IMPACT

Summary

Gene Symbol: IMPACT
Description: impact RWD domain protein
Alias: RWDD5, protein IMPACT, Impact homolog, RWD domain containing 5, imprinted and ancient gene protein homolog
Species: human
Products:     IMPACT

Top Publications

  1. Park W, Zwink N, Rösch W, Schmiedeke E, Stein R, Schmidt D, et al. Sexual function in adult patients with classic bladder exstrophy: A multicenter study. J Pediatr Urol. 2015;11:125.e1-6 pubmed publisher
    ..a spectrum of congenital anomalies that represents the severe end of urorectal malformations, and has a profound impact on continence as well as sexual and renal functions...
  2. Morris J, Twizeyemariya A, Grimmer K. What is the current evidence of the impact on quality of life whilst waiting for management/treatment of orthopaedic/musculoskeletal complaints? A systematic scoping review. Qual Life Res. 2018;: pubmed publisher
    ..The scoping search yielded 142 articles, of which 18 reported on impact on QoL. These studies reported only on patients waiting for hip and/or knee replacement surgery...
  3. Acarturk C, Konuk E, Cetinkaya M, Senay I, Sijbrandij M, Cuijpers P, et al. EMDR for Syrian refugees with posttraumatic stress disorder symptoms: results of a pilot randomized controlled trial. Eur J Psychotraumatol. 2015;6:27414 pubmed publisher
    ..The main outcome measures were Impact of Event Scale-Revised (IES-R) and Beck Depression Inventory (BDI-II) at posttreatment and 4-week follow-up...
  4. Javadi Khederi S, Khanjani M, Gholami M, Panzarino O, De Lillo E. Influence of the erineum strain of Colomerus vitis (Acari: Eriophyidae) on grape (Vitis vinifera) defense mechanisms. Exp Appl Acarol. 2018;75:1-24 pubmed publisher
    ..In order to evaluate the impact of GEM on grape and its defense mechanisms against the mite, an exploratory study was carried out on 19 cultivars (..
  5. Benelli G. Mode of action of nanoparticles against insects. Environ Sci Pollut Res Int. 2018;: pubmed publisher
    ..Both silver and graphene oxide nanoparticles have a significant impact on insect antioxidant and detoxifying enzymes, leading to oxidative stress and cell death...
  6. Liu Y, Jolly C, Braun S, Janssen T, Scherer E, Steinhoff J, et al. Effects of a dexamethasone-releasing implant on cochleae: A functional, morphological and pharmacokinetic study. Hear Res. 2015;327:89-101 pubmed publisher
    This study evaluated the impact of a dexamethasone-releasing silicone implant on hearing function preservation, cochlear morphology and perilymph pharmacokinetics after cochlear implantation...
  7. Chauvet S, Bridoux F, Ecotière L, Javaugue V, Sirac C, Arnulf B, et al. Kidney diseases associated with monoclonal immunoglobulin M-secreting B-cell lymphoproliferative disorders: a case series of 35 patients. Am J Kidney Dis. 2015;66:756-67 pubmed publisher
    ..Retrospective study; insufficient population to establish the impact of chemotherapy...
  8. Blake D. Eimeria genomics: Where are we now and where are we going?. Vet Parasitol. 2015;212:68-74 pubmed publisher
    ..been slower for parasites of animals which lack zoonotic potential, but the deficit is now being redressed with impact likely in the areas of drug and vaccine development, molecular diagnostics and population biology...
  9. Mizuma A, Nagata E, Yasuda T, Kouchi M, Nakayama T, Honma K, et al. Botulinum toxin A is effective to treat tension-type headache caused by hemifacial spasm. J Clin Neurosci. 2017;44:284-288 pubmed publisher
    ..Numerical Rating Scale (NRS) and Headache Impact Test-6 (HIT-6) scores for headache severity were compared between the 6-week baseline before BoNT/A therapy and 6-..
  10. Mortuaire G, Leroy X, Gengler I, Chevalier D, Prin L, Picry A. Histopathological classification of refractory chronic rhinosinusitis with nasal polyps. Histol Histopathol. 2015;30:1447-54 pubmed publisher
    ..Further studies concerning mucosal remodelling and outcome assessment after sinus surgery are required to evaluate the impact of our classification on a daily basis.

Detail Information

Publications124 found, 100 shown here

  1. Park W, Zwink N, Rösch W, Schmiedeke E, Stein R, Schmidt D, et al. Sexual function in adult patients with classic bladder exstrophy: A multicenter study. J Pediatr Urol. 2015;11:125.e1-6 pubmed publisher
    ..a spectrum of congenital anomalies that represents the severe end of urorectal malformations, and has a profound impact on continence as well as sexual and renal functions...
  2. Morris J, Twizeyemariya A, Grimmer K. What is the current evidence of the impact on quality of life whilst waiting for management/treatment of orthopaedic/musculoskeletal complaints? A systematic scoping review. Qual Life Res. 2018;: pubmed publisher
    ..The scoping search yielded 142 articles, of which 18 reported on impact on QoL. These studies reported only on patients waiting for hip and/or knee replacement surgery...
  3. Acarturk C, Konuk E, Cetinkaya M, Senay I, Sijbrandij M, Cuijpers P, et al. EMDR for Syrian refugees with posttraumatic stress disorder symptoms: results of a pilot randomized controlled trial. Eur J Psychotraumatol. 2015;6:27414 pubmed publisher
    ..The main outcome measures were Impact of Event Scale-Revised (IES-R) and Beck Depression Inventory (BDI-II) at posttreatment and 4-week follow-up...
  4. Javadi Khederi S, Khanjani M, Gholami M, Panzarino O, De Lillo E. Influence of the erineum strain of Colomerus vitis (Acari: Eriophyidae) on grape (Vitis vinifera) defense mechanisms. Exp Appl Acarol. 2018;75:1-24 pubmed publisher
    ..In order to evaluate the impact of GEM on grape and its defense mechanisms against the mite, an exploratory study was carried out on 19 cultivars (..
  5. Benelli G. Mode of action of nanoparticles against insects. Environ Sci Pollut Res Int. 2018;: pubmed publisher
    ..Both silver and graphene oxide nanoparticles have a significant impact on insect antioxidant and detoxifying enzymes, leading to oxidative stress and cell death...
  6. Liu Y, Jolly C, Braun S, Janssen T, Scherer E, Steinhoff J, et al. Effects of a dexamethasone-releasing implant on cochleae: A functional, morphological and pharmacokinetic study. Hear Res. 2015;327:89-101 pubmed publisher
    This study evaluated the impact of a dexamethasone-releasing silicone implant on hearing function preservation, cochlear morphology and perilymph pharmacokinetics after cochlear implantation...
  7. Chauvet S, Bridoux F, Ecotière L, Javaugue V, Sirac C, Arnulf B, et al. Kidney diseases associated with monoclonal immunoglobulin M-secreting B-cell lymphoproliferative disorders: a case series of 35 patients. Am J Kidney Dis. 2015;66:756-67 pubmed publisher
    ..Retrospective study; insufficient population to establish the impact of chemotherapy...
  8. Blake D. Eimeria genomics: Where are we now and where are we going?. Vet Parasitol. 2015;212:68-74 pubmed publisher
    ..been slower for parasites of animals which lack zoonotic potential, but the deficit is now being redressed with impact likely in the areas of drug and vaccine development, molecular diagnostics and population biology...
  9. Mizuma A, Nagata E, Yasuda T, Kouchi M, Nakayama T, Honma K, et al. Botulinum toxin A is effective to treat tension-type headache caused by hemifacial spasm. J Clin Neurosci. 2017;44:284-288 pubmed publisher
    ..Numerical Rating Scale (NRS) and Headache Impact Test-6 (HIT-6) scores for headache severity were compared between the 6-week baseline before BoNT/A therapy and 6-..
  10. Mortuaire G, Leroy X, Gengler I, Chevalier D, Prin L, Picry A. Histopathological classification of refractory chronic rhinosinusitis with nasal polyps. Histol Histopathol. 2015;30:1447-54 pubmed publisher
    ..Further studies concerning mucosal remodelling and outcome assessment after sinus surgery are required to evaluate the impact of our classification on a daily basis.
  11. Fleury Y, Arroyo D, Couchepin C, Robert Ebadi H, Righini M, Lobrinus J, et al. Impact of intravascular thrombosis on failure of radial arterial catheters in critically ill patients: a nested case-control study. Intensive Care Med. 2018;: pubmed publisher
    ..Most failing radial arterial catheters had no luminal obstruction, but were associated with an intravascular thrombosis. Among predictive factors, arterial blood sampling frequency is the most susceptible to intervention. ..
  12. Di Cristofaro J, Reynaud Gaubert M, Carlini F, Roubertoux P, Loundou A, Basire A, et al. HLA-G*01:04∼UTR3 Recipient Correlates With Lower Survival and Higher Frequency of Chronic Rejection After Lung Transplantation. Am J Transplant. 2015;15:2413-20 pubmed publisher
    ..The aim of this retrospective study was to determine the impact of HLA-G alleles and UTR polymorphism from LTx recipients on anti-HLA allo-immunization risk, overall survival and ..
  13. Cieniewicz B, Dong Q, Li G, Forrest J, Mounce B, Tarakanova V, et al. Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture. J Virol. 2015;89:6562-74 pubmed publisher
    ..The impact of the inflammasome response on gammaherpesvirus replication and latency in vivo is not known...
  14. Card R, Mafura M, Hunt T, Kirchner M, Weile J, Rashid M, et al. Impact of Ciprofloxacin and Clindamycin Administration on Gram-Negative Bacteria Isolated from Healthy Volunteers and Characterization of the Resistance Genes They Harbor. Antimicrob Agents Chemother. 2015;59:4410-6 pubmed publisher
    The aim of this study was to assess the impact of ciprofloxacin, clindamycin, and placebo administration on culturable Gram-negative isolates and the antibiotic resistance genes they harbor...
  15. House L, Morris R, Barnes T, Lantier L, Cyphert T, McGuinness O, et al. Tissue inflammation and nitric oxide-mediated alterations in cardiovascular function are major determinants of endotoxin-induced insulin resistance. Cardiovasc Diabetol. 2015;14:56 pubmed publisher
    ..The impact of NO donor infusion on insulin-stimulated whole-body and muscle glucose uptake (hyperinsulinemic-euglycemic ..
  16. Reddy V, Reddy G. Role of crystallins in diabetic complications. Biochim Biophys Acta. 2016;1860:269-77 pubmed publisher
    ..Therefore, this review highlights the current data on the impact of chronic hyperglycemia on expression, distribution, glycation, phosphorylation, chaperone-like function and, ..
  17. Bertrand L, Toborek M. Dysregulation of Endoplasmic Reticulum Stress and Autophagic Responses by the Antiretroviral Drug Efavirenz. Mol Pharmacol. 2015;88:304-15 pubmed publisher
    ..virus (HIV) treatment have toxic effects that result in various cellular and tissue pathologies; however, their impact on the cells composing the blood-brain barrier is poorly understood...
  18. Cicero A, Benelli M, Brancaleoni M, Dainelli G, Merlini D, Negri R. Middle and Long-Term Impact of a Very Low-Carbohydrate Ketogenic Diet on Cardiometabolic Factors: A Multi-Center, Cross-Sectional, Clinical Study. High Blood Press Cardiovasc Prev. 2015;22:389-94 pubmed publisher
  19. Lone A, Atci E, Renslow R, Beyenal H, NOH S, Fransson B, et al. Colonization of epidermal tissue by Staphylococcus aureus produces localized hypoxia and stimulates secretion of antioxidant and caspase-14 proteins. Infect Immun. 2015;83:3026-34 pubmed publisher
    ..These results are consistent with a localized biological impact from S. aureus in response to colonization of the skin surface.
  20. Muser D, Santangeli P, Castro S, Liang J, Enríquez A, Werner T, et al. Prognostic role of serial quantitative evaluation of 18F-fluorodeoxyglucose uptake by PET/CT in patients with cardiac sarcoidosis presenting with ventricular tachycardia. Eur J Nucl Med Mol Imaging. 2018;: pubmed publisher
    ..We sought to investigate the clinical impact of serial quantitative FDG uptake analysis in patients with CS presenting with ventricular tachycardia (VT) ..
  21. Bryk A, Wypasek E, Awsiuk M, Maj D, Undas A. Warfarin Metabolites in Patients Following Cardiac Valve Implantation: A Contribution of Clinical and Genetic Factors. Cardiovasc Drugs Ther. 2015;29:257-64 pubmed publisher
    ..R-warfarin is metabolized by multiple cytochromes P450. We sought to assess the impact of clinical and genetic factors on circulating warfarin metabolites following valve implantation...
  22. Dagnachew S, Bezie M, Terefe G, Abebe G, Barry J, Goddeeris B. Comparative clinico-haematological analysis in young Zebu cattle experimentally infected with Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia. Acta Vet Scand. 2015;57:24 pubmed publisher
    ..the Northwest region, is affected by both tsetse and non-tsetse fly transmitted trypanosomosis, with significant impact on livestock productivity...
  23. Feng X, Szulzewsky F, Yerevanian A, Chen Z, Heinzmann D, Rasmussen R, et al. Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis. Oncotarget. 2015;6:15077-94 pubmed
    ..Loss of Cx3cr1 in microglia in a monocyte-free environment had no impact on tumor growth and did not alter microglial migration...
  24. Wang L, Gao X, Li J, Yu H, Su H, Liu L, et al. Effects of preemptive analgesia with parecoxib sodium on haemodynamics and plasma stress hormones in surgical patients with thyroid carcinoma. Asian Pac J Cancer Prev. 2015;16:3977-80 pubmed
    ..analgesia before anesthesia and after surgery can effectively reduce the levels of plasma stress hormones and improve analgesic effects in surgical patients with thyroid carcinoma, and without conspicuous impact on haemodynamics.
  25. Farsalinos K, Voudris V, Poulas K. Are metals emitted from electronic cigarettes a reason for health concern? A risk-assessment analysis of currently available literature. Int J Environ Res Public Health. 2015;12:5215-32 pubmed publisher
    Studies have found that metals are emitted to the electronic cigarette (EC) aerosol. However, the potential health impact of exposure to such metals has not been adequately defined...
  26. Peng C, Uygun S, Shiu S, Last R. The Impact of the Branched-Chain Ketoacid Dehydrogenase Complex on Amino Acid Homeostasis in Arabidopsis. Plant Physiol. 2015;169:1807-20 pubmed publisher
    ..Together, these results demonstrate the consequences of blocking BCAA catabolism during both normal growth conditions and under energy-limited conditions. ..
  27. Rochette P, Bourget A, Sanabria Solano C, Lahmidi S, Lavallée G, Pearson A. Mutation of UL24 impedes the dissemination of acute herpes simplex virus 1 infection from the cornea to neurons of trigeminal ganglia. J Gen Virol. 2015;96:2794-805 pubmed publisher
    ..Herein, we investigated how UL24 contributed to acute infection of TG. Our results comparing the impact of UL24 on viral titres in eye tissue versus in tear films did not reveal a general defect in virus release from ..
  28. Bartoszek G, Fischer U, Grill E, Müller M, Nadolny S, Meyer G. Impact of joint contracture on older persons in a geriatric setting: A cross-sectional study. Z Gerontol Geriatr. 2015;48:625-32 pubmed publisher
    ..phenomenon in older persons and are assessed by measuring the range of motion; however, little is known about the impact of joint contractures on activities of daily living (ADL)...
  29. Otabil K, Tenkorang S. Filarial hydrocele: a neglected condition of a neglected tropical disease. J Infect Dev Ctries. 2015;9:456-62 pubmed publisher
    ..This review highlights the socio-economic impact of the disease, the role of the immune system in hydrocele development, current diagnostic approaches, and the ..
  30. Kuo P, Chen S, Shyr Y, Kuo Y, Lee R, Wang S. Hepatoid carcinoma of the pancreas. World J Surg Oncol. 2015;13:185 pubmed publisher
    ..0 months. Unresectability, hepatic, and lymph node metastases are associated with negative impact on survival outcome...
  31. Cao L, Wang S, Zhang Y, Wong K, Nakatsu G, Wang X, et al. Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A. Oncogene. 2018;: pubmed publisher
    ..Here we elucidated the functional significance, molecular mechanisms and clinical impact of ZNF471 in gastric cancer...
  32. Abdelhalim A, Elshal A, Elsawy A, Helmy T, Orban H, Dawaba M, et al. Bricker Conduit for Pediatric Urinary Diversion--Should we Still Offer It?. J Urol. 2015;194:1414-9 pubmed publisher
    ..The Bricker conduit does not seem to halt renal deterioration in children. Negative impact on growth and quality of life, and the anticipated rate of complications are significant limitations of the ..
  33. Jia H, Jiao Y, Wang G, Li Y, Jia H, Wu H, et al. Genetic diversity of male and female Chinese bayberry (Myrica rubra) populations and identification of sex-associated markers. BMC Genomics. 2015;16:394 pubmed publisher
    ..Knowledge of males may have a major impact on conservation and genetic improvement as well as on breeding...
  34. Jost P, Svobodová H, Stetina R. Induction and repair of DNA cross-links induced by sulfur mustard in the A-549 cell line followed by a comet assay. Chem Biol Interact. 2015;237:31-7 pubmed publisher
    Sulfur mustard is a highly toxic chemical warfare agent with devastating impact on intoxicated tissues. DNA cross-links are probably the most toxic DNA lesions induced in the cell by sulfur mustard...
  35. Li Y, Melnikov A, Levenson V, Guerra E, Simeone P, Alberti S, et al. A seven-gene CpG-island methylation panel predicts breast cancer progression. BMC Cancer. 2015;15:417 pubmed publisher
    ..Our findings identify CpG-island methylation profiles with deep impact on clinical outcome, paving the way for use as novel prognostic assays in clinical settings.
  36. Yamasaki S, Chihara D, Kim S, Izutsu K, Iwato K, Fukuda T, et al. Impact of hematopoietic stem cell transplantation in patients with relapsed or refractory mantle cell lymphoma. Ann Hematol. 2018;: pubmed publisher
    ..0054) were risk factors after allogeneic HCT. Strategies that carefully select R/R MCL patients for autologous HCT may allow the identification of individuals suitable for allogeneic HCT. ..
  37. Tanguy M, Kouatchet A, Tanguy B, Pichard E, Fanello S, Joly Guillou M. Management of an Acinetobacter baumannii outbreak in an intensive care unit. Med Mal Infect. 2017;47:409-414 pubmed publisher
    ..baumannii outbreak and to evaluate the control measures taken. The secondary objective was to evaluate the impact of the electronic alert system on the incidence of multidrug resistance to antibiotics...
  38. Goldmuntz E, Cassedy A, Mercer Rosa L, Fogel M, Paridon S, Marino B. Exercise Performance and 22q11.2 Deletion Status Affect Quality of Life in Tetralogy of Fallot. J Pediatr. 2017;189:162-168 pubmed publisher
    ..The patients with a 22q11.2 deletion and their parents reported lower total and Disease Impact scores compared with the group without a deletion on the Pediatric Cardiac Quality of Life Inventory...
  39. de Aguiar Cipriano P, Ekici L, Barnes R, Gomes C, Talcott S. Pre-heating and polyphenol oxidase inhibition impact on extraction of purple sweet potato anthocyanins. Food Chem. 2015;180:227-34 pubmed publisher
    ..Minimizing the impact of PPO with heat was critical to the extraction and recovery of PSP anthocyanins, suitable for food use.
  40. López Vicario C, Rius B, Alcaraz Quiles J, García Alonso V, Lopategi A, Titos E, et al. Pro-resolving mediators produced from EPA and DHA: Overview of the pathways involved and their mechanisms in metabolic syndrome and related liver diseases. Eur J Pharmacol. 2016;785:133-143 pubmed publisher
    ..inflammatory status present in adipose tissue of obese individuals and describe the potential therapeutic impact of these bioactive lipid autacoids on the prevention of hepatic co-morbidities associated with obesity and the ..
  41. Sah S, Varshney U. Impact of Mutating the Key Residues of a Bifunctional 5,10-Methylenetetrahydrofolate Dehydrogenase-Cyclohydrolase from Escherichia coli on Its Activities. Biochemistry. 2015;54:3504-13 pubmed publisher
    ..coli FolD. ..
  42. Ranji P, Akbarzadeh A, Rahmati Yamchi M. Associations of Probiotics with Vitamin D and Leptin Receptors and their Effects on Colon Cancer. Asian Pac J Cancer Prev. 2015;16:3621-7 pubmed
    ..Recent studies have suggested that microbial and environmental factors including diet and lifestyle can impact on colon cancer development...
  43. Fleischmann I, Warschkow R, Beutner U, Marti L, Schmied B, Steffen T. Improved survival after retrieval of 12 or more regional lymph nodes in appendiceal cancer. Eur J Surg Oncol. 2017;43:1876-1885 pubmed publisher
    ..The impact of the number of RLN removed on OS and CSS was assessed using joinpoint regression, Cox regression, and propensity ..
  44. Casini A, Sokollik C, Lukowski S, Lurz E, Rieubland C, de Moerloose P, et al. Hypofibrinogenemia and liver disease: a new case of Aguadilla fibrinogen and review of the literature. Haemophilia. 2015;21:820-7 pubmed publisher
    ..Angers showed a novel helical structure in place of hole 'a' on the outer edge of γD likely to have a negative impact on fibrinogen assembly and secretion...
  45. Russell C, Young I, Leung V, Morris K. Healthcare workers' decision-making about transmission-based infection control precautions is improved by a guidance summary card. J Hosp Infect. 2015;90:235-9 pubmed publisher
    ..To evaluate the impact of a TBP guidance summary card on HCWs' decision-making about the appropriate implementation of TBPs...
  46. Hung C, Chen W, Hsu C, Aljuffali I, Shih H, Fang J. Cutaneous penetration of soft nanoparticles via photodamaged skin: Lipid-based and polymer-based nanocarriers for drug delivery. Eur J Pharm Biopharm. 2015;94:94-105 pubmed publisher
    Photoaging is recognized as the factor damaging skin-barrier function. The aim of this study was to examine the impact of ultraviolet (UV) irradiation on the cutaneous penetration of soft nanoparticles, including nanostructured lipid ..
  47. Erel R, Yermiyahu U, Ben Gal A, Dag A, Shapira O, Schwartz A. Modification of non-stomatal limitation and photoprotection due to K and Na nutrition of olive trees. J Plant Physiol. 2015;177:1-10 pubmed publisher
    ..The overall impact of K and Na nutrition plays down any indirect effect on stomatal limitation and rather demonstrates the centrality ..
  48. Fukuyama T, Takahashi Y, Kubota Y, Mogami Y, Imai K, Kondo Y, et al. Semi-quantitative analyses of antibodies to N-methyl-d-aspartate type glutamate receptor subunits (GluN2B & GluN1) in the clinical course of Rasmussen syndrome. Epilepsy Res. 2015;113:34-43 pubmed publisher
    ..These antibodies may impact the pathophysiology of RS in the most active stage, and could be a marker for active inflammation in the clinical ..
  49. Antosh D, High R, Brown H, Oliphant S, Abed H, Philip N, et al. Feasibility of prophylactic salpingectomy during vaginal hysterectomy. Am J Obstet Gynecol. 2017;217:605.e1-605.e5 pubmed publisher
    ..objectives included identification of factors associated with unsuccessful salpingectomy and assessment of its impact on operating time, blood loss, surgical complications, and menopausal symptoms...
  50. Gupta I, Roy A. Economic Studies on Non-Communicable Diseases and Injuries in India: A Systematic Review. Appl Health Econ Health Policy. 2018;: pubmed publisher
    ..Our objective was to understand the extent to which economic analysis has been used in India to (1) analyze the impact of NCDI and (2) evaluate prevention and treatment interventions...
  51. Bonneau C, Hequet D, Estevez J, Pouget N, Rouzier R. Impact of axillary dissection in women with invasive breast cancer who do not fit the Z0011 ACOSOG trial because of three or more metastatic sentinel lymph nodes. Eur J Surg Oncol. 2015;41:998-1004 pubmed publisher
    ..A subgroup of patients with 3 MLN had a better SS with ALND, possibly due to an under-staging of the SLNB-alone group. ..
  52. Fan J, Semenzin E, Meng W, Giubilato E, Zhang Y, Critto A, et al. Ecological status classification of the Taizi River Basin, China: a comparison of integrated risk assessment approaches. Environ Sci Pollut Res Int. 2015;22:14738-54 pubmed publisher
    ..2012) indicates that the selection of indicators and integrating methodologies can have a relevant impact on the classification of the ecological status...
  53. Mague S, Port R, McMullen M, Carlson G, Turner J. Mouse model of OPRM1 (A118G) polymorphism has altered hippocampal function. Neuropharmacology. 2015;97:426-35 pubmed publisher
    ..In order to investigate the impact of this SNP on circuit function, we used voltage-sensitive dye imaging in hippocampal slices and in vivo ..
  54. Tillault A, Fourmann J, Loegler C, Wieden H, Kothe U, Charpentier B. Contribution of two conserved histidines to the dual activity of archaeal RNA guide-dependent and -independent pseudouridine synthase Cbf5. RNA. 2015;21:1233-9 pubmed publisher
    ..The impact of the mutations was analyzed for unguided modifications U(55) in tRNA and U2603 in 23S rRNA, and for activity of ..
  55. Juenemann M, Braun T, Doenges S, Nedelmann M, Mueller C, Bachmann G, et al. Aquaporin-4 autoantibodies increase vasogenic edema formation and infarct size in a rat stroke model. BMC Immunol. 2015;16:30 pubmed publisher
    ..9.2 ms ± 5.2 ms; p < 0.05). These results support the functional impact of NMO-antibodies and also offer an in-vivo-applicable animal model to investigate the properties of AQP4 in ..
  56. Schwartz M, Peshkin B, Isaacs C, Willey S, Valdimarsdottir H, Nusbaum R, et al. Randomized trial of proactive rapid genetic counseling versus usual care for newly diagnosed breast cancer patients. Breast Cancer Res Treat. 2018;: pubmed publisher
    ..genetic counseling participation, this did not result in increased rates of pre-surgical genetic testing or impact surgical decisions...
  57. Woodard L, Adepoju O, Amspoker A, Virani S, Ramsey D, Petersen L, et al. Impact of Patient-Centered Medical Home Implementation on Diabetes Control in the Veterans Health Administration. J Gen Intern Med. 2018;: pubmed publisher
    ..dissemination across primary care, the Veterans Health Administration (VA) is an ideal setting to examine the impact of the patient-centered medical home (PCMH) on diabetes outcomes...
  58. McClements L, Annett S, Yakkundi A, Robson T. The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases. Curr Mol Pharmacol. 2015;9:165-79 pubmed
    ..Due to this unique structure these proteins are able to facilitate protein-protein interactions which can impact significantly on a range of cellular processes such as cell signalling, differentiation, cell cycle progression, ..
  59. Urone N, Di Marco V, Cacopardo B, Craxì A, Ferraro D. Impact of HBV genotypes A and D genetic variability on infection evolution. Infect Genet Evol. 2015;33:281-7 pubmed publisher
    ..Moreover, the analysis of circulation of new HBV antigenic variants is fundamental for the epidemiological surveys and for the evaluation of the impact of viral evolution on vaccine prophylaxis strategies.
  60. Vermeulen E, Maertens J, De Bel A, Nulens E, Boelens J, Surmont I, et al. Nationwide Surveillance of Azole Resistance in Aspergillus Diseases. Antimicrob Agents Chemother. 2015;59:4569-76 pubmed publisher
    ..The prevalence and clinical impact of azole resistance in different patient populations are currently unclear...
  61. Zhang Y, Tao Y, Zhang H, Wang L, Sun G, Sun X, et al. Effect of di-n-butyl phthalate on root physiology and rhizosphere microbial community of cucumber seedlings. J Hazard Mater. 2015;289:9-17 pubmed publisher
    ..Root protein content and root activity were observed to decrease. From the ultrastructural micrographs, visible impact on the mitochondria, endoplasmic reticulum and vacuole were detected...
  62. Pelzer U, Opitz B, Deutschinoff G, Stauch M, Reitzig P, Hahnfeld S, et al. Efficacy of Prophylactic Low-Molecular Weight Heparin for Ambulatory Patients With Advanced Pancreatic Cancer: Outcomes From the CONKO-004 Trial. J Clin Oncol. 2015;33:2028-34 pubmed publisher
    ..use of enoxaparin or chemotherapy alone to investigate the probable reduction in symptomatic VTEs and the impact on survival. A total of 312 patients were recruited as one of the protocol end points was reached...
  63. Hochstenbach L, Courtens A, Zwakhalen S, van Kleef M, de Witte L. Self-management support intervention to control cancer pain in the outpatient setting: a randomized controlled trial study protocol. BMC Cancer. 2015;15:416 pubmed publisher
    Pain is a prevalent and distressing symptom in patients with cancer, having an enormous impact on functioning and quality of life...
  64. Saab S, Alper T, Sernas E, Pruthi P, Alper M, Sundaram V. Hospitalized Patients with Cirrhosis Should Be Screened for Clostridium difficile Colitis. Dig Dis Sci. 2015;60:3124-9 pubmed publisher
    ..The aim of this study was to assess the pharmacoeconomic impact of CDI screening on hospitalized patients with cirrhosis...
  65. de Moraes W, Melara T, de Souza P, Guimarães F, Bozi L, Brum P, et al. Impact of leucine supplementation on exercise training induced anti-cardiac remodeling effect in heart failure mice. Nutrients. 2015;7:3751-66 pubmed publisher
    ..Our results provide evidence for the modest impact of leucine supplementation on cardiac structure and function in exercised heart failure mice...
  66. Leca M, Bornet C, Montana M, Curti C, Vanelle P. Meningococcal vaccines: Current state and future outlook. Pathol Biol (Paris). 2015;63:144-51 pubmed publisher
    ..Another serogroup meningococcal vaccine, Trumemba(®), was also recently licensed in United States. Like any drug, Bexsero(®) and Trumemba(®) will require close observation to assess their impact on meningococcal epidemiology.
  67. Cristobal I, Neyro J, Lete I. The new LNG-releasing IUS: a new opportunity to reduce the burden of unintended pregnancy. Eur J Obstet Gynecol Reprod Biol. 2015;190:58-64 pubmed publisher
    ..They have received much attention in adolescents given the strong impact they have on their present and future lives...
  68. Andrews J, Psaltis P, Bayturan O, Shao M, Stegman B, Elshazly M, et al. Warfarin Use Is Associated With Progressive Coronary Arterial Calcification: Insights From Serial Intravascular Ultrasound. JACC Cardiovasc Imaging. 2017;: pubmed publisher
    ..The longitudinal impact of warfarin on serial coronary artery calcification in vivo in humans is unknown...
  69. Lambert S, Beatty L, McElduff P, Levesque J, Lawsin C, Jacobsen P, et al. A systematic review and meta-analysis of written self-administered psychosocial interventions among adults with a physical illness. Patient Educ Couns. 2017;100:2200-2217 pubmed publisher
    ..interventions were efficacious for depression, distress, and self-efficacy; only guided interventions had an impact on anxiety. Findings showed that written self-administered interventions show promise across a number of outcomes...
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    ..A randomised controlled trial evaluated the impact of a Proficiency based Stepwise Endovascular Curricular Training program (PROSPECT) on the acquisition of ..
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    ..A longer distance between ventricular leads may improve response. To study the impact of the true three-dimensional interlead distance (ILD) on outcomes...
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    ..Decreasing prescription rates in some drug sub-classes were observed. The potential impact of these changes on the quality of symptom control for cancer patients needs further investigation.
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    This study sought to explore the impact of smoking reduction on suicidality (suicide ideation and behaviour) among people with a psychotic disorder (n=235) who participated in a randomized trial of a healthy lifestyle intervention trial...
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    ..of Saccharomyces cerevisiae replication factor C (RFC) clamp loader, respectively, and assessed the impact on multiple transient events in the reaction: proliferating cell nuclear antigen (PCNA) clamp binding/opening/..
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    ..of the visible and invisible wounds of war for service members, little to no information exists regarding the impact parental service has on the physical, psychological, and behavioral health of military children...
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    ..Confirmation of these findings in larger, prospective cohorts is necessary.Bone Marrow Transplantation advance online publication, 13 November 2017; doi:10.1038/bmt.2017.203...
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    ..The impact of this campaign has been estimated using the descriptive analysis of the relationship between the number of calls ..
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    Cannabis is the most widely consumed illicit drug. Although it is too early to confirm the impact of legalization, the use of cannabis appears to be on the rise in some countries due to its authorization for medical/recreational purposes...
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    ..In this review, we provide an overview on how different carbon substrates and metabolic pathways impact neurotransmission, and the potential implications for neurological disorders in which neuronal excitability is ..
  86. Araújo Y, de Góis M, Junior L, Carvalho M. Carbon footprint associated with four disposal scenarios for urban pruning waste. Environ Sci Pollut Res Int. 2018;25:1863-1868 pubmed publisher
    ..Software SimaPro was utilized for the quantification of the carbon footprint, with the IPCC 2013 GWP 100y impact evaluation method...
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    Connexin43 (Cx43) gap junctions expressed in astrocytes can significantly impact neuronal survival in stroke. However, little is known regarding Cx43 spatial and temporal expression during the initial stages of brain ischemia...
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    ..Youth social problems are difficult to change; therefore, targeting internalizing problems may be an effective way to reduce the social problems of children of parents with a history of depression...
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    ..Overall, our data indicate that a diet rich in n-3 PUFA has a beneficial effect on the longevity of a murine model of α-synucleinopathy without a major impact on the dopamine system and motor impairments, nor αSyn levels.
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    ..In particular, the impact of oral promethazine, widely used for treating motion sickness, on vestibular perceptual thresholds has not ..
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    ..treatment, an elevation of its concentration in the environment is observed that might lead to a serious impact on human and environmental health...
  92. Mitsuhashi K, Hashimoto Y, Hamaguchi M, Obora A, Kojima T, Fukuda T, et al. Impact of fatty liver disease and metabolic syndrome on incident type 2 diabetes; a population based cohort study. Endocr J. 2017;64:1105-1114 pubmed publisher
    ..38 (95% CI 1.07-1.79, p=0.013) in MetS with fatty liver. Fatty liver affects more on the risk of incident diabetes than MetS. To prevent the further risk of diabetes, we should pay more attention to fatty liver...
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    ..therapy treatments (in addition to the standard positioning recommendations) as well as to determine the feasibility of this methodology to conduct an outcome research investigating the impact of this intervention for infants with NSOP.
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    ..has been widely studied in a variety of fields from biology to computer science, still little is known about the impact of environmental changes on an artificial chemical evolving system outside of computer simulations...
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    ..We investigated the impact of PTP1B deficiency during NAFLD, particularly in non-alcoholic steatohepatitis (NASH)...
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    ..and a brief overview of practical issues pertaining to DECT implementation, including those related to workflow impact of DECT; and a discussion of various applications of DECT for the evaluation of the neck, especially in oncology.
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    ..investigations have been conducted on how 1, 25-dihydroxyvitamin D3 and mechanical stimuli separately impact osteoblasts...