Affiliation: University of Southern California
Krainock M, Toubat O, Danopoulos S, Beckham A, Warburton D, Kim R. Epicardial Epithelial-to-Mesenchymal Transition in Heart Development and Disease. J Clin Med. 2016;5: pubmed publisher
..This review will focus on the induction and regulation of epicardial EMT, as it pertains to both cardiogenesis and the response of the myocardium to injury. ..
Bower D, Lee H, Lansford R, Zinn K, Warburton D, Fraser S, et al
. Airway branching has conserved needs for local parasympathetic innervation but not neurotransmission. BMC Biol. 2014;12:92 pubmed publisher
..Our novel, targeted laser ablation technique permitted the local function of parasympathetic innervation to be distinguished from neurotransmission. ..
Zhang W, Menke D, Jiang M, Chen H, Warburton D, Turcatel G, et al
. Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer. BMC Biol. 2013;11:111 pubmed publisher
Warburton D, Zhao J, Berberich M, Bernfield M. Molecular embryology of the lung: then, now, and in the future. Am J Physiol. 1999;276:L697-704 pubmed
..A scientific rationale for developing new therapeutic approaches to urgent questions of human pulmonary health such as bronchopulmonary dysplasia is beginning to emerge from work in this field. ..
Warburton D, Shi W, Xu B. TGF-?-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development?. Am J Physiol Lung Cell Mol Physiol. 2013;304:L83-5 pubmed publisher
Turcatel G, Rubin N, Menke D, Martin G, Shi W, Warburton D. Lung mesenchymal expression of Sox9 plays a critical role in tracheal development. BMC Biol. 2013;11:117 pubmed publisher
..Sox9 is expressed in both distal lung epithelium and proximal lung mesenchyme. Here, we investigated the effect of lung mesenchyme-specific inducible deletion of Sox9 during murine lung development...
Buckley S, Shi W, Xu W, Frey M, Moats R, Pardo A, et al
. Increased alveolar soluble annexin V promotes lung inflammation and fibrosis. Eur Respir J. 2015;46:1417-29 pubmed publisher
..Chronically increased alveolar annexin V levels, as reflected in increased IPF BALF levels, may contribute to the progression of IPF by inducing the release of pro-fibrotic mediators. ..
Gamba L, Amin Javaheri A, Kim J, Warburton D, Lien C. Collagenolytic Activity Is Associated with Scar Resolution in Zebrafish Hearts after Cryoinjury. J Cardiovasc Dev Dis. 2017;4: pubmed publisher
..These findings suggest that collagenolytic activity may be key to how the zebrafish heart resolves its scar; however, it is not sufficient in mouse hearts that lack efficient myocardial regeneration. ..