SLC25A37

Summary

Gene Symbol: SLC25A37
Description: solute carrier family 25 member 37
Alias: HT015, MFRN, MFRN1, MSC, MSCP, PRO1278, PRO1584, PRO2217, mitoferrin-1, mitochondrial iron transporter 1, mitochondrial solute carrier protein, mitoferrin, solute carrier family 25 (mitochondrial iron transporter), member 37
Species: human
Products:     SLC25A37

Top Publications

  1. Hu G, Mai T, Chen C. Visualizing the GPCR Network: Classification and Evolution. Sci Rep. 2017;7:15495 pubmed publisher
    In this study, we delineate an unsupervised clustering algorithm, minimum span clustering (MSC), and apply it to detect G-protein coupled receptor (GPCR) sequences and to study the GPCR network using a base dataset of 2770 GPCR and 652 ..
  2. Liang Y, Wang X, Deng L, Wang L, Wang Y, Huang Y, et al. [Biological characteristics of Microvesicles Derived from Bone Marrow Mesenchymal Stem Cells and Their Capacities Supporting ex vivo Expansion of Hematopoietic Stem Cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017;25:1187-1193 pubmed publisher
    To explore the biological characteristics of microvesicles(MV) derived from bone marrow mesenchymal stem cells (BM-MSC) and their capability supporting ex vivo expansion of hematopoietic stem cells(HSC)...
  3. Zhang Y, Xu C, Gu D, Wu M, Yan B, Xu Z, et al. H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells. Stem Cells. 2017;35:222-235 pubmed publisher
    ..Taken together, our study for the first time showed that H/ACA box snoRNAs are actively involved in MSC proliferation as well as pluripotency control, and we identify SNORA7A as one of the critical snoRNAs that regulate ..
  4. Moya A, Larochette N, Paquet J, Deschepper M, Bensidhoum M, Izzo V, et al. Quiescence Preconditioned Human Multipotent Stromal Cells Adopt a Metabolic Profile Favorable for Enhanced Survival under Ischemia. Stem Cells. 2017;35:181-196 pubmed publisher
    A major impediment to the development of therapies with mesenchymal stem cells/multipotent stromal cells (MSC) is the poor survival and engraftment of MSCs at the site of injury...
  5. Xin H, Wang F, Li Y, Lu Q, Cheung W, Zhang Y, et al. Secondary Release of Exosomes From Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery After Stroke in Rats Treated With Exosomes Harvested From MicroRNA 133b-Overexpressing Multipotent Mesenchymal Strom. Cell Transplant. 2017;26:243-257 pubmed publisher
    ..MCAO) compared with naive MSCs and that exosomes generated from naive MSCs mediate the therapeutic benefits of MSC therapy for stroke...
  6. Lee H, Jo E, Kim S, Yang H, Kim Y, Sung Y, et al. Therapeutic strategies for locally recurrent and metastatic de-differentiated liposarcoma with herpes simplex virus-thymidine kinase-expressing mesenchymal stromal cells. Cytotherapy. 2017;19:1035-1047 pubmed publisher
    ..a new approach to DDLPS therapy with mesenchymal stromal cells expressing herpes simplex virus-thymidine kinase (MSC-TK)...
  7. Wang L, Li P, Tian Y, Li Z, Lian C, Ou Q, et al. Human umbilical cord mesenchymal stem cells: subpopulations and their difference in cell biology and effects on retinal degeneration in RCS rats. Curr Mol Med. 2017;: pubmed publisher
    ..To further study the biology and therapeutic effects of these cells, two hUC-MSC subpopulations, termed hUC-MSC1 and hUC-MSC2, were isolated by single-cell cloning method and their therapeutic ..
  8. Augustine S, Avey M, Harrison B, Locke T, Ghannad M, Moher D, et al. Mesenchymal Stromal Cell Therapy in Bronchopulmonary Dysplasia: Systematic Review and Meta-Analysis of Preclinical Studies. Stem Cells Transl Med. 2017;: pubmed publisher
    ..1990 to present) for controlled comparative studies of neonatal animal models that received MSCs or cell free MSC-derived conditioned media (MSC-CM). Lung alveolarization was the primary outcome...
  9. Kasoju N, Wang H, Zhang B, George J, Gao S, Triffitt J, et al. Transcriptomics of human multipotent mesenchymal stromal cells: Retrospective analysis and future prospects. Biotechnol Adv. 2017;35:407-418 pubmed publisher
    ..In this article, we address the challenges associated with MSC transcriptome studies, the paradoxes observed in published experimental results and the need for careful ..
  10. Lohan P, Treacy O, Griffin M, Ritter T, Ryan A. Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?. Front Immunol. 2017;8:1626 pubmed publisher
    Mesenchymal stromal cells (MSC) have been used to treat a broad range of disease indications such as acute and chronic inflammatory disorders, autoimmune diseases, and transplant rejection due to their potent immunosuppressive/anti-..

Detail Information

Publications62

  1. Hu G, Mai T, Chen C. Visualizing the GPCR Network: Classification and Evolution. Sci Rep. 2017;7:15495 pubmed publisher
    In this study, we delineate an unsupervised clustering algorithm, minimum span clustering (MSC), and apply it to detect G-protein coupled receptor (GPCR) sequences and to study the GPCR network using a base dataset of 2770 GPCR and 652 ..
  2. Liang Y, Wang X, Deng L, Wang L, Wang Y, Huang Y, et al. [Biological characteristics of Microvesicles Derived from Bone Marrow Mesenchymal Stem Cells and Their Capacities Supporting ex vivo Expansion of Hematopoietic Stem Cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017;25:1187-1193 pubmed publisher
    To explore the biological characteristics of microvesicles(MV) derived from bone marrow mesenchymal stem cells (BM-MSC) and their capability supporting ex vivo expansion of hematopoietic stem cells(HSC)...
  3. Zhang Y, Xu C, Gu D, Wu M, Yan B, Xu Z, et al. H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells. Stem Cells. 2017;35:222-235 pubmed publisher
    ..Taken together, our study for the first time showed that H/ACA box snoRNAs are actively involved in MSC proliferation as well as pluripotency control, and we identify SNORA7A as one of the critical snoRNAs that regulate ..
  4. Moya A, Larochette N, Paquet J, Deschepper M, Bensidhoum M, Izzo V, et al. Quiescence Preconditioned Human Multipotent Stromal Cells Adopt a Metabolic Profile Favorable for Enhanced Survival under Ischemia. Stem Cells. 2017;35:181-196 pubmed publisher
    A major impediment to the development of therapies with mesenchymal stem cells/multipotent stromal cells (MSC) is the poor survival and engraftment of MSCs at the site of injury...
  5. Xin H, Wang F, Li Y, Lu Q, Cheung W, Zhang Y, et al. Secondary Release of Exosomes From Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery After Stroke in Rats Treated With Exosomes Harvested From MicroRNA 133b-Overexpressing Multipotent Mesenchymal Strom. Cell Transplant. 2017;26:243-257 pubmed publisher
    ..MCAO) compared with naive MSCs and that exosomes generated from naive MSCs mediate the therapeutic benefits of MSC therapy for stroke...
  6. Lee H, Jo E, Kim S, Yang H, Kim Y, Sung Y, et al. Therapeutic strategies for locally recurrent and metastatic de-differentiated liposarcoma with herpes simplex virus-thymidine kinase-expressing mesenchymal stromal cells. Cytotherapy. 2017;19:1035-1047 pubmed publisher
    ..a new approach to DDLPS therapy with mesenchymal stromal cells expressing herpes simplex virus-thymidine kinase (MSC-TK)...
  7. Wang L, Li P, Tian Y, Li Z, Lian C, Ou Q, et al. Human umbilical cord mesenchymal stem cells: subpopulations and their difference in cell biology and effects on retinal degeneration in RCS rats. Curr Mol Med. 2017;: pubmed publisher
    ..To further study the biology and therapeutic effects of these cells, two hUC-MSC subpopulations, termed hUC-MSC1 and hUC-MSC2, were isolated by single-cell cloning method and their therapeutic ..
  8. Augustine S, Avey M, Harrison B, Locke T, Ghannad M, Moher D, et al. Mesenchymal Stromal Cell Therapy in Bronchopulmonary Dysplasia: Systematic Review and Meta-Analysis of Preclinical Studies. Stem Cells Transl Med. 2017;: pubmed publisher
    ..1990 to present) for controlled comparative studies of neonatal animal models that received MSCs or cell free MSC-derived conditioned media (MSC-CM). Lung alveolarization was the primary outcome...
  9. Kasoju N, Wang H, Zhang B, George J, Gao S, Triffitt J, et al. Transcriptomics of human multipotent mesenchymal stromal cells: Retrospective analysis and future prospects. Biotechnol Adv. 2017;35:407-418 pubmed publisher
    ..In this article, we address the challenges associated with MSC transcriptome studies, the paradoxes observed in published experimental results and the need for careful ..
  10. Lohan P, Treacy O, Griffin M, Ritter T, Ryan A. Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?. Front Immunol. 2017;8:1626 pubmed publisher
    Mesenchymal stromal cells (MSC) have been used to treat a broad range of disease indications such as acute and chronic inflammatory disorders, autoimmune diseases, and transplant rejection due to their potent immunosuppressive/anti-..
  11. Huang D, Yin L, Liu X, Lv B, Xie Z, Wang X, et al. Geraniin protects bone marrow‑derived mesenchymal stem cells against hydrogen peroxide‑induced cellular oxidative stress in vitro. Int J Mol Med. 2017;: pubmed publisher
    ..Therefore, strategies that attenuate oxidative stress‑induced damage and enhance MSC viability are required...
  12. Ko J, Lee H, Jeong H, Oh J. Ly6Chi monocytes are required for mesenchymal stem/stromal cell-induced immune tolerance in mice with experimental autoimmune uveitis. Biochem Biophys Res Commun. 2017;494:6-12 pubmed publisher
    ..macrophages is increased in the lung by intravenous (IV) administration of mesenchymal stem/stromal cells (MSC) and induces immune tolerance...
  13. Kang R, Li H, Lysdahl H, Quang Svend Le D, Chen M, Xie L, et al. Cyanoacrylate medical glue application in intervertebral disc annulus defect repair: Mechanical and biocompatible evaluation. J Biomed Mater Res B Appl Biomater. 2017;105:14-20 pubmed publisher
    ..Furthermore, the in vitro response of mesenchymal stem cell (MSC) to the glue was evaluated by cell viability assay...
  14. Guo H, Zhao N, Gao H, He X. Mesenchymal Stem Cells Overexpressing Interleukin-35 Propagate Immunosuppressive Effects in Mice. Scand J Immunol. 2017;86:389-395 pubmed publisher
    ..Mouse Ad-MSCs were isolated and cultured. IL-35 was expressed in the MSC supernatant and serum after IL-35 transduction into Ad-MSCs by lentiviral vector transfection in vitro and in vivo...
  15. Hasegawa S, Fujiwara T, Okitsu Y, Kato H, Sato Y, Fukuhara N, et al. Effects of in vivo deletion of GATA2 in bone marrow stromal cells. Exp Hematol. 2017;56:31-45.e2 pubmed publisher
    ..We did not find any phenotypic changes when Gata2 was deleted with BM-MSC-related gene promoters, such as Nestin, Prx1, and Lepr, except for a significant decrease in the colony number of ..
  16. Woldendorp K, Boonstra A, Arendzen J, Reneman M. Variation in occupational exposure associated with musculoskeletal complaints: a cross-sectional study among professional bassists. Int Arch Occup Environ Health. 2017;: pubmed publisher
    ..occupational exposure is assumed to have a protective effect against the development of musculoskeletal complaints (MSC), but this common assumption is not strongly supported by the literature...
  17. Bwalya E, Kim S, Fang J, Wijekoon H, Hosoya K, Okumura M. Effects of pentosan polysulfate and polysulfated glycosaminoglycan on chondrogenesis of canine bone marrow-derived mesenchymal stem cells in alginate and micromass culture. J Vet Med Sci. 2017;79:1182-1190 pubmed publisher
    Mesenchymal stem cells (MSC) are a potential alternative source of differentiated chondrocytes for cartilage tissue regeneration and repair of osteoarthritic (OA) joints...
  18. Schoefinius J, Brunswig Spickenheier B, Speiseder T, Krebs S, Just U, Lange C. Mesenchymal Stromal Cell-Derived Extracellular Vesicles Provide Long-Term Survival After Total Body Irradiation Without Additional Hematopoietic Stem Cell Support. Stem Cells. 2017;: pubmed publisher
    The therapeutic effect of mesenchymal stromal cells (MSC) in tissue regeneration is based mainly on the secretion of bioactive molecules...
  19. Zavan B, Ferroni L, Gardin C, Sivolella S, Piattelli A, Mijiritsky E. Release of VEGF from Dental Implant Improves Osteogenetic Process: Preliminary In Vitro Tests. Materials (Basel). 2017;10: pubmed publisher
    ..The ability of VEGF-enriched titanium implants to improve the osteogenetic properties of Mesenchymal stem cells (MSC), also in the presence of an inflammatory environment, have been in vitro tested...
  20. Hervé M, Ibrahim E. MicroRNA screening identifies a link between NOVA1 expression and a low level of IKAP in familial dysautonomia. Dis Model Mech. 2016;9:899-909 pubmed publisher
    ..and reverse transcription coupled to quantitative PCR (RT-qPCR) on two biological replicate series of hOE-MSC cultures from healthy controls and FD patients...
  21. Jiang Z, Liu G, Meng F, Wang W, Hao P, Xiang Y, et al. Paracrine effects of mesenchymal stem cells on the activation of keratocytes. Br J Ophthalmol. 2017;101:1583-1590 pubmed publisher
    The purpose of this study is to investigate the impact of mesenchymal stem cell (MSC)-derived soluble factors on the function of keratocytes, with a particular focus on the processes involved in wound healing, including keratocyte ..
  22. Lu L, Loi F, Nathan K, Lin T, Pajarinen J, Gibon E, et al. Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway. J Orthop Res. 2017;35:2378-2385 pubmed publisher
    ..selective inhibitor, significantly reduced bone mineralization in all co-cultures but most dramatically in the M1-MSC co-culture...
  23. Huang X, Ludke A, Dhingra S, Guo J, Sun Z, Zhang L, et al. Class II transactivator knockdown limits major histocompatibility complex II expression, diminishes immune rejection, and improves survival of allogeneic bone marrow stem cells in the infarcted heart. FASEB J. 2016;30:3069-82 pubmed publisher
    ..Allogeneic bone marrow mesenchymal stem cell (MSC) differentiation increases major histocompatibility complex II (MHC II) expression, inducing transition from ..
  24. Caroti C, Ahn H, Salazar H, Joseph G, Sankar S, Willett N, et al. A Novel Technique for Accelerated Culture of Murine Mesenchymal Stem Cells that Allows for Sustained Multipotency. Sci Rep. 2017;7:13334 pubmed publisher
    ..Our method for mMSC isolation and expansion will significantly improve the utility of this critical cell source in pre-clinical studies for the investigation of MSC mechanisms, therapies, and cell manufacturing strategies.
  25. Li X, Michaeloudes C, Zhang Y, Wiegman C, Adcock I, Lian Q, et al. Mesenchymal stem cells alleviate oxidative stress-induced mitochondrial dysfunction in the airways. J Allergy Clin Immunol. 2017;: pubmed publisher
    ..iPSC-MSC-conditioned medium or transwell cocultures with iPSC-MSCs reduced CSM-induced mitochondrial ROS but not ΔΨm or ..
  26. Lee S, Chong J, Min S, Bak S, Kim K. Are Adipose-Derived Stem Cells From Liver Falciform Ligaments Another Possible Source of Mesenchymal Stem Cells?. Cell Transplant. 2017;26:855-866 pubmed publisher
    ..Cells were cultivated in MSC culture medium...
  27. Maffioli E, Nonnis S, Angioni R, Santagata F, Calì B, Zanotti L, et al. Proteomic analysis of the secretome of human bone marrow-derived mesenchymal stem cells primed by pro-inflammatory cytokines. J Proteomics. 2017;166:115-126 pubmed publisher
    Mesenchymal stem cells (MSC) represent an impressive opportunity in term of regenerative medicine and immunosuppressive therapy...
  28. Reyes B, Coca M, Codinach M, López Lucas M, Del Mazo Barbara A, Caminal M, et al. Assessment of biodistribution using mesenchymal stromal cells: Algorithm for study design and challenges in detection methodologies. Cytotherapy. 2017;19:1060-1069 pubmed publisher
    ..A decision tree was defined based on the model chosen: (i) small immunodeficient animals receiving heterologous MSC products for assessing biodistribution and other safety aspects and (ii) large animals receiving homologous labeled ..
  29. Yang X, Yang J, Li X, Ma W, Zou H. Bone marrow-derived mesenchymal stem cells inhibit T follicular helper cell in lupus-prone mice. Lupus. 2018;27:49-59 pubmed publisher
    ..Conclusions BM-MSCs could effectively inhibit the differentiation of Tfh cells both in vitro and in vivo. BM-MSC treatment could relieve lupus nephritis, which indicates that BM-MSCs might be a promising therapeutic method for ..
  30. Szychlinska M, Stoddart M, D Amora U, Ambrosio L, Alini M, Musumeci G. Mesenchymal Stem Cell-Based Cartilage Regeneration Approach and Cell Senescence: Can We Manipulate Cell Aging and Function?. Tissue Eng Part B Rev. 2017;23:529-539 pubmed publisher
    ..reasons as follows: aging of MSCs, which determines the loss of cell proliferative and differentiation capacity and MSC-derived chondrocyte hypertrophic differentiation, which limits the use of these cells in cartilage tissue ..
  31. Choi J, Shin S, Lee C, Lee J, Seo H, Lim S, et al. Rapid Induction of Osteogenic Markers in Mesenchymal Stem Cells by Adipose-Derived Stromal Vascular Fraction Cells. Cell Physiol Biochem. 2017;44:53-65 pubmed publisher
    ..we sought to determine whether SVF implantation into impaired tissue affects endogenous mesenchymal stem cell (MSC) differentiation; MSCs can differentiate into a variety of cell types, and they have a strong regenerative capacity ..
  32. Anton N, Mulji N, Howley L, Yurco A, Tobben D, Bean E, et al. Effects of a novel mental skills curriculum on surgical novices' attention. J Surg Res. 2017;219:86-91 pubmed publisher
    ..Mental skills may enhance attention management and increase SAC. The purpose of this study was to determine the efficacy of a novel mental skills curriculum (MSC) to enhance novices' attention management.
  33. Wang D, Wang S, Huang S, Zhang Z, Yuan X, Feng X, et al. Serum IFN-γ Predicts the Therapeutic Effect of Mesenchymal Stem Cells Transplantation in Systemic Lupus Erythematosus Patients. Stem Cells Transl Med. 2017;6:1777-1785 pubmed publisher
    ..UC MSC functional molecules were assessed by real-time polymerase chain reaction, and the signaling pathways were analyzed ..
  34. Wang S, Li X, Xu M, Wang J, Zhao R. Reduced adipogenesis after lung tumor exosomes priming in human mesenchymal stem cells via TGFβ signaling pathway. Mol Cell Biochem. 2017;435:59-66 pubmed publisher
    ..be internalized by human adipose tissue-derived mesenchymal stem cells (hAD-MSCs) and significantly inhibited hAD-MSC adipogenesis as demonstrated by Oil Red O staining and decreased expression of adipogenic-specific genes...
  35. Ribeiro A, Ritter T, Griffin M, Ceredig R. Development of a flow cytometry-based potency assay for measuring the in vitro immunomodulatory properties of mesenchymal stromal cells. Immunol Lett. 2016;177:38-46 pubmed publisher
    Human bone marrow-derived mesenchymal stromal/stem cells (MSC) have well-documented modulatory effects on multiple immune cell types...
  36. Marsh H, Pekrun R, Murayama K, Arens A, Parker P, Guo J, et al. An Integrated Model of Academic Self-Concept Development: Academic Self-Concept, Grades, Test Scores, and Tracking Over 6 Years. Dev Psychol. 2017;: pubmed publisher
    ..Relations among math self-concept (MSC), school grades, test scores, and school-level contextual effects over 6 years, from the end of primary school ..
  37. Oloyo A, Ambele M, Pepper M. Contrasting Views on the Role of Mesenchymal Stromal/Stem Cells in Tumour Growth: A Systematic Review of Experimental Design. Adv Exp Med Biol. 2017;: pubmed publisher
    ..the sources and types of cancer cells and MSCs were considered together with modes of cancer induction and MSC administration. 56% of all 338 experiments reported that MSCs promote tumour growth...
  38. Steiner D, Köhn K, Beier J, Sturzl M, Horch R, Arkudas A. Cocultivation of Mesenchymal Stem Cells and Endothelial Progenitor Cells Reveals Antiapoptotic and Proangiogenic Effects. Cells Tissues Organs. 2017;204:218-227 pubmed publisher
    ..We could show that T17b EPCs stimulated MSC proliferation but not vice versa. On the other hand, MSCs promoted the cell survival of EPCs...
  39. Silva L, Cruz F, Morales M, Weiss D, Rocco P. Magnetic targeting as a strategy to enhance therapeutic effects of mesenchymal stromal cells. Stem Cell Res Ther. 2017;8:58 pubmed publisher
    ..It is known that the success of MSC-based therapies depends primarily on effective cell delivery to the target site where they will secrete vesicles ..
  40. Fujii S, Miura Y, Fujishiro A, Shindo T, Shimazu Y, Hirai H, et al. GVHD amelioration by human bone marrow mesenchymal stromal/stem cell-derived extracellular vesicles is associated with peripheral preservation of naive T cell populations. Stem Cells. 2017;: pubmed publisher
    ..We show here that BM-MSC-derived extracellular vesicles (EVs) recapitulated the therapeutic effects of BM-MSCs against aGVHD...
  41. Maroni G, Tkachuk V, Egorov A, Morelli M, Luongo R, Levantini E, et al. Prep1 prevents premature adipogenesis of mesenchymal progenitors. Sci Rep. 2017;7:15573 pubmed publisher
    ..differentiation since its down-regulation (DR) in both ex vivo bone marrow-derived mesenchymal stromal cells (MSC) and in vitro 3T3-L1 preadipocytes significantly increases their adipogenic differentiation ability...
  42. Sui B, Hu C, Liu A, Zheng C, Xuan K, Jin Y. Stem cell-based bone regeneration in diseased microenvironments: Challenges and solutions. Biomaterials. 2017;: pubmed publisher
    ..to jumpstart and facilitate bone healing, with immense regenerative potential in both pharmacology-based endogenous MSC rescue/mobilization in skeletal diseases and emerging application of MSC transplantation in bone tissue engineering ..
  43. Sundaram B, Cherian A, Kumar S. 3D Decellularized Native Extracellular Matrix Scaffold for In Vitro Culture Expansion of Human Wharton's Jelly-Derived Mesenchymal Stem Cells (hWJ MSCs). Methods Mol Biol. 2017;: pubmed publisher
    ..this chapter, we have elucidated the protocol for the preparation of a native extracellular matrix scaffold by decellularization of the MSC sheet and thereof culture expansion and characterization of human Wharton's jelly-derived MSCs.
  44. Egger D, Schwedhelm I, Hansmann J, Kasper C. Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor. Bioengineering (Basel). 2017;4: pubmed publisher
    ..Hence, the large scale formation and cultivation of MSC aggregates is highly desirable...
  45. Mazor M, Cesaro A, Ali M, Best T, Lespessaille E, Toumi H. Progenitor Cells from Cartilage: Grade Specific Differences in Stem Cell Marker Expression. Int J Mol Sci. 2017;18: pubmed publisher
    Recent research has confirmed the presence of Mesenchymal stem cell (MSC)-like progenitors (MPC) in both normal and osteoarthritic cartilage...
  46. Lin C, Li N, Cheng H, Yen M. Oxidative stress induces imbalance of adipogenic/osteoblastic lineage commitment in mesenchymal stem cells through decreasing SIRT1 functions. J Cell Mol Med. 2017;: pubmed publisher
    ..However, specific mechanisms of how ROS results in alterations on MSC differentiation capacity have been inconsistently reported...
  47. Sharma S, Fuchsluger T, Ahmad S, Katikireddy K, Armant M, Dana R, et al. Comparative analysis of human-derived feeder layers with 3T3 fibroblasts for the ex vivo expansion of human limbal and oral epithelium. Stem Cell Rev. 2012;8:696-705 pubmed publisher
    ..epithelium was co-cultured with mouse 3T3 fibroblasts, human dermal fibroblasts (DF), human mesenchymal stem cells (MSC), and with no feeder cells (NF)...
  48. Yates C, Nuschke A, Rodrigues M, Whaley D, Dechant J, Taylor D, et al. Improved Transplanted Stem Cell Survival in a Polymer Gel Supplemented With Tenascin C Accelerates Healing and Reduces Scarring of Murine Skin Wounds. Cell Transplant. 2017;26:103-113 pubmed publisher
    ..Many studies have found that despite the promise of MSC therapy, cell survival upon implant is highly limited and greatly reduces the therapeutic utility of MSCs...
  49. Schnapper A, Christmann A, Knudsen L, Rahmanian P, Choi Y, Zeriouh M, et al. Stereological assessment of the blood-air barrier and the surfactant system after mesenchymal stem cell pretreatment in a porcine non-heart-beating donor model for lung transplantation. J Anat. 2017;: pubmed publisher
    ..Thus, MSC administration might represent a promising pretreatment strategy for NHBD organs...
  50. Waghray M, Yalamanchili M, Dziubinski M, Zeinali M, Erkkinen M, Yang H, et al. GM-CSF Mediates Mesenchymal-Epithelial Cross-talk in Pancreatic Cancer. Cancer Discov. 2016;6:886-99 pubmed publisher
    ..In this study, we provide the first identification and characterization of mesenchymal stem cells (MSC) within the human PDA microenvironment, highlighting the heterogeneity of the fibroblast population...
  51. Kim A, Yu H, Lim J, Ryu C, Kim Y, Heo J, et al. Improved efficacy and in vivo cellular properties of human embryonic stem cell derivative in a preclinical model of bladder pain syndrome. Sci Rep. 2017;7:8872 pubmed publisher
    ..Mesenchymal stem cell (MSC) therapy is a promising approach to treat incurable IC/BPS...
  52. Ren T, Piperdi S, Koirala P, Park A, Zhang W, Ivenitsky D, et al. CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression. Oncotarget. 2017;8:87848-87859 pubmed publisher
    Osteosarcoma is a cancer whose cell of origin lies in the differentiation pathway between the mesenchymal stem cell (MSC) and the osteoblast (OB)...
  53. Feng J, Jing J, Li J, Zhao H, Punj V, Zhang T, et al. BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice. Development. 2017;144:2560-2569 pubmed publisher
    ..We first identified the MSC population supporting mouse molar root growth as Gli1+ cells...
  54. M J C, J P W, C P P, A S, F E, S L W, et al. Inducing chondrogenesis in MSC/chondrocyte co-cultures using exogenous TGF-β: a mathematical model. J Theor Biol. 2017;: pubmed publisher
    ..Finally, we use the model to demonstrate the potential advantages of adopting a hybrid strategy where exogenous TGF-β is added to a co-culture of MSCs and chondrocytes, as compared to using either strategy 1 or 2 in isolation...
  55. Xia W, Hou M. Macrophage migration inhibitory factor rescues mesenchymal stem cells from doxorubicin-induced senescence though the PI3K-Akt signaling pathway. Int J Mol Med. 2017;: pubmed publisher
    ..Mesenchymal stem cell (MSC)-based therapies have had positive outcomes in the treatment of DOXO-induced cardiac damage; however, DOXO exerts ..
  56. Brooks A, Futrega K, Liang X, Hu X, Liu X, Crawford D, et al. Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells. Stem Cells Transl Med. 2017;: pubmed publisher
    ..Optimization could be accelerated through specific understanding of MSC distribution in vivo, long-term viability, as well as their biological fate...
  57. Eslani M, Putra I, Shen X, Hamouie J, Afsharkhamseh N, Besharat S, et al. Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1. Invest Ophthalmol Vis Sci. 2017;58:5507-5517 pubmed publisher
    To evaluate the angiogenic properties of corneal derived mesenchymal stromal cells (Co-MSC).
  58. Ni K, Liu M, Zheng J, Wen L, Chen Q, Xiang Z, et al. PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice. Am J Respir Cell Mol Biol. 2017;: pubmed publisher
    Pulmonary fibrosis is a chronic progressive lung disease with few treatments. Human mesenchymal stem cells (MSC) have been shown to be beneficial to pulmonary fibrosis as they have the immunomodulatory capacity...
  59. Chen C, Lin W, Huang L, Chou H. Human mesenchymal stem cells ameliorate experimental pulmonary hypertension induced by maternal inflammation and neonatal hyperoxia in rats. Oncotarget. 2017;8:82366-82375 pubmed publisher
    ..Human MSC transplantation in LPS- and O2-treated rats reduced the MWT, RV:LV thickness ratio, and β-MHC and TLR4 ..
  60. Pan X, Zhu L, Yao X, Liu J, Li Z, Yang J, et al. Development of a tree shrew metabolic syndrome model and use of umbilical cord mesenchymal stem cell transplantation for treatment. Cytotechnology. 2016;68:2449-2467 pubmed
    ..We used tree shrew umbilical cord mesenchymal stem cell (TS-UC-MSC) transplantation for the treatment of metabolic syndrome to demonstrate the clinical application of these stem ..
  61. da Silva Meirelles L, de Deus Wagatsuma V, Malta T, Bonini Palma P, Araujo A, Panepucci R, et al. The gene expression profile of non-cultured, highly purified human adipose tissue pericytes: Transcriptomic evidence that pericytes are stem cells in human adipose tissue. Exp Cell Res. 2016;349:239-254 pubmed publisher
    ..that can give rise to mesenchymal stromal cells (MSCs) when culture-expanded, and are postulated to give rise to MSC-like cells during tissue repair in vivo...
  62. Ranganath S, Tong Z, Levy O, Martyn K, Karp J, Inamdar M. Controlled Inhibition of the Mesenchymal Stromal Cell Pro-inflammatory Secretome via Microparticle Engineering. Stem Cell Reports. 2016;6:926-39 pubmed publisher
    ..However, controlling the MSC secretome post-transplantation is considered a major challenge that hinders their clinical efficacy...