MSC

Summary

Gene Symbol: MSC
Description: musculin
Alias: ABF-1, ABF1, MYOR, bHLHa22, musculin, activated B-cell factor 1, homolog of mouse musculin, activated B-cell factor-1, class A basic helix-loop-helix protein 22
Species: human
Products:     MSC

Top Publications

  1. Combs S, Kessel C, Wilkens J, Multhoff G, Schmid T, Vaupel P, et al. Master of Science (MSc) Program in Radiation Biology: An Interdepartmental Course Bridging the Gap between Radiation-Related Preclinical and Clinical Disciplines to Prepare Next-Generation Medical Scientists. Front Oncol. 2017;7:226 pubmed publisher
    ..At the Technical University of Munich (TUM), a full Master of Science (MSc) course in radiation biology has been established...
  2. Uklejewski R, Rogala P, Winiecki M, Tokłowicz R, Ruszkowski P, Wołuń Cholewa M. Biomimetic Multispiked Connecting Ti-Alloy Scaffold Prototype for Entirely-Cementless Resurfacing Arthroplasty Endoprostheses-Exemplary Results of Implantation of the Ca-P Surface-Modified Scaffold Prototypes in Animal Model and Osteoblast Culture Ev. Materials (Basel). 2016;9: pubmed publisher
    ..manufactured, and tested by our research team-the Ti-alloy prototype of the multispiked connecting scaffold (MSC-Scaffold) interfacing the components of resurfacing arthroplasty (RA) endoprostheses with bone...
  3. Giebel B, Kordelas L, Börger V. Clinical potential of mesenchymal stem/stromal cell-derived extracellular vesicles. Stem Cell Investig. 2017;4:84 pubmed publisher
    ..Meanwhile, MSC-EVs have been applied to an increasing amount of different animal models and were tested in a patient suffering ..
  4. Montanari E, Meier R, Mahou R, Seebach J, Wandrey C, Gerber Lemaire S, et al. Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice. Stem Cell Res Ther. 2017;8:199 pubmed publisher
    Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets.
  5. Zhang S, Zeng N, Alowayed N, Singh Y, Cheng A, Lang F, et al. Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells. PLoS ONE. 2017;12:e0183681 pubmed publisher
    ..Cell adhesion and migration are modified by the mesenchymal stem cell (MSC) marker Sushi domain containing 2 (SUSD2), a type I transmembrane protein that participates in the orchestration of ..
  6. Díaz Tocados J, Herencia C, Martinez Moreno J, Montes de Oca A, Rodriguez Ortiz M, Vergara N, et al. Magnesium Chloride promotes Osteogenesis through Notch signaling activation and expansion of Mesenchymal Stem Cells. Sci Rep. 2017;7:7839 pubmed publisher
    Mesenchymal stem cells (MSC) are osteoblasts progenitors and a variety of studies suggest that they may play an important role for the health in the field of bone regeneration...
  7. Liu L, Hua Z, Shen J, Yin Y, Yang J, Cheng K, et al. Comparative Efficacy of Multiple Variables of Mesenchymal Stem Cell Transplantation for the Treatment of Neuropathic Pain in Rats. Mil Med. 2017;182:175-184 pubmed publisher
    ..Mesenchymal stem cell transplantation (MSC) has shown promise as an emerging therapy for neuropathic pain...
  8. Somoza R, Acevedo C, Albornoz F, Luz Crawford P, Carrion F, Young M, et al. TGFβ3 secretion by three-dimensional cultures of human dental apical papilla mesenchymal stem cells. J Tissue Eng Regen Med. 2017;11:1045-1056 pubmed publisher
    ..from dental tissues, such as pulp and periodontal ligament; the dental apical papilla (DAP) is a less-studied MSC source...
  9. Zhu L, Huang X, Yu W, Chen H, Chen Y, Dai Y. Transplantation of adipose tissue-derived stem cell-derived exosomes ameliorates erectile function in diabetic rats. Andrologia. 2017;: pubmed publisher
    ..Exosomes excreted from MSCs have emerged as physiologically relevant and powerful components of the MSC secretome...
  10. Jakobsen K, Grønhøj C, Jensen D, Fischer Nielsen A, Hjuler T, Von Buchwald C. Mesenchymal stem cell therapy for laryngotracheal stenosis: A systematic review of preclinical studies. PLoS ONE. 2017;12:e0185283 pubmed publisher
    ..Mesenchymal stem cells (MSCs) therapy has shown promising results in regenerative medicine. We aimed to systematically review the literature on MSC therapy for stenosis of the conductive airways.

Detail Information

Publications62

  1. Combs S, Kessel C, Wilkens J, Multhoff G, Schmid T, Vaupel P, et al. Master of Science (MSc) Program in Radiation Biology: An Interdepartmental Course Bridging the Gap between Radiation-Related Preclinical and Clinical Disciplines to Prepare Next-Generation Medical Scientists. Front Oncol. 2017;7:226 pubmed publisher
    ..At the Technical University of Munich (TUM), a full Master of Science (MSc) course in radiation biology has been established...
  2. Uklejewski R, Rogala P, Winiecki M, Tokłowicz R, Ruszkowski P, Wołuń Cholewa M. Biomimetic Multispiked Connecting Ti-Alloy Scaffold Prototype for Entirely-Cementless Resurfacing Arthroplasty Endoprostheses-Exemplary Results of Implantation of the Ca-P Surface-Modified Scaffold Prototypes in Animal Model and Osteoblast Culture Ev. Materials (Basel). 2016;9: pubmed publisher
    ..manufactured, and tested by our research team-the Ti-alloy prototype of the multispiked connecting scaffold (MSC-Scaffold) interfacing the components of resurfacing arthroplasty (RA) endoprostheses with bone...
  3. Giebel B, Kordelas L, Börger V. Clinical potential of mesenchymal stem/stromal cell-derived extracellular vesicles. Stem Cell Investig. 2017;4:84 pubmed publisher
    ..Meanwhile, MSC-EVs have been applied to an increasing amount of different animal models and were tested in a patient suffering ..
  4. Montanari E, Meier R, Mahou R, Seebach J, Wandrey C, Gerber Lemaire S, et al. Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice. Stem Cell Res Ther. 2017;8:199 pubmed publisher
    Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets.
  5. Zhang S, Zeng N, Alowayed N, Singh Y, Cheng A, Lang F, et al. Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells. PLoS ONE. 2017;12:e0183681 pubmed publisher
    ..Cell adhesion and migration are modified by the mesenchymal stem cell (MSC) marker Sushi domain containing 2 (SUSD2), a type I transmembrane protein that participates in the orchestration of ..
  6. Díaz Tocados J, Herencia C, Martinez Moreno J, Montes de Oca A, Rodriguez Ortiz M, Vergara N, et al. Magnesium Chloride promotes Osteogenesis through Notch signaling activation and expansion of Mesenchymal Stem Cells. Sci Rep. 2017;7:7839 pubmed publisher
    Mesenchymal stem cells (MSC) are osteoblasts progenitors and a variety of studies suggest that they may play an important role for the health in the field of bone regeneration...
  7. Liu L, Hua Z, Shen J, Yin Y, Yang J, Cheng K, et al. Comparative Efficacy of Multiple Variables of Mesenchymal Stem Cell Transplantation for the Treatment of Neuropathic Pain in Rats. Mil Med. 2017;182:175-184 pubmed publisher
    ..Mesenchymal stem cell transplantation (MSC) has shown promise as an emerging therapy for neuropathic pain...
  8. Somoza R, Acevedo C, Albornoz F, Luz Crawford P, Carrion F, Young M, et al. TGFβ3 secretion by three-dimensional cultures of human dental apical papilla mesenchymal stem cells. J Tissue Eng Regen Med. 2017;11:1045-1056 pubmed publisher
    ..from dental tissues, such as pulp and periodontal ligament; the dental apical papilla (DAP) is a less-studied MSC source...
  9. Zhu L, Huang X, Yu W, Chen H, Chen Y, Dai Y. Transplantation of adipose tissue-derived stem cell-derived exosomes ameliorates erectile function in diabetic rats. Andrologia. 2017;: pubmed publisher
    ..Exosomes excreted from MSCs have emerged as physiologically relevant and powerful components of the MSC secretome...
  10. Jakobsen K, Grønhøj C, Jensen D, Fischer Nielsen A, Hjuler T, Von Buchwald C. Mesenchymal stem cell therapy for laryngotracheal stenosis: A systematic review of preclinical studies. PLoS ONE. 2017;12:e0185283 pubmed publisher
    ..Mesenchymal stem cells (MSCs) therapy has shown promising results in regenerative medicine. We aimed to systematically review the literature on MSC therapy for stenosis of the conductive airways.
  11. Ribeiro A, Ritter T, Griffin M, Ceredig R. Development of a flow cytometry-based potency assay for measuring the in vitro immunomodulatory properties of mesenchymal stromal cells. Immunol Lett. 2016;177:38-46 pubmed publisher
    Human bone marrow-derived mesenchymal stromal/stem cells (MSC) have well-documented modulatory effects on multiple immune cell types...
  12. Lai R, Yeo R, Padmanabhan J, Choo A, de Kleijn D, Lim S. Isolation and Characterization of Exosome from Human Embryonic Stem Cell-Derived C-Myc-Immortalized Mesenchymal Stem Cells. Methods Mol Biol. 2016;1416:477-94 pubmed publisher
    Mesenchymal stem cells (MSC) are currently the cell type of choice in many cell therapy trials...
  13. Kim M, Rhee J, Choi H, Kwon A, Kim J, Lee G, et al. Passage-dependent accumulation of somatic mutations in mesenchymal stromal cells during in vitro culture revealed by whole genome sequencing. Sci Rep. 2017;7:14508 pubmed publisher
    ..Here, we performed whole genome sequencing of two peripheral blood-derived MSC lines (MSC1 and MSC2) at various passages (passage 1 [P1] to P9)...
  14. Chabot D, Tremblay T, Paré I, Bazin R, Loubaki L. Transient warming events occurring after freezing impairs umbilical cord-derived mesenchymal stromal cells functionality. Cytotherapy. 2017;19:978-989 pubmed publisher
    ..While safety of MSC infusion has been demonstrated, the use of cryopreserved MSCs in clinical trials has raised concerns regarding the ..
  15. Neumann A, Lavrentieva A, Heilkenbrinker A, Loenne M, Kasper C. Characterization and Application of a Disposable Rotating Bed Bioreactor for Mesenchymal Stem Cell Expansion. Bioengineering (Basel). 2014;1:231-245 pubmed publisher
    Recruitment of mesenchymal stromal cells (MSC) into the field of tissue engineering is a promising development since these cells can be expanded vivo to clinically relevant numbers and, after expansion, retain their ability to ..
  16. Vanikar A, Trivedi H, Thakkar U. Six years' experience of tolerance induction in renal transplantation using stem cell therapy. Clin Immunol. 2017;: pubmed publisher
    ..results of TI protocol (TIP) using stem cell therapy (SCT) included adipose derived mesenchymal stem cells (AD-MSC) and hematopoietic stem cells (HSC) in 10 living-donor related renal transplantation (LDRT) patients under non-..
  17. Carroll S, Buckley C, Kelly D. Cyclic Tensile Strain Can Play a Role in Directing both Intramembranous and Endochondral Ossification of Mesenchymal Stem Cells. Front Bioeng Biotechnol. 2017;5:73 pubmed publisher
    ..role of cyclic tensile strain (CTS) in regulating the initiation of mesenchymal stem cell/multipotent stromal cell (MSC) differentiation, and specifically their progression along the endochondral pathway...
  18. Maklakova I, Grebnev D, Yastrebov A. [Activation of regeneration of red and white pulp of the spleen after the combined transplantation of HSC and MSCS in terms of exposure to ionizing radiation]. Patol Fiziol Eksp Ter. 2017;61:22-7 pubmed
    ..Conclusion. Studies have shown the effectiveness of combined transplantation MSC and GSK in respect of the main morphometric parameters of the spleen after exposure to ionizing radiation.
  19. Aghajani Nargesi A, Lerman L, Eirin A. Mesenchymal stem cell-derived extracellular vesicles for kidney repair: current status and looming challenges. Stem Cell Res Ther. 2017;8:273 pubmed publisher
    ..b>MSC-derived EVs contain genetic and protein material that upon transferring to recipient cells can activate several ..
  20. Massari M, Rivera R, Voland J, Quong M, Breit T, van Dongen J, et al. Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes. Mol Cell Biol. 1998;18:3130-9 pubmed
    ..ABF-1 represents the first example of a B-cell-restricted bHLH protein, and its expression pattern suggests that ABF-1 may play a role in regulating antigen-dependent B-cell differentiation. ..
  21. Mazor M, Cesaro A, Ali M, Best T, Lespessaille E, Toumi H. Progenitor Cells from Cartilage: Grade Specific Differences in Stem Cell Marker Expression. Int J Mol Sci. 2017;18: pubmed publisher
    Recent research has confirmed the presence of Mesenchymal stem cell (MSC)-like progenitors (MPC) in both normal and osteoarthritic cartilage...
  22. Maj M, Bajek A, Nalejska E, Porowińska D, Kloskowski T, Gackowska L, et al. Influence of Mesenchymal Stem Cells Conditioned Media on Proliferation of Urinary Tract Cancer Cell Lines and Their Sensitivity to Ciprofloxacin. J Cell Biochem. 2017;118:1361-1368 pubmed publisher
    ..involved in chemoresistance acquisition, we further analyzed influence of mesenchymal stem cell conditioned media (MSC-CM) on cancer cells sensitivity to ciprofloxacin, that is considered as potential candidate agent for urinary tract ..
  23. Jezierska Woźniak K, Barczewska M, Habich A, Wojtacha P, Badowska W, Maksymowicz W, et al. The feasibility of the CD271+ and CD271- mesenchymal stromal cell enrichment toward nucleus pulposus-like cells. Folia Histochem Cytobiol. 2017;: pubmed publisher
    ..nerve growth factor receptor) has been identified as a marker of the most homogeneous mesenchymal stem cell (MSC) subset...
  24. Gómez Leduc T, Desancé M, Hervieu M, Legendre F, Ollitrault D, de Vienne C, et al. Hypoxia Is a Critical Parameter for Chondrogenic Differentiation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Type I/III Collagen Sponges. Int J Mol Sci. 2017;18: pubmed publisher
    ..with seven days in normoxia followed by 14 days in hypoxia, since these conditions avoid hypertrophy of hUCB-MSC-derived chondrocytes while maintaining the expression of chondrocyte-specific markers observed in normoxia...
  25. Liu L, Zhang S, Liao W, Farhoodi H, Wong C, Chen C, et al. Mechanoresponsive stem cells to target cancer metastases through biophysical cues. Sci Transl Med. 2017;9: pubmed publisher
    ..Our MRCS uses mechanosensitive promoter-driven mesenchymal stem cell (MSC)-based vectors, which selectively home to and target cancer metastases in response to specific mechanical cues to ..
  26. Goloviznina N, Verghese S, Yoon Y, Taratula O, Marks D, Kurre P. Mesenchymal Stromal Cell-derived Extracellular Vesicles Promote Myeloid-biased Multipotent Hematopoietic Progenitor Expansion via Toll-Like Receptor Engagement. J Biol Chem. 2016;291:24607-24617 pubmed
    ..We systematically characterized EV release by murine stromal cells and demonstrate that MSC-derived EVs prompt a loss of HSPC quiescence with concomitant expansion of murine myeloid progenitors...
  27. Reesink H, Sutton R, Shurer C, Peterson R, Tan J, Su J, et al. Galectin-1 and galectin-3 expression in equine mesenchymal stromal cells (MSCs), synovial fibroblasts and chondrocytes, and the effect of inflammation on MSC motility. Stem Cell Res Ther. 2017;8:243 pubmed publisher
    ..Here, we asked whether equine bone marrow-derived MSCs (BMSCs) express higher levels of galectin-1 and -3 relative to synovial fibroblasts and chondrocytes and if an inflammatory environment affects BMSC galectin expression and motility...
  28. Chao K, Zhang S, Qiu Y, Chen X, Zhang X, Cai C, et al. Human umbilical cord-derived mesenchymal stem cells protect against experimental colitis via CD5(+) B regulatory cells. Stem Cell Res Ther. 2016;7:109 pubmed publisher
    To clarify the effect of human umbilical cord-derived mesenchymal stem cell (hUC-MSCs) treatment on colitis and to explore the role of CD5(+) B cells in MSC therapy.
  29. Liu M, Lei H, Dong P, Fu X, Yang Z, Yang Y, et al. Adipose-Derived Mesenchymal Stem Cells from the Elderly Exhibit Decreased Migration and Differentiation Abilities with Senescent Properties. Cell Transplant. 2017;26:1505-1519 pubmed publisher
    ..hASCs are available from individuals across all age-groups and maintain mesenchymal stem cell (MSC) characteristics...
  30. Qian W, Gong L, Cui X, Zhang Z, Bajpai A, Liu C, et al. Nanotopographic Regulation of Human Mesenchymal Stem Cell Osteogenesis. ACS Appl Mater Interfaces. 2017;: pubmed publisher
    Mesenchymal stem cell (MSC) differentiation can be manipulated by nanotopographic interface providing a unique strategy to engineering stem cell therapy and circumventing complex cellular reprogramming...
  31. Vinod E, Boopalan P, Sathishkumar S. Reserve or Resident Progenitors in Cartilage? Comparative Analysis of Chondrocytes versus Chondroprogenitors and Their Role in Cartilage Repair. Cartilage. 2017;:1947603517736108 pubmed publisher
    ..there is an ill-defined distinction between CPCs and chondrocytes with respect to their cell surface expression (MSC markers and CPC-specific markers) and differentiation potential...
  32. Fernandes Platzgummer A, Carmelo J, da Silva C, Cabral J. Clinical-Grade Manufacturing of Therapeutic Human Mesenchymal Stem/Stromal Cells in Microcarrier-Based Culture Systems. Methods Mol Biol. 2016;1416:375-88 pubmed publisher
    The therapeutic potential of mesenchymal stem/stromal cells (MSC) has triggered the need for high cell doses in a vast number of clinical applications...
  33. Barrera Ramirez J, Lavoie J, Maganti H, Stanford W, Ito C, Sabloff M, et al. Micro-RNA Profiling of Exosomes from Marrow-Derived Mesenchymal Stromal Cells in Patients with Acute Myeloid Leukemia: Implications in Leukemogenesis. Stem Cell Rev. 2017;: pubmed publisher
    ..Known targets of mIRs that were significantly different in AML-derived MSC exosomes compared to controls were identified...
  34. Li Z, Yang A, Yin X, Dong S, Luo F, Dou C, et al. Mesenchymal stem cells promote endothelial progenitor cell migration, vascularization, and bone repair in tissue-engineered constructs via activating CXCR2-Src-PKL/Vav2-Rac1. FASEB J. 2017;: pubmed publisher
    ..Here we analyzed the roles of C-X-C chemokine receptor 2 (CXCR2) and its downstream signal pathways in MSC-induced endothelial progenitor cell (EPC) migration...
  35. Moraghebi R, Kirkeby A, Chaves P, Ronn R, Sitnicka E, Parmar M, et al. Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications. Stem Cell Res Ther. 2017;8:190 pubmed publisher
    ..In this study, we collected amniotic fluid at term using a novel collection system and evaluated amniotic fluid MSC content and their characteristics, including their feasibility to undergo cellular reprogramming...
  36. Kudva A, Luyten F, Patterson J. RGD-functionalized polyethylene glycol hydrogels support proliferation and in vitro chondrogenesis of human periosteum-derived cells. J Biomed Mater Res A. 2018;106:33-42 pubmed publisher
    ..Here, we utilized human periosteum-derived cells (hPDCs), a progenitor cell population with MSC characteristics, paired with protease-degradable, functionalized polyethylene glycol (PEG) hydrogels to create ..
  37. Uynuk Ool T, Rothdiener M, Walters B, Hegemann M, Palm J, Nguyen P, et al. The geometrical shape of mesenchymal stromal cells measured by quantitative shape descriptors is determined by the stiffness of the biomaterial and by cyclic tensile forces. J Tissue Eng Regen Med. 2017;11:3508-3522 pubmed publisher
    Controlling mesenchymal stromal cell (MSC) shape is a novel method for investigating and directing MSC behaviour in vitro...
  38. Costa M, de Soure A, Cabral J, Ferreira F, da Silva C. Hematopoietic niche - exploring biomimetic cues to improve the functionality of Hematopoietic Stem/Progenitor Cells. Biotechnol J. 2017;: pubmed publisher
    ..Particularly, mesenchymal stem/stromal cells (MSC), through their paracrine activity or direct contact with HSPC, are thought to be a relevant niche player, ..
  39. Oliveira M, Saldanha Araujo F, Góes A, Costa F, de Carvalho J. Stem cells in cardiovascular diseases: turning bad days into good ones. Drug Discov Today. 2017;22:1730-1739 pubmed publisher
    ..In the present review, we address strategies under investigation to boost MSC therapy for CVDs...
  40. Moussa L, Pattappa G, Doix B, Benselama S, Demarquay C, Benderitter M, et al. A biomaterial-assisted mesenchymal stromal cell therapy alleviates colonic radiation-induced damage. Biomaterials. 2017;115:40-52 pubmed publisher
    ..In a rat model of radiation-induced severe colonic damage, Ad-MSC + Si-HPMC improve colonic epithelial structure and hyperpermeability compared with Ad-MSCs injected intravenously ..
  41. Bajetto A, Pattarozzi A, Corsaro A, Barbieri F, Daga A, Bosio A, et al. Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors. Front Cell Neurosci. 2017;11:312 pubmed publisher
    ..Different studies reported either MSC anti-tumor activity or their support to tumor growth...
  42. Najar M, Dollé L, Crompot E, Verhulst S, van Grunsven L, Busser H, et al. Isolation and characterization of mesenchymal stromal cells based on aldehyde dehydrogenase activity. Tissue Eng Part C Methods. 2017;: pubmed publisher
    ..Both BM-MSC populations look to significantly differ in terms of biological responses and functionalities...
  43. Vulcano F, Milazzo L, Ciccarelli C, Eramo A, Sette G, Mauro A, et al. Wharton's jelly mesenchymal stromal cells have contrasting effects on proliferation and phenotype of cancer stem cells from different subtypes of lung cancer. Exp Cell Res. 2016;345:190-8 pubmed publisher
    Studies on the role of multipotent mesenchymal stromal cells (MSC) on tumor growth have reported both a tumor promoting and a suppressive effect...
  44. Lam P, Wang K, Lo A, Tong C, Ching D, Wong K, et al. Interactome and reciprocal activation of pathways in topical mesenchymal stem cells and the recipient cerebral cortex following traumatic brain injury. Sci Rep. 2017;7:5017 pubmed publisher
    ..Artn, Ptn); cytokine (IL3); cell cycle (Hdac4); and notch signaling (Hes1) were up-regulated three days after MSC transplant...
  45. Daltro P, Barreto B, Silva P, Neto P, Sousa Filho P, Santana Neta D, et al. Therapy with mesenchymal stromal cells or conditioned medium reverse cardiac alterations in a high-fat diet-induced obesity model. Cytotherapy. 2017;19:1176-1188 pubmed publisher
    ..This functional improvement correlated with normalization of GATA4 gene expression in the hearts of MSC- or CM-treated mice...
  46. Maji S, Yan I, Parasramka M, Mohankumar S, Matsuda A, Patel T. In vitro toxicology studies of extracellular vesicles. J Appl Toxicol. 2017;37:310-318 pubmed publisher
    ..EVs were obtained from mesenchymal stem cells (MSC-EV) or from bovine milk (BM-EV) by differential ultracentrifugation, and quantitated using nanoparticle tracking ..
  47. Boulos S, Park M, Zeibak M, Foo S, Jeon Y, Kim Y, et al. Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma. Oncotarget. 2017;8:65186-65198 pubmed publisher
    ..phosphorylated lysyl-tRNA synthetase (P-s207 LysRS) is released from the cytoplasmic multi-tRNA synthetase complex (MSC) into the nucleus, where it activates the transcription factor MITF in stimulated cultured mast cells and ..
  48. Corradetti B, Taraballi F, Martinez J, Minardi S, Basu N, Bauza G, et al. Hyaluronic acid coatings as a simple and efficient approach to improve MSC homing toward the site of inflammation. Sci Rep. 2017;7:7991 pubmed publisher
    ..Mesenchymal stem cells (MSC) are currently employed for the treatment of inflammatory-based diseases, due to their powerful immunosoppressive ..
  49. Xu R, Zhao H, Muhammad H, Dong M, Besenbacher F, Chen M. Dual-delivery of FGF-2/CTGF from Silk Fibroin/PLCL-PEO Coaxial Fibers Enhances MSC Proliferation and Fibrogenesis. Sci Rep. 2017;7:8509 pubmed publisher
    ....
  50. Petecchia L, Usai C, Vassalli M, Gavazzo P. Biophysical characterization of nanostructured TiO2 as a good substrate for hBM-MSC adhesion, growth and differentiation. Exp Cell Res. 2017;358:111-119 pubmed publisher
    Mesenchymal stem cells from human bone marrow (hBM-MSC) are widely utilized for clinical applications involving bone healing...
  51. Ishiy F, Fanganiello R, Kobayashi G, Kague E, Kuriki P, Passos Bueno M. CD105 is regulated by hsa-miR-1287 and its expression is inversely correlated with osteopotential in SHED. Bone. 2018;106:112-120 pubmed publisher
    ..accurate understanding of the molecular mechanisms and signaling pathways underpinning human mesenchymal stem cell (MSC) plasticity and differentiation properties is pivotal for accomplishing solid and diligent translation of MSC-based ..
  52. Martínez V, Ontoria Oviedo I, Ricardo C, Harding S, Sacedon R, Varas A, et al. Overexpression of hypoxia-inducible factor 1 alpha improves immunomodulation by dental mesenchymal stem cells. Stem Cell Res Ther. 2017;8:208 pubmed publisher
    ..Hypoxia-preconditioning and hypoxia-inducible factor 1 (HIF-1) alpha overexpression significantly improves MSC therapeutics, but the mechanisms involved are not fully understood...
  53. Moreira A, Kahlenberg S, Hornsby P. Therapeutic potential of mesenchymal stem cells for diabetes. J Mol Endocrinol. 2017;59:R109-R120 pubmed publisher
    ..This review will summarize the role of MSCs on tissue repair, provide emerging strategies to improve MSC function and describe how these processes translate to clinical treatments for diabetes.
  54. Yang H, Zheng Y, Zhang Y, Cao Z, Jiang Y. Mesenchymal stem cells derived from multiple myeloma patients protect against chemotherapy through autophagy-dependent activation of NF-κB signaling. Leuk Res. 2017;60:82-88 pubmed publisher
    ..Inhibition of NF-κB signaling reversed the protective effects of MM-MSC on MM cells...
  55. Buckley D, Fraser A, Huang G, Jiang X. Recovery Optimization and Survival of the Human Norovirus Surrogates Feline Calicivirus and Murine Norovirus on Carpet. Appl Environ Microbiol. 2017;83: pubmed publisher
    ..potential and absorption capacity of wool and nylon carpet fibers, we then developed a minispin column elution (MSC) method, and lastly we characterized the survival of HuNoV surrogates, feline calicivirus (FCV) and murine ..
  56. Hervé M, Ibrahim E. MicroRNA screening identifies a link between NOVA1 expression and a low level of IKAP in familial dysautonomia. Dis Model Mech. 2016;9:899-909 pubmed publisher
    ..and reverse transcription coupled to quantitative PCR (RT-qPCR) on two biological replicate series of hOE-MSC cultures from healthy controls and FD patients...
  57. Tomasello L, Mauceri R, Coppola A, Pitrone M, Pizzo G, Campisi G, et al. Mesenchymal stem cells derived from inflamed dental pulpal and gingival tissue: a potential application for bone formation. Stem Cell Res Ther. 2017;8:179 pubmed publisher
    ..The effects of proinflammatory cytokines on mesenchymal stem cell (MSC) proliferation and differentiation potential were investigated...
  58. Li Z, Xu X, Wang W, Kratz K, Sun X, Zou J, et al. Modulation of the mesenchymal stem cell migration capacity via preconditioning with topographic microstructure. Clin Hemorheol Microcirc. 2017;67:267-278 pubmed publisher
    ..created on polystyrene (PS) culture vessel surfaces as a feasible physical preconditioning strategy to modulate MSC migration...
  59. Smith C, Board T, Rooney P, Eagle M, Richardson S, Hoyland J. Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone. PLoS ONE. 2017;12:e0177416 pubmed publisher
    ..Such scaffolds should retain their innate biological and biomechanical capacity and support mesenchymal stem cell (MSC) osteogenic differentiation...
  60. Gazdic M, Arsenijević A, Markovic B, Volarevic A, Dimova I, Djonov V, et al. Mesenchymal Stem Cell-Dependent Modulation of Liver Diseases. Int J Biol Sci. 2017;13:1109-1117 pubmed publisher
    ..In this review, we highlight the current findings on the MSC-based modulation of liver inflammation and fibrosis, and the possible use of MSCs in the therapy of immune-mediated ..
  61. Zhou J, Wei F, Ma Y. Inhibiting PPARγ by erythropoietin while upregulating TAZ by IGF1 synergistically promote osteogenic differentiation of mesenchymal stem cells. Biochem Biophys Res Commun. 2016;478:349-355 pubmed publisher
    Erythropoietin (EPO) is reported to promote osteogenesis and inhibit adipogenesis of mesenchymal stem cells (MSC) through inhibiting PPARγ, while insulin-like growth factor 1 (IGF1) is able to enhance osteogenesis via upregulating ..
  62. Rashedi I, Talele N, Wang X, Hinz B, Radisic M, Keating A. Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells. PLoS ONE. 2017;12:e0187348 pubmed publisher
    ..in myocardial function by MSCs after acquisition of a partial cardiac cell-like phenotype is not due to enhanced MSC contractility...