P E Martin

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. ncbi request reprint Properties of connexin26 gap junctional proteins derived from mutations associated with non-syndromal heriditary deafness
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN, UK
    Hum Mol Genet 8:2369-76. 1999
  2. ncbi request reprint Analysis of gap junction assembly using mutated connexins detected in Charcot-Marie-Tooth X-linked disease
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, UK
    J Neurochem 74:711-20. 2000
  3. pmc Targeting motifs and functional parameters governing the assembly of connexins into gap junctions
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    Biochem J 349:281-7. 2000
  4. ncbi request reprint Gap junction assembly: multiple connexin fluorophores identify complex trafficking pathways
    P E Martin
    Wales Heart Research Institute and Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, UK
    Cell Commun Adhes 8:243-8. 2001
  5. ncbi request reprint Rapid determination of gap junction formation using HeLa cells microinjected with cDNAs encoding wild-type and chimeric connexins
    C H George
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom
    Biochem Biophys Res Commun 247:785-9. 1998
  6. ncbi request reprint Assembly of gap junction channels: mechanism, effects of calmodulin antagonists and identification of connexin oligomerization determinants
    S Ahmad
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff, Wales, UK
    Eur J Biochem 268:4544-52. 2001
  7. ncbi request reprint Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    J Cell Sci 114:3845-55. 2001

Detail Information

Publications7

  1. ncbi request reprint Properties of connexin26 gap junctional proteins derived from mutations associated with non-syndromal heriditary deafness
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN, UK
    Hum Mol Genet 8:2369-76. 1999
    ..The results point to the conclusion that mutations in the transmembrane domains of connexin proteins influence gap junction assembly...
  2. ncbi request reprint Analysis of gap junction assembly using mutated connexins detected in Charcot-Marie-Tooth X-linked disease
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, UK
    J Neurochem 74:711-20. 2000
    ..The results show that modifications in trafficking and assembly of gap junction channels emerge as a major feature of Charcot-Marie-Tooth X-linked disease...
  3. pmc Targeting motifs and functional parameters governing the assembly of connexins into gap junctions
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    Biochem J 349:281-7. 2000
    ..The studies show that expression of these Cx--GFP constructs in mammalian cells allowed an analysis of amino acid residues involved in gap-junction assembly...
  4. ncbi request reprint Gap junction assembly: multiple connexin fluorophores identify complex trafficking pathways
    P E Martin
    Wales Heart Research Institute and Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, UK
    Cell Commun Adhes 8:243-8. 2001
    ..The results indicate that multiple intracellular connexin trafficking routes exist and provide a further mechanism for regulating the connexin composition of gap junctions and thus specificity in intercellular signalling...
  5. ncbi request reprint Rapid determination of gap junction formation using HeLa cells microinjected with cDNAs encoding wild-type and chimeric connexins
    C H George
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom
    Biochem Biophys Res Commun 247:785-9. 1998
    ....
  6. ncbi request reprint Assembly of gap junction channels: mechanism, effects of calmodulin antagonists and identification of connexin oligomerization determinants
    S Ahmad
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff, Wales, UK
    Eur J Biochem 268:4544-52. 2001
    ..The results indicate that amino-acid sequences in the third transmembrane domain and a calmodulin-binding domain in the cytoplasmic tail of Cx32 are likely candidates for regulating connexin oligomerization...
  7. ncbi request reprint Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    J Cell Sci 114:3845-55. 2001
    ....