisher
    ..MEDI4893* prophylaxis reduced disease severity in ferret and rabbit pneumonia models against both community-associated methicillin-resistant S...
  9. Korenkov D, Laurie K, Reading P, Carolan L, Chan K, Isakova Sivak I, et al. Safety, immunogenicity and protection of A(H3N2) live attenuated influenza vaccines containing wild-type nucleoprotein in a ferret model. Infect Genet Evol. 2018;64:95-104 pubmed publisher
    ..All vaccinated animals were protected against infection with heterologous H3N2 influenza A viruses. Thus, LAIV with a 5:3 genome composition is safe, immunogenic and can induce cross-protective immunity. ..
  10. Nagasaka A, Shinoda T, Kawaue T, Suzuki M, Nagayama K, Matsumoto T, et al. Differences in the Mechanical Properties of the Developing Cerebral Cortical Proliferative Zone between Mice and Ferrets at both the Tissue and Single-Cell Levels. Front Cell Dev Biol. 2016;4:139 pubmed
    ..To address how mouse and ferret neuroepithelia may differ physically in a quantitative manner, we used atomic force microscopy to determine that ..
  11. Doria Torra G, Vidaña B, Ramis A, Amarilla S, Martinez J. Coronavirus Infection in Ferrets: Antigen Distribution and Inflammatory Response. Vet Pathol. 2016;53:1180-1186 pubmed
    Multisystemic granulomatous lesions are the most common finding in ferrets infected by ferret systemic coronavirus (FRSCV)...
  12. Music N, Reber A, Kim J, York I. Peripheral Leukocyte Migration in Ferrets in Response to Infection with Seasonal Influenza Virus. PLoS ONE. 2016;11:e0157903 pubmed publisher
    ..with influenza virus infection, we measured cell trafficking, via flow cytometry, to various tissues in the ferret model following infection with an A(H3N2) human seasonal influenza virus (A/Perth/16/2009)...
  13. Vidaña B, Martínez J, Martínez Orellana P, García Migura L, Montoya M, Martorell J, et al. Heterogeneous pathological outcomes after experimental pH1N1 influenza infection in ferrets correlate with viral replication and host immune responses in the lung. Vet Res. 2014;45:85 pubmed publisher
    ..patterns of influenza strains that produce different disease outcomes in humans could be reproduced in a ferret model...
  14. Kakehi M, Ikenaka Y, Nakayama S, Kawai Y, Watanabe K, Mizukawa H, et al. Uridine Diphosphate-Glucuronosyltransferase (UGT) Xenobiotic Metabolizing Activity and Genetic Evolution in Pinniped Species. Toxicol Sci. 2015;147:360-9 pubmed publisher
    ..and UGT1A7-1A10 are paralogous genes to UGT1A1 and UGTA6, respectively, and their numbers were lower in cat, ferret and Pacific walrus than in human, rat, and dog...
  15. Liu Y, Massare M, Pearce M, Sun X, Belser J, Maines T, et al. Recombinant virus-like particles elicit protective immunity against avian influenza A(H7N9) virus infection in ferrets. Vaccine. 2015;33:2152-8 pubmed publisher
    ..In this study, we evaluated the immunogenicity and protective efficacy of a H7N9 VLP vaccine in the ferret challenge model...
  16. Dubey J, Trupkiewicz J, Verma S, Mowery J, Adedoyin G, Georoff T, et al. Atypical fatal sarcocystosis associated with Sarcocystis neurona in a White-nosed coati (Nasua narica molaris). Vet Parasitol. 2017;247:80-84 pubmed publisher
    ..reports of clinical EPM-like disease have been documented in a zebra, raccoon, domestic cat, domestic dog, ferret, skunk, mink, lynx, red panda and fisher...
  17. Goineau S, Castagne V. Comparison of three preclinical models for nausea and vomiting assessment. J Pharmacol Toxicol Methods. 2016;82:45-53 pubmed publisher
    ..2mg/kg, i.v.). The assessment of emesis in the ferret or in the dog displays a strong predictive value...
  18. Chan R, Chan L, Mok C, Lai J, Tao K, Obadan A, et al. Replication of H9 influenza viruses in the human ex vivo respiratory tract, and the influence of neuraminidase on virus release. Sci Rep. 2017;7:6208 pubmed publisher
    ..Using recombinant H9 viruses previously evaluated in the ferret, we found that viruses which replicated well in the ferret did not replicate to the same extent in the human ex ..
  19. Broadbent A, Santos C, Paskel M, Matsuoka Y, Lu J, Chen Z, et al. Replication of live attenuated cold-adapted H2N2 influenza virus vaccine candidates in non human primates. Vaccine. 2015;33:193-200 pubmed publisher
    ..Taken together, our data show that in NHPs the AA ca virus more closely reflects the human experience than mice or ferret studies...
  20. Pappas C, Yang H, Carney P, Pearce M, Katz J, Stevens J, et al. Assessment of transmission, pathogenesis and adaptation of H2 subtype influenza viruses in ferrets. Virology. 2015;477:61-71 pubmed publisher
    ..a swine H2N3 (A/swine/Missouri/2124514/2006 [swMO]), and a human H2N2 (A/England/10/1967 [Eng/67]) virus using the ferret model as a mammalian host...
  21. Ng P, Böhm R, Hartley Tassell L, Steen J, Wang H, Lukowski S, et al. Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors. Nat Commun. 2014;5:5750 pubmed publisher
    ..Genomic analysis reveals an ancient, nine-exon deletion in the ferret CMAH gene that is shared by the Pinnipedia and Musteloidia members of the Carnivora...
  22. Stittelaar K, de Waal L, van Amerongen G, Veldhuis Kroeze E, Fraaij P, van Baalen C, et al. Ferrets as a Novel Animal Model for Studying Human Respiratory Syncytial Virus Infections in Immunocompetent and Immunocompromised Hosts. Viruses. 2016;8: pubmed publisher
    ..and non-human primates, we have evaluated the potential benefits of an HRSV infection model in ferrets (Mustela putorius furo)...
  23. Horn C. The medical implications of gastrointestinal vagal afferent pathways in nausea and vomiting. Curr Pharm Des. 2014;20:2703-12 pubmed
    ..of preclinical nausea and vomiting research in academia and pharmaceutical companies, including the dog, cat, ferret, and musk shrew...
  24. Naguib M, Ulrich R, Kasbohm E, Eng C, Hoffmann D, Grund C, et al. Natural Reassortants of Potentially Zoonotic Avian Influenza Viruses H5N1 and H9N2 from Egypt Display Distinct Pathogenic Phenotypes in Experimentally Infected Chickens and Ferrets. J Virol. 2017;91: pubmed publisher
    ..Enhanced zoonotic properties were not predicted for any of these clones, and this prediction was confirmed by ferret inoculation experiments: neither the H5N1 parent virus nor two selected clones induced severe clinical symptoms or ..
  25. Wang B, Li W, Zhou J, Li B, Zhang W, Yang W, et al. Chevrier's Field Mouse (Apodemus chevrieri) and Père David's Vole (Eothenomys melanogaster) in China Carry Orthohepeviruses that form Two Putative Novel Genotypes Within the Species Orthohepevirus C. Virol Sin. 2018;33:44-58 pubmed publisher
    ..were highly divergent from the two assigned genotypes: HEV-C1 derived from rat and shrew, and HEV-C2 derived from ferret and possibly mink...
  26. Clark A, DeDiego M, Anderson C, Wang J, Yang H, Nogales A, et al. Antigenicity of the 2015-2016 seasonal H1N1 human influenza virus HA and NA proteins. PLoS ONE. 2017;12:e0188267 pubmed publisher
    ..measurable antigenic differences between the NA protein of circulating strains and the vaccine strain using both ferret and human antisera...
  27. Jackson Thompson B, Kim S, Jaiswal S, Scott J, Jones S, Morris C, et al. Brugia malayi infection in ferrets - A small mammal model of lymphatic filariasis. PLoS Negl Trop Dis. 2018;12:e0006334 pubmed publisher
    ..Finally, we developed a novel ferret PET/CT lymphoscintigraphy method demonstrating substantial changes in lymphatic anatomy and function as early as 3 ..
  28. Suzuki T, Hasebe A. A provisional complete genome-based genotyping system for rotavirus species C from terrestrial mammals. J Gen Virol. 2017;98:2647-2662 pubmed publisher
    ..RVCs identified in Japan from 2002 to 2010, along with those from multiple human, bovine, porcine, canine and ferret RVCs reported in several previous studies...
  29. Lin Y, Chu P, Chang M, Hsiao K, Lin J, Liu H. Spatial Temporal Dynamics and Molecular Evolution of Re-Emerging Rabies Virus in Taiwan. Int J Mol Sci. 2016;17:392 pubmed publisher
    ..Surprisingly, rabies virus (RABV) was identified in a dead Formosan ferret badger in July 2013. Later, more infected ferret badgers were reported from different geographic regions of Taiwan...
  30. Sawatsky B, Cattaneo R, von Messling V. Canine Distemper Virus Spread and Transmission to Naïve Ferrets: Selective Pressure on SLAM-Dependent Entry. J Virol. 2018;: pubmed publisher
    ..A recombinant CDV expressing the mutated attachment protein regained the ability to infect ferret lymphocytes in vitro, but its replication was not as efficient as wild-type CDV...
  31. Alves Beuttemmüller E, Woodward A, Rash A, Dos Santos Ferraz L, Fernandes Alfieri A, Alfieri A, et al. Characterisation of the epidemic strain of H3N8 equine influenza virus responsible for outbreaks in South America in 2012. Virol J. 2016;13:45 pubmed publisher
    ..Antigenic analyses were completed by haemagglutination-inhibition assay using post-infection ferret sera...
  32. Di Girolamo N, Selleri P. Medical and Surgical Emergencies in Ferrets. Vet Clin North Am Exot Anim Pract. 2016;19:431-64 pubmed publisher
    In the last few years, significant improvement in diagnosis and treatment of ferret emergencies has occurred. Scientific advances demonstrated the need of specific practices when dealing with emergencies in ferrets...
  33. Gary J, Langohr I, Lim A, Bolin S, Bolin C, Moore I, et al. Enteric colonization by staphylococcus delphini in four ferret kits with diarrhoea. J Comp Pathol. 2014;151:314-7 pubmed publisher
    Four, 1-to 4-week-old ferret kits were submitted to the Diagnostic Center for Population and Animal Health at Michigan State University for post-mortem examination...
  34. Camp J, Bagci U, Chu Y, Squier B, Fraig M, Uriarte S, et al. Lower Respiratory Tract Infection of the Ferret by 2009 H1N1 Pandemic Influenza A Virus Triggers Biphasic, Systemic, and Local Recruitment of Neutrophils. J Virol. 2015;89:8733-48 pubmed publisher
    ..Sites in the H1N1pdm virus-infected ferret lung with high FDG uptake had high levels of proliferative epithelium...
  35. Zhou X, Kataoka M, Liu Z, Takeda N, Wakita T, Li T. Characterization of self-assembled virus-like particles of dromedary camel hepatitis e virus generated by recombinant baculoviruses. Virus Res. 2015;210:8-17 pubmed publisher
    ..An antigenic analysis demonstrated that DcHEV was cross-reactive with G1, G3-G6, ferret and rat HEVs, and DcHEV showed a stronger cross-reactivity to G1 G3-G6 HEV than it did to rat and ferret HEV...
  36. Uchida S, Horie R, Sato H, Kai C, Yoneda M. Possible role of the Nipah virus V protein in the regulation of the interferon beta induction by interacting with UBX domain-containing protein1. Sci Rep. 2018;8:7682 pubmed publisher
    ..Satterfield B.A. et al. have also revealed that V protein is required for the pathogenicity of henipavirus in a ferret infection model. However, the complete functions of NiV V have not been clarified...
  37. Apanaskevich M, Apanaskevich D. Reinstatement of Dermacentor bellulus (Acari: Ixodidae) as a Valid Species Previously Confused with D. taiwanensis and Comparison of All Parasitic Stages. J Med Entomol. 2015;52:573-95 pubmed publisher
    ..been collected from wild boars, bears, panda, dog, and human; the immature stages are known from rodents, hares, ferret-badger, and bamboo-partridge. D...
  38. Blumer R, Maurer Gesek B, Gesslbauer B, Blumer M, Pechriggl E, Davis López de Carrizosa M, et al. Palisade Endings Are a Constant Feature in the Extraocular Muscles of Frontal-Eyed, But Not Lateral-Eyed, Animals. Invest Ophthalmol Vis Sci. 2016;57:320-31 pubmed publisher
    ..Thirteen species, some frontal-eyed (human, monkey, cat, and ferret), and others lateral-eyed (pig, sheep, calf, horse, rabbit, rat, mouse, gerbil, and guinea pig) were analyzed...
  39. Martínez Martinez M, de Juan Romero C, Fernandez V, Cárdenas A, Gotz M, Borrell V. A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels. Nat Commun. 2016;7:11812 pubmed publisher
    ..roles in the development of the neocortex, with particular relevance in gyrencephalic species such as human and ferret, where it contains abundant basal radial glia cells (bRGCs) that promote cortical expansion...
  40. Mathiesen R, Chriel M, Struve T, Heegaard P. Quantitative immunoassay for mink immunoglobulin in serum and milk. Acta Vet Scand. 2018;60:36 pubmed publisher
    ..immunoassay for quantification of mink IgG in serum and milk, using a commercially available polyclonal goat anti-ferret IgG antibody cross-reactive with mink IgG as both the catching and the detection antibody, in a sandwich format ..
  41. Snyder J, Wood T, Corry K, Moralejo D, Parikh P, Juul S. Ontogeny of white matter, toll-like receptor expression, and motor skills in the neonatal ferret. Int J Dev Neurosci. 2018;: pubmed publisher
    ..to characterize white matter development and determine TLR3 and TLR4 expression and accumulation in the neonatal ferret brain...
  42. Davis Z, Sun C, Derieg B, Chapman B, Cheng H. Epibatidine blocks eye-specific segregation in ferret dorsal lateral geniculate nucleus during stage III retinal waves. PLoS ONE. 2015;10:e0118783 pubmed publisher
    ..In contrast to the development of the mouse, ferret eye-specific segregation is not complete at the start of stage III glutamatergic retinal waves, and the remaining ..
  43. Tsai K, Hsu W, Chuang W, Chang J, Tu Y, Tsai H, et al. Emergence of a sylvatic enzootic formosan ferret badger-associated rabies in Taiwan and the geographical separation of two phylogenetic groups of rabies viruses. Vet Microbiol. 2016;182:28-34 pubmed publisher
    ..rabies-free in humans and domestic animals for five decades until July 2013, when surprisingly, three Formosan ferret badgers (FB) were diagnosed with rabies...
  44. Meliopoulos V, Karlsson E, Kercher L, Cline T, Freiden P, Duan S, et al. Human H7N9 and H5N1 influenza viruses differ in induction of cytokines and tissue tropism. J Virol. 2014;88:12982-91 pubmed publisher
    ..and nasopharynx-associated lymphoid tissue than H5N1 viruses, which may explain the enhanced transmission in ferret models...
  45. Lu Z, Percie du Sert N, Chan S, Yeung C, Lin G, Yew D, et al. Differential hypoglycaemic, anorectic, autonomic and emetic effects of the glucagon-like peptide receptor agonist, exendin-4, in the conscious telemetered ferret. J Transl Med. 2014;12:327 pubmed publisher
    ..Therefore, we investigated if the ferret, a carnivore with demonstrated translation capability in emesis research, would identify the emetic potential of ..
  46. Youngblood M, Chen W, Mishra A, Enamandram S, Sanganahalli B, Motelow J, et al. Rhythmic 3-4Hz discharge is insufficient to produce cortical BOLD fMRI decreases in generalized seizures. Neuroimage. 2015;109:368-77 pubmed publisher
    ..To examine the possible contributions of these differences, we developed a ferret model that exhibits 3-4 Hz spike-wave seizures in the presence of a sulcated cortex...
  47. Snapper L, Oranç C, Hawley Dolan A, Nissel J, Winner E. Your kid could not have done that: even untutored observers can discern intentionality and structure in abstract expressionist art. Cognition. 2015;137:154-165 pubmed publisher
    ..People see more than they think they do in abstract art. These findings tell us something about the nature of non-figurative art. They also tell us something about the human tendency to ferret out intentionality.
  48. Rouder J. The what, why, and how of born-open data. Behav Res Methods. 2016;48:1062-9 pubmed publisher
    Although many researchers agree that scientific data should be open to scrutiny to ferret out poor analyses and outright fraud, most raw data sets are not available on demand...
  49. Autieri C, Miller C, Scott K, Kilgore A, Papscoe V, Garner M, et al. Systemic Coronaviral Disease in 5 Ferrets. Comp Med. 2015;65:508-16 pubmed
    The prevalence of reported systemic coronaviral disease in ferrets (Mustela putorius furo), which resembles the dry form of feline infectious peritonitis, has been increasing in the literature since its initial diagnosis and ..
  50. Redmon J, Shrestha B, Cerundolo R, Court M. Soy isoflavone metabolism in cats compared with other species: urinary metabolite concentrations and glucuronidation by liver microsomes. Xenobiotica. 2016;46:406-15 pubmed publisher
    ..b>Ferret and mongoose livers were also ranked in the lowest four species. 5...
  51. Chan K, Carolan L, Korenkov D, Druce J, McCaw J, Reading P, et al. Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection. J Infect Dis. 2018;218:406-417 pubmed publisher
    ..We investigated viral interference between hRSV and 2009 pandemic influenza A(H1N1) virus (A[H1N1]pdm09) in the ferret model. Infection with A(H1N1)pdm09 prevented subsequent infection with hRSV...
  52. Nakamura K, Shirakura M, Suzuki Y, Naito T, Fujisaki S, Tashiro M, et al. Development of a high-yield reassortant influenza vaccine virus derived from the A/Anhui/1/2013 (H7N9) strain. Vaccine. 2016;34:328-33 pubmed publisher
    ..1 and -10.2 grew well with hemagglutination titer 1024. These viruses reacted well with a ferret antiserum raised against the original A/Anhui/1/2013 virus. Ferret antiserum against NIIDRG-10...
  53. Nishii K, Reese G, Moran E, Sparks J. Multiscale computational model of fluid flow and matrix deformation in decellularized liver. J Mech Behav Biomed Mater. 2016;57:201-14 pubmed publisher
    ..tissue to measure parenchymal fluid pressure ex-situ in portal vein-perfused native (n=5) and decellularized (n=7) ferret liver, for flow rates from 3-12mL/min...
  54. Wills S, Beaufrère H, Brisson B, Fraser R, Smith D. Pancreatitis and Systemic Coronavirus Infection in a Ferret (Mustela putorius furo). Comp Med. 2018;68:208-211 pubmed
    A 1-y-old spayed female ferret (Mustela putorius furo) was referred for additional diagnostic evaluation after physical examination by the referring veterinarian revealed a cranial abdominal mass...
  55. Keating P, Nodal F, Gananandan K, Schulz A, King A. Behavioral sensitivity to broadband binaural localization cues in the ferret. J Assoc Res Otolaryngol. 2013;14:561-72 pubmed publisher
    Although the ferret has become an important model species for studying both fundamental and clinical aspects of spatial hearing, previous behavioral work has focused on studies of sound localization and spatial release from masking in the ..
  56. Heath M, Swan N, Marriott A, Silman N, Hallis B, Prevosto C, et al. Comparison of a novel microcrystalline tyrosine adjuvant with aluminium hydroxide for enhancing vaccination against seasonal influenza. BMC Infect Dis. 2017;17:232 pubmed publisher
    ..the MCT adjuvant formulation was compared to alum adjuvanted TIV and to TIV administered without adjuvant using a ferret challenge model to determine vaccine efficacy. The MCT was found to possess high protein-binding capacity...
  57. Koster F, Gouveia K, Zhou Y, Lowery K, Russell R, Macinnes H, et al. Exhaled aerosol transmission of pandemic and seasonal H1N1 influenza viruses in the ferret. PLoS ONE. 2012;7:e33118 pubmed publisher
  58. Griffiths T, Hall D. Mapping pitch representation in neural ensembles with fMRI. J Neurosci. 2012;32:13343-7 pubmed
    ..encourage caution when comparing BOLD activity in humans and macaques to recordings from single neurons in ferret and marmoset in the previous mini-review...
  59. Brajon D, Valois A, Waton J, Schmutz J, Barbaud A. [Immunoallergic skin manifestations associated with new pets: three cases]. Ann Dermatol Venereol. 2014;141:588-92 pubmed publisher
    ..We first of all report the case of a female patient with eczema lesions on areas skin coming into contact with a ferret, with removal of the animal resulting in wound healing, followed by two patients presenting atypical polymorphous ..
  60. Sellers K, Bennett D, Fröhlich F. Frequency-band signatures of visual responses to naturalistic input in ferret primary visual cortex during free viewing. Brain Res. 2015;1598:31-45 pubmed publisher
    ..Therefore, the two mesoscale activity states delineated in this study may define the degree of engagement of the circuit with the processing of sensory input. ..
  61. Pulit Penaloza J, Jones J, Sun X, Jang Y, Thor S, Belser J, et al. Antigenically Diverse Swine Origin H1N1 Variant Influenza Viruses Exhibit Differential Ferret Pathogenesis and Transmission Phenotypes. J Virol. 2018;92: pubmed publisher
    ..the genetic and phenotypic characteristics of the virus, genome sequence analysis, antigenic characterization, and ferret pathogenesis and transmissibility experiments were performed...
  62. Smith D, Simmonds P, Jameel S, Emerson S, Harrison T, Meng X, et al. Consensus proposals for classification of the family Hepeviridae. J Gen Virol. 2014;95:2223-32 pubmed publisher
    ..B (isolates from chicken), Orthohepevirus C (isolates from rat, greater bandicoot, Asian musk shrew, ferret and mink) and Orthohepevirus D (isolates from bat)...
  63. Enkirch T, von Messling V. Ferret models of viral pathogenesis. Virology. 2015;479-480:259-70 pubmed publisher
    ..To provide decision criteria for the use of this animal model, its strengths and limitations will be discussed. ..
  64. Santymire R, Lavin S, Branvold Faber H, Kreeger J, Marinari P. Effect of dietary vitamin E and prey supplementation on semen quality in male black-footed ferrets (Mustela nigripes). Theriogenology. 2015;84:217-25 pubmed publisher
    Over the recent years, the captive population of the endangered black-footed ferret (Mustela nigripes; ferret) has experienced a decline in normal sperm (NS) morphology (from 50% to 16%), which may be linked to inbreeding depression or it ..
  65. Nguyen D, Jang Y, Nguyen T, Jones J, Shepard S, Yang H, et al. Shifting Clade Distribution, Reassortment, and Emergence of New Subtypes of Highly Pathogenic Avian Influenza A(H5) Viruses Collected from Vietnamese Poultry from 2012 to 2015. J Virol. 2017;91: pubmed publisher
    ..A/Sichuan/26221/2014 (H5N6) virus was developed, and ferret antisera generated against this virus were demonstrated to inhibit some but not all clade 2.3.4...
  66. Reber A, Music N, Kim J, Gansebom S, Chen J, York I. Extensive T cell cross-reactivity between diverse seasonal influenza strains in the ferret model. Sci Rep. 2018;8:6112 pubmed publisher
    ..T cell epitopes demonstrated extensive cross-reactivity between diverse influenza strains in outbred animals, with NP implicated as a significant antigenic target demonstrating extensive cross-reactivity for both CD4+ and CD8+ T cells. ..
  67. Shih T, Chiang J, Wu H, Inoue S, Tsai C, Kuo S, et al. Human Exposure to Ferret Badger Rabies in Taiwan. Int J Environ Res Public Health. 2018;15: pubmed publisher
    On 17 July 2013, Taiwan confirmed multiple cases of the rabies virus (RABV) in the wild Taiwan Ferret badger (TFB) (Melogale moschata) member of the family Mustelidae...
  68. Johansson F, Jirenhed D, Rasmussen A, Zucca R, Hesslow G. Memory trace and timing mechanism localized to cerebellar Purkinje cells. Proc Natl Acad Sci U S A. 2014;111:14930-4 pubmed publisher
    ..We show here that a cerebellar Purkinje cell in a ferret can learn to respond to a specific input with a temporal pattern of activity consisting of temporally specific ..
  69. Cmielewski P, Farrow N, Donnelley M, McIntyre C, Penny Dimri J, Kuchel T, et al. Transduction of ferret airway epithelia using a pre-treatment and lentiviral gene vector. BMC Pulm Med. 2014;14:183 pubmed publisher
    ..Using the normal ferret, this study sought to determine whether ferret airway epithelia could be transduced with a lysophosphatidylcholine ..
  70. Stitt I, Galindo Leon E, Pieper F, Hollensteiner K, Engler G, Engel A. Auditory and visual interactions between the superior and inferior colliculi in the ferret. Eur J Neurosci. 2015;41:1311-20 pubmed publisher
    ..Reciprocal coupling between the IC and SC therefore probably serves the dynamic integration of visual and auditory representations of space. ..
  71. Campbell R, Schulz A, King A, Schnupp J. Brief sounds evoke prolonged responses in anesthetized ferret auditory cortex. J Neurophysiol. 2010;103:2783-93 pubmed publisher
    ..In this paper, we show that under ketamine/medetomidine anesthesia, neurons in ferret auditory cortex usually exhibit complex sustained responses...
  72. Kim D, Anderson B. Repeated threat (without harm) in a living environment potentiates defensive behavior. Behav Brain Res. 2015;279:31-40 pubmed publisher
    ..three days, half the rats (threat stress condition) received unpredictable threats (simultaneous puff of air with ferret dander, abrupt flash of light, and an abrupt sound) when crossing the central position of the tunnel (random order ..
  73. Li T, Yang T, Yoshizaki S, Ami Y, Suzaki Y, Ishii K, et al. Ferret hepatitis E virus infection induces acute hepatitis and persistent infection in ferrets. Vet Microbiol. 2016;183:30-6 pubmed publisher
    b>Ferret hepatitis E virus (HEV), a novel hepatitis E virus, has been identified in ferrets. However, the pathogenicity of ferret HEV remains unclear...
  74. Watson M, Cazzini P, Mayer J, Gottdenker N, Reavill D, Parry N, et al. Histology and immunohistochemistry of severe inflammatory bowel disease versus lymphoma in the ferret (Mustela putorius furo). J Vet Diagn Invest. 2016;28:198-206 pubmed publisher
    Inflammatory bowel disease (IBD) is a common disorder of ferrets (Mustela putorius furo) that may progress to lymphoma. Although routine histology is used to distinguish between these diseases, misclassifications may occur...
  75. Horner A, Hanna J, Biknevicius A. Crouching to fit in: the energetic cost of locomotion in tunnels. J Exp Biol. 2016;219:3420-3427 pubmed
    ..study, the energetics and kinematics of simulated tunnel locomotion by two unrelated semi-fossorial mammals, the ferret and degu, were analyzed using open-flow respirometry and digital video...
  76. Bajo V, Leach N, Cordery P, Nodal F, King A. The cholinergic basal forebrain in the ferret and its inputs to the auditory cortex. Eur J Neurosci. 2014;40:2922-40 pubmed publisher
    ..the distribution of cholinergic neurons in the basal forebrain and their inputs to the auditory cortex of the ferret, a species used increasingly in studies of auditory learning and plasticity...
  77. Luk G, Leung C, Sia S, Choy K, Zhou J, Ho C, et al. Transmission of H7N9 Influenza Viruses with a Polymorphism at PB2 Residue 627 in Chickens and Ferrets. J Virol. 2015;89:9939-51 pubmed publisher
    ..For SCk1772, positive selection for K627 over E627 was observed in ferrets during the chicken-to-ferret or ferret-to-ferret transmission...
  78. Joo N, Krouse M, Choi J, Cho H, Wine J. Inhibition of airway surface fluid absorption by cholinergic stimulation. Sci Rep. 2016;6:20735 pubmed publisher
    ..this phenomenon, we studied inward short-circuit currents (Isc) in tracheal mucosa from human, sheep, pig, ferret, and rabbit and in two types of cultured cells. Basal Isc was inhibited 20-70% by the ENaC inhibitor, benzamil...
  79. Fabrizius A, Hoff M, Engler G, Folkow L, Burmester T. When the brain goes diving: transcriptome analysis reveals a reduced aerobic energy metabolism and increased stress proteins in the seal brain. BMC Genomics. 2016;17:583 pubmed publisher
    ..transcriptome of the visual cortex of the hooded seal was compared with that of the ferret (Mustela putorius furo), which served as a terrestrial relative...
  80. Layton D, Xiao X, Bentley J, Lu L, Stewart C, Bean A, et al. Development of an anti-ferret CD4 monoclonal antibody for the characterisation of ferret T lymphocytes. J Immunol Methods. 2017;444:29-35 pubmed publisher
    The ferret is an established animal model for a number of human respiratory viral infections, such as influenza virus and more recently, Ebola virus...
  81. Fiorotto R, Amenduni M, Mariotti V, Cadamuro M, Fabris L, Spirli C, et al. Animal models for cystic fibrosis liver disease (CFLD). Biochim Biophys Acta Mol Basis Dis. 2018;: pubmed publisher
    ..The recent creation of novel CF animal models (i.e. pig and ferret) that better reproduce the human disease, will allow for comparative studies with species that spontaneously ..
  82. Li T, Yoshizaki S, Yang T, Kataoka M, Nakamura T, Ami Y, et al. Production of infectious ferret hepatitis E virus in a human hepatocarcinoma cell line PLC/PRF/5. Virus Res. 2016;213:283-288 pubmed publisher
    A strain of ferret hepatitis E virus (HEV), sF4370, isolated from an imported ferret was used to inoculate a human hepatocarcinoma cell line, PLC/PRF/5. The virus genome and capsid protein were detected in the cell culture supernatant...
  83. Aizawa K, Liu C, Veeramachaneni S, Hu K, Smith D, Wang X. Development of ferret as a human lung cancer model by injecting 4-(Nmethyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Lung Cancer. 2013;82:390-6 pubmed
    ..Previously we have shown the induction of lung tumor in ferrets (Mustela putorius furo) exposed to both tobacco smoke and a tobacco carcinogen (4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-..
  84. Wang X, Lei Y, Tao X, Li H, Shen X, Yu P, et al. [Sequencing and analysis of N gene of street rabies virus isolated from different hosts in Zhejiang province]. Zhonghua Liu Xing Bing Xue Za Zhi. 2014;35:837-41 pubmed
    ..through sequencing and analysis of N gene among street rabies virus isolated from different hosts (homo sapiens, ferret badger, dog) in Zhejiang province...
  85. Wiersma L, Vogelzang van Trierum S, van Amerongen G, van Run P, Nieuwkoop N, Ladwig M, et al. Pathogenesis of infection with 2009 pandemic H1N1 influenza virus in isogenic guinea pigs after intranasal or intratracheal inoculation. Am J Pathol. 2015;185:643-50 pubmed publisher
    To elucidate the pathogenesis and transmission of influenza virus, the ferret model is typically used. To investigate protective immune responses, the use of inbred mouse strains has proven invaluable...
  86. Kirchenbaum G, Ross T. Generation of Monoclonal Antibodies against Immunoglobulin Proteins of the Domestic Ferret (Mustela putorius furo). J Immunol Res. 2017;2017:5874572 pubmed publisher
    The domestic ferret (Mustela putorius furo) serves as an animal model for the study of several viruses that cause human disease, most notably influenza...
  87. Kammeyer P, Ziege S, Wellhöner S, Cichowski S, Baumgärtner W. Testicular leiomyosarcoma and marked alopecia in a cryptorchid ferret (Mustela putorius furo). Tierarztl Prax Ausg K Kleintiere Heimtiere. 2014;42:406-10 pubmed publisher
    A 3.5-year-old male ferret, bought as male castrated, was presented to the veterinarian with marked alopecia of back, neck, abdomen and tail, a pronounced sexual behaviour and weight loss. An inguinal mass of about 2...
  88. Matsumoto I, Uchida K, Chambers J, Nibe K, Sato Y, Hamasu T, et al. Hodgkin's-like lymphoma in a ferret (Mustela putorius furo). J Vet Med Sci. 2017;79:1660-1663 pubmed publisher
    A 7-year-old castrated male ferret developed unilateral cervical lymphadenomegaly over a 1-month period. Histological examination revealed proliferation of tumor cells in a diffuse and partially nodular pattern...
  89. Fehér E, Pazár P, Kovács E, Farkas S, Lengyel G, Jakab F, et al. Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome. Arch Virol. 2014;159:3401-6 pubmed publisher
    ..g., humans. ..
  90. Koel B, Mögling R, Chutinimitkul S, Fraaij P, Burke D, van der Vliet S, et al. Identification of amino acid substitutions supporting antigenic change of influenza A(H1N1)pdm09 viruses. J Virol. 2015;89:3763-75 pubmed publisher
    ..that consists of amino acid positions 151 to 159 located adjacent to the receptor binding site caused escape from ferret and human antibodies elicited after primary A(H1N1)pdm09 virus infection...
  91. Nowakowski T, Pollen A, Di Lullo E, Sandoval Espinosa C, Bershteyn M, Kriegstein A. Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells. Cell Stem Cell. 2016;18:591-6 pubmed publisher
    ..We also show that AXL expression in radial glia is conserved in developing mouse and ferret cortex and in human stem cell-derived cerebral organoids, highlighting multiple experimental systems that could be ..
  92. Chakraborty P, Prithiviraj B, Selvaraj S, Kumar B. Polychlorinated biphenyls in settled dust from informal electronic waste recycling workshops and nearby highways in urban centers and suburban industrial roadsides of Chennai city, India: Levels, congener profiles and exposure assessment. Sci Total Environ. 2016;573:1413-1421 pubmed publisher
    ..FESEM revealed that average particle size (in Ferret diameter) increased in the following order: e-waste recycling workshops (0.5μm)<nearby highways (1...