CCS

Summary

Gene Symbol: CCS
Description: copper chaperone for superoxide dismutase
Alias: copper chaperone for superoxide dismutase, superoxide dismutase copper chaperone
Species: human
Products:     CCS

Top Publications

  1. Casareno R, Waggoner D, Gitlin J. The copper chaperone CCS directly interacts with copper/zinc superoxide dismutase. J Biol Chem. 1998;273:23625-8 pubmed
    ..The delivery of copper to SOD1 is mediated through a soluble factor identified as the copper chaperone for SOD1 (CCS)...
  2. Bartnikas T, Waggoner D, Casareno R, Gaedigk R, White R, Gitlin J. Chromosomal localization of CCS, the copper chaperone for Cu/Zn superoxide dismutase. Mamm Genome. 2000;11:409-11 pubmed
  3. Rothstein J, Dykes Hoberg M, Corson L, Becker M, Cleveland D, Price D, et al. The copper chaperone CCS is abundant in neurons and astrocytes in human and rodent brain. J Neurochem. 1999;72:422-9 pubmed
    Copper trafficking in mammalian cells is highly regulated. CCS is a copper chaperone that donates copper to the antioxidant enzyme copper/zinc superoxide dismutase 1 (SOD 1)...
  4. Rae T, Schmidt P, Pufahl R, Culotta V, O Halloran T. Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase. Science. 1999;284:805-8 pubmed
    The copper chaperone for the superoxide dismutase (CCS) gene is necessary for expression of an active, copper-bound form of superoxide dismutase (SOD1) in vivo in spite of the high affinity of SOD1 for copper (dissociation constant = 6 ..
  5. Moore S, Chen M, Cox D. Cloning and mapping of murine superoxide dismutase copper chaperone (Ccsd) and mapping of the human ortholog. Cytogenet Cell Genet. 2000;88:35-7 pubmed
    ..9% identical to human CCS. Using a mouse x hamster radiation hybrid panel, we mapped Ccsd to a proximal position on mouse chromosome 19...
  6. Sharma K, Yadav S, Valluru B, Liu L. Significance of MRI in the diagnosis and differentiation of clear cell sarcoma of tendon and aponeurosis (CCSTA): A case report. Medicine (Baltimore). 2018;97:e11012 pubmed publisher
    ..Clear cell Sarcoma of Tendon and Aponeurosis (CCSTA) or CCS of Soft parts...
  7. Coticchio G, Dal Canto M, Mignini Renzini M, Guglielmo M, Brambillasca F, Turchi D, et al. Oocyte maturation: gamete-somatic cells interactions, meiotic resumption, cytoskeletal dynamics and cytoplasmic reorganization. Hum Reprod Update. 2015;21:427-54 pubmed publisher
    ..Cumulus cells (CCs) are central to the process of maturation, providing the oocyte with metabolic support and regulatory cues...
  8. Kaler S. Inborn errors of copper metabolism. Handb Clin Neurol. 2013;113:1745-54 pubmed publisher
    ..syndrome caused by mutations in an acetyl CoA transporter needed for acetylation of one or more copper proteins, 2) CCS deficiency caused by mutations in the copper chaperone to SODI, and 3) MEDNIK syndrome, which revealed that ..
  9. Kong D, Wang Y, Liu Y, Zhang Z, Liu G, Qi W, et al. The association between blood lipid and phlegm turbidity syndrome of angina pectoris: a systematic review and meta-analysis. Complement Ther Med. 2014;22:801-13 pubmed publisher
    ..TG) in phlegm syndrome group showed superior to non-phlegm syndrome group in the rest subgroups except for the non-CCS (Cold coagulating syndrome)-non-YDS subgroup...

More Information

Publications141 found, 100 shown here

  1. Djuric O, Jovanovic S, Stosovic B, Tosic T, Jovanovic M, Markovic Denic L. Antimicrobial resistance of selected invasive bacteria in a tertiary care center: results of a prospective surveillance study. J Infect Dev Ctries. 2016;10:1325-1331 pubmed publisher
    ..and resistance patterns of eight invasive clinically relevant bacteria surveyed in the Clinical Center of Serbia (CCS) in Belgrade...
  2. Kratz M, Schirmer S, Baumhakel M, Bohm M. Improvement of endothelial function in a murine model of mild cholesterol-induced atherosclerosis by mineralocorticoid antagonism. Atherosclerosis. 2016;251:291-298 pubmed publisher
    ..Endothelial function was measured in aortic rings and corpora cavernosal strips (CCs)...
  3. Zetzsche A, Schunter N, Zentek J, Pieper R. Accumulation of copper in the kidney of pigs fed high dietary zinc is due to metallothionein expression with minor effects on genes involved in copper metabolism. J Trace Elem Med Biol. 2016;35:1-6 pubmed publisher
    ..Kidney mRNA expression of Zn transporter ZnT1 and ZIP4, genes involved in Cu metabolism (Ctr1, Atox1, SOD1, ATP7A, CCS, CP) and divalent metal ion transport (DMT1) and binding (MT-1a, MT-2b, MT-3) were determined...
  4. Goldberg J, Fisher D, Demetri G, Neuberg D, Allsop S, Fonseca C, et al. Biologic Activity of Autologous, Granulocyte-Macrophage Colony-Stimulating Factor Secreting Alveolar Soft-Part Sarcoma and Clear Cell Sarcoma Vaccines. Clin Cancer Res. 2015;21:3178-86 pubmed publisher
    Alveolar soft-part sarcoma (ASPS) and clear cell sarcoma (CCS) are rare mesenchymal malignancies driven by chromosomal translocations that activate members of the microphthalmia transcription factor (MITF) family...
  5. Arias Alvarez M, Garcia Garcia R, López Tello J, Rebollar P, Gutierrez Adan A, Lorenzo P. In vivo and in vitro maturation of rabbit oocytes differently affects the gene expression profile, mitochondrial distribution, apoptosis and early embryo development. Reprod Fertil Dev. 2017;29:1667-1679 pubmed publisher
    ..In the present study we compared some gene markers of oocytes and cumulus cells (CCs) from immature, in vivo-matured and IVM oocytes...
  6. Chochua S, Metcalf B, Li Z, Rivers J, Mathis S, Jackson D, et al. Population and Whole Genome Sequence Based Characterization of Invasive Group A Streptococci Recovered in the United States during 2015. MBio. 2017;8: pubmed publisher
    ..Sixty-four M protein gene (emm) types were identified among 69 clonal complexes (CCs), including one CC of Streptococcus dysgalactiae subsp...
  7. Chemaitilly W, Li Z, Huang S, Ness K, Clark K, Green D, et al. Anterior hypopituitarism in adult survivors of childhood cancers treated with cranial radiotherapy: a report from the St Jude Lifetime Cohort study. J Clin Oncol. 2015;33:492-500 pubmed publisher
    ..and adrenocorticotropic hormone deficiency (ACTHD) after cranial radiotherapy (CRT) in childhood cancer survivors (CCS) and assess the impact of untreated deficiencies...
  8. Simerman A, Hill D, Grogan T, Elashoff D, Clarke N, Goldstein E, et al. Intrafollicular cortisol levels inversely correlate with cumulus cell lipid content as a possible energy source during oocyte meiotic resumption in women undergoing ovarian stimulation for in vitro fertilization. Fertil Steril. 2015;103:249-57 pubmed publisher
    ..fluid (FF) cortisol levels affect cumulus cell (CC) lipid content during oocyte meiotic resumption, and whether CCs express genes for glucocorticoid action. Prospective cohort study. Academic medical center...
  9. Ulrich Merzenich G, Hartbrod F, Kelber O, Muller J, Koptina A, Zeitler H. Salicylate-based phytopharmaceuticals induce adaptive cytokine and chemokine network responses in human fibroblast cultures. Phytomedicine. 2017;34:202-211 pubmed publisher
    ..Phytopharmaceuticals, common adjuvant therapies, are known modulators of a broad spectrum of CCs, but as complex mixtures with multiple targets they have not been systematically investigated...
  10. Jans C, Merz A, Johler S, Younan M, Tanner S, Kaindi D, et al. East and West African milk products are reservoirs for human and livestock-associated Staphylococcus aureus. Food Microbiol. 2017;65:64-73 pubmed publisher
    ..aureus of the three countries is genetically diverse comprising human and livestock-associated clonal complexes (CCs) predominated by the CC5 (n = 10) and CC30 (n = 9) isolates...
  11. Kowsar R, Iranshahi V, Sadeghi N, Riasi A, Miyamoto A. Urea influences amino acid turnover in bovine cumulus-oocyte complexes, cumulus cells and denuded oocytes, and affects in vitro fertilization outcome. Sci Rep. 2018;8:12191 pubmed publisher
    ..evaluated in the 24-h spent media of specimens (cell types), bovine cumulus-oocyte complexes (COCs), cumulus cells (CCs), or denuded oocytes (DOs)...
  12. Song M, Bai Y, Xu J, Carter M, Shi C, Shi X. Genetic diversity and virulence potential of Staphylococcus aureus isolates from raw and processed food commodities in Shanghai. Int J Food Microbiol. 2015;195:1-8 pubmed publisher
    ..A total of 16 clonal complexes (CCs), 34 staphylococcal protein A (spa) types, and 6 accessory gene regulator (agr) allelic groups were identified and ..
  13. McDonald J, Kracko D, Doyle Eisele M, Garner C, Wegerski C, SENFT A, et al. Carbon capture and sequestration: an exploratory inhalation toxicity assessment of amine-trapping solvents and their degradation products. Environ Sci Technol. 2014;48:10821-8 pubmed publisher
    Carbon dioxide (CO2) absorption with aqueous amine solvents is a method of carbon capture and sequestration (CCS) from flue gases...
  14. Xie H, Zhu S, Zhang J, Wen J, Yuan H, Pan L, et al. Glucose metabolism during in vitro maturation of mouse oocytes: An study using RNA interference. J Cell Physiol. 2018;233:6952-6964 pubmed publisher
    ..and/or toxicity, and culture of COCs cannot differentiate whether glucose metabolism of cumulus cells (CCs) or that of the oocyte supports oocyte maturation, results from the previous studies must be verified by silencing ..
  15. Luan Y, Ruan Y, Wang T, Zhuan L, Wen Z, Chen R, et al. Preserved Erectile Function in the Aged Transgenic Rat Harboring Human Tissue Kallikrein 1. J Sex Med. 2016;13:1311-1322 pubmed publisher
    ..Rats' erectile function was evaluated by the cavernous nerve electrostimulation method. Then, CCs were collected for verification of hKLK1 followed by measurement of nitric oxide (NO)-cyclic guanosine ..
  16. McMillan K, Moore S, McAuley C, Fegan N, Fox E. Characterization of Staphylococcus aureus isolates from raw milk sources in Victoria, Australia. BMC Microbiol. 2016;16:169 pubmed publisher
    ..2 new STs, eBURST analysis predicted all other STs to be founding members of their associated clonal complexes (CCs)...
  17. Chen H, Liu C, Jiang H, Gao Y, Xu M, Wang J, et al. Regulatory Role of miRNA-375 in Expression of BMP15/GDF9 Receptors and its Effect on Proliferation and Apoptosis of Bovine Cumulus Cells. Cell Physiol Biochem. 2017;41:439-450 pubmed publisher
    ..it is not clear which genes mediate and regulate the effects of the BMP15/GDF9 proteins on bovine cumulus cells (CCs). Our earlier study showed that BMPR2 is a gene that is directly targeted and regulated by miR-375...
  18. Montanari A, Lazzeroni D, Pelà G, Crocamo A, Lytvyn Y, Musiari L, et al. Calcium channel blockade blunts the renal effects of acute nitric oxide synthase inhibition in healthy humans. Am J Physiol Renal Physiol. 2017;312:F870-F878 pubmed publisher
    Our aim was to investigate whether blockade of calcium channels (CCs) or angiotensin II type 1 receptors (AT1R) modulates renal responses to nitric oxide synthesis inhibition (NOSI) in humans...
  19. Pomorska Wesołowska M, Chmielarczyk A, Chlebowicz M, Ziółkowski G, Szczypta A, Natkaniec J, et al. Virulence and antimicrobial resistance of Staphylococcus aureus isolated from bloodstream infections and pneumonia in Southern Poland. J Glob Antimicrob Resist. 2017;11:100-104 pubmed publisher
    ..the BURP algorithm and the Ridom SpaServer database, spa types were clustered into different clonal complexes (spa-CCs). MRSA strains were observed at a prevalence of 26.7%, but 88...
  20. Cai L, Jeon Y, Yoon J, Hwang S, Kim E, Park K, et al. The effects of human recombinant granulocyte-colony stimulating factor treatment during in vitro maturation of porcine oocyte on subsequent embryonic development. Theriogenology. 2015;84:1075-87 pubmed publisher
    ..of G-CSF and its receptor were analyzed by polymerase chain reaction in granulosa cells (GCs), CL, cumulus cells (CCs), and oocytes...
  21. Nemade N, Shukla U, Wagholikar G. Cronkhite Canada syndrome complicated by pulmonary embolism-A case report. Int J Surg Case Rep. 2017;30:17-22 pubmed publisher
    Cronkhite Canada Syndrome (CCS) is a rare syndrome, described in 1955 by Americans, Leonard Wolsey Cronkhite and Wilma Jeanne Canada in the New England Journal of Medicine [1]. About 450 cases have been reported...
  22. Cui Y, Palii S, Innes C, Paules R. Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents. Cell Cycle. 2014;13:3541-50 pubmed publisher
    ..Our data suggests that while depletion of ATR or ATM alone in wild-type human mammary epithelial cell cultures (HME-CCs) has little effect on radiosensitivity or IR-induced G2/M checkpoint arrest, depletion of ATR in ATM-deficient ..
  23. Adler A, Miller Roll T, Assous M, Geffen Y, Paikin S, Schwartz D, et al. A multicenter study of the clonal structure and resistance mechanism of KPC-producing Escherichia coli isolates in Israel. Clin Microbiol Infect. 2015;21:230-5 pubmed publisher
    ..The most common clones were ST-131 and ST-410, identified in 21 isolates (23%). Dominant clonal complexes (CCs) were CC131 (n = 16), CC410 (n = 14), CC10 (n = 17), and CC-69 (n = 6)...
  24. Black J, Reaven N, Funk S, McGaughey K, Ohayon M, Guilleminault C, et al. Medical comorbidity in narcolepsy: findings from the Burden of Narcolepsy Disease (BOND) study. Sleep Med. 2017;33:13-18 pubmed publisher
    ..conditions, identified by the appearance of >1 diagnosis code(s) mapped to a Clinical Classification System (CCS) level 1 category any time during the study period, and on specific subcategories, including recognized narcolepsy ..
  25. Alagoz M, Chiang S, Sharma A, El Khamisy S. ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells. PLoS ONE. 2013;8:e58239 pubmed publisher
    ..created by oxidative stress or by collision of transcription machinery with topoisomerase I intermediates (Top1-CCs)...
  26. Zheng L, Hills T, Fennell P. Phase evolution, characterisation, and performance of cement prepared in an oxy-fuel atmosphere. Faraday Discuss. 2016;192:113-124 pubmed
    ..Carbon capture and storage (CCS) has been identified as a vital technology for decarbonising the sector...
  27. Nishijima T, Muss H, Shachar S, Tamura K, Takamatsu Y. Prognostic value of lymphocyte-to-monocyte ratio in patients with solid tumors: A systematic review and meta-analysis. Cancer Treat Rev. 2015;41:971-8 pubmed publisher
    ..LMR lower than the cut-off was associated with poor OS (HR, 1.73; 95% CI, 1.55-1.93; P<0.001), CCS (HR, 1.56; 95% CI, 1.27-1.91; P<0.001) and DFS (HR, 1.56; 95% CI, 1.31-1.86; P<0.001)...
  28. Ulrich G, Parstorfer M. Effects of Plyometric Versus Concentric and Eccentric Conditioning Contractions on Upper-Body Postactivation Potentiation. Int J Sports Physiol Perform. 2017;12:736-741 pubmed publisher
    There are limited data on postactivation potentiation's (PAP) effects after plyometric conditioning contractions (CCs), especially in the upper body...
  29. Karoui M, Rullier A, Luciani A, Bonnetain F, Auriault M, Sarran A, et al. Neoadjuvant FOLFOX 4 versus FOLFOX 4 with Cetuximab versus immediate surgery for high-risk stage II and III colon cancers: a multicentre randomised controlled phase II trial--the PRODIGE 22--ECKINOXE trial. BMC Cancer. 2015;15:511 pubmed publisher
    ..Preoperative chemotherapy is an attractive concept for these CCs and has the potential to impact upon both of these causes of failure...
  30. Han J, Wang C, Liu X, Wang Y, Liu Z, Jiang J. Atomic-Level Mechanisms of Nucleation of Pure Liquid Metals during Rapid Cooling. Chemphyschem. 2015;16:3916-27 pubmed publisher
    ..as functions of cluster size in units of amorphous clusters (ACs) and body-centered cubic crystalline clusters (BCC-CCs)...
  31. Warschawski Y, Sharfman Z, Berger O, Steinberg E, Amar E, Snir N. Dynamic locking plate vs. simple cannulated screws for nondisplaced intracapsular hip fracture: A comparative study. Injury. 2016;47:424-7 pubmed publisher
    ..We compared a dynamic locking plate with the standard cancellous cannulated screws (CCS) for treatment of nondisplaced ICHF...
  32. Appoo J, Bozinovski J, Chu M, El Hamamsy I, Forbes T, Moon M, et al. Canadian Cardiovascular Society/Canadian Society of Cardiac Surgeons/Canadian Society for Vascular Surgery Joint Position Statement on Open and Endovascular Surgery for Thoracic Aortic Disease. Can J Cardiol. 2016;32:703-13 pubmed publisher
    In 2014, the Canadian Cardiovascular Society (CCS) published a position statement on the management of thoracic aortic disease addressing size thresholds for surgery, imaging modalities, medical therapy, and genetics...
  33. Zhou J, Liu Y, Huang L, Tan Y, Li X, Zhang H, et al. Validation and comparison of four models to calculate pretest probability of obstructive coronary artery disease in a Chinese population: A coronary computed tomographic angiography study. J Cardiovasc Comput Tomogr. 2017;11:317-323 pubmed publisher
    ..We identified 5743 consecutive patients with suspected stable CAD who underwent coronary calcium scoring (CCS) and coronary CCTA...
  34. Kim Y, He W, Ko D, Chung H, Yoo G. Increased N2O emission by inhibited plant growth in the CO2 leaked soil environment: Simulation of CO2 leakage from carbon capture and storage (CCS) site. Sci Total Environ. 2017;607-608:1278-1285 pubmed publisher
    ..to increase due to anthropogenic activity, and geological CO2 storage via carbon capture and storage (CCS) technology can be an effective way to mitigate global warming due to CO2 emission...
  35. Higashi R, Craddock Lee S, Leonard T, Cuate E, Cole J, Pruitt S. Multiple Comorbidities and Interest in Research Participation Among Clients of a Nonprofit Food Distribution Site. Clin Transl Sci. 2015;8:584-90 pubmed publisher
    ..Focus groups were conducted in English (n = 4) and Spanish (n = 4) with clients of Crossroads Community Services (CCS), the largest distributor of North Texas Food Bank...
  36. Brignardello E, Felicetti F, Castiglione A, Nervo A, Biasin E, Ciccone G, et al. Gonadal status in long-term male survivors of childhood cancer. J Cancer Res Clin Oncol. 2016;142:1127-32 pubmed publisher
    ..prevalence of gonadal dysfunction and the associated risk factors in a cohort of male childhood cancer survivors (CCS). Gonadal function was evaluated measuring FSH, LH, inhibin B and total testosterone levels...
  37. Jayasinghe S. Describing complex clinical scenarios at the bed-side: Is a systems science approach useful? Exploring a novel diagrammatic approach to facilitate clinical reasoning. BMC Med Educ. 2016;16:264 pubmed
    Clinicians often encounter patients having complex clinical scenarios (CCS) where diverse and dynamic diagnostic and therapeutic issues interact...
  38. Elmedany S, Naga S, Elsharkawy R, Mahrous R, Elnaggar A. Novel urinary biomarkers and the early detection of acute kidney injury after open cardiac surgeries. J Crit Care. 2017;40:171-177 pubmed publisher
    ..This prospective study was carried out on 45 adult patients, of both sexes, Cleveland score(CCS) (0-5) and scheduled for elective coronary artery bypass graft (CABG) surgery in Alexandria Main University ..
  39. Day M, Doumith M, Abernethy J, Hope R, Reynolds R, Wain J, et al. Population structure of Escherichia coli causing bacteraemia in the UK and Ireland between 2001 and 2010. J Antimicrob Chemother. 2016;71:2139-42 pubmed publisher
    ..Four hundred and forty-eight STs were identified, but five of these, and their associated clonal complexes (CCs), accounted for 58.4% (1264 of 2166) of isolates: CC73 was the most common (20.7%), followed by CC131 (13...
  40. Szarpak L, Truszewski Z, Czyżewski L, Gaszynski T, Rodríguez Núñez A. A comparison of the McGrath-MAC and Macintosh laryngoscopes for child tracheal intubation during resuscitation by paramedics. A randomized, crossover, manikin study. Am J Emerg Med. 2016;34:1338-41 pubmed publisher
    ..Our objective was to assess the impact of CPR (with and without chest compressions [CCs]) on the success and time to intubation (TTI) with the Macintosh laryngoscope vs the McGrath video laryngoscope on ..
  41. Sakwa Novak M, Yoo C, Tan S, Rashidi F, Jones C. Poly(ethylenimine)-Functionalized Monolithic Alumina Honeycomb Adsorbents for CO2 Capture from Air. ChemSusChem. 2016;9:1859-68 pubmed publisher
    ..Target CO2 capture applications, such as postcombustion carbon capture and sequestration (CCS) from power plant flue gases or CO2 extraction directly from ambient air (DAC), require high flow rates of gas to ..
  42. Munakata Y, Ichinose T, Ogawa K, Itami N, Tasaki H, Shirasuna K, et al. Relationship between the number of cells surrounding oocytes and energy states of oocytes. Theriogenology. 2016;86:1789-1798.e1 pubmed publisher
    ..first examined the relationship among the average number of GCs per follicle, the average number of cumulus cells (CCs) per oocyte, and the average lipid content in oocytes that developed in vivo within individual donor gilts...
  43. Shao L, Yan A, Lebovic G, Wong H, Kirpalani A, Deva D. Prognostic value of visually detected coronary artery calcification on unenhanced non-gated thoracic computed tomography for prediction of non-fatal myocardial infarction and all-cause mortality. J Cardiovasc Comput Tomogr. 2017;11:196-202 pubmed publisher
    ..was examined by a single reader blinded to clinical data and outcome, using 1) the Agatston coronary calcium score (CCS), 2) visual CAC and 3) number of visually calcified coronary arteries. Visible CAC was identified in 201 (49...
  44. Magrini V, Gao X, Rosa B, McGrath S, Zhang X, Hallsworth Pepin K, et al. Improving eukaryotic genome annotation using single molecule mRNA sequencing. BMC Genomics. 2018;19:172 pubmed publisher
    ..We sequenced 192,888 circular consensus sequences (CCS) derived from cDNAs generated using the CloneTech SMARTer system...
  45. Zhai H, Ou Y, Rubin E. Opportunities for Decarbonizing Existing U.S. Coal-Fired Power Plants via CO2 Capture, Utilization and Storage. Environ Sci Technol. 2015;49:7571-9 pubmed publisher
    ..A complementary CO2 emission trading program can provide additional economic incentives for the deployment of CCS with 90% CO2 capture...
  46. Mosquera C, Koutlas N, Edwards K, Strickland A, Vohra N, Zervos E, et al. Impact of malnutrition on gastrointestinal surgical patients. J Surg Res. 2016;205:95-101 pubmed publisher
    ..6%), white (60.2%), underwent elective procedures (77.6%), had a Charlson comorbidity score (CCS) of 3-5 (40.0%), and a Clavien-Dindo complication (CDC) grade of 0-II (81.2%). A total of 93 (19...
  47. Patel M, Luthra S, Shamblin S, Arora K, Krzyzaniak J, Taylor L. Impact of solid-state form on the disproportionation of miconazole mesylate. Mol Pharm. 2017;: pubmed publisher
    ..when mixed with basic excipients, namely tribasic sodium phosphate dodecahydrate (TSPd) and croscarmellose sodium (CCS), and exposed to moderate relative humidity storage conditions...
  48. Yuan S, Zhang P, Yang Z, Lv L, Tang S, Liang B. Successive grafting of poly(hydroxyethyl methacrylate) brushes and melamine onto chitosan microspheres for effective Cu(II) uptake. Int J Biol Macromol. 2018;109:287-302 pubmed publisher
    Cross-linked chitosan (CCS) microspheres tethered with melamine-conjugated poly(hydroxyethyl methacrylate) (PHEMA) brushes were synthesized by combination of surface-initiated atom transfer radical polymerization (ATRP) of HEMA and ..
  49. Akashi S, Downard K. Effect of charge on the conformation of highly basic peptides including the tail regions of histone proteins by ion mobility mass spectrometry. Anal Bioanal Chem. 2016;408:6637-48 pubmed publisher
    ..maximum charge, or most abundant charge state, that the peptides support and their average collision cross section (CCS) values measured by ion mobility mass spectrometry...
  50. Goodrich D, Tao X, Bohrer C, Lonczak A, Xing T, Zimmerman R, et al. A randomized and blinded comparison of qPCR and NGS-based detection of aneuploidy in a cell line mixture model of blastocyst biopsy mosaicism. J Assist Reprod Genet. 2016;33:1473-1480 pubmed
    ..representing a possible limitation to the clinical predictive value of comprehensive chromosome screening (CCS) from a single biopsy...
  51. Blair L, Cox T, Huntington C, Groene S, Prasad T, Lincourt A, et al. The effect of component separation technique on quality of life (QOL) and surgical outcomes in complex open ventral hernia repair (OVHR). Surg Endosc. 2017;31:3539-3546 pubmed publisher
    ..outcomes were obtained preoperatively and at 1, 6 and 12 months postoperatively using the Carolinas Comfort Scale (CCS). A CCS of 2 (mild but bothersome discomfort) or greater was considered symptomatic...
  52. Duquesne F, Houssin E, Sevin C, Duytschaever L, Tapprest J, Fretin D, et al. Development of a multilocus sequence typing scheme for Rhodococcus equi. Vet Microbiol. 2017;210:64-70 pubmed publisher
    ..One of the six CCs (CC3) is not host-specific, suggesting potential exchanges between different R. equi reservoirs...
  53. Quintero Moreno B, Araque M. Molecular characterisation of multidrug-resistant pneumococcal clones colonising healthy children in Mérida, Venezuela. J Glob Antimicrob Resist. 2018;14:45-50 pubmed publisher
    ..MDR pneumococci were related to six clonal complexes (CCs), largely CC156 or CC15. Limited diversity in pbp2a,2b,2x-RFLP profiles within each clone was observed...
  54. Xiao C, Pérez L, Russell D. Effects of charge states, charge sites and side chain interactions on conformational preferences of a series of model peptide ions. Analyst. 2015;140:6933-44 pubmed publisher
    ..Collision cross sections (CCS) of [M + 2H](2+) and [M + 3H](3+) ions for a series of model peptides, viz...
  55. Ganesh V, Agarwal A, Popovic M, Cella D, McDonald R, Vuong S, et al. Comparison of the FACT-C, EORTC QLQ-CR38, and QLQ-CR29 quality of life questionnaires for patients with colorectal cancer: a literature review. Support Care Cancer. 2016;24:3661-8 pubmed publisher
    ..in four domains of well-being (physical, emotional, social, and functional), and the Colorectal Cancer Subscale (CCS)...
  56. Pacholarz K, Burnley R, Jowitt T, Ordsmith V, Pisco J, Porrini M, et al. Hybrid Mass Spectrometry Approaches to Determine How L-Histidine Feedback Regulates the Enzyzme MtATP-Phosphoribosyltransferase. Structure. 2017;25:730-738.e4 pubmed publisher
    ..The experimental collision cross-section (DTCCSHe) decreases from 76.6 to 73.5 nm2 upon ligand binding at pH 6...
  57. Alejandre García T, Peña Del Castillo J, Hernandez Cruz A. GABAA receptor: a unique modulator of excitability, Ca2+ signaling, and catecholamine release of rat chromaffin cells. Pflugers Arch. 2018;470:67-77 pubmed publisher
    ..together with CA, ATP, and opioids in response to physiological stimuli, playing an autocrine-paracrine role on CCs. The reported paradoxical "dual action" of GABAA-R activation (enhancement of CA secretion and ..
  58. Millard S, Shofer J, Braff D, Calkins M, Cadenhead K, Freedman R, et al. Prioritizing schizophrenia endophenotypes for future genetic studies: An example using data from the COGS-1 family study. Schizophr Res. 2016;174:1-9 pubmed publisher
    ..the utility of a multivariate index to improve discrimination between SZ and healthy community comparison subjects (CCS)...
  59. Seifarth C, Börner L, Siegmund B, Buhr H, Ritz J, Gröne J. Impact of staged surgery on quality of life in refractory ulcerative colitis. Surg Endosc. 2017;31:643-649 pubmed publisher
    ..procedure was completed, and evaluation of QoL was performed by specific questionnaires (IBDQ, FIQoL, SF-12, CCS) up to 20 years after ileostomy closure. Data were collected within the framework of a prospective study...
  60. Côté S, Larose M, Geoffroy M, Laurin J, Vitaro F, Tremblay R, et al. Testing the impact of a social skill training versus waiting list control group for the reduction of disruptive behaviors and stress among preschool children in child care: the study protocol for a cluster randomized trial. BMC Psychol. 2017;5:29 pubmed publisher
    Most preschoolers growing up in western industrialized countries receive child care services (CCS) during the day, while their parents are at work. Meta-analytic data suggest that CCS represent a stressful experience for preschoolers...
  61. Haler J, Morsa D, Lecomte P, Jerome C, Far J, De Pauw E. Predicting Ion Mobility-Mass Spectrometry trends of polymers using the concept of apparent densities. Methods. 2018;144:125-133 pubmed publisher
    ..Here, we propose the analysis of the Collision Cross-Section (CCS) trends of synthetic homopolymers based on a fitting method which does not rely on computational chemistry a ..
  62. Abelairas Gomez C, Vázquez González P, López García S, Palacios Aguilar J, Padrón Cabo A, Rodriguez Nunez A. Cardiopulmonary Resuscitation Quality by Helicopter Rescue Swimmers While Flying. Air Med J. 2016;35:288-91 pubmed publisher
    ..Incomplete chest re-expansion was observed in 19% of on land and 26% in-flight CCs. CPR quality was maintained throughout the 5-minute challenges...
  63. Talati S, Zhai H, Morgan M. Viability of Carbon Capture and Sequestration Retrofits for Existing Coal-Fired Power Plants under an Emission Trading Scheme. Environ Sci Technol. 2016;50:12567-12574 pubmed
    ..in Texas we assess the economic feasibility of retrofitting existing units with carbon capture and sequestration (CCS) in order to comply with the Clean Power Plan's rate-based emission standards under an emission trading scheme...
  64. Boulos D, Shehabi Y, Moghaddas J, Birrell M, Choy A, Giang V, et al. Predictive value of quick Sepsis-Related Organ Failure Scores following sepsis-related Medical Emergency Team calls: a retrospective cohort study. Anaesth Intensive Care. 2017;45:688-694 pubmed
    ..aetiology in 970 MET calls for 646 patients with a mean age of 68 years and median Charlson Comorbidity score (CCS) of 3.0...
  65. Vestring S, Fernández Morales J, Méndez López I, C Musial D, G de Diego A, Padín J, et al. Tight mitochondrial control of calcium and exocytotic signals in chromaffin cells at embryonic life. Pflugers Arch. 2015;467:2589-601 pubmed publisher
    ..a relevant physiological function in the regulation of Ca(2+) and exocytotic signals in mature chromaffin cells (CCs) from various adult mammals...
  66. Kammerer B, Hung T, Baxter R, Teh S. Physiological effects of salinity on Delta Smelt, Hypomesus transpacificus. Fish Physiol Biochem. 2016;42:219-32 pubmed publisher
    ..Percent muscle water content (%) did not show significant changes. CCs showed increased NKA, cell size and apoptosis over time in SW, indicating that CCs turnover in DS...
  67. Asgar A, Lauck S, Ko D, Alqoofi F, Cohen E, Forsey A, et al. Quality of Care for Transcatheter Aortic Valve Implantation: Development of Canadian Cardiovascular Society Quality Indicators. Can J Cardiol. 2016;32:1038.e1-4 pubmed publisher
    ..As a part of the Canadian Cardiovascular Society (CCS) quality initiative, the TAVI Quality Indicator (QI) Working Group was established in 2014 to develop a set of ..
  68. Righetti L, Fenclova M, Dellafiora L, Hajslova J, Stranska Zachariasova M, Dall Asta C. High resolution-ion mobility mass spectrometry as an additional powerful tool for structural characterization of mycotoxin metabolites. Food Chem. 2018;245:768-774 pubmed publisher
    ..to demonstrate the successful use of the comparison between theoretical and experimental collision cross section (CCS) values to support the identification of isomeric forms...
  69. Khakinejad M, Ghassabi Kondalaji S, Tafreshian A, Valentine S. Comprehensive Gas-Phase Peptide Ion Structure Studies Using Ion Mobility Techniques: Part 2. Gas-Phase Hydrogen/Deuterium Exchange for Ion Population Estimation. J Am Soc Mass Spectrom. 2017;28:960-970 pubmed publisher
    Gas-phase hydrogen/deuterium exchange (HDX) using D2O reagent and collision cross-section (CCS) measurements are utilized to monitor the ion conformers of the model peptide acetyl-PAAAAKAAAAKAAAAKAAAAK...
  70. Ağralı S, Üçtuğ F, Türkmen B. An optimization model for carbon capture & storage/utilization vs. carbon trading: A case study of fossil-fired power plants in Turkey. J Environ Manage. 2018;215:305-315 pubmed publisher
    ..These plants need to choose between carbon capture and storage (CCS), carbon capture and utilization (CCU), or carbon trading in order to obey emissions limits enforced by the ..
  71. Ishida Y, Honda M, Kamibeppu K, Ozono S, Okamura J, Asami K, et al. Social outcomes and quality of life of childhood cancer survivors in Japan: a cross-sectional study on marriage, education, employment and health-related QOL (SF-36). Int J Hematol. 2011;93:633-644 pubmed publisher
    ..Questionnaires from 185 CCSs and 72 CCS's siblings were analyzed. There were no differences in educational attainment or annual income...
  72. Zhao R, Huang M, Banafea O, Zhao J, Cheng L, Zou K, et al. Cronkhite-Canada syndrome: a rare case report and literature review. BMC Gastroenterol. 2016;16:23 pubmed publisher
    Cronkhite-Canada Syndrome (CCS) is a rare non-inherited disease characterized by gastrointestinal polyposis and ectodermal abnormalities, the estimated incidence is about one per million...
  73. Kim Y, Oh S, Go S, Kang J, Park I, Song H, et al. The role of adjuvant therapy after R0 resection for patients with intrahepatic and perihilar cholangiocarcinomas. Cancer Chemother Pharmacol. 2017;79:99-106 pubmed publisher
    ..The aim of this study was to analyze the role of adjuvant therapy in R0-resected intrahepatic and perihilar CCs. We retrospectively reviewed the patients who underwent R0 resection for intrahepatic and perihilar CCs between ..
  74. Macirella R, Brunelli E. Morphofunctional Alterations in Zebrafish (Danio rerio) Gills after Exposure to Mercury Chloride. Int J Mol Sci. 2017;18: pubmed publisher
    ..The main morphological effects recorded in this work were represented by hyperplasia and ectopia of chloride cells (CCs), lamellar fusion, increased mucous secretion, alteration of pavement cells (PVCs), detachment of the secondary ..
  75. Sato T, Usui M, Konishi N, Kai A, Matsui H, Hanaki H, et al. Closely related methicillin-resistant Staphylococcus aureus isolates from retail meat, cows with mastitis, and humans in Japan. PLoS ONE. 2017;12:e0187319 pubmed publisher
    ..54 CA-MRSA were classified into 6 different CCs: CC1 (n = 14), CC5 (n = 7), CC8 (n = 29), CC45 (n = 1), CC89 (n = 1), CC509 (n = 1), and into 16 different spa ..
  76. Trovillion E, Schubert L, Dietz A. Iron Overload in Survivors of Childhood Cancer. J Pediatr Hematol Oncol. 2017;: pubmed publisher
    Patients transfused with packed red blood cells (PRBC), including childhood cancer survivors (CCS), experience complications. We describe iron overload (ferritin>500 ng/mL) prevalence and identify risk factors in CCS.
  77. Vecchione L, Gambino V, Raaijmakers J, Schlicker A, Fumagalli A, Russo M, et al. A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility. Cell. 2016;165:317-30 pubmed publisher
    BRAF(V600E) mutant colon cancers (CCs) have a characteristic gene expression signature that is also found in some tumors lacking this mutation. Collectively, they are referred to as "BRAF-like" tumors and represent some 20% of CCs...
  78. Ferretti E, Ponzoni M, Doglioni C, Pistoia V. IL-17 superfamily cytokines modulate normal germinal center B cell migration. J Leukoc Biol. 2016;100:913-918 pubmed
    ..enriched in proliferating centroblasts (CBs), and a light zone where CBs migrate and transform into centrocytes (CCs), a minority of which is selected to survive, undergoes Ig class-switch recombination, and differentiates into ..
  79. Meershoek A, van Dijk R, Verhage S, Hamming J, van den Bogaerdt A, Bogers A, et al. Histological evaluation disqualifies IMT and calcification scores as surrogates for grading coronary and aortic atherosclerosis. Int J Cardiol. 2016;224:328-334 pubmed publisher
    Carotid intimal media thickness (IMT) and coronary calcium scores (CCS) are thought to reflect atherosclerotic burden...
  80. Zhou Z, Tu J, Zhu Z. Advancing the large-scale CCS database for metabolomics and lipidomics at the machine-learning era. Curr Opin Chem Biol. 2018;42:34-41 pubmed publisher
    ..The collision cross-section (CCS) value derived from IM-MS is a valuable physiochemical property for the unambiguous identification of metabolites ..
  81. Nunley P, Mundis G, Fessler R, Park P, Zavatsky J, Uribe J, et al. Impact of case type, length of stay, institution type, and comorbidities on Medicare diagnosis-related group reimbursement for adult spinal deformity surgery. Neurosurg Focus. 2017;43:E11 pubmed publisher
    ..hospital type/location, number of operative levels, proper coding, length of stay, and complications/comorbidities (CCs) were analyzed for effects on reimbursement...
  82. Silahtaroglu A, Jensen L, Harboe T, Horn P, Bendixen C, Tommerup N, et al. Sequencing and mapping of the porcine CCS gene. Anim Genet. 2004;35:353-4 pubmed
  83. Braga D, Setti A, Lo Turco E, Cordeiro F, Cabral E, Cortezzi S, et al. Protein expression in human cumulus cells as an indicator of blastocyst formation and pregnancy success. J Assist Reprod Genet. 2016;33:1571-1583 pubmed
    ..the present study was to implement a technique for protein extraction and identification in human cumulus cells (CCs)...
  84. Fukuoka M, Tokuda E, Nakagome K, Wu Z, Nagano I, Furukawa Y. An essential role of N-terminal domain of copper chaperone in the enzymatic activation of Cu/Zn-superoxide dismutase. J Inorg Biochem. 2017;175:208-216 pubmed publisher
    ..In a eukaryotic cell, a copper chaperone for SOD1 (CCS) has been known to supply a copper ion and also introduce the disulfide bond into SOD1; however, a mechanism ..
  85. Maus V, Behme D, Borggrefe J, Kabbasch C, Seker F, Hüseyin C, et al. Carotid Artery Stenosis Contralateral to Acute Tandem Occlusion: An Independent Predictor of Poor Clinical Outcome after Mechanical Thrombectomy with Concomitant Carotid Artery Stenting. Cerebrovasc Dis. 2017;45:10-17 pubmed publisher
    ..The impact of concomitant contralateral carotid stenosis (CCS) upon outcome remains unclear in this stroke subtype.
  86. Suazo M, Olivares F, Mendez M, Pulgar R, Prohaska J, Arredondo M, et al. CCS and SOD1 mRNA are reduced after copper supplementation in peripheral mononuclear cells of individuals with high serum ceruloplasmin concentration. J Nutr Biochem. 2008;19:269-74 pubmed
    ..prion (PrP), amyloid precursor-like protein 2 (APLP2), Cu/Zn superoxide dismutase (SOD1) and its copper chaperone (CCS) in peripheral mononuclear cells (PMNCs) from healthy adults representing the 5% highest and lowest extremes in the ..
  87. Wang L, Ge Y, Kang Y. Featured Article: Effect of copper on nuclear translocation of copper chaperone for superoxide dismutase-1. Exp Biol Med (Maywood). 2016;241:1483-8 pubmed publisher
    b>Copper chaperone for superoxide dismutase-1 (CCS-1), facilitating copper insertion into superoxide dismutase 1 (SOD-1), is present in the nucleus. However, it is unknown how CCS-1 is translocated to the nucleus...
  88. Park B, Kim M, Cha C, Lee Y, Kim K. High Calcium-Magnesium Ratio in Hair Is Associated with Coronary Artery Calcification in Middle-Aged and Elderly Individuals. Biol Trace Elem Res. 2017;179:52-58 pubmed publisher
    ..analysis, we examined the associations between calcium-magnesium ratio in hair and the coronary calcium score (CCS) in 216 Koreans aged 40 years and above (122 men and 94 women)...
  89. Karmouch J, Zhou Q, Miyake C, Lombardi R, Kretzschmar K, Bannier Hélaouët M, et al. Distinct Cellular Basis for Early Cardiac Arrhythmias, the Cardinal Manifestation of Arrhythmogenic Cardiomyopathy, and the Skin Phenotype of Cardiocutaneous Syndromes. Circ Res. 2017;121:1346-1359 pubmed publisher
    ..The findings offer a cellular basis for early cardiac arrhythmias in patients with arrhythmogenic cardiomyopathy and cardiocutaneous syndromes. ..
  90. Lamb A, Wernimont A, Pufahl R, O Halloran T, Rosenzweig A. Crystal structure of the second domain of the human copper chaperone for superoxide dismutase. Biochemistry. 2000;39:1589-95 pubmed
    The human copper chaperone for superoxide dismutase (hCCS) delivers the essential copper ion cofactor to copper,zinc superoxide dismutase (SOD1), a key enzyme in antioxidant defense...
  91. Crooks R, Lathbridge A, Panek A, Mason J. Computational Prediction and Design for Creating Iteratively Larger Heterospecific Coiled Coil Sets. Biochemistry. 2017;56:1573-1584 pubmed publisher
    ..The expanded data set has resulted in emerging sequence context rules for otherwise energetically equivalent CCs; for example, introducing intrahelical electrostatic charge blocks generated increased stability for designed CCs ..
  92. Zhao J, Koo O, Pan D, Wu Y, Morkhade D, Rana S, et al. The Impact of Disintegrant Type, Surfactant, and API Properties on the Processability and Performance of Roller Compacted Formulations of Acetaminophen and Aspirin. AAPS J. 2017;19:1387-1395 pubmed publisher
    ..In this study, three common disintegrants, croscarmellose sodium (CCS), crospovidone (xPVP), and sodium starch glycolate (SSG) as well as the surfactant sodium lauryl sulfate (SLS) were ..