S J Lewis
Affiliation: University of Bristol
Lewis S, Smith G. Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach. Cancer Epidemiol Biomarkers Prev. 2005;14:1967-71 pubmed
..The two different processes operating as a result of the ALDH2 genotype have implications for the interpretation of studies using the Mendelian randomization paradigm. ..
Lewis S, Araya R, Smith G, Freathy R, Gunnell D, Palmer T, et al
. Smoking is associated with, but does not cause, depressed mood in pregnancy--a mendelian randomization study. PLoS ONE. 2011;6:e21689 pubmed publisher
Lewis S, Araya R, Leary S, Smith G, Ness A. Folic acid supplementation during pregnancy may protect against depression 21 months after pregnancy, an effect modified by MTHFR C677T genotype. Eur J Clin Nutr. 2012;66:97-103 pubmed publisher
..Low folate is unlikely to be an important risk factor for depression during pregnancy and for postpartum depression, but may be a risk factor for depression outside of pregnancy, especially among women with the MTHFR C677T TT genotype. ..
Lewis S, Zuccolo L, Davey Smith G, Macleod J, Rodriguez S, Draper E, et al
. Fetal alcohol exposure and IQ at age 8: evidence from a population-based birth-cohort study. PLoS ONE. 2012;7:e49407 pubmed publisher
..05 to 1.36) p=0.80), p-value for interaction â€Š=0.009). A further genetic variant associated with alcohol metabolism in mothers was associated with their child's IQ, but again only among mothers who drank during pregnancy. ..
Harrison S, Lennon R, Holly J, Higgins J, Gardner M, Perks C, et al
. Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis. Cancer Causes Control. 2017;28:497-528 pubmed publisher
..IGF-I is a potential mechanism underlying the observed associations between milk intake and prostate cancer risk. ..
Harrison S, Lewis S, Hall A, Vuckovic D, Girotto G, Martin R, et al
. Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium. BMC Med Genomics. 2015;8:48 pubmed publisher
..No individual SNPs reached sample-wide significance in both ALSPAC and G-EAR. This is the first report of a possible association between LCP1 and hearing function. ..
Lewis S, Leary S, Davey Smith G, Ness A. Body composition at age 9 years, maternal folate intake during pregnancy and methyltetrahydrofolate reductase (MTHFR) C677T genotype. Br J Nutr. 2009;102:493-6 pubmed publisher
..We also looked at maternal and offspring's MTHFR C677T genotype in relation to offspring body composition. We found no evidence to support the hypothesis that intra-uterine exposure to folate influences childhood body composition. ..
Lewis S, Gardner M, Higgins J, Holly J, Gaunt T, Perks C, et al
. Developing the WCRF International/University of Bristol Methodology for Identifying and Carrying Out Systematic Reviews of Mechanisms of Exposure-Cancer Associations. Cancer Epidemiol Biomarkers Prev. 2017;26:1667-1675 pubmed publisher
..i>Cancer Epidemiol Biomarkers Prev; 26(11); 1667-75. ©2017 AACR. ..