Chad M Fuller
Affiliation: Veterinary Laboratories Agency
- Development of an L gene real-time reverse-transcription PCR assay for the detection of avian paramyxovirus type 1 RNA in clinical samplesChad M Fuller
Veterinary Laboratories Agency, Surrey, UK
Arch Virol 155:817-23. 2010..05%) and specificity (98.18%) when compared with virus isolation in embryonated fowls' eggs. It is proposed that this assay could provide a first-line screening tool for the detection of APMV-1 in clinical samples...
- Development of a real-time reverse-transcription PCR for the detection and simultaneous pathotyping of Newcastle disease virus isolates using a novel probeChad Marshal Fuller
Virology Department, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, KT15 3NB, UK
Arch Virol 154:929-37. 2009..This assay demonstrates a rapid means for simultaneous detection and pathotyping of notifiable avian disease due to NDV...
- Partial characterisation of five cloned viruses differing in pathogenicity, obtained from a single isolate of pigeon paramyxovirus type 1 (PPMV-1) following passage in fowls' eggsC M Fuller
Virology Department, Veterinary Laboratories Agency, Addlestone, Surrey, UK
Arch Virol 152:1575-82. 2007..49, T --> C at position 1769 in the untranslated region of the fusion gene and G --> A at position 437 of the HN gene, resulting in the amino acid change G --> R at position 116 in the HN protein...
- The long view: a selective review of 40 years of Newcastle disease researchDennis J Alexander
Virology Department, Animal Health and Veterinary Laboratories Agency, Weybridge, Addlestone, Surrey, KT15 3NB, UK
Avian Pathol 41:329-35. 2012..The authors suggest areas in which future research could or should be undertaken...
- Inactivation of the infectivity of two highly pathogenic avian influenza viruses and a virulent Newcastle disease virus by ultraviolet radiationDavid Sutton
a Virology Department, Animal Health and Veterinary Laboratories Agency, New Haw, Surrey, UK
Avian Pathol 42:566-8. 2013..The time taken for a reduction in titre of 1 log10 median tissue culture infectious dose for each virus was: NDV, 69 min; H7N1 HPAI virus, 158 min; and H5N1 HPAI, virus 167 min. ..
- A molecular epidemiological investigation of isolates of the variant avian paramyxovirus type 1 virus (PPMV-1) responsible for the 1978 to present panzootic in pigeonsE W Aldous
Virology Department, Veterinary Laboratories Agency Weybridge, Surrey, UK
Avian Pathol 33:258-69. 2004..There were two large distinguishable groups, 4bi and 4bii. The earliest isolate available, PIQPI78442, isolated in 1978 in Iraq, was situated at the node from which the two groups diverge...
- Outbreak of Newcastle disease due to pigeon paramyxovirus type 1 in grey partridges (Perdix perdix) in Scotland in October 2006R M Irvine
Virology Department, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey KT15 3NB
Vet Rec 165:531-5. 2009..However, the virus could not be isolated from or detected in dead pigeons collected from the affected buildings...
- Infection dynamics of highly pathogenic avian influenza and virulent avian paramyxovirus type 1 viruses in chickens, turkeys and ducksE W Aldous
Virology Department, Surrey, UK
Avian Pathol 39:265-73. 2010..6) EID(50)), but none died. In marked contrast, chickens were shown to be extremely susceptible to infection and all infected chickens died (ID(50)/LD(50)=10(1.9) EID(50))...
- Phylogenetic analysis of the nucleotide sequences for the HN gene of 22 avian paramyxovirus type 2 viruses reveals marked heterogeneitySahar Mahmood
Virology Department, Veterinary Laboratories Agency Weybridge, New Haw, Addlestone, UK
Avian Pathol 39:453-8. 2010....
- pH alterations "reset" Ca2+ sensitivity of brain Na+ channel 2, a degenerin/epithelial Na+ ion channel, in planar lipid bilayersB K Berdiev
Department of Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, Alabama 35294-0005, USA
J Biol Chem 276:38755-61. 2001..These results show that BNaC-2 is an amiloride-sensitive sodium channel and suggest that pH activation of these channels could be, in part, a consequence of H(+) "interference" with channel regulation by Ca(2+)...
- Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary glandA D Gruber
Cancer Biology Laboratories, Department of Molecular Medicine, Cornell University College of Veterinary Medicine, Ithaca, New York 14853, USA
Am J Physiol 276:C1261-70. 1999..Expression in human trachea and lung suggests that hCLCA2 may play a role in the complex pathogenesis of cystic fibrosis...
- Genomic cloning, molecular characterization, and functional analysis of human CLCA1, the first human member of the family of Ca2+-activated Cl- channel proteinsA D Gruber
Cancer Biology Laboratories, Department of Molecular Medicine, Cornell University College of Veterinary Medicine, Ithaca, New York, 14853, USA
Genomics 54:200-14. 1998..4 pS. These findings suggest that human CLCA1 mediates a Ca2+-activated Cl- conductance in the human intestine and make it an interesting candidate as a modulating factor in the pathogenesis of cystic fibrosis...
- Cloning of an epithelial chloride channel from bovine tracheaS A Cunningham
Department of Physiology, University of Alabama at Birmingham 35294, USA
J Biol Chem 270:31016-26. 1995....
- Cloning of a bovine renal epithelial Na+ channel subunitC M Fuller
Department of Physiology and Biophysics, University of Alabama at Birmingham 35294, USA
Am J Physiol 269:C641-54. 1995..alpha-bENaC therefore represents a novel isoform of a growing family of epithelial Na+ channels...