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- Sierra A, Subbotina E, Zhu Z, Gao Z, Koganti S, Coetzee W, et al. Disruption of ATP-sensitive potassium channel function in skeletal muscles promotes production and secretion of musclin. Biochem Biophys Res Commun. 2016;471:129-34 pubmed publisher..Understanding such mechanisms is an important step toward designing interventions to manage metabolic disorders including those related to excess body fat and associated co-morbidities. ..