Claudia L Trevino
Chavez J, De Blas G, de la Vega Beltrán J, Nishigaki T, Chirinos M, González González M, et al
. The opening of maitotoxin-sensitive calcium channels induces the acrosome reaction in human spermatozoa: differences from the zona pellucida. Asian J Androl. 2011;13:159-65 pubmed publisher
..Notably, edelfosine also inhibited the MTx-induced mouse sperm AR but not that of the human, suggesting that toxin-induced AR is PLC-dependent in mice and PLC-independent in humans. ..
SÃ¡nchez Carranza O, Torres RodrÃguez P, Darszon A, TreviÃ±o C, LÃ³pez GonzÃ¡lez I. Pharmacology of hSlo3 channels and their contribution in the capacitation-associated hyperpolarization of human sperm. Biochem Biophys Res Commun. 2015;466:554-9 pubmed publisher
..While the pharmacological correlation analysis of the hSlo3 currents and the CAH confirmed the participation of hSlo3 channels, it suggests that additional K(+) channels may be involved, in particular Slo1 channels. ..
Mata MartÃnez E, Darszon A, TreviÃ±o C. pH-dependent Ca+2 oscillations prevent untimely acrosome reaction in human sperm. Biochem Biophys Res Commun. 2018;497:146-152 pubmed publisher
..Pharmacological inhibition of Ca2+ oscillations restores the ability of spermatozoa to undergo the AR when exposed to progesterone, even if capacitated at pHe 6.5. ..
SaldÃvar HernÃ¡ndez A, GonzÃ¡lez GonzÃ¡lez M, SÃ¡nchez TusiÃ© A, Maldonado Rosas I, LÃ³pez P, TreviÃ±o C, et al
. Human sperm degradation of zona pellucida proteins contributes to fertilization. Reprod Biol Endocrinol. 2015;13:99 pubmed publisher
..These findings suggest that localized degradation of ZP proteins by sperm is probably involved in ZP penetration and may be of help in understanding the mechanisms of fertilization in humans. ..
JosÃ© O, Torres RodrÃguez P, Forero Quintero L, ChÃ¡vez J, De la Vega BeltrÃ¡n J, Carta F, et al
. Carbonic anhydrases and their functional differences in human and mouse sperm physiology. Biochem Biophys Res Commun. 2015;468:713-8 pubmed publisher
..Finally, we found that CA inhibition increases the acrosome reaction in capacitated human sperm, but not in capacitated mouse sperm. ..