Research Topics

Mohd Zaini Asmawi


Affiliation: Universiti Sains Malaysia
Country: Malaysia


  1. Yusoff N, Ahmad M, Al Hindi B, Widyawati T, Yam M, Mahmud R, et al. Aqueous Extract of Nypa fruticans Wurmb. Vinegar Alleviates Postprandial Hyperglycemia in Normoglycemic Rats. Nutrients. 2015;7:7012-26 pubmed publisher
  2. Zarzour R, Alshawsh M, Asif M, Al Mansoub M, Mohamed Z, Ahmad M, et al. Adipocytokine Regulation and Antiangiogenic Activity Underlie the Molecular Mechanisms of Therapeutic Effects of Phyllanthus niruri against Non-Alcoholic Fatty Liver Disease. Nutrients. 2018;10: pubmed publisher
    ..niruri against NAFLD might be attributed to its antiangiogenic effect, as well as to the regulation of adipocytokines and reducing the expression of adipogenic genes. ..
  3. Loh Y, Tan C, Ch ng Y, Ahmad M, Asmawi M, Yam M. Overview of Antagonists Used for Determining the Mechanisms of Action Employed by Potential Vasodilators with Their Suggested Signaling Pathways. Molecules. 2016;21:495 pubmed publisher
    ..However, the most appropriate antagonists that should be utilized have never been suggested and elaborated before, hence the reason for this review. ..
  4. Chan S, Lee W, Asmawi M, Tan S. Chiral liquid chromatography-mass spectrometry (LC-MS/MS) method development for the detection of salbutamol in urine samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2016;1025:83-91 pubmed publisher
    ..1-10ng/mL with limit of quantification at 0.3ng/mL. Analysis of the QC samples showed intra- and inter-assay precisions to be less than 5.04%, and recovery ranging from 83.82 to 102.33%. ..
  5. Bello I, Usman N, Mahmud R, Asmawi M. Mechanisms underlying the antihypertensive effect of Alstonia scholaris. J Ethnopharmacol. 2015;175:422-31 pubmed publisher
    ..The results from this study suggests that A. scholaris exerts vasodilation via calcium channels blockade, direct activation of soluble guanylate cyclase and possibly by also inhibiting the formation of inositol 1, 4, 5-triphosphate. ..
  6. Al Zarzour R, Ahmad M, Asmawi M, Kaur G, Saeed M, Al Mansoub M, et al. Phyllanthus Niruri Standardized Extract Alleviates the Progression of Non-Alcoholic Fatty Liver Disease and Decreases Atherosclerotic Risk in Sprague-Dawley Rats. Nutrients. 2017;9: pubmed publisher
    ..Ellagic acid and phyllanthin were identified as major compounds. These results suggest that P. niruri could be further developed as a novel natural hepatoprotective agent against NAFLD and atherosclerosis. ..
  7. Yusoff N, Lim V, Al Hindi B, Abdul Razak K, Widyawati T, Anggraini D, et al. Nypa fruticans Wurmb. Vinegar's Aqueous Extract Stimulates Insulin Secretion and Exerts Hepatoprotective Effect on STZ-Induced Diabetic Rats. Nutrients. 2017;9: pubmed publisher
    ..1 mM). Nypa fruticans Wurmb. vinegar's aqueous extract exerts its antihyperglycaemic activity, at least in part, through insulin stimulatory and hepatoprotective effects. ..
  8. Bello I, Bakkouri A, Tabana Y, Al Hindi B, Al Mansoub M, Mahmud R, et al. Acute and Sub-Acute Toxicity Evaluation of the Methanolic Extract of Alstonia scholaris Stem Bark. Med Sci (Basel). 2016;4: pubmed publisher
    ..The long-term toxic effect was found to be associated with alterations in hematological compositions and end-organ damage to the liver. Thus, prolonged use of high doses of ASME orally should be discouraged and lower doses encouraged. ..
  9. Al Hindi B, Yusoff N, Atangwho I, Ahmad M, Asmawi M, Yam M. A Soxhlet Extract of Gongronema latifolium Retains Moderate Blood Glucose Lowering Effect and Produces Structural Recovery in the Pancreas of STZ-Induced Diabetic Rats. Med Sci (Basel). 2016;4: pubmed publisher
    ..Despite retaining moderate antidiabetic activity, Soxhlet extraction of Gongronema latifolium probably leads to the destruction of active heat-liable compounds. ..

More Information


  1. Mohamed E, Siddiqui M, Ang L, Sadikun A, Chan S, Tan S, et al. Potent ?-glucosidase and ?-amylase inhibitory activities of standardized 50% ethanolic extracts and sinensetin from Orthosiphon stamineus Benth as anti-diabetic mechanism. BMC Complement Altern Med. 2012;12:176 pubmed publisher
    ..In the present study, we tested a 50% ethanolic extract of Orthosiphon stamineus plants and its isolated bioactive compound with respect to their ?-glucosidase and ?-amylase inhibitory activities...