Eric W F W Alton


Affiliation: Imperial College
Country: UK


  1. Paul Smith M, Pytel K, GĂ©linas J, McIntosh J, Pringle I, Davies L, et al. The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins. Gene Ther. 2018;: pubmed publisher
    ..These data broaden the use of this vector platform for a large range of disease indications. ..
  2. Alton E, Armstrong D, Ashby D, Bayfield K, Bilton D, Bloomfield E, et al. Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial. Lancet Respir Med. 2015;3:684-691 pubmed publisher
    ..Medical Research Council/National Institute for Health Research Efficacy and Mechanism Evaluation Programme. ..
  3. request reprint
    Leoni G, Wasowicz M, Chan M, Meng C, Farley R, Brody S, et al. Ex Vivo and In Vivo Lentivirus-Mediated Transduction of Airway Epithelial Progenitor Cells. Curr Gene Ther. 2015;15:581-90 pubmed
    ..These results indicate that our lentiviral vector can transduce progenitor basal cells in vivo, although transduction required denudation of the surface epithelium prior to vector administration. ..