Bernd Fritzsch

Summary

Affiliation: Creighton University
Country: USA

Publications

  1. request reprint
    Fritzsch B. How does the urodele ear develop?. Int J Dev Biol. 1996;40:763-71 pubmed
    ....
  2. request reprint
    Fritzsch B, Signore M, Simeone A. Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears. Dev Genes Evol. 2001;211:388-96 pubmed
    ..It also affects constriction of the two main foramina in the ear, but not their initial formation. Otx1 is thus causally related to horizontal canal morphogenesis as well as morphogenesis of these foramina. ..
  3. Fritzsch B, Matei V, Nichols D, Bermingham N, Jones K, Beisel K, et al. Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention. Dev Dyn. 2005;233:570-83 pubmed
    ..Few fibers remain to the saccule, utricle, and the base of the cochlea, all areas with few or no Bdnf-beta-galactosidase-positive cells. Thus, retention of fibers is possible with BDNF, even in the absence of differentiated hair cells. ..
  4. Fritzsch B, Pauley S, Matei V, Katz D, Xiang M, Tessarollo L. Mutant mice reveal the molecular and cellular basis for specific sensory connections to inner ear epithelia and primary nuclei of the brain. Hear Res. 2005;206:52-63 pubmed
    ..This conclusion is derived from data that show no recognizable central projection deviation, even if fibers are massively rerouted in the periphery, as in Ntf3(tgBDNF) mice in which vestibular fibers project to the cochlea. ..
  5. Fritzsch B, Beisel K, Pauley S, Soukup G. Molecular evolution of the vertebrate mechanosensory cell and ear. Int J Dev Biol. 2007;51:663-78 pubmed
    ..Recent advances in our molecular understanding of ear and brain development provide novel avenues to this neglected aspect of auditory neurosensory evolution...

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Detail Information

Publications5

  1. request reprint
    Fritzsch B. How does the urodele ear develop?. Int J Dev Biol. 1996;40:763-71 pubmed
    ....
  2. request reprint
    Fritzsch B, Signore M, Simeone A. Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears. Dev Genes Evol. 2001;211:388-96 pubmed
    ..It also affects constriction of the two main foramina in the ear, but not their initial formation. Otx1 is thus causally related to horizontal canal morphogenesis as well as morphogenesis of these foramina. ..
  3. Fritzsch B, Matei V, Nichols D, Bermingham N, Jones K, Beisel K, et al. Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention. Dev Dyn. 2005;233:570-83 pubmed
    ..Few fibers remain to the saccule, utricle, and the base of the cochlea, all areas with few or no Bdnf-beta-galactosidase-positive cells. Thus, retention of fibers is possible with BDNF, even in the absence of differentiated hair cells. ..
  4. Fritzsch B, Pauley S, Matei V, Katz D, Xiang M, Tessarollo L. Mutant mice reveal the molecular and cellular basis for specific sensory connections to inner ear epithelia and primary nuclei of the brain. Hear Res. 2005;206:52-63 pubmed
    ..This conclusion is derived from data that show no recognizable central projection deviation, even if fibers are massively rerouted in the periphery, as in Ntf3(tgBDNF) mice in which vestibular fibers project to the cochlea. ..
  5. Fritzsch B, Beisel K, Pauley S, Soukup G. Molecular evolution of the vertebrate mechanosensory cell and ear. Int J Dev Biol. 2007;51:663-78 pubmed
    ..Recent advances in our molecular understanding of ear and brain development provide novel avenues to this neglected aspect of auditory neurosensory evolution...