GCG

Summary

Gene Symbol: GCG
Description: glucagon
Alias: glucagon
Species: cow
Products:     GCG

Top Publications

  1. Drucker D. Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. Mol Endocrinol. 2003;17:161-71 pubmed publisher
    ..The glucagon-like peptides, GLP-1 and GLP-2 are prototype peptide hormones released from gut endocrine cells in response to ..
  2. Lopez L, Frazier M, Su C, Kumar A, Saunders G. Mammalian pancreatic preproglucagon contains three glucagon-related peptides. Proc Natl Acad Sci U S A. 1983;80:5485-9 pubmed
    ..DNA oligomers constructed to correspond to the six carboxyl-terminal amino acids (residues 24-29) of mature glucagon. Restriction mapping of six of these clones suggested that they represented a single mRNA species...
  3. Braun W, Wider G, Lee K, Wuthrich K. Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance. J Mol Biol. 1983;169:921-48 pubmed
    A determination of the spatial structure of the polypeptide hormone glucagon bound to perdeuterated dodecylphosphocholine micelles is described...
  4. Segner H, Blair J, Wirtz G, Miller M. Cultured trout liver cells: utilization of substrates and response to hormones. In Vitro Cell Dev Biol Anim. 1994;30A:306-11 pubmed
    ..and glycerol for glucose and lactate formation; b) the effects of the pancreatic hormones insulin and glucagon on cellular glucose formation, lactate formation, and fatty acid synthesis; and c) the effects of insulin and ..
  5. Kieffer T, Habener J. The glucagon-like peptides. Endocr Rev. 1999;20:876-913 pubmed publisher
  6. Taylor Edwards C, Burrin D, Matthews J, McLeod K, Holst J, Harmon D. Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake. Domest Anim Endocrinol. 2010;39:181-93 pubmed publisher
    b>Glucagon-like peptide-2 (GLP-2) is a potent trophic gut hormone, yet its function in ruminants is relatively unknown...
  7. Bromer W, Boucher M, Kofenberger J. Amino acid sequence of bovine glucagon. J Biol Chem. 1971;246:2822-7 pubmed
  8. . Glucagon-like Peptide 2. Trends Endocrinol Metab. 1999;10:153-156 pubmed
    b>Glucagon-like peptide 2 (GLP-2) is secreted in a nutrient-dependent manner from enteroendocrine cells throughout the gastrointestinal tract and is trophic to the intestinal epithelial mucosa...

Detail Information

Publications8

  1. Drucker D. Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. Mol Endocrinol. 2003;17:161-71 pubmed publisher
    ..The glucagon-like peptides, GLP-1 and GLP-2 are prototype peptide hormones released from gut endocrine cells in response to ..
  2. Lopez L, Frazier M, Su C, Kumar A, Saunders G. Mammalian pancreatic preproglucagon contains three glucagon-related peptides. Proc Natl Acad Sci U S A. 1983;80:5485-9 pubmed
    ..DNA oligomers constructed to correspond to the six carboxyl-terminal amino acids (residues 24-29) of mature glucagon. Restriction mapping of six of these clones suggested that they represented a single mRNA species...
  3. Braun W, Wider G, Lee K, Wuthrich K. Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance. J Mol Biol. 1983;169:921-48 pubmed
    A determination of the spatial structure of the polypeptide hormone glucagon bound to perdeuterated dodecylphosphocholine micelles is described...
  4. Segner H, Blair J, Wirtz G, Miller M. Cultured trout liver cells: utilization of substrates and response to hormones. In Vitro Cell Dev Biol Anim. 1994;30A:306-11 pubmed
    ..and glycerol for glucose and lactate formation; b) the effects of the pancreatic hormones insulin and glucagon on cellular glucose formation, lactate formation, and fatty acid synthesis; and c) the effects of insulin and ..
  5. Kieffer T, Habener J. The glucagon-like peptides. Endocr Rev. 1999;20:876-913 pubmed publisher
  6. Taylor Edwards C, Burrin D, Matthews J, McLeod K, Holst J, Harmon D. Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake. Domest Anim Endocrinol. 2010;39:181-93 pubmed publisher
    b>Glucagon-like peptide-2 (GLP-2) is a potent trophic gut hormone, yet its function in ruminants is relatively unknown...
  7. Bromer W, Boucher M, Kofenberger J. Amino acid sequence of bovine glucagon. J Biol Chem. 1971;246:2822-7 pubmed
  8. . Glucagon-like Peptide 2. Trends Endocrinol Metab. 1999;10:153-156 pubmed
    b>Glucagon-like peptide 2 (GLP-2) is secreted in a nutrient-dependent manner from enteroendocrine cells throughout the gastrointestinal tract and is trophic to the intestinal epithelial mucosa...