Experts and Doctors on base sequence in Japan

Summary

Locale: Japan
Topic: base sequence

Top Publications

  1. Tokuue Y, Goto S, Imamura M, Obinata T, Masaki T, Endo T. Transfection of chicken skeletal muscle alpha-actinin cDNA into nonmuscle and myogenic cells: dimerization is not essential for alpha-actinin to bind to microfilaments. Exp Cell Res. 1991;197:158-67 pubmed
    ..Thus, dimer formation is not essential for alpha-actinin molecules to bind to microfilaments. ..
  2. Watanabe M, Ando Y, Todoroki H, Minami H, Hidaka H. Molecular cloning and sequencing of a cDNA clone encoding a new calcium binding protein, named calgizzarin, from rabbit lung. Biochem Biophys Res Commun. 1991;181:644-9 pubmed
    ..2% homology to S-100 alpha, 38.6% to S-100 beta and 40.0% to annexin II light chain, p10. By Northern blot analysis, with pCALG, a band of 1.1 kbp was detected in rabbit lung, suggesting pCALG contains nearly full length of mRNA. ..
  3. Kioka N, Tsubota J, Kakehi Y, Komano T, Gottesman M, Pastan I, et al. P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance. Biochem Biophys Res Commun. 1989;162:224-31 pubmed
    ..The MDR1 gene, the major member of the P-glycoprotein gene family expressed in human adrenal, is sufficient to confer multidrug-resistance on culture cells. ..
  4. Kushiro M, Shimizu M, Tomita K. Molecular cloning and sequence determination of the tuf gene coding for the elongation factor Tu of Thermus thermophilus HB8. Eur J Biochem. 1987;170:93-8 pubmed
    ..thermophilus HB8 EF-Tu. An extra amino acid sequence of ten residues, consisting predominantly of basic amino acids (Met-182-Gly-191), which does not occur in EF-Tu of E. coli, was found in T. thermophilus HB8. ..
  5. Muramatsu T, Nishikawa K, Nemoto F, Kuchino Y, Nishimura S, Miyazawa T, et al. Codon and amino-acid specificities of a transfer RNA are both converted by a single post-transcriptional modification. Nature. 1988;336:179-81 pubmed
    ..Thus, both the codon and amino-acid specificity of this tRNA are converted by a single post-transcriptional modification of the first position of the anticodon during tRNA maturation. ..
  6. Yabe N, Takahashi T, Komeda Y. Analysis of tissue-specific expression of Arabidopsis thaliana HSP90-family gene HSP81. Plant Cell Physiol. 1994;35:1207-19 pubmed
    ..Only a slight response to IAA was observed in HSP81-1 mRNA accumulation at 22 degrees C; the increase was possibly caused by a novel pathway other than heat-shock-response pathway. ..
  7. Kashiwabuchi N, Ikeda K, Araki K, Hirano T, Shibuki K, Takayama C, et al. Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice. Cell. 1995;81:245-52 pubmed
    ..These results suggest a close relationship between synaptic plasticity and synapse formation in the cerebellum. ..
  8. Sato A, Noda K, Amaya Y, Nishino T. The structure of chicken liver xanthine dehydrogenase. cDNA cloning and the domain structure. J Biol Chem. 1995;270:2818-26 pubmed
    ..The absorption spectrum showed the sample was very similar to deflavo-enzyme. From these results and sequence analyses, the domain structure of the enzyme is discussed. ..
  9. Zu Y, Maekawa T, Nomura N, Nakata T, Ishii S. Regulation of trans-activating capacity of CRE-BPa by phorbol ester tumor promoter TPA. Oncogene. 1993;8:2749-58 pubmed
    ..These results indicate that CRE-BPa is a CRE-dependent trans-activator, and that CRE-BPa can confer TPA inducibility on CRE. Thus, CRE-BPa has an unique characteristic of cross-talk between cAMP pathway and TPA pathway. ..

More Information

Publications341 found, 100 shown here

  1. Saito K, Tatsuguchi K, Murakoshi I, Hirano H. cDNA cloning and expression of cysteine synthase B localized in chloroplasts of Spinacia oleracea. FEBS Lett. 1993;324:247-52 pubmed
    ..coli. RNA blot hybridization suggested that the transcripts were primarily accumulated in leaves of spinach. ..
  2. Yamamoto K, Imae Y. Cloning and characterization of the Salmonella typhimurium-specific chemoreceptor Tcp for taxis to citrate and from phenol. Proc Natl Acad Sci U S A. 1993;90:217-21 pubmed
    ..typhimurium. ..
  3. Goitsuka R, Hayashi N, Nagase M, Sasaki N, Ra C, Tsujimoto H, et al. Molecular cloning of cDNAs encoding dog high-affinity IgE receptor alpha, beta, and gamma chains. Immunogenetics. 1999;49:580-2 pubmed
  4. Tano K, Iwamatsu Y, Yasuhira S, Utsumi H, Takimoto K. Increased base change mutations at G:C pairs in Escherichia coli deficient in endonuclease III and VIII. J Radiat Res. 2001;42:409-13 pubmed
    ..G:C to T:A and to C:G transversions dominated in both mutants. These results suggest that endo III and endo VIII are involved in the repair of oxidative lesions of guanine. ..
  5. Taniya T, Mitobe J, Nakayama S, Mingshan Q, Okuda K, Watanabe H. Determination of the InvE binding site required for expression of IpaB of the Shigella sonnei virulence plasmid: involvement of a ParB boxA-like sequence. J Bacteriol. 2003;185:5158-65 pubmed
    ..These results indicated that InvE bound directly to the promoter region. ..
  6. Matsumoto S, Yamazaki C, Masumoto K, Nagano M, Naito M, Soga T, et al. Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2. Proc Natl Acad Sci U S A. 2006;103:4140-5 pubmed
    ..Our current findings demonstrated that physiological activation of PKR2 is essential for normal development of the OB and sexual maturation...
  7. Hirao T, Watanabe A, Kurita M, Kondo T, Takata K. A frameshift mutation of the chloroplast matK coding region is associated with chlorophyll deficiency in the Cryptomeria japonica virescent mutant Wogon-Sugi. Curr Genet. 2009;55:311-21 pubmed publisher
    ..Therefore, the 19-bp insertion in the matK coding region is the most likely candidate at present for a mutation underlying the Wogon-Sugi phenotype...
  8. Masuo S, Terabayashi Y, Shimizu M, Fujii T, Kitazume T, Takaya N. Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia. Mol Genet Genomics. 2010;284:415-24 pubmed publisher
    ..nidulans controls global transcription to adapt to a hypoxic environment. This study is the first to show that hypoxia elicits systematic transcriptional responses in A. nidulans...
  9. Ogawa T, Okazaki T. Concurrent transcription from the gid and mioC promoters activates replication of an Escherichia coli minichromosome. Mol Gen Genet. 1991;230:193-200 pubmed
    ..These two promoters are suggested to be under stringent control. ..
  10. Noshiro M, Okuda K. Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase. FEBS Lett. 1990;268:137-40 pubmed
    ..The deduced amino acid sequence showed 82% similarity to rat P-450ch7 alpha. Unique amino acid residues were observed in putative binding domains for heme and steroid which are highly conserved in most steroidogenic P-450s. ..
  11. Yanagisawa S. A novel DNA-binding domain that may form a single zinc finger motif. Nucleic Acids Res. 1995;23:3403-10 pubmed
    ..In addition, Southern blot analysis and a survey of DNA databases suggested that proteins that include Dof domains might exist in other eukaryotes, at least in the plant kingdom. ..
  12. Moritani M, Yoshimoto K, Tashiro F, Hashimoto C, Miyazaki J, Ii S, et al. Transgenic expression of IL-10 in pancreatic islet A cells accelerates autoimmune insulitis and diabetes in non-obese diabetic mice. Int Immunol. 1994;6:1927-36 pubmed
  13. Tanaka T, Ida S, Irifune K, Oeda K, Morikawa H. Nucleotide sequence of a gene for nitrite reductase from Arabidopsis thaliana. DNA Seq. 1994;5:57-61 pubmed
    ..This conclusion was confirmed by the analysis using the RT-PCR method. The deduced amino acid sequence of the coding region of the Arabidopsis NiR gene had high similarities with those of NiR genes of other plants including spinach. ..
  14. Yoshida T, Toda T, Yanagida M. A calcineurin-like gene ppb1+ in fission yeast: mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning. J Cell Sci. 1994;107 ( Pt 7):1725-35 pubmed
    ..Thus the ppb1+ gene appears to be involved in cytokinesis, mating, transport, nuclear and spindle pole body positioning, and cell shape. ..
  15. Tanaka K, Takayanagi Y, Fujita N, Ishihama A, Takahashi H. Heterogeneity of the principal sigma factor in Escherichia coli: the rpoS gene product, sigma 38, is a second principal sigma factor of RNA polymerase in stationary-phase Escherichia coli. Proc Natl Acad Sci U S A. 1993;90:3511-5 pubmed
    ..The intracellular level of sigma 38 was demonstrated to increase in vivo upon entry into stationary phase. These results together indicate that sigma 38 is a second principal sigma factor in stationary-phase E. coli. ..
  16. Ueda T, Matsuda N, Anai T, Tsukaya H, Uchimiya H, Nakano A. An Arabidopsis gene isolated by a novel method for detecting genetic interaction in yeast encodes the GDP dissociation inhibitor of Ara4 GTPase. Plant Cell. 1996;8:2079-91 pubmed
    ..AtGDI1 is expressed almost ubiquitously in Arabidopsis tissues. The method described here indicates the physiological interaction of two plant molecules, Ara4 and GDI, in yeast and should be applicable to other foreign genes. ..
  17. Hiroi Y, Komuro I, Chen R, Hosoda T, Mizuno T, Kudoh S, et al. Molecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteins. FEBS Lett. 1998;421:252-8 pubmed
    ..hGAA1 gene is expressed ubiquitously and mRNA levels are higher in the undifferentiated state. Overexpression of antisense hGAA1 in human K562 cells significantly reduced the production of a reporter GPI-anchored protein. ..
  18. Katoh Y, Katoh M. Comparative genomics on FGF7, FGF10, FGF22 orthologs, and identification of fgf25. Int J Mol Med. 2005;16:767-70 pubmed
    ..This is the first report on fgf25 gene and also on the comparative integromics analyses of FGF7, FGF10 and FGF22 orthologs. ..
  19. Matsushita M, Tada S, Suzuki S, Kusumoto K, Kashiwagi Y. Deletion analysis of the promoter of Aspergillus oryzae gene encoding heat shock protein 30. J Biosci Bioeng. 2009;107:345-51 pubmed publisher
    ..Furthermore, site-directed mutagenesis of this promoter revealed that HSE1 (aTTCgtcGAAacgcccaGAAa) and HSE2 (cGAAagTTCtcGACg), located between -342 and -272 of the hsp30 promoter, were its cis-acting elements for heat shock response...
  20. Kobayashi T, Koide O, Deguchi S, Horikoshi K. Characterization of chitosanase of a deep biosphere Bacillus strain. Biosci Biotechnol Biochem. 2011;75:669-73 pubmed
    ..Although Cho-GG did not show the definite characteristics of a sub-seafloor ectoenzyme, the thermal stability of many chitosanases of B. turingienesis and other related strains can be improved by adding chitotriose or chitotetraose. ..
  21. Tani S, Kanamasa S, Sumitani J, Arai M, Kawaguchi T. XlnR-independent signaling pathway regulates both cellulase and xylanase genes in response to cellobiose in Aspergillus aculeatus. Curr Genet. 2012;58:93-104 pubmed publisher
    ..aculeatus perceives the presence of cellobiose, thereby activating a signaling pathway that drives cellulase and hemicellulase gene expression under the control of the XlnR-independent regulation through CeRE. ..
  22. Oda Y, Nakanishi I, Deguchi T. A complementary DNA for human choline acetyltransferase induces two forms of enzyme with different molecular weights in cultured cells. Brain Res Mol Brain Res. 1992;16:287-94 pubmed
    ..It might be that the larger form of ChAT molecule is an enzyme precursor for processing or that the N-terminal extrapeptide is needed for subcellular localization of the enzyme. ..
  23. Tanaka H, Hoshi J, Nakata K, Chung I, Ito T, Ohta A, et al. Partial sequence of acid phosphatase-1(1) gene (Aps-1(1)) linked to nematode resistance gene (Mi) of tomato. Biosci Biotechnol Biochem. 1992;56:583-7 pubmed
    ..As a result, a single band with a size that could be cloned into a YAC vector was detected when the genomic DNA was digested with some kinds of restriction enzymes. ..
  24. Nagao T, Mitamura T, Wang X, Negoro S, Yomo T, Urabe I, et al. Cloning, nucleotide sequences, and enzymatic properties of glucose dehydrogenase isozymes from Bacillus megaterium IAM1030. J Bacteriol. 1992;174:5013-20 pubmed
    ..The phylogenic relationship of these glucose dehydrogenase genes is also discussed. ..
  25. Yoshida K, Oshima A, Shimmoto M, Fukuhara Y, Sakuraba H, Yanagisawa N, et al. Human beta-galactosidase gene mutations in GM1-gangliosidosis: a common mutation among Japanese adult/chronic cases. Am J Hum Genet. 1991;49:435-42 pubmed
    ..Genotype-phenotype correlations in GM1-gangliosidosis are briefly discussed...
  26. Amaya Y, Yamazaki K, Sato M, Noda K, Nishino T. Proteolytic conversion of xanthine dehydrogenase from the NAD-dependent type to the O2-dependent type. Amino acid sequence of rat liver xanthine dehydrogenase and identification of the cleavage sites of the enzyme protein during irreversible conversi. J Biol Chem. 1990;265:14170-5 pubmed
    ..Hydropathy analysis around the cysteine residues suggests that the 2Fe/2S sites are associated with the 20-kDa fragment portion of the enzyme. ..
  27. Nojima H. Structural organization of multiple rat calmodulin genes. J Mol Biol. 1989;208:269-82 pubmed
    ..Together with these, I report here the structures of the third and fourth calmodulin retropseudogenes. ..
  28. Kondo T, Uenishi H, Shimizu T, Hirama T, Iwashiro M, Kuribayashi K, et al. A single retroviral gag precursor signal peptide recognized by FBL-3 tumor-specific cytotoxic T lymphocytes. J Virol. 1995;69:6735-41 pubmed
    ..These novel observations suggest that expression of Pr75gag in FBL-3 tumor cells led to the amplification of CTLs which recognize the signal sequence of the nonstructural gag-encoded glycoprotein precursor. ..
  29. Yasue H, Kusumoto H, Mikami H. Assignment of the uteroferrin gene (ACP5) to swine chromosome 2q12-->q21 by fluorescence in situ hybridization. Cytogenet Cell Genet. 1995;71:249-52 pubmed
    ..The hybridization signals revealed that the uteroferrin gene (ACP5) is located on swine chromosome 2q12-->q21. ..
  30. Higashitsuji H, Arii S, Furutani M, Imamura M, Kaneko Y, Takenawa J, et al. Enhanced expression of multiple protein tyrosine phosphatases in the regenerating mouse liver: isolation of PTP-RL10, a novel cytoplasmic-type phosphatase with sequence homology to cytoskeletal protein 4.1. Oncogene. 1995;10:407-14 pubmed
    ..The differential expression of multiple PTPs during the pre-replicative and post-replicative stages of liver regeneration suggests that PTPs are involved in the regulation of growth and differentiation of liver cells. ..
  31. Ohta H, Tsurudome M, Matsumura H, Koga Y, Morikawa S, Kawano M, et al. Molecular and biological characterization of fusion regulatory proteins (FRPs): anti-FRP mAbs induced HIV-mediated cell fusion via an integrin system. EMBO J. 1994;13:2044-55 pubmed
    ..FRP-mediated fusion was temperature, cytoskeleton, energy and Ca2+ dependent. These experiments showed a possible regulatory function of cell fusion by an integrin system(s). ..
  32. Tanimura A, Teshima H, Fujisawa J, Yoshida M. A new regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1 and cloning of cDNAs encoding its binding proteins. J Virol. 1993;67:5375-82 pubmed
    ..These results suggest that binding of THP to TRE-2S may be involved in cooperation with one copy of the 21-bp enhancer in responding to Tax trans activation. ..
  33. Kageyama T. Rabbit procathepsin E and cathepsin E. Nucleotide sequence of cDNA, hydrolytic specificity for biologically active peptides and gene expression during development. Eur J Biochem. 1993;216:717-28 pubmed
    ..The enzyme may also regulate the physiological activities of adult tissues which are mediated by substance P and related tachykinins. ..
  34. Nikata T, Sakai Y, Shibat K, Kato J, Kuroda A, Ohtake H. Molecular analysis of the phosphate-specific transport (pst) operon of Pseudomonas aeruginosa. Mol Gen Genet. 1996;250:692-8 pubmed
    ..The phoU and pstB genes are essential for repressing P(i) taxis. However, mutants lacking either PstC or PstA alone were able to repress P(i) taxis under conditions of P(i) excess...
  35. Isomura M, Okui K, Fujiwara T, Shin S, Nakamura Y. Cloning and mapping of a novel human cDNA homologous to DROER, the enhancer of the Drosophila melanogaster rudimentary gene. Genomics. 1996;32:125-7 pubmed
    ..The ERH gene was expressed in all normal human tissues examined. We assigned the ERH gene locus to chromosomal band 7q34 by fluorescence in situ hybridization. ..
  36. Iwama A, Yamaguchi N, Suda T. STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family. EMBO J. 1996;15:5866-75 pubmed
    ..Our findings provide the first evidence for apoptosis via a receptor tyrosine kinase. ..
  37. Kondo K, Horinouchi S. Characterization of an insertion sequence, IS12528, from Gluconobacter suboxydans. Appl Environ Microbiol. 1997;63:1139-42 pubmed
    ..These observations suggest that IS12528 is one of the insertion sequences that are responsible for genetic instability leading to deficiencies in various physiological properties in a variety of acetic acid bacteria. ..
  38. Ihara K, Watanabe S, Sugimura K, Katagiri I, Mukohata Y. Identification of proteolipid from an extremely halophilic archaeon Halobacterium salinarum as an N,N'-dicyclohexyl-carbodiimide binding subunit of ATP synthase. Arch Biochem Biophys. 1997;341:267-72 pubmed
    ..J. Bult et al. (1996) Science 273, 1058-1073], proteolipids from archaea seem to have diverse characteristics in comparison with those from eubacteria or from eukaryotes. ..
  39. Himeno H, Sato M, Tadaki T, Fukushima M, Ushida C, Muto A. In vitro trans translation mediated by alanine-charged 10Sa RNA. J Mol Biol. 1997;268:803-8 pubmed
    ..The dual function of 10Sa RNA both as an mRNA and as a tRNA in vitro strongly supports the trans translation hypothesis. ..
  40. Ohashi K, Natori S, Kubo T. Change in the mode of gene expression of the hypopharyngeal gland cells with an age-dependent role change of the worker honeybee Apis mellifera L. Eur J Biochem. 1997;249:797-802 pubmed
    ..Therefore, the individual secretory cells of the acinus of the hypopharyngeal gland were shown to express these genes differently with the age-dependent role change of the worker bee...
  41. Masumoto N, Ikebuchi Y, Tahara M, Yokoi T, Tasaka K, Miyake A, et al. Expression of Rab3A in the cortical region in mouse metaphase II eggs. J Exp Zool. 1998;280:91-6 pubmed
    ..However, it was not detected at the three- or four-cell stage 40 hr after fertilization. These results suggest that Rab3A may function with Rabphilin-3A in CG exocytosis. ..
  42. Fukuoka S, Nyaruhucha C, Shibata K. Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase. Biochim Biophys Acta. 1998;1395:192-201 pubmed
    ..It is concluded that the cloned cDNA encodes human QPRTase which is functional beyond the phylogenic boundary. ..
  43. Hidaka S, Kakuma T, Yoshimatsu H, Yasunaga S, Kurokawa M, Sakata T. Molecular cloning of rat uncoupling protein 2 cDNA and its expression in genetically obese Zucker fatty (fa/fa) rats. Biochim Biophys Acta. 1998;1389:178-86 pubmed
  44. Matsushita M, Yamadori T, Kato S, Takemoto Y, Inazawa J, Baba Y, et al. Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (BtK). Biochem Biophys Res Commun. 1998;245:337-43 pubmed
    ..Remarkably, Sab exhibited a high preference for binding to Btk rather than to other cytoplasmic tyrosine kinases, which suggests a unique role of Sab in the Btk signal transduction pathway. ..
  45. Shimoi H, Kitagaki H, Ohmori H, Iimura Y, Ito K. Sed1p is a major cell wall protein of Saccharomyces cerevisiae in the stationary phase and is involved in lytic enzyme resistance. J Bacteriol. 1998;180:3381-7 pubmed
    ..These results indicate that Sed1p is a major structural cell wall protein in stationary-phase cells and is required for lytic enzyme resistance. ..
  46. Mino K, Yamanoue T, Sakiyama T, Eisaki N, Matsuyama A, Nakanishi K. Purification and characterization of serine acetyltransferase from Escherichia coli partially truncated at the C-terminal region. Biosci Biotechnol Biochem. 1999;63:168-79 pubmed
    ..However, SAT delta C20 did not form a complex with O-acetylserine sulfhydrylase-A (OASS-A), a counterpart of the cysteine synthetase and did not reduce OASS activity in contrast to the wild-type SAT and Met-256-Ile mutant SAT. ..
  47. Yamauchi T, Toko M, Suga M, Hatakeyama T, Isobe M. Structural organization of the human Elk1 gene and its processed pseudogene Elk2. DNA Res. 1999;6:21-7 pubmed
    ..2 --> qter region in addition to Elk2 locus between IGHA1 and IGHGP loci. ..
  48. Kusaba S, Honda C, Kano Murakami Y. Isolation and expression analysis of gibberellin 20-oxidase homologous gene in apple. J Exp Bot. 2001;52:375-6 pubmed
    ..The transcript of this gene was detected mainly in immature seeds between 1-3 months after full bloom. These results suggested that this apple GA 20-oxidase gene might be involved in GA biosynthesis in developing apple seed. ..
  49. Matsuo E, Mori H, Ito K. Interfering mutations provide in vivo evidence that Escherichia coli SecE functions in multimeric states. Mol Genet Genomics. 2003;268:808-15 pubmed
    ..The data hence suggest that dimeric SecE participates in the formation of the functional translocation channel. ..
  50. Abe H, Ohba M, Shimma Y, Jigami Y. Yeast cells harboring human alpha-1,3-fucosyltransferase at the cell surface engineered using Pir, a cell wall-anchored protein. FEMS Yeast Res. 2004;4:417-25 pubmed
  51. Sato H, Nomura S, Maebara K, Sato K, Tamba M, Bannai S. Transcriptional control of cystine/glutamate transporter gene by amino acid deprivation. Biochem Biophys Res Commun. 2004;325:109-16 pubmed
    ..These results demonstrate that xCT is a new member of the proteins whose transcriptional control by the amino acid deprivation is mediated by AARE. ..
  52. Katoh M, Katoh M. Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. Int J Oncol. 2007;30:1273-7 pubmed
  53. Katoh M, Katoh M. Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. Int J Oncol. 2007;31:461-6 pubmed
    ..Together these facts indicate that HES1 and HES3 were target genes of the ES cell-specific network of transcription factors, and that HES1, HES5, HEY1, HEY2 and HEYL were target genes of Notch signaling pathway. ..
  54. Fukamizu A, Takahashi S, Seo M, Tada M, Tanimoto K, Uehara S, et al. Structure and expression of the human angiotensinogen gene. Identification of a unique and highly active promoter. J Biol Chem. 1990;265:7576-82 pubmed
    ..Since the basal expression of the human angiotensinogen gene is much higher in HepG2 than T98G cells, these results may reflect cell-specific differences in the gene transcription. ..
  55. Ohyama Y, Noshiro M, Okuda K. Cloning and expression of cDNA encoding 25-hydroxyvitamin D3 24-hydroxylase. FEBS Lett. 1991;278:195-8 pubmed
    ..Using the cDNA as a probe we demonstrated that the increase of 24-hydroxylation activity caused by administration of vitamin D3 into rats was accompanied by an increase of the mRNA. ..
  56. Sato T, Theeragool G, Yamamoto T, Okamoto M, Kobayashi Y. Revised nucleotide sequence of the sporulation gene spoVE from Bacillus subtilis. Nucleic Acids Res. 1990;18:4021 pubmed
  57. Kaupp U, Niidome T, Tanabe T, Terada S, Bönigk W, Stuhmer W, et al. Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature. 1989;342:762-6 pubmed
    ..Expression of the complementary DNA produces cyclic GMP-gated channel activity in Xenopus oocytes. ..
  58. Konishi H, Kuroda S, Tanaka M, Matsuzaki H, Ono Y, Kameyama K, et al. Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins. Biochem Biophys Res Commun. 1995;216:526-34 pubmed
    ..These results suggest that the pleckstrin homology domains of RAC protein kinase family could associate more than one protein to regulate the activity and/or intracellular distribution of this enzyme family by different ways. ..
  59. Tanaka T, Furukawa F, Imamura S. Epitope mapping for epidermolysis bullosa acquisita autoantibody by molecularly cloned cDNA for type VII collagen. J Invest Dermatol. 1994;102:706-9 pubmed
    ..These data suggest that multiple epitopes on the N-terminal non-collagenous domain of type VII collagen are recognized by circulating autoantibodies in patients with epidermolysis bullosa acquisita. ..
  60. Kai M, Eto T, Kondo K, Setoguchi Y, Higashi S, Maeda Y, et al. Synchronous circadian rhythms of mRNA levels and activities of cholesterol 7 alpha-hydroxylase in the rabbit and rat. J Lipid Res. 1995;36:367-74 pubmed
    ..Because the rhythms of mRNA levels and activities of this enzyme are synchronous, the turnover of the enzyme should be as fast as that of the mRNA, and we can hereafter measure the mRNA levels instead of the enzyme. ..
  61. Shirayama M, Matsui Y, Tanaka K, Toh e A. Isolation of a CDC25 family gene, MSI2/LTE1, as a multicopy suppressor of ira1. Yeast. 1994;10:451-61 pubmed
    ..These results suggest that MSI2 is involved in the termination of M phase and that this process is regulated by a ras superfamily gene product. ..
  62. Nishio H, Takeshima Y, Narita N, Yanagawa H, Suzuki Y, Ishikawa Y, et al. Identification of a novel first exon in the human dystrophin gene and of a new promoter located more than 500 kb upstream of the nearest known promoter. J Clin Invest. 1994;94:1037-42 pubmed
    ..The sequence of part of the new promoter region is very similar to that of certain medium reiteration frequency repetitive sequences. These findings may help us understand the molecular evolution of the dystrophin gene. ..
  63. Iida Y, Takeda J, Miyata T, Inoue N, Nishimura J, Kitani T, et al. Characterization of genomic PIG-A gene: a gene for glycosylphosphatidylinositol-anchor biosynthesis and paroxysmal nocturnal hemoglobinuria. Blood. 1994;83:3126-31 pubmed
    ..We report pairs of oligonucleotide primers for polymerase chain reaction that should be useful to amplify and analyze various regions of the PIG-A gene in patients with PNH. ..
  64. Ito Y, Kobayashi T, Kimura T, Matsuura N, Wakasugi E, Takeda T, et al. Investigation of the oxytocin receptor expression in human breast cancer tissue using newly established monoclonal antibodies. Endocrinology. 1996;137:773-9 pubmed
    ..These findings indicated that the OTR is expressed in breast cancer derived not from the myoepithelium but from the glandular or ductal epithelium; however, the biological function of OT in breast cancer remains to be determined. ..
  65. Hiratsu K, Shinagawa H, Makino K. Mode of promoter recognition by the Escherichia coli RNA polymerase holoenzyme containing the sigma S subunit: identification of the recognition sequence of the fic promoter. Mol Microbiol. 1995;18:841-50 pubmed
  66. Akao Y, Matsuda Y. Identification and chromosome mapping of the mouse homologue of the human gene (DDX6) that encodes a putative RNA helicase of the DEAD box protein family. Cytogenet Cell Genet. 1996;75:38-44 pubmed
    ..A 7.5-kb mRNA and a 54-kDa protein were identified as mouse Ddx6 gene products which are similar in size to products of the human DDX6 gene, as shown by Northern and Western blot analyses. ..
  67. Saito K, Takagi Y, Ling H, Takahashi H, Noji M. Molecular cloning, characterization and expression of cDNA encoding phosphoserine aminotransferase involved in phosphorylated pathway of serine biosynthesis from spinach. Plant Mol Biol. 1997;33:359-66 pubmed
    ..RNA blot hybridization suggested the preferential expression of the Psa gene in the roots of green seedlings and in the suspension cells cultured under a dark condition...
  68. Okanami M, Meshi T, Tamai H, Iwabuchi M. HALF-1, a bZIP-type protein, interacting with the wheat transcription factor HBP-1a contains a novel transcriptional activation domain. Genes Cells. 1996;1:87-99 pubmed
    ..We identified a novel trans-activation domain which contains the GCB motif conserved among plant bZIP-type factors. The trans-activation appears to be mediated by interaction between the GCB motif and a factor conserved in plants. ..
  69. Hibino Y, Tsukada S, Sugano N. Purification and characterization of a DNA binding protein in a nuclear scaffold fraction from rat ascites hepatoma cells. Carcinogenesis. 1997;18:707-13 pubmed
  70. Yamazaki N, Yamanaka Y, Hashimoto Y, Shinohara Y, Shima A, Terada H. Structural features of the gene encoding human muscle type carnitine palmitoyltransferase I. FEBS Lett. 1997;409:401-6 pubmed
    ..Comparison of the gene structure of human CPTI-M with the reported partial gene structure of human liver type CPTI (CPTI-L) showed that the intron insertion sites were completely conserved in these two genes. ..
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