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Steven A Soper
Affiliation: University of North Carolina
Jackson J, Taylor J, Witek M, Hunsucker S, Waugh J, Fedoriw Y, et al. Microfluidics for the detection of minimal residual disease in acute myeloid leukemia patients using circulating leukemic cells selected from blood. Analyst. 2016;141:640-51 pubmed publisher
..Earlier detection of MRD in AML post-SCT enabled by peripheral blood sampling using the microfluidic assay we report herein can influence curative clinical decisions for AML patients. ..
Nair S, Witek M, Jackson J, Lindell M, Hunsucker S, Sapp T, et al. Enzymatic cleavage of uracil-containing single-stranded DNA linkers for the efficient release of affinity-selected circulating tumor cells. Chem Commun (Camb). 2015;51:3266-9 pubmed publisher
..The strategy utilizes single-stranded DNAs that link a capture antibody to the surfaces of a CTC selection device. The DNA linkers contain a uracil residue that can be cleaved. ..