Aspergillus nidulans FGSC A4

Summary

Alias: Emericella nidulans FGSC A4

Top Publications

  1. Wartenberg D, Vödisch M, Kniemeyer O, Albrecht Eckardt D, Scherlach K, Winkler R, et al. Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin. J Proteomics. 2012;75:4038-49 pubmed publisher
    ..nidulans and describe a farnesol-inducible dehydrin-like protein that contributes to the high tolerance of resting conidia against oxidative and heat stress...
  2. Sanchez J, Somoza A, Keller N, Wang C. Advances in Aspergillus secondary metabolite research in the post-genomic era. Nat Prod Rep. 2012;29:351-71 pubmed publisher
    ..Activating these pathways has been met with some success, but many more dormant genes remain to be awakened...
  3. Kosti V, Papageorgiou I, Diallinas G. Dynamic elements at both cytoplasmically and extracellularly facing sides of the UapA transporter selectively control the accessibility of substrates to their translocation pathway. J Mol Biol. 2010;397:1132-43 pubmed publisher
    ..Our results strongly suggest that distinct domains at both sides of UapA act as selective dynamic gates controlling substrate access to their translocation pathway...
  4. Amillis S, Kosti V, Pantazopoulou A, Mikros E, Diallinas G. Mutational analysis and modeling reveal functionally critical residues in transmembrane segments 1 and 3 of the UapA transporter. J Mol Biol. 2011;411:567-80 pubmed publisher
    ..Our results are in agreement with a topological model of UapA built on the recently published structure of UraA, a bacterial homolog of UapA...
  5. Dilokpimol A, Nakai H, Gotfredsen C, Baumann M, Nakai N, Abou Hachem M, et al. Recombinant production and characterisation of two related GH5 endo-β-1,4-mannanases from Aspergillus nidulans FGSC A4 showing distinctly different transglycosylation capacity. Biochim Biophys Acta. 2011;1814:1720-9 pubmed publisher
    The glycoside hydrolase family 5 (GH5) endo-β-1,4-mannanases ManA and ManC from Aspergillus nidulans FGSC A4 were produced in Pichia pastoris X33 and purified in high yields of 120 and 145mg/L, respectively, from the culture supernatants...
  6. Abenza J, Galindo A, Pinar M, Pantazopoulou A, de los Ríos V, Peñalva M. Endosomal maturation by Rab conversion in Aspergillus nidulans is coupled to dynein-mediated basipetal movement. Mol Biol Cell. 2012;23:1889-901 pubmed publisher
    ..Genetic studies establish that endosomal maturation is essential, whereas homotypic vacuolar fusion is not...
  7. Herv s Aguilar A, Rodr guez J, Tilburn J, Arst H, Pe alva M. Evidence for the direct involvement of the proteasome in the proteolytic processing of the Aspergillus nidulans zinc finger transcription factor PacC. J Biol Chem. 2007;282:34735-47 pubmed publisher
    ..Wild-type PacC(53) becomes multiply phosphorylated upon alkaline pH exposure. Processing-impaired 4K-->R PacC(53) becomes excessively phosphorylated...
  8. Zhang J, Yao X, Fischer L, Abenza J, Peñalva M, Xiang X. The p25 subunit of the dynactin complex is required for dynein-early endosome interaction. J Cell Biol. 2011;193:1245-55 pubmed publisher
    ..These results indicate that p25, in conjunction with the rest of the dynactin complex, is important for dynein-early endosome interaction. ..
  9. Zhang J, Wang L, Zhuang L, Huo L, Musa S, Li S, et al. Arp11 affects dynein-dynactin interaction and is essential for dynein function in Aspergillus nidulans. Traffic. 2008;9:1073-87 pubmed publisher
    ..We suggest that loss of the pointed-end proteins alters the Arp1 filament in a way that affects the conformation of p150 required for its proper interaction with the dynein motor. ..
  10. Hynes M, Murray S, Khew G, Davis M. Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans. Genetics. 2008;178:1355-69 pubmed publisher
    ..The mitochondrial pathway is not required for growth on valerate or for long-chain fatty acid utilization. ..

Detail Information

Publications63

  1. Wartenberg D, Vödisch M, Kniemeyer O, Albrecht Eckardt D, Scherlach K, Winkler R, et al. Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin. J Proteomics. 2012;75:4038-49 pubmed publisher
    ..nidulans and describe a farnesol-inducible dehydrin-like protein that contributes to the high tolerance of resting conidia against oxidative and heat stress...
  2. Sanchez J, Somoza A, Keller N, Wang C. Advances in Aspergillus secondary metabolite research in the post-genomic era. Nat Prod Rep. 2012;29:351-71 pubmed publisher
    ..Activating these pathways has been met with some success, but many more dormant genes remain to be awakened...
  3. Kosti V, Papageorgiou I, Diallinas G. Dynamic elements at both cytoplasmically and extracellularly facing sides of the UapA transporter selectively control the accessibility of substrates to their translocation pathway. J Mol Biol. 2010;397:1132-43 pubmed publisher
    ..Our results strongly suggest that distinct domains at both sides of UapA act as selective dynamic gates controlling substrate access to their translocation pathway...
  4. Amillis S, Kosti V, Pantazopoulou A, Mikros E, Diallinas G. Mutational analysis and modeling reveal functionally critical residues in transmembrane segments 1 and 3 of the UapA transporter. J Mol Biol. 2011;411:567-80 pubmed publisher
    ..Our results are in agreement with a topological model of UapA built on the recently published structure of UraA, a bacterial homolog of UapA...
  5. Dilokpimol A, Nakai H, Gotfredsen C, Baumann M, Nakai N, Abou Hachem M, et al. Recombinant production and characterisation of two related GH5 endo-β-1,4-mannanases from Aspergillus nidulans FGSC A4 showing distinctly different transglycosylation capacity. Biochim Biophys Acta. 2011;1814:1720-9 pubmed publisher
    The glycoside hydrolase family 5 (GH5) endo-β-1,4-mannanases ManA and ManC from Aspergillus nidulans FGSC A4 were produced in Pichia pastoris X33 and purified in high yields of 120 and 145mg/L, respectively, from the culture supernatants...
  6. Abenza J, Galindo A, Pinar M, Pantazopoulou A, de los Ríos V, Peñalva M. Endosomal maturation by Rab conversion in Aspergillus nidulans is coupled to dynein-mediated basipetal movement. Mol Biol Cell. 2012;23:1889-901 pubmed publisher
    ..Genetic studies establish that endosomal maturation is essential, whereas homotypic vacuolar fusion is not...
  7. Herv s Aguilar A, Rodr guez J, Tilburn J, Arst H, Pe alva M. Evidence for the direct involvement of the proteasome in the proteolytic processing of the Aspergillus nidulans zinc finger transcription factor PacC. J Biol Chem. 2007;282:34735-47 pubmed publisher
    ..Wild-type PacC(53) becomes multiply phosphorylated upon alkaline pH exposure. Processing-impaired 4K-->R PacC(53) becomes excessively phosphorylated...
  8. Zhang J, Yao X, Fischer L, Abenza J, Peñalva M, Xiang X. The p25 subunit of the dynactin complex is required for dynein-early endosome interaction. J Cell Biol. 2011;193:1245-55 pubmed publisher
    ..These results indicate that p25, in conjunction with the rest of the dynactin complex, is important for dynein-early endosome interaction. ..
  9. Zhang J, Wang L, Zhuang L, Huo L, Musa S, Li S, et al. Arp11 affects dynein-dynactin interaction and is essential for dynein function in Aspergillus nidulans. Traffic. 2008;9:1073-87 pubmed publisher
    ..We suggest that loss of the pointed-end proteins alters the Arp1 filament in a way that affects the conformation of p150 required for its proper interaction with the dynein motor. ..
  10. Hynes M, Murray S, Khew G, Davis M. Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans. Genetics. 2008;178:1355-69 pubmed publisher
    ..The mitochondrial pathway is not required for growth on valerate or for long-chain fatty acid utilization. ..
  11. Calcagno Pizarelli A, Negrete Urtasun S, Denison S, Rudnicka J, Bussink H, Múnera Huertas T, et al. Establishment of the ambient pH signaling complex in Aspergillus nidulans: PalI assists plasma membrane localization of PalH. Eukaryot Cell. 2007;6:2365-75 pubmed
    ....
  12. Eigentler A, Pocsi I, Marx F. The anisin1 gene encodes a defensin-like protein and supports the fitness of Aspergillus nidulans. Arch Microbiol. 2012;194:427-37 pubmed publisher
    ..We therefore conclude that the secreted protein Anisin1 contributes to the optimal development of A. nidulans and we further propose that it has a sensing/signaling function for elevated H(2)O(2) levels. ..
  13. Papageorgiou I, Gournas C, Vlanti A, Amillis S, Pantazopoulou A, Diallinas G. Specific interdomain synergy in the UapA transporter determines its unique specificity for uric acid among NAT carriers. J Mol Biol. 2008;382:1121-35 pubmed publisher
    ..We finally show that intramolecular synergy among UapA domains is highly specific and propose that it forms the basis for the evolution of the unique specificity of UapA for uric acid, a property not present in other NAT members. ..
  14. Hernández Rodríguez Y, Hastings S, Momany M. The septin AspB in Aspergillus nidulans forms bars and filaments and plays roles in growth emergence and conidiation. Eukaryot Cell. 2012;11:311-23 pubmed publisher
    ..AspE orthologs are only found in filamentous fungi, suggesting that this class of septins might be required for stability of septin bars and filaments in highly polar cells. ..
  15. Zhuang L, Zhang J, Xiang X. Point mutations in the stem region and the fourth AAA domain of cytoplasmic dynein heavy chain partially suppress the phenotype of NUDF/LIS1 loss in Aspergillus nidulans. Genetics. 2007;175:1185-96 pubmed
    ..The fact that a mutation in the end of AAA4 negatively regulates dynein's ATPase activity but partially compensates for NUDF loss indicates the importance of the AAA4 domain in dynein regulation in vivo. ..
  16. Krappmann S, Jung N, Medic B, Busch S, Prade R, Braus G. The Aspergillus nidulans F-box protein GrrA links SCF activity to meiosis. Mol Microbiol. 2006;61:76-88 pubmed
    ....
  17. Virag A, Harris S. Functional characterization of Aspergillus nidulans homologues of Saccharomyces cerevisiae Spa2 and Bud6. Eukaryot Cell. 2006;5:881-95 pubmed
    ..We propose that the core function of the polarisome in polarized growth is maintained but with different contributions of polarisome components to the process. ..
  18. Vlanti A, Amillis S, Koukaki M, Diallinas G. A novel-type substrate-selectivity filter and ER-exit determinants in the UapA purine transporter. J Mol Biol. 2006;357:808-19 pubmed
    ..The presence of any of the TMS12 tested was necessary for ER-exit while their specific amino acid composition affected the kinetics of chimeras. ..
  19. Son S, Osmani S. Analysis of all protein phosphatase genes in Aspergillus nidulans identifies a new mitotic regulator, fcp1. Eukaryot Cell. 2009;8:573-85 pubmed publisher
    ..The mitotic defects of the Anfcp1(ts) cdk1F double mutant suggests a previously unrealized function for AnFCP1 in regulating mitotic progression, perhaps counteracting Cdk1-mediated phosphorylation. ..
  20. Seo J, Guan Y, Yu J. FluG-dependent asexual development in Aspergillus nidulans occurs via derepression. Genetics. 2006;172:1535-44 pubmed
    ..Genetic analyses demonstrated that SfgA functions downstream of FluG but upstream of transcriptional activators (FlbD, FlbC, FlbB, and BrlA) necessary for normal conidiation. ..
  21. Nayak T, Edgerton Morgan H, Horio T, Xiong Y, De Souza C, Osmani S, et al. Gamma-tubulin regulates the anaphase-promoting complex/cyclosome during interphase. J Cell Biol. 2010;190:317-30 pubmed publisher
    ..Thus, gamma-tubulin functions to regulate this key mitotic and cell cycle regulatory complex. ..
  22. Koukaki M, Vlanti A, Goudela S, Pantazopoulou A, Gioule H, Tournaviti S, et al. The nucleobase-ascorbate transporter (NAT) signature motif in UapA defines the function of the purine translocation pathway. J Mol Biol. 2005;350:499-513 pubmed
    ..Our results show that the NAT signature motif defines the function of the UapA purine translocation pathway and strongly suggest that this might occur by determining the interactions of UapA with the imidazole part of purines. ..
  23. Wang J, Hu H, Wang S, Shi J, Chen S, Wei H, et al. The important role of actinin-like protein (AcnA) in cytokinesis and apical dominance of hyphal cells in Aspergillus nidulans. Microbiology. 2009;155:2714-25 pubmed publisher
    ..nidulans. This is the first report, to our knowledge, of the function of an actinin-like protein in filamentous fungi. ..
  24. Edgerton Morgan H, Oakley B. γ-Tubulin plays a key role in inactivating APC/C(Cdh1) at the G(1)-S boundary. J Cell Biol. 2012;198:785-91 pubmed publisher
    ....
  25. Govindaraghavan M, Lad A, Osmani S. The NIMA kinase is required to execute stage-specific mitotic functions after initiation of mitosis. Eukaryot Cell. 2014;13:99-109 pubmed publisher
    ..This study shows that NIMA is required not only for mitotic entry but also sequentially for successful completion of stage-specific mitotic events. ..
  26. McGrath A, Mithieux S, Collyer C, Bakhuis J, van den Berg M, Sein A, et al. Structure and activity of Aspergillus nidulans copper amine oxidase. Biochemistry. 2011;50:5718-30 pubmed publisher
    ..The active site is the most open of any of those of the structurally characterized enzymes in the family and provides a ready explanation for its lysine oxidase-like activity...
  27. Gournas C, Oestreicher N, Amillis S, Diallinas G, Scazzocchio C. Completing the purine utilisation pathway of Aspergillus nidulans. Fungal Genet Biol. 2011;48:840-8 pubmed publisher
    ..The identification of these additional genes confirms the complete absence of clustering of the genes involved in purine utilisation in A. nidulans...
  28. Wang C, Shim W, Shaw B. Aspergillus nidulans striatin (StrA) mediates sexual development and localizes to the endoplasmic reticulum. Fungal Genet Biol. 2010;47:789-99 pubmed publisher
    ..By co-labeling with FM4-64 and co-localization with nuclear localized StuA(NLS)::DsRed or CxnA (an endoplasmic reticulum marker), we determined that StrA mainly localizes to endoplasmic reticulum and the nuclear envelope...
  29. Kriangkripipat T, Momany M. Aspergillus nidulans protein O-mannosyltransferases play roles in cell wall integrity and developmental patterning. Eukaryot Cell. 2009;8:1475-85 pubmed publisher
    ..nidulans Pmts modify proteins in the cell wall integrity pathway. The altered developmental patterns in Deltapmt mutants suggest that A. nidulans Pmts modify proteins that serve as spatial cues...
  30. Maggio Hall L, Lyne P, Wolff J, Keller N. A single acyl-CoA dehydrogenase is required for catabolism of isoleucine, valine and short-chain fatty acids in Aspergillus nidulans. Fungal Genet Biol. 2008;45:180-9 pubmed publisher
    ....
  31. Fitzgibbon G, Morozov I, Jones M, Caddick M. Genetic analysis of the TOR pathway in Aspergillus nidulans. Eukaryot Cell. 2005;4:1595-8 pubmed publisher
    ..Unlike the situation in Saccharomyces cerevisiae, there is only a single Tor kinase, as in plant and animal systems, and mutant phenotypes suggest that the TOR pathway plays only a minor role in regulating nitrogen metabolism...
  32. Wang S, Cao J, Liu X, Hu H, Shi J, Zhang S, et al. Putative calcium channels CchA and MidA play the important roles in conidiation, hyphal polarity and cell wall components in Aspergillus nidulans. PLoS ONE. 2012;7:e46564 pubmed publisher
    ..Our findings suggest that the high-affinity Ca(2+) channel may represent a viable and completely unexplored avenue to reduce conidiation in the Aspergilli...
  33. Yao X, Wang X, Xiang X. FHIP and FTS proteins are critical for dynein-mediated transport of early endosomes in Aspergillus. Mol Biol Cell. 2014;25:2181-9 pubmed publisher
    ..However, in the absence of HookA or FtsA, FhipA protein level is significantly reduced. Our results indicate that all three proteins in the FtsA/HookA/FhipA complex are important for dynein-mediated early endosome movement...
  34. Fekete E, Karaffa L, Seiboth B, Fekete E, Kubicek C, Flipphi M. Identification of a permease gene involved in lactose utilisation in Aspergillus nidulans. Fungal Genet Biol. 2012;49:415-25 pubmed publisher
    ..The effect of lacpA gene deletion on lactose uptake was exacerbated at lower substrate concentrations, evidence for the existence of a second transport system with a lower affinity for this disaccharide in A. nidulans...
  35. Bromann K, Toivari M, Viljanen K, Vuoristo A, Ruohonen L, Nakari Set l T. Identification and characterization of a novel diterpene gene cluster in Aspergillus nidulans. PLoS ONE. 2012;7:e35450 pubmed publisher
    ..These results identify the first Aspergillus nidulans diterpene gene cluster and suggest a biosynthetic pathway for ent-pimara-8(14),15-diene...
  36. Ahuja M, Chiang Y, Chang S, Praseuth M, Entwistle R, Sanchez J, et al. Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans. J Am Chem Soc. 2012;134:8212-21 pubmed publisher
    ..This has allowed us to determine the products of eight NR-PKSs of Aspergillus nidulans, including seven novel compounds, as well as the NR-PKS genes required for the synthesis of the toxins alternariol (8) and cichorine (19)...
  37. Bayram z, Bayram z, Ahmed Y, Maruyama J, Valerius O, Rizzoli S, et al. The Aspergillus nidulans MAPK module AnSte11-Ste50-Ste7-Fus3 controls development and secondary metabolism. PLoS Genet. 2012;8:e1002816 pubmed publisher
    ..Our data suggest that not only Fus3, but even the entire MAPK module complex of four physically interacting proteins, can migrate from plasma membrane to nuclear envelope...
  38. Perales Clemente E, Bayona Bafaluy M, P rez Martos A, Barrientos A, Fern ndez Silva P, Enriquez J. Restoration of electron transport without proton pumping in mammalian mitochondria. Proc Natl Acad Sci U S A. 2008;105:18735-9 pubmed publisher
    ....
  39. Belaish R, Sharon H, Levdansky E, Greenstein S, Shadkchan Y, Osherov N. The Aspergillus nidulans cetA and calA genes are involved in conidial germination and cell wall morphogenesis. Fungal Genet Biol. 2008;45:232-42 pubmed publisher
    ..nidulans conidial germination. We show that CETA and CALA are secreted proteins that together play an essential role in early conidial germination...
  40. Bruggeman J, Debets A, Hoekstra R. Selection arena in Aspergillus nidulans. Fungal Genet Biol. 2004;41:181-8 pubmed
    ..The selection arena ensures that reproductive energy is invested mainly in dikaryons and thus sexual spores of good genetic quality...
  41. Bauer S, Vasu P, Mort A, Somerville C. Cloning, expression, and characterization of an oligoxyloglucan reducing end-specific xyloglucanobiohydrolase from Aspergillus nidulans. Carbohydr Res. 2005;340:2590-7 pubmed publisher
    ..The enzyme has a specific activity of 7 U/mg at the pH optimum of 3 and at the temperature optimum of 42 degrees C...
  42. Malavazi I, Semighini C, Kress M, Harris S, Goldman G. Regulation of hyphal morphogenesis and the DNA damage response by the Aspergillus nidulans ATM homolog AtmA. Genetics. 2006;173:99-109 pubmed publisher
    ..Our results suggest that AtmA regulates the function and/or localization of landmark proteins required for the formation of a polarity axis. We propose that a similar function may contribute to the establishment of neuronal polarity...
  43. Semighini C, Savoldi M, Goldman G, Harris S. Functional characterization of the putative Aspergillus nidulans poly(ADP-ribose) polymerase homolog PrpA. Genetics. 2006;173:87-98 pubmed publisher
    ..Collectively, our results provide a gateway for probing the diverse functions of PARP in a sophisticated microbial genetic system...
  44. Mogensen J, Nielsen H, Hofmann G, Nielsen J. Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol. Fungal Genet Biol. 2006;43:593-603 pubmed publisher
    ....
  45. Bernreiter A, Ramon A, Fern ndez Mart nez J, Berger H, Ara jo Bazan L, Espeso E, et al. Nuclear export of the transcription factor NirA is a regulatory checkpoint for nitrate induction in Aspergillus nidulans. Mol Cell Biol. 2007;27:791-802 pubmed publisher
    ....
  46. Oberegger H, Zadra I, Schoeser M, Abt B, Parson W, Haas H. Identification of members of the Aspergillus nidulans SREA regulon: genes involved in siderophore biosynthesis and utilization. Biochem Soc Trans. 2002;30:781-3 pubmed
    ..The functional characterization of these genes will help to unravel the pathways involved in siderophore biosynthesis and uptake...
  47. Gournas C, Amillis S, Vlanti A, Diallinas G. Transport-dependent endocytosis and turnover of a uric acid-xanthine permease. Mol Microbiol. 2010;75:246-60 pubmed publisher
    ..Finally, we demonstrate that in the presence of substrates, non-functional UapA versions can be endocytosed in trans if expressed in the simultaneous presence of active UapA versions, even if the latter cannot be endocytosed themselves...
  48. Kim Y, Nandakumar M, Marten M. Proteome map of Aspergillus nidulans during osmoadaptation. Fungal Genet Biol. 2007;44:886-95 pubmed publisher
    ..There also was an increased expression of heat shock proteins and Shp1-like protein degradation protein, implicating increased protein turnover. Five novel osmoadaptation proteins of unknown functions were also identified...
  49. Efimov V, Morris N. The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein. J Cell Biol. 2000;150:681-8 pubmed
    ..In addition, NUDF coprecipitates with an epitope-tagged NUDE. The fact that NUDF and LIS1 interact with the same protein domain strengthens the notion that these two proteins are functionally related...
  50. Paukstelis P, Lambowitz A. Identification and evolution of fungal mitochondrial tyrosyl-tRNA synthetases with group I intron splicing activity. Proc Natl Acad Sci U S A. 2008;105:6010-5 pubmed publisher
    ..The unique group I intron splicing activity of these fungal enzymes may provide a new target for antifungal drugs...
  51. Berger H, Basheer A, B ck S, Reyes Dominguez Y, Dalik T, Altmann F, et al. Dissecting individual steps of nitrogen transcription factor cooperation in the Aspergillus nidulans nitrate cluster. Mol Microbiol. 2008;69:1385-98 pubmed publisher
    ..Continuous nitrate assimilation leads to self-nitrogen metabolite repression but nitrate-activated NirA is partially compensating for lowered AreA activities under these conditions...
  52. Panagiotou G, Grotkjaer T, Hofmann G, Bapat P, Olsson L. Overexpression of a novel endogenous NADH kinase in Aspergillus nidulans enhances growth. Metab Eng. 2009;11:31-9 pubmed publisher
    ..This conclusion may impact the design of new strains capable of generating reducing power in the form of NADPH, which is crucial for efficient production of many industrially important metabolites and enzymes...
  53. Kinghorn J, Pateman J. Mutants of Aspergillus nidulans lacking nicotinamide adenine dinucleotide-specific glutamate dehydrogenase. J Bacteriol. 1976;125:42-7 pubmed
    ..The properties are described of the double mutants bearing the mutations gdhB1 and gdhA1 or tamA119, which have low NADP-GDH activity...
  54. Oestreicher N, Scazzocchio C. Phenotypes of mutations in the 5'-UTR of a limiting transcription factor in Aspergillus nidulans can be accounted for by translational inhibition and leaky scanning. Genetics. 2009;181:1261-72 pubmed publisher
    ..The first-AUG rule and the phenomena of translational inhibition and leaky scanning provide a coherent explanation of the results presented in this article...
  55. Bok J, Chiang Y, Szewczyk E, Reyes Dominguez Y, Davidson A, Sanchez J, et al. Chromatin-level regulation of biosynthetic gene clusters. Nat Chem Biol. 2009;5:462-4 pubmed publisher
    ..Modification of the chromatin landscape in fungal secondary metabolite clusters allows for a simple technological means to express silent fungal secondary metabolite gene clusters...
  56. De Groot P, Brandt B, Horiuchi H, Ram A, de Koster C, Klis F. Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans. Fungal Genet Biol. 2009;46 Suppl 1:S72-81 pubmed
    ..nidulans, including ten predicted GPI proteins, most of which belong to carbohydrate-active enzyme families that are also found in the walls of ascomycetous yeasts...
  57. Han S, Navarro J, Greve R, Adams T. Translational repression of brlA expression prevents premature development in Aspergillus. EMBO J. 1993;12:2449-57 pubmed
    ..Removing the microORF initiation codon leads to deregulated brlA expression, resulting in an inappropriate activation of development. We propose that one mechanism for developmental induction in A.nidulans involves translational control...
  58. Lee S, Shaw B. A novel interaction between N-myristoylation and the 26S proteasome during cell morphogenesis. Mol Microbiol. 2007;63:1039-53 pubmed publisher
    ..This is the first report linking N-myristoylation and ubiquitin-proteasome-dependent proteolysis during morphogenesis...
  59. Macios M, Caddick M, Weglenski P, Scazzocchio C, Dzikowska A. The GATA factors AREA and AREB together with the co-repressor NMRA, negatively regulate arginine catabolism in Aspergillus nidulans in response to nitrogen and carbon source. Fungal Genet Biol. 2012;49:189-98 pubmed publisher
    ..We therefore propose a novel function for NMRA, the modulation of AREA and AREB activity in response to the carbon status of the cell...
  60. Helmstaedt K, Laubinger K, Vosskuhl K, Bayram O, Busch S, Hoppert M, et al. The nuclear migration protein NUDF/LIS1 forms a complex with NUDC and BNFA at spindle pole bodies. Eukaryot Cell. 2008;7:1041-52 pubmed publisher
    ..These results show that the conserved NUDF and NUDC proteins play a concerted role at SPBs at different stages of the cell cycle and that NUDF recruits additional proteins specifically to the dynein complex at SPBs...
  61. Shimizu M, Fujii T, Masuo S, Takaya N. Mechanism of de novo branched-chain amino acid synthesis as an alternative electron sink in hypoxic Aspergillus nidulans cells. Appl Environ Microbiol. 2010;76:1507-15 pubmed publisher
    ..These indicated that hypoxic branched-chain amino acid synthesis is a unique alternative mechanism that functions in the absence of glucose-to-ethanol/lactate fermentation and oxygen respiration...
  62. Andrade A, Van Nistelrooy J, Peery R, Skatrud P, De Waard M. The role of ABC transporters from Aspergillus nidulans in protection against cytotoxic agents and in antibiotic production. Mol Gen Genet. 2000;263:966-77 pubmed
    ..These results suggest that ABC transporters may be involved in secretion of penicillin from fungal cells...
  63. Heimel K, Freitag J, Hampel M, Ast J, B lker M, K mper J. Crosstalk between the unfolded protein response and pathways that regulate pathogenic development in Ustilago maydis. Plant Cell. 2013;25:4262-77 pubmed publisher
    ..Crosstalk between UPR and the b mating-type regulated developmental program adapts ER homeostasis to the changing demands during biotrophy...