Experts and Doctors on base sequence in United States


Locale: United States
Topic: base sequence

Top Publications

  1. Speiser D, Ortiz D, Kreppel L, Scheel G, McDonald G, Ow D. Purine biosynthetic genes are required for cadmium tolerance in Schizosaccharomyces pombe. Mol Cell Biol. 1992;12:5301-10 pubmed
    ..pombe, and perhaps in other biological systems. ..
  2. Robishaw J, Kalman V, Moomaw C, Slaughter C. Existence of two gamma subunits of the G proteins in brain. J Biol Chem. 1989;264:15758-61 pubmed
    ..Also, evidence is presented, demonstrating the existence of a second, structurally distinct, form of the gamma subunit of Gs, Gi, and Go in brain. ..
  3. Myers R, Payson R, Chotani M, Deaven L, Chiu I. Gene structure and differential expression of acidic fibroblast growth factor mRNA: identification and distribution of four different transcripts. Oncogene. 1993;8:341-9 pubmed
    ..The sequences upstream of the start sites for aFGF 1.B mRNA do not contain a consensus TATA box. In contrast, the canonical CCAAT and TATA sequences are located at the proper distances from the transcription start site of aFGF 1.A mRNA. ..
  4. Malik N, Haugen H, Modrell B, Shoyab M, Clegg C. Developmental abnormalities in mice transgenic for bovine oncostatin M. Mol Cell Biol. 1995;15:2349-58 pubmed
    ..Information regarding bovine oncostatin M may help characterize the structure and function of this cytokine in other vertebrate species. ..
  5. Yang Q, Paskind M, Bolger G, Thompson W, Repaske D, Cutler L, et al. A novel cyclic GMP stimulated phosphodiesterase from rat brain. Biochem Biophys Res Commun. 1994;205:1850-8 pubmed
    ..The cGSPDE cDNA we have isolated and that of Sonnenburg et al. represent alternatively spliced mRNA products from the same gene, with the brain isoform designed to be targeted to membranes. ..
  6. Abhayawardhane Y, Stewart G. Bacillus subtilis possesses a second determinant with extensive sequence similarity to the Escherichia coli mreB morphogene. J Bacteriol. 1995;177:765-73 pubmed
    ..A second site mutation, designated som-1, was mapped to the hisA-mbl region of the chromosome by transduction. ..
  7. Klein R, Silos Santiago I, Smeyne R, Lira S, Brambilla R, Bryant S, et al. Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements. Nature. 1994;368:249-51 pubmed
    ..These mice display abnormal movements and postures, indicating that NT3/TrkC-dependent sensor; neurons may play a primary role in proprioception, the sense of position and movement of the limbs. ..
  8. Kavanaugh M, Wang H, Zhang Z, Zhang W, Wu Y, Dechant E, et al. Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family. J Biol Chem. 1994;269:15445-50 pubmed
    ..These results demonstrate that domains of these transporters can function in chimeric combinations to control viral receptor and transport functions. ..
  9. Lin T, Young W, Chang C. Multiple functions of the TR2-11 orphan receptor in modulating activation of two key cis-acting elements involved in the retinoic acid signal transduction system. J Biol Chem. 1995;270:30121-8 pubmed
    ..Together, our data suggest that the TR2 orphan receptor may be a master regulator in modulating the activation of two key HREs, RARE beta and CRBPIIp, involved in the retinoic acid signal transduction pathway. ..

More Information

Publications550 found, 100 shown here

  1. Parthun M, Widom J, Gottschling D. The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism. Cell. 1996;87:85-94 pubmed
    ..We propose that the Hat2p/Rbap48 family serve as escorts of histone metabolism enzymes to facilitate their interaction with histone H4. ..
  2. Pollenz R, Sullivan H, Holmes J, Necela B, Peterson R. Isolation and expression of cDNAs from rainbow trout (Oncorhynchus mykiss) that encode two novel basic helix-loop-Helix/PER-ARNT-SIM (bHLH/PAS) proteins with distinct functions in the presence of the aryl hydrocarbon receptor. Evidence for alternativ. J Biol Chem. 1996;271:30886-96 pubmed
    ..AHR complexes to DNA. In addition, the presence of rtARNTa can reduce the aryl hydrocarbon receptor-dependent function of rtARNTb in vivo and in vitro. ..
  3. Kimmel Jehan C, DeLuca H. Cloning of the mouse 25-hydroxyvitamin D(3)-1alpha-hydroxylase (CYP1alpha) gene. Biochim Biophys Acta. 2000;1475:109-13 pubmed
    ..This molecular cloning makes possible the generation of transgenic mice in order to further investigate the role and importance of the 25-hydroxyvitamin D(3)-1alpha-hydroxylase (CYP1alpha). ..
  4. Dai G, Wang D, Liu B, Kasik J, Muller H, White R, et al. Three novel paralogs of the rodent prolactin gene family. J Endocrinol. 2000;166:63-75 pubmed
    ..Future experimentation is needed to determine the specific roles of each of these ligands in the biology of pregnancy. ..
  5. Gilinger G, Bellofatto V. Trypanosome spliced leader RNA genes contain the first identified RNA polymerase II gene promoter in these organisms. Nucleic Acids Res. 2001;29:1556-64 pubmed
    ..We show here that the in vitro transcription extract contains a binding activity that is specific for the initiator element and thus may participate in recruiting RNA polymerase II to the SL RNA gene promoter. ..
  6. Holmes W, Appling D. Cloning and characterization of methenyltetrahydrofolate synthetase from Saccharomyces cerevisiae. J Biol Chem. 2002;277:20205-13 pubmed
    ..Growth phenotypes of multiply disrupted strains are consistent with a regulatory role for 5-CHO-THF in one-carbon metabolism and additionally suggest a metabolic interaction between the purine and methionine pathways. ..
  7. Zhou X, Hampel H, Roggenbuck J, Saba N, Prior T, Eng C. A 39-bp deletion polymorphism in PTEN in African American individuals: implications for molecular diagnostic testing. J Mol Diagn. 2002;4:114-7 pubmed
    ..Due to its location immediately upstream of the splicing site of exon 8, this polymorphism could be mistaken for a deleterious mutation in the PTEN. ..
  8. Nomaguchi M, Ackermann M, Yon C, You S, Padmanabhan R, Padmanbhan R. De novo synthesis of negative-strand RNA by Dengue virus RNA-dependent RNA polymerase in vitro: nucleotide, primer, and template parameters. J Virol. 2003;77:8831-42 pubmed
  9. Zou Y, Shell S, Utzat C, Luo C, Yang Z, Geacintov N, et al. Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease. Biochemistry. 2003;42:12654-61 pubmed
    ..The structure-function relationships in the recognition of the DNA lesions, based on our results, have been discussed. ..
  10. Tong S, Liss A, You M, Bose H. The activation of TC10, a Rho small GTPase, contributes to v-Rel-mediated transformation. Oncogene. 2007;26:2318-29 pubmed
    ..These results indicate that elevated TC10 activity contributes to v-Rel-mediated transformation of CEFs and demonstrate for the first time that a Rho factor alone is capable of inducing the in vitro transformation of primary cells. ..
  11. Holmes S, Scarpinato K, McCulloch S, Schaaper R, Kunkel T. Specialized mismatch repair function of Glu339 in the Phe-X-Glu motif of yeast Msh6. DNA Repair (Amst). 2007;6:293-303 pubmed
  12. Murphy E, Payne S. RyhB, an iron-responsive small RNA molecule, regulates Shigella dysenteriae virulence. Infect Immun. 2007;75:3470-7 pubmed
    ..Regulation of virB by RyhB implicates iron as an environmental factor contributing to the complex regulation of Shigella virulence determinants. ..
  13. Alkan C, Ventura M, Archidiacono N, Rocchi M, Sahinalp S, Eichler E. Organization and evolution of primate centromeric DNA from whole-genome shotgun sequence data. PLoS Comput Biol. 2007;3:1807-18 pubmed
    ..Our results confirm fundamental differences in the dispersal and evolution of centromeric satellites in the Old World monkey and ape lineages of evolution. ..
  14. Townsend H, Jha B, Silverman R, Barton D. A putative loop E motif and an H-H kissing loop interaction are conserved and functional features in a group C enterovirus RNA that inhibits ribonuclease L. RNA Biol. 2008;5:263-72 pubmed
    ..We conclude that a putative loop E motif and an H-H kissing loop interaction are key features of the group C enterovirus RNA associated with the inhibition of RNase L. ..
  15. Huff J, Pavlenok M, Sukumaran S, Niederweis M. Functions of the periplasmic loop of the porin MspA from Mycobacterium smegmatis. J Biol Chem. 2009;284:10223-31 pubmed publisher
    ..This is the first study identifying a molecular determinant of solute translocation in a mycobacterial porin...
  16. Valdivia C, Medeiros Domingo A, Ye B, Shen W, Algiers T, Ackerman M, et al. Loss-of-function mutation of the SCN3B-encoded sodium channel {beta}3 subunit associated with a case of idiopathic ventricular fibrillation. Cardiovasc Res. 2010;86:392-400 pubmed publisher
    ..This study provides molecular and cellular evidence implicating mutations in Navbeta3 as a cause of IVF. ..
  17. Galperin E, Abdelmoti L, Sorkin A. Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells. PLoS ONE. 2012;7:e36469 pubmed publisher
  18. Strotman L, O Connell R, Casavant B, Berry S, Sperger J, Lang J, et al. Selective nucleic acid removal via exclusion (SNARE): capturing mRNA and DNA from a single sample. Anal Chem. 2013;85:9764-70 pubmed publisher
  19. Dube S, Saksena N, Spicer T, Healey J, Benz P, Dube D, et al. Delayed seroconversion to STLV-1 infection is associated with mutations in the pol and rex genes. Virol J. 2013;10:282 pubmed publisher
    ..Simian T-cell lymphoma/leukemia virus-1 (STLV-1) infection of non-human primates can serve as a model for human T-cell lymphoma/leukemia virus infection...
  20. Sharma A, Haque F, Pi F, Shlyakhtenko L, Evers B, Guo P. Controllable self-assembly of RNA dendrimers. Nanomedicine. 2016;12:835-844 pubmed publisher
    ..The addition of folate also allowed recognition and subsequent binding to tumor cells. This new construct may prove to be useful in many clinical settings. ..
  21. Post T, Liszewski M, Adams E, Tedja I, Miller E, Atkinson J. Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype. J Exp Med. 1991;174:93-102 pubmed
    ..The expression in a single cell of four distinct protein species with variable STP-rich regions and cytoplasmic tails represents an interesting example of the use of alternative splicing to provide variability in a mammalian protein. ..
  22. Uehara H, Ebersole T, Bennett D, Artzt K. Submegabase clusters of unstable tandem repeats unique to the Tla region of mouse t haplotypes. Genetics. 1990;126:1093-102 pubmed
    ..Apart from the diagnostic relevance to t haplotypes, evolutionary and functional significances are discussed with respect to chromosome structure and genetic recombination. ..
  23. Rafalski J, Falco S. Structure of the yeast HOM3 gene which encodes aspartokinase. J Biol Chem. 1988;263:2146-51 pubmed
    ..However, no increase in aspartokinase mRNA is observed under general control derepressing conditions. ..
  24. Dangel A, Shen L, Mendoza A, Wu L, Yu C. Human helicase gene SKI2W in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene SKI2 and to the human gene KIAA0052: emergence of a new gene family. Nucleic Acids Res. 1995;23:2120-6 pubmed
  25. Kim Y, Francisco L, Chen G, Marcotte E, Chan C. Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J Cell Biol. 1994;127:1381-94 pubmed
    ..These genetic interactions together suggest that protein phosphorylation and dephosphorylation play an important role in the BEM2-mediated process of polarized cell growth. ..
  26. Hou Q, Gorski J. Estrogen receptor and progesterone receptor genes are expressed differentially in mouse embryos during preimplantation development. Proc Natl Acad Sci U S A. 1993;90:9460-4 pubmed
    ..These results provide a basis for determining the direct role of estrogen and progesterone in preimplantation embryos. ..
  27. Jackson J, Lopes J. The yeast UME6 gene is required for both negative and positive transcriptional regulation of phospholipid biosynthetic gene expression. Nucleic Acids Res. 1996;24:1322-9 pubmed
    ..Therefore, the UME6 gene has both a negative and a positive role in regulating phospholipid biosynthesis. ..
  28. Parks C, Shenk T. The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Sp1. J Biol Chem. 1996;271:4417-30 pubmed
    ..This initiator sequence differs from previously characterized initiators and may represent a new class of this transcriptional control sequence. ..
  29. Klesert T, Otten A, Bird T, Tapscott S. Trinucleotide repeat expansion at the myotonic dystrophy locus reduces expression of DMAHP. Nat Genet. 1997;16:402-6 pubmed
    ..Together, these results demonstrate that CTG-repeat expansions can suppress local gene expression and implicate DMAHP in DM pathogenesis. ..
  30. Fyodorov D, Nelson T, Deneris E. Pet-1, a novel ETS domain factor that can activate neuronal nAchR gene transcription. J Neurobiol. 1998;34:151-63 pubmed
    ..Our results lead us to hypothesize that Pet-1 acts as a transcriptional regulator of downstream target genes involved in cholinergic neurotransmission. ..
  31. Gupta A, Drazba J, Banerjee A. Specific interaction of heterogeneous nuclear ribonucleoprotein particle U with the leader RNA sequence of vesicular stomatitis virus. J Virol. 1998;72:8532-40 pubmed
    ..These results strongly suggest that hnRNP U plays an important role in the life cycle of VSV. ..
  32. Brenner M, Johnson A, Boespflug Tanguy O, Rodriguez D, Goldman J, Messing A. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet. 2001;27:117-20 pubmed
    ..Alexander disease therefore represents the first example of a primary genetic disorder of astrocytes, one of the major cell types in the vertebrate CNS. ..
  33. Mao C, Xu R, Szulc Z, Bielawska A, Galadari S, Obeid L. Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide. J Biol Chem. 2001;276:26577-88 pubmed
    ..Together, these data demonstrate that aPHC is a novel human alkaline phytoceramidase, the first mammalian alkaline ceramidase to be identified as being specific for the hydrolysis of phytoceramide. ..
  34. Hogema B, Gupta M, Senephansiri H, Burlingame T, Taylor M, Jakobs C, et al. Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase. Nat Genet. 2001;29:212-6 pubmed
    ..These findings provide insight into pathomechanisms and may have therapeutic relevance for the human SSADH deficiency disease and GHB overdose and toxicity. ..
  35. Sangwan I, O Brian M. Identification of a soybean protein that interacts with GAGA element dinucleotide repeat DNA. Plant Physiol. 2002;129:1788-94 pubmed publisher
    ..Homologs of GBP were found in other dicots and in the monocot rice (Oryza sativa), as well. We suggest that interaction between GAGA elements and GBP-like proteins is a regulatory feature in plants...
  36. Carbone G, McGuffie E, Collier A, Catapano C. Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplex-forming oligonucleotide. Nucleic Acids Res. 2003;31:833-43 pubmed
    ..This anti-transcriptional approach may be useful to examine the effects of selective downregulation of Ets2 expression and may have therapeutic applications. ..
  37. Schraw T, Lemons P, Dean W, Whiteheart S. A role for Sec1/Munc18 proteins in platelet exocytosis. Biochem J. 2003;374:207-17 pubmed publisher
    ..These studies demonstrate a clear role for SM proteins in platelet exocytosis and aggregation and suggest a dominant role for Munc18c in all three granule-release events...
  38. Ding H, Han C, Gibson D Ambrosio R, Steele V, D Ambrosio S. Piroxicam selectively inhibits the growth of premalignant and malignant human oral cell lines by limiting their progression through the S phase and reducing the levels of cyclins and AP-1. Int J Cancer. 2003;107:830-6 pubmed
  39. Li R, Lindholm K, Yang L, Yue X, Citron M, Yan R, et al. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients. Proc Natl Acad Sci U S A. 2004;101:3632-7 pubmed
  40. Nabokina S, Said H. Characterization of the 5'-regulatory region of the human thiamin transporter SLC19A3: in vitro and in vivo studies. Am J Physiol Gastrointest Liver Physiol. 2004;287:G822-9 pubmed
    ..These studies report the first characterization of the SLC19A3 promoter in vitro and in vivo and demonstrate the importance of an SP1 cis-regulatory element in regulating promoter activity of this important human gene. ..
  41. Slattery M, Liko D, Heideman W. The function and properties of the Azf1 transcriptional regulator change with growth conditions in Saccharomyces cerevisiae. Eukaryot Cell. 2006;5:313-20 pubmed
    ..Glucose produces conditions that destabilize the Azf1 protein, a finding that may reflect a glucose-induced change in Azf1 tertiary or quaternary structure. ..
  42. Lee P, Nam J, Davidson E. Exclusive developmental functions of gatae cis-regulatory modules in the Strongylocentrorus purpuratus embryo. Dev Biol. 2007;307:434-45 pubmed publisher
    ..In addition, they imply a functional cis-regulatory module exclusion, whereby only a single module can associate with the basal promoter and drive gene expression at any given time...
  43. Chang Y, Stockinger M, Tashiro H, Lin C. A novel noncoding RNA rescues mutant SOD1-mediated cell death. FASEB J. 2008;22:691-702 pubmed
    ..Searching the database of GenBank revealed that a large number of expressed sequence tag (EST) clones contain large portions of rRNA sequence, potentially indicating a heretofore overlooked class of mRNAs with functional significance. ..
  44. Zhang H, Muders M, Li J, Rinaldo F, Tindall D, Datta K. Loss of NKX3.1 favors vascular endothelial growth factor-C expression in prostate cancer. Cancer Res. 2008;68:8770-8 pubmed publisher
    ..Therefore, regulation of VEGF-C expression by NKX3.1 provides a possible mechanism by which the loss of NKX3.1 protein level leads to lymphangiogenesis in the late stages of advanced prostate cancer. ..
  45. Sud N, Kumar S, Wedgwood S, Black S. Modulation of PKCdelta signaling alters the shear stress-mediated increases in endothelial nitric oxide synthase transcription: role of STAT3. Am J Physiol Lung Cell Mol Physiol. 2009;296:L519-26 pubmed publisher
    ..In conclusion, shear decreases PKCdelta activity and, subsequently, reduces STAT3 binding to the eNOS promoter. This signaling pathway plays a previously unidentified role in the regulation of eNOS expression by shear stress. ..
  46. Tian L, Hou C, Tian K, Holcomb N, Gu L, Li G. Mismatch recognition protein MutSbeta does not hijack (CAG)n hairpin repair in vitro. J Biol Chem. 2009;284:20452-6 pubmed publisher
    ..Evidence presented here provides a novel view as to whether or not MutSbeta is involved in CAG repeat instability in humans. ..
  47. Lindner D, Banik M. Intragenomic variation in the ITS rDNA region obscures phylogenetic relationships and inflates estimates of operational taxonomic units in genus Laetiporus. Mycologia. 2011;103:731-40 pubmed publisher
    ..The use of cloned rDNA sequences might be problematic in fungal phylogenetic analyses, as well as in fungal bar-coding initiatives and efforts to detect fungal pathogens in environmental samples. ..
  48. Bai X, Sinha Datta U, Ko N, Bellon M, Nicot C. Nuclear export and expression of human T-cell leukemia virus type 1 tax/rex mRNA are RxRE/Rex dependent. J Virol. 2012;86:4559-65 pubmed publisher
    ..Our results shed light on HTLV-1 replication and reveal a more complex regulatory network than previously anticipated. ..
  49. Gunaratna R, Jiang H. A comprehensive analysis of the Manduca sexta immunotranscriptome. Dev Comp Immunol. 2013;39:388-98 pubmed publisher
    ..We identified most members of the putative Toll, IMD, MAPK-JNK-p38 and JAK-STAT pathways and small changes in their mRNA levels. Together, these findings set the stage for on-going analysis of the M. sexta immunogenome. ..
  50. Turk E, Das V, Seibert R, Andrulis E. The mitochondrial RNA landscape of Saccharomyces cerevisiae. PLoS ONE. 2013;8:e78105 pubmed publisher
    ..A clean and marker-less chromosomal deletion of the Dis3p MTS results in a defect in the decay of intron and mirror RNAs, thus revealing a role for Dis3p in mitochondrial RNA decay. ..
  51. Stanton B, Nielsen A, Tamsir A, Clancy K, Peterson T, Voigt C. Genomic mining of prokaryotic repressors for orthogonal logic gates. Nat Chem Biol. 2014;10:99-105 pubmed publisher
    ..This represents a large set of compatible gates that can be used to construct user-defined circuits. ..
  52. Jones K, Shapero M, Chevrette M, Fournier R. Subtractive hybridization cloning of a tissue-specific extinguisher: TSE1 encodes a regulatory subunit of protein kinase A. Cell. 1991;66:861-72 pubmed
    ..We conclude that TSE1 encodes a regulatory subunit of protein kinase A whose activity differs in different cell types. ..
  53. Wolf J, David V, Deutch A. Identification of a distal regulatory element in the 5' flanking region of the bovine prolactin gene. Nucleic Acids Res. 1990;18:4905-12 pubmed
    ..5 kb from the rat prolactin transcription initiation site. Deletion analysis of the enhancer region shows that sequences -1124 to -985 are necessary and sufficient for enhancer activity. ..
  54. Metz R, Bannister A, Sutherland J, Hagemeier C, O Rourke E, Cook A, et al. c-Fos-induced activation of a TATA-box-containing promoter involves direct contact with TATA-box-binding protein. Mol Cell Biol. 1994;14:6021-9 pubmed
    ..Since TBP binding is not exhibited by Fra-1, TBP-mediated activation may be one characteristic that discriminates the function of Fos-related proteins. ..
  55. Grompe M, Al Dhalimy M, Finegold M, Ou C, Burlingame T, Kennaway N, et al. Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice. Genes Dev. 1993;7:2298-307 pubmed
    ..We conclude that the neonatal lethal and liver dysfunction phenotype of the alf/hsdr-1 deletion is entirely attributable to loss of Fah. ..
  56. Popham D, Setlow P. Cloning, nucleotide sequence, and regulation of the Bacillus subtilis pbpE operon, which codes for penicillin-binding protein 4* and an apparent amino acid racemase. J Bacteriol. 1993;175:2917-25 pubmed
    ..This induction depended on the activity of the spo0A product in relieving repression by the abrB repressor. A single transcription start site which was apparently dependent on E sigma A was detected upstream of pbpE. ..
  57. Kalcheva I, Matsuda Y, Plass C, Chapman V. Isolation and characterization of a pseudoautosomal region-specific genetic marker in C57BL/6 mice using genomic representational difference analysis. Proc Natl Acad Sci U S A. 1995;92:12352-6 pubmed
    ..Preliminary analyses of recombination between the distal X chromosome gene amelogenin (Amg) and the PAR loci for either TelXY or sex chromosome association (Sxa) suggest that the locus DXYRp1 maps to the distal portion of the PAR. ..
  58. Lamian V, Small G, Feldherr C. Evidence for the existence of a novel mechanism for the nuclear import of Hsc70. Exp Cell Res. 1996;228:84-91 pubmed
    ..The novel signal has not been identified, but we have obtained evidence that it is located in the amino terminus of hsc70. ..
  59. Wilson P, Borisy G. Maternally expressed gamma Tub37CD in Drosophila is differentially required for female meiosis and embryonic mitosis. Dev Biol. 1998;199:273-90 pubmed
  60. Tasheva E, Funderburgh M, McReynolds J, Funderburgh J, Conrad G. The bovine mimecan gene. Molecular cloning and characterization of two major RNA transcripts generated by alternative use of two splice acceptor sites in the third exon. J Biol Chem. 1999;274:18693-701 pubmed
    ..We demonstrated that their expression is differentially modulated in a temporal manner by basic fibroblast growth factor. ..
  61. Tailor C, Willett B, Kabat D. A putative cell surface receptor for anemia-inducing feline leukemia virus subgroup C is a member of a transporter superfamily. J Virol. 1999;73:6500-5 pubmed
    ..These results suggest that the targeted destruction of erythroblasts by FeLV-C may derive from their greater sensitivity to this virus rather than from a preferential susceptibility to infection...
  62. Sakamoto T, Inoue Sakamoto K, Bryant D. A novel nitrate/nitrite permease in the marine Cyanobacterium synechococcus sp. strain PCC 7002. J Bacteriol. 1999;181:7363-72 pubmed
    ..The discovery of a nitrate/nitrite permease in Synechococcus sp. strain PCC 7002 suggests that significant differences in nutrient transporters may occur in marine and freshwater cyanobacteria. ..
  63. Siddiqui A, Stanley C, Berk S. Cloning and expression of isocitrate lyase from human round worm Strongyloides stercoralis. Parasite. 2000;7:233-6 pubmed
    ..The role of isocitrate lyase in the glyoxylate cycle and energy metabolism of S. stercoralis is also discussed. ..
  64. Sinha S, Abraham S, Gronostajski R, Campbell C. Differential DNA binding and transcription modulation by three T-box proteins, T, TBX1 and TBX2. Gene. 2000;258:15-29 pubmed
    ..These results suggest that the various T-box proteins, while highly conserved, likely use different mechanisms to modulate transcription and may have different targets in vivo. ..
  65. Papa C, Springer N, Muszynski M, Meeley R, Kaeppler S. Maize chromomethylase Zea methyltransferase2 is required for CpNpG methylation. Plant Cell. 2001;13:1919-28 pubmed
    ..No reductions in methylation were observed at CpG or asymmetric sites in heterozygous or homozygous mutant plants. Our research shows that chromomethylase Zmet2 is required for in vivo methylation of CpNpG sequences. ..
  66. Keith L, Bender C. Genetic divergence in the algT-muc operon controlling alginate biosynthesis and response to environmental stress in Pseudomonas syringae. DNA Seq. 2001;12:125-9 pubmed
    ..syringae revealed a unique arrangement when compared to other bacteria and lacked a mucC homologue. The relative importance of the mucC gene in the algT (rpoE) operon of various bacterial species is discussed. ..
  67. Mukherjee D, Gao M, O Connor J, Raijmakers R, Pruijn G, Lutz C, et al. The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements. EMBO J. 2002;21:165-74 pubmed
    ..Finally, PM-Scl75 protein was found to interact specifically with AREs. These data suggest that the interaction between the exosome and AREs plays a key role in regulating the efficiency of ARE-containing mRNA turnover. ..
  68. Gorski J, Liu F, Artigues A, Castagna L, Osdoby P. New alternatively spliced form of galectin-3, a member of the beta-galactoside-binding animal lectin family, contains a predicted transmembrane-spanning domain and a leucine zipper motif. J Biol Chem. 2002;277:18840-8 pubmed
    ..Gal-3TM1 is the first example of a galectin superfamily member capable of being expressed as a soluble protein and as a transmembrane protein. ..
  69. Matsui Y, Chansky H, Barahmand Pour F, Zielinska Kwiatkowska A, Tsumaki N, Myoui A, et al. COL11A2 collagen gene transcription is differentially regulated by EWS/ERG sarcoma fusion protein and wild-type ERG. J Biol Chem. 2003;278:11369-75 pubmed
    ..Taken together, these findings indicate that the COL11A2 gene is regulated both by potential ERG association with a histone deacetylase complex and by direct EWS/ERG recruitment of RNA polymerase II. ..
  70. Wang Y, Wang Y. Structure elucidation of DNA interstrand cross-link by a combination of nuclease P1 digestion with mass spectrometry. Anal Chem. 2003;75:6306-13 pubmed
    ..We believe that the method described in this paper can be generally applicable for investigating the structures of other DNA ICLs. ..
  71. Zou Y, Ma H, Minko I, Shell S, Yang Z, Qu Y, et al. DNA damage recognition of mutated forms of UvrB proteins in nucleotide excision repair. Biochemistry. 2004;43:4196-205 pubmed
    ..Our results suggest that Y92 may function differently with these two types of adducts, while the Y95 residue plays an unique role in stabilizing the interaction of UvrB with DNA damage, most likely by a hydrophobic stacking. ..
  72. Liu H, Zeng Y, Landes C, Kim Y, Zhu Y, Ma X, et al. Insights on the role of nucleic acid/protein interactions in chaperoned nucleic acid rearrangements of HIV-1 reverse transcription. Proc Natl Acad Sci U S A. 2007;104:5261-7 pubmed
    ..The data further indicate that the nucleation of annealing occurs in an encounter complex that is formed by two hairpins with one or both of the hairpins in the "Y" conformation. ..
  73. Khaladkar M, Liu J, Wen D, Wang J, Tian B. Mining small RNA structure elements in untranslated regions of human and mouse mRNAs using structure-based alignment. BMC Genomics. 2008;9:189 pubmed publisher
    ..Our result indicates that there may exist many conserved stem-loop structures in mammalian UTRs that are involved in coordinate post-transcriptional regulation of biological pathways. ..
  74. Zhang H, Stavnezer E. Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3. J Biol Chem. 2009;284:2867-79 pubmed publisher
    ..Our results indicate that Ski is necessary for muscle terminal differentiation and that it exerts this role, at least in part, through its association with Six1 and Eya3 to regulate the Myog transcription. ..
  75. Palmenberg A, Spiro D, Kuzmickas R, Wang S, Djikeng A, Rathe J, et al. Sequencing and analyses of all known human rhinovirus genomes reveal structure and evolution. Science. 2009;324:55-9 pubmed publisher
    ..The data density from complete sequences of the reference HRVs provided high resolution for this degree of modeling and serves as a platform for full genome-based epidemiologic studies and antiviral or vaccine development. ..
  76. Abler L, Mansour S, Sun X. Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung. Dev Dyn. 2009;238:1999-2013 pubmed publisher
    ..Our results indicate that both Fgf10 and Fgfr2 are required for a normal branching program and for proper proximal-distal patterning of the lung. ..
  77. Li F, Tian L, Gu L, Li G. Evidence that nucleosomes inhibit mismatch repair in eukaryotic cells. J Biol Chem. 2009;284:33056-61 pubmed publisher
    ..These findings suggest that nucleosomes may inhibit MMR in eukaryotic cells. The implications of these findings for our understanding of eukaryotic MMR are discussed...
  78. Liang F, Cho B. Enthalpy-entropy contribution to carcinogen-induced DNA conformational heterogeneity. Biochemistry. 2010;49:259-66 pubmed publisher
    ..6 cal mol(-1) K(-1) in favor of the intercalated S conformer. These findings demonstrate that the favorable entropy of the S conformer over B conformer determines the S/B population ratios at physiological temperatures. ..
  79. Mehraein Ghomi F, Basu H, Church D, Hoffmann F, Wilding G. Androgen receptor requires JunD as a coactivator to switch on an oxidative stress generation pathway in prostate cancer cells. Cancer Res. 2010;70:4560-8 pubmed publisher
  80. Hynes T, Yost E, Yost S, Berlot C. Multicolor BiFC analysis of G protein ?? complex formation and localization. Methods Mol Biol. 2011;756:229-43 pubmed publisher
    ..Methods are described for imaging and quantifying the internalization of pairs of ?? complexes in response to GPCR stimulation in living cells. ..
  81. Yoo M, Wendel J. Comparative evolutionary and developmental dynamics of the cotton (Gossypium hirsutum) fiber transcriptome. PLoS Genet. 2014;10:e1004073 pubmed publisher
  82. Carr D, Stofko Hahn R, Fraser I, Cone R, Scott J. Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79. J Biol Chem. 1992;267:16816-23 pubmed
    ..We propose that AKAP 79 and AKAP 150 function to anchor the type II PKA to the PSD, presumably for a role in the regulation of postsynaptic events. ..
  83. Shu H, Pelley R, Kung H. Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential. Proc Natl Acad Sci U S A. 1990;87:9103-7 pubmed
    ..To our knowledge, this is the first demonstration of a point mutation in the ATP-binding pocket that activates a tyrosine kinase. ..
  84. Lehn D, Moran S, MacDonald M. The sequence of the rat pyruvate carboxylase-encoding cDNA. Gene. 1995;165:331-2 pubmed
    ..The rat cDNAs open reading frame encodes a protein of 1178 amino acids that is 98.6% identical (99.0% similar) to that of mouse PC and 96.0% identical (97.8% similar) to that of human PC. ..
  85. Porter J, Messer A. Genetic mapping of farnesyltransferase alpha(Fnta) to mouse chromosome 8. Mamm Genome. 1996;7:622-3 pubmed
  86. Stallings Mann M, Ludwiczak R, Klinger K, Rottman F. Alternative splicing of exon 3 of the human growth hormone receptor is the result of an unusual genetic polymorphism. Proc Natl Acad Sci U S A. 1996;93:12394-9 pubmed
  87. de Koker T, Mozuch M, Cullen D, Gaskell J, Kersten P. Isolation and purification of pyranose 2-oxidase from Phanerochaete chrysosporium and characterization of gene structure and regulation. Appl Environ Microbiol. 2004;70:5794-800 pubmed
    ..This regulation pattern is similar to that observed for lignin peroxidases, manganese peroxidases, and glyoxal oxidase of P. chrysosporium, supporting evidence that POX has a role in lignocellulose degradation...
  88. Whitfield A, Rotenberg D, Aritua V, Hogenhout S. Analysis of expressed sequence tags from Maize mosaic rhabdovirus-infected gut tissues of Peregrinus maidis reveals the presence of key components of insect innate immunity. Insect Mol Biol. 2011;20:225-42 pubmed publisher
    ..This EST analysis sheds new light on immune response pathways in hemipteran guts that will be useful for further dissecting innate defence response pathways to rhabdovirus infection...
  89. Larson T, Kendra D, Busman M, Brown D. Fusarium verticillioides chitin synthases CHS5 and CHS7 are required for normal growth and pathogenicity. Curr Genet. 2011;57:177-89 pubmed publisher
    ..Our results demonstrate that both CHS5 and CHS7 are necessary for proper hyphal growth and pathogenicity of F. verticillioides on maize. ..
  90. Griffin T, Lau K, Chuang D. Characterization and conservation of the inner E2 core domain structure of branched-chain alpha-keto acid dehydrogenase complex from bovine liver. Construction of a cDNA encoding the entire transacylase (E2b) precursor. J Biol Chem. 1988;263:14008-14 pubmed
    ..coli E2k). These similarities suggest that these E2 proteins are structurally and evolutionarily related. ..
  91. Boronenkov I, Anderson R. The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases. J Biol Chem. 1995;270:2881-4 pubmed
    ..Surprisingly, the sequence of this PIP5K has no homology to known PtdIns kinases or protein kinases. However, the PIP5K is homologous to the Saccharomyces cerevisiae proteins Fab1p and Mss4p. ..
  92. Tokumitsu H, Brickey D, Glod J, Hidaka H, Sikela J, Soderling T. Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase. J Biol Chem. 1994;269:28640-7 pubmed
    ..Sun, P., Brickey, D., Soderling, S. H., Klamo, E., and Soderling, T.R. (1994) J. Biol. Chem. 269, 15520-15527). ..