Genomes and Genes
J P Venables
Affiliation: University of Newcastle
- Venables J, Ruggiu M, Cooke H. The RNA-binding specificity of the mouse Dazl protein. Nucleic Acids Res. 2001;29:2479-83 pubmed..CDC25C 5' UTR also interacted specifically with Dazl in vitro. The tri-hybrid screen retrieved UTRs of known genes that may be physiological substrates of Dazl. ..
- Venables J, Burn J. EASI--enrichment of alternatively spliced isoforms. Nucleic Acids Res. 2006;34:e103 pubmed..These contain missing exons, cryptic splice sites or include completely novel exons. EASI beads are stable for months in the fridge and can be easily combined with standard protocols to speed the cloning of novel transcripts. ..
- Venables J, Bourgeois C, Dalgliesh C, Kister L, Stevenin J, Elliott D. Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon. Hum Mol Genet. 2005;14:2289-303 pubmed..Therefore, our data imply an evolutionarily conserved role for Tra2 proteins in spermatogenesis and suggest that an elevated concentration of Tra2beta may convert it into a tissue-specific splicing factor. ..