Phuc V Pham
Truong N, Bui K, Van Pham P. Characterization of Senescence of Human Adipose-Derived Stem Cells After Long-Term Expansion. Adv Exp Med Biol. 2018;: pubmed publisher
..In conclusion, hASCs exhibited some particular characteristics of aged stem cells when the number of subculture cells increased. However, up to passage 10, ASCs also retained almost all of the characteristics of MSCs. ..
Phuc P, Ngoc V, Lam D, Tam N, Viet P, Ngoc P. Isolation of three important types of stem cells from the same samples of banked umbilical cord blood. Cell Tissue Bank. 2012;13:341-51 pubmed publisher
Van Pham P, Thi My Nguyen P, Thai Quynh Nguyen A, Minh Pham V, Nguyen Tu Bui A, Thi Tung Dang L, et al
. Improved differentiation of umbilical cord blood-derived mesenchymal stem cells into insulin-producing cells by PDX-1 mRNA transfection. Differentiation. 2014;87:200-8 pubmed publisher
..These results indicate that PDX-1 mRNA may offer a promising approach to produce safe IPCs for clinical diabetes mellitus treatment. ..
Van Pham P, Phan N. Production of good manufacturing practice-grade human umbilical cord blood-derived mesenchymal stem cells for therapeutic use. Methods Mol Biol. 2015;1283:73-85 pubmed publisher
..The obtained UCB-MSCs are free of allogenous or xenogenous proteins. In addition, these MSCs could maintain the MSC phenotype in long-term culture. ..
Pham T, Nguyen T, Van Bui A, Nguyen M, Van Pham P. Fetal heart extract facilitates the differentiation of human umbilical cord blood-derived mesenchymal stem cells into heart muscle precursor cells. Cytotechnology. 2016;68:645-58 pubmed publisher
..These properties are similar to properties of heart muscle precursor cells in vivo. These results demonstrated that the fetal HE facilitates the differentiation process of human UCB-MSCs into heart muscle precursor cells. ..
Nhung T, Nam N, Nguyen N, Nghia H, Van Thanh N, Ngoc P, et al
. A comparison of the chemical and liver extract-induced hepatic differentiation of adipose derived stem cells. In Vitro Cell Dev Biol Anim. 2015;51:1085-92 pubmed publisher
..This study reveals the potential of mesenchymal stem cell differentiation in the liver extract, which supports further preclinical and clinical research on the application of ADSCs in ESLD treatment. ..
Van Pham P, Tran N, Phan N, Vu N, Phan N. Vitamin C stimulates human gingival stem cell proliferation and expression of pluripotent markers. In Vitro Cell Dev Biol Anim. 2016;52:218-27 pubmed publisher
..More importantly, GSCs also maintained their stemness with MSC phenotypes and failed to cause tumors in nude athymic mice. Our results show that AA is a suitable factor to stimulate GSC proliferation. ..
Van Pham P, Truong N, Le P, Tran T, Vu N, Bui K, et al
. Isolation and proliferation of umbilical cord tissue derived mesenchymal stem cells for clinical applications. Cell Tissue Bank. 2016;17:289-302 pubmed publisher
..Replacing FBS with aPRP in the culture medium for UC tissues allowed the successful isolation of UC-MSCs that satisfy the minimum standards for clinical applications. ..
Van Pham P. Clinical trials for stem cell transplantation: when are they needed?. Stem Cell Res Ther. 2016;7:65 pubmed publisher
..However, the point at which stem cell clinical trials are essential remains unclear. This commentary discusses when stem cell clinical trials are essential for stem cell transplantation therapies. ..