John Farmer

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. doi request reprint The Vytorin on Carotid-Media Thickness and Overall Arterial Rigidity (VYCTOR) study
    John Farmer
    Baylor College of Medicine, Houston, TX 77030, USA
    Expert Rev Cardiovasc Ther 7:1057-60. 2009
  2. ncbi request reprint Pleiotropic effects of statins
    J A Farmer
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Atheroscler Rep 2:208-17. 2000
  3. ncbi request reprint Hypertension and the metabolic syndrome
    John A Farmer
    Baylor College of Medicine, Section of Cardiology, One Baylor Plaza, MS 523D, Houston, TX 77030, USA
    Curr Cardiol Rep 6:427-33. 2004
  4. ncbi request reprint Diabetic dyslipidemia and atherosclerosis: evidence from clinical trials
    John A Farmer
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Room 525 D, Houston, TX 77030, USA
    Curr Atheroscler Rep 9:162-8. 2007
  5. ncbi request reprint Statins and myotoxicity
    John A Farmer
    Baylor College of Medicine, One Baylor Plaza, Room 525D, Houston, TX 77030, USA
    Curr Atheroscler Rep 5:96-100. 2003
  6. ncbi request reprint Diabetic dyslipidemia and atherosclerosis: evidence from clinical trials
    John A Farmer
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Room 525 D, Houston, TX 77030, USA
    Curr Diab Rep 8:71-7. 2008
  7. ncbi request reprint Nicotinic acid: a new look at an old drug
    John A Farmer
    Department of Cardiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Atheroscler Rep 11:87-92. 2009
  8. doi request reprint The sympathetic nervous system and pathophysiology of congestive heart failure
    John Farmer
    Department of Medicine Cardiology, Baylor College of Medicine, Houston, TX 77030, USA
    Postgrad Med 118:6-11. 2005
  9. ncbi request reprint Atherosclerosis and inflammation
    John A Farmer
    Section of Cardiology, Baylor College of Medicine, Ben Taub General Hospital, One Baylor Plaza, Room 525D, Houston, TX 77030, USA
    Curr Atheroscler Rep 4:92-8. 2002
  10. ncbi request reprint The renin angiotensin system as a risk factor for coronary artery disease
    J A Farmer
    Section of Cardiology, Ben Taub General Hospital and Baylor College of Medicine, 6550 Fannin, Houston, TX 77030, USA
    Curr Atheroscler Rep 3:117-24. 2001

Collaborators

Detail Information

Publications30

  1. doi request reprint The Vytorin on Carotid-Media Thickness and Overall Arterial Rigidity (VYCTOR) study
    John Farmer
    Baylor College of Medicine, Houston, TX 77030, USA
    Expert Rev Cardiovasc Ther 7:1057-60. 2009
    ..The VYCTOR study did not reveal significant differences in C-reactive protein, HDL, triglycerides, blood pressure or BMI between groups...
  2. ncbi request reprint Pleiotropic effects of statins
    J A Farmer
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Atheroscler Rep 2:208-17. 2000
    ..This review will focus on the potential beneficial effects of statin therapy on a number of the pleiotropic effects of statins and the potential role that these activities play in the reduction of risk for ischemic events...
  3. ncbi request reprint Hypertension and the metabolic syndrome
    John A Farmer
    Baylor College of Medicine, Section of Cardiology, One Baylor Plaza, MS 523D, Houston, TX 77030, USA
    Curr Cardiol Rep 6:427-33. 2004
    ....
  4. ncbi request reprint Diabetic dyslipidemia and atherosclerosis: evidence from clinical trials
    John A Farmer
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Room 525 D, Houston, TX 77030, USA
    Curr Atheroscler Rep 9:162-8. 2007
    ..However, the robust bulk of clinical data obtained from prospective statin studies is lacking for the fibric acid derivatives, and the results of the major trials are equivocal...
  5. ncbi request reprint Statins and myotoxicity
    John A Farmer
    Baylor College of Medicine, One Baylor Plaza, Room 525D, Houston, TX 77030, USA
    Curr Atheroscler Rep 5:96-100. 2003
    ....
  6. ncbi request reprint Diabetic dyslipidemia and atherosclerosis: evidence from clinical trials
    John A Farmer
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Room 525 D, Houston, TX 77030, USA
    Curr Diab Rep 8:71-7. 2008
    ..However, the robust bulk of clinical data obtained from prospective statin studies is lacking for the fibric acid derivatives, and the results of the major trials are equivocal...
  7. ncbi request reprint Nicotinic acid: a new look at an old drug
    John A Farmer
    Department of Cardiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Atheroscler Rep 11:87-92. 2009
    ..Clinical trials utilizing clinical or angiographic end points demonstrated efficacy for the use of nicotinic acid in monotherapy or in combination with bile acid resins or statins...
  8. doi request reprint The sympathetic nervous system and pathophysiology of congestive heart failure
    John Farmer
    Department of Medicine Cardiology, Baylor College of Medicine, Houston, TX 77030, USA
    Postgrad Med 118:6-11. 2005
    ..This article will discuss of the role of the sympathetic nervous system in congestive heart failure and the use of beta-blockade as a means to improve both hemodynamics and progression of disease...
  9. ncbi request reprint Atherosclerosis and inflammation
    John A Farmer
    Section of Cardiology, Baylor College of Medicine, Ben Taub General Hospital, One Baylor Plaza, Room 525D, Houston, TX 77030, USA
    Curr Atheroscler Rep 4:92-8. 2002
    ..This review centers on inflammation as a potential pathogenetic factor in atherosclerosis and the role that clinical markers may play in the identification of patients at risk...
  10. ncbi request reprint The renin angiotensin system as a risk factor for coronary artery disease
    J A Farmer
    Section of Cardiology, Ben Taub General Hospital and Baylor College of Medicine, 6550 Fannin, Houston, TX 77030, USA
    Curr Atheroscler Rep 3:117-24. 2001
    ....
  11. ncbi request reprint Platelet inhibition with tirofiban early during percutaneous coronary intervention: dosing revisited
    Nasser Lakkis
    Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, Texas, USA
    Catheter Cardiovasc Interv 56:474-7. 2002
    ..Dose adjustment may be needed to maximize platelet inhibition early during PCI...
  12. ncbi request reprint The Heart Protection Study: expanding the boundaries for high-risk coronary disease prevention
    John A Farmer
    Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Am J Cardiol 92:3i-9i. 2003
    ..These data are likely to have an important influence on the future of cardiovascular disease prevention...
  13. ncbi request reprint The role of inflammation in the pathogenesis of heart failure
    Kevin A Lisman
    Department of Medicine, Section of Cardiology, Baylor College of Medicine, 6550 Fannin, Suite 1901, Houston, TX 77030, USA
    Curr Cardiol Rep 4:200-5. 2002
    ..As a result, new therapies will develop that block, modify, or prevent these inflammatory changes, and supplement our armamentarium for providing better and longer lives for patients...
  14. doi request reprint High-density lipoprotein and atherosclerosis: the role of antioxidant activity
    Salman Bandeali
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Curr Atheroscler Rep 14:101-7. 2012
    ..Increasing amounts of clinical and experimental data have shown that HDL cholesterol has significant antioxidant effect that may significantly contribute to protection from atherosclerosis...
  15. ncbi request reprint Simvastatin decreases myocardial tumor necrosis factor alpha content in heart transplant recipients
    Cynthia K Wallace
    Baylor College of Medicine, 6550 Fannin, Houston, Texas 77030, USA
    J Heart Lung Transplant 24:46-51. 2005
    ..We studied the effects of simvastatin treatment on myocardial tumor necrosis factor alpha (TNF-alpha) expression; TNF-alpha is a potent pro-inflammatory cytokine associated with hypertrophy and fibrosis in heart transplant recipients...
  16. ncbi request reprint Optimal low-density lipoprotein levels: evidence from epidemiology and clinical trials
    Josh Todd
    Section of Cardiology, Baylor College of Medicine, Houston, TX 77030, USA
    Curr Atheroscler Rep 8:157-62. 2006
    ....
  17. doi request reprint Statins as adjunctive therapy in the management of hypertension
    Joshua Liao
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Room 525D, Houston, TX 77030, USA
    Curr Atheroscler Rep 12:349-54. 2010
    ..This review examines the observational relationship between hypertension and dyslipidemia, the potential mechanisms by which statin therapy may lower blood pressure, and selected clinical trial data...
  18. ncbi request reprint Obesity and inflammation: a new look at an old problem
    Sachin Mehta
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Room 525 D, Houston, TX 77030, USA
    Curr Atheroscler Rep 9:134-8. 2007
    ..The concept that obesity represents an inflammatory state has gained credence over the past decade and has provided insights into the mechanisms of atherosclerosis and risk factor interaction...
  19. ncbi request reprint Raising high-density lipoprotein cholesterol: innovative strategies against an old adversary
    Dhruv Kazi
    Department of Internal Medicine, Baylor College of Medicine, One Baylor Plaza, MS 523D, Houston, TX 77030, USA
    Curr Atheroscler Rep 7:88-94. 2005
    ..The mechanisms and clinical implications of these interventions are discussed here...
  20. doi request reprint Dysfunctional high-density lipoprotein and atherosclerosis
    Shawn Ragbir
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Room 525D, Houston, TX 77030, USA
    Curr Atheroscler Rep 12:343-8. 2010
    ..Dysfunctional HDL may be returned to normal by diet, exercise, degree of fat intake, and pharmacologic approaches. Orally active mimetic proteins are in development and have shown clinical promise...
  21. ncbi request reprint The role of tumor necrosis factor alpha blockade in the treatment of congestive heart failure
    Kevin A Lisman
    The DeBakey Heart Center at The Methodist Hospital, Houston, TX, USA
    Congest Heart Fail 8:275-9. 2002
    ..The explanation of those findings are not clear; however, based on the strength of the experimental evidence one can conclude that perhaps other nonspecific approaches to manipulate the immune system may be of benefit...
  22. ncbi request reprint The role of statin therapy in the management of cardiomyopathies
    Kumudha Ramasubbu
    Department of Cardiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Atheroscler Rep 11:118-23. 2009
    ..This review outlines the proposed biologic effects of statins in heart failure syndrome and clinical evidence of statin use in heart failure patients...
  23. ncbi request reprint Role of insulin signaling in maintaining energy homeostasis
    Morali D Sharma
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Baylor College of Medicine, Houston, Texas 77030, USA
    Endocr Pract 14:373-80. 2008
    ..To examine the role that insulin signaling plays in modulating metabolic functions involving both peripheral and hypothalamic systems...
  24. ncbi request reprint Adjunctive interventions in myocardial infarction: the role of statin therapy
    Peter H Jones
    Section of Cardiology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Room 525D, Houston, TX 77030, USA
    Curr Atheroscler Rep 10:142-8. 2008
    ....
  25. ncbi request reprint Benefits of atorvastatin in cholesterol lowering
    John A Farmer
    Curr Atheroscler Rep 5:94-5. 2003
  26. ncbi request reprint Benefits of simvastin in cholesterol lowering
    John A Farmer
    Curr Atheroscler Rep 5:93-4. 2003
  27. ncbi request reprint Reducing the risk for stroke in patients with myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy
    Antonio M Gotto
    Circulation 106:1595-8. 2002
  28. ncbi request reprint Rationale for aggressive lipid lowering: evidence from clinical trials
    John A Farmer
    Expert Rev Cardiovasc Ther 2:305-9. 2004
  29. ncbi request reprint Drug insight: the role of statins in combination with ezetimibe to lower LDL cholesterol
    Antonio M Gotto
    Weill Medical College of Cornell University, 445 East 69th Street, OH205, New York, NY 10021, USA
    Nat Clin Pract Cardiovasc Med 3:664-72. 2006
    ..In this Review we consider the rationale for combination therapy in the context of achieving LDL-cholesterol goals...
  30. ncbi request reprint Reversal of atherosclerosis with aggressive lipid lowering
    John A Farmer
    Curr Atheroscler Rep 7:86-7. 2005