Patrick L Sinn
Affiliation: University of Iowa
- Singh B, Hornick A, Krishnamurthy S, Locke A, Mendoza C, Mateo M, et al. The Nectin-4/Afadin Protein Complex and Intercellular Membrane Pores Contribute to Rapid Spread of Measles Virus in Primary Human Airway Epithelia. J Virol. 2015;89:7089-96 pubmed publisher..Rapid homogenization of cytoplasmic contents in epithelial infectious centers may favor rapid spread and contribute to the extremely contagious nature of measles. ..
- Singh B, Li N, Mark A, Mateo M, Cattaneo R, Sinn P. Cell-to-Cell Contact and Nectin-4 Govern Spread of Measles Virus from Primary Human Myeloid Cells to Primary Human Airway Epithelial Cells. J Virol. 2016;90:6808-17 pubmed publisher..Furthermore, cell-to-cell contact is an important component of successful MeV transfer. Our studies elucidate a mechanism by which the most contagious human respiratory virus is delivered to the airway epithelium. ..