- Differential global gene expression in cystic fibrosis nasal and bronchial epitheliumVarrie Ogilvie
Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, UK
Genomics 98:327-36. 2011..We conclude that CF and non-CF nasal and bronchial epithelium are transcriptionally distinct and CF nasal epithelium is not a good surrogate for the lung respiratory epithelium...
- Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivoUta Griesenbach
Department of Gene Therapy, Faculty of Medicine, National Heart and Lung Institute, Imperial College, London, UK
Respir Res 7:26. 2006..The cationic lipid Genzyme lipid (GL) 67 is the current "gold-standard" for in vivo lung gene transfer. Here, we assessed, if GL67 mediated uptake of siRNAs and asODNs into airway epithelium in vivo...