SLC25A37

Summary

Gene Symbol: SLC25A37
Description: solute carrier family 25 member 37
Alias: HT015, MFRN, MFRN1, MSC, MSCP, PRO1278, PRO1584, PRO2217, mitoferrin-1, mitochondrial iron transporter 1, mitochondrial solute carrier protein, mitoferrin, solute carrier family 25 (mitochondrial iron transporter), member 37
Species: human
Products:     SLC25A37

Top Publications

  1. He X, Wang X, Fang J, Chang Y, Ning N, Guo H, et al. The genus Achyranthes: A review on traditional uses, phytochemistry, and pharmacological activities. J Ethnopharmacol. 2017;203:260-278 pubmed publisher
    ..also obtained from International Plant Names Index, Chinese Pharmacopoeia, Chinese herbal classic books, PhD and MSc dissertations, etc...
  2. Anyanwu G, Nisar ur Rehman -, Onyeneke C, Rauf K. Medicinal plants of the genus Anthocleista--A review of their ethnobotany, phytochemistry and pharmacology. J Ethnopharmacol. 2015;175:648-67 pubmed publisher
    ..Scopus, PubChem and other web sources such as The Plant List, Kew Botanical Garden and PROTA) and books, PhD and MSc dissertations for un-published resources...
  3. Zhang L, Li Y, Guan C, Tian S, Lv X, Li J, et al. Therapeutic effect of human umbilical cord-derived mesenchymal stem cells on injured rat endometrium during its chronic phase. Stem Cell Res Ther. 2018;9:36 pubmed publisher
    ..The cell proliferation marker Ki-67 had a positive expression in the injured endometrium after UC-MSC transplantation...
  4. He X, Bai Y, Zhao Z, Wang X, Fang J, Huang L, et al. Local and traditional uses, phytochemistry, and pharmacology of Sophora japonica L.: A review. J Ethnopharmacol. 2016;187:160-82 pubmed publisher
    ..was also obtained from local classic herbal literature, government reports, conference papers, as well as PhD and MSc dissertations...
  5. Manzini B, da Silva Santos Duarte A, Sankaramanivel S, Ramos A, Latuf Filho P, Escanhoela C, et al. Useful properties of undifferentiated mesenchymal stromal cells and adipose tissue as the source in liver-regenerative therapy studied in an animal model of severe acute fulminant hepatitis. Cytotherapy. 2015;17:1052-65 pubmed publisher
    ..This study aimed to analyze whether undifferentiated mesenchymal stromal cells (U-MSCs) or MSC-derived hepatocyte-like cells (DHLCs) from adipose tissue (AT), umbilical cord blood (UCB) and bone marrow (BM) ..
  6. Liu S, Tang Z, Liao Z, Cui C, Liu H, Liang Y, et al. The chemistry and pharmacology of Ligularia przewalskii: A review. J Ethnopharmacol. 2018;219:32-49 pubmed publisher
    ..The information on LP will be helpful in providing and identifying its therapeutic potential and economic value for its use as a new medicine in the future. ..
  7. Souza M, Silva J, Pádua T, Torres N, Antunes M, Xisto D, et al. Mesenchymal stromal cell therapy attenuated lung and kidney injury but not brain damage in experimental cerebral malaria. Stem Cell Res Ther. 2015;6:102 pubmed publisher
    ..Mesenchymal stromal cells (MSC) confer host resistance against malaria; however, thus far, no study has evaluated the therapeutic effects of MSC ..
  8. Peng W, Liu Y, Wu N, Sun T, He X, Gao Y, et al. Areca catechu L. (Arecaceae): a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology. J Ethnopharmacol. 2015;164:340-56 pubmed publisher
    ..A literature search was performed on A. catechu based on classic books of herbal medicine, PhD. and MSc. dissertations, government reports, the state and local drug standards, scientific databases including Pubmed, ..
  9. Sala E, Genua M, Petti L, Anselmo A, Arena V, Cibella J, et al. Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine. Gastroenterology. 2015;149:163-176.e20 pubmed publisher
    ..MSCs were reported to reduce colitis in mice; we investigated whether MSC localization to the intestine and production of paracrine factors, including tumor necrosis factor-induced protein ..

More Information

Publications153 found, 100 shown here

  1. Guo Y, Yin T, Wang X, Zhang F, Pan G, Lv H, et al. Traditional uses, phytochemistry, pharmacology and toxicology of the genus Cimicifuga: A review. J Ethnopharmacol. 2017;209:264-282 pubmed publisher
    ..of Science, China Knowledge Resource Integrated Database), Chinese herbal classics, ethnobotanical books, PhD and MSc dissertations, Chinese Pharmacopoeia, published articles in peer-reviewed journals, local magazines, and ..
  2. He X, Fang J, Huang L, Wang J, Huang X. Sophora flavescens Ait.: Traditional usage, phytochemistry and pharmacology of an important traditional Chinese medicine. J Ethnopharmacol. 2015;172:10-29 pubmed publisher
    ..was also acquired from local classic herbal literature, conference papers, government reports, and PhD and MSc dissertations...
  3. Bian P, Ye C, Zheng X, Yang J, Ye W, Wang Y, et al. Mesenchymal stem cells alleviate Japanese encephalitis virus-induced neuroinflammation and mortality. Stem Cell Res Ther. 2017;8:38 pubmed publisher
    ..b>MSC treatment reduced JEV-induced mortality and improved the recovery from JE in our mouse model...
  4. Tyndall A, van Laar J. Stem cell transplantation and mesenchymal cells to treat autoimmune diseases. Presse Med. 2016;45:e159-69 pubmed publisher
    ..Mesenchymal stromal cells (MSC), often incorrectly called stem cells, have been the intense focus of in vitro studies and animal models of ..
  5. An S, Jang Y, Lim H, Han J, Lee J, Lee G, et al. Milk Fat Globule-EGF Factor 8, Secreted by Mesenchymal Stem Cells, Protects Against Liver Fibrosis in Mice. Gastroenterology. 2017;152:1174-1186 pubmed publisher
    ..We analyzed the effects of MSC secretomes and potential anti-fibrotic proteins on transforming growth factor β 1 (TGFβ1)-mediated activation ..
  6. Levato R, Webb W, Otto I, Mensinga A, Zhang Y, van Rijen M, et al. The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells. Acta Biomater. 2017;61:41-53 pubmed publisher
    ..By combining ACPC- and MSC-laden bioinks, a bioprinted model of articular cartilage was generated, consisting of defined superficial and deep ..
  7. Yang W, Zheng H, Wang Y, Lian F, Hu Z, Xue S. Nesprin-1 has key roles in the process of mesenchymal stem cell differentiation into cardiomyocyte-like cells in vivo and in vitro. Mol Med Rep. 2015;11:133-42 pubmed publisher
    ..Surface-associated antigens of MSCs were detected by flow cytometry. MSC differentiation was induced by treatment with 10 µmol/l 5-azacytidine...
  8. Zhu A, Zhang T, Wang Q. The phytochemistry, pharmacokinetics, pharmacology and toxicity of Euphorbia semen. J Ethnopharmacol. 2018;227:41-55 pubmed publisher
    ..In this manuscript, a number of books, PhD and MSc dissertations, and Chinese Pharmacopeia were also used as references...
  9. Zhu B, Zhang Q, Hua J, Cheng W, Qin L. The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review. J Ethnopharmacol. 2018;226:143-167 pubmed publisher
    ..Further research on the comprehensive evaluation of medicinal quality, the understanding of multi-target network pharmacology of A. macrocephala, as well as its long-term in vivo toxicity and clinical efficacy is recommended. ..
  10. Xu L, Wang S, Wang D, Ma L, Chen Z, Chen Q, et al. Adipose-derived stromal cells resemble bone marrow stromal cells in hepatocyte differentiation potential in vitro and in vivo. World J Gastroenterol. 2017;23:6973-6982 pubmed publisher
    ..There was no significant difference between the two MSC groups...
  11. Du T, Cheng J, Zhong L, Zhao X, Zhu J, Zhu Y, et al. The alleviation of acute and chronic kidney injury by human Wharton's jelly-derived mesenchymal stromal cells triggered by ischemia-reperfusion injury via an endocrine mechanism. Cytotherapy. 2012;14:1215-27 pubmed publisher
    The effects of human Wharton's jelly-derived mesenchymal stromal cells (WJ-MSC) on acute and chronic kidney injury induced by ischemia-reperfusion injury (IRI) were assessed...
  12. Nong K, Wang W, Niu X, Hu B, Ma C, Bai Y, et al. Hepatoprotective effect of exosomes from human-induced pluripotent stem cell-derived mesenchymal stromal cells against hepatic ischemia-reperfusion injury in rats. Cytotherapy. 2016;18:1548-1559 pubmed publisher
    ..hiPSCs were efficiently induced into hiPSC-MSCs with typical MSC characteristics...
  13. Chen H, Xiang H, Xu W, Li M, Yuan J, Liu J, et al. Manganese Superoxide Dismutase Gene-Modified Mesenchymal Stem Cells Attenuate Acute Radiation-Induced Lung Injury. Hum Gene Ther. 2017;28:523-532 pubmed publisher
    ..factor transforming growth factor-?1, and the oxidative stress factor (hydroxyproline) were evaluated after MnSOD-MSC transplant...
  14. Sir G, Goker Bagca B, Yigitturk G, Cavusoğlu T, Biray Avci C, Gunduz C, et al. Antagonistic Effect of Oxytocin and Tacrolimus Combination on Adipose Tissue - Derived Mesenchymal Stem Cells: Antagonistic effect of oxytocin and tacrolimus. Biomed Pharmacother. 2018;97:1173-1181 pubmed publisher
    ..cytotoxic, apoptotic and morphological effects of FK506, an immunosuppressive agent, on adipose tissue - derived MSC (ADMSC) which has the potential to be used for immune suppression...
  15. Guo D, Zhu X, Li Q, Liu G, Ruan G, Pang R, et al. Efficacy and mechanisms underlying the effects of allogeneic umbilical cord mesenchymal stem cell transplantation on acute radiation injury in tree shrews. Cytotechnology. 2018;: pubmed publisher
    ..IL-8 and the fibrosis-related factors PDGF-BB, PDGF-AA, TGF-?1, IGFBP-2, and IGFBP-4 were significantly lower in UC-MSC-injected animals...
  16. Wang L, Yu Y, Guan H, Qiao C. Effect of Human Umbilical Cord Mesenchymal Stem Cell Transplantation in a Rat Model of Preeclampsia. Reprod Sci. 2016;23:1058-70 pubmed publisher
    To test the effects of human umbilical cord mesenchymal stem cell (HU-MSC) transplantation on reversing preeclampsia (PE) symptoms in a lipopolysaccharide (LPS)-induced rat PE model...
  17. Park H, Shin J, Kim H, Oh S, Song S, Lee P. Mesenchymal stem cells stabilize the blood-brain barrier through regulation of astrocytes. Stem Cell Res Ther. 2015;6:187 pubmed publisher
    ..In the present study, we investigated whether mesenchymal stem cell (MSC) treatment might modulate reactive astrocytes and thus stabilize BBB integrity through vascular endothelial growth ..
  18. He X, Wang X, Fang J, Zhao Z, Huang L, Guo H, et al. Bletilla striata: Medicinal uses, phytochemistry and pharmacological activities. J Ethnopharmacol. 2017;195:20-38 pubmed publisher
    ..Information was also obtained from The Plant List, Chinese pharmacopoeia, Chinese herbal classics books, PhD and MSc dissertations, etc...
  19. Li J, Dai Y, Zhu H, Jiang Y, Zhang S. Endometriotic mesenchymal stem cells significantly promote fibrogenesis in ovarian endometrioma through the Wnt/β-catenin pathway by paracrine production of TGF-β1 and Wnt1. Hum Reprod. 2016;31:1224-35 pubmed publisher
    ..Additionally, fibrogenic effects of Ecto-MSC CM treatment on endometriotic implants were analyzed using a xenograft model of endometriosis in immunodeficient ..
  20. Lu F, Wang F, Chen Z, Huang H. Effect of mesenchymal stem cells on small intestinal injury in a rat model of acute necrotizing pancreatitis. Stem Cell Res Ther. 2017;8:12 pubmed publisher
    ..In conclusion, MSC therapy could alleviate small intestinal injury in rats with ANP, the mechanism of which might be related to ..
  21. Saito A, Ooki A, Nakamura T, Onodera S, Hayashi K, Hasegawa D, et al. Targeted reversion of induced pluripotent stem cells from patients with human cleidocranial dysplasia improves bone regeneration in a rat calvarial bone defect model. Stem Cell Res Ther. 2018;9:12 pubmed publisher
    ..At present, as a therapeutic strategy for osteoporosis, mesenchymal stem cell (MSC) transplantation therapy is performed in addition to drug therapy...
  22. Chadid T, Morris A, Surowiec A, Robinson S, Sasaki M, Galipeau J, et al. Reversible secretome and signaling defects in diabetic mesenchymal stem cells from peripheral arterial disease patients. J Vasc Surg. 2018;: pubmed publisher
    ..Both BM- and ATD-dMSCs had typical MSC surface marker expression and similar expansion profiles, and they did not express EGF in their secretome...
  23. Cheng G, Wang X, Li Y, He L. Let-7a-transfected mesenchymal stem cells ameliorate monocrotaline-induced pulmonary hypertension by suppressing pulmonary artery smooth muscle cell growth through STAT3-BMPR2 signaling. Stem Cell Res Ther. 2017;8:34 pubmed publisher
    ..Here, we investigated the effect of MSC-based let-7a for PAH...
  24. Gramlich O, Burand A, Brown A, Deutsch R, Kuehn M, Ankrum J. Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy. Sci Rep. 2016;6:26463 pubmed publisher
    The ability to use mesenchymal stromal cells (MSC) directly out of cryostorage would significantly reduce the logistics of MSC therapy by allowing on-site cryostorage of therapeutic doses of MSC at hospitals and clinics...
  25. Zhang H, Liu S, Zhu B, Xu Q, Ding Y, Jin Y. Composite cell sheet for periodontal regeneration: crosstalk between different types of MSCs in cell sheet facilitates complex periodontal-like tissue regeneration. Stem Cell Res Ther. 2016;7:168 pubmed
    ..However, given the complexity in periodontal structure, the regeneration methods using a single species of MSC could not fulfill the requirement for periodontal regeneration...
  26. Su N, Gao P, Wang K, Wang J, Zhong Y, Luo Y. Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction. Biomaterials. 2017;141:74-85 pubmed publisher
    ..to provide environment to regulate cell viability, proliferation or differentiation, the therapeutic effects of MSC-material constructs may result from the secretion of immunomodulatory and angiogenic cytokines from MSCs...
  27. Freeman B, Ogle B. Viral-mediated fusion of mesenchymal stem cells with cells of the infarcted heart hinders healing via decreased vascularization and immune modulation. Sci Rep. 2016;6:20283 pubmed publisher
    ..Specifically, MSCs transfected with VSVG (MSC-VSVG) had the lowest mean fold increase in fractional area change (FAC) and cardiac output (CO)...
  28. Du W, Chi Y, Yang Z, Li Z, Cui J, Song B, et al. Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta. Stem Cell Res Ther. 2016;7:163 pubmed
    ..adipose tissue (AMSCs), perinatal umbilical cord (UMSCs), and placental chorionic villi (PMSCs), and studied their "MSC identity" by flow cytometry and in-vitro trilineage differentiation assay...
  29. Tang Q, Luo C, Lu B, Fu Q, Yin H, Qin Z, et al. Thermosensitive chitosan-based hydrogels releasing stromal cell derived factor-1 alpha recruit MSC for corneal epithelium regeneration. Acta Biomater. 2017;61:101-113 pubmed publisher
    ..Therefore, SDF-1 alpha/CHI hydrogel complexes could be a practical application for clinical therapy. ..
  30. Qi J, Zhou Y, Jiao Z, Wang X, Zhao Y, Li Y, et al. Exosomes Derived from Human Bone Marrow Mesenchymal Stem Cells Promote Tumor Growth Through Hedgehog Signaling Pathway. Cell Physiol Biochem. 2017;42:2242-2254 pubmed publisher
    ..Here, we, from the view of bone marrow MSC-derived exosomes, study the molecular mechanism of MSCs on the growth of human osteosarcoma and human gastric ..
  31. Samuel S, Ahmad R, Ramasamy T, Manan F, Kamarul T. Platelet rich concentrate enhances mesenchymal stem cells capacity to repair focal cartilage injury in rabbits. Injury. 2018;49:775-783 pubmed publisher
    ..PRC (n = 10), ii) MSCs (n = 10), or, iii) a combination of PRC and MSCs (PRC + MSC) (n = 10), all encapsulated in alginate. The left knee remained untreated (control)...
  32. Vallabhaneni H, Lynch P, Chen G, Park K, Liu Y, Goehe R, et al. High Basal Levels of ?H2AX in Human Induced Pluripotent Stem Cells Are Linked to Replication-Associated DNA Damage and Repair. Stem Cells. 2018;: pubmed publisher
    ..of DNA damage in human iPSC lines compared with their founder fibroblast line and derived mesenchymal stromal cell (MSC) lines using the phosphorylated histone variant, ?H2AX, as a marker of DNA damage...
  33. Deng W, Chen Q, Li X, Yuan Z, Li G, Ke D, et al. Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis. Int J Clin Exp Pathol. 2015;8:10555-64 pubmed
    ..transducer and activators of transcription (STAT) signaling using bone marrow (BM) mesenchymal stromal cells (MSC) in which being over-expressed with the aid of bispecific antibody (BiAb) and ultrasound-mediated microbubbles (MB)...
  34. Ulusoy C, Zibandeh N, Yıldırım S, Trakas N, Zisimopoulou P, Küçükerden M, et al. Dental follicle mesenchymal stem cell administration ameliorates muscle weakness in MuSK-immunized mice. J Neuroinflammation. 2015;12:231 pubmed publisher
    ..Around 5-10 % of MG patients show antibodies to muscle-specific tyrosine kinase (MuSK). Mesenchymal stem cell (MSC) administration has been shown to ameliorate muscle weakness in the experimental autoimmune myasthenia gravis (EAMG)..
  35. Zhu Q, Li X, Wang W, Hu J, Li P, Conley S, et al. Mesenchymal stem cell transplantation inhibited high salt-induced activation of the NLRP3 inflammasome in the renal medulla in Dahl S rats. Am J Physiol Renal Physiol. 2016;310:F621-F627 pubmed publisher
    ..The present study determined the response of the NLRP3 inflammasome to HS intake and the effect of MSC transplantation on the NLRP3 inflammasome in the renal medulla in Dahl S rats...
  36. Aikawa E, Fujita R, Asai M, Kaneda Y, Tamai K. Receptor for Advanced Glycation End Products-Mediated Signaling Impairs the Maintenance of Bone Marrow Mesenchymal Stromal Cells in Diabetic Model Mice. Stem Cells Dev. 2016;25:1721-1732 pubmed
    ..BM population, which was previously identified as a slow-cycling BM-MSC population, also decreased...
  37. Shu B, Zhao Y, Wang Y, Wang G, Shang X, Britt M, et al. Oleanolic Acid Enhances Mesenchymal Stromal Cell Osteogenic Potential by Inhibition of Notch Signaling. Sci Rep. 2017;7:7002 pubmed publisher
    ..But the mechanisms underlying OA-mediated mesenchymal stromal cell (MSC) osteogenic differentiation are not known...
  38. Seo N, Shirakura Y, Tahara Y, Momose F, Harada N, Ikeda H, et al. Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells. Nat Commun. 2018;9:435 pubmed publisher
    ..CD8+ T cells is observed in neovascular areas with high mesenchymal cell density, and tumour MSC depletion is associated with preferential engulfment of CD8+ T cell EVs in this setting...
  39. Nakatsuka R, Iwaki R, Matsuoka Y, Sumide K, Kawamura H, Fujioka T, et al. Identification and Characterization of Lineage(-)CD45(-)Sca-1(+) VSEL Phenotypic Cells Residing in Adult Mouse Bone Tissue. Stem Cells Dev. 2016;25:27-42 pubmed publisher
    ..15%, respectively. These BD VSELs expressed a variety of hematopoietic stem cell (HSC), mesenchymal stem cell (MSC), and endothelial cell markers...
  40. Li X, Liu L, Yang J, Yu Y, Chai J, Wang L, et al. Exosome Derived From Human Umbilical Cord Mesenchymal Stem Cell Mediates MiR-181c Attenuating Burn-induced Excessive Inflammation. EBioMedicine. 2016;8:72-82 pubmed publisher
    Mesenchymal stem cell (MSC)-derived exosomes have diverse functions in regulating wound healing and inflammation; however, the molecular mechanism of human umbilical cord MSC (hUCMSC)-derived exosomes in regulating burn-induced ..
  41. Islam A, Mbimba T, Younesi M, Akkus O. Effects of substrate stiffness on the tenoinduction of human mesenchymal stem cells. Acta Biomater. 2017;58:244-253 pubmed publisher
    ..Although the effects of substrate topography and modulus on MSC differentiation are well known with respect to osteogenesis and adipogenesis, there has been relatively little ..
  42. Kaplan A, Sackett K, Sumstad D, Kadidlo D, McKenna D. Impact of starting material (fresh versus cryopreserved marrow) on mesenchymal stem cell culture. Transfusion. 2017;57:2216-2219 pubmed publisher
    ..However, little is known about how cryopreservation affects marrow as starting material. The growth kinetics of MSC cultures derived from fresh versus cryopreserved marrow were compared.
  43. Peng H, Lu J, Jiang J, Cao J. Longitudinal Mechano-Sorptive Creep Behavior of Chinese Fir in Tension during Moisture Adsorption Processes. Materials (Basel). 2017;10: pubmed publisher
    ..at relative humidity (RH) isohume conditions and find the basic characteristics of mechano-sorptive (MS) creep (MSC), the tensile creep behaviors, "viscoelastic creep (VEC)" at equilibrium moisture content and MSC during adsorption ..
  44. Ge Q, Zhang H, Hou J, Wan L, Cheng W, Wang X, et al. VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms. Mol Med Rep. 2017;: pubmed publisher
    ..We have previously demonstrated that the adhesion between MSCs and EPCs is critical for MSC self?renewal and their multi?differentiation into osteoblasts and chondrocytes...
  45. Zhang M, Zhang H, Feng W, Wang Y, Yin S, Chen X, et al. [Endothelial progenitor cells promote osteogenic differentiation of marrow stromal cells in a paracrine manner]. Zhonghua Yi Xue Za Zhi. 2015;95:1253-7 pubmed
    ..EPCs secreted VEGF, TGFβ1, PDGF, IGF-1, SDF-1 and bFGF. MSC/EPC group formed more mineralized nodules than MSC group, and semi-quantitative results showed the optical density ..
  46. Molligan J, Mitchell R, Bhasin P, Lakhani A, Schon L, Zhang Z. Implantation of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells in Foot Fat Pad in Rats. Foot Ankle Int. 2015;36:1344-51 pubmed publisher
    ..On histologic testing, the area of fat pad units (FPUs) in the fat pads that received AT-MSC injections was greater than that in the control fat pads...
  47. Gómez M, Qin Q, Biancardi M, Galiguis J, Dumas C, MacLean R, et al. Characterization and Multilineage Differentiation of Domestic and Black-Footed Cat Mesenchymal Stromal/Stem Cells from Abdominal and Subcutaneous Adipose Tissue. Cell Reprogram. 2015;17:376-92 pubmed publisher
    ..Both domestic cat AB- and SQ-AMSCs showed important clonogenic ability and the minimal MSC immunophenotype as defined by the International Society for Cellular Therapy in humans...
  48. Chen P, Huang Y, Womer K. Effects of mesenchymal stromal cells on human myeloid dendritic cell differentiation and maturation in a humanized mouse model. J Immunol Methods. 2015;427:100-4 pubmed publisher
    ..Human DCs were differentiated from humanized mouse bone marrow cells during human MSC co-culture...
  49. Porta A, Bari V, Ranuzzi G, De Maria B, Baselli G. Assessing multiscale complexity of short heart rate variability series through a model-based linear approach. Chaos. 2017;27:093901 pubmed publisher
    We propose a multiscale complexity (MSC) method assessing irregularity in assigned frequency bands and being appropriate for analyzing the short time series...
  50. Roosens A, Asadian M, De Geyter N, Somers P, Cornelissen R. Complete Static Repopulation of Decellularized Porcine Tissues for Heart Valve Engineering: An in vitro Study. Cells Tissues Organs. 2017;: pubmed publisher
    ..of the interstitium, porcine valvular interstitial cells (VIC) and bone marrow-derived mesenchymal stem cells (BM-MSC) or adipose tissue-derived stem cells (ADSC) were used...
  51. Güldner A, Maron Gutierrez T, Abreu S, Xisto D, Senegaglia A, Barcelos P, et al. Expanded endothelial progenitor cells mitigate lung injury in septic mice. Stem Cell Res Ther. 2015;6:230 pubmed publisher
    ..of non-expanded EPCs (EPC-NEXP) with those of expanded EPCs (EPC-EXP) and mesenchymal stromal cells of human (MSC-HUMAN) and mouse (MSC-MICE) origin in experimental sepsis...
  52. Sharma A, Salmon M, Lu G, Su G, Pope N, Smith J, et al. Mesenchymal Stem Cells Attenuate NADPH Oxidase-Dependent High Mobility Group Box 1 Production and Inhibit Abdominal Aortic Aneurysms. Arterioscler Thromb Vasc Biol. 2016;36:908-18 pubmed publisher
    ..demonstrated a significant increase in HMGB1 production in C57BL/6 (wild-type [WT]) mice, which was attenuated by MSC treatment...
  53. Nitzsche F, Müller C, Lukomska B, Jolkkonen J, Deten A, Boltze J. Concise Review: MSC Adhesion Cascade-Insights into Homing and Transendothelial Migration. Stem Cells. 2017;35:1446-1460 pubmed publisher
    ..Local transplantation deposits MSC in spatial proximity to the lesion, but often requires invasive procedures...
  54. Yan F, Li X, Li N, Zhang R, Wang Q, Ru Y, et al. Immunoproapoptotic molecule scFv-Fdt-tBid modified mesenchymal stem cells for prostate cancer dual-targeted therapy. Cancer Lett. 2017;402:32-42 pubmed publisher
    ..Such engineered MSCs (MSC.scFv-Fdt-tBid) would home to tumor sites and release the fusion protein to induce the apoptosis of prostate cancer ..
  55. Barrera Ramirez J, Lavoie J, Maganti H, Stanford W, Ito C, Sabloff M, et al. Micro-RNA Profiling of Exosomes from Marrow-Derived Mesenchymal Stromal Cells in Patients with Acute Myeloid Leukemia: Implications in Leukemogenesis. Stem Cell Rev. 2017;13:817-825 pubmed publisher
    ..Known targets of mIRs that were significantly different in AML-derived MSC exosomes compared to controls were identified...
  56. Oliveira Sales E, Boim M. Mesenchymal stem cells and chronic renal artery stenosis. Am J Physiol Renal Physiol. 2016;310:F6-9 pubmed publisher
    ..This review addresses the effects of mesenchymal stem cells (MSC) in an experimental animal model of renovascular hypertension known as 2 kidney-1 clip (2K-1C)...
  57. Ruan G, Yao X, Liu J, He J, Li Z, Yang J, et al. Establishing a tree shrew model of systemic lupus erythematosus and cell transplantation treatment. Stem Cell Res Ther. 2016;7:121 pubmed publisher
    ..The combined intraperitoneal injection of pristane and LPS is the best way to induce SLE pathological changes. The pathological changes improved after UC-MSC treatment.
  58. Sang J, Shi X, Han B, Huang T, Huang X, Ren H, et al. Intraportal mesenchymal stem cell transplantation prevents acute liver failure through promoting cell proliferation and inhibiting apoptosis. Hepatobiliary Pancreat Dis Int. 2016;15:602-611 pubmed
    ..Intraportal injection was superior to other pathways for MSC transplantation...
  59. Jia Z, Liang Y, Xu X, Li X, Liu Q, Ou Y, et al. Isolation and characterisation of human mesenchymal stem cells derived from synovial fluid by magnetic activated cell sorting (MACS). Cell Biol Int. 2017;: pubmed publisher
    ..We have successfully purified hSF-MSCs using magnetic activated cell sorting (MACS) sorting using the MSC surface marker, CD90...
  60. Laranjeira P, Gomes J, Pedreiro S, Pedrosa M, Martinho A, Antunes B, et al. Human Bone Marrow-Derived Mesenchymal Stromal Cells Differentially Inhibit Cytokine Production by Peripheral Blood Monocytes Subpopulations and Myeloid Dendritic Cells. Stem Cells Int. 2015;2015:819084 pubmed publisher
    The immunosuppressive properties of mesenchymal stromal/stem cells (MSC) rendered them an attractive therapeutic approach for immune disorders and an increasing body of evidence demonstrated their clinical value...
  61. Kolf C, Song L, Helm J, Tuan R. Nascent osteoblast matrix inhibits osteogenesis of human mesenchymal stem cells in vitro. Stem Cell Res Ther. 2015;6:258 pubmed publisher
    ..the endosteal bone marrow surface are in close proximity to MSCs in the marrow stroma and thus may help to regulate MSC fate...
  62. Yousefifard M, NasiriNezhad F, Shardi Manaheji H, Janzadeh A, Hosseini M, Keshavarz M. Human bone marrow-derived and umbilical cord-derived mesenchymal stem cells for alleviating neuropathic pain in a spinal cord injury model. Stem Cell Res Ther. 2016;7:36 pubmed publisher
    ..Therefore, the present study aimed to determine the effect of stem cells derived from bone marrow (BM-MSC) and umbilical cord (UC-MSC) on neuropathic pain relief. A compression model was used to induce SCI in a rat model...
  63. Ciavarella C, Fittipaldi S, Pasquinelli G. CoCl2 Administration to Vascular MSC Cultures as an In Vitro Hypoxic System to Study Stem Cell Survival and Angiogenesis. Methods Mol Biol. 2016;1516:309-317 pubmed publisher
    ..In order to avoid the use of expensive facilities, we propose the application of a chemical hypoxia inducer, cobalt chloride. ..
  64. Mazzolini R, González N, Garcia Garijo A, Millanes Romero A, Peiro S, Smith S, et al. Snail1 transcription factor controls telomere transcription and integrity. Nucleic Acids Res. 2017;: pubmed publisher
    ..Fluorescence in situ hybridization (FISH) analysis indicates that Snail1-depleted mouse mesenchymal stem cells (MSC) have both a dramatic increase of telomere alterations and shorter telomeres...
  65. Gonzalez Perez F, Hernandez J, Heimann C, Phillips J, Udina E, Navarro X. Schwann cells and mesenchymal stem cells in laminin- or fibronectin-aligned matrices and regeneration across a critical size defect of 15 mm in the rat sciatic nerve. J Neurosurg Spine. 2017;:1-10 pubmed publisher
    ..In contrast, animals that underwent repair with MSC-aligned constructs had only 90% regeneration success, and those implanted with acellular bridges had only 75% ..
  66. Störmann P, Kupsch J, Kontradowitz K, Leiblein M, Verboket R, Seebach C, et al. Cultivation of EPC and co-cultivation with MSC on β-TCP granules in vitro is feasible without fibronectin coating but influenced by scaffolds' design. Eur J Trauma Emerg Surg. 2018;: pubmed publisher
    ..5 × 105 EPC, or 5 × 105 MSC or a combination of each 2.5 × 105 cells was seeded onto the granules...
  67. Ho S, Murphy K, Binder B, Vissers C, Leach J. Increased Survival and Function of Mesenchymal Stem Cell Spheroids Entrapped in Instructive Alginate Hydrogels. Stem Cells Transl Med. 2016;5:773-81 pubmed publisher
    Mesenchymal stem cell (MSC)-based therapies are under broad investigation for applications in tissue repair but suffer from poor cell persistence and engraftment upon transplantation...
  68. Wang B, Lee W, Huang B, Zhang J, Wu T, Jiang X, et al. Secretome of Human Fetal Mesenchymal Stem Cell Ameliorates Replicative Senescen. Stem Cells Dev. 2016;25:1755-1766 pubmed
    Autologous mesenchymal stem cells (MSC) are widely used cell source for cell-based tissue repair and regeneration, but replicative senescence and the associated loss of cellular activity during in vitro expansion limit their therapeutic ..
  69. Harris V, Vyshkina T, Sadiq S. Clinical safety of intrathecal administration of mesenchymal stromal cell-derived neural progenitors in multiple sclerosis. Cytotherapy. 2016;18:1476-1482 pubmed publisher
    ..immunoregulatory and trophic properties of neural progenitors derived from bone marrow mesenchymal stromal cells (MSC-NPs) and established that cells derived from MS and non-MS patients alike were therapeutically viable...
  70. Li C, Leng Y, Zhao B, Gao C, Du F, Jin N, et al. Human iPSC-MSC-Derived Xenografts Modulate Immune Responses by Inhibiting the Cleavage of Caspases. Stem Cells. 2017;35:1719-1732 pubmed publisher
    ..However, the effects of iPSC-MSCs on T cells phenotypes in vivo remain unclear. We established an iPSC-MSC-transplanted host versus graft reaction mouse model using subcapsular kidney injection...
  71. Facchetti G, Petrella F, Spaggiari L, Rimoldi I. Malignant Pleural Mesothelioma: State of the art and advanced cell therapy. Eur J Med Chem. 2017;142:266-270 pubmed publisher
    ..Alternative strategies to the commonly used combination-therapy resulted from the use of Mesenchymal Stromal Cells (MSC) widely used in the field of regenerative medicine and recently proposed as natural carriers for a selective ..
  72. Maruyama C, Leigh N, Nelson J, McCall A, Mellas R, Lei P, et al. Stem Cell-Soluble Signals Enhance Multilumen Formation in SMG Cell Clusters. J Dent Res. 2015;94:1610-7 pubmed publisher
    ..However, the hHF-MSC conditioned medium enhanced cell organization and multilumen formation, indicating that soluble signals secreted by ..
  73. Owen A, Newsome P. Mesenchymal stromal cell therapy in liver disease: opportunities and lessons to be learnt?. Am J Physiol Gastrointest Liver Physiol. 2015;309:G791-800 pubmed publisher
    ..Mesenchymal stem cells (MSC) offer an opportunity to both treat liver inflammatory damage, as well as reverse some of the changes that occur ..
  74. Doeppner T, Herz J, Görgens A, Schlechter J, Ludwig A, Radtke S, et al. Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression. Stem Cells Transl Med. 2015;4:1131-43 pubmed publisher
    ..neurological impairment and brain remodeling, we systematically compared the effects of mesenchymal stem cell (MSC)-derived EVs (MSC-EVs) with MSCs that were i.v...
  75. Yu B, Sondag G, Malcuit C, Kim M, Safadi F. Macrophage-Associated Osteoactivin/GPNMB Mediates Mesenchymal Stem Cell Survival, Proliferation, and Migration Via a CD44-Dependent Mechanism. J Cell Biochem. 2016;117:1511-21 pubmed publisher
    ..The objective of this study was to investigate the potential role of OA/GPNMB in macrophage-induced MSC function...
  76. Feng N, Hao G, Yang F, Qu F, Zheng H, Liang S, et al. Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin-associated inhibitor expression and neural apoptosis. Exp Ther Med. 2016;11:1595-1600 pubmed
    ..transcription-quantitative polymerase chain reactions, were downregulated and upregulated, respectively, in the MSC-transplanted rats; thus suggesting that neural apoptosis was inhibited...
  77. Wang Y, Lin S, Hsieh P, Hung S. Concomitant beige adipocyte differentiation upon induction of mesenchymal stem cells into brown adipocytes. Biochem Biophys Res Commun. 2016;478:689-95 pubmed publisher
    ..Moreover, we found that protein kinase A (PKA) modulators regulated MSC differentiation into brown or beige adipocytes...
  78. Murabayashi D, Mochizuki M, Tamaki Y, Nakahara T. Practical methods for handling human periodontal ligament stem cells in serum-free and serum-containing culture conditions under hypoxia: implications for regenerative medicine. Hum Cell. 2017;30:169-180 pubmed publisher
    ..Our findings indicated that cultivation in serum-free medium does not affect the MSC phenotype or chromosomal stability of PDLSCs...
  79. Park H, Kim Y, Chang J, Yang Y, Oh W, Lee J, et al. Effect of Single and Double Administration of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Following Focal Cerebral Ischemia in Rats. Exp Neurobiol. 2017;26:55-65 pubmed publisher
    ..decrease in infarcted brain volume, as well as increases in neurons and vessels in both single and repeated hUCB-MSC treatments compared to the control group...
  80. Lu J, Wang Q, Huang L, Dong H, Lin L, Tan J. Correlation of CDC42 Activity with Cell Proliferation and Palmitate-Mediated Cell Death in Human Umbilical Cord Wharton's Jelly Derived Mesenchymal Stromal Cells. Stem Cells Dev. 2017;26:1283-1292 pubmed publisher
    ..Cultured human bone marrow, adipose tissue, and hWJ-MSC derived cells had varying pro-inflammatory cytokine secretion levels and cell death rates when treated by palmitate...
  81. Enciso N, Ostronoff L, Mejías G, Leon L, Fermín M, Merino E, et al. Stem cell factor supports migration in canine mesenchymal stem cells. Vet Res Commun. 2018;42:29-38 pubmed publisher
    Adult Mesenchymal Stem Cells (MSC) are cells that can be defined as multipotent cells able to differentiate into diverse lineages, under appropriate conditions...
  82. Walters B, Uynuk Ool T, Rothdiener M, Palm J, Hart M, Stegemann J, et al. Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens. Sci Rep. 2017;7:6640 pubmed publisher
    ..we hypothesized that exogenous forces can be applied for engineering a variety of significantly different MSC shapes...
  83. Liang Y, Wang X, Deng L, Wang L, Wang Y, Huang Y, et al. [Biological characteristics of Microvesicles Derived from Bone Marrow Mesenchymal Stem Cells and Their Capacities Supporting ex vivo Expansion of Hematopoietic Stem Cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017;25:1187-1193 pubmed publisher
    To explore the biological characteristics of microvesicles(MV) derived from bone marrow mesenchymal stem cells (BM-MSC) and their capability supporting ex vivo expansion of hematopoietic stem cells(HSC)...
  84. Hu G, Mai T, Chen C. Visualizing the GPCR Network: Classification and Evolution. Sci Rep. 2017;7:15495 pubmed publisher
    In this study, we delineate an unsupervised clustering algorithm, minimum span clustering (MSC), and apply it to detect G-protein coupled receptor (GPCR) sequences and to study the GPCR network using a base dataset of 2770 GPCR and 652 ..
  85. Zhang Y, Xu C, Gu D, Wu M, Yan B, Xu Z, et al. H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells. Stem Cells. 2017;35:222-235 pubmed publisher
    ..Taken together, our study for the first time showed that H/ACA box snoRNAs are actively involved in MSC proliferation as well as pluripotency control, and we identify SNORA7A as one of the critical snoRNAs that regulate ..
  86. Moya A, Larochette N, Paquet J, Deschepper M, Bensidhoum M, Izzo V, et al. Quiescence Preconditioned Human Multipotent Stromal Cells Adopt a Metabolic Profile Favorable for Enhanced Survival under Ischemia. Stem Cells. 2017;35:181-196 pubmed publisher
    A major impediment to the development of therapies with mesenchymal stem cells/multipotent stromal cells (MSC) is the poor survival and engraftment of MSCs at the site of injury...
  87. Xin H, Wang F, Li Y, Lu Q, Cheung W, Zhang Y, et al. Secondary Release of Exosomes From Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery After Stroke in Rats Treated With Exosomes Harvested From MicroRNA 133b-Overexpressing Multipotent Mesenchymal Strom. Cell Transplant. 2017;26:243-257 pubmed publisher
    ..MCAO) compared with naive MSCs and that exosomes generated from naive MSCs mediate the therapeutic benefits of MSC therapy for stroke...
  88. Lee H, Jo E, Kim S, Yang H, Kim Y, Sung Y, et al. Therapeutic strategies for locally recurrent and metastatic de-differentiated liposarcoma with herpes simplex virus-thymidine kinase-expressing mesenchymal stromal cells. Cytotherapy. 2017;19:1035-1047 pubmed publisher
    ..a new approach to DDLPS therapy with mesenchymal stromal cells expressing herpes simplex virus-thymidine kinase (MSC-TK)...
  89. Kasoju N, Wang H, Zhang B, George J, Gao S, Triffitt J, et al. Transcriptomics of human multipotent mesenchymal stromal cells: Retrospective analysis and future prospects. Biotechnol Adv. 2017;35:407-418 pubmed publisher
    ..In this article, we address the challenges associated with MSC transcriptome studies, the paradoxes observed in published experimental results and the need for careful ..
  90. Augustine S, Avey M, Harrison B, Locke T, Ghannad M, Moher D, et al. Mesenchymal Stromal Cell Therapy in Bronchopulmonary Dysplasia: Systematic Review and Meta-Analysis of Preclinical Studies. Stem Cells Transl Med. 2017;: pubmed publisher
    ..1990 to present) for controlled comparative studies of neonatal animal models that received MSCs or cell free MSC-derived conditioned media (MSC-CM). Lung alveolarization was the primary outcome...
  91. Wang L, Li P, Tian Y, Li Z, Lian C, Ou Q, et al. Human umbilical cord mesenchymal stem cells: subpopulations and their difference in cell biology and effects on retinal degeneration in RCS rats. Curr Mol Med. 2017;: pubmed publisher
    ..To further study the biology and therapeutic effects of these cells, two hUC-MSC subpopulations, termed hUC-MSC1 and hUC-MSC2, were isolated by single-cell cloning method and their therapeutic ..
  92. Ko J, Lee H, Jeong H, Oh J. Ly6Chi monocytes are required for mesenchymal stem/stromal cell-induced immune tolerance in mice with experimental autoimmune uveitis. Biochem Biophys Res Commun. 2017;494:6-12 pubmed publisher
    ..macrophages is increased in the lung by intravenous (IV) administration of mesenchymal stem/stromal cells (MSC) and induces immune tolerance...