Seung Jae Myung
Affiliation: University of Ulsan
Pak S, Hwang S, Shim I, Bae S, Ryu Y, Kim H, et al
. Endoscopic Transplantation of Mesenchymal Stem Cell Sheets in Experimental Colitis in Rats. Sci Rep. 2018;8:11314 pubmed publisher
..Our results show that endoscopic transplantation of MSC sheets could be a new effective mode of stem cell therapy for IBD treatment. ..
Bae S, Park S, Choi M, Song M, Cho Y, Do E, et al
. PSP1, a Phosphatidylserine-Recognizing Peptide, Is Useful for Visualizing Radiation-Induced Apoptosis in Colorectal Cancer In Vitro and In Vivo. Transl Oncol. 2018;11:1044-1052 pubmed publisher
..534) and after (r2 = 0.848) radiation therapy. Our study shows that PSP1 peptide is an efficient index probe for deciding "go or no-go" for radiation therapy in colorectal cancer. ..
Cho C, Jung J, Jiang L, Lee E, Kim D, Kim B, et al
. Combinatory RNA-Sequencing Analyses Reveal a Dual Mode of Gene Regulation by ADAR1 in Gastric Cancer. Dig Dis Sci. 2018;63:1835-1850 pubmed publisher
..ADAR1 regulates post-transcriptional gene expression in gastric cancer through both RNA editing-dependent and editing-independent mechanisms. ..
Kang M, Choi H, Oshima M, Cheong J, Kim S, Lee J, et al
. Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer. Nat Commun. 2018;9:1920 pubmed publisher
..Our present findings thus demonstrate that ESRRG functions as a negative regulator of the Wnt signaling pathway in GC and is a potential therapeutic target for this cancer. ..
Cho C, Kang H, Ryu Y, Park Y, Jeong H, Park Y, et al
. Poor prognosis in Epstein-Barr virus-negative gastric cancer with lymphoid stroma is associated with immune phenotype. Gastric Cancer. 2018;: pubmed publisher
..TIL density may be a prognostic marker in patients with GCLS. ..
Park S, Bae D, Ryu Y, Kim S, Myung S, Kim H. Mitochondria-targeting ratiometric fluorescent probe for Î³-glutamyltranspeptidase and its application to colon cancer. Chem Commun (Camb). 2016;52:10400-2 pubmed publisher
..Further application was successful for the detection of cancerous colons in mice. ..
Chung E, Do E, Kim S, Cho E, Kim D, Pak S, et al
. Combination of metformin and VSL#3 additively suppresses western-style diet induced colon cancer in mice. Eur J Pharmacol. 2017;794:1-7 pubmed publisher
..A combination therapy with Met and V attenuates tumor growth in a mouse model of WD-induced colitic cancer, suggesting that this strategy could be useful for the chemoprevention of colon cancer. ..
Kim H, Kim M, Park Y, Park I, Kim T, Yang S, et al
. Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice. Gastroenterology. 2017;152:616-630 pubmed publisher
..This pathway promotes proliferation of colon cancer cell lines and colon tissue regeneration in mice with colitis. Constitutive activation of this pathway led to formation of polyps and colon tumors in mice. ..
Lee S, Kim M, Chang K, Song E, Hwang S, Park S, et al
. Fecal calprotectin predicts complete mucosal healing and better correlates with the ulcerative colitis endoscopic index of severity than with the Mayo endoscopic subscore in patients with ulcerative colitis. BMC Gastroenterol. 2017;17:110 pubmed publisher
..UCEIS exhibits a stronger correlation with the FC level, as compared to MES. Thus, FC could be used as a reliable noninvasive indicator for evaluating disease activity and mucosal healing in UC. ..