Experts and Doctors on swine in Sweden

Summary

Locale: Sweden
Topic: swine

Top Publications

  1. Amarger V, Nguyen M, Van Laere A, Braunschweig M, Nezer C, Georges M, et al. Comparative sequence analysis of the INS-IGF2-H19 gene cluster in pigs. Mamm Genome. 2002;13:388-98 pubmed
    ..The high GC and CpG content were more pronounced in the pig than in the two other species. The results will facilitate the further characterization of this important QTL in the pig. ..
  2. Gong F, Jemth P, Escobar Galvis M, Vlodavsky I, Horner A, Lindahl U, et al. Processing of macromolecular heparin by heparanase. J Biol Chem. 2003;278:35152-8 pubmed
    ..These findings strongly suggest that the intracellular processing of the heparin proteoglycan polysaccharide chains is catalyzed by heparanase, which primarily cleaves target structures distinct from the antithrombin-binding sequence. ..
  3. Zoric M, Sjolund M, Persson M, Nilsson E, Lundeheim N, Wallgren P. Lameness in piglets. Abrasions in nursing piglets and transfer of protection towards infections with Streptococci from sow to offspring. J Vet Med B Infect Dis Vet Public Health. 2004;51:278-84 pubmed
    ..During the first 2 weeks of life somewhat lower median levels of serum antibodies were recorded among the piglets that were treated against arthritis (n = 8)...
  4. Jacobson M, Aspan A, Königsson M, Segerstad C, Wallgren P, Fellström C, et al. Routine diagnostics of Lawsonia intracellularis performed by PCR, serological and post mortem examination, with special emphasis on sample preparation methods for PCR. Vet Microbiol. 2004;102:189-201 pubmed
    ..To determine the presence of the bacteria in a herd, serology or repeated faecal sampling for PCR from target animals, or both, should be used...
  5. Råsbäck T, Fellström C, Bergsjø B, Cizek A, Collin K, Gunnarsson A, et al. Assessment of diagnostics and antimicrobial susceptibility testing of Brachyspira species using a ring test. Vet Microbiol. 2005;109:229-43 pubmed
    ..The diversity of the results highlights the importance of ring tests for a high quality of diagnostics and antimicrobial susceptibility tests for Brachyspira spp. This is the first ring test described for Brachyspira spp...
  6. Eriste E, Norberg A, Nepomuceno D, Kuei C, Kamme F, Tran D, et al. A novel form of neurotensin post-translationally modified by arginylation. J Biol Chem. 2005;280:35089-97 pubmed
    ..We have shown that SK-N-SH neuroblastoma cells express NTR1 and NTR3 but not NTR2, suggesting that the Ca2+ mobilization elicited by R-NT is via NTR1. ..
  7. Törnkvist A, Sjöberg P, Markides K, Bergquist J. Analysis of catecholamines and related substances using porous graphitic carbon as separation media in liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;801:323-9 pubmed
    ..The developed strategy was applied for analysis of brain tissue, i.e. a substantia nigra (ns) sample. ..
  8. Hosseinpour F, Ellfolk M, Norlin M, Wikvall K. Phenobarbital suppresses vitamin D3 25-hydroxylase expression: a potential new mechanism for drug-induced osteomalacia. Biochem Biophys Res Commun. 2007;357:603-7 pubmed
    ..A downregulation of 25-hydroxylation by phenobarbital may explain, at least in part, the increased risk of osteomalacia, bone loss, and fractures in long-term phenobarbital therapy...
  9. Baner J, Gyarmati P, Yacoub A, Hakhverdyan M, Stenberg J, Ericsson O, et al. Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes. J Virol Methods. 2007;143:200-6 pubmed
    ..The results were in complete agreement with identities and serotypes determined previously. This novel virus detection method is discussed in terms of usefulness and further development...
  10. Razdan P, Tummaruk P, Kindahl H, Rodriguez Martinez H, Hultén F, Einarsson S. The impact of induced stress during days 13 and 14 of pregnancy on the composition of allantoic fluid and conceptus development in sows. Theriogenology. 2004;61:757-67 pubmed
    ..It is, therefore, suggested that P4 influences the placenta size among food-deprived sows...

Detail Information

Publications62

  1. Amarger V, Nguyen M, Van Laere A, Braunschweig M, Nezer C, Georges M, et al. Comparative sequence analysis of the INS-IGF2-H19 gene cluster in pigs. Mamm Genome. 2002;13:388-98 pubmed
    ..The high GC and CpG content were more pronounced in the pig than in the two other species. The results will facilitate the further characterization of this important QTL in the pig. ..
  2. Gong F, Jemth P, Escobar Galvis M, Vlodavsky I, Horner A, Lindahl U, et al. Processing of macromolecular heparin by heparanase. J Biol Chem. 2003;278:35152-8 pubmed
    ..These findings strongly suggest that the intracellular processing of the heparin proteoglycan polysaccharide chains is catalyzed by heparanase, which primarily cleaves target structures distinct from the antithrombin-binding sequence. ..
  3. Zoric M, Sjolund M, Persson M, Nilsson E, Lundeheim N, Wallgren P. Lameness in piglets. Abrasions in nursing piglets and transfer of protection towards infections with Streptococci from sow to offspring. J Vet Med B Infect Dis Vet Public Health. 2004;51:278-84 pubmed
    ..During the first 2 weeks of life somewhat lower median levels of serum antibodies were recorded among the piglets that were treated against arthritis (n = 8)...
  4. Jacobson M, Aspan A, Königsson M, Segerstad C, Wallgren P, Fellström C, et al. Routine diagnostics of Lawsonia intracellularis performed by PCR, serological and post mortem examination, with special emphasis on sample preparation methods for PCR. Vet Microbiol. 2004;102:189-201 pubmed
    ..To determine the presence of the bacteria in a herd, serology or repeated faecal sampling for PCR from target animals, or both, should be used...
  5. Råsbäck T, Fellström C, Bergsjø B, Cizek A, Collin K, Gunnarsson A, et al. Assessment of diagnostics and antimicrobial susceptibility testing of Brachyspira species using a ring test. Vet Microbiol. 2005;109:229-43 pubmed
    ..The diversity of the results highlights the importance of ring tests for a high quality of diagnostics and antimicrobial susceptibility tests for Brachyspira spp. This is the first ring test described for Brachyspira spp...
  6. Eriste E, Norberg A, Nepomuceno D, Kuei C, Kamme F, Tran D, et al. A novel form of neurotensin post-translationally modified by arginylation. J Biol Chem. 2005;280:35089-97 pubmed
    ..We have shown that SK-N-SH neuroblastoma cells express NTR1 and NTR3 but not NTR2, suggesting that the Ca2+ mobilization elicited by R-NT is via NTR1. ..
  7. Törnkvist A, Sjöberg P, Markides K, Bergquist J. Analysis of catecholamines and related substances using porous graphitic carbon as separation media in liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;801:323-9 pubmed
    ..The developed strategy was applied for analysis of brain tissue, i.e. a substantia nigra (ns) sample. ..
  8. Hosseinpour F, Ellfolk M, Norlin M, Wikvall K. Phenobarbital suppresses vitamin D3 25-hydroxylase expression: a potential new mechanism for drug-induced osteomalacia. Biochem Biophys Res Commun. 2007;357:603-7 pubmed
    ..A downregulation of 25-hydroxylation by phenobarbital may explain, at least in part, the increased risk of osteomalacia, bone loss, and fractures in long-term phenobarbital therapy...
  9. Baner J, Gyarmati P, Yacoub A, Hakhverdyan M, Stenberg J, Ericsson O, et al. Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes. J Virol Methods. 2007;143:200-6 pubmed
    ..The results were in complete agreement with identities and serotypes determined previously. This novel virus detection method is discussed in terms of usefulness and further development...
  10. Razdan P, Tummaruk P, Kindahl H, Rodriguez Martinez H, Hultén F, Einarsson S. The impact of induced stress during days 13 and 14 of pregnancy on the composition of allantoic fluid and conceptus development in sows. Theriogenology. 2004;61:757-67 pubmed
    ..It is, therefore, suggested that P4 influences the placenta size among food-deprived sows...
  11. Ljungvall K, Veeramachaneni D, Hou M, Hultén F, Magnusson U. Morphology and morphometry of the reproductive organs in prepubertal and postpubertal male pigs exposed to di(2-ethylhexyl) phthalate before puberty: Precocious development of bulbourethral glands. Theriogenology. 2008;70:984-91 pubmed publisher
    ..05) in DEHP-treated boars. Collectively, these features indicate that adolescent exposure to DEHP induces precocious maturity of bulbourethral glands in pigs with persistent effects lasting into adulthood...
  12. Jansson D, Fellström C, Johansson K. Intestinal spirochetes isolated from wild-living jackdaws, hooded crows and rooks (genus Corvus): provisionally designated "Brachyspira corvi" sp. nov. Anaerobe. 2008;14:287-95 pubmed publisher
    ..L gen. n. corvi, of a crow)...
  13. Jurek A, Amagasaki K, Gembarska A, Heldin C, Lennartsson J. Negative and positive regulation of MAPK phosphatase 3 controls platelet-derived growth factor-induced Erk activation. J Biol Chem. 2009;284:4626-34 pubmed publisher
    ..In conclusion, MKP3 is an important regulator of PDGF-induced Erk phosphorylation acting in both a rapid positive feed-forward and a later negative feed-back loop. ..
  14. Cai D, Yuan M, Jia Y, Liu H, Hu Y, Zhao R. Maternal gestational betaine supplementation-mediated suppression of hepatic cyclin D2 and presenilin1 gene in newborn piglets is associated with epigenetic regulation of the STAT3-dependent pathway. J Nutr Biochem. 2015;26:1622-31 pubmed publisher
    ..These neonatal changes in cell cycle and proliferation regulation may lead to lower liver weight and hepatic DNA content at weaning. ..
  15. Lundell K. The porcine taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21) gene: evolution by gene duplication and gene conversion. Biochem J. 2004;378:1053-8 pubmed
    ....
  16. Lundell K, Wikvall K. Gene structure of pig sterol 12alpha-hydroxylase (CYP8B1) and expression in fetal liver: comparison with expression of taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21). Biochim Biophys Acta. 2003;1634:86-96 pubmed
    ..Both CYP8B1 and the key enzyme in hyocholic acid formation, taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21), were found to be expressed in pig liver in a developmental-dependent but opposite fashion. ..
  17. Alvarez Fernandez M, Liang Y, Abrahamson M, Su X. Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile. J Biol Chem. 2005;280:18221-8 pubmed
    ....
  18. Axen E, Bergman T, Wikvall K. Purification and characterization of a vitamin D3 25-hydroxylase from pig liver microsomes. Biochem J. 1992;287 ( Pt 3):725-31 pubmed
    ..The results of the present study show that the pig appears to be a representative species for evaluation of vitamin D3 hydroxylases in other mammals, including man. ..
  19. Masson K, Heiss E, Band H, Ronnstrand L. Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation. Biochem J. 2006;399:59-67 pubmed
    ..Taken together, our findings reveal novel insights into the mechanisms by which Cbl negatively regulates c-Kit-mediated signalling. ..
  20. Lindblad M. Microbiological sampling of swine carcasses: a comparison of data obtained by swabbing with medical gauze and data collected routinely by excision at Swedish abattoirs. Int J Food Microbiol. 2007;118:180-5 pubmed
    ..For monitoring of low numbers of Enterobacteriaceae and E. coli, like those found on swine carcasses at Swedish abattoirs, the results also show that swabbing of a relatively large area is superior to excision of a smaller area. ..
  21. Råsbäck T, Johansson K, Jansson D, Fellström C, Alikhani M, La T, et al. Development of a multilocus sequence typing scheme for intestinal spirochaetes within the genus Brachyspira. Microbiology. 2007;153:4074-87 pubmed
    ..This is a first step towards establishing an MLST system for use in identifying Brachyspira species and determining relationships between individual strains and species in the genus. ..
  22. Chew M, Hawthorne W, Bendall J, Whereat S, Huang S, Ting I, et al. No beneficial effects of levosimendan in acute porcine endotoxaemia. Acta Anaesthesiol Scand. 2011;55:851-61 pubmed publisher
    ..Hyperlactataemia, acidosis and increases in plasma pro-inflammatory cytokines were observed, the mechanisms and implications of which remain unclear. ..
  23. Stenqvist O, Grivans C, Andersson B, Lundin S. Lung elastance and transpulmonary pressure can be determined without using oesophageal pressure measurements. Acta Anaesthesiol Scand. 2012;56:738-47 pubmed publisher
    ..The aim of the present study was to demonstrate that lung elastance and transpulmonary pressure can be determined without using oesophageal pressure measurements...
  24. Fornstedt B, Bergh I, Rosengren E, Carlsson A. An improved HPLC-electrochemical detection method for measuring brain levels of 5-S-cysteinyldopamine, 5-S-cysteinyl-3,4-dihydroxyphenylalanine, and 5-S-cysteinyl-3,4-dihydroxyphenylacetic acid. J Neurochem. 1990;54:578-86 pubmed
    ..The products generated during catechol autoxidation, including quinones and reduced forms of oxygen, are known to be potentially cytotoxic...
  25. Sorby M, Sandstrom J, Ostman A. An extracellular ligand increases the specific activity of the receptor-like protein tyrosine phosphatase DEP-1. Oncogene. 2001;20:5219-24 pubmed
    ..These experiments identify Matrigel as a source of DEP-1 agonist(s) and provide the first evidence for upregulation of the specific activity of receptor-like protein tyrosine phosphatases by extracellular ligands. ..
  26. Zhao Y, Kacskovics I, Zhao Z, Hammarstrom L. Presence of the di-leucine motif in the cytoplasmic tail of the pig FcRn alpha chain. Vet Immunol Immunopathol. 2003;96:229-33 pubmed
    ....
  27. Ito N, Wernstedt C, Engstrom U, Claesson Welsh L. Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules. J Biol Chem. 1998;273:23410-8 pubmed
    ..These results indicate that a spectrum of already known as well as novel phosphotyrosine-binding molecules are involved in signal transduction by Flt-1. ..
  28. Agerberth B, Gunne H, Odeberg J, Kogner P, Boman H, Gudmundsson G. FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. Proc Natl Acad Sci U S A. 1995;92:195-9 pubmed
    ..RNA blot analyses disclosed that the gene for FALL-39 is expressed mainly in human bone marrow and testis. ..
  29. Waltenberger J, Claesson Welsh L, Siegbahn A, Shibuya M, Heldin C. Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem. 1994;269:26988-95 pubmed
    ..e. in the presence of Flt1. This difference could possibly be explained by the formation of heterodimeric complexes between KDR and Flt1, or other molecules, in HUVE cells. ..
  30. Ruusala A, Aspenstrom P. The atypical Rho GTPase Wrch1 collaborates with the nonreceptor tyrosine kinases Pyk2 and Src in regulating cytoskeletal dynamics. Mol Cell Biol. 2008;28:1802-14 pubmed
    ..We propose a model in which Pyk2 and Src function to coordinate the Wrch1-dependent effects on cytoskeletal dynamics. ..
  31. Andersson L. Studying phenotypic evolution in domestic animals: a walk in the footsteps of Charles Darwin. Cold Spring Harb Symp Quant Biol. 2009;74:319-25 pubmed publisher
    ..In a recent study, we have identified the IGF2 repressor, and this previously unknown protein, named ZBED6, is specific for placental mammals and derived from a domesticated DNA transposon...
  32. Engström J, Hedenstierna G, Larsson A. Pharyngeal oxygen administration increases the time to serious desaturation at intubation in acute lung injury: an experimental study. Crit Care. 2010;14:R93 pubmed publisher
    ....
  33. Wierup N, Björkqvist M, Weström B, Pierzynowski S, Sundler F, Sjolund K. Ghrelin and motilin are cosecreted from a prominent endocrine cell population in the small intestine. J Clin Endocrinol Metab. 2007;92:3573-81 pubmed
    ..The likely cosecretion of intestinal ghrelin and motilin suggests concerted actions of the two hormones. These data may have implications for understanding gut motility and clinical implications for dysmotility and bariatric surgery. ..
  34. Bergstrom M, Lu L, Fasth K, Wu F, Bergström Pettermann E, Tolmachev V, et al. In vitro and animal validation of bromine-76-bromodeoxyuridine as a proliferation marker. J Nucl Med. 1998;39:1273-9 pubmed
    ..The potential of 76Br-bromodeoxyuridine as a PET tracer for characterizing proliferation potential was investigated in multicellular tumor aggregates and in healthy rats and pigs...
  35. Pettersson H, Lundqvist J, Norlin M. Effects of CYP7B1-mediated catalysis on estrogen receptor activation. Biochim Biophys Acta. 2010;1801:1090-7 pubmed publisher
    ....
  36. Belikov S, Astrand C, Wrange O. Mechanism of histone H1-stimulated glucocorticoid receptor DNA binding in vivo. Mol Cell Biol. 2007;27:2398-410 pubmed
    ..These effects results in increased concentration of free GR and, hence, in increased GR-GRE binding...
  37. Ellfolk M, Norlin M, Wikvall K. Isolation and properties of the CYP2D25 promoter: transcriptional regulation by vitamin D3 metabolites. Biochem Biophys Res Commun. 2006;345:568-72 pubmed
    ..The data suggest that VDR-mediated inhibition of 25-hydroxylase(s) by vitamin D3 metabolites at the transcriptional level may play an important role in the regulation of 25-hydroxyvitamin D3 production in liver and other tissues. ..
  38. Norlin M, Andersson U, Bjorkhem I, Wikvall K. Oxysterol 7 alpha-hydroxylase activity by cholesterol 7 alpha-hydroxylase (CYP7A). J Biol Chem. 2000;275:34046-53 pubmed
    ..These findings may have implications for oxysterol-mediated regulation of gene expression and for pathways of bile acid biosynthesis. A possible use of 20(S)-hydroxycholesterol as a marker substrate for CYP7A is proposed. ..
  39. Salaneck E, Holmberg S, Berglund M, Boswell T, Larhammar D. Chicken neuropeptide Y receptor Y2: structural and pharmacological differences to mammalian Y2(1). FEBS Lett. 2000;484:229-34 pubmed
    ....
  40. Molin G, Soderlind O, Ursing J, Nørrung V, Ternström A, Löwenhielm C. Occurrence of Erysipelothrix rhusiopathiae on pork and in pig slurry, and the distribution of specific antibodies in abattoir workers. J Appl Bacteriol. 1989;67:347-52 pubmed
    ..In 20 of 138 workers antibodies against E. rhusiopathiae were found; 14 had increased levels of IgG antibodies, seven had increased levels of IgM antibodies and one had an increased level of both...
  41. Pettersson E, Ljunggren E, Morrison D, Mattsson J. Functional analysis and localisation of a delta-class glutathione S-transferase from Sarcoptes scabiei. Int J Parasitol. 2005;35:39-48 pubmed
    ..Additionally, the polyclonal sera raised against recombinant S. scabiei glutathione S-transferase readily detected a protein from mites, corresponding to the predicted size of native glutathione S-transferase. ..
  42. Steen S, Sjoberg T, Liao Q, Bozovic G, Wohlfart B. Pharmacological normalization of circulation after acute brain death. Acta Anaesthesiol Scand. 2012;56:1006-12 pubmed publisher
    ..The aim was to show that the circulation can be normalized pharmacologically for 24 h in pigs after total removal of the brain and brainstem by decapitation (between C2 and C3)...
  43. Benktander J, Angstrom J, Breimer M, Teneberg S. Redefinition of the carbohydrate binding specificity of Helicobacter pylori BabA adhesin. J Biol Chem. 2012;287:31712-24 pubmed publisher
    ..The binding of BabA to the two sets of isoreceptors is due to conformational similarities of the terminal disaccharides of H type 1 and Globo H and of the terminal trisaccharides of A type 1 and Globo A...
  44. Tienthai P, Kimura N, Heldin P, Sato E, Rodriguez Martinez H. Expression of hyaluronan synthase-3 in porcine oviducal epithelium during oestrus. Reprod Fertil Dev. 2003;15:99-105 pubmed
    ....
  45. Fedulova N, Raffalli Mathieu F, Mannervik B. Characterization of porcine alpha-class glutathione transferase A1-1. Arch Biochem Biophys. 2011;507:205-11 pubmed publisher
    ..Differences in the H-site residues of mammalian Alpha-class GSTs may explain the catalytic divergence. ..
  46. Enerback S, Bjursell G. Genomic organization of the region encoding guinea pig lipoprotein lipase; evidence for exon fusion and unconventional splicing. Gene. 1989;84:391-7 pubmed
    ....
  47. Ghosh F, Johansson K. Neuronal and glial alterations in complex long-term rhegmatogenous retinal detachment. Curr Eye Res. 2012;37:704-11 pubmed publisher
    ..The findings may be important when devising surgical strategies to avoid permanent retinal detachment. ..
  48. Timmusk S, Merlot E, Lövgren T, Järvekülg L, Berg M, Fossum C. Regulator of G protein signalling 16 is a target for a porcine circovirus type 2 protein. J Gen Virol. 2009;90:2425-36 pubmed publisher
    ..Furthermore, poRGS16 appeared to participate in the translocation of the ORF3 protein into the cell nucleus, suggesting that the observed interaction may play an important role in the infection biology of porcine circovirus. ..
  49. Sjolund M, de la Fuente A, Fossum C, Wallgren P. Responses of pigs to a re-challenge with Actinobacillus pleuropneumoniae after being treated with different antimicrobials following their initial exposure. Vet Rec. 2009;164:550-5 pubmed
    ..The previously uninoculated control group and the enrofloxacin-treated group developed severe disease, but the three seropositive groups remained unaffected...
  50. Johansson J, Gudmundsson G, Rottenberg M, Berndt K, Agerberth B. Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37. J Biol Chem. 1998;273:3718-24 pubmed
    ..However, in the presence of human serum, the antibacterial and the cytotoxic activities of LL-37 are inhibited. ..
  51. Landgren E, Blume Jensen P, Courtneidge S, Claesson Welsh L. Fibroblast growth factor receptor-1 regulation of Src family kinases. Oncogene. 1995;10:2027-35 pubmed
    ..Moreover, inhibition of PKC attenuated the bFGF induced decrease in autophosphorylation of Src family members. These data indicate a negative regulatory role for PKC on Src kinase activity in certain cell types. ..
  52. Mattsson S, Wallgren P. Phenotyping of E. coli serotypes associated to oedema disease. Acta Vet Scand. 2008;50:13 pubmed publisher
    ..It is caused by E. coli strains that express fimbriae F18 and produce verotoxin 2e, mainly belonging to serotype O138, O139 or O141. The aim of this study was to compare E. coli isolates within these serotypes with respect to diversity...
  53. Kask K, Berthold M, Kahl U, Nordvall G, Bartfai T. Delineation of the peptide binding site of the human galanin receptor. EMBO J. 1996;15:236-44 pubmed
    ..interacts with the Zn2+ sensitive pair of His264 and His267 of transmembrane domain VI, and Tyr9 of galanin interacts with Phe282 of transmembrane domain VII, while the C-terminus of galanin is pointing towards the N-terminus of th ..
  54. Blomström A, Hakhverdyan M, Reid S, Dukes J, King D, Belak S, et al. A one-step reverse transcriptase loop-mediated isothermal amplification assay for simple and rapid detection of swine vesicular disease virus. J Virol Methods. 2008;147:188-93 pubmed
    ....
  55. Kimme P, Ledin T, Sjoberg F. Dose effect of sevoflurane and isoflurane anesthetics on cortical blood flow during controlled hypotension in the pig. Acta Anaesthesiol Scand. 2007;51:607-13 pubmed
    ..3-1.2) or propofol (10 mg x kg(-1)x h(-1))]. In this aspect (cortical tissue perspective), these volatile agents appear as suitable as propofol for neurosurgical anesthesia for patients at risk. ..
  56. Lennartsson J, Wardega P, Engstrom U, Hellman U, Heldin C. Alix facilitates the interaction between c-Cbl and platelet-derived growth factor beta-receptor and thereby modulates receptor down-regulation. J Biol Chem. 2006;281:39152-8 pubmed
    ..Our data suggest that Alix inhibits down-regulation of PDGFRbeta by modulating the interaction between c-Cbl and the receptor, thereby affecting the ubiquitination of the receptor. ..
  57. Marklund S, Kijas J, Rodriguez Martinez H, Ronnstrand L, Funa K, Moller M, et al. Molecular basis for the dominant white phenotype in the domestic pig. Genome Res. 1998;8:826-33 pubmed
    ..The EMBL accession numbers for porcine KIT1*0101, KIT1*0202, KIT2*0202, and KIT2*0101 are AJ223228-AJ223231, respectively.] ..
  58. Kijas J, Moller M, Plastow G, Andersson L. A frameshift mutation in MC1R and a high frequency of somatic reversions cause black spotting in pigs. Genetics. 2001;158:779-85 pubmed
    ..In several breeds of pigs the phenotypic manifestation of this allele has been modified by selection for or against black spots. ..
  59. Siegbahn A, Johnell M, Sorensen B, Petersen L, Heldin C. Regulation of chemotaxis by the cytoplasmic domain of tissue factor. Thromb Haemost. 2005;93:27-34 pubmed
    ..We conclude that the cytoplasmic domain of TF plays a pivotal role in modulating cellular migration response. Our results suggest that the FVIIa/TF complex mediates intracellular signaling by alternative signal transduction pathway(s). ..
  60. Rivera E, Daggfeldt A, Hu S. Ginseng extract in aluminium hydroxide adjuvanted vaccines improves the antibody response of pigs to porcine parvovirus and Erysipelothrix rhusiopathiae. Vet Immunol Immunopathol. 2003;91:19-27 pubmed
    ..Thus, the use of ginseng as a co-adjuvant provides a simple, safe and cheap alternative for improving the potency of aluminium hydroxide adjuvanted vaccines...
  61. Johansson E, Domeika K, Berg M, Alm G, Fossum C. Characterisation of porcine monocyte-derived dendritic cells according to their cytokine profile. Vet Immunol Immunopathol. 2003;91:183-97 pubmed
    ..The addition of IFN-alpha during differentiation of DC in GM-CSF and IL-4 enhanced their ability to stimulate allogeneic and syngeneic MLR, but did not alter their ability to produce cytokines. ..
  62. Van Laere A, Nguyen M, Braunschweig M, Nezer C, Collette C, Moreau L, et al. A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig. Nature. 2003;425:832-6 pubmed
    ..The result supports the long-held view that regulatory mutations are important for controlling phenotypic variation. ..