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Genomes and GenesSpecies | Eduardo E BenarrochSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Involvement of medullary serotonergic groups in multiple system atrophyEduardo E Benarroch
Department of Neurology, Mayo Clinic, 811 Guggenheim Building, 200 First Street SW, Rochester, MN 55905, USA
Ann Neurol 55:418-22. 2004..Depletion of serotonergic neurons may contribute to impaired control of sympathetic outflow and other abnormalities in MSA...
Signaling molecules of the CNS as targets of autoimmunityEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN, USA Electronic address
Handb Clin Neurol 133:17-38. 2016....- Depletion of ventromedullary NK-1 receptor-immunoreactive neurons in multiple system atrophyEduardo E Benarroch
Department of Neurology, Mayo Foundation, Rochester, MN 55904, USA
Brain 126:2183-90. 2003.... 
Orthostatic intolerance without postural tachycardia: how much dysautonomia?Ajay K Parsaik
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Clin Auton Res 23:181-8. 2013..In this study, we focussed on the question of how much dysautonomia, besides orthostatic tachycardia, is there in POTS vs. OI, and how the two groups compare in regards to clinical, autonomic, laboratory, and exercise variables...- Loss of A5 noradrenergic neurons in multiple system atrophyEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Acta Neuropathol 115:629-34. 2008..The severity of cell loss was comparable to that of locus ceruleus neurons in these cases. Our results indicate that A5 neurons are severely affected in MSA and this may contribute to some of the manifestations of this synucleinopathy... - Brainstem respiratory control: substrates of respiratory failure of multiple system atrophyEduardo E Benarroch
Mayo Clinic, Department of Neurology, Rochester, Minnesota 55905, USA
Mov Disord 22:155-61. 2007..This finding may provide potential anatomical substrates for the respiratory manifestations of the disease... - Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosisShanu F Roemer
Department of Neurology, Mayo Clinic, College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Brain 130:1194-205. 2007..These findings strongly support a role for a complement activating AQP4-specific autoantibody as the initiator of the NMO lesion, and further distinguish NMO from MS... - Involvement of medullary regions controlling sympathetic output in Lewy body diseaseEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Brain 128:338-44. 2005..In LBD, orthostatic hypotension may be due primarily to involvement of sympathetic ganglion neurons rather than ventrolateral medulla neurons... - Depletion of putative chemosensitive respiratory neurons in the ventral medullary surface in multiple system atrophyEduardo E Benarroch
Department of Neurology, Rochester, MN, USA
Brain 130:469-75. 2007..This may provide a possible morphological basis for impaired respiratory chemosensitivity and central sleep apnoea in this disorder... - Involvement of hypocretin neurons in multiple system atrophyEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Acta Neuropathol 113:75-80. 2007..This is the first demonstration of loss of Hcrt/Orx neurons in MSA, which is consistent with a system degeneration of neurons involved in homeostatic function, including sleep and autonomic regulation, in this disorder... - Differential involvement of the periaqueductal gray in multiple system atrophyEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN, United States
Auton Neurosci 158:111-7. 2010..There was accumulation of glial cytoplasmic inclusions in all PAG columns in MSA. Our findings indicate involvement of the PAG columns in MSA, which may contribute to autonomic disturbances in this disorder... - Differential involvement of hypothalamic vasopressin neurons in multiple system atrophyEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Brain 129:2688-96. 2006..Loss of AVP neurons in the SCN may contribute to impaired circadian regulation of endocrine and autonomic functions... - Anhidrosis in multiple system atrophy involves pre- and postganglionic sudomotor dysfunctionElizabeth A Coon
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Mov Disord . 2016.... - HCN channels: function and clinical implicationsEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN, USA
Neurology 80:304-10. 2013..Experimental evidence indicates that HCN channels may also contribute to mechanisms of epilepsy and pain. The physiologic functions of HCN channels and their implications for neurologic disorders have been recently reviewed.(1-10)... - Deconditioning in patients with orthostatic intoleranceAjay Parsaik
Department of Neurology, Mayo Clinic, Rochester, MN, USA
Neurology 79:1435-9. 2012..To study the frequency and degree of deconditioning, clinical features, and relationship between deconditioning and autonomic parameters in patients with orthostatic intolerance... - Early seizure termination in ictal asystoleBrian D Moseley
Department of Neurology, Mayo Clinic, Rochester, MN, USA
Epilepsy Res 97:220-4. 2011..4±13 s in IA, 67±28.9 s in ictal bradycardia, and 82.1±31.1 in non-bradycardic seizures. These were significantly different (ANOVA, p<0.02). This suggests cerebral hypoxia-ischemia favors seizure termination... - Autopsy confirmed multiple system atrophy cases: Mayo experience and role of autonomic function testsValeria Iodice
Neurovascular and Autonomic Medicine Unit, Imperial College London, UK
J Neurol Neurosurg Psychiatry 83:453-9. 2012..Published autopsy confirmed cases have provided reasonable neurological characterisation but have lacked adequate autonomic function testing... - Glutamic acid decarboxylase autoimmunity with brainstem, extrapyramidal, and spinal cord dysfunctionSean J Pittock
Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Mayo Clin Proc 81:1207-14. 2006..To describe novel neurological manifestations associated with glutamic acid decarboxylase (GAD65) autoimmunity... - Ventilatory and cardiovascular responses to hypercapnia and hypoxia in multiple-system atrophyAxel Lipp
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Arch Neurol 67:211-6. 2010..The cardiovascular responses to chemoreflex activation in MSA have not been explored to date... - Preservation of branchimotor neurons of the nucleus ambiguus in multiple system atrophyEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurology 60:115-7. 2003..The number of neurons in the dorsal NA was not significantly different among the three groups. Neurons in the ventrolateral portion of the NA were depleted in MSA. Laryngeal stridor cannot be explained solely by neuronal loss in the NA... - Brainstem respiratory chemosensitivity: new insights and clinical implicationsEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurology 68:2140-3. 2007 - Medullary neuronal loss is not associated with α-synuclein burden in multiple system atrophyElizabeth A Coon
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Mov Disord 31:1802-1809. 2016.... - Metabotropic glutamate receptors: synaptic modulators and therapeutic targets for neurologic diseaseEduardo E Benarroch
Mayo Clinic, Department of Neurology, 200 First Street SW, West 8A Mayo Bldg, Rochester, MN 55905, USA
Neurology 70:964-8. 2008 - Depletion of mesopontine cholinergic and sparing of raphe neurons in multiple system atrophyEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurology 59:944-6. 2002..001) and laterodorsal tegmental nucleus (18 +/- 3 vs 47 +/- 4 cells/section, p < 0.001) in MSA. Whereas there was also depletion of locus ceruleus neurons, there was a striking preservation of rostral raphe neurons in MSA... - EEG changes in a patient with steroid-responsive encephalopathy associated with antibodies to thyroperoxidase (SREAT, Hashimoto's encephalopathy)Alcibiades J Rodriguez
Mayo Clinic Department of Neurology, Rochester, Minnesota, USA
J Clin Neurophysiol 23:371-3. 2006..These patients often show an excellent clinical improvement to immunosuppressive therapy, including corticosteroids. This case report documents the dramatic clinical and EEG improvement with steroid therapy... - Dynamic phases of peroneal and tibial intraneural ganglia formation: a new dimension added to the unifying articular theoryRobert J Spinner
Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
J Neurosurg 107:296-307. 2007..Atypical features, which occasionally are observed, have offered an opportunity to verify further and expand on the authors' proposed theory... - The ictal bradycardia syndrome: localization and lateralizationJeffrey W Britton
Divisions of Epilepsy and Clinical Neurophysiology EEG, Department of Neurology, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
Epilepsia 47:737-44. 2006..However, the evidence for this is inconsistent. We sought to assess critically the predictable value of ictal bradycardia for seizure localization and lateralization... - Paraventricular nucleus, stress response, and cardiovascular diseaseEduardo E Benarroch
Mayo Clinic, Dept of Neurology, 811 Guggenheim Building, 200 First Street SW, Rochester, MN 55905, USA
Clin Auton Res 15:254-63. 2005..The neurochemical control of the different subgroups of PVN neurons is complex. The PVN has been implicated in the pathophysiology of congestive heart failure and the metabolic syndrome... - Differential distribution of voltage-gated ion channels in cortical neurons: implications for epilepsyNicholas D Child
From the Department of Neurology, Mayo Clinic, Rochester, MN
Neurology 82:989-99. 2014.... - Orexin/hypocretin system and autonomic control: new insights and clinical correlationsDaniela Grimaldi
From the IRCCS Bologna Institute of Neurological Sciences D G, P C PRISM Laboratory A S and the Autonomic Unit P C, Department of Biomedical and Neuromotor Sciences, University of Bologna, Italy Department of Medicine D G, Sleep, Metabolism and Health Center, University of Chicago, IL and the Department of Neurology E E B, Mayo Clinic, Rochester, MN
Neurology 82:271-8. 2014..3-6) The present review focuses on the role of the orexin system in autonomic control and its potential implications in human NC. .. - Microglia: Multiple roles in surveillance, circuit shaping, and response to injuryEduardo E Benarroch
From the Department of Neurology, Mayo Clinic, Rochester, MN
Neurology 81:1079-88. 2013..Microglial dysfunction may also contribute to genetic neurobehavioral disorders, such as Rett syndrome. There are several comprehensive reviews on all these topics... - Clinical features and autonomic testing predict survival in multiple system atrophyElizabeth A Coon
1 Department of Neurology, Mayo Clinic, Rochester, MN, USA
Brain 138:3623-31. 2015..Autonomic testing adds an additional, independent predictor of survival, demonstrating its value not only in the diagnosis of multiple system atrophy but also as prognostic marker... - Histaminergic tuberomammillary neuron loss in multiple system atrophy and dementia with Lewy bodiesEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Mov Disord 30:1133-9. 2015..All of these functions are affected in multiple system atrophy and dementia with Lewy bodies... - Neocortical interneurons: functional diversity and clinical correlationsEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN, USA
Neurology 81:273-80. 2013..There are many comprehensive reviews on GABAergic interneuron heterogeneity, development, plasticity, function in shaping cortical activity, and involvement in disease.(1-13.) .. - Adenosine and its receptors: multiple modulatory functions and potential therapeutic targets for neurologic diseaseEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, West 8A Mayo Bldg, Rochester, MN 55905, USA
Neurology 70:231-6. 2008 - Suprachiasmatic nucleus and melatonin: reciprocal interactions and clinical correlationsEduardo E Benarroch
Mayo Clinic, Department of Neurology, 200 First Street SW, West 8A Mayo Bldg, Rochester, MN 55905, USA
Neurology 71:594-8. 2008 - Descending monoaminergic pain modulation: bidirectional control and clinical relevanceEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, West 8A Mayo Bldg, Rochester, MN 55905, USA
Neurology 71:217-21. 2008 - N-acetylaspartate and N-acetylaspartylglutamate: neurobiology and clinical significanceEduardo E Benarroch
Mayo Clinic, Department of Neurology, 200 First Street SW, West 8A Mayo Bldg, Rochester, MN 55905, USA
Neurology 70:1353-7. 2008 - Aquaporin-4, homeostasis, and neurologic diseaseEduardo E Benarroch
Mayo Clinic, 200 First Street SW, West 8A Mayo Bldg or 811 Guggenheim Bldg, Rochester, MN 55905, USA
Neurology 69:2266-8. 2007 - Tissue plasminogen activator: beyond thrombolysisEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurology 69:799-802. 2007 - Neurosteroids: endogenous modulators of neuronal excitability and plasticityEduardo E Benarroch
Mayo Clinic, Rochester, MN 55905, USA
Neurology 68:945-7. 2007 - Brain glucose transporters: implications for neurologic diseaseEduardo E Benarroch
From the Department of Neurology, Mayo Clinic, Rochester, MN
Neurology 82:1374-9. 2014..1-7.) .. - Pedunculopontine nucleus: functional organization and clinical implicationsEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN, USA
Neurology 80:1148-55. 2013..There have been several recent reviews on the PPN focused on its neurochemical organization and connectivity, physiology, involvement in parkinsonian syndromes, and as a target for DBS.(1-12.).. - Insulin-like growth factors in the brain and their potential clinical implicationsEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Neurology 79:2148-53. 2012..The insulin-like peptides, their receptors, effects in the nervous system, and potential clinical correlations have been the subject of several recent reviews.(1-6)... - Rho GTPases: role in dendrite and axonal growth, mental retardation, and axonal regenerationEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurology 68:1315-8. 2007 - Amphiphysin autoimmunity: paraneoplastic accompanimentsSean J Pittock
Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Ann Neurol 58:96-107. 2005..01). Overall, a minority of women (39%) and men (12%) had stiff-man phenomena. Only 10% of women (some with lung carcinoma) and 4% of men fulfilled diagnostic criteria for stiff-man syndrome... - A PRESsing dissectionTamika M Burrus
Mayo Clinic, Rochester, MN, USA
Neurocrit Care 13:411-3. 2010..When this occurs labile hypertension may be observed with its own complications, including but not limited to the clinico-radiographic entity, posterior reversible encephalopathy syndrome (PRES)... - Brainstem in multiple system atrophy: clinicopathological correlationsEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Cell Mol Neurobiol 23:519-26. 2003..6. Loss of cholinergic mesopontine neurons, in the setting of loss of locus ceruleus neurons and preservation of rostral raphe neurons, may contribute to REM sleep abnormalities in MSA... - Brain cholesterol metabolism and neurologic diseaseEduardo E Benarroch
Mayo Clinic, Department of Neurology, Rochester, MN 55905, USA
Neurology 71:1368-73. 2008 - The midline and intralaminar thalamic nuclei: anatomic and functional specificity and implications in neurologic diseaseEduardo E Benarroch
Mayo Clinic, Department of Neurology, 200 First Street SW, West 8A Mayo Bldg, Rochester, MN 55905, USA
Neurology 71:944-9. 2008 - Effect of position on valsalva maneuver: supine versus 20 degree positionElizabeth R Vogel
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
J Clin Neurophysiol 25:313-6. 2008..We recommend this modification for laboratory evaluation of the VM, whenever a flat-top response is seen... - Subthalamic nucleus and its connections: Anatomic substrate for the network effects of deep brain stimulationEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurology 70:1991-5. 2008 - Thermoregulation: recent concepts and remaining questionsEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurology 69:1293-7. 2007 - Lipid rafts, protein scaffolds, and neurologic diseaseEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, West 8A Mayo Bldg or 811 Guggenheim Bldg, Rochester, MN 55905, USA
Neurology 69:1635-9. 2007 - Enteric nervous system: functional organization and neurologic implicationsEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Neurology 69:1953-7. 2007 - Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's diseaseJennifer L Whitwell
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Brain 130:708-19. 2007..Damage to this network of structures in DLB may affect a number of different neurotransmitter systems which in turn may contribute to a number of the core clinical features of DLB... - GABAA receptor heterogeneity, function, and implications for epilepsyEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurology 68:612-4. 2007 - Treatment of paroxysmal sympathetic hyperactivityAlejandro A Rabinstein
Mayo Clinic, Department of Neurology, W8B, 200 First Street SW, Rochester, MN 55905, USA
Curr Treat Options Neurol 10:151-7. 2008.... - Postural tachycardia syndrome: a heterogeneous and multifactorial disorderEduardo E Benarroch
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 87:1214-25. 2012..Studies were limited to those published in English. Other articles were identified from bibliographies of the retrieved articles... - New findings on the neuropathology of multiple system atrophyEduardo E Benarroch
Neurophysiological Laboratory, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Auton Neurosci 96:59-62. 2002.... - Clinical cues for detecting ictal asystoleGena R Ghearing
Dept of Neurology, Mayo Clinic Rochester, Rochester, MN 55905, USA
Clin Auton Res 17:221-6. 2007..Recognition of ictal asystole is important as treatment with both antiepileptic drugs and cardiac pacing may be necessary. The purpose of this study was to identify clinical cues to aid in the detection of ictal asystole... - TRP channels: functions and involvement in neurologic diseaseEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Neurology 70:648-52. 2008 - Neuron-astrocyte interactions: partnership for normal function and disease in the central nervous systemEduardo E Benarroch
Department of Neurology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 80:1326-38. 2005..Disturbances of these neuron-astrocyte interactions are likely to play an important role in neurologic disorders including cerebral ischemia, neurodegeneration, migraine, cerebral edema, and hepatic encephalopathy... - Sodium channels and painEduardo E Benarroch
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Neurology 68:233-6. 2007 - Neural control of the gastrointestinal tract: implications for Parkinson diseaseMaria G Cersosimo
Parkinson s Disease and Movement Disorder Unit, Hospital de Clinicas, University of Buenos Aires, Argentina
Mov Disord 23:1065-75. 2008..This early involvement provides insights into the pathophysiology of gastrointestinal dysmotility in this disorder and may constitute an important step in the etiopathogenesis of Lewy body disease... - Quantitative study of salivary secretion in Parkinson's diseaseOmar R Tumilasci
Departamento de Fisiologia, Laboratorio de Neurofisiologia, Facultad de Medicina, and Programa de Parkinson y Movimientos Anormales, Instituto de Neurociencias del Hospital de Clínicas, Universidad de Buenos Aires, Buenos Aires, Argentina
Mov Disord 21:660-7. 2006..Domperidone may have a peripheral effect that potentiates reflex salivary secretion. Salivary composition is abnormal in PD and is not affected by levodopa treatment... - Neurodegeneration involving putative respiratory neurons in Perry syndromeYoshio Tsuboi
Department of Neurology, Fukuoka University, Fukuoka, Japan
Acta Neuropathol 115:263-8. 2008.... - Neurovascular unit dysfunction: a vascular component of Alzheimer disease?Eduardo E Benarroch
Neurology 68:1730-2. 2007 - Dopamine beta-hydroxylase deficiency involves the central autonomic networkWilliam P Cheshire
Acta Neuropathol 112:227-9. 2006 - Autonomic and cognitive dysfunction in Parkinson's diseaseJuan Idiaquez
Universidad de Valparaiso, Valparaiso, Chile
Clin Auton Res 17:93-8. 2007....