Experts and Doctors on immunoenzyme techniques in Chengdu, Sichuan, China


Locale: Chengdu, Sichuan, China
Topic: immunoenzyme techniques

Top Publications

  1. Liu J, Weiss H, Rychahou P, Jackson L, Evers B, Gao T. Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis. Oncogene. 2009;28:994-1004 pubmed publisher
    ..Moreover, reexpression of either PHLPP isoform in HCT116 cells inhibited tumor growth in vivo. Taken together, our results strongly support a tumor suppressor role of PHLPP in colon cancer. ..
  2. Chen L, Ma C, He J, He Y, Wang J, Gou L, et al. Preparation of anti-hECSM2 mouse monoclonal antibodies and their application in the analysis of hECSM2 expression. Monoclon Antib Immunodiagn Immunother. 2013;32:301-8 pubmed publisher
    ..Our anti-hECSM2 mouse antibodies can be used for Western blot, flow cytometry, and immunohistochemistry study, and can be a valuable tool for investigating the function and distribution of hECSM2. ..
  3. Wei B, Wang J, Bourne P, Yang Q, Hicks D, Bu H, et al. Bone metastasis is strongly associated with estrogen receptor-positive/progesterone receptor-negative breast carcinomas. Hum Pathol. 2008;39:1809-15 pubmed publisher
  4. Liu Q, Zhao X, Bai R, Liang S, Nie C, Yuan Z, et al. Induction of tumor inhibition and apoptosis by a candidate tumor suppressor gene DRR1 on 3p21.1. Oncol Rep. 2009;22:1069-75 pubmed
    ..DRR1 is a potent growth suppressor of NSCLC, acting through apoptosis pathway in vivo and it may be a potential therapeutic gene for human lung cancer. ..
  5. Zhang Z, Pan J, Li L, Wang Z, Xiao W, Li N. Survey of risk factors contributed to lymphatic metastasis in patients with oral tongue cancer by immunohistochemistry. J Oral Pathol Med. 2011;40:127-34 pubmed publisher
    ..Here, we investigated the expression levels of seven biomarkers in oral squamous cell carcinoma (OSCC) tissues as well as their associations with the clinicopathologic features of OTSCC patients...
  6. Xu W, Chen J, Chen H, Diao R, Fok K, Dong J, et al. Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia. PLoS ONE. 2011;6:e19120 pubmed publisher
    ..Altered CFTR-sAC-cAMP-CREB functional loop may also underline the pathogenesis of various CF-related diseases. ..
  7. Liu L, Ge D, Ma L, Mei J, Liu S, Zhang Q, et al. Interleukin-17 and prostaglandin E2 are involved in formation of an M2 macrophage-dominant microenvironment in lung cancer. J Thorac Oncol. 2012;7:1091-100 pubmed publisher
    ..IL-17 recruits macrophages, and PGE2 induces M2-macrophage differentiation, hence the increased levels of IL-17 and PGE2 in lung cancer contribute to the formation of an M2-macrophage-dominant tumor microenvironment. ..
  8. Wu Z, Peng X, Li J, Zhang Y, Hu L. Constitutive activation of nuclear factor ?B contributes to cystic fibrosis transmembrane conductance regulator expression and promotes human cervical cancer progression and poor prognosis. Int J Gynecol Cancer. 2013;23:906-15 pubmed publisher
    ..Multivariate analysis revealed that coexpression of CFTR and NF-?B was associated with poor prognosis in patients with cervical cancer. ..
  9. Zhang Y, Ni H, Cheng D. Prognostic value of phosphorylated mTOR/RPS6KB1 in non- small cell lung cancer. Asian Pac J Cancer Prev. 2013;14:3725-8 pubmed
    ..01). Multivariate analysis indicated high level of p-mTOR expression was an independent prognostic factor (HR=2.642, 95%CI 1.157-4.904, p=0.002). p-mTOR and p-RPS6KB1 could be useful prognostic markers for NSCLC. ..

More Information


  1. He Y, Huang J, Wang P, Shen X, Li S, Yang L, et al. Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome. Oncotarget. 2016;7:4664-79 pubmed publisher
    ..Therefore, emodin warrants further investigation as a new means to enhance the efficacy of IFN-α/β. ..