Helen P Price
Affiliation: University of York
- Price H, Guther M, Ferguson M, Smith D. Myristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects. Mol Biochem Parasitol. 2010;169:55-8 pubmed publisher..Critically we show that following NMT knockdown, T. brucei bloodstream form cells are unable to establish an infection in a mouse model, therefore providing further validation of this enzyme as a target for drug development...