Genomes and Genes
Affiliation: University of Iowa
- Philibert R, Beach S, Gunter T, Todorov A, Brody G, Vijayendran M, et al. The relationship of deiodinase 1 genotype and thyroid function to lifetime history of major depression in three independent populations. Am J Med Genet B Neuropsychiatr Genet. 2011;156B:593-9 pubmed publisher..We conclude that genetic variation influencing thyroid function is a risk factor for MD. Given the evidence from prior studies, further investigations of role of HPT variation in etiology and treatment of MD are indicated. ..
- Philibert R, Nelson J, Sandhu H, Crowe R, Coryell W. Association of an exonic LDHA polymorphism with altered respiratory response in probands at high risk for panic disorder. Am J Med Genet B Neuropsychiatr Genet. 2003;117B:11-7 pubmed
- Philibert R, Gunter T, Beach S, Brody G, Madan A. MAOA methylation is associated with nicotine and alcohol dependence in women. Am J Med Genet B Neuropsychiatr Genet. 2008;147B:565-70 pubmed publisher..10). We conclude that methylation of MAOA may play a significant role in common psychiatric illness and that further examination of epigenetic processes at this locus is in order. ..
- Philibert R, Beach S, Brody G. Demethylation of the aryl hydrocarbon receptor repressor as a biomarker for nascent smokers. Epigenetics. 2012;7:1331-8 pubmed publisher..We also suggest that the AHRR/AHR pathway may be functional in the response of peripheral white blood cells to tobacco smoke exposure. ..