Gene Symbol: Tb10.6k15.2620
Description: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Alias: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Species: Trypanosoma brucei TREU927
- Hutchings N, Donelson J, Hill K. Trypanin is a cytoskeletal linker protein and is required for cell motility in African trypanosomes. J Cell Biol. 2002;156:867-77 pubmed publisher..These results indicate that trypanin functions as a cytoskeletal linker protein and offer insights into the mechanisms of flagellum-based cell motility...
- Chevalier N, Rigden D, Van Roy J, Opperdoes F, Michels P. Trypanosoma brucei contains a 2,3-bisphosphoglycerate independent phosphoglycerate mutase. Eur J Biochem. 2000;267:1464-72 pubmed..The presence of distinct nonhomologous PGAMs in the parasite and its human host offers great potential for the design of selective inhibitors which could form leads for new trypanocidal drugs...