Sturrock M, Terry A, Xirodimas D, Thompson A, Chaplain M. Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling. Bull Math Biol. 2012;74:1531-79 pubmed publisher
..For the extended p53-Mdm2 model, we consider the effect of microtubule-disrupting drugs and proteasome inhibitor drugs, obtaining results that are in agreement with experimental studies. ..