- Shaw G, Nelson V, Iovannisci D, Finnell R, Lammer E. Maternal occupational chemical exposures and biotransformation genotypes as risk factors for selected congenital anomalies. Am J Epidemiol. 2003;157:475-84 pubmed..Although potential associations were observed, most results suggested that maternal occupational chemical exposures did not contribute substantially to the occurrence of these anomalies in this California population. ..
- Shaw G, Iovannisci D, Yang W, Finnell R, Carmichael S, Cheng S, et al. Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. Am J Med Genet A. 2005;138:21-6 pubmed..In particular, NPPA appears to be a good candidate gene for conotruncal defects and warrants further investigation. ..
- Shaw G, Iovannisci D, Yang W, Finnell R, Carmichael S, Cheng S, et al. Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial clefts. Am J Epidemiol. 2005;162:1207-14 pubmed..6, 95% CI: 2.1, 10.2; for 894T, OR = 4.4, 95% CI: 1.8, 10.7). No similar patterns were observed for risk of cleft palate. ..
- Shaw G, Zhu H, Lammer E, Yang W, Finnell R. Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial and conotruncal heart defects. Am J Epidemiol. 2003;158:747-52 pubmed..Thus, this study found modest evidence for a gene-nutrient interaction between infant RFC1 genotype and periconceptional intake of vitamins on the risk of conotruncal defects. ..