Edwardsiella tarda

Summary

Alias: "Paracolobactrum anguillimortiferum" Hoshina 1962, Edwardsiella anguillimortifera, Edwardsiella anguillimortifera (Hoshina 1962) Sakazaki and Tamura 1975, Edwardsiella tarda Ewing and McWhorter 1965, Paracolobactrum anguillimortiferum

Top Publications

  1. Umasuthan N, Bathige S, Revathy K, Nam B, Choi C, Lee J. Molecular genomic- and transcriptional-aspects of a teleost TRAF6 homolog: Possible involvement in immune responses of Oplegnathus fasciatus against pathogens. Fish Shellfish Immunol. 2015;42:66-78 pubmed publisher
    ..Putative role of OfTRAF6 in response to flagellin, LPS, poly I:C, pathogenic bacteria (Edwardsiella tarda and Streptococcus iniae) and rock bream iridovirus (RBIV) was profiled in different tissues and OfTRAF6 ..
  2. Li S, Peng W, Hao G, Li J, Geng X, Sun J. Identification and functional analysis of dual-specificity MAP kinase phosphatase 6 gene (dusp6) in response to immune challenges in Japanese flounder Paralichthys olivaceus. Fish Shellfish Immunol. 2017;60:411-419 pubmed publisher
    ..flounder immune-related tissues including head kidney, gill and spleen upon bacterial challenge with Edwardsiella tarda. Overexpression of PoDusp6 in Japanese flounder FG-9307 cells led to a significant down-regulation of ..
  3. Li S, Hao G, Peng W, Geng X, Sun J. Expression and functional characterization of vitronectin gene from Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2017;65:9-16 pubmed publisher
    ..The expression of PoVtn was also modulated by bacterial challenge with Edwardsiella tarda in Japanese flounder immune-related tissues including head kidney, gill and spleen...
  4. Hoque F, Jawahar Abraham T, Nagesh T, Kamilya D. Pseudomonas aeruginosa FARP72 Offers Protection Against Aeromonas hydrophila Infection in Labeo rohita. Probiotics Antimicrob Proteins. 2018;: pubmed publisher
    ..It showed inhibitory activity against Aeromonas caviae, A. hydrophila, Edwardsiella tarda, Pseudomonas putida, and Streptococcus agalactiae as revealed by cross and parallel streaking methods...
  5. Choi K, Shim S, An C, Nam B, Jeong J, Kim J, et al. Functional characterisation and expression analysis of recombinant serum amyloid P isoform 1 (RbSAP1) from rock bream (Oplegnathus fasciatus). Fish Shellfish Immunol. 2015;45:277-85 pubmed publisher
    ..RbSAP1 expression was dramatically up-regulated in the kidney and liver after infection with Edwardsiella tarda, Streptococcus iniae, or red seabream iridovirus...
  6. Kang C, Gu T, So J. Possible Probiotic Lactic Acid Bacteria Isolated from Oysters (Crassostrea gigas). Probiotics Antimicrob Proteins. 2017;: pubmed publisher
    ..for antimicrobial activity toward various pathogens: Vibrio parahaemolyticus, Streptococcus iniae, and Edwardsiella tarda. Eight isolates had an antibacterial activity toward V...
  7. Umasuthan N, Mothishri M, Thulasitha W, Nam B, Lee J. Molecular, genomic, and expressional delineation of a piscidin from rock bream (Oplegnathus fasciatus) with evidence for the potent antimicrobial activities of Of-Pis1 peptide. Fish Shellfish Immunol. 2016;48:154-68 pubmed publisher
    ..trials with lipopolysaccharide (LPS); polyinosinic:polycytidylic acid (poly I:C); and pathogens, including Edwardsiella tarda, Streptococcus iniae, and rock bream iridovirus (RBIV), was weak...
  8. Wang G, Wang M, Liu Y, Zhang Q, Li C, Liu P, et al. Identification, expression analysis, and antibacterial activity of NK-lysin from common carp Cyprinus carpio. Fish Shellfish Immunol. 2018;73:11-21 pubmed publisher
    ..against Staphylococcus aureus (Gram-positive), and Escherichia coli M15, Aeromonas hydrophila, as well as Edwardsiella tarda (Gram-negative), the latter two are important pathogens of aquaculture...
  9. Bathige S, Umasuthan N, Priyathilaka T, Thulasitha W, Jayasinghe J, Wan Q, et al. Molecular cloning, transcriptional profiling, and subcellular localization of signal transducer and activator of transcription 2 (STAT2) ortholog from rock bream, Oplegnathus fasciatus. Gene. 2017;626:95-105 pubmed publisher
    ..was detected after immune challenge experiments with viral (rock bream irido virus; RBIV), bacterial (Edwardsiella tarda and Streptococcus iniae), and immune stimulants (poly I:C and LPS)...

More Information

Publications162 found, 100 shown here

  1. Bathige S, Umasuthan N, Godahewa G, Thulasitha W, Jayasinghe J, Wan Q, et al. Molecular insights of two STAT1 variants from rock bream (Oplegnathus fasciatus) and their transcriptional regulation in response to pathogenic stress, interleukin-10, and tissue injury. Fish Shellfish Immunol. 2017;69:128-141 pubmed publisher
    ..Significantly modulated transcripts were noted upon viral (rock bream iridovirus [RBIV]), bacterial (Edwardsiella tarda and Streptococcus iniae), and pathogen-associated molecular pattern (lipopolysaccharide and poly I:C) ..
  2. Oh M, Bathige S, Kim Y, Lee S, Yang H, Kim M, et al. A CXCL ortholog from Hippocampus abdominalis: Molecular features and functional delineation as a pro-inflammatory chemokine. Fish Shellfish Immunol. 2017;67:218-227 pubmed publisher
    ..in blood and kidney tissues after immune stimulation by live bacteria, such as Streptococcus iniae and Edwardsiella tarda, and mitogens, such as lipopolysaccharides (LPS) and polyinosinic:polycytidylic acid (poly I:C), suggesting ..
  3. Liu J, Cao D, Liu Y, Li Z, Si Y, Wang Z, et al. Expression and functional analysis of receptor-interacting serine/threonine kinase 2 (RIP2) in Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;75:327-335 pubmed publisher
    ..In vivo, we examined the expression pattern in different tissues after being challenged with Edwardsiella tarda. PoRIP2 was up-regulated in tissues at different time points...
  4. Yang G, Xiu Y, Chen Y, Bai L, Sha Z. Identification and expression of complement component C8?, C8? and C8? gene in half-smooth tongue sole (Cynoglossus semilaevis) and C8? recombinant protein antibacterial activity analysis. Fish Shellfish Immunol. 2018;72:658-669 pubmed publisher
    ..anguillarum, Edwardsiella tarda and Vibrio parahaemolyticus...
  5. Choi K, Jeong J, Bae J, Cho D, Jung S, Hwang J, et al. Coagulation factor II from rock bream (Oplegnathus fasciatus): First report on the molecular biological function and expression analysis in the teleost. Fish Shellfish Immunol. 2016;48:145-53 pubmed publisher
    ..RbCFII expression was dramatically up-regulated in the kidney, spleen and liver after infection with Edwardsiella tarda, Streptococcus iniae, or red seabream iridovirus...
  6. He S, Wang G, Yue B, Zhou S, Zhang M. TO17: A teleost antimicrobial peptide that induces degradation of bacterial nucleic acids and inhibits bacterial infection in red drum, Sciaenops ocellatus. Fish Shellfish Immunol. 2018;72:639-645 pubmed publisher
    ..with 17 amino acids), a TFPI-1 C-terminal peptide from red drum (Sciaenops ocellatus), was active against Edwardsiella tarda. In the present study, we investigated further the antimicrobial spectrum, action mode, as well as the ..
  7. Saranya Revathy K, Umasuthan N, Whang I, Jung H, Lim B, Nam B, et al. A potential antioxidant enzyme belonging to the atypical 2-Cys peroxiredoxin subfamily characterized from rock bream, Oplegnathus fasciatus. Comp Biochem Physiol B Biochem Mol Biol. 2015;187:1-13 pubmed publisher
    ..of RbPrx5 transcription was evidenced from varying mRNA levels in head kidney post in vivo LPS-, poly I:C-, Edwardsiella tarda bacterial- and rock bream iridoviral-challenges...
  8. Thulasitha W, Whang I, Umasuthan N, Kang H, Mothishri M, Lee S, et al. A galectin related protein from Oplegnathus fasciatus: Genomic, molecular, transcriptional features and biological responses against microbial pathogens. Dev Comp Immunol. 2016;56:13-24 pubmed publisher
    ..bacteria, including Streptococcus iniae, Listeria monocytogenes, Vibrio tapetis, Escherichia coli, and Edwardsiella tarda, and a ciliate parasite, Miamiensis avidus...
  9. Li S, Peng W, Li J, Hao G, Geng X, Sun J. Characterization of Japanese flounder (Paralichthys olivaceus) Caspase1 involved in extracellular ATP-mediated immune signaling in fish. Fish Shellfish Immunol. 2017;67:536-545 pubmed publisher
    ..Japanese flounder immune-related tissues including head kidney, gill and spleen by bacterial challenge with Edwardsiella tarda. JfCaspase1 protein is comprised of 384 amino acid residues with a calculated molecular mass of 43...
  10. Li S, Chen X, Peng W, Hao G, Geng X, Zhan W, et al. Cloning and characterization of apoptosis-associated speck-like protein containing a CARD domain (ASC) gene from Japanese flounder Paralichthys olivaceus. Fish Shellfish Immunol. 2016;54:294-301 pubmed publisher
    ..In addition, the induction of PoASC was also observed in Edwardsiella tarda challenged head kidney and gill tissues...
  11. Umasuthan N, Bathige S, Noh J, Lee J. Gene structure, molecular characterization and transcriptional expression of two p38 isoforms (MAPK11 and MAPK14) from rock bream (Oplegnathus fasciatus). Fish Shellfish Immunol. 2015;47:331-43 pubmed publisher
    ..pathogen-associated molecular patterns (PAMPs: flagellin, lipopolysaccharide and poly I:C) and pathogens (Edwardsiella tarda, Streptococcus iniae and rock bream iridovirus) was investigated...
  12. Zhou A, Xie S, Wang Z, Junaid M, Fan L, Wang C, et al. Molecular cloning, characterization and expression analysis of heat shock protein 90 in albino northern snakehead Channa argus. Gene. 2017;626:173-181 pubmed publisher
    ..5, 26 and 37°C) and infected with Edwardsiella tarda (strain NO. DL1476) at different time intervals (0, 6, 12, 24, 36, 48, 72h)...
  13. Kulatunga D, Dananjaya S, Nikapitiya C, Godahewa G, Cho J, Kim C, et al. Stress-immune responses and DNA protection function of thioredoxin domain containing 12 in zebrafish (Danio rerio). Fish Shellfish Immunol. 2018;: pubmed publisher
    ..In larvae, up-regulated Zftxndc12 mRNA expression upon exposure to H2O2,Edwardsiella tarda and Saprolegnia parasitica suggests that it may involve in both stress and immune responses...
  14. Ran C, Carrias A, Williams M, Capps N, Dan B, Newton J, et al. Identification of Bacillus strains for biological control of catfish pathogens. PLoS ONE. 2012;7:e45793 pubmed publisher
    ..of the top 21 strains expressed antagonistic activity against multiple aquatic bacterial pathogens including Edwardsiella tarda, Streptococcus iniae, Yersinia ruckeri, Flavobacterium columnare, and/or the oomycete Saprolegnia ferax...
  15. Godahewa G, Bathige S, Herath H, Noh J, Lee J. Characterization of rock bream (Oplegnathus fasciatus) complement components C1r and C1s in terms of molecular aspects, genomic modulation, and immune responsive transcriptional profiles following bacterial and viral pathogen exposure. Fish Shellfish Immunol. 2015;46:656-68 pubmed publisher
    ..The putative roles of OfC1r and OfC1s in response to pathogenic bacteria (Edwardsiella tarda and Streptococcus iniae) and virus (rock bream iridovirus, RBIV) were investigated in liver and head kidney ..
  16. Jeong J, Kim J, Kim D, Park C. First molecular cloning and gene expression analysis of teleost CD42 (glycoprotein Ib beta chain) GPIb-IX-V subunit from rock bream, Oplegnathus fasciatus. Dev Comp Immunol. 2015;49:298-302 pubmed publisher
    ..Rock bream CD42 (RbCD42c) gene expression profiles were determined after infection with Streptococcus iniae, Edwardsiella tarda and red seabream iridovirus (RSIV)...
  17. Velázquez J, Acosta J, Herrera N, Morales A, Gonzalez O, Herrera F, et al. Novel IFN? homologue identified in Nile tilapia (Oreochromis niloticus) links with immune response in gills under different stimuli. Fish Shellfish Immunol. 2017;71:275-285 pubmed publisher
    ..IFN? expression was also induced in gills 24 h after Edwardsiella tarda infection suggesting its important role in immunity against intracellular bacteria...
  18. Umasuthan N, Bathige S, Whang I, Lim B, Choi C, Lee J. Insights into molecular profiles and genomic evolution of an IRAK4 homolog from rock bream (Oplegnathus fasciatus): immunogen- and pathogen-induced transcriptional expression. Fish Shellfish Immunol. 2015;43:436-48 pubmed publisher
    ..in liver and head kidney of animals challenged with potent immunogens (LPS and poly I:C) and pathogens (Edwardsiella tarda and Streptococcus iniae and rock bream iridovirus (RBIV))...
  19. Park Y, Moniruzzaman M, Lee S, Hong J, Won S, Lee J, et al. Comparison of the effects of dietary single and multi-probiotics on growth, non-specific immune responses and disease resistance in starry flounder, Platichthys stellatus. Fish Shellfish Immunol. 2016;59:351-357 pubmed publisher
    ..During the Edwardsiella tarda challenge test, the first mortality occurred on day 2...
  20. Li S, Chen X, Hao G, Geng X, Zhan W, Sun J. Identification and characterization of ATP-gated P2X2 receptor gene dominantly expressed in the Japanese flounder (Paralichthys olivaceus) head kidney macrophages. Fish Shellfish Immunol. 2016;54:312-21 pubmed publisher
    ..was significantly induced by LPS, poly(I:C) and zymosan stimulations in the HKM and PBL cells, and by Edwardsiella tarda infections in spleen and gill tissues as well...
  21. Oh M, Umasuthan N, Elvitigala D, Wan Q, Jo E, Ko J, et al. First comparative characterization of three distinct ferritin subunits from a teleost: Evidence for immune-responsive mRNA expression and iron depriving activity of seahorse (Hippocampus abdominalis) ferritins. Fish Shellfish Immunol. 2016;49:450-60 pubmed publisher
    ..modulated against pathogenic stress mounted by lipopolysaccharides (LPS), poly I:C, Streptococcus iniae, and Edwardsiella tarda. Collectively, our findings suggest that the three HaFer subunits may be involved in iron (II) homeostasis ..
  22. Jo E, Elvitigala D, Wan Q, Oh M, Oh C, Lee J. Identification and molecular profiling of DC-SIGN-like from big belly seahorse (Hippocampus abdominalis) inferring its potential relevancy in host immunity. Dev Comp Immunol. 2017;77:270-279 pubmed publisher
    ..gill and liver tissues in response to the stimulation of healthy fish with lipopolysaccharides (LPS), Edwardsiella tarda, or Streptococcus iniae...
  23. Tharuka M, Bathige S, Lee J. Molecular cloning, biochemical characterization, and expression analysis of two glutathione S-transferase paralogs from the big-belly seahorse (Hippocampus abdominalis). Comp Biochem Physiol B Biochem Mol Biol. 2017;214:1-11 pubmed publisher
    ..mRNA expression of HaGST? and HaGST? was significantly elevated upon lipopolysaccharide, Poly (I:C), and Edwardsiella tarda challenges in liver and in blood cells as well as with Streptococcus iniae challenge in blood cells...
  24. Godahewa G, Kim Y, Dananjaya S, Jayasooriya R, Noh J, Lee J, et al. Mitochondrial peroxiredoxin 3 (Prx3) from rock bream (Oplegnathus fasciatus): immune responses and role of recombinant Prx3 in protecting cells from hydrogen peroxide induced oxidative stress. Fish Shellfish Immunol. 2015;43:131-41 pubmed publisher
    ..Upon immune challenge of Edwardsiella tarda, Streptococcus iniae, rock bream iridovirus (RBIV) and lipopolysaccharide (LPS), RbPrx3 mRNA level was up-..
  25. Lee W, Ahn G, Oh J, Kim S, Kang N, Kim E, et al. A prebiotic effect of Ecklonia cava on the growth and mortality of olive flounder infected with pathogenic bacteria. Fish Shellfish Immunol. 2016;51:313-320 pubmed publisher
    ..1% or 0.5% EE also decreased the accumulative mortality of olive flounder infected by pathogenic bacteria (Edwardsiella tarda, Streptococcus iniae, and Vibrio harveyi). Overall, these results suggest that E...
  26. Chu T, Ni C, Zhang L, Wang Q, Xiao J, Zhang Y, et al. A quorum sensing-based in vivo expression system and its application in multivalent bacterial vaccine. Microb Cell Fact. 2015;14:37 pubmed publisher
    ..In this work, we constructed an in vivo antigen-expressing vector suitable for Edwardsiella tarda, an enteric Gram-negative invasive intracellular pathogen of both animals and humans...
  27. Liu F, Tang X, Sheng X, Xing J, Zhan W. Edwardsiella tarda Outer Membrane Protein C: An Immunogenic Protein Induces Highly Protective Effects in Flounder (Paralichthys olivaceus) against Edwardsiellosis. Int J Mol Sci. 2016;17: pubmed publisher
    Outer membrane protein C of Edwardsiella tarda is a major cell surface antigen and it was identified to be an immunogenic protein by Western blot using flounder (Paralichthys olivaceus) anti-recombinant OmpC (rOmpC), and anti-E...
  28. Cheng Z, Chu X, Wang S, Peng X, Li H. Six genes of ompA family shuffling for development of polyvalent vaccines against Vibrio alginolyticus and Edwardsiella tarda. Fish Shellfish Immunol. 2018;75:308-315 pubmed publisher
    ..These results indicate the expansion of polyvalent vaccine reservoir with the same shuffling genes but different primers, and promote the understanding of the mechanisms of polyvalent vaccines based on vaccine-induced innate immunity. ..
  29. Kondo H, Kawana Y, Suzuki Y, Hirono I. Comprehensive gene expression profiling in Japanese flounder kidney after injection with two different formalin-killed pathogenic bacteria. Fish Shellfish Immunol. 2014;41:437-40 pubmed publisher
    ..olivaceus, Japanese flounder were intraperitoneally injected with formalin-killed bacterial cells (FKC) of Edwardsiella tarda and Streptococcus iniae...
  30. Shao S, Lai Q, Liu Q, Wu H, Xiao J, Shao Z, et al. Phylogenomics characterization of a highly virulent Edwardsiella strain ET080813(T) encoding two distinct T3SS and three T6SS gene clusters: Propose a novel species as Edwardsiella anguillarum sp. nov. Syst Appl Microbiol. 2015;38:36-47 pubmed publisher
    ..Currently the genus Edwardsiella consists of three species Edwardsiella tarda, E. ictaluri, and E. hoshinae. Previous phylogenomic analysis revealed that E...
  31. Li S, Jia Z, Chen X, Geng X, Sun J. Identification and characterization of the cDNAs encoding the two subunits of Chinese mitten crab (Eriocheir sinensis) calcineurin: their implications in stress and immune response. Fish Shellfish Immunol. 2015;43:91-102 pubmed publisher
    ..were significantly up-regulated in haemocytes, gill, hepatopancreas, intestine and muscle in response to Edwardsiella tarda challenge in vivo. Finally, we revealed the importance of EsCN in LPS-induced nitric oxide production in E...
  32. Peng B, Su Y, Li H, Han Y, Guo C, Tian Y, et al. Exogenous alanine and/or glucose plus kanamycin kills antibiotic-resistant bacteria. Cell Metab. 2015;21:249-61 pubmed publisher
    ..Here we show that glucose and alanine abundances are greatly suppressed in kanamycin-resistant Edwardsiella tarda by GC-MS-based metabolomics. Exogenous alanine or glucose restores susceptibility of multidrug-resistant E...
  33. Buján N, Hernández Haro C, Monteoliva L, Gil C, Magariños B. Comparative proteomic study of Edwardsiella tarda strains with different degrees of virulence. J Proteomics. 2015;127:310-20 pubmed publisher
    b>Edwardsiella tarda is an enteric opportunistic pathogen that causes a great loss in aquaculture...
  34. Priyathilaka T, Elvitigala D, Whang I, Lim B, Jeong H, Yeo S, et al. Molecular characterization and transcriptional analysis of non-mammalian type Toll like receptor (TLR21) from rock bream (Oplegnathus fasciatus). Gene. 2014;553:105-16 pubmed publisher
    ..Additionally, upon stimulation with Streptococcus iniae, rock bream iridovirus (RBIV), and Edwardsiella tarda, RbTLR21 mRNA was significantly up-regulated in spleen tissues...
  35. Tsutsui S, Dotsuta Y, Ono A, Suzuki M, Tateno H, Hirabayashi J, et al. A C-type lectin isolated from the skin of Japanese bullhead shark (Heterodontus japonicus) binds a remarkably broad range of sugars and induces blood coagulation. J Biochem. 2015;157:345-56 pubmed publisher
    ..HjCL agglutinated the bacterial pathogen Edwardsiella tarda and promoted immediate clotting of shark blood, indicating that HjCL is involved in host defence on the skin ..
  36. Peng B, Ma Y, Zhang J, Li H. Metabolome strategy against Edwardsiella tarda infection through glucose-enhanced metabolic modulation in tilapias. Fish Shellfish Immunol. 2015;45:869-76 pubmed publisher
    b>Edwardsiella tarda causes fish disease and great economic loss. However, metabolic strategy against the pathogen remains unexplored...
  37. Velázquez J, Acosta J, Lugo J, Reyes E, Herrera F, Gonzalez O, et al. Discovery of immunoglobulin T in Nile tilapia (Oreochromis niloticus): A potential molecular marker to understand mucosal immunity in this species. Dev Comp Immunol. 2018;88:124-136 pubmed publisher
    ..analyzed by quantitative PCR in larval development and in different tissues of healthy or lipopolysaccharide/Edwardsiella tarda-challenged tilapia adults. The presence of IgT and IgM were detected in early stages of larval development...
  38. Zou G, Nozaki R, Kondo H, Hirono I. Cloning and expression analysis of three novel CC chemokine genes from Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2014;40:507-13 pubmed publisher
    ..In response to infection by Gram-negative Edwardsiella tarda and Gram-positive Streptococcus iniae in kidney, only Paol-SCYA106 gene expression significantly increased...
  39. Gao Y, Wu H, Wang Q, Qu J, Liu Q, Xiao J, et al. A live attenuated combination vaccine evokes effective immune-mediated protection against Edwardsiella tarda and Vibrio anguillarum. Vaccine. 2014;32:5937-44 pubmed publisher
    b>Edwardsiella tarda and Vibrio anguillarum are the two main pathogenic bacteria that cause edwardsiellosis and vibriosis in various species of fish raised in aquaculture. In our previous study, the live attenuated vaccines E...
  40. Zou P, Chang M, Li Y, Huan Zhang S, Fu J, Chen S, et al. Higher antiviral response of RIG-I through enhancing RIG-I/MAVS-mediated signaling by its long insertion variant in zebrafish. Fish Shellfish Immunol. 2015;43:13-24 pubmed publisher
    ..ssRNA virus, the Spring Viremia of Carp Virus (SVCV), and an intracellular Gram-negative bacterial pathogen Edwardsiella tarda, indicating the RLR may have a role in the recognition of both viruses and bacteria...
  41. Mohapatra S, Chakraborty T, Shimizu S, Urasaki S, Matsubara T, Nagahama Y, et al. Starvation beneficially influences the liver physiology and nutrient metabolism in Edwardsiella tarda infected red sea bream (Pagrus major). Comp Biochem Physiol A Mol Integr Physiol. 2015;189:1-10 pubmed publisher
    ..To understand the starvation-mediated physiological responses in Edwardsiella tarda infected red sea bream, especially in the liver, we performed a 20-day starvation experiment using 4 ..
  42. Li S, Chen X, Li X, Geng X, Lin R, Li M, et al. Molecular characterization of purinergic receptor P2X4 involved in Japanese flounder (Paralichthys olivaceus) innate immune response and its interaction with ATP release channel Pannexin1. Fish Shellfish Immunol. 2015;47:100-9 pubmed publisher
    ..In addition, poP2X4R was up-regulated in spleen, head kidney and gill tissues by Edwardsiella tarda infections...
  43. Castro N, Toranzo A, Magariños B. A multiplex PCR for the simultaneous detection of Tenacibaculum maritimum and Edwardsiella tarda in aquaculture. Int Microbiol. 2014;17:111-7 pubmed publisher
    ..detection of two important flatfish pathogens in marine aquaculture, Tenacibaculum maritimum and Edwardsiella tarda. In fish tissues, the average detection limit for these mPCR-amplified organisms was 2 × 10 ⁵ ± ..
  44. Lee S, Choe Y, Chon T, Kang H. Analysis of zebrafish (Danio rerio) behavior in response to bacterial infection using a self-organizing map. BMC Vet Res. 2015;11:269 pubmed publisher
    ..In this study, we observed movement behavior of zebrafish (Danio rerio) before and after infection with Edwardsiella tarda CK41 for 3 days until death...
  45. Gao Y, Tang X, Sheng X, Xing J, Zhan W. Antigen uptake and expression of antigen presentation-related immune genes in flounder (Paralichthys olivaceus) after vaccination with an inactivated Edwardsiella tarda immersion vaccine, following hyperosmotic treatment. Fish Shellfish Immunol. 2016;55:274-80 pubmed publisher
    ..e. 30‰) containing formalin-inactivated Edwardsiella tarda for 30 min...
  46. Zeng C, Tang X, Du Y, Sheng X, Xing J, Zhan W. Dynamic distribution of formalin-inactivated Edwardsiella tarda in olive flounder (Paralichthys olivaceus) post intramuscular injection. Vet Immunol Immunopathol. 2018;199:53-60 pubmed publisher
    ..olivaceus) were injected intramuscularly with 200??l of three concentrations of formalin-inactivated Edwardsiella tarda bacterin (107, 108, 109 CFU?ml-1) to investigate the ..
  47. Xue D, Guang Hua W, Yan Li S, Min Z, Yong Hua H. Black rockfish C-type lectin, SsCTL4: A pattern recognition receptor that promotes bactericidal activity and virus escape from host immune defense. Fish Shellfish Immunol. 2018;79:340-350 pubmed publisher
    ..Recombinant SsCTL4 (rSsCTL4) exhibited apparent binding activities against bacteria (Edwardsiella tarda and Vibrio anguillarum) and virus (infectious spleen and kidney necrosis virus, ISKNV)...
  48. Kim J, Lee J, Bae J, An C, Nam B, Jeong J, et al. First molecular characterisation and expression analysis of a teleost thioredoxin-interacting protein (TXNIP) gene from rock bream (Oplegnathus fasciatus). Dev Comp Immunol. 2015;52:69-74 pubmed publisher
    ..Generally, all tissues examined from fish infected with Streptococcus iniae, Edwardsiella tarda and red sea bream iridovirus (RSIV) showed significant downregulation in RbTXNIP expression compared to ..
  49. Gao Z, Nie P, Lu J, Liu L, Xiao T, Liu W, et al. Type III Secretion System Translocon Component EseB Forms Filaments on and Mediates Autoaggregation of and Biofilm Formation by Edwardsiella tarda. Appl Environ Microbiol. 2015;81:6078-87 pubmed publisher
    The type III secretion system (T3SS) of Edwardsiella tarda plays an important role in infection by translocating effector proteins into host cells...
  50. Thulasitha W, Umasuthan N, Whang I, Nam B, Lee J. Antimicrobial response of galectin-1 from rock bream Oplegnathus fasciatus: Molecular, transcriptional, and biological characterization. Fish Shellfish Immunol. 2016;50:66-78 pubmed publisher
    ..Immune challenges with live bacteria (Edwardsiella tarda and Streptococcus iniae), rock bream irido virus, and mitogens (lipopolysaccharide and poly I:C) modulated ..
  51. Kole S, Kumari R, Anand D, Kumar S, Sharma R, Tripathi G, et al. Nanoconjugation of bicistronic DNA vaccine against Edwardsiella tarda using chitosan nanoparticles: Evaluation of its protective efficacy and immune modulatory effects in Labeo rohita vaccinated by different delivery routes. Vaccine. 2018;36:2155-2165 pubmed publisher
    ..tarda in L. rohita exhibiting minimum stress to the host with maximum efficacy. ..
  52. Li M, Sun L, Li J. Edwardsiella tarda evades serum killing by preventing complement activation via the alternative pathway. Fish Shellfish Immunol. 2015;43:325-9 pubmed publisher
    b>Edwardsiella tarda is a Gram-negative bacterium with a broad host range that includes a wide variety of farmed fish as well as humans. E. tarda has long been known to be able to survive in host serum, but the relevant mechanism is unclear...
  53. Liu L, Nie P, Yu H, Xie H. Regulation of Type III Secretion of Translocon and Effector Proteins by the EsaB/EsaL/EsaM Complex in Edwardsiella tarda. Infect Immun. 2017;85: pubmed publisher
    ..system (T3SS) plays a crucial role in the pathogenesis of many Gram-negative bacteria, including Edwardsiella tarda, an important fish pathogen. Within the E...
  54. Perera N, Godahewa G, Hwang J, Kwon M, Hwang S, Lee J. Molecular, structural, and functional comparison of N lobe and C lobe of the transferrin from rock bream, Oplegnathus fasciatus, with respect to its immune response. Fish Shellfish Immunol. 2017;68:299-309 pubmed publisher
    ..Temporal assessment revealed that RbTf increased after stimulation of LPS, Edwardsiella tarda, and Streptococcus iniae post injection (p.i.)...
  55. Xu X, Liu J, Wang Y, Si Y, Wang X, Wang Z, et al. Kunitz-type serine protease inhibitor is a novel participator in anti-bacterial and anti-inflammatory responses in Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;80:22-30 pubmed publisher
    ..Its elevated expression in response to the application of Edwardsiella tarda (in vivo) and pathogen-associated molecular pattern (in vitro) suggested the involvement of Pokspi in the ..
  56. Huang W, Wang Z, Liang Y, Nie P, Huang B. Characterization of MyD88 in Japanese eel, Anguilla japonica. Fish Shellfish Immunol. 2018;81:374-382 pubmed publisher
    ..The expression level of AjMyD88 was investigated by real-time PCR in response to poly I:C stimulation and Edwardsiella tarda infection...
  57. Guan J, Xiao X, Xu S, Gao F, Wang J, Wang T, et al. Roles of RpoS in Yersinia pseudotuberculosis stress survival, motility, biofilm formation and type VI secretion system expression. J Microbiol. 2015;53:633-42 pubmed publisher
    ..While RpoS is an important regulator of flagellum biosynthesis, it is associated with biofilm development in Edwardsiella tarda. Biofilms are dense communities formed by bacteria and are important for microbe survival under unfavorable ..
  58. Li R, Yang X, Li Q, Ye S, Li H. Enhanced immune response and resistance to edwardsiellosis following dietary chitooligosaccharide supplementation in the olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2015;47:74-8 pubmed publisher
    ..05 or P < 0.01). After a 10 d Edwardsiella tarda challenge, the immune protection rates in the 0.5% and 1% COS groups were 30% and 60%, respectively...
  59. Cha Y, Lee C, Kwon J, Kang Y. Protective effects of CpG-ODN 2007 administration against Edwardsiella tarda infection in olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2017;68:327-331 pubmed publisher
    ..investigated the immunostimulatory and protective effects of CpG motif oligonucleotides (CpG-ODNs) against Edwardsiella tarda infection in olive flounder (Paralichthys olivaceus)...
  60. Tang X, Liu F, Sheng X, Xing J, Zhan W. Recombinant NADP-dependent isocitrate dehydrogenase of Edwardsiella tarda induces both Th1 and Th2 type immune responses and evokes protective efficacy against edwardsiellosis. Vaccine. 2018;36:2337-2345 pubmed publisher
    b>Edwardsiella tarda has become one of the most severe fish pathogens throughout the world...
  61. Hwang S, Bae J, Jo D, Kim K, Cho M, Jee B, et al. Gene expression and functional characterization of serum amyloid P component 2 in rock bream, Oplegnathus fasciatus. Fish Shellfish Immunol. 2015;47:521-7 pubmed publisher
    ..RbSAP2 in the liver and spleen, although this effect was not observed in the spleen following infection with Edwardsiella tarda. A high concentration of recombinant RbSAP2 (rRbSAP2) showed lower growth Streptococcus iniae than control ..
  62. Chigwechokha P, Tabata M, Shinyoshi S, Oishi K, Araki K, Komatsu M, et al. Recombinant sialidase NanA (rNanA) cleaves α2-3 linked sialic acid of host cell surface N-linked glycoprotein to promote Edwardsiella tarda infection. Fish Shellfish Immunol. 2015;47:34-45 pubmed publisher
    b>Edwardsiella tarda is one of the major pathogenic bacteria affecting both marine and freshwater fish species. Sialidase NanA expressed endogenously in E. tarda is glycosidase removing sialic acids from glycoconjugates...
  63. Fogelson S, Petty B, Reichley S, Ware C, Bowser P, Crim M, et al. Histologic and molecular characterization of Edwardsiella piscicida infection in largemouth bass (Micropterus salmoides). J Vet Diagn Invest. 2016;28:338-44 pubmed publisher
    ..analysis against existing spectral databases of recovered isolates identified these bacteria as Edwardsiella tarda Subsequent molecular analysis using repetitive sequence mediated and species-specific PCR, as well as 16S ..
  64. Guo M, Tang X, Sheng X, Xing J, Zhan W. The effects of IL-1?, IL-8, G-CSF and TNF-? as molecular adjuvant on the immune response to an E. tarda subunit vaccine in flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;77:374-384 pubmed publisher
    ..pcIL-1?, pcTNF-?, pcIL-8 and pcG-CSF) were successfully constructed, and their adjuvant potential on an Edwardsiella tarda (E. tarda) subunit vaccine OmpV (rOmpV) were comparatively analyzed in vaccinated flounder model...
  65. Li S, Peng W, Chen X, Geng X, Zhan W, Sun J. Expression and role of gap junction protein connexin43 in immune challenge-induced extracellular ATP release in Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2016;55:348-57 pubmed publisher
    ..expression in the brain, and are significantly up-regulated by LPS, poly(I:C) and zymosan challenges and Edwardsiella tarda infections as well, suggesting that PoCx43 expression was modulated by the inflammatory stresses...
  66. Oh M, Elvitigala D, Bathige S, Lee S, Kim M, Lee J. Molecular and functional characterization of caspase-8 from the big-belly seahorse (Hippocampus abdominalis). Fish Shellfish Immunol. 2016;58:650-662 pubmed publisher
    ..be significantly modulated by lipopolysaccharide, polyinosinic:polycytidylic acid, Streptococcus iniae, and Edwardsiella tarda injection...
  67. Zhou Z, Sun B, Sun L. Edwardsiella tarda Sip1: A serum-induced zinc metalloprotease that is essential to serum resistance and host infection. Vet Microbiol. 2015;177:332-40 pubmed publisher
    b>Edwardsiella tarda is a severe bacterial pathogen to a wide arrange of farmed fish. One salient virulent feature of E. tarda is a remarkable ability to survive in host serum. In this study, in order to identify E...
  68. Lyu Z, Zhao B, Koiwai K, Hirono I, Kondo H. Identification of endonuclease domain-containing 1 gene in Japanese flounder Paralichthys olivaceus. Fish Shellfish Immunol. 2016;50:43-9 pubmed publisher
    ..in vivo, total proteins from Japanese flounder kidney and spleen were extracted at 12, 24 and 72 h post Edwardsiella tarda FKC injection. The DNase activity of extracted protein was higher in treated fish than in untreated fish...
  69. Tang L, Yue S, Li G, Li J, Wang X, Li S, et al. Expression, secretion and bactericidal activity of type VI secretion system in Vibrio anguillarum. Arch Microbiol. 2016;198:751-60 pubmed publisher
    ..a correlation of the constitutive expression of T6SS with bactericidal activity against Escherichia coli and Edwardsiella tarda. The work presented here suggests that the constitutive expression of T6SS provides V...
  70. Khosravi S, Rahimnejad S, Herault M, Fournier V, Lee C, Dio Bui H, et al. Effects of protein hydrolysates supplementation in low fish meal diets on growth performance, innate immunity and disease resistance of red sea bream Pagrus major. Fish Shellfish Immunol. 2015;45:858-68 pubmed publisher
    ..1 g) were fed one of the test diets to apparent satiation twice daily for 13 weeks and then challenged by Edwardsiella tarda. At the end of the feeding trial, significantly (P < 0...
  71. Katharios P, Kokkari C, Dourala N, Smyrli M. First report of Edwardsiellosis in cage-cultured sharpsnout sea bream, Diplodus puntazzo from the Mediterranean. BMC Vet Res. 2015;11:155 pubmed publisher
    b>Edwardsiella tarda, is a serious bacterial pathogen affecting a broad range of aquaculture fish species...
  72. Kim M, Choi S, Yang J, Kim K. Production of RNase III-knockout, auxotrophic Edwardsiella tarda mutant for delivery of long double-stranded RNA and evaluation of its immunostimulatory potential. Fish Shellfish Immunol. 2017;68:474-478 pubmed publisher
    ..tarda mutant (Δalr ΔrncΔasd E. tarda) showed significantly higher expressions of TLR22, Mx1, and ISG15 genes, indicating a potential to increase type I interferon responses. ..
  73. Li S, Hao G, Xu Y, Wang N, Li J, Geng X, et al. Functional characterization of purinergic P2Y2 and P2Y12 receptors involved in Japanese flounder (Paralichthys olivaceus) innate immune responses. Fish Shellfish Immunol. 2018;75:208-215 pubmed publisher
    ..expression of P2Y2 and P2Y12 receptors was markedly modulated by PAMPs stimulation and Edwardsiella tarda infection...
  74. Xie H, Lu J, Zhou Y, Yi J, Yu X, Leung K, et al. Identification and functional characterization of the novel Edwardsiella tarda effector EseJ. Infect Immun. 2015;83:1650-60 pubmed publisher
    b>Edwardsiella tarda is a Gram-negative enteric pathogen that causes hemorrhagic septicemia in fish and gastro- and extraintestinal infections in humans. The type III secretion system (T3SS) of E...
  75. Beck B, Lee S, Kim D, Park J, Lee H, Kwon S, et al. A Lactococcus lactis BFE920 feed vaccine expressing a fusion protein composed of the OmpA and FlgD antigens from Edwardsiella tarda was significantly better at protecting olive flounder (Paralichthys olivaceus) from edwardsiellosis than single antige. Fish Shellfish Immunol. 2017;68:19-28 pubmed publisher
    ..lactis BFE920 expressing Edwardsiella tarda outer membrane protein A (OmpA), flagellar hook protein D (FlgD), or a fusion antigen of the two...
  76. Lu J, Wang W, Wang G, Zhang H, Zhou Y, Gao Z, et al. Edwardsiella tarda EscE (Orf13 Protein) Is a Type III Secretion System-Secreted Protein That Is Required for the Injection of Effectors, Secretion of Translocators, and Pathogenesis in Fish. Infect Immun. 2016;84:2-10 pubmed publisher
    The type III secretion system (T3SS) of Edwardsiella tarda is crucial for its intracellular survival and pathogenesis in fish. The orf13 gene (escE) of E. tarda is located 84 nucleotides (nt) upstream of esrC in the T3SS gene cluster...
  77. Li S, Chen X, Hao G, Geng X, Zhan W, Sun J. Identification and characterization of a novel NOD-like receptor family CARD domain containing 3 gene in response to extracellular ATP stimulation and its role in regulating LPS-induced innate immune response in Japanese flounder (Paralichthys olivac. Fish Shellfish Immunol. 2016;50:79-90 pubmed publisher
    ..In addition, we showed that poNLRC3 mRNA expression was up-regulated in response to LPS and Edwardsiella tarda immune challenges...
  78. Li H, Chu X, Peng B, Peng X. DNA shuffling approach for recombinant polyvalent OmpAs against V. alginolyticus and E. tarda infections. Fish Shellfish Immunol. 2016;58:508-513 pubmed publisher
    ..alginolyticus, Edwardsiella tarda and Escherichia coli...
  79. Kim J, Jeong J, Bae J, Cho D, Jung S, Hwang J, et al. First description of programmed cell death10 (PDCD10) in rock bream (Oplegnathus fasciatus): Potential relations to the regulation of apoptosis by several pathogens. Dev Comp Immunol. 2016;55:51-5 pubmed publisher
    ..Generally, all of the examined tissues from the fish that were infected with Edwardsiella tarda and the red sea bream iridovirus (RSIV) exhibited significant up-regulations of RbPDCD10 expression compared ..
  80. Priyathilaka T, Kim Y, Udayantha H, Lee S, Herath H, Lakmal H, et al. Identification and molecular characterization of peroxiredoxin 6 from Japanese eel (Anguilla japonica) revealing its potent antioxidant properties and putative immune relevancy. Fish Shellfish Immunol. 2016;51:291-302 pubmed publisher
    ..Upon the immune challenges with Edwardsiella tarda, lipopolysaccharides and polyinosinic:polycytidylic acid, expression of AjPrdx6 mRNA transcripts were ..
  81. Lee W, Oh J, Kim E, Kang N, Kim K, Ahn G, et al. A prebiotic role of Ecklonia cava improves the mortality of Edwardsiella tarda-infected zebrafish models via regulating the growth of lactic acid bacteria and pathogen bacteria. Fish Shellfish Immunol. 2016;54:620-8 pubmed publisher
    ..100% ethanol extracts (ECE) showed the anti-bacterial activities on the fish pathogenic bacteria such as (Edwardsiella tarda; E. tarda, Streptococcus iniae; S. iniae, and Vibrio harveyi; V. harveyi)...
  82. Yasuike M, Nishiki I, Iwasaki Y, Nakamura Y, Fujiwara A, Sugaya E, et al. Full-genome sequence of a novel myovirus, GF-2, infecting Edwardsiella tarda: comparison with other Edwardsiella myoviral genomes. Arch Virol. 2015;160:2129-33 pubmed publisher
    Edwardsiellosis, which is caused by Edwardsiella tarda, a Gram-negative bacterium, is one of the most serious infectious diseases in both marine and freshwater fish farms worldwide...
  83. Du Y, Tang X, Sheng X, Xing J, Zhan W. The influence of concentration of inactivated Edwardsiella tarda bacterin and immersion time on antigen uptake and expression of immune-related genes in Japanese flounder (Paralichthys olivaceus). Microb Pathog. 2017;103:19-28 pubmed publisher
    ..that the immune response of Japanese flounder was associated with the concentration of formalin-inactivated Edwardsiella tarda and immersion time...
  84. Chu T, Huang Y, Hou M, Wang Q, Xiao J, Liu Q, et al. In Vivo Programmed Gene Expression Based on Artificial Quorum Networks. Appl Environ Microbiol. 2015;81:4984-92 pubmed publisher
    ..the araQS system was used to control the production of a heterologous protective antigen in an attenuated Edwardsiella tarda strain, which successfully evoked efficient immune protection in a fish model...
  85. Wang J, Sun L. Edwardsiella tarda-regulated proteins in Japanese flounder (Paralichthys olivaceus): Identification and evaluation of antibacterial potentials. J Proteomics. 2015;124:1-10 pubmed publisher
    b>Edwardsiella tarda is a severe aquaculture pathogen that infects a wide range of fish including Japanese flounder (Paralichthys olivaceus)...
  86. Jayaramu P, Tripathi G, Pavan Kumar A, Keezhedath J, Pathan M, Kurcheti P. Studies on expression pattern of toll-like receptor 5 (TLR5) in Edwardsiella tarda infected Pangasianodon hypophthalmus. Fish Shellfish Immunol. 2017;63:68-73 pubmed publisher
    ..soluble form) gene from Pangasianodon hypophthalmus and analysed its expression profile upon challenge by Edwardsiella tarda. Bioinformatic analysis of gene sequence revealed a putative protein of 266 amino acids with four Leucine ..
  87. Suezawa C, Yasuda M, Negayama K, Kameyama T, Hirauchi M, Nakai T, et al. Identification of genes associated with the penetration activity of the human type of Edwardsiella tarda EdwGII through human colon epithelial cell monolayers. Microb Pathog. 2016;95:148-156 pubmed publisher
    b>Edwardsiella tarda is a Gram-negative pathogen with a broad host range including fish and humans. E. tarda causes gastrointestinal and extraintestinal infections in humans. In present study, the penetration activities of 22 strains of E...
  88. Du Y, Tang X, Zhan W, Xing J, Sheng X. Immunoglobulin Tau Heavy Chain (IgT) in Flounder, Paralichthys olivaceus: Molecular Cloning, Characterization, and Expression Analyses. Int J Mol Sci. 2016;17: pubmed publisher
    ..After infection and vaccination with Edwardsiella tarda via intraperitoneal injection and immersion, the qRT-PCR analysis demonstrated that the IgT mRNA level was ..
  89. Liu X, Sun J, Wu H. Glycolysis-related proteins are broad spectrum vaccine candidates against aquacultural pathogens. Vaccine. 2017;35:3813-3816 pubmed publisher
    Reverse vaccinology (RV) has become a popular method for developing vaccines. Although Edwardsiella tarda is deemed to be an important fish pathogen, so far, no reports have used a genome-based approach to screen vaccine candidates ..
  90. Kim J, Kong H, Nam B, Park J, Kim D, Jeong J, et al. The first report of cathepsin A gene in a teleost (rock bream, Oplegnathus fasciatus): An investigation of immune functions upon infection with several pathogens. Dev Comp Immunol. 2017;76:262-267 pubmed publisher
    ..In general, all of the examined tissues that were infected with Edwardsiella tarda, Streptococcus iniae, or red sea bream iridovirus (RSIV) exhibited significant upregulation of RbCTSA ..
  91. Thulasitha W, Kim Y, Umasuthan N, Jayasooriya R, Kim G, Nam B, et al. Thioredoxin domain-containing protein 12 from Oplegnathus fasciatus: Molecular characterization, expression against immune stimuli, and biological activities related to oxidative stress. Fish Shellfish Immunol. 2016;54:11-21 pubmed publisher
    ..In comparison, injection of lipopolysaccharide, Edwardsiella tarda, Streptococcus iniae, polyinosinic:polycytidylic acid (poly[I:C]) and rock bream iridovirus mostly triggered ..
  92. Beck B, Song J, Park B, Kim D, Kwak J, Do H, et al. Distinct immune tones are established by Lactococcus lactis BFE920 and Lactobacillus plantarum FGL0001 in the gut of olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2016;55:434-43 pubmed publisher
    ..Furthermore, when orally challenged by Edwardsiella tarda, LL-fed flounder survived at a significantly higher rate than LP-fed fish...