John Black

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Associations between serotonin transporter gene polymorphisms and heat pain perception in adults with chronic pain
    W Michael Hooten
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    BMC Med Genet 14:78. 2013
  2. pmc Frequency of undetected CYP2D6 hybrid genes in clinical samples: impact on phenotype prediction
    John Logan Black
    Department of Laboratory Medicine and Pathology, Mayo Clinic 200 1st Street SW, Rochester, Minnesota, NM 55902, USA
    Drug Metab Dispos 40:111-9. 2012
  3. ncbi Correlation of CYP2B6, CYP2C19, ABCC4 and SOD2 genotype with outcomes in allogeneic blood and marrow transplant patients
    John L Black
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Leuk Res 36:59-66. 2012
  4. ncbi Serologic survey of adult patients with obsessive-compulsive disorder for neuron-specific and other autoantibodies
    J L Black
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Psychiatry Res 81:371-80. 1998
  5. ncbi The impact of CYP allelic variation on antidepressant metabolism: a review
    John L Black
    Psychogenomics Laboratory, Department of Pyschiatry and Psychology, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, Minnesota 55905, USA
    Expert Opin Drug Metab Toxicol 3:21-31. 2007
  6. ncbi Narcolepsy: a review of evidence for autoimmune diathesis
    John Logan Black
    Psychogenomic Laboratory, Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Int Rev Psychiatry 17:461-9. 2005
  7. ncbi Analysis of hypocretin (orexin) antibodies in patients with narcolepsy
    John L Black
    Psychogenomics Laboratory, Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Sleep 28:427-31. 2005
  8. ncbi Studies of humoral immunity to preprohypocretin in human leukocyte antigen DQB1*0602-positive narcoleptic subjects with cataplexy
    John L Black
    Psychogenomics Laboratory, Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Biol Psychiatry 58:504-9. 2005
  9. ncbi The voltage-gated calcium channel gamma subunits: a review of the literature
    John Logan Black
    Section of Medical Psychiatry, Mayo Medical School, Mayo Clinic and Foundation, 200 1st Street Southwest, Rochester, Minnesota 55905, USA
    J Bioenerg Biomembr 35:649-60. 2003
  10. ncbi Voltage-gated calcium channel gamma 2 subunit gene is not deleted in velo-cardio-facial syndrome
    J L Black
    Department of Psychiatry and Psychology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Mol Psychiatry 6:461-4. 2001

Research Grants

Collaborators

Detail Information

Publications25

  1. pmc Associations between serotonin transporter gene polymorphisms and heat pain perception in adults with chronic pain
    W Michael Hooten
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    BMC Med Genet 14:78. 2013
    ..The primary aim of this study was to investigate the associations between heat pain (HP) perception and the triallelic 5-HTTLPR in a large cohort of adults with chronic pain...
  2. pmc Frequency of undetected CYP2D6 hybrid genes in clinical samples: impact on phenotype prediction
    John Logan Black
    Department of Laboratory Medicine and Pathology, Mayo Clinic 200 1st Street SW, Rochester, Minnesota, NM 55902, USA
    Drug Metab Dispos 40:111-9. 2012
    ..Four novel genes were identified (CYP2D6*13A1 variants 1 and 2, CYP2D6*13G1, and CYP2D6*13G2), and two novel hybrid tandem structures consisting of CYP2D6*13B + *68×2 + *4-like and CYP2D6*13A1 variant 2 + *1×N were observed...
  3. ncbi Correlation of CYP2B6, CYP2C19, ABCC4 and SOD2 genotype with outcomes in allogeneic blood and marrow transplant patients
    John L Black
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Leuk Res 36:59-66. 2012
    ....
  4. ncbi Serologic survey of adult patients with obsessive-compulsive disorder for neuron-specific and other autoantibodies
    J L Black
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Psychiatry Res 81:371-80. 1998
    ..Although most of our subjects had onset of OCD before 19 years of age (N=8) or before puberty (N=4), the study revealed no humoral evidence of autoimmunity involving the neuron-, organ-, and non-organ-specific antibodies that we assayed...
  5. ncbi The impact of CYP allelic variation on antidepressant metabolism: a review
    John L Black
    Psychogenomics Laboratory, Department of Pyschiatry and Psychology, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, Minnesota 55905, USA
    Expert Opin Drug Metab Toxicol 3:21-31. 2007
    ..The literature on the impact of CYP polymorphisms on antidepressant metabolism are also reviewed...
  6. ncbi Narcolepsy: a review of evidence for autoimmune diathesis
    John Logan Black
    Psychogenomic Laboratory, Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Int Rev Psychiatry 17:461-9. 2005
    ..Future research must focus on elucidation of immune markers and early ameliorative treatments for narcolepsy...
  7. ncbi Analysis of hypocretin (orexin) antibodies in patients with narcolepsy
    John L Black
    Psychogenomics Laboratory, Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Sleep 28:427-31. 2005
    ..We tested the hypothesis that patients with narcolepsy have serum antibodies specific for preprohypocretin and its derivatives...
  8. ncbi Studies of humoral immunity to preprohypocretin in human leukocyte antigen DQB1*0602-positive narcoleptic subjects with cataplexy
    John L Black
    Psychogenomics Laboratory, Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Biol Psychiatry 58:504-9. 2005
    ..We tested the hypothesis that DQB1*0602-positive narcoleptic subjects with cataplexy have immunoglobulin (Ig)G reactive to human preprohypocretin and its cleavage products...
  9. ncbi The voltage-gated calcium channel gamma subunits: a review of the literature
    John Logan Black
    Section of Medical Psychiatry, Mayo Medical School, Mayo Clinic and Foundation, 200 1st Street Southwest, Rochester, Minnesota 55905, USA
    J Bioenerg Biomembr 35:649-60. 2003
    ..This article reviews the discovery, cellular localization, tissue distribution, and function of the eight members of the Cacng family...
  10. ncbi Voltage-gated calcium channel gamma 2 subunit gene is not deleted in velo-cardio-facial syndrome
    J L Black
    Department of Psychiatry and Psychology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Mol Psychiatry 6:461-4. 2001
    ..The location of the gamma 2 subunit gene at 22q13.1 was confirmed by FISH in all cases. This study did not show a deletion of the gamma 2 subunit gene as a distinguishing feature of our patient with VCFS and schizophrenia...
  11. pmc CYP2C19 variation and citalopram response
    David A Mrazek
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pharmacogenet Genomics 21:1-9. 2011
    ..Citalopram is metabolized by three CYP enzymes. CYP2C19 and CYP3A4 play a primary role in citalopram metabolism, whereas CYP2D6 plays a secondary role...
  12. ncbi Interaction of SLC6A4 and DRD2 polymorphisms is associated with a history of delirium tremens
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Addict Biol 15:23-34. 2010
    ..This study provides the first evidence to implicate the interaction between serotonin and dopamine neurotransmission in the etiology of DT. Replication is necessary to verify this potentially important finding...
  13. ncbi Serotonin transporter gene status and electroconvulsive therapy outcomes: a retrospective analysis of 83 patients
    Keith G Rasmussen
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Clin Psychiatry 70:92-4. 2009
    ..Carrier status for the long allele has been associated with a better response to serotonin reuptake inhibitor antidepressant medications in most studies...
  14. pmc Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Alcohol Clin Exp Res 33:712-21. 2009
    ..Mpdz gene variations are known contributors of acute alcohol withdrawal severity and seizures in mice...
  15. ncbi Cytochrome P450 2D6 genotype variation and venlafaxine dosage
    Donald E McAlpine
    Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Mayo Clin Proc 82:1065-8. 2007
    ....
  16. ncbi Frequency of left ventricular dysfunction after electroconvulsive therapy
    Robert B McCully
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Cardiol 91:1147-50. 2003
  17. ncbi Patterns of psychotropic medication use among patients with severe depression referred for electroconvulsive therapy: data from the Consortium for Research on Electroconvulsive Therapy
    Keith G Rasmussen
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    J ECT 22:116-23. 2006
    ..Use of hypnotic agents and anticonvulsants was common. In conclusion, patients with severe depression referred for ECT with a unipolar depressive episode have high rates of psychotropic usage, much of which is inadequate...
  18. ncbi Obsessive compulsive disorder treatment in patients with Down syndrome: a case series
    Bruce Sutor
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 5905, USA
    Downs Syndr Res Pract 10:1-3. 2006
    ..None of the patients experienced significant side effects. This small case series supports the use of these medications in the treatment of co-morbid obsessive compulsive disorder in patients with Down syndrome...
  19. ncbi Relationship between FKBP5 polymorphisms and depression symptoms among kidney transplant recipients
    Gen Shinozaki
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Depress Anxiety 28:1111-8. 2011
    ....
  20. pmc CYP2D6: novel genomic structures and alleles
    Whitney E Kramer
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA
    Pharmacogenet Genomics 19:813-22. 2009
    ..The objective of this study was to discover the genomic structure of CYP2D6 recombinants that interfere with clinical genotyping platforms that are available today...
  21. ncbi Assessing attitudes about genetic testing as a component of continuing medical education
    Michael Mrazek
    Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Acad Psychiatry 31:447-51. 2007
    ..To investigate the attitudes among mental health professionals regarding the use of genetic testing...
  22. pmc Coprescription of tamoxifen and medications that inhibit CYP2D6
    Kostandinos Sideras
    Department of Oncology, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA
    J Clin Oncol 28:2768-76. 2010
    ....
  23. ncbi Primer on medical genomics. Part VI: Genomics and molecular genetics in clinical practice
    Stephen M Ansell
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 78:307-17. 2003
    ....
  24. ncbi Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*0602
    John Logan Black
    Department of Psychiatry, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Sleep 25:719-23. 2002
    ....
  25. pmc Narcolepsy: immunological aspects
    Sebastiaan Overeem
    Department of Neurology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Sleep Med Rev 12:95-107. 2008
    ..So far however, studies focusing on general markers of (auto)immune activation, as well as humoral immunity against the hypocretin system have not yielded consistent results supporting this hypothesis...

Research Grants1

  1. Hypocretin System Immune Diathesis in Human Narcolepsy
    John Black; Fiscal Year: 2004
    ..Long term objectives: This translational, multidisciplinary research will demonstrate fundamental insights into the cause of narcolepsy and will open avenues for new interventions and preventative measures for this debilitating disease. ..