E Di Cera
Affiliation: Washington University School of Medicine
- Di Cera E. Thrombin: a paradigm for enzymes allosterically activated by monovalent cations. C R Biol. 2004;327:1065-76 pubmed..Here we review the molecular basis of thrombin allostery as recently emerged from mutagenesis and structural studies. The role of Na+ in blood coagulation and the evolution of serine proteases are also discussed...
- Di Cera E. A structural perspective on enzymes activated by monovalent cations. J Biol Chem. 2006;281:1305-8 pubmed..That enables a simple classification of these functionally diverse enzymes and reveals unanticipated connections with ion transporters...